GLPA - ECOLI - GREMLIN Contacts

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GLPA - Anaerobic glycerol-3-phosphate dehydrogenase subunit A

UniProt:	P0A9C0	Sequences: MKTRDSQSSDVIIIGGGATGAGIARDCALRGLRVILVERHDIATGATGRNHGLLHSGARYAVTDAESARECISENQILKRIARHCVEPTNGLFITLPEDDLSFQATFIRACEEAGISAEAIDPQQARIIEPAVNPALIGAVKVPDGTVDPFRLTAANMLDAKEHGAVILTAHEVTGLIREGATVCGVRVRNHLTGETQALHAPVVVNAAGIWGQHIAEYADLRIRMFPAKGSLLIMDHRINQHVINRCRKPSDADILVPGDTISLIGTTSLRIDYNEIDDNRVTAEEVDILLREGEKLAPVMAKTRILRAYSGVRPLVASDDDPSGRNVSRGIVLLDHAERDGLDGFITITGGKLMTYRLMAEWATDAVCRKLGNTRPCTTADLALPGSQEPAEVTLRKVISLPAPLRGSAVYRHGDRTPAWLSEGRLHRSLVCECEAVTAGEVQYAVENLNVNSLLDLRRRTRVGMGTCQGELCACRAAGLLQRFNVTTSAQSIEQLSTFLNERWKGVQPIAWGDALRESEFTRWVYQGLCGLEKEQKDAL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10391
Length:	542 (474)
Sequences:	3803 (2515)
Seq/√Len:	115.5

ECOLI - GLPA GLPD
BACSU - GLPD
HALSA - Q9HNS4
SULSO - Q97VT4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
12_I	187_V	5.250	1.00
126_A	140_A	4.595	1.00
9_S	35_I	3.884	1.00
190_R	197_T	3.684	1.00
39_R	173_E	3.666	1.00
37_V	189_V	3.273	1.00
173_E	190_R	3.214	1.00
188_R	199_A	3.206	1.00
161_A	166_A	3.192	1.00
449_E	486_F	3.130	1.00
189_V	200_L	3.055	1.00
285_A	304_K	3.015	1.00
236_M	266_I	2.988	1.00
12_I	202_A	2.949	1.00
107_F	112_E	2.930	1.00
289_D	293_R	2.904	1.00
21_A	158_M	2.881	1.00
176_G	188_R	2.794	1.00
12_I	200_L	2.769	1.00
188_R	197_T	2.762	1.00
37_V	174_V	2.740	1.00
175_T	190_R	2.733	1.00
172_H	189_V	2.722	1.00
22_G	358_Y	2.720	1.00
107_F	111_C	2.708	1.00
8_S	203_P	2.687	1.00
173_E	192_H	2.663	1.00
40_H	44_T	2.619	1.00
193_L	454_N	2.585	1.00
206_V	369_V	2.583	1.00
24_A	34_V	2.512	1.00
232_S	291_L	2.506	1.00
123_P	127_R	2.493	1.00
42_I	170_T	2.458	1.00
9_S	167_V	2.457	1.00
16_G	36_L	2.428	1.00
178_I	186_G	2.416	1.00
289_D	304_K	2.383	1.00
285_A	289_D	2.364	1.00
8_S	201_H	2.308	1.00
108_I	112_E	2.296	1.00
441_A	445_Q	2.250	1.00
35_I	200_L	2.216	1.00
12_I	35_I	2.191	1.00
14_I	216_I	2.185	1.00
12_I	37_V	2.128	1.00
397_L	401_I	2.108	1.00
191_N	194_T	2.070	1.00
209_A	216_I	2.046	1.00
421_A	450_N	1.976	1.00
125_Q	128_I	1.962	1.00
158_M	168_I	1.950	1.00
296_E	302_M	1.942	1.00
396_T	401_I	1.938	1.00
448_V	483_L	1.893	1.00
178_I	199_A	1.867	1.00
13_I	23_I	1.844	1.00
16_G	38_E	1.809	1.00
18_A	157_N	1.809	1.00
441_A	478_R	1.798	1.00
162_K	168_I	1.779	1.00
227_F	272_R	1.779	1.00
