PLAP - ECOLI - GREMLIN Contacts

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PLAP - Low-affinity putrescine importer PlaP

UniProt:	P0AA47	Sequences: MSHNVTPNTSRVELRKTLTLVPVVMMGLAYMQPMTLFDTFGIVSGLTDGHVPTAYAFALIAILFTALSYGKLVRRYPSAGSAYTYAQKSISPTVGFMVGWSSLLDYLFAPMINILLAKIYFEALVPSIPSWMFVVALVAFMTAFNLRSLKSVANFNTVIVVLQVVLIAVILGMVVYGVFEGEGAGTLASTRPFWSGDAHVIPMITGATILCFSFTGFDGISNLSEETKDAERVIPRAIFLTALIGGMIFIFATYFLQLYFPDISRFKDPDASQPEIMLYVAGKAFQVGALIFSTITVLASGMAAHAGVARLMYVMGRDGVFPKSFFGYVHPKWRTPAMNIILVGAIALLAINFDLVMATALINFGALVAFTFVNLSVISQFWIREKRNKTLKDHFQYLFLPMCGALTVGALWVNLEESSMVLGLIWAAIGLIYLACVTKSFRNPVPQYEDVA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11896
Length:	452 (419)
Sequences:	24865 (16359)
Seq/√Len:	799.2

ECOLI - PLAP PUUP LYSP PROY AROP GABP MMUP ANSP FRLA POTE PHEP ADIC YIFK CYCA YBAT GADC YCAM ARCD CADB YGJI YJEM YJEH TNAB
BACSU - YTNA YBGF YHDG GABP YBXG YDGF ASPP HUTM YBEC ROCC YFNA ROCE AAPA YVBW STET YCGH ARCD YECA YDAO GERBB GERAB YNDE GERKB YFKT
HALSA - Q9HHU7 Q9HQB3 Q9HSL5
SULSO - Q97X49 Q97XM0 Q97U05 Q97WS3 Q97Z63 Q7LXI7 Q97ZB5 Q97VA8 Q97VA6 Q97WD4 Q97U33 Q97VR4 Q97Y76 Q97YN3 Q97YX9 Q97U39

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
142_T	344_G	4.303	1.00
325_F	338_M	3.925	1.00
59_L	246_G	3.205	1.00
379_S	383_I	3.117	1.00
328_Y	338_M	3.049	1.00
232_R	236_R	3.011	1.00
19_T	228_K	2.899	1.00
330_H	333_W	2.890	1.00
83_Y	318_D	2.808	1.00
227_T	233_V	2.738	1.00
174_V	255_F	2.694	1.00
99_G	315_M	2.690	1.00
316_G	327_G	2.580	1.00
229_D	232_R	2.559	1.00
330_H	337_A	2.465	1.00
225_E	317_R	2.433	1.00
24_V	240_L	2.410	1.00
371_T	405_A	2.401	1.00
172_G	176_Y	2.385	1.00
135_V	348_L	2.361	1.00
71_K	381_F	2.338	1.00
20_L	240_L	2.334	1.00
87_Q	95_G	2.318	1.00
341_I	345_A	2.244	1.00
226_E	310_R	2.195	1.00
397_Y	401_P	2.142	1.00
20_L	233_V	2.140	1.00
402_M	406_L	2.118	1.00
313_Y	317_R	2.102	1.00
20_L	24_V	2.096	1.00
143_A	147_R	2.063	1.00
23_V	227_T	2.057	1.00
150_K	154_N	2.053	1.00
142_T	340_I	2.044	1.00
319_G	323_K	1.997	1.00
139_A	348_L	1.979	1.00
284_A	288_G	1.977	1.00
90_I	379_S	1.970	1.00
146_L	337_A	1.963	1.00
275_E	278_L	1.951	1.00
236_R	240_L	1.947	1.00
134_V	351_I	1.946	1.00
391_L	394_H	1.939	1.00
14_L	329_V	1.936	1.00
103_L	343_V	1.924	1.00
87_Q	92_P	1.922	1.00
19_T	22_P	1.917	1.00
135_V	351_I	1.913	1.00
