DLDH - ECOLI - GREMLIN Contacts

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DLDH - Dihydrolipoyl dehydrogenase

UniProt:	P0A9P0	Sequences: MSTEIKTQVVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGGVCLNVGCIPSKALLHVAKVIEEAKALAEHGIVFGEPKTDIDKIRTWKEKVINQLTGGLAGMAKGRKVKVVNGLGKFTGANTLEVEGENGKTVINFDNAIIAAGSRPIQLPFIPHEDPRIWDSTDALELKEVPERLLVMGGGIIGLEMGTVYHALGSQIDVVEMFDQVIPAADKDIVKVFTKRISKKFNLMLETKVTAVEAKEDGIYVTMEGKKAPAEPQRYDAVLVAIGRVPNGKNLDAGKAGVEVDDRGFIRVDKQLRTNVPHIFAIGDIVGQPMLAHKGVHEGHVAAEVIAGKKHYFDPKVIPSIAYTEPEVAWVGLTEKEAKEKGISYETATFPWAASGRAIASDCADGMTKLIFDKESHRVIGGAIVGTNGGELLGEIGLAIEMGCDAEDIALTIHAHPTLHESVGLAAEVFEGSITDLPNPKAKKK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10543
Length:	474 (447)
Sequences:	14371 (9611)
Seq/√Len:	454.6

ECOLI - DLDH STHA GSHR RCLA HCAD NORW
BACSU - DLDH1 DLDH3 DLDH2
HALSA - DLDH Q9HSN0 Q9HP48 Q9HR27
SULSO - Q97VD9 Q97XZ3 Q97Z19 Q97WE3 Q97VQ4 Q97Y24 Q97YT2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
37_R	116_L	4.411	1.00
179_L	264_Y	4.132	1.00
298_D	302_R	3.867	1.00
177_R	200_Q	3.055	1.00
288_E	296_R	2.914	1.00
411_G	425_I	2.885	1.00
121_G	124_T	2.864	1.00
200_Q	231_N	2.694	1.00
202_D	233_M	2.623	1.00
373_S	404_E	2.566	1.00
7_T	111_K	2.541	1.00
6_K	139_D	2.505	1.00
281_D	284_K	2.483	1.00
148_R	278_K	2.472	1.00
7_T	33_V	2.447	1.00
373_S	403_K	2.445	1.00
249_Y	261_P	2.428	1.00
223_T	227_S	2.421	1.00
240_A	251_T	2.408	1.00
402_D	405_S	2.385	1.00
6_K	137_N	2.369	1.00
242_E	251_T	2.317	1.00
424_E	443_H	2.315	1.00
21_A	142_I	2.298	1.00
174_V	199_S	2.286	1.00
150_I	274_V	2.273	1.00
299_K	341_Y	2.257	1.00
148_R	276_N	2.244	1.00
216_K	365_K	2.229	1.00
375_E	403_K	2.225	1.00
138_F	141_A	2.204	1.00
33_V	113_V	2.191	1.00
126_E	135_V	2.188	1.00
177_R	265_D	2.175	1.00
124_T	135_V	2.118	1.00
290_D	294_F	2.113	1.00
406_H	436_E	2.112	1.00
10_V	136_I	2.093	1.00
362_L	370_K	2.088	1.00
254_G	260_E	2.068	1.00
233_M	260_E	2.063	1.00
179_L	204_V	2.057	1.00
407_R	432_G	2.050	1.00
9_V	25_C	2.040	1.00
237_K	253_E	2.028	1.00
362_L	367_A	2.027	1.00
155_I	240_A	2.020	1.00
331_A	335_I	1.997	1.00
239_T	253_E	1.996	1.00
249_Y	263_R	1.966	1.00
17_A	311_I	1.951	1.00
242_E	249_Y	1.946	1.00
179_L	250_V	1.933	1.00
208_D	235_E	1.925	1.00
428_A	433_C	1.908	1.00
188_L	203_V	1.906	1.00
120_T	126_E	1.888	1.00
413_I	418_G	1.874	1.00
10_V	35_V	1.855	1.00
118_K	126_E	1.829	1.00
140_N	307_H	1.820	1.00
148_R	274_V	1.814	1.00