418_R	446_Y	1.738	1.00
109_R	112_E	1.726	1.00
11_V	204_V	1.716	1.00
159_L	418_R	1.706	1.00
396_T	400_V	1.701	1.00
414_R	463_T	1.700	1.00
7_Q	33_R	1.699	1.00
175_T	188_R	1.699	1.00
244_V	247_R	1.694	1.00
39_R	279_D	1.678	1.00
73_S	363_E	1.641	1.00
25_R	160_D	1.638	1.00
37_V	187_V	1.633	1.00
42_I	158_M	1.616	1.00
246_N	249_R	1.611	1.00
10_D	203_P	1.611	1.00
177_L	205_V	1.605	1.00
108_I	111_C	1.602	1.00
23_I	206_V	1.589	1.00
122_D	125_Q	1.588	1.00
179_R	182_A	1.584	1.00
19_T	350_I	1.579	1.00
37_V	200_L	1.555	1.00
21_A	154_T	1.547	1.00
448_V	486_F	1.542	1.00
125_Q	129_I	1.538	1.00
189_V	198_Q	1.533	1.00
29_L	380_T	1.529	1.00
169_L	172_H	1.522	1.00
184_V	205_V	1.518	1.00
283_V	310_A	1.517	1.00
113_E	116_I	1.503	1.00
204_V	369_V	1.502	1.00
230_K	271_L	1.501	1.00
23_I	366_T	1.500	1.00
35_I	169_L	1.495	1.00
478_R	481_G	1.484	1.00
178_I	185_C	1.479	1.00
292_L	304_K	1.461	1.00
178_I	188_R	1.449	1.00
404_P	407_L	1.448	1.00
23_I	208_A	1.444	1.00
106_T	110_A	1.439	1.00
348_I	369_V	1.438	1.00
283_V	288_V	1.437	1.00
292_L	302_M	1.435	1.00
350_I	365_A	1.431	1.00
106_T	112_E	1.429	1.00
9_S	33_R	1.426	1.00
43_A	151_F	1.425	1.00
257_L	264_S	1.425	1.00
421_A	424_S	1.421	1.00
460_R	466_G	1.418	1.00
163_E	418_R	1.408	1.00
245_I	249_R	1.407	1.00
220_A	343_G	1.406	1.00
26_D	381_T	1.403	1.00
238_H	262_T	1.402	1.00
32_L	376_T	1.401	1.00
368_A	371_R	1.395	1.00
251_P	254_A	1.394	1.00
204_V	373_L	1.387	1.00
169_L	198_Q	1.374	1.00
172_H	198_Q	1.371	1.00
180_E	186_G	1.365	1.00
447_A	453_V	1.350	1.00
107_F	110_A	1.344	1.00
153_L	355_L	1.340	1.00
288_V	304_K	1.336	1.00
176_G	219_Y	1.335	1.00
190_R	195_G	1.333	1.00
230_K	273_I	1.325	1.00
422_W	442_G	1.324	1.00
119_E	142_K	1.316	1.00
213_G	226_M	1.314	1.00
42_I	168_I	1.313	1.00
216_I	219_Y	1.304	1.00
304_K	307_I	1.303	1.00
160_D	164_H	1.301	1.00
24_A	161_A	1.300	1.00
26_D	30_R	1.297	1.00
29_L	164_H	1.294	1.00
342_D	372_K	1.288	0.99
177_L	219_Y	1.282	0.99
240_I	245_I	1.274	0.99
90_N	144_P	1.267	0.99
277_E	280_D	1.265	0.99
177_L	184_V	1.264	0.99
292_L	296_E	1.260	0.99
456_L	480_A	1.259	0.99
33_R	167_V	1.256	0.99
400_V	420_P	1.254	0.99
135_P	300_P	1.252	0.99
24_A	166_A	1.252	0.99
232_S	271_L	1.251	0.99
43_A	154_T	1.248	0.99
288_V	310_A	1.247	0.99
265_L	311_Y	1.243	0.99
175_T	197_T	1.243	0.99
122_D	126_A	1.237	0.99
29_L	384_L	1.234	0.99
157_N	358_Y	1.232	0.99
105_A	109_R	1.215	0.99
