GREMLIN Database
YOBA - Protein YobA
UniProt: P0AA57 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG14029
Length: 124 (109)
Sequences: 1970 (1561)
Seq/√Len: 149.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
30_L50_L5.2671.00
28_A54_E3.6601.00
24_V113_H3.4901.00
76_L90_V3.1721.00
51_N87_Q2.8811.00
24_V54_E2.7051.00
97_K101_Y2.4301.00
47_A91_P2.2911.00
81_N84_D2.0421.00
32_H51_N1.9761.00
33_Q119_Y1.9191.00
54_E113_H1.9151.00
29_H53_S1.7361.00
67_G71_E1.7331.00
65_I103_V1.6791.00
17_T20_V1.6781.00
30_L33_Q1.6761.00
33_Q37_A1.6461.00
105_W117_G1.6001.00
55_G86_K1.5991.00
118_H121_F1.5861.00
107_V110_V1.5731.00
34_Y47_A1.5261.00
28_A53_S1.4371.00
56_V110_V1.4061.00
40_Q122_S1.3871.00
67_G70_N1.3391.00
66_T102_T1.3261.00
39_A42_T1.3121.00
57_E60_F1.2981.00
103_V119_Y1.2921.00
31_T53_S1.2861.00
62_G106_H1.2691.00
109_S113_H1.2581.00
79_K91_P1.2491.00
108_V111_D1.2431.00
63_A67_G1.1861.00
15_L19_L1.1801.00
34_Y49_T1.1220.99
66_T72_N1.1130.99
50_L103_V1.0790.99
33_Q50_L1.0720.99
44_A95_S1.0520.99
44_A98_P1.0460.99
119_Y122_S1.0460.99
50_L121_F1.0420.99
35_P103_V1.0380.99
65_I96_L1.0360.99
47_A89_I1.0310.99
84_D88_L1.0210.99
15_L18_S1.0000.99
65_I92_L0.9970.99
73_I96_L0.9960.99
92_L96_L0.9900.99
103_V121_F0.9760.99
54_E111_D0.9650.98
81_N85_Q0.9640.98
63_A103_V0.9380.98
79_K82_E0.9350.98
64_K104_D0.9330.98
106_H109_S0.9120.98
81_N87_Q0.9090.98
108_V115_T0.9040.98
50_L63_A0.8990.97
105_W109_S0.8980.97
49_T87_Q0.8920.97
81_N89_I0.8840.97
91_P95_S0.8800.97
92_L95_S0.8740.97
80_R85_Q0.8720.97
30_L119_Y0.8610.97
16_T20_V0.8540.97
70_N73_I0.8510.96
66_T104_D0.8420.96
47_A95_S0.8390.96
56_V109_S0.8380.96
26_A113_H0.8260.96
73_I97_K0.8200.96
48_I65_I0.8150.96
96_L101_Y0.7940.95
64_K67_G0.7930.95
17_T24_V0.7920.95
34_Y46_Q0.7900.95
57_E110_V0.7880.95
24_V28_A0.7860.95
112_G115_T0.7820.94
49_T89_I0.7790.94
56_V59_G0.7740.94
72_N79_K0.7680.94
13_A20_V0.7630.94
104_D118_H0.7610.94
80_R84_D0.7460.93
102_T120_T0.7460.93
21_T25_W0.7360.92
41_V45_P0.7310.92
33_Q48_I0.7300.92
56_V88_L0.7250.92
62_G108_V0.7150.91
31_T85_Q0.7050.91
48_I103_V0.7020.90
18_S22_P0.7010.90
53_S110_V0.6990.90
63_A90_V0.6990.90
56_V61_S0.6990.90
15_L75_T0.6970.90
64_K74_K0.6970.90
78_A81_N0.6950.90
100_T122_S0.6860.89
24_V109_S0.6840.89
67_G97_K0.6740.89
106_H114_K0.6690.88
13_A17_T0.6660.88
14_I17_T0.6640.88
28_A62_G0.6620.88
41_V93_A0.6570.87
101_Y117_G0.6560.87
13_A16_T0.6460.86
113_H117_G0.6440.86
13_A120_T0.6390.86
50_L105_W0.6220.84
85_Q89_I0.6180.84
18_S21_T0.6180.84
74_K93_A0.6150.84
43_A46_Q0.6140.84
17_T21_T0.6100.83
37_A41_V0.6060.83
56_V80_R0.6000.82
61_S80_R0.5860.81
71_E74_K0.5860.81
81_N86_K0.5850.81
58_T80_R0.5810.80
24_V27_H0.5800.80
31_T51_N0.5770.80
85_Q88_L0.5730.79
34_Y51_N0.5730.79
82_E86_K0.5720.79
37_A119_Y0.5700.79
92_L116_K0.5690.79
27_H113_H0.5670.79
27_H53_S0.5640.78
98_P108_V0.5630.78
61_S78_A0.5610.78
89_I92_L0.5570.77
29_H32_H0.5570.77
27_H107_V0.5530.77
27_H44_A0.5530.77
18_S52_F0.5520.77
65_I114_K0.5480.76
52_F56_V0.5420.75
73_I90_V0.5390.75
40_Q100_T0.5360.75
66_T118_H0.5340.74
56_V96_L0.5340.74
111_D117_G0.5320.74
61_S108_V0.5290.74
27_H117_G0.5210.73
63_A88_L0.5210.73
75_T93_A0.5110.71
33_Q103_V0.5100.71
36_A39_A0.5070.70
80_R88_L0.5040.70
33_Q46_Q0.5010.70
55_G79_K0.5000.69
56_V60_F0.5000.69
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2c9rA 1 0.7661 99.5 0.406 Contact Map
1lyqA 1 0.7903 99.5 0.406 Contact Map
4hu2A 1 0.7097 98.6 0.605 Contact Map
4qtfA 2 0.7016 98.1 0.657 Contact Map
4ziqA 2 0 94.1 0.78 Contact Map
3vypA 1 0.8226 93.5 0.786 Contact Map
4zjgA 1 0.7903 90.9 0.802 Contact Map
4k73A 1 0.7097 90.1 0.805 Contact Map
4aq1A 1 0.7016 89.6 0.807 Contact Map
2ra1A 1 0.9355 86.9 0.816 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0052 seconds.