GLNA - ECOLI - GREMLIN Contacts

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GLNA - Glutamine synthetase

UniProt:	P0A9C5	Sequences: MSAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPAHQVNAEFFEEGKMFDGSSIGGWKGINESDMVLMPDASTAVIDPFFADSTLIIRCDILEPGTLQGYDRDPRSIAKRAEDYLRSTGIADTVLFGPEPEFFLFDDIRFGSSISGSHVAIDDIEGAWNSSTQYEGGNKGHRPAVKGGYFPVPPVDSAQDIRSEMCLVMEQMGLVVEAHHHEVATAGQNEVATRFNTMTKKADEIQIYKYVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLSKNGVNLFAGDKYAGLSEQALYYIGGVIKHAKAINALANPTTNSYKRLVPGYEAPVMLAYSARNRSASIRIPVVSSPKARRIEVRFPDPAANPYLCFAALLMAGLDGIKNKIHPGEAMDKNLYDLPPEEAKEIPQVAGSLEEALNELDLDREFLKAGGVFTDEAIDAYIALRREEDDRVRMTPHPVEFELYYSV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10383
Length:	469 (423)
Sequences:	6368 (3189)
Seq/√Len:	155.0

ECOLI - GLNA PUUA
BACSU - GLNA
HALSA - GLNA
SULSO - GLNA Q97VQ9 Q97W07

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
423_D	448_R	5.057	1.00
300_G	387_I	4.680	1.00
195_E	250_F	3.827	1.00
96_G	99_Q	3.827	1.00
273_M	298_Y	3.810	1.00
298_Y	379_G	3.685	1.00
381_D	385_N	3.662	1.00
91_D	110_K	3.473	1.00
115_Y	384_K	3.446	1.00
114_D	118_S	3.372	1.00
119_T	384_K	3.325	1.00
297_Y	386_K	3.276	1.00
94_E	99_Q	3.001	1.00
8_T	12_E	2.924	1.00
304_K	385_N	2.842	1.00
112_A	377_M	2.712	1.00
192_I	196_M	2.699	1.00
134_F	215_A	2.675	1.00
429_L	437_D	2.666	1.00
437_D	441_D	2.626	1.00
460_P	464_E	2.618	1.00
308_A	425_D	2.586	1.00
108_I	439_A	2.581	1.00
114_D	117_R	2.498	1.00
308_A	428_F	2.461	1.00
282_L	294_Q	2.449	1.00
195_E	249_R	2.431	1.00
127_F	372_F	2.423	1.00
243_V	254_A	2.411	1.00
276_S	280_V	2.387	1.00
273_M	375_L	2.363	1.00
9_M	13_H	2.347	1.00
293_E	386_K	2.323	1.00
227_N	231_K	2.297	1.00
227_N	235_E	2.295	1.00
305_H	425_D	2.259	1.00
305_H	381_D	2.255	1.00
420_N	448_R	2.207	1.00
312_L	374_A	2.204	1.00
414_S	417_E	2.187	1.00
231_K	235_E	2.137	1.00
297_Y	300_G	2.135	1.00
416_E	455_R	2.130	1.00
296_L	388_H	2.127	1.00
113_E	230_T	2.105	1.00
117_R	122_A	2.076	1.00
122_A	275_L	2.072	1.00
311_A	422_L	2.068	1.00
313_A	371_C	2.027	1.00
228_T	231_K	1.959	1.00
307_K	409_P	1.954	1.00
135_L	192_I	1.948	1.00
37_H	201_E	1.945	1.00
200_M	242_V	1.892	1.00
136_F	261_M	1.887	1.00
113_E	229_M	1.882	1.00
20_L	90_C	1.874	1.00
203_M	242_V	1.869	1.00
422_L	440_I	1.851	1.00