432_I	436_C	1.899	1.00
161_V	165_V	1.888	1.00
60_I	64_F	1.873	1.00
399_F	403_C	1.832	1.00
68_S	374_N	1.815	1.00
374_N	404_G	1.798	1.00
330_H	335_T	1.798	1.00
326_F	342_L	1.789	1.00
90_I	375_L	1.785	1.00
43_V	51_V	1.785	1.00
229_D	233_V	1.749	1.00
388_N	391_L	1.745	1.00
239_F	243_L	1.727	1.00
145_N	302_M	1.725	1.00
100_W	430_G	1.712	1.00
54_A	206_G	1.701	1.00
22_P	157_T	1.697	1.00
98_V	372_F	1.671	1.00
114_I	301_G	1.652	1.00
146_L	341_I	1.644	1.00
86_A	98_V	1.638	1.00
333_W	337_A	1.634	1.00
379_S	382_W	1.633	1.00
406_L	410_A	1.623	1.00
27_G	241_T	1.617	1.00
275_E	279_Y	1.611	1.00
265_R	279_Y	1.610	1.00
165_V	169_V	1.608	1.00
24_V	244_I	1.603	1.00
139_A	344_G	1.597	1.00
129_P	132_M	1.589	1.00
138_V	347_A	1.586	1.00
110_P	347_A	1.579	1.00
426_W	430_G	1.552	1.00
18_L	22_P	1.552	1.00
189_S	195_S	1.530	1.00
243_L	247_M	1.524	1.00
338_M	342_L	1.519	1.00
121_F	133_F	1.515	1.00
229_D	236_R	1.513	1.00
164_V	168_A	1.512	1.00
91_S	94_V	1.502	1.00
192_P	195_S	1.491	1.00
58_A	210_L	1.483	1.00
223_L	306_A	1.475	1.00
389_K	393_D	1.473	1.00
117_A	294_T	1.473	1.00
424_L	428_A	1.468	1.00
408_V	411_L	1.455	1.00
128_I	132_M	1.449	1.00
114_I	138_V	1.445	1.00
79_A	225_E	1.435	1.00
313_Y	329_V	1.435	1.00
189_S	192_P	1.431	1.00
147_R	333_W	1.429	1.00
47_T	50_H	1.428	1.00
66_A	242_A	1.427	1.00
391_L	395_F	1.422	1.00
308_V	343_V	1.418	1.00
166_L	292_F	1.413	1.00
192_P	196_G	1.396	1.00
436_C	439_K	1.390	1.00
14_L	313_Y	1.382	1.00
401_P	405_A	1.382	1.00
312_M	339_N	1.380	1.00
417_E	420_M	1.378	1.00
230_A	235_P	1.376	1.00
382_W	385_E	1.374	1.00
431_L	435_A	1.374	1.00
142_T	341_I	1.367	1.00
175_V	255_F	1.361	1.00
22_P	153_A	1.357	1.00
138_V	344_G	1.354	1.00
90_I	94_V	1.347	1.00
135_V	139_A	1.345	1.00
15_R	334_R	1.332	1.00
309_A	340_I	1.325	1.00
60_I	403_C	1.313	1.00
66_A	238_I	1.313	1.00
18_L	23_V	1.305	1.00
375_L	379_S	1.295	1.00
38_D	116_L	1.290	1.00
381_F	385_E	1.283	1.00
76_Y	88_K	1.279	1.00
18_L	153_A	1.276	1.00
261_P	265_R	1.272	1.00
190_T	195_S	1.271	1.00
323_K	327_G	1.271	1.00
398_L	402_M	1.270	1.00
328_Y	337_A	1.268	1.00
312_M	321_F	1.266	1.00
65_T	374_N	1.265	1.00
86_A	372_F	1.264	1.00
278_L	286_Q	1.263	1.00
401_P	408_V	1.262	1.00
171_L	251_F	1.250	1.00
435_A	439_K	1.246	1.00
384_R	387_R	1.245	1.00
269_P	275_E	1.243	1.00
247_M	251_F	1.241	1.00
