CYSE - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

CYSE - Serine acetyltransferase

UniProt:	P0A9D4	Sequences: MSCEELEIVWNNIKAEARTLADCEPMLASFYHATLLKHENLGSALSYMLANKLSSPIMPAIAIREVVEEAYAADPEMIASAACDIQAVRTRDPAVDKYSTPLLYLKGFHALQAYRIGHWLWNQGRRALAIFLQNQVSVTFQVDIHPAAKIGRGIMLDHATGIVVGETAVIENDVSILQSVTLGGTGKSGGDRHPKIREGVMIGAGAKILGNIEVGRGAKIGAGSVVLQPVPPHTTAAGVPARIVGKPDSDKPSMDMDQHFNGINHTFEYGDGI	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10187
Length:	273 (241)
Sequences:	982 (603)
Seq/√Len:	38.8

ECOLI - CYSE
BACSU - CYSE

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
142_V	159_A	5.436	1.00
171_E	197_R	4.785	1.00
197_R	213_E	4.665	1.00
196_I	214_V	4.302	1.00
171_E	198_E	3.952	1.00
152_R	172_N	3.903	1.00
197_R	216_R	3.838	1.00
156_L	162_I	3.679	1.00
191_D	195_K	3.539	1.00
195_K	211_N	3.255	1.00
172_N	198_E	3.215	1.00
171_E	213_E	3.043	1.00
221_G	237_A	2.917	1.00
196_I	202_I	2.605	1.00
14_K	18_R	2.528	1.00
150_I	170_I	2.479	1.00
213_E	229_P	2.421	1.00
164_V	170_I	2.358	1.00
202_I	220_I	2.279	1.00
234_T	243_I	2.215	0.99
42_G	82_A	2.210	0.99
13_I	102_L	2.190	0.99
70_A	119_W	2.146	0.99
150_I	164_V	2.064	0.99
217_G	233_H	2.064	0.99
18_R	22_D	2.032	0.99
173_D	199_G	1.950	0.99
191_D	211_N	1.931	0.98
114_Y	150_I	1.921	0.98
231_P	243_I	1.908	0.98
173_D	198_E	1.870	0.98
114_Y	133_Q	1.860	0.98
161_G	179_S	1.856	0.98
121_W	145_H	1.853	0.98
41_L	81_A	1.798	0.97
150_I	154_I	1.789	0.97
199_G	217_G	1.743	0.97
153_G	173_D	1.740	0.97
83_C	152_R	1.689	0.96
113_A	132_L	1.672	0.96
179_S	205_G	1.658	0.96
216_R	233_H	1.656	0.96
198_E	216_R	1.628	0.95
218_A	232_P	1.608	0.95
148_A	178_Q	1.587	0.95
45_L	81_A	1.584	0.95
95_V	105_L	1.575	0.95
216_R	232_P	1.571	0.94
169_V	195_K	1.545	0.94
118_H	122_N	1.542	0.94
78_I	82_A	1.520	0.93
125_R	129_A	1.517	0.93
141_Q	155_M	1.496	0.93
230_V	236_A	1.489	0.93
179_S	207_K	1.479	0.92
207_K	225_V	1.461	0.92
202_I	208_I	1.459	0.92
151_G	172_N	1.457	0.92
78_I	81_A	1.422	0.91
41_L	45_L	1.410	0.91
238_G	241_A	1.406	0.90
89_R	116_I	1.396	0.90
171_E	216_R	1.361	0.89
15_A	18_R	1.360	0.89
79_A	152_R	1.352	0.89
71_Y	77_M	1.350	0.89
113_A	136_V	1.310	0.87
233_H	247_P	1.302	0.87
8_I	82_A	1.300	0.87
42_G	78_I	1.294	0.86
114_Y	136_V	1.282	0.86
55_S	134_N	1.241	0.84
135_Q	138_V	1.199	0.82
93_P	177_L	1.196	0.82
83_C	153_G	1.192	0.81