413_G	417_E	1.812	1.00
196_M	243_V	1.803	1.00
294_Q	383_I	1.781	1.00
421_E	424_L	1.777	1.00
116_L	125_V	1.772	1.00
102_D	438_E	1.769	1.00
453_R	465_L	1.765	1.00
16_K	198_L	1.761	1.00
206_V	225_R	1.761	1.00
293_E	297_Y	1.741	1.00
297_Y	387_I	1.708	1.00
300_G	389_P	1.700	1.00
366_A	371_C	1.678	1.00
276_S	279_G	1.675	1.00
113_E	228_T	1.670	1.00
233_A	372_F	1.650	1.00
134_F	267_S	1.650	1.00
430_K	437_D	1.645	1.00
291_L	295_A	1.643	1.00
312_L	422_L	1.641	1.00
419_L	444_I	1.625	1.00
44_F	72_A	1.606	1.00
239_Y	243_V	1.604	1.00
15_V	77_I	1.595	1.00
305_H	378_A	1.591	1.00
416_E	420_N	1.590	1.00
307_K	421_E	1.577	1.00
423_D	444_I	1.577	1.00
131_P	236_I	1.574	1.00
125_V	376_L	1.556	1.00
199_V	246_V	1.543	1.00
110_K	230_T	1.543	1.00
417_E	420_N	1.536	1.00
74_T	89_R	1.536	1.00
108_I	373_A	1.535	1.00
10_L	36_A	1.530	1.00
69_M	93_L	1.529	1.00
116_L	380_L	1.519	1.00
126_L	226_F	1.503	1.00
427_E	434_V	1.495	1.00
304_K	387_I	1.485	1.00
377_M	434_V	1.480	1.00
199_V	202_Q	1.434	1.00
21_R	87_I	1.419	1.00
112_A	373_A	1.412	1.00
396_N	399_D	1.408	1.00
121_I	282_L	1.401	1.00
297_Y	388_H	1.386	1.00
23_T	237_Q	1.364	1.00
395_K	404_E	1.361	1.00
232_K	235_E	1.358	1.00
224_T	232_K	1.357	1.00
135_L	247_A	1.352	1.00
309_I	313_A	1.352	1.00
87_I	238_I	1.351	1.00
296_L	389_P	1.328	1.00
13_H	84_S	1.325	1.00
426_R	430_K	1.319	1.00
200_M	205_L	1.318	1.00
112_A	115_Y	1.311	1.00
287_K	296_L	1.305	1.00
311_A	419_L	1.303	1.00
310_N	412_A	1.301	1.00
447_R	450_E	1.301	1.00
273_M	379_G	1.286	1.00
359_V	375_L	1.284	1.00
420_N	424_L	1.279	1.00
16_K	201_E	1.273	1.00
5_H	8_T	1.269	1.00
75_A	86_L	1.263	1.00
452_D	455_R	1.257	1.00
10_L	39_V	1.256	1.00
293_E	388_H	1.248	1.00
300_G	390_G	1.248	1.00
420_N	423_D	1.247	1.00
293_E	296_L	1.242	1.00
215_A	265_N	1.229	1.00
137_D	252_K	1.225	1.00
189_A	220_N	1.222	1.00
344_I	357_I	1.212	1.00
104_D	107_S	1.193	1.00
110_K	114_D	1.188	1.00
422_L	428_F	1.186	1.00
298_Y	380_L	1.177	1.00
213_E	221_E	1.172	1.00
314_N	319_S	1.170	1.00
310_N	361_F	1.166	1.00
299_I	357_I	1.165	1.00
308_A	421_E	1.158	1.00
425_D	429_L	1.157	1.00
429_L	440_I	1.157	1.00
51_D	54_S	1.157	1.00
195_E	199_V	1.156	1.00
299_I	344_I	1.155	1.00
115_Y	377_M	1.154	1.00
7_L	40_N	1.148	1.00
423_D	441_D	1.144	1.00
309_I	374_A	1.142	1.00
294_Q	297_Y	1.137	1.00
271_C	375_L	1.130	1.00