404_G	408_V	1.240	1.00
278_L	283_K	1.227	1.00
52_P	254_Y	1.227	1.00
420_M	423_G	1.227	1.00
189_S	194_W	1.226	1.00
117_A	137_L	1.222	1.00
61_A	407_T	1.221	1.00
404_G	407_T	1.221	1.00
64_F	403_C	1.216	1.00
416_E	419_S	1.214	1.00
178_V	258_L	1.213	1.00
113_N	300_S	1.207	1.00
67_L	239_F	1.206	1.00
425_I	429_I	1.205	1.00
233_V	236_R	1.202	1.00
389_K	392_K	1.198	1.00
84_T	88_K	1.196	1.00
21_V	25_M	1.194	1.00
417_E	421_V	1.188	1.00
31_M	245_G	1.186	1.00
261_P	264_S	1.179	1.00
131_W	135_V	1.171	1.00
103_L	312_M	1.170	1.00
174_V	259_Y	1.170	1.00
20_L	236_R	1.169	1.00
193_F	196_G	1.160	1.00
430_G	433_Y	1.159	1.00
144_F	155_F	1.159	1.00
176_Y	181_G	1.153	1.00
323_K	328_Y	1.150	1.00
69_Y	82_A	1.150	1.00
141_M	301_G	1.144	1.00
428_A	432_I	1.144	1.00
433_Y	436_C	1.141	1.00
329_V	334_R	1.141	1.00
93_T	437_V	1.140	1.00
170_I	174_V	1.130	1.00
338_M	341_I	1.122	1.00
179_F	182_E	1.121	1.00
132_M	136_A	1.118	1.00
146_L	335_T	1.115	1.00
73_V	85_Y	1.115	1.00
169_V	173_M	1.111	1.00
71_K	74_R	1.106	1.00
28_L	244_I	1.105	1.00
281_A	285_F	1.102	1.00
156_N	302_M	1.101	1.00
96_F	100_W	1.100	1.00
136_A	140_F	1.095	1.00
86_A	94_V	1.092	1.00
401_P	407_T	1.088	1.00
27_G	220_I	1.087	1.00
409_G	413_V	1.087	1.00
23_V	237_A	1.083	1.00
89_S	376_S	1.077	1.00
78_S	84_T	1.076	1.00
375_L	405_A	1.076	1.00
287_V	291_I	1.074	1.00
44_S	51_V	1.071	1.00
418_S	422_L	1.068	1.00
83_Y	314_V	1.067	1.00
168_A	172_G	1.060	1.00
121_F	125_V	1.052	1.00
261_P	279_Y	1.048	1.00
155_F	159_I	1.047	1.00
175_V	179_F	1.046	1.00
408_V	412_W	1.044	1.00
228_K	233_V	1.041	1.00
17_T	228_K	1.034	1.00
282_G	285_F	1.034	1.00
422_L	425_I	1.031	1.00
26_M	223_L	1.028	1.00
418_S	421_V	1.026	1.00
142_T	146_L	1.018	1.00
399_F	402_M	1.017	1.00
88_K	384_R	1.014	1.00
154_N	158_V	1.014	1.00
269_P	272_S	1.009	1.00
68_S	401_P	1.009	1.00
410_A	413_V	1.008	1.00
345_A	349_L	1.008	1.00
371_T	375_L	1.007	1.00
317_R	327_G	1.006	1.00
190_T	193_F	1.003	1.00
199_H	202_P	1.002	1.00
75_R	387_R	0.998	1.00
188_A	191_R	0.995	1.00
56_A	250_I	0.989	1.00
28_L	245_G	0.988	1.00
139_A	143_A	0.987	1.00
170_I	277_M	0.986	1.00
390_T	394_H	0.974	1.00
397_Y	400_L	0.970	1.00
146_L	330_H	0.969	1.00
176_Y	180_E	0.960	1.00
407_T	411_L	0.959	1.00
398_L	401_P	0.955	1.00
433_Y	437_V	0.954	1.00
421_V	425_I	0.953	1.00
121_F	294_T	0.953	1.00
200_V	203_M	0.951	1.00
