OMPR - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

OMPR - Transcriptional regulatory protein OmpR

UniProt:	P0AA16	Sequences: MQENYKILVVDDDMRLRALLERYLTEQGFQVRSVANAEQMDRLLTRESFHLMVLDLMLPGEDGLSICRRLRSQSNPMPIIMVTAKGEEVDRIVGLEIGADDYIPKPFNPRELLARIRAVLRRQANELPGAPSQEEAVIAFGKFKLNLGTREMFREDEPMPLTSGEFAVLKALVSHPREPLSRDKLMNLARGREYSAMERSIDVQISRLRRMVEEDPAHPRYIQTVWGLGYVFVPDGSKA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10672
Length:	239 (207)
Sequences:	74368 (52195)
Seq/√Len:	3627.8

ECOLI - OMPR PHOP CUSR CREB YEDW RSTA ARCA BAER QSEB BASR PHOB KDPE CPXR DPIA TORR FIMZ NARP UVRY YGEK EVGA YHJB NARL YJJQ RCSB DCUR BGLJ RSSB TORS CSGD BARA RCSA UHPA RCSC ARCB CHEB YPDB YEHT EVGS ATOC NTRC GLRR ZRAR RCSD
BACSU - PHOP YVRH YYCF YVCP YKOG YCBL YXDJ RESD YCLJ CSSR BCER YRKP DCTR CITT YXJL YFIK DEGU MALR CMPA LIAR YVFU YHCZ YBDJ YDFI DESR YESN GLNL LYTT NATR SP0A CHEB CHEV
HALSA - Q9HR09 CHEB Q9HRE5 BAT Q9HNM3 O51970 Q9HP91

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
17_R	33_S	3.726	1.00
17_R	35_A	3.250	1.00
21_E	33_S	3.196	1.00
10_V	40_M	2.733	1.00
41_D	69_R	2.669	1.00
38_E	60_G	2.548	1.00
32_R	49_F	2.399	1.00
37_A	61_E	2.386	1.00
61_E	69_R	2.340	1.00
36_N	60_G	2.337	1.00
45_T	73_Q	2.301	1.00
6_K	32_R	2.175	1.00
6_K	30_Q	2.116	1.00
23_Y	109_P	2.084	1.00
21_E	25_T	2.079	1.00
27_Q	113_L	2.058	1.00
34_V	43_L	2.034	1.00
57_M	85_K	1.895	1.00
35_A	39_Q	1.860	1.00
91_R	111_E	1.846	1.00
54_L	66_I	1.795	1.00
32_R	43_L	1.770	1.00
36_N	39_Q	1.766	1.00
199_R	202_D	1.754	1.00
164_G	167_A	1.743	1.00
81_M	94_G	1.740	1.00
71_R	100_D	1.717	1.00
67_C	79_I	1.691	1.00
8_L	34_V	1.681	1.00
43_L	47_E	1.635	1.00
69_R	73_Q	1.634	1.00
88_E	108_N	1.630	1.00
182_R	202_D	1.613	1.00
32_R	47_E	1.603	1.00
5_Y	120_L	1.575	1.00
170_K	174_S	1.565	1.00
61_E	65_S	1.560	1.00
81_M	99_A	1.558	1.00
171_A	188_L	1.545	1.00
37_A	66_I	1.537	1.00
180_L	188_L	1.524	1.00
24_L	116_I	1.514	1.00
85_K	90_D	1.511	1.00
68_R	97_I	1.507	1.00
101_D	115_R	1.498	1.00
43_L	46_R	1.491	1.00
62_D	65_S	1.489	1.00
181_S	184_K	1.454	1.00
44_L	70_L	1.438	1.00
52_M	77_M	1.437	1.00
204_Q	207_R	1.433	1.00
139_A	144_K	1.429	1.00
69_R	72_S	1.421	1.00
142_K	155_E	1.412	1.00
38_E	61_E	1.401	1.00
14_M	35_A	1.374	1.00
80_I	119_V	1.350	1.00
51_L	116_I	1.350	1.00
67_C	81_M	1.337	1.00
65_S	68_R	1.323	1.00
41_D	66_I	1.308	1.00
165_E	211_M	1.292	1.00
29_F	117_R	1.255	1.00
6_K	47_E	1.249	1.00
137_V	144_K	1.242	1.00
56_L	64_L	1.241	1.00
100_D	122_R	1.228	1.00
43_L	49_F	1.227	1.00
10_V	58_L	1.220	1.00
11_D	17_R	1.213	1.00
42_R	46_R	1.209	1.00
41_D	61_E	1.200	1.00
64_L	94_G	1.194	1.00
54_L	67_C	1.190	1.00
171_A	175_H	1.178	1.00
39_Q	42_R	1.174	1.00
39_Q	43_L	1.169	1.00
56_L	81_M	1.161	1.00
113_L	117_R	1.161	1.00
184_K	188_L	1.159	1.00
34_V	40_M	1.157	1.00
