ARCA - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

ARCA - Aerobic respiration control protein ArcA

UniProt:	P0A9Q1	Sequences: MQTPHILIVEDELVTRNTLKSIFEAEGYDVFEATDGAEMHQILSEYDINLVIMDINLPGKNGLLLARELREQANVALMFLTGRDNEVDKILGLEIGADDYITKPFNPRELTIRARNLLSRTMNLGTVSEERRSVESYKFNGWELDINSRSLIGPDGEQYKLPRSEFRAMLHFCENPGKIQSRAELLKKMTGRELKPHDRTVDVTIRRIRKHFESTPDTPEIIATIHGEGYRFCGDLED	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10061
Length:	238 (209)
Sequences:	77258 (55545)
Seq/√Len:	3842.1

ECOLI - ARCA CREB CPXR KDPE RSTA YEDW BAER PHOP TORR OMPR CUSR PHOB BASR QSEB FIMZ DPIA YGEK UVRY DCUR RCSB YHJB NARP EVGA NARL YJJQ BGLJ UHPA CHEB RCSA CSGD BARA RSSB YEHT RCSC ARCB TORS YPDB NTRC EVGS GLRR ATOC ZRAR RCSD
BACSU - YVRH YKOG RESD YCBL YYCF YVCP YXDJ YCLJ YRKP BCER CSSR PHOP CITT YBDJ DEGU YFIK DCTR MALR YXJL CMPA LIAR YVFU YDFI DESR YHCZ GLNL SP0A YESN CHEB LYTT NATR CHEV SP0F
HALSA - CHEB Q9HR09 Q9HNM3 Q9HRE5 BAT O51970 Q9HP91

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
16_R	32_E	3.775	1.00
16_R	34_T	3.317	1.00
20_K	32_E	3.286	1.00
9_V	39_M	2.815	1.00
40_H	68_E	2.769	1.00
37_A	59_G	2.579	1.00
31_F	48_I	2.470	1.00
44_S	72_Q	2.398	1.00
36_G	60_K	2.389	1.00
60_K	68_E	2.388	1.00
35_D	59_G	2.330	1.00
5_H	31_F	2.216	1.00
5_H	29_D	2.087	1.00
33_A	42_I	2.079	1.00
20_K	24_E	2.060	1.00
26_E	111_T	2.045	1.00
22_I	107_P	2.043	1.00
56_N	83_R	1.926	1.00
89_K	109_E	1.913	1.00
34_T	38_E	1.894	1.00
53_M	65_L	1.882	1.00
199_R	202_D	1.845	1.00
66_A	77_L	1.827	1.00
31_F	42_I	1.800	1.00
35_D	38_E	1.776	1.00
79_F	92_G	1.776	1.00
7_L	33_A	1.752	1.00
164_S	167_R	1.736	1.00
68_E	72_Q	1.723	1.00
70_R	98_D	1.684	1.00
79_F	97_A	1.661	1.00
42_I	46_Y	1.656	1.00
86_E	106_N	1.639	1.00
31_F	46_Y	1.622	1.00
4_P	118_L	1.580	1.00
67_R	95_I	1.580	1.00
36_G	65_L	1.571	1.00
99_D	113_R	1.570	1.00
60_K	64_L	1.566	1.00
61_N	64_L	1.559	1.00
43_L	69_L	1.525	1.00
42_I	45_E	1.522	1.00
170_L	174_E	1.519	1.00
182_R	202_D	1.502	1.00
68_E	71_E	1.489	1.00
83_R	88_D	1.480	1.00
171_H	188_K	1.472	1.00
204_T	207_R	1.471	1.00
23_F	114_A	1.461	1.00
51_V	75_V	1.419	1.00
37_A	60_K	1.417	1.00
66_A	79_F	1.414	1.00
64_L	67_R	1.380	1.00
40_H	65_L	1.364	1.00
98_D	120_R	1.341	1.00
50_L	114_A	1.340	1.00
138_K	143_E	1.330	1.00
78_M	117_L	1.325	1.00
98_D	117_L	1.317	1.00
13_L	34_T	1.313	1.00
141_G	155_D	1.299	1.00
42_I	48_I	1.295	1.00
55_I	63_L	1.276	1.00
41_Q	45_E	1.257	1.00
10_E	16_R	1.243	1.00
53_M	66_A	1.234	1.00
11_D	54_D	1.228	1.00
171_H	175_N	1.227	1.00
9_V	57_L	1.221	1.00
40_H	60_K	1.209	1.00
5_H	46_Y	1.197	1.00
38_E	41_Q	1.196	1.00
55_I	79_F	1.196	1.00
28_Y	115_R	1.185	1.00
33_A	39_M	1.183	1.00
7_L	48_I	1.182	1.00
63_L	92_G	1.176	1.00
38_E	42_I	1.166	1.00
111_T	115_R	1.161	1.00
184_E	188_K	1.160	1.00
37_A	41_Q	1.158	1.00
145_D	148_S	1.157	1.00
181_S	184_E	1.156	1.00
