DEAD - ECOLI - GREMLIN Contacts

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DEAD - ATP-dependent RNA helicase DeaD

UniProt:	P0A9P6	Sequences: MAEFETTFADLGLKAPILEALNDLGYEKPSPIQAECIPHLLNGRDVLGMAQTGSGKTAAFSLPLLQNLDPELKAPQILVLAPTRELAVQVAEAMTDFSKHMRGVNVVALYGGQRYDVQLRALRQGPQIVVGTPGRLLDHLKRGTLDLSKLSGLVLDEADEMLRMGFIEDVETIMAQIPEGHQTALFSATMPEAIRRITRRFMKEPQEVRIQSSVTTRPDISQSYWTVWGMRKNEALVRFLEAEDFDAAIIFVRTKNATLEVAEALERNGYNSAALNGDMNQALREQTLERLKDGRLDILIATDVAARGLDVERISLVVNYDIPMDSESYVHRIGRTGRAGRAGRALLFVENRERRLLRNIERTMKLTIPEVELPNAELLGKRRLEKFAAKVQQQLESSDLDQYRALLSKIQPTAEGEELDLETLAAALLKMAQGERTLIVPPDAPMRPKREFRDRDDRGPRDRNDRGPRGDREDRPRRERRDVGDMQLYRIEVGRDDGVEVRHIVGAIANEGDISSRYIGNIKLFASHSTIELPKGMPGEVLQHFTRTRILNKPMNMQLLGDAQPHTGGERRGGGRGFGGERREGGRNFSGERREGGRGDGRRFSGERREGRAPRRDDSTGRRRFGGDA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10215
Length:	629 (533)
Sequences:	2665 (2101)
Seq/√Len:	91.0

ECOLI - DEAD RECQ RECG YFJK DBPA RHLE YEJH SRMB RHLB RAPA
BACSU - RECQ CSHA RECG DBPA YPRA CSHB RECS COMFA YFML YWQA
HALSA - HELS Q9HN80 Q9HNB2 RAD25 O52003 Q9HMW5
SULSO - Q981C8 Q97X74 HELS HELX Q97Y93 Q97YC4 Q97WW1 Q97ZF9 Q980C0 Q97WT0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
61_S	94_M	4.917	1.00
65_L	68_L	3.313	1.00
252_V	261_V	2.865	1.00
131_G	136_L	2.862	1.00
94_M	128_I	2.643	1.00
78_L	150_L	2.571	1.00
32_I	48_G	2.554	1.00
503_H	506_G	2.510	1.00
447_R	450_R	2.501	1.00
81_A	90_V	2.471	1.00
23_D	100_H	2.464	1.00
509_A	513_D	2.448	1.00
431_M	438_L	2.420	1.00
250_I	298_I	2.361	1.00
252_V	258_T	2.338	1.00
426_A	433_Q	2.317	1.00
450_R	454_D	2.284	1.00
39_H	208_V	2.248	1.00
497_D	500_E	2.176	1.00
420_D	423_T	2.155	1.00
305_A	309_L	2.145	1.00
519_I	522_I	2.120	1.00
546_T	549_R	2.097	1.00
529_S	534_P	2.093	1.00
558_Q	562_D	2.089	1.00
419_L	430_K	2.074	1.00
232_K	321_D	2.013	1.00
492_E	496_D	2.001	1.00
494_G	497_D	1.990	1.00
490_R	494_G	1.987	1.00
500_E	505_V	1.980	1.00
535_K	538_P	1.967	1.00
425_A	429_L	1.966	1.00
504_I	508_I	1.946	1.00
539_G	542_L	1.941	1.00
563_A	566_H	1.925	1.00
427_A	430_K	1.907	1.00
509_A	512_G	1.906	1.00
424_L	427_A	1.902	1.00
511_E	514_I	1.895	1.00
516_S	519_I	1.893	1.00
236_L	318_V	1.856	1.00
535_K	539_G	1.855	1.00
406_L	409_K	1.853	1.00
558_Q	566_H	1.845	1.00
514_I	517_R	1.841	1.00
444_A	452_F	1.831	1.00
551_L	555_M	1.818	1.00
521_N	525_F	1.813	1.00
558_Q	563_A	1.812	1.00
504_I	507_A	1.803	1.00
543_Q	550_I	1.801	1.00
206_Q	215_T	1.783	1.00
533_L	537_M	1.779	1.00
500_E	504_I	1.777	1.00
510_N	514_I	1.775	1.00
479_E	482_D	1.770	1.00
453_R	456_D	1.755	1.00