430_G	434_L	0.948	1.00
118_K	133_F	0.944	1.00
325_F	328_Y	0.943	1.00
118_K	134_V	0.940	1.00
188_A	192_P	0.937	1.00
14_L	226_E	0.935	1.00
218_D	222_N	0.935	1.00
78_S	88_K	0.934	1.00
59_L	214_F	0.933	1.00
429_I	433_Y	0.927	1.00
224_S	234_I	0.926	1.00
171_L	255_F	0.923	1.00
149_L	306_A	0.923	1.00
189_S	196_G	0.921	1.00
385_E	389_K	0.920	1.00
14_L	310_R	0.919	1.00
164_V	248_I	0.916	1.00
420_M	424_L	0.916	1.00
141_M	302_M	0.911	1.00
191_R	195_S	0.910	1.00
259_Y	276_I	0.909	1.00
401_P	413_V	0.906	1.00
93_T	97_M	0.906	1.00
405_A	408_V	0.897	1.00
401_P	412_W	0.896	1.00
159_I	299_A	0.895	1.00
112_I	212_F	0.891	1.00
80_G	83_Y	0.887	1.00
215_T	366_A	0.887	1.00
163_Q	296_T	0.885	1.00
87_Q	318_D	0.884	1.00
52_P	257_Q	0.884	1.00
140_F	298_L	0.882	1.00
188_A	195_S	0.881	1.00
405_A	409_G	0.880	1.00
371_T	409_G	0.876	1.00
321_F	326_F	0.875	1.00
401_P	404_G	0.875	1.00
246_G	250_I	0.872	1.00
75_R	389_K	0.872	1.00
100_W	321_F	0.868	1.00
337_A	341_I	0.866	1.00
305_H	344_G	0.866	1.00
417_E	423_G	0.862	1.00
80_G	84_T	0.860	1.00
419_S	423_G	0.859	1.00
22_P	154_N	0.857	1.00
254_Y	258_L	0.855	1.00
204_I	410_A	0.853	1.00
330_H	334_R	0.852	1.00
361_L	365_G	0.849	1.00
93_T	431_L	0.849	1.00
271_A	275_E	0.847	1.00
56_A	60_I	0.846	1.00
326_F	338_M	0.844	1.00
17_T	150_K	0.837	1.00
171_L	175_V	0.837	1.00
376_S	380_Q	0.837	1.00
20_L	237_A	0.834	1.00
344_G	348_L	0.832	1.00
354_D	357_M	0.831	1.00
50_H	194_W	0.824	1.00
425_I	428_A	0.821	1.00
401_P	411_L	0.821	1.00
283_K	287_V	0.818	1.00
419_S	422_L	0.817	1.00
74_R	390_T	0.816	1.00
240_L	244_I	0.815	1.00
418_S	423_G	0.813	1.00
53_T	203_M	0.812	1.00
32_Q	35_T	0.811	1.00
117_A	297_V	0.808	1.00
133_F	136_A	0.808	1.00
118_K	130_S	0.807	1.00
205_T	209_I	0.805	1.00
25_M	157_T	0.803	1.00
364_F	423_G	0.801	1.00
215_T	370_F	0.799	1.00
219_G	307_G	0.799	1.00
21_V	157_T	0.798	1.00
373_V	376_S	0.797	1.00
427_A	430_G	0.796	1.00
36_L	252_A	0.796	1.00
175_V	251_F	0.796	1.00
117_A	298_L	0.795	1.00
32_Q	163_Q	0.794	1.00
423_G	427_A	0.793	1.00
141_M	305_H	0.792	1.00
138_V	351_I	0.790	1.00
415_L	420_M	0.788	1.00
63_L	67_L	0.787	1.00
378_I	402_M	0.785	1.00
131_W	351_I	0.779	1.00
86_A	376_S	0.777	1.00
50_H	203_M	0.775	1.00
176_Y	179_F	0.774	1.00
154_N	157_T	0.773	1.00
122_E	130_S	0.772	1.00
115_L	358_A	0.771	1.00
397_Y	402_M	0.771	1.00