364_E	368_K	1.797	1.00
75_V	82_D	1.778	1.00
164_D	167_D	1.771	1.00
120_T	135_V	1.757	1.00
10_V	125_L	1.755	1.00
8_Q	31_E	1.754	1.00
374_Y	400_I	1.742	1.00
195_H	200_Q	1.736	1.00
75_V	80_K	1.701	1.00
35_V	136_I	1.695	1.00
244_K	249_Y	1.688	1.00
251_T	261_P	1.669	1.00
365_K	369_E	1.668	1.00
10_V	138_F	1.645	1.00
119_F	141_A	1.639	1.00
236_T	254_G	1.631	1.00
302_R	306_P	1.625	1.00
178_L	194_Y	1.584	1.00
143_I	314_I	1.584	1.00
206_M	237_K	1.584	1.00
399_L	411_G	1.583	1.00
178_L	199_S	1.573	1.00
8_Q	139_D	1.566	1.00
12_L	117_G	1.565	1.00
142_I	335_I	1.564	1.00
82_D	85_K	1.558	1.00
209_Q	219_V	1.541	1.00
364_E	398_K	1.530	1.00
356_E	419_G	1.529	1.00
188_L	353_T	1.528	1.00
367_A	374_Y	1.521	1.00
10_V	33_V	1.514	1.00
124_T	137_N	1.507	1.00
9_V	30_L	1.501	1.00
113_V	136_I	1.499	1.00
309_F	334_V	1.497	1.00
163_W	266_A	1.495	1.00
196_A	229_K	1.473	1.00
217_D	378_T	1.456	1.00
125_L	129_G	1.451	1.00
202_D	231_N	1.445	1.00
102_A	114_N	1.442	1.00
434_D	437_D	1.435	1.00
372_I	409_I	1.433	1.00
239_T	251_T	1.427	1.00
162_I	241_V	1.418	1.00
85_K	88_T	1.417	1.00
252_M	262_Q	1.414	1.00
145_A	314_I	1.413	1.00
221_V	414_V	1.393	1.00
176_E	200_Q	1.383	1.00
140_N	335_I	1.382	1.00
233_M	236_T	1.380	1.00
366_E	369_E	1.372	1.00
122_A	305_V	1.372	1.00
195_H	230_F	1.371	1.00
176_E	265_D	1.354	1.00
367_A	400_I	1.351	1.00
301_L	315_V	1.342	1.00
126_E	133_K	1.341	1.00
31_E	111_K	1.337	1.00
163_W	171_L	1.336	1.00
91_E	95_N	1.332	1.00
24_R	333_E	1.318	1.00
300_Q	334_V	1.317	1.00
247_G	263_R	1.317	1.00
288_E	304_N	1.312	1.00
68_A	71_E	1.307	1.00
35_V	117_G	1.302	1.00
62_V	65_E	1.297	1.00
399_L	456_A	1.295	1.00
290_D	296_R	1.273	1.00
9_V	142_I	1.271	1.00
33_V	136_I	1.267	1.00
376_T	400_I	1.263	1.00
142_I	311_I	1.262	1.00
161_R	243_A	1.260	1.00
115_G	127_V	1.250	1.00
333_E	340_H	1.248	1.00
215_D	398_K	1.245	1.00
75_V	85_K	1.243	1.00
302_R	307_H	1.241	1.00
41_L	112_V	1.235	1.00
7_T	113_V	1.214	1.00
168_A	194_Y	1.210	1.00
217_D	398_K	1.204	1.00
373_S	402_D	1.202	1.00
218_I	414_V	1.196	1.00
252_M	260_E	1.192	1.00
225_R	228_K	1.190	1.00
285_A	305_V	1.184	1.00
305_V	308_I	1.181	1.00
236_T	252_M	1.181	1.00
183_G	210_V	1.175	1.00
119_F	125_L	1.175	1.00
224_K	227_S	1.169	1.00
244_K	247_G	1.168	1.00
204_V	252_M	1.165	1.00
125_L	307_H	1.158	1.00
381_W	415_G	1.155	1.00
119_F	284_K	1.154	1.00
48_V	166_T	1.152	1.00
216_K	220_K	1.149	1.00
402_D	407_R	1.149	1.00
223_T	232_L	1.141	1.00