158_A	185_L	1.747	1.00
537_M	541_V	1.747	1.00
451_E	454_D	1.741	1.00
433_Q	438_L	1.729	1.00
559_L	563_A	1.729	1.00
543_Q	547_R	1.725	1.00
535_K	544_H	1.714	1.00
558_Q	561_G	1.691	1.00
526_A	531_I	1.682	1.00
544_H	552_N	1.679	1.00
500_E	503_H	1.668	1.00
549_R	554_P	1.666	1.00
408_S	411_Q	1.665	1.00
517_R	520_G	1.665	1.00
548_T	553_K	1.663	1.00
495_R	499_V	1.630	1.00
536_G	539_G	1.628	1.00
534_P	537_M	1.628	1.00
237_V	268_N	1.624	1.00
40_L	184_A	1.620	1.00
442_P	445_P	1.618	1.00
453_R	457_D	1.612	1.00
505_V	508_I	1.609	1.00
549_R	552_N	1.609	1.00
504_I	510_N	1.602	1.00
478_R	481_R	1.601	1.00
539_G	545_F	1.592	1.00
499_V	504_I	1.589	1.00
544_H	548_T	1.589	1.00
445_P	449_K	1.581	1.00
495_R	500_E	1.576	1.00
425_A	430_K	1.575	1.00
499_V	503_H	1.574	1.00
430_K	438_L	1.573	1.00
496_D	499_V	1.571	1.00
497_D	501_V	1.570	1.00
270_Y	298_I	1.569	1.00
511_E	519_I	1.565	1.00
530_T	534_P	1.565	1.00
452_F	455_R	1.561	1.00
430_K	434_G	1.555	1.00
455_R	458_R	1.554	1.00
529_S	533_L	1.553	1.00
64_L	68_L	1.548	1.00
541_V	545_F	1.542	1.00
430_K	436_R	1.538	1.00
454_D	458_R	1.537	1.00
481_R	485_D	1.527	1.00
427_A	431_M	1.517	1.00
405_A	411_Q	1.515	1.00
550_I	553_K	1.507	1.00
496_D	501_V	1.507	1.00
560_L	564_Q	1.505	1.00
431_M	434_G	1.503	1.00
526_A	530_T	1.498	1.00
444_A	447_R	1.495	1.00
403_Y	409_K	1.492	1.00
262_A	272_S	1.492	1.00
428_L	433_Q	1.478	1.00
555_M	559_L	1.475	1.00
554_P	559_L	1.471	1.00
477_R	480_R	1.460	1.00
120_R	123_R	1.459	1.00
431_M	436_R	1.455	0.99
429_L	439_I	1.447	0.99
552_N	558_Q	1.446	0.99
513_D	517_R	1.445	0.99
533_L	538_P	1.440	0.99
217_R	222_Q	1.429	0.99
405_A	408_S	1.420	0.99
533_L	543_Q	1.418	0.99
541_V	548_T	1.418	0.99
404_R	408_S	1.413	0.99
563_A	567_T	1.410	0.99
64_L	67_N	1.409	0.99
496_D	504_I	1.407	0.99
429_L	434_G	1.406	0.99
518_Y	522_I	1.402	0.99
532_E	535_K	1.402	0.99
444_A	448_P	1.389	0.99
502_R	506_G	1.389	0.99
430_K	433_Q	1.388	0.99
502_R	505_V	1.388	0.99
550_I	554_P	1.379	0.99
392_Q	395_L	1.377	0.99
451_E	455_R	1.369	0.99
446_M	449_K	1.368	0.99
484_G	487_Q	1.367	0.99
368_I	373_L	1.366	0.99
544_H	550_I	1.360	0.99
532_E	536_G	1.356	0.99
454_D	457_D	1.355	0.99
503_H	509_A	1.348	0.99
252_V	300_I	1.344	0.99
511_E	515_S	1.333	0.99
507_A	512_G	1.328	0.99
427_A	433_Q	1.324	0.99
446_M	450_R	1.324	0.99
537_M	547_R	1.323	0.99
450_R	455_R	1.321	0.99
343_G	347_L	1.313	0.99
450_R	453_R	1.312	0.99
515_S	519_I	1.310	0.99
322_I	347_L	1.309	0.99
533_L	539_G	1.308	0.99
479_E	483_V	1.306	0.99
557_M	560_L	1.305	0.99
417_E	421_L	1.302	0.99
429_L	437_T	1.300	0.99