107_L	346_I	0.766	1.00
264_S	268_D	0.766	1.00
194_W	203_M	0.766	1.00
64_F	68_S	0.764	1.00
63_L	239_F	0.762	1.00
191_R	194_W	0.762	1.00
179_F	183_G	0.758	1.00
414_N	417_E	0.749	1.00
181_G	184_A	0.749	1.00
235_P	238_I	0.746	1.00
389_K	395_F	0.744	1.00
75_R	385_E	0.741	1.00
229_D	235_P	0.740	1.00
378_I	382_W	0.738	1.00
31_M	241_T	0.737	1.00
200_V	204_I	0.735	1.00
143_A	146_L	0.734	1.00
417_E	424_L	0.733	1.00
112_I	359_T	0.733	1.00
429_I	432_I	0.730	1.00
91_S	438_T	0.727	1.00
387_R	390_T	0.726	1.00
184_A	187_L	0.724	1.00
147_R	151_S	0.724	1.00
432_I	435_A	0.721	1.00
402_M	405_A	0.720	1.00
102_S	106_Y	0.718	1.00
43_V	47_T	0.716	1.00
53_T	56_A	0.716	1.00
377_V	381_F	0.716	1.00
17_T	149_L	0.715	1.00
365_G	369_A	0.714	1.00
400_L	404_G	0.713	1.00
416_E	420_M	0.713	1.00
131_W	134_V	0.713	1.00
188_A	196_G	0.711	1.00
178_V	181_G	0.711	1.00
305_H	309_A	0.709	1.00
145_N	306_A	0.707	1.00
356_V	359_T	0.705	1.00
83_Y	87_Q	0.704	1.00
380_Q	384_R	0.701	1.00
146_L	333_W	0.701	1.00
145_N	340_I	0.701	1.00
271_A	274_P	0.699	1.00
369_A	373_V	0.698	1.00
355_L	359_T	0.694	1.00
382_W	386_K	0.693	1.00
325_F	342_L	0.691	1.00
94_V	372_F	0.690	1.00
24_V	237_A	0.689	1.00
372_F	376_S	0.688	1.00
72_L	85_Y	0.688	1.00
146_L	340_I	0.686	1.00
426_W	434_L	0.686	1.00
386_K	389_K	0.684	1.00
202_P	205_T	0.679	1.00
196_G	199_H	0.678	1.00
397_Y	405_A	0.674	1.00
417_E	430_G	0.674	1.00
124_L	291_I	0.673	1.00
24_V	27_G	0.672	1.00
426_W	429_I	0.671	1.00
312_M	342_L	0.671	1.00
141_M	298_L	0.671	1.00
345_A	348_L	0.669	1.00
265_R	268_D	0.665	1.00
53_T	57_F	0.665	1.00
32_Q	248_I	0.663	1.00
135_V	352_N	0.663	1.00
374_N	377_V	0.662	1.00
153_A	157_T	0.662	1.00
316_G	326_F	0.661	1.00
72_L	377_V	0.661	1.00
244_I	248_I	0.661	1.00
310_R	313_Y	0.660	1.00
309_A	339_N	0.659	1.00
240_L	243_L	0.657	1.00
62_I	217_F	0.657	1.00
139_A	142_T	0.657	1.00
21_V	154_N	0.657	1.00
83_Y	99_G	0.655	1.00
395_F	400_L	0.655	1.00
73_V	234_I	0.653	1.00
178_V	255_F	0.653	1.00
171_L	252_A	0.652	1.00
43_V	210_L	0.652	1.00
377_V	401_P	0.648	1.00
153_A	302_M	0.645	1.00
403_C	406_L	0.643	1.00
14_L	17_T	0.641	1.00
65_T	408_V	0.640	1.00
179_F	187_L	0.638	1.00
395_F	398_L	0.637	1.00
363_N	366_A	0.637	1.00
113_N	301_G	0.635	1.00
378_I	398_L	0.635	1.00
101_S	369_A	0.635	1.00
29_A	160_V	0.634	1.00
180_E	183_G	0.634	1.00