307_K	310_N	1.130	1.00
68_L	92_I	1.127	1.00
51_D	55_I	1.123	1.00
29_E	89_R	1.114	1.00
454_V	461_V	1.112	1.00
122_A	276_S	1.107	0.99
135_L	254_A	1.106	0.99
246_V	250_F	1.106	0.99
8_T	11_N	1.103	0.99
257_M	318_N	1.102	0.99
15_V	86_L	1.101	0.99
138_D	248_H	1.100	0.99
49_M	53_S	1.099	0.99
71_D	91_D	1.098	0.99
18_V	39_V	1.090	0.99
227_N	232_K	1.084	0.99
209_A	223_A	1.083	0.99
429_L	441_D	1.082	0.99
309_I	378_A	1.069	0.99
116_L	119_T	1.067	0.99
298_Y	375_L	1.066	0.99
305_H	385_N	1.064	0.99
306_A	343_S	1.061	0.99
217_A	264_D	1.061	0.99
52_G	55_I	1.056	0.99
320_Y	415_L	1.052	0.99
68_L	90_C	1.050	0.99
262_F	458_P	1.048	0.99
285_G	290_G	1.048	0.99
94_E	102_D	1.045	0.99
307_K	417_E	1.041	0.99
50_F	53_S	1.039	0.99
444_I	448_R	1.038	0.99
303_I	344_I	1.037	0.99
242_V	246_V	1.036	0.99
100_G	107_S	1.034	0.99
277_K	280_V	1.031	0.99
48_K	51_D	1.030	0.99
319_S	363_D	1.028	0.99
452_D	456_M	1.024	0.99
6_V	75_A	1.015	0.99
337_A	392_A	1.012	0.99
309_I	428_F	1.006	0.99
321_K	462_E	1.005	0.99
109_A	229_M	0.999	0.99
449_E	453_R	0.999	0.99
311_A	443_Y	0.997	0.99
441_D	445_A	0.994	0.99
6_V	88_I	0.991	0.99
199_V	242_V	0.988	0.99
271_C	371_C	0.987	0.99
247_A	254_A	0.986	0.99
199_V	249_R	0.985	0.99
208_E	225_R	0.982	0.99
121_I	294_Q	0.982	0.99
136_F	255_T	0.980	0.99
62_N	396_N	0.978	0.99
422_L	444_I	0.975	0.99
134_F	265_N	0.973	0.99
76_V	87_I	0.972	0.99
343_S	361_F	0.970	0.99
5_H	9_M	0.969	0.99
451_D	455_R	0.966	0.99
339_N	398_Y	0.965	0.99
34_I	43_F	0.961	0.99
297_Y	383_I	0.955	0.98
49_M	52_G	0.953	0.98
29_E	237_Q	0.950	0.98
7_L	11_N	0.944	0.98
425_D	428_F	0.941	0.98
300_G	388_H	0.939	0.98
312_L	440_I	0.936	0.98
458_P	462_E	0.935	0.98
214_V	265_N	0.934	0.98
6_V	72_A	0.931	0.98
296_L	300_G	0.926	0.98
203_M	238_I	0.921	0.98
258_P	363_D	0.918	0.98
404_E	407_E	0.917	0.98
419_L	447_R	0.916	0.98
180_Y	211_H	0.916	0.98
419_L	451_D	0.915	0.98
221_E	270_H	0.911	0.98
454_V	459_H	0.908	0.98
405_A	408_I	0.906	0.98
224_T	239_Y	0.906	0.98
307_K	333_L	0.903	0.98
73_S	231_K	0.903	0.98
18_V	36_A	0.897	0.98
213_E	270_H	0.897	0.98
60_G	63_E	0.896	0.98
258_P	365_A	0.886	0.98
93_L	100_G	0.886	0.98
192_I	246_V	0.882	0.97
24_D	30_Q	0.882	0.97
449_E	452_D	0.880	0.97
192_I	252_K	0.879	0.97
341_S	397_L	0.878	0.97
283_F	295_A	0.877	0.97
423_D	437_D	0.874	0.97