442_P	446_M	1.299	0.99
502_R	510_N	1.293	0.99
518_Y	521_N	1.292	0.99
494_G	504_I	1.281	0.99
545_F	549_R	1.279	0.99
511_E	517_R	1.274	0.99
559_L	566_H	1.268	0.99
94_M	130_V	1.266	0.99
559_L	565_P	1.264	0.99
564_Q	567_T	1.261	0.99
289_E	293_D	1.261	0.99
501_V	505_V	1.254	0.98
556_N	559_L	1.253	0.98
456_D	461_R	1.253	0.98
545_F	548_T	1.245	0.98
23_D	99_K	1.243	0.98
399_D	403_Y	1.238	0.98
477_R	482_D	1.238	0.98
421_L	425_A	1.237	0.98
544_H	547_R	1.228	0.98
449_K	452_F	1.228	0.98
534_P	544_H	1.228	0.98
550_I	557_M	1.226	0.98
371_V	374_P	1.224	0.98
558_Q	567_T	1.220	0.98
436_R	439_I	1.219	0.98
527_S	530_T	1.216	0.98
417_E	432_A	1.213	0.98
543_Q	552_N	1.209	0.98
552_N	564_Q	1.209	0.98
445_P	451_E	1.207	0.98
433_Q	437_T	1.205	0.98
557_M	565_P	1.202	0.98
504_I	511_E	1.199	0.98
532_E	539_G	1.195	0.98
557_M	566_H	1.193	0.98
419_L	423_T	1.191	0.98
535_K	541_V	1.190	0.98
480_R	484_G	1.190	0.98
552_N	566_H	1.187	0.98
558_Q	565_P	1.185	0.98
44_R	206_Q	1.183	0.98
526_A	529_S	1.179	0.98
431_M	435_E	1.179	0.98
159_D	307_R	1.177	0.98
417_E	423_T	1.176	0.98
503_H	508_I	1.174	0.98
512_G	515_S	1.171	0.98
506_G	510_N	1.171	0.98
483_V	487_Q	1.169	0.98
255_K	278_D	1.167	0.98
515_S	518_Y	1.167	0.98
547_R	557_M	1.163	0.98
560_L	565_P	1.158	0.97
534_P	538_P	1.157	0.97
513_D	519_I	1.154	0.97
535_K	549_R	1.152	0.97
418_E	421_L	1.151	0.97
507_A	511_E	1.150	0.97
547_R	551_L	1.148	0.97
425_A	428_L	1.144	0.97
514_I	518_Y	1.142	0.97
433_Q	436_R	1.141	0.97
482_D	486_M	1.140	0.97
432_A	436_R	1.140	0.97
539_G	543_Q	1.137	0.97
451_E	461_R	1.134	0.97
428_L	437_T	1.133	0.97
435_E	439_I	1.133	0.97
538_P	541_V	1.130	0.97
505_V	509_A	1.129	0.97
63_P	68_L	1.127	0.97
507_A	510_N	1.126	0.97
432_A	435_E	1.122	0.97
423_T	426_A	1.122	0.97
557_M	562_D	1.121	0.97
499_V	505_V	1.120	0.97
420_D	424_L	1.114	0.97
406_L	411_Q	1.113	0.97
548_T	551_L	1.112	0.97
202_M	205_P	1.111	0.97
533_L	536_G	1.109	0.97
506_G	509_A	1.107	0.97
405_A	409_K	1.106	0.97
425_A	432_A	1.104	0.97
536_G	540_E	1.095	0.96
499_V	510_N	1.092	0.96
549_R	557_M	1.091	0.96
526_A	548_T	1.091	0.96
496_D	500_E	1.090	0.96
510_N	513_D	1.088	0.96
560_L	563_A	1.084	0.96
407_L	410_I	1.084	0.96
560_L	566_H	1.083	0.96
424_L	428_L	1.080	0.96
477_R	481_R	1.078	0.96
546_T	553_K	1.073	0.96
499_V	502_R	1.069	0.96
265_L	300_I	1.064	0.96
424_L	434_G	1.061	0.96
436_R	440_V	1.060	0.96
513_D	516_S	1.057	0.96
401_D	405_A	1.056	0.96
559_L	562_D	1.056	0.96
510_N	516_S	1.051	0.95
557_M	564_Q	1.050	0.95
542_L	546_T	1.050	0.95
564_Q	568_G	1.048	0.95
428_L	438_L	1.045	0.95
