GREMLIN Database
GLNB - Nitrogen regulatory protein P-II 1
UniProt: P0A9Z1 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10384
Length: 112 (112)
Sequences: 2943 (1586)
Seq/√Len: 149.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
98_R107_E4.4341.00
64_V96_V3.6651.00
98_R108_D3.5941.00
65_V73_C3.0461.00
66_P109_D2.6261.00
12_K15_D2.4971.00
69_I72_T2.3931.00
16_V81_A2.2581.00
78_I82_Q2.2451.00
6_A77_I2.2281.00
23_V76_T2.1811.00
29_T33_V2.1651.00
5_D94_F1.9601.00
76_T80_T1.9341.00
75_D79_R1.8991.00
74_V93_V1.8341.00
66_P69_I1.7931.00
3_K64_V1.6941.00
71_D75_D1.6821.00
8_I16_V1.6641.00
13_L30_V1.5571.00
31_T62_E1.4971.00
16_V61_I1.3941.00
72_T76_T1.3701.00
31_T60_K1.3471.00
4_I73_C1.3441.00
67_D109_D1.3091.00
74_V91_I1.2691.00
2_K67_D1.2631.00
75_D78_I1.2541.00
78_I91_I1.2281.00
3_K94_F1.2131.00
18_E22_E1.2121.00
78_I107_E1.2031.00
5_D60_K1.1701.00
4_I65_V1.1641.00
72_T79_R1.1611.00
8_I61_I1.1611.00
19_A22_E1.1581.00
101_R106_E1.1461.00
7_I29_T1.1351.00
19_A79_R1.1200.99
65_V70_V1.1150.99
71_D107_E1.1080.99
82_Q105_G1.1050.99
30_V55_F1.1040.99
2_K95_D1.1010.99
64_V92_F1.0990.99
8_I13_L1.0980.99
17_R28_M1.0940.99
9_K86_I1.0940.99
2_K70_V1.0880.99
39_Q56_L1.0870.99
92_F102_I1.0740.99
2_K93_V1.0580.99
71_D98_R1.0570.99
70_V74_V1.0570.99
5_D64_V1.0430.99
78_I100_I1.0340.99
2_K97_A1.0290.99
39_Q58_K1.0200.99
103_R106_E1.0110.99
19_A80_T1.0020.99
13_L59_V0.9840.99
84_G88_D0.9740.99
20_L63_I0.9670.98
72_T75_D0.9470.98
21_A36_F0.9390.98
9_K33_V0.9360.98
42_H54_D0.9330.98
4_I77_I0.9270.98
36_F54_D0.9050.98
25_I63_I0.9040.98
36_F42_H0.8980.97
63_I73_C0.8960.97
23_V72_T0.8950.97
99_V111_A0.8850.97
83_T88_D0.8660.97
19_A76_T0.8560.97
69_I73_C0.8450.96
27_G36_F0.8150.96
16_V80_T0.7880.95
60_K92_F0.7810.94
43_T50_E0.7790.94
100_I107_E0.7750.94
46_Y49_A0.7710.94
7_I92_F0.7670.94
74_V100_I0.7510.93
13_L54_D0.7510.93
41_G58_K0.7450.93
42_H49_A0.7380.93
36_F55_F0.7330.92
11_F15_D0.7320.92
6_A81_A0.7310.92
47_R51_Y0.7300.92
20_L77_I0.7270.92
45_L49_A0.7260.92
42_H45_L0.7210.92
28_M61_I0.7200.92
6_A63_I0.7100.91
3_K96_V0.6940.90
42_H50_E0.6910.90
25_I73_C0.6800.89
8_I77_I0.6720.89
5_D62_E0.6690.88
21_A40_K0.6660.88
48_G51_Y0.6650.88
13_L55_F0.6610.88
37_G90_K0.6560.87
11_F56_L0.6530.87
92_F99_V0.6510.87
70_V95_D0.6500.87
20_L73_C0.6490.87
66_P73_C0.6480.87
45_L85_K0.6480.87
33_V60_K0.6440.86
91_I100_I0.6280.85
8_I12_K0.6270.85
67_D70_V0.6270.85
15_D80_T0.6260.85
45_L50_E0.6130.84
43_T52_M0.6080.83
1_M67_D0.6040.83
30_V61_I0.5930.82
41_G44_E0.5910.81
3_K92_F0.5910.81
5_D99_V0.5910.81
32_E59_V0.5890.81
34_K46_Y0.5880.81
71_D78_I0.5860.81
79_R82_Q0.5850.81
17_R21_A0.5820.80
20_L61_I0.5790.80
17_R54_D0.5770.80
27_G99_V0.5730.79
22_E79_R0.5710.79
38_R44_E0.5700.79
44_E49_A0.5670.79
57_P85_K0.5620.78
11_F55_F0.5610.78
25_I42_H0.5600.78
20_L72_T0.5520.77
36_F102_I0.5500.77
27_G56_L0.5470.76
45_L54_D0.5460.76
28_M62_E0.5420.75
76_T79_R0.5400.75
39_Q86_I0.5380.75
11_F32_E0.5350.75
70_V98_R0.5340.74
28_M52_M0.5320.74
38_R102_I0.5280.74
9_K82_Q0.5280.74
48_G62_E0.5270.73
11_F49_A0.5230.73
25_I76_T0.5210.73
77_I81_A0.5180.72
74_V78_I0.5180.72
13_L61_I0.5150.72
70_V93_V0.5150.72
13_L52_M0.5140.72
42_H85_K0.5130.71
53_V112_I0.5130.71
2_K8_I0.5110.71
20_L23_V0.5040.70
100_I106_E0.5000.70
85_K102_I0.5000.70
13_L28_M0.5000.70
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4ozjA 3 0.875 100 0.18 Contact Map
3t9zA 3 0.875 100 0.191 Contact Map
2o66A 5 0.8661 100 0.193 Contact Map
3ncqA 4 1 100 0.199 Contact Map
1hwuA 6 0.9554 100 0.209 Contact Map
1vfjA 3 1 100 0.212 Contact Map
4r25A 3 1 100 0.214 Contact Map
3bzqA 3 0.8661 100 0.214 Contact Map
3l7pA 4 0.8125 100 0.216 Contact Map
2ns1B 3 1 100 0.225 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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