236_I	269_M	0.873	0.97
302_V	344_I	0.872	0.97
81_F	85_T	0.870	0.97
108_I	112_A	0.867	0.97
317_T	415_L	0.866	0.97
459_H	462_E	0.865	0.97
127_F	232_K	0.864	0.97
416_E	451_D	0.864	0.97
127_F	298_Y	0.862	0.97
275_L	282_L	0.862	0.97
284_A	290_G	0.859	0.97
381_D	430_K	0.852	0.97
419_L	448_R	0.851	0.97
103_R	438_E	0.850	0.97
13_H	77_I	0.849	0.97
316_T	365_A	0.848	0.97
457_T	461_V	0.842	0.97
302_V	357_I	0.842	0.97
334_A	342_A	0.840	0.97
443_Y	447_R	0.839	0.97
334_A	408_I	0.836	0.96
130_E	213_E	0.833	0.96
222_V	239_Y	0.830	0.96
129_P	236_I	0.828	0.96
416_E	448_R	0.827	0.96
312_L	435_F	0.826	0.96
122_A	277_K	0.823	0.96
116_L	121_I	0.821	0.96
448_R	452_D	0.820	0.96
339_N	396_N	0.817	0.96
130_E	221_E	0.816	0.96
125_V	273_M	0.815	0.96
112_A	434_V	0.812	0.96
341_S	398_Y	0.810	0.96
139_I	142_G	0.808	0.96
458_P	461_V	0.802	0.96
273_M	359_V	0.802	0.96
77_I	84_S	0.801	0.96
116_L	275_L	0.801	0.96
104_D	108_I	0.801	0.96
192_I	250_F	0.800	0.96
48_K	54_S	0.800	0.96
119_T	380_L	0.800	0.96
351_S	354_A	0.799	0.95
373_A	435_F	0.799	0.95
121_I	275_L	0.798	0.95
347_P	356_R	0.796	0.95
188_S	248_H	0.796	0.95
190_Q	194_S	0.795	0.95
139_I	143_S	0.794	0.95
423_D	426_R	0.794	0.95
197_C	210_H	0.789	0.95
330_P	360_R	0.787	0.95
38_Q	41_A	0.786	0.95
313_A	425_D	0.785	0.95
306_A	344_I	0.784	0.95
440_I	444_I	0.784	0.95
50_F	54_S	0.781	0.95
332_M	405_A	0.779	0.95
262_F	457_T	0.776	0.95
435_F	440_I	0.775	0.95
93_L	107_S	0.770	0.94
426_R	437_D	0.769	0.94
133_F	196_M	0.769	0.94
191_D	250_F	0.768	0.94
81_F	191_D	0.766	0.94
305_H	308_A	0.764	0.94
71_D	110_K	0.764	0.94
107_S	111_R	0.763	0.94
127_F	233_A	0.762	0.94
310_N	314_N	0.761	0.94
198_L	201_E	0.759	0.94
274_S	356_R	0.758	0.94
334_A	397_L	0.755	0.94
37_H	206_V	0.754	0.94
342_A	397_L	0.752	0.94
113_E	125_V	0.748	0.94
310_N	411_V	0.747	0.94
308_A	427_E	0.743	0.93
205_L	224_T	0.737	0.93
112_A	116_L	0.736	0.93
298_Y	302_V	0.736	0.93
198_L	202_Q	0.734	0.93
119_T	282_L	0.734	0.93
91_D	104_D	0.734	0.93
324_V	331_V	0.730	0.93
195_E	246_V	0.727	0.93
233_A	368_P	0.725	0.93
26_K	446_L	0.725	0.93
130_E	272_H	0.723	0.92
453_R	456_M	0.723	0.92
285_G	288_Y	0.718	0.92
132_E	213_E	0.718	0.92
391_E	394_D	0.717	0.92
317_T	454_V	0.716	0.92
102_D	436_T	0.716	0.92
100_G	110_K	0.716	0.92
49_M	67_V	0.715	0.92
454_V	465_L	0.715	0.92