118_K	281_D	1.141	1.00
431_M	437_D	1.141	1.00
241_V	267_V	1.139	1.00
252_M	255_K	1.139	1.00
209_Q	216_K	1.134	1.00
218_I	396_M	1.134	1.00
159_D	243_A	1.132	1.00
87_R	91_E	1.132	1.00
349_S	359_W	1.126	1.00
214_A	359_W	1.126	1.00
243_A	247_G	1.120	1.00
92_K	96_Q	1.116	1.00
118_K	128_E	1.113	1.00
119_F	143_I	1.112	1.00
222_F	414_V	1.106	1.00
364_E	376_T	1.106	1.00
181_M	267_V	1.105	1.00
328_G	332_A	1.104	1.00
311_I	331_A	1.099	1.00
399_L	425_I	1.098	1.00
123_N	307_H	1.095	1.00
214_A	349_S	1.094	1.00
350_I	444_A	1.094	1.00
350_I	419_G	1.092	1.00
204_V	262_Q	1.090	1.00
300_Q	341_Y	1.090	1.00
287_V	295_I	1.088	1.00
12_L	143_I	1.085	1.00
295_I	314_I	1.083	1.00
425_I	452_V	1.080	1.00
244_K	263_R	1.080	1.00
397_T	451_S	1.072	1.00
203_V	232_L	1.071	1.00
223_T	234_L	1.068	1.00
161_R	248_I	1.067	1.00
242_E	261_P	1.066	1.00
17_A	324_G	1.064	1.00
102_A	106_K	1.059	1.00
151_Q	164_D	1.055	1.00
209_Q	223_T	1.049	1.00
423_G	444_A	1.049	1.00
23_F	108_R	1.046	1.00
366_E	370_K	1.043	1.00
358_A	422_L	1.043	1.00
88_T	92_K	1.042	1.00
330_V	342_F	1.040	1.00
363_T	366_E	1.040	1.00
205_E	234_L	1.033	1.00
364_E	374_Y	1.031	1.00
378_T	396_M	1.019	1.00
368_K	374_Y	1.019	1.00
367_A	372_I	1.016	1.00
222_F	357_V	1.015	1.00
128_E	133_K	1.015	1.00
58_H	62_V	1.010	1.00
297_V	315_V	1.008	1.00
116_L	279_N	1.004	1.00
83_I	87_R	1.003	1.00
34_I	105_A	1.003	1.00
177_R	263_R	1.003	1.00
362_L	366_E	1.003	1.00
372_I	402_D	1.003	1.00
301_L	331_A	1.002	1.00
279_N	282_A	1.001	1.00
228_K	394_D	1.000	1.00
224_K	228_K	0.998	1.00
357_V	414_V	0.997	1.00
282_A	287_V	0.996	1.00
66_A	69_L	0.993	1.00
24_R	28_L	0.990	1.00
241_V	248_I	0.988	1.00
243_A	248_I	0.982	1.00
243_A	246_D	0.978	1.00
227_S	231_N	0.977	1.00
163_W	167_D	0.977	1.00
346_V	429_I	0.975	1.00
343_D	430_E	0.971	1.00
161_R	266_A	0.971	1.00
433_C	437_D	0.969	1.00
375_E	406_H	0.967	1.00
28_L	333_E	0.963	1.00
178_L	266_A	0.963	1.00
120_T	124_T	0.961	1.00
28_L	336_A	0.959	1.00
277_G	289_V	0.957	1.00
153_P	157_H	0.957	1.00
233_M	262_Q	0.953	1.00
188_L	226_I	0.951	1.00
84_D	172_K	0.951	1.00
177_R	247_G	0.951	1.00
183_G	205_E	0.945	1.00
156_P	159_D	0.945	1.00
423_G	449_H	0.940	1.00
179_L	262_Q	0.940	1.00
66_A	76_F	0.932	1.00
318_P	347_I	0.932	1.00
236_T	260_E	0.931	1.00
87_R	90_K	0.930	1.00
296_R	304_N	0.928	1.00
42_G	46_L	0.926	1.00
30_L	140_N	0.925	1.00
14_A	41_L	0.924	1.00
177_R	202_D	0.922	1.00
287_V	305_V	0.922	1.00
