GREMLIN Database
CSPC - Cold shock-like protein CspC
UniProt: P0A9Y6 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12204
Length: 69 (63)
Sequences: 4119 (1631)
Seq/√Len: 205.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
31_V66_V3.6991.00
55_Q64_V3.4721.00
53_E65_N2.6771.00
51_E67_T2.3081.00
13_E45_A2.2571.00
7_Q49_N2.1131.00
23_A49_N2.0311.00
37_Q67_T1.9601.00
4_I22_P1.9511.00
5_K51_E1.9291.00
22_P27_K1.6951.00
5_K49_N1.6441.00
45_A48_Q1.6221.00
35_A64_V1.6111.00
56_D61_P1.5681.00
37_Q65_N1.4821.00
31_V44_L1.4661.00
57_G62_A1.4371.00
13_E41_F1.4241.00
22_P52_F1.3141.00
13_E43_T1.3101.00
57_G61_P1.2291.00
22_P25_G1.2121.00
29_V54_I1.1971.00
36_I41_F1.1231.00
27_K61_P1.1041.00
36_I42_K1.1031.00
54_I61_P1.0801.00
44_L50_V1.0471.00
7_Q21_T1.0371.00
5_K23_A1.0101.00
35_A55_Q0.9961.00
20_I52_F0.9871.00
33_F42_K0.9811.00
57_G60_G0.9761.00
6_G20_I0.9721.00
9_K28_D0.9560.99
9_K15_K0.9060.99
20_I50_V0.8890.99
6_G63_A0.8680.99
11_F33_F0.8610.99
4_I24_D0.8540.99
36_I39_N0.8320.99
10_W15_K0.8280.99
35_A65_N0.8250.98
33_F36_I0.7690.98
55_Q62_A0.7680.98
14_S48_Q0.7600.97
11_F15_K0.7420.97
20_I63_A0.7410.97
52_F63_A0.7250.97
33_F59_K0.6940.96
36_I66_V0.6670.95
4_I52_F0.6590.94
38_G42_K0.6520.94
12_N30_F0.6510.94
22_P54_I0.6390.93
7_Q23_A0.6370.93
15_K28_D0.6360.93
11_F16_G0.6310.93
20_I31_V0.6250.92
18_G31_V0.6170.92
19_F32_H0.6120.92
16_G28_D0.6110.92
29_V55_Q0.6110.92
29_V35_A0.5990.91
10_W31_V0.5950.90
21_T47_G0.5850.90
4_I67_T0.5820.89
9_K16_G0.5800.89
14_S62_A0.5780.89
58_Q61_P0.5640.88
10_W28_D0.5630.88
8_V44_L0.5550.87
46_E62_A0.5540.87
11_F41_F0.5510.87
21_T29_V0.5500.87
43_T48_Q0.5460.86
4_I13_E0.5460.86
29_V63_A0.5440.86
4_I54_I0.5410.86
38_G41_F0.5280.84
34_S59_K0.5250.84
27_K56_D0.5240.84
30_F48_Q0.5190.83
27_K65_N0.5180.83
12_N17_F0.5170.83
16_G60_G0.5130.83
15_K40_G0.5090.82
33_F66_V0.5080.82
33_F41_F0.5050.82
10_W16_G0.5050.82
56_D64_V0.5020.81
33_F37_Q0.5000.81
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3i2zB 2 1 99.7 0.137 Contact Map
2lssA 1 1 99.7 0.175 Contact Map
3camA 2 0.971 99.7 0.177 Contact Map
2mqhA 1 0.971 99.7 0.187 Contact Map
1h95A 1 1 99.7 0.19 Contact Map
3uljA 3 1 99.7 0.191 Contact Map
1c9oA 2 0.9565 99.7 0.201 Contact Map
1g6pA 1 0.942 99.7 0.202 Contact Map
3ts2A 1 1 99.7 0.205 Contact Map
2lxjA 1 0.9565 99.6 0.208 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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