44_F	47_G	0.714	0.92
48_K	53_S	0.708	0.92
193_R	210_H	0.706	0.92
377_M	428_F	0.703	0.91
214_V	328_E	0.701	0.91
78_D	87_I	0.701	0.91
271_C	372_F	0.700	0.91
17_F	197_C	0.699	0.91
428_F	435_F	0.698	0.91
302_V	359_V	0.698	0.91
325_P	331_V	0.695	0.91
257_M	321_K	0.694	0.91
71_D	74_T	0.694	0.91
442_A	445_A	0.693	0.91
174_P	178_G	0.692	0.91
39_V	88_I	0.692	0.91
275_L	376_L	0.690	0.91
108_I	111_R	0.690	0.91
107_S	110_K	0.689	0.90
99_Q	102_D	0.688	0.90
312_L	443_Y	0.688	0.90
206_V	235_E	0.688	0.90
258_P	319_S	0.687	0.90
200_M	239_Y	0.686	0.90
40_N	45_E	0.686	0.90
326_G	329_A	0.682	0.90
321_K	454_V	0.682	0.90
437_D	440_I	0.680	0.90
258_P	316_T	0.678	0.90
421_E	425_D	0.677	0.90
16_K	83_D	0.677	0.90
381_D	387_I	0.674	0.90
197_C	207_V	0.673	0.89
48_K	52_G	0.671	0.89
428_F	440_I	0.671	0.89
430_K	436_T	0.670	0.89
102_D	107_S	0.665	0.89
128_G	223_A	0.663	0.89
407_E	424_L	0.661	0.89
125_V	275_L	0.660	0.89
289_A	337_A	0.658	0.88
374_A	435_F	0.658	0.88
19_D	31_H	0.656	0.88
297_Y	389_P	0.656	0.88
131_P	224_T	0.655	0.88
381_D	427_E	0.654	0.88
111_R	114_D	0.651	0.88
135_L	196_M	0.651	0.88
17_F	198_L	0.650	0.88
305_H	387_I	0.649	0.88
25_T	439_A	0.649	0.88
305_H	309_I	0.649	0.88
273_M	302_V	0.648	0.88
393_M	397_L	0.647	0.88
454_V	457_T	0.645	0.87
315_P	319_S	0.643	0.87
10_L	18_V	0.642	0.87
82_A	85_T	0.642	0.87
236_I	372_F	0.641	0.87
356_R	360_R	0.641	0.87
335_Y	346_I	0.641	0.87
21_R	29_E	0.640	0.87
340_R	360_R	0.640	0.87
371_C	374_A	0.640	0.87
119_T	386_K	0.639	0.87
94_E	97_T	0.638	0.87
50_F	55_I	0.637	0.87
426_R	429_L	0.637	0.87
317_T	459_H	0.636	0.87
213_E	272_H	0.636	0.87
22_F	68_L	0.634	0.86
113_E	117_R	0.633	0.86
405_A	410_Q	0.632	0.86
136_F	260_P	0.631	0.86
127_F	273_M	0.631	0.86
461_V	465_L	0.630	0.86
13_H	75_A	0.626	0.86
277_K	294_Q	0.625	0.86
240_K	244_H	0.621	0.85
94_E	101_Y	0.619	0.85
306_A	333_L	0.617	0.85
76_V	238_I	0.617	0.85
178_G	181_F	0.616	0.85
187_D	245_N	0.615	0.85
362_P	371_C	0.614	0.85
308_A	426_R	0.614	0.85
302_V	375_L	0.613	0.85
341_S	396_N	0.610	0.84
33_T	81_F	0.610	0.84
266_G	322_R	0.610	0.84
20_L	43_F	0.609	0.84
9_M	75_A	0.609	0.84
384_K	387_I	0.609	0.84
87_I	203_M	0.608	0.84
49_M	54_S	0.608	0.84
116_L	376_L	0.608	0.84
82_A	191_D	0.608	0.84
132_E	270_H	0.608	0.84
39_V	72_A	0.607	0.84
259_K	266_G	0.605	0.84