399_F	413_V	0.632	1.00
284_A	287_V	0.631	1.00
215_T	218_D	0.629	1.00
374_N	405_A	0.626	1.00
52_P	56_A	0.626	1.00
190_T	194_W	0.625	1.00
189_S	193_F	0.624	1.00
162_L	292_F	0.620	1.00
366_A	369_A	0.618	1.00
427_A	431_L	0.614	1.00
221_S	238_I	0.613	1.00
118_K	121_F	0.612	1.00
389_K	394_H	0.612	1.00
83_Y	95_G	0.610	1.00
403_C	407_T	0.609	1.00
149_L	223_L	0.609	1.00
109_A	113_N	0.608	1.00
188_A	194_W	0.607	1.00
82_A	222_N	0.606	1.00
225_E	313_Y	0.606	1.00
89_S	379_S	0.606	1.00
52_P	250_I	0.606	1.00
55_Y	213_S	0.606	1.00
137_L	301_G	0.604	1.00
40_F	253_T	0.604	1.00
385_E	388_N	0.603	1.00
120_Y	293_S	0.602	1.00
105_D	366_A	0.601	1.00
421_V	424_L	0.601	1.00
70_G	74_R	0.601	1.00
69_Y	373_V	0.600	1.00
342_L	346_I	0.600	1.00
251_F	255_F	0.599	1.00
124_L	290_L	0.599	1.00
49_G	257_Q	0.598	1.00
332_K	337_A	0.598	1.00
79_A	313_Y	0.597	1.00
433_Y	439_K	0.593	1.00
226_E	336_P	0.592	1.00
308_V	312_M	0.591	1.00
82_A	218_D	0.591	1.00
173_M	281_A	0.591	1.00
291_I	295_I	0.590	1.00
17_T	21_V	0.587	1.00
370_F	374_N	0.587	1.00
151_S	154_N	0.585	1.00
123_A	290_L	0.585	1.00
277_M	285_F	0.585	1.00
409_G	412_W	0.584	1.00
400_L	403_C	0.584	1.00
58_A	214_F	0.584	1.00
252_A	256_L	0.584	1.00
399_F	407_T	0.584	1.00
392_K	395_F	0.584	1.00
51_V	253_T	0.583	1.00
28_L	160_V	0.583	1.00
91_S	95_G	0.582	1.00
111_M	350_A	0.582	1.00
66_A	217_F	0.581	1.00
336_P	339_N	0.581	1.00
140_F	144_F	0.581	1.00
178_V	259_Y	0.577	1.00
388_N	393_D	0.577	1.00
106_Y	304_A	0.577	1.00
108_F	361_L	0.577	1.00
425_I	432_I	0.576	1.00
296_T	299_A	0.576	1.00
30_Y	304_A	0.575	1.00
21_V	24_V	0.575	1.00
419_S	426_W	0.574	1.00
183_G	187_L	0.573	1.00
90_I	376_S	0.573	1.00
148_S	151_S	0.572	1.00
109_A	112_I	0.571	1.00
116_L	120_Y	0.571	1.00
406_L	409_G	0.569	1.00
152_V	306_A	0.568	1.00
128_I	133_F	0.568	1.00
178_V	182_E	0.568	1.00
234_I	238_I	0.567	1.00
73_V	221_S	0.566	1.00
191_R	196_G	0.566	1.00
121_F	137_L	0.565	1.00
255_F	258_L	0.562	1.00
114_I	118_K	0.562	1.00
66_A	70_G	0.562	1.00
400_L	408_V	0.561	1.00
310_R	336_P	0.561	1.00
348_L	351_I	0.560	1.00
244_I	247_M	0.560	1.00
64_F	400_L	0.559	1.00
260_F	275_E	0.558	1.00
139_A	341_I	0.557	1.00
326_F	339_N	0.557	1.00
407_T	410_A	0.557	1.00
426_W	433_Y	0.556	1.00
252_A	273_Q	0.555	1.00
322_P	325_F	0.555	1.00
256_L	273_Q	0.555	1.00
72_L	89_S	0.554	1.00
111_M	358_A	0.553	1.00