28_G	117_R	1.154	1.00
12_D	55_D	1.154	1.00
100_D	119_V	1.151	1.00
8_L	49_F	1.147	1.00
144_K	153_F	1.144	1.00
87_E	90_D	1.143	1.00
88_E	92_I	1.135	1.00
166_F	170_K	1.126	1.00
151_E	158_P	1.118	1.00
146_N	149_T	1.116	1.00
64_L	93_V	1.115	1.00
27_Q	117_R	1.104	1.00
38_E	42_R	1.102	1.00
93_V	97_I	1.093	1.00
8_L	40_M	1.091	1.00
183_D	198_E	1.087	1.00
171_A	180_L	1.079	1.00
7_I	29_F	1.073	1.00
74_S	77_M	1.073	1.00
51_L	120_L	1.060	1.00
203_V	206_S	1.054	1.00
5_Y	29_F	1.051	1.00
96_E	117_R	1.046	1.00
114_A	118_A	1.032	1.00
8_L	43_L	1.024	1.00
111_E	114_A	1.022	1.00
34_V	39_Q	1.021	1.00
145_L	173_V	1.017	1.00
147_L	170_K	1.015	1.00
136_A	148_G	1.013	1.00
89_V	93_V	1.011	1.00
163_S	167_A	0.998	1.00
199_R	203_V	0.996	1.00
21_E	31_V	0.989	1.00
92_I	96_E	0.981	1.00
41_D	45_T	0.979	1.00
40_M	66_I	0.976	1.00
167_A	170_K	0.970	1.00
18_A	33_S	0.965	1.00
214_E	224_T	0.963	1.00
91_R	104_P	0.958	1.00
15_R	19_L	0.958	1.00
153_F	158_P	0.956	1.00
68_R	93_V	0.954	1.00
40_M	44_L	0.946	1.00
52_M	70_L	0.944	1.00
9_V	20_L	0.942	1.00
10_V	34_V	0.940	1.00
14_M	18_A	0.933	1.00
145_L	166_F	0.930	1.00
54_L	79_I	0.927	1.00
56_L	62_D	0.925	1.00
64_L	97_I	0.922	1.00
164_G	190_R	0.915	1.00
20_L	82_V	0.915	1.00
180_L	184_K	0.906	1.00
171_A	185_L	0.904	1.00
10_V	52_M	0.898	1.00
200_S	204_Q	0.898	1.00
8_L	44_L	0.883	1.00
119_V	122_R	0.881	1.00
44_L	74_S	0.878	1.00
6_K	50_H	0.873	1.00
215_D	218_H	0.868	1.00
65_S	69_R	0.865	1.00
14_M	17_R	0.861	1.00
54_L	81_M	0.860	1.00
198_E	202_D	0.856	1.00
67_C	97_I	0.851	1.00
29_F	113_L	0.850	1.00
42_R	45_T	0.850	1.00
199_R	206_S	0.843	1.00
214_E	220_R	0.842	1.00
53_V	112_L	0.837	1.00
139_A	142_K	0.833	1.00
9_V	31_V	0.832	1.00
93_V	96_E	0.832	1.00
5_Y	124_A	0.830	1.00
86_G	104_P	0.829	1.00
67_C	99_A	0.825	1.00
88_E	91_R	0.825	1.00
22_R	26_E	0.822	1.00
118_A	123_Q	0.822	1.00
111_E	115_R	0.819	1.00
137_V	146_N	0.816	1.00
48_S	74_S	0.808	1.00
78_P	100_D	0.808	1.00
205_I	209_R	0.804	1.00
56_L	90_D	0.804	1.00
53_V	82_V	0.802	1.00
150_R	167_A	0.794	1.00
207_R	210_R	0.794	1.00
80_I	115_R	0.793	1.00
18_A	21_E	0.793	1.00
66_I	70_L	0.792	1.00
58_L	66_I	0.782	1.00
92_I	110_R	0.776	1.00
52_M	79_I	0.775	1.00
182_R	198_E	0.774	1.00
68_R	72_S	0.773	1.00
6_K	49_F	0.767	1.00
162_T	211_M	0.762	1.00
109_P	113_L	0.762	1.00
61_E	66_I	0.759	1.00
183_D	187_N	0.759	1.00
20_L	112_L	0.759	1.00
16_L	107_F	0.759	1.00
70_L	75_N	0.757	1.00
82_V	107_F	0.757	1.00
56_L	85_K	0.754	1.00
171_A	174_S	0.754	1.00
118_A	121_R	0.748	1.00
90_D	93_V	0.747	1.00
44_L	77_M	0.746	1.00
89_V	110_R	0.744	1.00
206_S	210_R	0.744	1.00
213_E	216_P	0.742	1.00
44_L	49_F	0.736	1.00
168_V	172_L	0.733	1.00
203_V	207_R	0.733	1.00
108_N	111_E	0.727	1.00
53_V	116_I	0.726	1.00
37_A	41_D	0.722	1.00
184_K	187_N	0.718	1.00
10_V	66_I	0.718	1.00
23_Y	113_L	0.718	1.00