15_V	84_S	0.602	0.84
315_P	366_A	0.601	0.83
388_H	391_E	0.601	0.83
111_R	115_Y	0.600	0.83
339_N	393_M	0.599	0.83
50_F	181_F	0.599	0.83
135_L	252_K	0.599	0.83
132_E	221_E	0.599	0.83
72_A	88_I	0.599	0.83
422_L	435_F	0.599	0.83
285_G	296_L	0.599	0.83
85_T	194_S	0.596	0.83
261_M	264_D	0.596	0.83
34_I	48_K	0.595	0.83
376_L	380_L	0.594	0.83
308_A	422_L	0.593	0.83
333_L	343_S	0.593	0.83
397_L	405_A	0.592	0.83
131_P	239_Y	0.592	0.83
10_L	15_V	0.591	0.82
330_P	341_S	0.591	0.82
5_H	10_L	0.590	0.82
115_Y	119_T	0.590	0.82
272_H	356_R	0.590	0.82
128_G	211_H	0.589	0.82
43_F	48_K	0.589	0.82
16_K	84_S	0.588	0.82
205_L	238_I	0.588	0.82
336_S	342_A	0.587	0.82
317_T	462_E	0.586	0.82
304_K	308_A	0.586	0.82
304_K	409_P	0.585	0.82
179_G	182_P	0.584	0.82
333_L	409_P	0.583	0.82
9_M	77_I	0.583	0.82
318_N	462_E	0.583	0.82
127_F	229_M	0.583	0.82
275_L	294_Q	0.580	0.81
196_M	222_V	0.580	0.81
80_F	242_V	0.578	0.81
126_L	274_S	0.577	0.81
207_V	222_V	0.576	0.81
200_M	207_V	0.575	0.81
135_L	189_A	0.575	0.81
395_K	398_Y	0.574	0.81
312_L	370_L	0.573	0.80
270_H	358_E	0.573	0.80
53_S	57_G	0.573	0.80
241_Y	245_N	0.573	0.80
79_P	203_M	0.571	0.80
207_V	210_H	0.570	0.80
189_A	252_K	0.570	0.80
54_S	214_V	0.570	0.80
374_A	428_F	0.567	0.80
89_R	238_I	0.565	0.80
380_L	384_K	0.564	0.79
61_I	328_E	0.563	0.79
16_K	202_Q	0.563	0.79
296_L	335_Y	0.563	0.79
184_P	190_Q	0.560	0.79
81_F	194_S	0.560	0.79
285_G	289_A	0.559	0.79
245_N	248_H	0.559	0.79
362_P	366_A	0.558	0.79
78_D	203_M	0.558	0.79
19_D	241_Y	0.557	0.79
301_G	383_I	0.557	0.79
289_A	392_A	0.555	0.78
211_H	214_V	0.555	0.78
56_G	59_K	0.554	0.78
321_K	459_H	0.554	0.78
379_G	382_G	0.553	0.78
306_A	361_F	0.552	0.78
44_F	88_I	0.551	0.78
267_S	364_P	0.551	0.78
426_R	441_D	0.551	0.78
329_A	398_Y	0.550	0.78
313_A	378_A	0.549	0.78
177_K	264_D	0.548	0.77
317_T	451_D	0.547	0.77
109_A	373_A	0.547	0.77
301_G	382_G	0.547	0.77
454_V	462_E	0.546	0.77
287_K	290_G	0.545	0.77
82_A	198_L	0.545	0.77
422_L	425_D	0.544	0.77
246_V	249_R	0.544	0.77
129_P	372_F	0.544	0.77
287_K	293_E	0.543	0.77
194_S	198_L	0.543	0.77
19_D	33_T	0.543	0.77
22_F	92_I	0.542	0.77
205_L	236_I	0.542	0.77
393_M	408_I	0.541	0.77
11_N	14_E	0.540	0.76
205_L	239_Y	0.539	0.76
331_V	410_Q	0.539	0.76
208_E	223_A	0.539	0.76
134_F	264_D	0.537	0.76
