YQJA - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

YQJA - Inner membrane protein YqjA

UniProt:	P0AA63	Sequences: MELLTQLLQALWAQDFETLANPSMIGMLYFVLFVILFLENGLLPAAFLPGDSLLVLVGVLIAKGAMGYPQTILLLTVAASLGCWVSYIQGRWLGNTRTVQNWLSHLPAHYHQRAHHLFHKHGLSALLIGRFIAFVRTLLPTIAGLSGLNNARFQFFNWMSGLLWVLILTTLGYMLGKTPVFLKYEDQLMSCLMLLPVVLLVFGLAGSLVVLWKKKYGNRG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12740
Length:	220 (190)
Sequences:	6789 (4824)
Seq/√Len:	350.0

ECOLI - YQJA YGHB DEDA YABI YOHD YDJZ YDJX
BACSU - YKOX YNGC YBFM YHJE YQED YTXB
SULSO - Q97V45

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
84_W	150_N	3.423	1.00
67_G	70_Q	3.090	1.00
76_T	162_L	2.821	1.00
202_F	206_G	2.597	1.00
121_H	124_S	2.508	1.00
204_L	208_L	2.423	1.00
72_I	166_L	2.422	1.00
80_S	158_W	2.420	1.00
123_L	152_R	2.382	1.00
61_I	173_Y	2.365	1.00
205_A	209_V	2.347	1.00
127_L	159_M	2.324	1.00
84_W	154_Q	2.277	1.00
102_W	105_H	2.259	1.00
37_F	85_V	2.209	1.00
149_N	152_R	2.195	1.00
199_L	203_G	2.163	1.00
190_S	194_L	2.138	1.00
107_P	110_Y	1.998	1.00
115_H	119_H	1.899	1.00
24_M	28_L	1.897	1.00
75_L	165_V	1.892	1.00
68_Y	170_T	1.879	1.00
123_L	156_F	1.874	1.00
74_L	78_A	1.843	1.00
91_R	147_G	1.803	1.00
72_I	169_T	1.734	1.00
33_F	78_A	1.701	1.00
170_T	174_M	1.693	1.00
95_N	115_H	1.683	1.00
29_Y	67_G	1.671	1.00
88_I	92_W	1.648	1.00
54_L	169_T	1.646	1.00
203_G	207_S	1.584	1.00
37_F	81_L	1.581	1.00
150_N	154_Q	1.574	1.00
57_V	71_T	1.565	1.00
68_Y	72_I	1.563	1.00
36_L	78_A	1.559	1.00
99_V	108_A	1.470	1.00
108_A	112_Q	1.469	1.00
131_F	163_L	1.464	1.00
29_Y	70_Q	1.459	1.00
32_L	75_L	1.456	1.00
208_L	211_L	1.453	1.00
68_Y	169_T	1.440	1.00
201_V	205_A	1.428	1.00
33_F	74_L	1.420	1.00
88_I	150_N	1.408	1.00
112_Q	116_H	1.404	1.00
90_G	145_L	1.378	1.00
124_S	128_I	1.374	1.00
109_H	113_R	1.371	1.00
184_Y	187_Q	1.370	1.00
151_A	155_F	1.352	1.00
71_T	169_T	1.344	1.00
83_C	130_R	1.330	1.00
27_M	31_V	1.327	1.00
33_F	77_V	1.327	1.00
61_I	68_Y	1.321	1.00
129_G	139_L	1.309	1.00
70_Q	74_L	1.308	1.00
182_L	186_D	1.298	1.00
185_E	188_L	1.293	1.00
187_Q	191_C	1.278	1.00
29_Y	74_L	1.269	1.00
80_S	161_G	1.249	1.00
179_P	183_K	1.212	1.00
69_P	73_L	1.210	1.00
126_L	148_L	1.204	1.00
200_L	203_G	1.199	1.00
198_V	202_F	1.196	1.00
22_P	25_I	1.191	1.00
39_E	50_G	1.181	1.00
189_M	193_M	1.174	1.00
191_C	195_L	1.173	1.00
66_M	71_T	1.169	1.00
54_L	75_L	1.159	1.00
203_G	206_G	1.150	1.00
186_D	190_S	1.147	1.00
206_G	210_V	1.146	1.00
115_H	146_S	1.118	1.00
72_I	170_T	1.117	1.00
95_N	99_V	1.115	1.00