63_L	91_L	1.155	1.00
85_N	88_D	1.141	1.00
150_S	158_Q	1.139	1.00
7_L	39_M	1.136	1.00
91_L	95_I	1.133	1.00
205_I	209_R	1.119	1.00
200_T	204_T	1.117	1.00
176_P	188_K	1.115	1.00
86_E	90_I	1.109	1.00
150_S	153_G	1.109	1.00
26_E	115_R	1.095	1.00
143_E	153_G	1.092	1.00
6_I	28_Y	1.083	1.00
199_R	203_V	1.073	1.00
39_M	65_L	1.071	1.00
27_G	115_R	1.071	1.00
7_L	42_I	1.070	1.00
94_E	115_R	1.062	1.00
67_R	91_L	1.057	1.00
112_I	116_N	1.055	1.00
40_H	44_S	1.044	1.00
166_F	170_L	1.039	1.00
109_E	112_I	1.036	1.00
176_P	180_Q	1.030	1.00
165_E	211_H	1.027	1.00
17_N	32_E	1.027	1.00
203_V	206_R	1.019	1.00
33_A	38_E	1.016	1.00
90_I	94_E	1.007	1.00
87_V	91_L	0.998	1.00
50_L	118_L	0.986	1.00
39_M	43_L	0.985	1.00
89_K	102_T	0.982	1.00
20_K	30_V	0.981	1.00
167_R	170_L	0.976	1.00
8_I	19_L	0.969	1.00
164_S	190_T	0.963	1.00
51_V	69_L	0.960	1.00
14_V	18_T	0.960	1.00
146_I	170_L	0.960	1.00
7_L	43_L	0.959	1.00
13_L	17_N	0.958	1.00
4_P	28_Y	0.955	1.00
63_L	95_I	0.955	1.00
144_L	173_C	0.954	1.00
86_E	89_K	0.953	1.00
183_A	198_D	0.953	1.00
53_M	77_L	0.945	1.00
55_I	61_N	0.941	1.00
9_V	33_A	0.923	1.00
41_Q	44_S	0.916	1.00
66_A	95_I	0.915	1.00
19_L	80_L	0.915	1.00
9_V	51_V	0.913	1.00
53_M	79_F	0.912	1.00
64_L	68_E	0.912	1.00
153_G	158_Q	0.887	1.00
51_V	77_L	0.884	1.00
4_P	122_M	0.884	1.00
215_T	218_T	0.878	1.00
91_L	94_E	0.871	1.00
66_A	97_A	0.870	1.00
8_I	30_V	0.868	1.00
144_L	166_F	0.868	1.00
207_R	210_K	0.868	1.00
76_A	98_D	0.863	1.00
17_N	20_K	0.859	1.00
13_L	16_R	0.857	1.00
117_L	120_R	0.855	1.00
163_R	167_R	0.851	1.00
216_P	219_P	0.851	1.00
55_I	88_D	0.849	1.00
171_H	180_Q	0.847	1.00
28_Y	111_T	0.847	1.00
84_D	102_T	0.845	1.00
21_S	25_A	0.844	1.00
5_H	49_N	0.844	1.00
52_I	110_L	0.843	1.00
109_E	113_R	0.839	1.00
65_L	69_L	0.838	1.00
67_R	71_E	0.838	1.00
171_H	185_L	0.832	1.00
78_M	113_R	0.827	1.00
180_Q	184_E	0.818	1.00
198_D	202_D	0.808	1.00
214_S	224_T	0.807	1.00
5_H	48_I	0.801	1.00
57_L	65_L	0.801	1.00
43_L	75_V	0.797	1.00
199_R	206_R	0.796	1.00
60_K	65_L	0.794	1.00
107_P	111_T	0.792	1.00
90_I	108_R	0.790	1.00
52_I	80_L	0.787	1.00
43_L	48_I	0.780	1.00
52_I	114_A	0.776	1.00
15_T	105_F	0.774	1.00
214_S	220_E	0.774	1.00
88_D	91_L	0.772	1.00
183_A	187_K	0.766	1.00
55_I	83_R	0.762	1.00
184_E	187_K	0.760	1.00
80_L	105_F	0.758	1.00
168_A	172_F	0.757	1.00
87_V	108_R	0.756	1.00
36_G	40_H	0.753	1.00
9_V	65_L	0.748	1.00
173_C	176_P	0.747	1.00
118_L	121_T	0.745	1.00
19_L	110_L	0.739	1.00
69_L	73_A	0.738	1.00
203_V	207_R	0.737	1.00
105_F	110_L	0.735	1.00
17_N	21_S	0.733	1.00
116_N	121_T	0.729	1.00
121_T	125_G	0.727	1.00
116_N	119_S	0.727	1.00
56_N	82_G	0.725	1.00
106_N	109_E	0.721	1.00
172_F	176_P	0.710	1.00
171_H	174_E	0.707	1.00
93_L	113_R	0.707	1.00
36_G	59_G	0.705	1.00
182_R	198_D	0.703	1.00
76_A	124_L	0.698	1.00
213_E	216_P	0.696	1.00