220_R	223_Q	0.718	1.00
57_M	84_A	0.717	1.00
18_A	22_R	0.701	1.00
209_R	214_E	0.696	1.00
95_L	115_R	0.695	1.00
120_L	123_Q	0.689	1.00
37_A	60_G	0.680	1.00
41_D	44_L	0.678	1.00
213_E	220_R	0.673	1.00
167_A	171_A	0.667	1.00
215_D	220_R	0.664	1.00
19_L	23_Y	0.663	1.00
80_I	101_D	0.661	1.00
45_T	74_S	0.661	1.00
107_F	112_L	0.660	1.00
78_P	120_L	0.660	1.00
44_L	52_M	0.659	1.00
96_E	114_A	0.658	1.00
143_F	154_R	0.656	1.00
187_N	190_R	0.653	1.00
55_D	105_K	0.653	1.00
94_G	99_A	0.648	1.00
7_I	51_L	0.647	1.00
123_Q	127_L	0.647	1.00
196_A	201_I	0.647	1.00
9_V	33_S	0.646	1.00
76_P	125_N	0.643	1.00
11_D	58_L	0.641	1.00
17_R	21_E	0.641	1.00
45_T	69_R	0.640	1.00
88_E	110_R	0.640	1.00
24_L	29_F	0.639	1.00
145_L	152_M	0.637	1.00
25_T	31_V	0.637	1.00
7_I	24_L	0.636	1.00
153_F	156_D	0.635	1.00
41_D	73_Q	0.631	1.00
174_S	180_L	0.630	1.00
150_R	166_F	0.629	1.00
174_S	188_L	0.624	1.00
9_V	21_E	0.623	1.00
172_L	205_I	0.623	1.00
110_R	114_A	0.613	1.00
91_R	108_N	0.611	1.00
147_L	174_S	0.607	1.00
154_R	157_E	0.607	1.00
145_L	170_K	0.607	1.00
13_D	84_A	0.606	1.00
76_P	126_E	0.606	1.00
37_A	58_L	0.606	1.00
164_G	204_Q	0.605	1.00
107_F	111_E	0.600	1.00
71_R	78_P	0.599	1.00
64_L	90_D	0.599	1.00
202_D	205_I	0.597	1.00
5_Y	50_H	0.594	1.00
142_K	154_R	0.587	1.00
53_V	80_I	0.582	1.00
162_T	165_E	0.578	1.00
71_R	77_M	0.577	1.00
220_R	224_T	0.576	1.00
217_A	220_R	0.576	1.00
205_I	217_A	0.572	1.00
115_R	119_V	0.569	1.00
92_I	95_L	0.566	1.00
70_L	79_I	0.562	1.00
101_D	118_A	0.562	1.00
154_R	215_D	0.561	1.00
83_T	105_K	0.561	1.00
25_T	30_Q	0.560	1.00
12_D	83_T	0.559	1.00
114_A	117_R	0.558	1.00
140_F	144_K	0.557	1.00
23_Y	27_Q	0.557	1.00
13_D	16_L	0.555	1.00
117_R	121_R	0.553	1.00
56_L	94_G	0.550	1.00
197_M	200_S	0.547	1.00
39_Q	60_G	0.546	1.00
216_P	220_R	0.546	1.00
136_A	147_L	0.542	1.00
86_G	106_P	0.538	1.00
54_L	58_L	0.535	1.00
83_T	102_Y	0.534	1.00
146_N	151_E	0.534	1.00
186_M	190_R	0.532	1.00
19_L	22_R	0.530	1.00
154_R	213_E	0.526	1.00
8_L	47_E	0.524	1.00
154_R	214_E	0.524	1.00
78_P	122_R	0.523	1.00
89_V	92_I	0.523	1.00
138_I	147_L	0.519	1.00
67_C	71_R	0.517	1.00
83_T	91_R	0.516	1.00
51_L	119_V	0.507	1.00
54_L	70_L	0.507	1.00
16_L	19_L	0.506	1.00
94_G	102_Y	0.504	1.00
136_A	140_F	0.503	1.00
78_P	123_Q	0.503	1.00
36_N	58_L	0.503	1.00
70_L	77_M	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1ys7A	2	0.9456	100	0.201	Contact Map
3r0jA	2	0.9331	100	0.201	Contact Map
2gwrA	1	0.9372	100	0.202	Contact Map
1kgsA	1	0.9163	100	0.22	Contact Map
4b09A	2	0.8996	100	0.221	Contact Map
2oqrA	2	0.9456	100	0.222	Contact Map
4kfcA	2	0.9372	100	0.229	Contact Map
2hqrA	2	0.9205	100	0.249	Contact Map
1p2fA	1	0.9079	100	0.253	Contact Map
3q9sA	1	0.8787	100	0.262	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0093 seconds.