77_G	80_K	0.921	1.00
397_T	413_I	0.921	1.00
218_I	412_A	0.919	1.00
221_V	225_R	0.918	1.00
417_N	420_E	0.917	1.00
378_T	398_K	0.917	1.00
297_V	310_A	0.916	1.00
64_E	229_K	0.912	1.00
226_I	230_F	0.911	1.00
177_R	199_S	0.910	1.00
210_V	234_L	0.909	1.00
406_H	435_A	0.908	1.00
331_A	334_V	0.906	1.00
181_M	271_I	0.900	1.00
111_K	134_T	0.900	1.00
30_L	336_A	0.897	1.00
360_V	429_I	0.895	1.00
181_M	269_V	0.892	1.00
302_R	334_V	0.891	1.00
70_A	85_K	0.891	1.00
119_F	138_F	0.890	1.00
25_C	332_A	0.887	1.00
210_V	232_L	0.886	1.00
39_N	48_V	0.885	1.00
302_R	309_F	0.885	1.00
160_P	243_A	0.882	1.00
103_G	107_G	0.882	1.00
94_I	97_L	0.878	1.00
248_I	267_V	0.877	1.00
225_R	414_V	0.876	1.00
358_A	418_G	0.875	1.00
225_R	229_K	0.872	1.00
289_V	296_R	0.870	1.00
105_A	110_V	0.869	1.00
95_N	99_G	0.869	1.00
178_L	268_L	0.866	1.00
140_N	309_F	0.864	1.00
101_L	105_A	0.862	1.00
163_W	168_A	0.862	1.00
364_E	400_I	0.860	1.00
30_L	139_D	0.859	1.00
118_K	284_K	0.858	1.00
221_V	224_K	0.855	1.00
159_D	167_D	0.855	1.00
231_N	260_E	0.854	1.00
92_K	95_N	0.853	1.00
113_V	134_T	0.852	1.00
195_H	229_K	0.851	1.00
209_Q	365_K	0.850	1.00
408_V	425_I	0.850	1.00
91_E	94_I	0.849	1.00
141_A	308_I	0.849	1.00
63_I	67_K	0.848	1.00
7_T	31_E	0.848	1.00
210_V	223_T	0.845	1.00
285_A	308_I	0.845	1.00
177_R	264_Y	0.843	1.00
8_Q	30_L	0.843	1.00
220_K	224_K	0.842	1.00
76_F	79_P	0.837	1.00
59_V	86_I	0.836	1.00
64_E	67_K	0.835	1.00
14_A	34_I	0.835	1.00
122_A	307_H	0.834	1.00
173_E	266_A	0.833	1.00
45_C	50_C	0.833	1.00
372_I	400_I	0.830	1.00
424_E	427_L	0.830	1.00
330_V	334_V	0.826	1.00
295_I	310_A	0.825	1.00
204_V	233_M	0.824	1.00
287_V	304_N	0.820	1.00
150_I	271_I	0.819	1.00
12_L	280_L	0.817	1.00
187_G	205_E	0.817	1.00
20_S	325_V	0.816	1.00
286_G	305_V	0.816	1.00
10_V	141_A	0.815	1.00
233_M	252_M	0.815	1.00
21_A	332_A	0.813	1.00
225_R	394_D	0.811	1.00
220_K	223_T	0.810	1.00
21_A	328_G	0.809	1.00
99_G	102_A	0.808	1.00
129_G	132_G	0.808	1.00
60_A	196_A	0.806	1.00
181_M	238_V	0.804	1.00
142_I	331_A	0.800	1.00
24_R	27_D	0.799	1.00
167_D	170_E	0.798	1.00
332_A	336_A	0.797	1.00
88_T	172_K	0.794	1.00
428_A	438_I	0.793	1.00
119_F	281_D	0.792	1.00
333_E	338_K	0.791	1.00
25_C	30_L	0.788	1.00
222_F	353_T	0.788	1.00
9_V	332_A	0.788	1.00
275_P	294_F	0.787	1.00
375_E	401_F	0.786	1.00
90_K	94_I	0.785	1.00
90_K	93_V	0.785	1.00
61_K	65_E	0.783	1.00
12_L	125_L	0.779	1.00
180_V	268_L	0.778	1.00
119_F	285_A	0.777	1.00