434_G	437_T	1.044	0.95
535_K	546_T	1.044	0.95
417_E	428_L	1.043	0.95
381_K	386_K	1.040	0.95
423_T	432_A	1.038	0.95
427_A	434_G	1.038	0.95
482_D	487_Q	1.037	0.95
413_T	424_L	1.037	0.95
167_I	171_E	1.037	0.95
554_P	558_Q	1.036	0.95
403_Y	410_I	1.035	0.95
444_A	450_R	1.031	0.95
553_K	558_Q	1.029	0.95
426_A	431_M	1.028	0.95
442_P	448_P	1.026	0.95
388_A	395_L	1.026	0.95
541_V	553_K	1.025	0.95
532_E	543_Q	1.025	0.95
368_I	371_V	1.025	0.95
496_D	503_H	1.022	0.95
512_G	517_R	1.020	0.95
545_F	555_M	1.020	0.95
529_S	536_G	1.018	0.95
495_R	503_H	1.018	0.95
491_I	507_A	1.016	0.95
540_E	552_N	1.015	0.95
15_A	19_E	1.012	0.94
546_T	550_I	1.009	0.94
534_P	540_E	1.008	0.94
402_Q	405_A	1.006	0.94
562_D	567_T	1.003	0.94
533_L	540_E	1.003	0.94
19_E	100_H	1.002	0.94
562_D	565_P	1.002	0.94
555_M	558_Q	1.002	0.94
491_I	494_G	1.001	0.94
384_L	387_F	0.993	0.94
534_P	556_N	0.992	0.94
555_M	567_T	0.992	0.94
539_G	544_H	0.987	0.94
381_K	390_K	0.987	0.94
17_I	66_Q	0.986	0.94
239_F	346_L	0.986	0.94
417_E	420_D	0.985	0.94
548_T	557_M	0.983	0.94
503_H	507_A	0.982	0.94
430_K	439_I	0.981	0.93
355_R	360_I	0.980	0.93
413_T	429_L	0.979	0.93
430_K	437_T	0.977	0.93
413_T	438_L	0.977	0.93
550_I	559_L	0.976	0.93
427_A	436_R	0.971	0.93
425_A	433_Q	0.970	0.93
360_I	367_T	0.969	0.93
544_H	558_Q	0.969	0.93
421_L	433_Q	0.967	0.93
432_A	441_P	0.967	0.93
419_L	432_A	0.965	0.93
519_I	523_K	0.965	0.93
422_E	426_A	0.965	0.93
481_R	484_G	0.963	0.93
498_G	513_D	0.963	0.93
421_L	424_L	0.961	0.93
537_M	540_E	0.959	0.93
544_H	551_L	0.957	0.93
529_S	552_N	0.952	0.92
448_P	451_E	0.952	0.92
555_M	560_L	0.951	0.92
425_A	434_G	0.947	0.92
548_T	555_M	0.947	0.92
382_R	386_K	0.946	0.92
429_L	436_R	0.943	0.92
498_G	502_R	0.942	0.92
501_V	506_G	0.942	0.92
63_P	67_N	0.939	0.92
553_K	556_N	0.937	0.92
517_R	522_I	0.935	0.92
159_D	331_H	0.934	0.92
343_G	349_V	0.934	0.92
508_I	512_G	0.933	0.92
261_V	300_I	0.932	0.92
535_K	554_P	0.932	0.92
531_I	550_I	0.930	0.92
446_M	451_E	0.924	0.91
543_Q	553_K	0.922	0.91
452_F	456_D	0.922	0.91
506_G	511_E	0.920	0.91
519_I	525_F	0.919	0.91
494_G	501_V	0.918	0.91
501_V	507_A	0.916	0.91
401_D	404_R	0.913	0.91
555_M	565_P	0.911	0.91
538_P	551_L	0.911	0.91
492_E	497_D	0.909	0.91
444_A	449_K	0.908	0.91
449_K	457_D	0.906	0.90
542_L	559_L	0.906	0.90
449_K	455_R	0.905	0.90
119_L	123_R	0.904	0.90
426_A	432_A	0.902	0.90
508_I	514_I	0.900	0.90
534_P	568_G	0.900	0.90
428_L	431_M	0.900	0.90
563_A	568_G	0.896	0.90
326_S	363_T	0.890	0.90
536_G	545_F	0.889	0.90
482_D	485_D	0.887	0.89
420_D	430_K	0.887	0.89