369_V	373_L	1.207	0.99
25_R	157_N	1.207	0.99
11_V	27_C	1.206	0.99
396_T	399_K	1.202	0.99
177_L	216_I	1.202	0.99
27_C	366_T	1.201	0.99
123_P	129_I	1.194	0.99
86_V	146_G	1.191	0.99
241_N	245_I	1.186	0.99
425_E	445_Q	1.184	0.99
90_N	142_K	1.183	0.99
69_R	73_S	1.183	0.99
149_D	414_R	1.181	0.99
445_Q	486_F	1.179	0.99
317_L	354_K	1.177	0.99
96_L	137_L	1.169	0.99
121_I	126_A	1.166	0.99
174_V	187_V	1.165	0.99
123_P	126_A	1.163	0.99
126_A	137_L	1.157	0.99
240_I	248_C	1.155	0.99
16_G	42_I	1.151	0.99
36_L	158_M	1.148	0.99
241_N	246_N	1.145	0.99
295_G	302_M	1.143	0.99
414_R	443_E	1.132	0.99
227_F	319_A	1.130	0.99
186_G	201_H	1.127	0.99
160_D	163_E	1.127	0.99
445_Q	485_R	1.123	0.99
240_I	249_R	1.116	0.99
433_V	441_A	1.115	0.99
92_L	140_A	1.114	0.99
230_K	284_T	1.113	0.99
100_D	103_F	1.097	0.98
363_E	367_D	1.096	0.98
180_E	185_C	1.096	0.98
231_G	315_R	1.093	0.98
237_D	263_I	1.093	0.98
106_T	111_C	1.092	0.98
434_C	438_A	1.085	0.98
119_E	125_Q	1.084	0.98
9_S	12_I	1.079	0.98
397_L	400_V	1.072	0.98
21_A	168_I	1.066	0.98
368_A	372_K	1.066	0.98
460_R	467_M	1.063	0.98
211_I	314_V	1.059	0.98
51_H	258_V	1.058	0.98
26_D	379_C	1.053	0.98
458_D	461_R	1.051	0.98
10_D	32_L	1.046	0.98
273_I	277_E	1.041	0.98
66_E	70_E	1.041	0.98
78_L	86_V	1.041	0.98
241_N	244_V	1.040	0.98
284_T	287_E	1.039	0.98
445_Q	482_L	1.038	0.98
459_L	474_L	1.031	0.98
28_A	166_A	1.031	0.98
470_C	473_E	1.027	0.97
186_G	199_A	1.026	0.97
101_L	139_G	1.023	0.97
63_T	328_N	1.023	0.97
367_D	379_C	1.022	0.97
64_D	67_S	1.021	0.97
348_I	365_A	1.021	0.97
444_V	476_A	1.018	0.97
370_C	376_T	1.017	0.97
242_Q	246_N	1.014	0.97
251_P	255_D	1.013	0.97
326_G	331_R	1.007	0.97
348_I	368_A	1.006	0.97
240_I	246_N	1.006	0.97
235_I	309_R	1.004	0.97
37_V	172_H	1.002	0.97
242_Q	247_R	1.002	0.97
79_K	88_P	1.000	0.97
117_S	121_I	0.999	0.97
418_R	421_A	0.998	0.97
122_D	129_I	0.998	0.97
53_L	147_T	0.995	0.97
250_K	297_K	0.993	0.97
126_A	129_I	0.991	0.97
244_V	248_C	0.989	0.97
40_H	171_A	0.985	0.97
70_E	360_L	0.985	0.97
47_T	154_T	0.983	0.97
245_I	248_C	0.980	0.97
180_E	201_H	0.977	0.97
445_Q	449_E	0.977	0.97
32_L	370_C	0.972	0.96
240_I	247_R	0.969	0.96
242_Q	248_C	0.966	0.96
362_A	379_C	0.962	0.96
390_Q	417_D	0.957	0.96
481_G	485_R	0.957	0.96
87_E	147_T	0.955	0.96
377_R	380_T	0.949	0.96
434_C	437_E	0.945	0.96
204_V	348_I	0.944	0.96
331_R	335_L	0.943	0.96
87_E	413_Y	0.940	0.96