433_Y	438_T	0.552	1.00
70_G	238_I	0.552	1.00
376_S	379_S	0.551	1.00
136_A	139_A	0.550	1.00
305_H	340_I	0.549	1.00
380_Q	385_E	0.549	1.00
378_I	401_P	0.548	1.00
337_A	340_I	0.546	1.00
397_Y	412_W	0.545	1.00
52_P	55_Y	0.544	1.00
188_A	193_F	0.544	1.00
227_T	234_I	0.544	1.00
30_Y	303_A	0.543	1.00
156_N	299_A	0.543	1.00
187_L	190_T	0.541	1.00
230_A	233_V	0.541	1.00
142_T	305_H	0.541	1.00
138_V	348_L	0.540	1.00
162_L	166_L	0.540	1.00
151_S	155_F	0.540	1.00
113_N	116_L	0.539	1.00
424_L	427_A	0.539	1.00
157_T	161_V	0.539	1.00
227_T	237_A	0.538	1.00
109_A	362_I	0.538	1.00
33_P	249_F	0.537	1.00
405_A	412_W	0.537	1.00
381_F	384_R	0.536	1.00
405_A	413_V	0.533	1.00
264_S	267_K	0.532	1.00
383_I	387_R	0.532	1.00
231_E	388_N	0.531	1.00
105_D	365_G	0.531	1.00
404_G	412_W	0.531	1.00
30_Y	219_G	0.530	1.00
158_V	161_V	0.530	1.00
57_F	207_A	0.529	1.00
58_A	211_C	0.528	1.00
431_L	434_L	0.528	1.00
65_T	218_D	0.527	1.00
349_L	352_N	0.527	1.00
89_S	380_Q	0.526	1.00
415_L	419_S	0.526	1.00
107_L	343_V	0.525	1.00
400_L	407_T	0.524	1.00
397_Y	411_L	0.524	1.00
417_E	434_L	0.524	1.00
36_L	167_I	0.524	1.00
14_L	79_A	0.523	1.00
310_R	329_V	0.523	1.00
382_W	398_L	0.521	1.00
222_N	307_G	0.520	1.00
226_E	329_V	0.520	1.00
23_V	233_V	0.519	1.00
28_L	31_M	0.519	1.00
414_N	420_M	0.519	1.00
55_Y	253_T	0.518	1.00
27_G	31_M	0.515	1.00
13_E	16_K	0.515	1.00
173_M	282_G	0.514	1.00
37_F	167_I	0.514	1.00
93_T	434_L	0.513	1.00
429_I	437_V	0.513	1.00
220_I	234_I	0.513	1.00
407_T	412_W	0.511	1.00
42_I	356_V	0.510	1.00
86_A	95_G	0.510	1.00
402_M	412_W	0.509	1.00
231_E	236_R	0.508	1.00
71_K	75_R	0.505	1.00
33_P	37_F	0.503	1.00
81_S	221_S	0.503	1.00
369_A	376_S	0.503	1.00
265_R	269_P	0.503	1.00
230_A	234_I	0.502	1.00
32_Q	37_F	0.502	1.00
213_S	249_F	0.500	1.00
201_I	204_I	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3l1lA	2	0.9093	100	0.284	Contact Map
3giaA	1	0.9314	100	0.362	Contact Map
4djkA	2	0.885	100	0.366	Contact Map
3dh4A	3	0.927	99	0.852	Contact Map
2xq2A	2	0.9314	98.9	0.858	Contact Map
2jlnA	1	0.9093	98.8	0.861	Contact Map
4wgvA	2	0.8053	98.1	0.888	Contact Map
2a65A	2	0.9137	97.3	0.906	Contact Map
4xp4A	1	0.9314	96.7	0.913	Contact Map
4us3A	1	0.8695	96	0.919	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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