532_E	541_V	0.886	0.89
76_Q	127_Q	0.886	0.89
529_S	537_M	0.886	0.89
540_E	544_H	0.878	0.89
527_S	533_L	0.877	0.89
557_M	563_A	0.877	0.89
552_N	555_M	0.876	0.89
498_G	501_V	0.875	0.89
561_G	565_P	0.875	0.89
539_G	547_R	0.873	0.89
510_N	515_S	0.867	0.88
562_D	566_H	0.866	0.88
217_R	220_I	0.866	0.88
542_L	554_P	0.861	0.88
490_R	500_E	0.861	0.88
358_R	361_E	0.860	0.88
532_E	565_P	0.859	0.88
544_H	553_K	0.859	0.88
447_R	451_E	0.856	0.88
478_R	482_D	0.854	0.88
538_P	544_H	0.854	0.88
424_L	432_A	0.853	0.88
548_T	566_H	0.852	0.88
356_L	361_E	0.850	0.87
521_N	524_L	0.849	0.87
222_Q	329_Y	0.848	0.87
552_N	556_N	0.846	0.87
544_H	549_R	0.846	0.87
498_G	510_N	0.844	0.87
512_G	516_S	0.842	0.87
540_E	543_Q	0.842	0.87
387_F	391_V	0.841	0.87
447_R	455_R	0.839	0.87
550_I	555_M	0.839	0.87
545_F	565_P	0.839	0.87
479_E	485_D	0.837	0.87
510_N	518_Y	0.837	0.87
516_S	524_L	0.837	0.87
424_L	431_M	0.836	0.87
499_V	506_G	0.836	0.87
491_I	501_V	0.836	0.87
532_E	540_E	0.835	0.86
558_Q	568_G	0.833	0.86
534_P	543_Q	0.832	0.86
476_P	480_R	0.832	0.86
530_T	550_I	0.830	0.86
421_L	430_K	0.829	0.86
422_E	437_T	0.828	0.86
535_K	543_Q	0.828	0.86
495_R	504_I	0.828	0.86
419_L	429_L	0.828	0.86
500_E	512_G	0.826	0.86
423_T	439_I	0.824	0.86
402_Q	409_K	0.823	0.86
542_L	558_Q	0.823	0.86
418_E	423_T	0.821	0.86
259_L	274_A	0.819	0.85
555_M	561_G	0.816	0.85
431_M	437_T	0.815	0.85
535_K	545_F	0.814	0.85
445_P	454_D	0.811	0.85
541_V	544_H	0.811	0.85
539_G	563_A	0.810	0.85
552_N	568_G	0.810	0.85
544_H	556_N	0.809	0.85
516_S	522_I	0.809	0.85
449_K	453_R	0.808	0.85
319_N	333_I	0.808	0.85
518_Y	523_K	0.805	0.84
547_R	567_T	0.804	0.84
546_T	554_P	0.803	0.84
424_L	438_L	0.801	0.84
408_S	412_P	0.801	0.84
529_S	542_L	0.800	0.84
98_S	104_V	0.799	0.84
541_V	557_M	0.796	0.84
352_R	355_R	0.796	0.84
529_S	543_Q	0.795	0.84
537_M	553_K	0.794	0.84
486_M	490_R	0.794	0.84
539_G	549_R	0.794	0.84
430_K	435_E	0.793	0.83
404_R	409_K	0.793	0.83
541_V	549_R	0.792	0.83
512_G	536_G	0.792	0.83
450_R	456_D	0.790	0.83
432_A	437_T	0.790	0.83
481_R	486_M	0.789	0.83
552_N	557_M	0.786	0.83
449_K	454_D	0.786	0.83
495_R	515_S	0.785	0.83
542_L	548_T	0.781	0.83
406_L	410_I	0.781	0.83
497_D	504_I	0.780	0.82
478_R	484_G	0.776	0.82
452_F	457_D	0.775	0.82
530_T	535_K	0.775	0.82
273_A	290_R	0.772	0.82
494_G	499_V	0.770	0.82
416_G	428_L	0.769	0.82
536_G	552_N	0.768	0.82
556_N	566_H	0.765	0.81
547_R	550_I	0.763	0.81
493_V	500_E	0.762	0.81
549_R	553_K	0.762	0.81
544_H	557_M	0.761	0.81
504_I	516_S	0.760	0.81
551_L	558_Q	0.760	0.81
507_A	516_S	0.760	0.81