80_S	83_C	1.182	0.81
168_A	182_L	1.153	0.79
73_A	123_Q	1.152	0.79
147_A	166_E	1.147	0.79
85_I	98_Y	1.144	0.79
77_M	80_S	1.139	0.78
103_L	204_A	1.122	0.77
13_I	99_S	1.118	0.77
31_Y	132_L	1.114	0.77
111_L	154_I	1.112	0.77
144_I	164_V	1.112	0.77
236_A	242_R	1.106	0.76
88_V	108_F	1.106	0.76
87_A	91_R	1.104	0.76
73_A	119_W	1.100	0.76
17_A	93_P	1.089	0.75
168_A	204_A	1.082	0.75
197_R	229_P	1.079	0.74
101_P	105_L	1.061	0.73
67_V	116_I	1.054	0.73
135_Q	139_T	1.046	0.72
187_K	195_K	1.028	0.71
174_V	202_I	1.025	0.70
111_L	170_I	1.024	0.70
207_K	237_A	1.015	0.70
70_A	74_D	1.009	0.69
119_W	123_Q	1.009	0.69
228_Q	233_H	1.006	0.69
97_K	100_T	1.001	0.69
161_G	178_Q	0.998	0.68
219_K	247_P	0.998	0.68
156_L	176_I	0.994	0.68
136_V	141_Q	0.978	0.67
125_R	128_L	0.976	0.67
29_S	47_Y	0.967	0.66
100_T	178_Q	0.960	0.65
40_N	43_S	0.958	0.65
142_V	155_M	0.950	0.64
185_T	195_K	0.948	0.64
118_H	149_K	0.947	0.64
69_E	119_W	0.945	0.64
110_A	205_G	0.936	0.63
54_S	57_I	0.932	0.63
149_K	169_V	0.931	0.63
22_D	26_M	0.930	0.63
219_K	235_T	0.929	0.63
195_K	213_E	0.928	0.63
130_I	141_Q	0.919	0.62
155_M	201_M	0.917	0.62
176_I	196_I	0.917	0.62
217_G	247_P	0.907	0.61
91_R	186_G	0.905	0.61
46_S	64_R	0.904	0.61
52_K	55_S	0.899	0.60
208_I	226_V	0.895	0.60
130_I	178_Q	0.895	0.60
227_L	237_A	0.890	0.59
20_L	127_A	0.889	0.59
41_L	49_L	0.882	0.59
49_L	52_K	0.879	0.58
89_R	189_G	0.877	0.58
188_S	195_K	0.862	0.57
20_L	31_Y	0.857	0.56
66_V	125_R	0.855	0.56
27_L	30_F	0.854	0.56
96_D	132_L	0.843	0.55
177_L	184_G	0.840	0.55
234_T	245_G	0.832	0.54
203_G	219_K	0.829	0.54
185_T	211_N	0.829	0.54
80_S	152_R	0.827	0.54
218_A	234_T	0.825	0.54
15_A	19_T	0.824	0.54
70_A	123_Q	0.824	0.54
106_K	137_S	0.823	0.53
9_V	86_Q	0.820	0.53
111_L	156_L	0.819	0.53
167_T	193_H	0.815	0.53
211_N	229_P	0.815	0.53
114_Y	117_G	0.814	0.53
178_Q	197_R	0.810	0.52
47_Y	55_S	0.802	0.52
71_Y	81_A	0.800	0.51
129_A	212_I	0.798	0.51
149_K	208_I	0.794	0.51
48_M	221_G	0.792	0.51
53_L	108_F	0.792	0.51
13_I	17_A	0.782	0.50
79_A	89_R	0.781	0.50
64_R	68_E	0.781	0.50
185_T	191_D	0.779	0.49
73_A	79_A	0.778	0.49
89_R	98_Y	0.773	0.49
70_A	77_M	0.773	0.49
86_Q	98_Y	0.772	0.49
168_A	196_I	0.772	0.49
182_L	193_H	0.771	0.49
43_S	47_Y	0.767	0.48
77_M	118_H	0.766	0.48
12_N	89_R	0.765	0.48
225_V	237_A	0.764	0.48
8_I	89_R	0.764	0.48
67_V	71_Y	0.758	0.48
