GREMLIN Database
YQJA - Inner membrane protein YqjA
UniProt: P0AA63 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12740
Length: 220 (190)
Sequences: 6789 (4824)
Seq/√Len: 350.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
84_W150_N3.4231.00
67_G70_Q3.0901.00
76_T162_L2.8211.00
202_F206_G2.5971.00
121_H124_S2.5081.00
204_L208_L2.4231.00
72_I166_L2.4221.00
80_S158_W2.4201.00
123_L152_R2.3821.00
61_I173_Y2.3651.00
205_A209_V2.3471.00
127_L159_M2.3241.00
84_W154_Q2.2771.00
102_W105_H2.2591.00
37_F85_V2.2091.00
149_N152_R2.1951.00
199_L203_G2.1631.00
190_S194_L2.1381.00
107_P110_Y1.9981.00
115_H119_H1.8991.00
24_M28_L1.8971.00
75_L165_V1.8921.00
68_Y170_T1.8791.00
123_L156_F1.8741.00
74_L78_A1.8431.00
91_R147_G1.8031.00
72_I169_T1.7341.00
33_F78_A1.7011.00
170_T174_M1.6931.00
95_N115_H1.6831.00
29_Y67_G1.6711.00
88_I92_W1.6481.00
54_L169_T1.6461.00
203_G207_S1.5841.00
37_F81_L1.5811.00
150_N154_Q1.5741.00
57_V71_T1.5651.00
68_Y72_I1.5631.00
36_L78_A1.5591.00
99_V108_A1.4701.00
108_A112_Q1.4691.00
131_F163_L1.4641.00
29_Y70_Q1.4591.00
32_L75_L1.4561.00
208_L211_L1.4531.00
68_Y169_T1.4401.00
201_V205_A1.4281.00
33_F74_L1.4201.00
88_I150_N1.4081.00
112_Q116_H1.4041.00
90_G145_L1.3781.00
124_S128_I1.3741.00
109_H113_R1.3711.00
184_Y187_Q1.3701.00
151_A155_F1.3521.00
71_T169_T1.3441.00
83_C130_R1.3301.00
27_M31_V1.3271.00
33_F77_V1.3271.00
61_I68_Y1.3211.00
129_G139_L1.3091.00
70_Q74_L1.3081.00
182_L186_D1.2981.00
185_E188_L1.2931.00
187_Q191_C1.2781.00
29_Y74_L1.2691.00
80_S161_G1.2491.00
179_P183_K1.2121.00
69_P73_L1.2101.00
126_L148_L1.2041.00
200_L203_G1.1991.00
198_V202_F1.1961.00
22_P25_I1.1911.00
39_E50_G1.1811.00
189_M193_M1.1741.00
191_C195_L1.1731.00
66_M71_T1.1691.00
54_L75_L1.1591.00
203_G206_G1.1501.00
186_D190_S1.1471.00
206_G210_V1.1461.00
115_H146_S1.1181.00
72_I170_T1.1171.00
95_N99_V1.1151.00
200_L204_L1.1151.00
101_N104_S1.1081.00
80_S154_Q1.0991.00
73_L77_V1.0921.00
69_P170_T1.0811.00
92_W96_T1.0491.00
112_Q115_H1.0461.00
102_W108_A1.0431.00
51_D136_R1.0311.00
155_F159_M1.0271.00
24_M31_V1.0251.00
45_A86_S1.0241.00
196_P199_L1.0111.00
163_L166_L1.0051.00
27_M30_F1.0041.00
207_S210_V1.0031.00
118_F143_A1.0021.00
205_A208_L0.9941.00
32_L71_T0.9891.00
84_W88_I0.9861.00
62_A173_Y0.9851.00
58_G172_G0.9821.00
98_T111_H0.9751.00
76_T80_S0.9671.00
76_T165_V0.9631.00
86_S141_T0.9591.00
54_L58_G0.9591.00
22_P26_G0.9521.00
29_Y66_M0.9511.00
136_R164_W0.9501.00
28_L31_V0.9491.00
98_T106_L0.9441.00
88_I91_R0.9441.00
96_T100_Q0.9261.00
207_S211_L0.9261.00
70_Q73_L0.9241.00
72_I76_T0.9101.00
77_V81_L0.9091.00
33_F81_L0.9051.00
140_P157_N0.9041.00
151_A154_Q0.9001.00
193_M197_V0.8991.00
157_N161_G0.8931.00
23_S28_L0.8931.00
83_C157_N0.8911.00
184_Y188_L0.8881.00
127_L163_L0.8871.00
58_G169_T0.8811.00
73_L76_T0.8761.00
103_L106_L0.8731.00
116_H120_K0.8721.00
122_G148_L0.8691.00
94_G98_T0.8671.00
114_A146_S0.8661.00
110_Y113_R0.8621.00
171_L174_M0.8571.00
206_G209_V0.8511.00
177_K180_V0.8481.00
75_L169_T0.8351.00
192_L196_P0.8321.00
32_L57_V0.8291.00
69_P72_I0.8281.00
93_L96_T0.8271.00
199_L202_F0.8251.00
26_G30_F0.8251.00