528_H	531_I	0.759	0.81
427_A	438_L	0.759	0.81
425_A	435_E	0.758	0.81
429_L	435_E	0.756	0.80
555_M	562_D	0.756	0.80
536_G	558_Q	0.755	0.80
423_T	430_K	0.754	0.80
445_P	453_R	0.754	0.80
525_F	534_P	0.753	0.80
38_P	309_L	0.752	0.80
525_F	528_H	0.751	0.80
546_T	557_M	0.750	0.80
236_L	250_I	0.749	0.80
556_N	560_L	0.749	0.80
538_P	546_T	0.747	0.80
384_L	388_A	0.743	0.79
534_P	548_T	0.736	0.79
424_L	429_L	0.734	0.78
492_E	499_V	0.733	0.78
546_T	562_D	0.732	0.78
559_L	564_Q	0.732	0.78
548_T	559_L	0.732	0.78
395_L	403_Y	0.731	0.78
428_L	432_A	0.729	0.78
549_R	555_M	0.729	0.78
80_L	131_G	0.729	0.78
387_F	390_K	0.727	0.78
421_L	426_A	0.726	0.78
385_E	390_K	0.725	0.78
506_G	516_S	0.725	0.78
448_P	458_R	0.725	0.78
538_P	562_D	0.723	0.77
316_L	346_L	0.722	0.77
434_G	438_L	0.721	0.77
379_L	386_K	0.721	0.77
533_L	541_V	0.721	0.77
498_G	507_A	0.720	0.77
307_R	331_H	0.720	0.77
381_K	385_E	0.719	0.77
553_K	564_Q	0.719	0.77
545_F	557_M	0.718	0.77
552_N	563_A	0.717	0.77
403_Y	411_Q	0.717	0.77
507_A	513_D	0.717	0.77
61_S	93_A	0.712	0.76
514_I	522_I	0.712	0.76
432_A	438_L	0.711	0.76
552_N	567_T	0.711	0.76
499_V	511_E	0.711	0.76
530_T	541_V	0.710	0.76
492_E	495_R	0.709	0.76
496_D	514_I	0.708	0.76
333_I	345_A	0.708	0.76
561_G	568_G	0.706	0.76
494_G	502_R	0.705	0.76
118_Q	121_A	0.705	0.76
420_D	432_A	0.704	0.76
500_E	510_N	0.703	0.75
403_Y	408_S	0.702	0.75
43_G	182_Q	0.700	0.75
357_L	361_E	0.700	0.75
93_A	97_F	0.699	0.75
547_R	561_G	0.699	0.75
420_D	436_R	0.698	0.75
529_S	535_K	0.694	0.75
525_F	529_S	0.694	0.75
553_K	557_M	0.692	0.74
286_Q	290_R	0.692	0.74
428_L	434_G	0.689	0.74
504_I	512_G	0.685	0.74
492_E	506_G	0.684	0.73
504_I	509_A	0.683	0.73
554_P	563_A	0.683	0.73
445_P	450_R	0.682	0.73
520_G	523_K	0.680	0.73
403_Y	406_L	0.680	0.73
522_I	525_F	0.679	0.73
418_E	427_A	0.678	0.73
543_Q	560_L	0.677	0.73
36_C	46_V	0.677	0.73
424_L	435_E	0.677	0.73
527_S	539_G	0.676	0.73
530_T	537_M	0.676	0.73
419_L	435_E	0.675	0.72
499_V	508_I	0.674	0.72
20_A	100_H	0.673	0.72
514_I	519_I	0.672	0.72
561_G	564_Q	0.671	0.72
432_A	439_I	0.670	0.72
529_S	539_G	0.668	0.72
369_P	372_E	0.667	0.72
522_I	528_H	0.667	0.72
537_M	542_L	0.667	0.72
558_Q	564_Q	0.666	0.71
425_A	431_M	0.666	0.71
536_G	546_T	0.665	0.71
476_P	479_E	0.664	0.71
208_V	214_V	0.664	0.71
547_R	554_P	0.663	0.71
547_R	568_G	0.661	0.71
545_F	563_A	0.661	0.71
85_E	89_Q	0.659	0.71
216_T	222_Q	0.658	0.71
495_R	506_G	0.657	0.70
523_K	527_S	0.657	0.70
536_G	544_H	0.655	0.70
421_L	431_M	0.655	0.70
210_I	214_V	0.654	0.70
496_D	510_N	0.654	0.70
391_V	396_E	0.653	0.70