40_H	43_L	0.695	1.00
44_S	68_E	0.695	1.00
138_K	141_G	0.695	1.00
69_L	77_L	0.690	1.00
74_N	124_L	0.690	1.00
215_T	219_P	0.690	1.00
76_A	120_R	0.679	1.00
162_P	211_H	0.678	1.00
18_T	22_I	0.677	1.00
149_R	167_R	0.677	1.00
196_P	201_V	0.675	1.00
78_M	99_D	0.674	1.00
206_R	210_K	0.674	1.00
99_D	116_N	0.671	1.00
8_I	20_K	0.670	1.00
70_R	76_A	0.670	1.00
22_I	111_T	0.670	1.00
43_L	51_V	0.668	1.00
10_E	57_L	0.665	1.00
94_E	112_I	0.661	1.00
8_I	32_E	0.659	1.00
92_G	97_A	0.658	1.00
108_R	112_I	0.658	1.00
36_G	57_L	0.658	1.00
219_P	222_I	0.656	1.00
213_E	220_E	0.656	1.00
187_K	190_T	0.651	1.00
186_L	190_T	0.651	1.00
142_W	154_P	0.650	1.00
63_L	88_D	0.646	1.00
86_E	108_R	0.645	1.00
89_K	106_N	0.644	1.00
52_I	78_M	0.640	1.00
153_G	156_G	0.639	1.00
40_H	72_Q	0.638	1.00
74_N	123_N	0.637	1.00
16_R	20_K	0.636	1.00
209_R	214_S	0.626	1.00
202_D	205_I	0.626	1.00
215_T	220_E	0.625	1.00
70_R	75_V	0.623	1.00
113_R	117_L	0.623	1.00
149_R	166_F	0.623	1.00
105_F	109_E	0.619	1.00
4_P	49_N	0.618	1.00
24_E	30_V	0.617	1.00
115_R	119_S	0.613	1.00
87_V	90_I	0.612	1.00
6_I	50_L	0.609	1.00
76_A	118_L	0.606	1.00
174_E	188_K	0.606	1.00
167_R	171_H	0.604	1.00
197_H	200_T	0.603	1.00
220_E	223_A	0.603	1.00
141_G	154_P	0.601	1.00
112_I	115_R	0.598	1.00
137_Y	141_G	0.597	1.00
23_F	28_Y	0.597	1.00
171_H	176_P	0.596	1.00
196_P	200_T	0.596	1.00
12_E	15_T	0.595	1.00
6_I	23_F	0.593	1.00
54_D	103_K	0.593	1.00
12_E	82_G	0.591	1.00
15_T	18_T	0.589	1.00
66_A	70_R	0.589	1.00
76_A	121_T	0.586	1.00
162_P	165_E	0.577	1.00
81_T	89_K	0.569	1.00
182_R	186_L	0.564	1.00
55_I	92_G	0.562	1.00
53_M	57_L	0.560	1.00
213_E	219_P	0.553	1.00
172_F	205_I	0.549	1.00
22_I	26_E	0.543	1.00
139_F	142_W	0.542	1.00
202_D	206_R	0.538	1.00
43_L	65_L	0.538	1.00
90_I	93_L	0.536	1.00
69_L	75_V	0.533	1.00
219_P	227_G	0.532	1.00
18_T	21_S	0.527	1.00
11_D	81_T	0.526	1.00
137_Y	146_I	0.523	1.00
43_L	72_Q	0.522	1.00
43_L	73_A	0.522	1.00
84_D	104_P	0.522	1.00
137_Y	142_W	0.520	1.00
145_D	150_S	0.520	1.00
38_E	59_G	0.519	1.00
210_K	213_E	0.514	1.00
146_I	174_E	0.511	1.00
164_S	204_T	0.511	1.00
82_G	104_P	0.509	1.00
114_A	118_L	0.509	1.00
120_R	124_L	0.506	1.00
53_M	69_L	0.504	1.00
116_N	120_R	0.504	1.00
11_D	57_L	0.504	1.00
24_E	29_D	0.503	1.00
8_I	16_R	0.502	1.00
9_V	36_G	0.502	1.00
47_D	73_A	0.501	1.00
216_P	220_E	0.500	1.00
139_F	173_C	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2gwrA	1	0.937	100	0.203	Contact Map
4b09A	2	0.8992	100	0.211	Contact Map
1ys7A	2	0.9454	100	0.212	Contact Map
3r0jA	2	0.9286	100	0.218	Contact Map
2oqrA	2	0.9496	100	0.221	Contact Map
4kfcA	2	0.9412	100	0.223	Contact Map
1kgsA	1	0.916	100	0.235	Contact Map
3q9sA	1	0.8824	100	0.254	Contact Map
2hqrA	2	0.916	100	0.267	Contact Map
1p2fA	1	0.9076	100	0.274	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0099 seconds.