300_Q	339_K	0.776	1.00
281_D	285_A	0.776	1.00
56_L	87_R	0.776	1.00
89_W	93_V	0.775	1.00
285_A	304_N	0.773	1.00
278_K	283_G	0.773	1.00
36_E	40_T	0.771	1.00
310_A	314_I	0.771	1.00
151_Q	157_H	0.769	1.00
70_A	75_V	0.768	1.00
218_I	357_V	0.767	1.00
93_V	97_L	0.761	1.00
121_G	125_L	0.761	1.00
96_Q	388_I	0.761	1.00
204_V	236_T	0.760	1.00
57_L	193_V	0.760	1.00
26_A	110_V	0.759	1.00
84_D	88_T	0.759	1.00
105_A	112_V	0.758	1.00
402_D	409_I	0.758	1.00
430_E	440_L	0.757	1.00
154_F	157_H	0.754	1.00
58_H	61_K	0.753	1.00
118_K	279_N	0.751	1.00
294_F	319_M	0.750	1.00
24_R	332_A	0.747	1.00
53_S	57_L	0.742	1.00
122_A	286_G	0.742	1.00
59_V	89_W	0.741	1.00
226_I	232_L	0.741	1.00
301_L	334_V	0.733	1.00
30_L	335_I	0.732	1.00
282_A	285_A	0.728	1.00
101_L	104_M	0.727	1.00
407_R	434_D	0.725	1.00
202_D	264_Y	0.725	1.00
35_V	115_G	0.723	1.00
303_T	310_A	0.722	1.00
75_V	79_P	0.721	1.00
363_T	412_A	0.720	1.00
207_F	212_P	0.719	1.00
241_V	250_V	0.719	1.00
209_Q	220_K	0.718	1.00
151_Q	269_V	0.717	1.00
69_L	72_H	0.715	1.00
360_V	426_G	0.715	1.00
180_V	187_G	0.714	1.00
152_L	269_V	0.711	1.00
323_K	347_I	0.708	1.00
285_A	289_V	0.707	1.00
185_I	351_A	0.707	1.00
150_I	153_P	0.706	1.00
236_T	253_E	0.705	1.00
67_K	78_E	0.704	1.00
154_F	238_V	0.703	1.00
123_N	305_V	0.703	1.00
123_N	137_N	0.703	1.00
208_D	216_K	0.702	1.00
141_A	307_H	0.701	1.00
193_V	197_L	0.698	1.00
129_G	133_K	0.698	1.00
277_G	314_I	0.697	1.00
302_R	305_V	0.694	1.00
85_K	89_W	0.692	1.00
11_V	18_G	0.692	1.00
433_C	438_I	0.691	1.00
69_L	76_F	0.691	1.00
367_A	409_I	0.690	1.00
425_I	429_I	0.690	1.00
301_L	330_V	0.690	1.00
64_E	196_A	0.690	1.00
191_G	230_F	0.689	1.00
28_L	338_K	0.685	1.00
99_G	103_G	0.685	1.00
326_H	329_H	0.685	1.00
21_A	331_A	0.685	1.00
215_D	412_A	0.684	1.00
66_A	74_I	0.683	1.00
7_T	10_V	0.682	1.00
42_G	45_C	0.681	1.00
248_I	266_A	0.678	1.00
427_L	433_C	0.678	1.00
346_V	430_E	0.675	1.00
8_Q	33_V	0.675	1.00
211_I	222_F	0.674	1.00
214_A	357_V	0.672	1.00
401_F	435_A	0.672	1.00
152_L	157_H	0.672	1.00
399_L	455_A	0.672	1.00
411_G	429_I	0.671	1.00
238_V	250_V	0.670	1.00
437_D	440_L	0.670	1.00
95_N	98_T	0.670	1.00
413_I	421_L	0.669	1.00
157_H	269_V	0.667	1.00
408_V	429_I	0.667	1.00
39_N	114_N	0.666	1.00
297_V	301_L	0.666	1.00
221_V	396_M	0.666	1.00
60_A	63_I	0.666	1.00
47_N	98_T	0.665	1.00
83_I	86_I	0.665	1.00
326_H	342_F	0.665	1.00
191_G	203_V	0.663	1.00
380_P	383_A	0.661	1.00