553_K	567_T	0.653	0.70
514_I	521_N	0.652	0.70
424_L	433_Q	0.652	0.70
399_D	411_Q	0.652	0.70
422_E	438_L	0.652	0.70
419_L	422_E	0.650	0.70
500_E	508_I	0.649	0.70
424_L	430_K	0.649	0.70
552_N	559_L	0.648	0.69
394_Q	398_S	0.648	0.69
547_R	552_N	0.647	0.69
557_M	561_G	0.645	0.69
499_V	507_A	0.644	0.69
500_E	507_A	0.644	0.69
444_A	454_D	0.642	0.69
361_E	364_M	0.640	0.68
503_H	516_S	0.640	0.68
556_N	562_D	0.640	0.68
493_V	496_D	0.639	0.68
447_R	452_F	0.638	0.68
527_S	537_M	0.638	0.68
545_F	554_P	0.635	0.68
529_S	550_I	0.635	0.68
547_R	559_L	0.634	0.68
536_G	547_R	0.633	0.68
532_E	538_P	0.632	0.67
429_L	432_A	0.630	0.67
222_Q	333_I	0.628	0.67
404_R	410_I	0.628	0.67
479_E	484_G	0.627	0.67
555_M	563_A	0.626	0.67
495_R	507_A	0.625	0.67
483_V	486_M	0.624	0.67
207_E	210_I	0.621	0.66
417_E	444_A	0.620	0.66
94_M	106_V	0.618	0.66
540_E	545_F	0.618	0.66
419_L	438_L	0.617	0.66
385_E	389_A	0.617	0.66
178_P	181_H	0.616	0.66
494_G	500_E	0.616	0.66
552_N	565_P	0.615	0.65
544_H	554_P	0.615	0.65
134_G	160_E	0.613	0.65
497_D	502_R	0.612	0.65
532_E	537_M	0.611	0.65
381_K	384_L	0.610	0.65
543_Q	549_R	0.610	0.65
413_T	433_Q	0.609	0.65
126_P	129_V	0.609	0.65
429_L	438_L	0.609	0.65
421_L	427_A	0.607	0.64
381_K	398_S	0.607	0.64
539_G	561_G	0.605	0.64
480_R	483_V	0.605	0.64
505_V	510_N	0.605	0.64
190_M	337_G	0.604	0.64
387_F	395_L	0.604	0.64
543_Q	565_P	0.604	0.64
541_V	550_I	0.604	0.64
538_P	558_Q	0.604	0.64
21_L	58_A	0.603	0.64
209_R	212_S	0.602	0.64
554_P	557_M	0.602	0.64
537_M	545_F	0.602	0.64
83_T	307_R	0.602	0.64
536_G	551_L	0.601	0.64
413_T	430_K	0.600	0.63
233_N	261_V	0.600	0.63
356_L	360_I	0.600	0.63
536_G	542_L	0.599	0.63
449_K	456_D	0.599	0.63
381_K	389_A	0.599	0.63
540_E	557_M	0.596	0.63
553_K	560_L	0.596	0.63
83_T	134_G	0.595	0.63
540_E	546_T	0.594	0.63
84_R	134_G	0.593	0.63
507_A	515_S	0.592	0.62
562_D	568_G	0.592	0.62
505_V	511_E	0.591	0.62
247_A	315_S	0.590	0.62
451_E	458_R	0.589	0.62
85_E	331_H	0.588	0.62
491_I	504_I	0.588	0.62
505_V	515_S	0.586	0.62
552_N	561_G	0.586	0.62
394_Q	397_S	0.585	0.62
551_L	562_D	0.585	0.62
407_L	412_P	0.583	0.61
445_P	448_P	0.583	0.61
531_I	534_P	0.583	0.61
448_P	452_F	0.583	0.61
477_R	483_V	0.583	0.61
423_T	428_L	0.582	0.61
369_P	374_P	0.580	0.61
560_L	568_G	0.579	0.61
556_N	564_Q	0.579	0.61
554_P	565_P	0.578	0.61
416_G	437_T	0.578	0.61
413_T	416_G	0.577	0.61
548_T	554_P	0.576	0.60
535_K	548_T	0.575	0.60
335_R	338_R	0.575	0.60
538_P	556_N	0.574	0.60
413_T	439_I	0.574	0.60
458_R	461_R	0.573	0.60
484_G	497_D	0.573	0.60
493_V	502_R	0.572	0.60