167_I170_T0.8231.00
79_A161_G0.8231.00
188_L191_C0.8171.00
154_Q158_W0.8131.00
117_L125_A0.8011.00
203_G208_L0.8001.00
79_A130_R0.8001.00
58_G71_T0.7971.00
89_Q93_L0.7891.00
166_L170_T0.7881.00
84_W157_N0.7861.00
193_M196_P0.7851.00
155_F158_W0.7841.00
61_I71_T0.7821.00
97_R101_N0.7781.00
93_L97_R0.7731.00
38_L46_A0.7701.00
180_V184_Y0.7701.00
181_F184_Y0.7671.00
183_K187_Q0.7371.00
180_V183_K0.7341.00
19_L23_S0.7280.99
59_V178_T0.7270.99
36_L165_V0.7240.99
195_L199_L0.7240.99
202_F205_A0.7210.99
56_L60_L0.7090.99
175_L180_V0.7080.99
189_M196_P0.7040.99
28_L66_M0.7030.99
130_R136_R0.7030.99
132_I135_V0.7010.99
179_P182_L0.7000.99
86_S137_T0.6980.99
40_N44_P0.6970.99
125_A139_L0.6920.99
113_R116_H0.6890.99
24_M27_M0.6890.99
35_I53_L0.6880.99
48_L137_T0.6870.99
40_N130_R0.6860.99
124_S156_F0.6840.99
59_V62_A0.6810.99
80_S157_N0.6800.99
143_A148_L0.6800.99
101_N106_L0.6780.99
191_C194_L0.6770.99
175_L178_T0.6770.99
125_A128_I0.6760.99
83_C150_N0.6740.99
106_L110_Y0.6690.99
47_F134_F0.6650.99
62_A65_A0.6600.99
158_W162_L0.6450.99
23_S31_V0.6440.99
54_L165_V0.6390.99
162_L166_L0.6370.99
25_I28_L0.6320.99
61_I169_T0.6300.98
38_L45_A0.6300.98
87_Y150_N0.6260.98
136_R161_G0.6210.98
56_L59_V0.6210.98
21_N25_I0.6170.98
167_I171_L0.6170.98
98_T103_L0.6120.98
87_Y144_G0.6090.98
182_L185_E0.6090.98
36_L75_L0.6080.98
144_G147_G0.6080.98
57_V66_M0.6040.98
46_A86_S0.6010.98
194_L198_V0.6010.98
152_R156_F0.6010.98
201_V204_L0.5990.98
133_A137_T0.5940.98
100_Q103_L0.5930.98
141_T145_L0.5900.98
196_P200_L0.5850.98
109_H112_Q0.5770.97
51_D168_L0.5740.97
163_L167_I0.5720.97
186_D189_M0.5700.97
39_E136_R0.5680.97
50_G133_A0.5680.97
165_V169_T0.5640.97
40_N83_C0.5640.97
50_G157_N0.5620.97
202_F208_L0.5610.97
40_N157_N0.5580.97
23_S27_M0.5530.97
197_V201_V0.5500.96
39_E164_W0.5490.96
98_T145_L0.5480.96
118_F125_A0.5480.96
116_H119_H0.5470.96
97_R102_W0.5470.96
85_V88_I0.5410.96
79_A137_T0.5400.96
94_G97_R0.5370.96
174_M177_K0.5350.96
51_D160_S0.5320.96
87_Y147_G0.5320.96
95_N98_T0.5320.96
81_L85_V0.5310.96
46_A137_T0.5300.96
129_G133_A0.5290.96
21_N28_L0.5270.96
32_L74_L0.5260.95
86_S134_F0.5250.95
200_L207_S0.5240.95
33_F37_F0.5240.95
39_E157_N0.5210.95
130_R157_N0.5170.95
159_M162_L0.5160.95
194_L197_V0.5150.95
191_C206_G0.5140.95
127_L131_F0.5140.95
117_L121_H0.5120.95
125_A160_S0.5120.95
68_Y166_L0.5110.95
85_V89_Q0.5110.95
40_N137_T0.5100.95
56_L185_E0.5100.95
36_L137_T0.5090.95
180_V188_L0.5080.95
39_E137_T0.5070.95
39_E130_R0.5060.94
102_W107_P0.5050.94
54_L79_A0.5050.94
137_T168_L0.5040.94
110_Y114_A0.5020.94
133_A157_N0.5020.94
62_A176_G0.5020.94
57_V61_I0.5000.94
196_P206_G0.5000.94
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4dx5A 3 0.8273 58.5 0.922 Contact Map
3w9iA 3 0.7773 52.2 0.925 Contact Map
2kluA 1 0.2045 45.8 0.928 Contact Map
2l2tA 2 0.1955 41.2 0.93 Contact Map
2m20A 2 0.1864 41.1 0.93 Contact Map
3wdoA 1 0.8818 33.6 0.933 Contact Map
3ne5A 3 0.8182 33.5 0.933 Contact Map
4k0jA 3 0.7636 32.7 0.933 Contact Map
3aqpA 1 0.7818 29 0.935 Contact Map
2cfqA 1 0.9545 28 0.936 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0079 seconds.