26_D	362_A	0.940	0.96
70_E	364_W	0.938	0.96
476_A	480_A	0.937	0.96
10_D	33_R	0.936	0.96
202_A	205_V	0.934	0.96
240_I	257_L	0.928	0.95
250_K	253_D	0.925	0.95
242_Q	249_R	0.920	0.95
12_I	205_V	0.915	0.95
191_N	196_E	0.912	0.95
409_G	413_Y	0.911	0.95
56_S	143_V	0.910	0.95
18_A	47_T	0.908	0.95
444_V	479_A	0.908	0.95
208_A	350_I	0.907	0.95
429_H	432_L	0.907	0.95
45_G	49_R	0.905	0.95
60_Y	354_K	0.902	0.95
215_H	278_I	0.897	0.95
8_S	33_R	0.896	0.94
204_V	372_K	0.895	0.94
257_L	295_G	0.895	0.94
171_A	454_N	0.891	0.94
82_A	386_L	0.889	0.94
434_C	440_T	0.888	0.94
363_E	382_A	0.883	0.94
441_A	482_L	0.883	0.94
127_R	133_V	0.879	0.94
78_L	153_L	0.878	0.94
46_A	211_I	0.878	0.94
335_L	365_A	0.871	0.94
241_N	249_R	0.868	0.93
326_G	329_V	0.866	0.93
482_L	486_F	0.861	0.93
269_T	315_R	0.859	0.93
106_T	109_R	0.859	0.93
74_E	359_R	0.856	0.93
85_C	156_A	0.855	0.93
36_L	168_I	0.855	0.93
19_T	361_M	0.853	0.93
117_S	120_A	0.850	0.93
51_H	256_I	0.849	0.93
244_V	249_R	0.847	0.93
411_A	440_T	0.846	0.93
40_H	45_G	0.844	0.93
237_D	308_L	0.841	0.92
158_M	170_T	0.840	0.92
243_H	246_N	0.837	0.92
437_E	465_V	0.833	0.92
273_I	314_V	0.829	0.92
187_V	202_A	0.829	0.92
93_F	96_L	0.828	0.92
207_N	213_G	0.826	0.92
192_H	196_E	0.826	0.92
431_S	441_A	0.825	0.92
88_P	93_F	0.825	0.92
126_A	133_V	0.824	0.92
398_R	408_R	0.824	0.92
303_A	306_R	0.824	0.92
373_L	376_T	0.824	0.92
483_L	487_N	0.823	0.92
92_L	126_A	0.821	0.91
59_R	268_T	0.820	0.91
28_A	34_V	0.817	0.91
389_S	392_P	0.815	0.91
263_I	308_L	0.813	0.91
193_L	196_E	0.812	0.91
398_R	401_I	0.809	0.91
411_A	419_T	0.809	0.91
442_G	445_Q	0.809	0.91
98_E	101_L	0.808	0.91
28_A	164_H	0.806	0.91
315_R	354_K	0.806	0.91
124_Q	127_R	0.806	0.91
231_G	269_T	0.806	0.91
350_I	361_M	0.805	0.91
36_L	42_I	0.805	0.91
103_F	107_F	0.805	0.91
480_A	484_Q	0.802	0.90
240_I	244_V	0.800	0.90
425_E	449_E	0.794	0.90
68_A	72_I	0.793	0.90
26_D	363_E	0.793	0.90
426_G	430_R	0.791	0.90
426_G	442_G	0.791	0.90
248_C	257_L	0.790	0.90
89_T	147_T	0.790	0.90
190_R	196_E	0.785	0.90
8_S	184_V	0.784	0.89
250_K	293_R	0.784	0.89
293_R	297_K	0.783	0.89
149_D	260_G	0.782	0.89
325_S	328_N	0.781	0.89
129_I	142_K	0.781	0.89
158_M	162_K	0.780	0.89
156_A	386_L	0.779	0.89
369_V	374_G	0.777	0.89
114_A	117_S	0.777	0.89
446_Y	450_N	0.774	0.89
217_A	349_T	0.773	0.89
162_K	452_N	0.772	0.89
340_E	344_L	0.772	0.89
59_R	354_K	0.772	0.89