200_L	204_L	1.115	1.00
101_N	104_S	1.108	1.00
80_S	154_Q	1.099	1.00
73_L	77_V	1.092	1.00
69_P	170_T	1.081	1.00
92_W	96_T	1.049	1.00
112_Q	115_H	1.046	1.00
102_W	108_A	1.043	1.00
51_D	136_R	1.031	1.00
155_F	159_M	1.027	1.00
24_M	31_V	1.025	1.00
45_A	86_S	1.024	1.00
196_P	199_L	1.011	1.00
163_L	166_L	1.005	1.00
27_M	30_F	1.004	1.00
207_S	210_V	1.003	1.00
118_F	143_A	1.002	1.00
205_A	208_L	0.994	1.00
32_L	71_T	0.989	1.00
84_W	88_I	0.986	1.00
62_A	173_Y	0.985	1.00
58_G	172_G	0.982	1.00
98_T	111_H	0.975	1.00
76_T	80_S	0.967	1.00
76_T	165_V	0.963	1.00
86_S	141_T	0.959	1.00
54_L	58_G	0.959	1.00
22_P	26_G	0.952	1.00
29_Y	66_M	0.951	1.00
136_R	164_W	0.950	1.00
28_L	31_V	0.949	1.00
98_T	106_L	0.944	1.00
88_I	91_R	0.944	1.00
96_T	100_Q	0.926	1.00
207_S	211_L	0.926	1.00
70_Q	73_L	0.924	1.00
72_I	76_T	0.910	1.00
77_V	81_L	0.909	1.00
33_F	81_L	0.905	1.00
140_P	157_N	0.904	1.00
151_A	154_Q	0.900	1.00
193_M	197_V	0.899	1.00
157_N	161_G	0.893	1.00
23_S	28_L	0.893	1.00
83_C	157_N	0.891	1.00
184_Y	188_L	0.888	1.00
127_L	163_L	0.887	1.00
58_G	169_T	0.881	1.00
73_L	76_T	0.876	1.00
103_L	106_L	0.873	1.00
116_H	120_K	0.872	1.00
122_G	148_L	0.869	1.00
94_G	98_T	0.867	1.00
114_A	146_S	0.866	1.00
110_Y	113_R	0.862	1.00
171_L	174_M	0.857	1.00
206_G	209_V	0.851	1.00
177_K	180_V	0.848	1.00
75_L	169_T	0.835	1.00
192_L	196_P	0.832	1.00
32_L	57_V	0.829	1.00
69_P	72_I	0.828	1.00
93_L	96_T	0.827	1.00
199_L	202_F	0.825	1.00
26_G	30_F	0.825	1.00
167_I	170_T	0.823	1.00
79_A	161_G	0.823	1.00
188_L	191_C	0.817	1.00
154_Q	158_W	0.813	1.00
117_L	125_A	0.801	1.00
203_G	208_L	0.800	1.00
79_A	130_R	0.800	1.00
58_G	71_T	0.797	1.00
89_Q	93_L	0.789	1.00
166_L	170_T	0.788	1.00
84_W	157_N	0.786	1.00
193_M	196_P	0.785	1.00
155_F	158_W	0.784	1.00
61_I	71_T	0.782	1.00
97_R	101_N	0.778	1.00
93_L	97_R	0.773	1.00
38_L	46_A	0.770	1.00
180_V	184_Y	0.770	1.00
181_F	184_Y	0.767	1.00
183_K	187_Q	0.737	1.00
180_V	183_K	0.734	1.00
19_L	23_S	0.728	0.99
59_V	178_T	0.727	0.99
36_L	165_V	0.724	0.99
195_L	199_L	0.724	0.99
202_F	205_A	0.721	0.99
56_L	60_L	0.709	0.99
175_L	180_V	0.708	0.99
189_M	196_P	0.704	0.99
28_L	66_M	0.703	0.99
130_R	136_R	0.703	0.99
132_I	135_V	0.701	0.99
179_P	182_L	0.700	0.99
86_S	137_T	0.698	0.99
40_N	44_P	0.697	0.99
125_A	139_L	0.692	0.99
113_R	116_H	0.689	0.99
24_M	27_M	0.689	0.99
35_I	53_L	0.688	0.99
48_L	137_T	0.687	0.99
40_N	130_R	0.686	0.99
124_S	156_F	0.684	0.99
59_V	62_A	0.681	0.99
80_S	157_N	0.680	0.99
143_A	148_L	0.680	0.99
101_N	106_L	0.678	0.99