81_A	138_V	0.756	0.47
86_Q	90_T	0.755	0.47
162_I	178_Q	0.753	0.47
28_A	34_T	0.750	0.47
109_H	212_I	0.750	0.47
29_S	32_H	0.745	0.46
44_A	102_L	0.744	0.46
234_T	246_K	0.743	0.46
96_D	159_A	0.741	0.46
70_A	116_I	0.739	0.46
132_L	211_N	0.737	0.46
231_P	234_T	0.735	0.46
234_T	244_V	0.734	0.45
153_G	186_G	0.728	0.45
198_E	213_E	0.724	0.45
19_T	23_C	0.721	0.44
181_T	193_H	0.719	0.44
52_K	221_G	0.718	0.44
77_M	228_Q	0.718	0.44
8_I	90_T	0.717	0.44
224_S	227_L	0.716	0.44
187_K	211_N	0.715	0.44
21_A	33_A	0.712	0.43
12_N	15_A	0.710	0.43
17_A	99_S	0.709	0.43
174_V	208_I	0.708	0.43
73_A	76_E	0.707	0.43
59_P	62_A	0.706	0.43
207_K	227_L	0.700	0.42
12_N	19_T	0.700	0.42
12_N	16_E	0.696	0.42
124_G	128_L	0.693	0.42
187_K	191_D	0.691	0.42
131_F	141_Q	0.690	0.42
156_L	164_V	0.689	0.41
212_I	229_P	0.689	0.41
191_D	212_I	0.689	0.41
67_V	171_E	0.688	0.41
243_I	246_K	0.684	0.41
71_Y	78_I	0.681	0.41
38_H	47_Y	0.679	0.41
65_E	208_I	0.679	0.41
183_G	192_R	0.674	0.40
138_V	161_G	0.673	0.40
212_I	219_K	0.670	0.40
213_E	216_R	0.662	0.39
46_S	50_A	0.658	0.39
122_N	147_A	0.658	0.39
43_S	59_P	0.657	0.39
230_V	235_T	0.656	0.39
30_F	104_Y	0.654	0.38
59_P	214_V	0.652	0.38
77_M	150_I	0.652	0.38
101_P	221_G	0.651	0.38
178_Q	229_P	0.651	0.38
238_G	242_R	0.650	0.38
212_I	228_Q	0.650	0.38
8_I	11_N	0.649	0.38
12_N	86_Q	0.649	0.38
136_V	179_S	0.649	0.38
76_E	79_A	0.644	0.38
95_V	130_I	0.643	0.37
176_I	200_V	0.641	0.37
232_P	240_P	0.639	0.37
166_E	178_Q	0.639	0.37
72_A	75_P	0.638	0.37
224_S	237_A	0.635	0.37
8_I	248_D	0.633	0.37
225_V	238_G	0.632	0.37
22_D	220_I	0.631	0.36
160_T	179_S	0.631	0.36
184_G	212_I	0.628	0.36
97_K	202_I	0.628	0.36
12_N	130_I	0.628	0.36
27_L	36_L	0.628	0.36
136_V	142_V	0.626	0.36
78_I	244_V	0.624	0.36
174_V	216_R	0.618	0.35
16_E	97_K	0.612	0.35
137_S	160_T	0.612	0.35
73_A	176_I	0.612	0.35
106_K	177_L	0.611	0.35
14_K	123_Q	0.609	0.35
60_A	64_R	0.606	0.34
201_M	245_G	0.602	0.34
160_T	221_G	0.601	0.34
100_T	197_R	0.600	0.34
63_I	66_V	0.599	0.34
85_I	108_F	0.599	0.34
119_W	122_N	0.599	0.34
209_L	222_A	0.599	0.34
214_V	226_V	0.595	0.33
45_L	116_I	0.595	0.33
129_A	211_N	0.593	0.33
41_L	75_P	0.589	0.33
207_K	224_S	0.589	0.33
59_P	220_I	0.589	0.33
200_V	220_I	0.585	0.33
31_Y	48_M	0.585	0.33
76_E	80_S	0.584	0.33
169_V	191_D	0.581	0.32
72_A	79_A	0.580	0.32
87_A	206_A	0.579	0.32