39_V	43_F	0.537	0.76
49_M	55_I	0.537	0.76
38_Q	206_V	0.537	0.76
313_A	359_V	0.536	0.76
21_R	238_I	0.535	0.76
134_F	259_K	0.535	0.76
128_G	226_F	0.535	0.76
404_E	408_I	0.534	0.76
226_F	229_M	0.534	0.76
308_A	311_A	0.532	0.75
30_Q	182_P	0.532	0.75
49_M	56_G	0.532	0.75
138_D	253_T	0.531	0.75
454_V	458_P	0.531	0.75
453_R	457_T	0.530	0.75
17_F	81_F	0.530	0.75
397_L	410_Q	0.529	0.75
133_F	222_V	0.529	0.75
129_P	269_M	0.529	0.75
208_E	226_F	0.529	0.75
221_E	358_E	0.527	0.75
340_R	358_E	0.526	0.75
257_M	462_E	0.525	0.74
324_V	327_Y	0.525	0.74
237_Q	366_A	0.525	0.74
214_V	327_Y	0.524	0.74
223_A	356_R	0.522	0.74
226_F	274_S	0.522	0.74
201_E	207_V	0.522	0.74
9_M	14_E	0.521	0.74
453_R	461_V	0.521	0.74
424_L	427_E	0.521	0.74
425_D	437_D	0.520	0.74
414_S	455_R	0.519	0.74
313_A	374_A	0.519	0.74
384_K	430_K	0.519	0.74
6_V	9_M	0.519	0.74
314_N	320_Y	0.518	0.73
317_T	461_V	0.518	0.73
75_A	88_I	0.518	0.73
6_V	13_H	0.518	0.73
175_A	178_G	0.517	0.73
280_V	294_Q	0.516	0.73
196_M	242_V	0.515	0.73
318_N	321_K	0.515	0.73
263_G	456_M	0.514	0.73
111_R	436_T	0.514	0.73
219_Q	267_S	0.514	0.73
385_N	388_H	0.513	0.73
34_I	39_V	0.513	0.73
297_Y	304_K	0.513	0.73
17_F	33_T	0.513	0.73
125_V	229_M	0.513	0.73
118_S	424_L	0.512	0.73
416_E	423_D	0.512	0.73
137_D	175_A	0.511	0.72
281_N	405_A	0.511	0.72
327_Y	456_M	0.510	0.72
128_G	274_S	0.509	0.72
130_E	270_H	0.508	0.72
109_A	230_T	0.508	0.72
377_M	430_K	0.508	0.72
441_D	444_I	0.507	0.72
38_Q	225_R	0.507	0.72
137_D	173_R	0.507	0.72
419_L	423_D	0.507	0.72
180_Y	214_V	0.506	0.72
306_A	309_I	0.506	0.72
11_N	37_H	0.505	0.72
130_E	358_E	0.505	0.72
337_A	394_D	0.505	0.72
205_L	235_E	0.504	0.71
17_F	194_S	0.502	0.71
276_S	282_L	0.501	0.71
130_E	340_R	0.501	0.71
284_A	352_P	0.501	0.71
378_A	382_G	0.500	0.71

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4s17A	5	0.9467	100	0.096	Contact Map
1f52A	5	0.9851	100	0.1	Contact Map
3ng0A	5	0.9787	100	0.102	Contact Map
4acfA	5	0.9893	100	0.108	Contact Map
4lniA	5	0.9275	100	0.111	Contact Map
4hppA	3	0.8593	100	0.165	Contact Map
2j9iA	5	0.8763	100	0.183	Contact Map
3o6xA	3	0.8145	100	0.345	Contact Map
3fkyA	8	0.6951	100	0.359	Contact Map
2ojwA	5	0.7271	100	0.365	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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