191_C	194_L	0.677	0.99
175_L	178_T	0.677	0.99
125_A	128_I	0.676	0.99
83_C	150_N	0.674	0.99
106_L	110_Y	0.669	0.99
47_F	134_F	0.665	0.99
62_A	65_A	0.660	0.99
158_W	162_L	0.645	0.99
23_S	31_V	0.644	0.99
54_L	165_V	0.639	0.99
162_L	166_L	0.637	0.99
25_I	28_L	0.632	0.99
61_I	169_T	0.630	0.98
38_L	45_A	0.630	0.98
87_Y	150_N	0.626	0.98
136_R	161_G	0.621	0.98
56_L	59_V	0.621	0.98
21_N	25_I	0.617	0.98
167_I	171_L	0.617	0.98
98_T	103_L	0.612	0.98
87_Y	144_G	0.609	0.98
182_L	185_E	0.609	0.98
36_L	75_L	0.608	0.98
144_G	147_G	0.608	0.98
57_V	66_M	0.604	0.98
46_A	86_S	0.601	0.98
194_L	198_V	0.601	0.98
152_R	156_F	0.601	0.98
201_V	204_L	0.599	0.98
133_A	137_T	0.594	0.98
100_Q	103_L	0.593	0.98
141_T	145_L	0.590	0.98
196_P	200_L	0.585	0.98
109_H	112_Q	0.577	0.97
51_D	168_L	0.574	0.97
163_L	167_I	0.572	0.97
186_D	189_M	0.570	0.97
39_E	136_R	0.568	0.97
50_G	133_A	0.568	0.97
165_V	169_T	0.564	0.97
40_N	83_C	0.564	0.97
50_G	157_N	0.562	0.97
202_F	208_L	0.561	0.97
40_N	157_N	0.558	0.97
23_S	27_M	0.553	0.97
197_V	201_V	0.550	0.96
39_E	164_W	0.549	0.96
98_T	145_L	0.548	0.96
118_F	125_A	0.548	0.96
116_H	119_H	0.547	0.96
97_R	102_W	0.547	0.96
85_V	88_I	0.541	0.96
79_A	137_T	0.540	0.96
94_G	97_R	0.537	0.96
174_M	177_K	0.535	0.96
51_D	160_S	0.532	0.96
87_Y	147_G	0.532	0.96
95_N	98_T	0.532	0.96
81_L	85_V	0.531	0.96
46_A	137_T	0.530	0.96
129_G	133_A	0.529	0.96
21_N	28_L	0.527	0.96
32_L	74_L	0.526	0.95
86_S	134_F	0.525	0.95
200_L	207_S	0.524	0.95
33_F	37_F	0.524	0.95
39_E	157_N	0.521	0.95
130_R	157_N	0.517	0.95
159_M	162_L	0.516	0.95
194_L	197_V	0.515	0.95
191_C	206_G	0.514	0.95
127_L	131_F	0.514	0.95
117_L	121_H	0.512	0.95
125_A	160_S	0.512	0.95
68_Y	166_L	0.511	0.95
85_V	89_Q	0.511	0.95
40_N	137_T	0.510	0.95
56_L	185_E	0.510	0.95
36_L	137_T	0.509	0.95
180_V	188_L	0.508	0.95
39_E	137_T	0.507	0.95
39_E	130_R	0.506	0.94
102_W	107_P	0.505	0.94
54_L	79_A	0.505	0.94
137_T	168_L	0.504	0.94
110_Y	114_A	0.502	0.94
133_A	157_N	0.502	0.94
62_A	176_G	0.502	0.94
57_V	61_I	0.500	0.94
196_P	206_G	0.500	0.94

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4dx5A	3	0.8273	58.5	0.922	Contact Map
3w9iA	3	0.7773	52.2	0.925	Contact Map
2kluA	1	0.2045	45.8	0.928	Contact Map
2l2tA	2	0.1955	41.2	0.93	Contact Map
2m20A	2	0.1864	41.1	0.93	Contact Map
3wdoA	1	0.8818	33.6	0.933	Contact Map
3ne5A	3	0.8182	33.5	0.933	Contact Map
4k0jA	3	0.7636	32.7	0.933	Contact Map
3aqpA	1	0.7818	29	0.935	Contact Map
2cfqA	1	0.9545	28	0.936	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.008 seconds.