11_V	22_A	0.660	1.00
196_A	354_E	0.660	1.00
53_S	190_M	0.659	1.00
115_G	131_N	0.655	1.00
129_G	134_T	0.655	1.00
282_A	289_V	0.654	1.00
84_D	87_R	0.654	1.00
435_A	439_A	0.654	1.00
427_L	441_T	0.654	1.00
64_E	68_A	0.652	1.00
381_W	451_S	0.652	1.00
187_G	206_M	0.651	1.00
371_G	374_Y	0.651	1.00
356_E	448_L	0.649	1.00
420_E	449_H	0.648	1.00
356_E	417_N	0.648	1.00
171_L	266_A	0.646	1.00
90_K	170_E	0.643	1.00
192_T	229_K	0.638	0.99
327_E	344_P	0.637	0.99
122_A	285_A	0.637	0.99
393_A	416_T	0.636	0.99
377_A	455_A	0.636	0.99
400_I	403_K	0.635	0.99
175_P	199_S	0.634	0.99
188_L	210_V	0.632	0.99
205_E	212_P	0.630	0.99
103_G	106_K	0.630	0.99
206_M	212_P	0.629	0.99
88_T	91_E	0.628	0.99
66_A	79_P	0.627	0.99
427_L	438_I	0.625	0.99
57_L	61_K	0.624	0.99
345_K	370_K	0.623	0.99
25_C	335_I	0.622	0.99
145_A	280_L	0.622	0.99
122_A	308_I	0.621	0.99
91_E	170_E	0.620	0.99
166_T	273_R	0.619	0.99
386_R	389_A	0.619	0.99
427_L	431_M	0.619	0.99
97_L	388_I	0.619	0.99
100_G	104_M	0.618	0.99
377_A	401_F	0.616	0.99
26_A	32_T	0.615	0.99
62_V	69_L	0.615	0.99
438_I	456_A	0.614	0.99
25_C	32_T	0.613	0.99
59_V	72_H	0.611	0.99
287_V	308_I	0.611	0.99
81_T	86_I	0.608	0.99
445_H	450_E	0.607	0.99
346_V	426_G	0.607	0.99
147_S	273_R	0.606	0.99
36_E	112_V	0.606	0.99
68_A	391_D	0.605	0.99
192_T	226_I	0.604	0.99
289_V	295_I	0.604	0.99
385_G	389_A	0.604	0.99
415_G	418_G	0.603	0.99
75_V	78_E	0.600	0.99
65_E	68_A	0.598	0.99
385_G	388_I	0.597	0.99
144_A	311_I	0.594	0.99
192_T	196_A	0.593	0.99
405_S	432_G	0.593	0.99
333_E	337_G	0.593	0.99
374_Y	409_I	0.591	0.99
127_V	136_I	0.591	0.99
19_Y	34_I	0.590	0.99
40_T	48_V	0.590	0.99
153_P	158_E	0.588	0.99
411_G	452_V	0.587	0.99
157_H	164_D	0.587	0.99
309_F	335_I	0.586	0.99
86_I	197_L	0.586	0.99
151_Q	156_P	0.585	0.99
58_H	65_E	0.585	0.99
229_K	354_E	0.583	0.99
311_I	328_G	0.583	0.99
362_L	372_I	0.582	0.99
89_W	92_K	0.580	0.99
218_I	221_V	0.580	0.99
177_R	195_H	0.579	0.99
194_Y	199_S	0.577	0.99
329_H	333_E	0.577	0.99
23_F	27_D	0.577	0.99
17_A	144_A	0.573	0.99
35_V	113_V	0.572	0.99
291_D	296_R	0.569	0.99
50_C	56_L	0.567	0.99
93_V	96_Q	0.567	0.99
188_L	232_L	0.567	0.99
149_P	165_S	0.565	0.99
386_R	390_S	0.563	0.99
333_E	339_K	0.563	0.99
214_A	351_A	0.562	0.99
87_R	172_K	0.562	0.99
401_F	406_H	0.560	0.99
165_S	273_R	0.560	0.99
25_C	336_A	0.560	0.99
37_R	276_N	0.559	0.99
411_G	422_L	0.559	0.99
50_C	54_K	0.558	0.99
350_I	358_A	0.557	0.99
157_H	241_V	0.556	0.99