402_Q	408_S	0.572	0.60
435_E	441_P	0.571	0.60
524_L	528_H	0.569	0.59
537_M	544_H	0.568	0.59
543_Q	558_Q	0.568	0.59
420_D	433_Q	0.567	0.59
509_A	518_Y	0.565	0.59
551_L	567_T	0.565	0.59
534_P	541_V	0.564	0.59
420_D	439_I	0.562	0.59
220_I	337_G	0.560	0.58
533_L	544_H	0.560	0.58
425_A	439_I	0.559	0.58
137_L	256_N	0.558	0.58
520_G	527_S	0.557	0.58
536_G	548_T	0.556	0.58
529_S	549_R	0.555	0.58
457_D	461_R	0.552	0.57
551_L	554_P	0.552	0.57
503_H	510_N	0.552	0.57
540_E	551_L	0.551	0.57
517_R	526_A	0.549	0.57
513_D	520_G	0.549	0.57
442_P	447_R	0.548	0.57
499_V	516_S	0.547	0.56
446_M	454_D	0.546	0.56
528_H	548_T	0.546	0.56
534_P	542_L	0.546	0.56
543_Q	546_T	0.546	0.56
493_V	499_V	0.545	0.56
417_E	436_R	0.544	0.56
511_E	528_H	0.544	0.56
526_A	533_L	0.543	0.56
519_I	529_S	0.543	0.56
448_P	455_R	0.543	0.56
503_H	512_G	0.542	0.56
396_E	400_L	0.541	0.56
415_E	422_E	0.541	0.56
434_G	439_I	0.539	0.55
450_R	478_R	0.538	0.55
395_L	398_S	0.538	0.55
549_R	558_Q	0.537	0.55
542_L	557_M	0.535	0.55
518_Y	528_H	0.535	0.55
395_L	409_K	0.535	0.55
506_G	515_S	0.535	0.55
520_G	524_L	0.535	0.55
413_T	418_E	0.534	0.55
398_S	401_D	0.534	0.55
420_D	426_A	0.533	0.55
19_E	23_D	0.532	0.54
88_V	285_E	0.530	0.54
405_A	410_I	0.529	0.54
45_D	205_P	0.529	0.54
526_A	541_V	0.529	0.54
134_G	307_R	0.525	0.53
541_V	551_L	0.523	0.53
428_L	439_I	0.522	0.53
541_V	556_N	0.522	0.53
534_P	545_F	0.522	0.53
545_F	551_L	0.521	0.53
539_G	562_D	0.520	0.53
422_E	427_A	0.519	0.53
382_R	390_K	0.519	0.53
553_K	565_P	0.518	0.52
533_L	552_N	0.517	0.52
343_G	350_E	0.514	0.52
421_L	439_I	0.513	0.52
391_V	398_S	0.513	0.52
84_R	87_A	0.512	0.52
415_E	419_L	0.512	0.52
498_G	504_I	0.511	0.52
491_I	497_D	0.511	0.52
554_P	568_G	0.510	0.51
535_K	540_E	0.510	0.51
89_Q	334_G	0.509	0.51
531_I	542_L	0.509	0.51
554_P	564_Q	0.509	0.51
517_R	521_N	0.507	0.51
548_T	565_P	0.504	0.51
419_L	425_A	0.504	0.51
419_L	427_A	0.503	0.50
535_K	565_P	0.503	0.50
456_D	462_D	0.503	0.50
137_L	141_K	0.502	0.50
534_P	539_G	0.502	0.50
557_M	567_T	0.500	0.50

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4pxaA	1	0.6025	100	0.361	Contact Map
4nhoA	1	0.593	100	0.374	Contact Map
2db3A	1	0.5946	100	0.375	Contact Map
4ljyA	1	0.6232	100	0.378	Contact Map
4d25A	1	0.5962	100	0.387	Contact Map
3fmpB	1	0.3307	100	0.39	Contact Map
4c9bA	1	0.5978	100	0.394	Contact Map
3sqwA	1	0.7329	100	0.396	Contact Map
3i5xA	1	0.7345	100	0.402	Contact Map
3eiqA	1	0.5676	100	0.402	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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