156_L	208_I	0.574	0.32
56_P	60_A	0.573	0.32
126_R	130_I	0.571	0.32
52_K	66_V	0.571	0.32
188_S	211_N	0.570	0.31
174_V	197_R	0.565	0.31
217_G	245_G	0.565	0.31
8_I	12_N	0.562	0.31
46_S	124_G	0.560	0.31
118_H	182_L	0.559	0.31
24_E	125_R	0.559	0.31
148_A	158_H	0.558	0.31
39_E	79_A	0.557	0.30
136_V	236_A	0.556	0.30
156_L	223_G	0.555	0.30
110_A	174_V	0.554	0.30
13_I	134_N	0.553	0.30
29_S	38_H	0.552	0.30
87_A	231_P	0.550	0.30
185_T	212_I	0.550	0.30
72_A	149_K	0.550	0.30
197_R	218_A	0.549	0.30
11_N	19_T	0.548	0.30
169_V	211_N	0.547	0.30
66_V	69_E	0.547	0.30
93_P	157_D	0.546	0.30
59_P	225_V	0.542	0.29
225_V	239_V	0.539	0.29
13_I	30_F	0.539	0.29
239_V	242_R	0.538	0.29
111_L	142_V	0.538	0.29
85_I	102_L	0.538	0.29
114_Y	129_A	0.536	0.29
136_V	150_I	0.535	0.29
113_A	135_Q	0.535	0.29
95_V	221_G	0.534	0.29
91_R	184_G	0.534	0.29
113_A	117_G	0.532	0.29
110_A	134_N	0.532	0.29
128_L	209_L	0.528	0.28
101_P	116_I	0.527	0.28
116_I	136_V	0.526	0.28
88_V	155_M	0.525	0.28
34_T	41_L	0.525	0.28
29_S	61_I	0.525	0.28
65_E	68_E	0.524	0.28
96_D	189_G	0.522	0.28
157_D	192_R	0.520	0.28
95_V	101_P	0.519	0.28
219_K	248_D	0.519	0.28
32_H	37_K	0.519	0.28
166_E	193_H	0.517	0.28
183_G	193_H	0.515	0.27
44_A	53_L	0.513	0.27
95_V	156_L	0.512	0.27
50_A	58_M	0.511	0.27
60_A	63_I	0.511	0.27
69_E	243_I	0.510	0.27
94_A	157_D	0.510	0.27
22_D	80_S	0.510	0.27
15_A	89_R	0.509	0.27
218_A	230_V	0.509	0.27
183_G	209_L	0.509	0.27
9_V	12_N	0.509	0.27
168_A	186_G	0.509	0.27
185_T	213_E	0.508	0.27
230_V	244_V	0.507	0.27
135_Q	211_N	0.507	0.27
113_A	178_Q	0.507	0.27
103_L	109_H	0.506	0.27
91_R	175_S	0.506	0.27
18_R	79_A	0.505	0.27
8_I	221_G	0.504	0.27
118_H	231_P	0.504	0.27
74_D	119_W	0.503	0.27
185_T	238_G	0.503	0.27
69_E	90_T	0.503	0.27
114_Y	148_A	0.501	0.26
175_S	199_G	0.501	0.26
49_L	67_V	0.500	0.26
78_I	88_V	0.500	0.26

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4h7oA	6	0.9451	100	0.385	Contact Map
4n6aA	3	0.8938	100	0.39	Contact Map
1ssqA	6	0.9414	100	0.407	Contact Map
4hzdA	5	0.9084	100	0.443	Contact Map
3q1xA	3	0.8645	100	0.532	Contact Map
3f1xA	6	0.8608	100	0.575	Contact Map
3tk8A	3	0.685	99.9	0.767	Contact Map
3fttA	3	0.6227	99.9	0.77	Contact Map
1krrA	3	0.685	99.9	0.772	Contact Map
3srtA	3	0.63	99.9	0.777	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0089 seconds.