326_H	453_G	0.555	0.99
131_N	134_T	0.555	0.99
408_V	411_G	0.554	0.99
436_E	440_L	0.553	0.99
202_D	262_Q	0.553	0.99
142_I	332_A	0.553	0.99
381_W	448_L	0.553	0.99
61_K	354_E	0.552	0.99
128_E	132_G	0.551	0.98
235_E	255_K	0.551	0.98
211_I	351_A	0.549	0.98
430_E	441_T	0.548	0.98
71_E	391_D	0.548	0.98
199_S	265_D	0.547	0.98
421_L	448_L	0.544	0.98
241_V	269_V	0.544	0.98
323_K	327_E	0.544	0.98
426_G	430_E	0.544	0.98
122_A	125_L	0.543	0.98
120_T	284_K	0.541	0.98
63_I	74_I	0.540	0.98
205_E	238_V	0.539	0.98
57_L	60_A	0.538	0.98
58_H	390_S	0.538	0.98
181_M	204_V	0.538	0.98
102_A	105_A	0.538	0.98
185_I	349_S	0.537	0.98
42_G	47_N	0.534	0.98
26_A	31_E	0.534	0.98
316_G	319_M	0.533	0.98
171_L	194_Y	0.533	0.98
90_K	97_L	0.531	0.98
84_D	173_E	0.530	0.98
111_K	114_N	0.530	0.98
365_K	368_K	0.530	0.98
33_V	111_K	0.529	0.98
51_I	385_G	0.528	0.98
374_Y	403_K	0.527	0.98
219_V	223_T	0.526	0.98
102_A	112_V	0.524	0.98
294_F	316_G	0.523	0.98
395_G	413_I	0.523	0.98
362_L	410_G	0.523	0.98
326_H	330_V	0.523	0.98
80_K	83_I	0.523	0.98
74_I	81_T	0.523	0.98
359_W	412_A	0.522	0.98
204_V	264_Y	0.521	0.98
155_I	158_E	0.521	0.98
424_E	449_H	0.521	0.98
34_I	110_V	0.521	0.98
9_V	335_I	0.520	0.98
28_L	332_A	0.520	0.98
6_K	31_E	0.518	0.98
399_L	408_V	0.517	0.98
279_N	283_G	0.517	0.98
97_L	101_L	0.517	0.98
315_V	327_E	0.516	0.98
380_P	396_M	0.516	0.98
187_G	270_A	0.516	0.98
453_G	457_E	0.515	0.98
40_T	98_T	0.514	0.98
149_P	166_T	0.513	0.98
295_I	303_T	0.513	0.98
392_C	416_T	0.513	0.98
113_V	127_V	0.513	0.98
427_L	443_H	0.512	0.98
165_S	186_I	0.512	0.98
206_M	271_I	0.512	0.98
247_G	265_D	0.510	0.98
426_G	441_T	0.510	0.98
157_H	162_I	0.510	0.98
190_M	268_L	0.508	0.97
372_I	407_R	0.508	0.97
27_D	108_R	0.508	0.97
387_A	448_L	0.507	0.97
217_D	396_M	0.506	0.97
119_F	128_E	0.506	0.97
231_N	234_L	0.504	0.97
190_M	193_V	0.501	0.97
41_L	102_A	0.500	0.97
354_E	416_T	0.500	0.97

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1ojtA	2	0.9895	100	0.207	Contact Map
3ladA	2	0.9768	100	0.213	Contact Map
4jq9A	3	0.9916	100	0.215	Contact Map
3ic9A	2	0.9831	100	0.229	Contact Map
3urhA	2	0.9641	100	0.231	Contact Map
1zmdA	4	0.981	100	0.231	Contact Map
2qaeA	2	0.9684	100	0.235	Contact Map
1dxlA	2	0.9747	100	0.243	Contact Map
1lvlA	2	0.9578	100	0.243	Contact Map
2eq6A	2	0.9641	100	0.243	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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