439_V	463_T	0.764	0.88
73_S	360_L	0.764	0.88
424_S	427_R	0.764	0.88
477_C	481_G	0.762	0.88
96_L	136_A	0.762	0.88
159_L	162_K	0.761	0.88
177_L	187_V	0.761	0.88
319_A	323_D	0.758	0.88
22_G	362_A	0.758	0.88
154_T	355_L	0.758	0.88
77_I	81_I	0.758	0.88
385_A	389_S	0.757	0.88
233_L	269_T	0.757	0.88
271_L	287_E	0.756	0.88
242_Q	245_I	0.754	0.88
95_T	99_D	0.754	0.88
42_I	452_N	0.753	0.88
439_V	443_E	0.748	0.87
243_H	247_R	0.747	0.87
172_H	200_L	0.746	0.87
124_Q	128_I	0.746	0.87
405_A	409_G	0.745	0.87
230_K	312_S	0.745	0.87
140_A	247_R	0.743	0.87
250_K	254_A	0.743	0.87
256_I	268_T	0.737	0.86
237_D	262_T	0.735	0.86
433_V	444_V	0.733	0.86
121_I	142_K	0.732	0.86
218_E	221_D	0.730	0.86
105_A	108_I	0.730	0.86
23_I	365_A	0.728	0.86
428_L	431_S	0.728	0.86
117_S	123_P	0.727	0.86
84_H	388_G	0.727	0.86
174_V	216_I	0.726	0.86
99_D	102_S	0.725	0.85
233_L	270_S	0.724	0.85
234_L	266_I	0.722	0.85
229_A	317_L	0.721	0.85
23_I	362_A	0.720	0.85
434_C	472_G	0.719	0.85
105_A	111_C	0.716	0.85
81_I	385_A	0.716	0.85
118_A	121_I	0.714	0.85
75_N	86_V	0.709	0.84
391_E	417_D	0.708	0.84
176_G	197_T	0.708	0.84
229_A	272_R	0.708	0.84
29_L	160_D	0.706	0.84
14_I	174_V	0.703	0.84
67_S	71_C	0.700	0.83
22_G	157_N	0.700	0.83
380_T	384_L	0.699	0.83
193_L	455_S	0.699	0.83
145_D	148_V	0.699	0.83
403_L	408_R	0.696	0.83
262_T	468_G	0.696	0.83
27_C	34_V	0.695	0.83
11_V	366_T	0.695	0.83
186_G	202_A	0.694	0.83
363_E	379_C	0.694	0.83
241_N	248_C	0.693	0.83
83_R	389_S	0.692	0.83
116_I	123_P	0.691	0.83
266_I	295_G	0.690	0.83
24_A	168_I	0.690	0.83
53_L	256_I	0.689	0.82
469_T	473_E	0.687	0.82
318_V	322_D	0.687	0.82
161_A	168_I	0.687	0.82
99_D	103_F	0.687	0.82
220_A	345_D	0.686	0.82
161_A	362_A	0.685	0.82
128_I	131_P	0.684	0.82
456_L	459_L	0.684	0.82
388_G	416_G	0.684	0.82
79_K	86_V	0.683	0.82
214_Q	217_A	0.683	0.82
472_G	475_C	0.682	0.82
149_D	261_D	0.681	0.82
124_Q	129_I	0.681	0.82
46_A	60_Y	0.680	0.82
26_D	367_D	0.678	0.81
241_N	247_R	0.677	0.81
370_C	373_L	0.676	0.81
173_E	215_H	0.675	0.81
318_V	334_V	0.674	0.81
425_E	429_H	0.674	0.81
424_S	428_L	0.673	0.81
448_V	453_V	0.673	0.81
54_L	78_L	0.672	0.81
407_L	440_T	0.671	0.81
17_G	20_G	0.671	0.81
271_L	286_E	0.671	0.81
190_R	194_T	0.670	0.81
15_G	20_G	0.664	0.80
325_S	329_V	0.660	0.80
272_R	329_V	0.660	0.80
60_Y	270_S	0.658	0.79
194_T	197_T	0.658	0.79
89_T	244_V	0.657	0.79
121_I	129_I	0.657	0.79
163_E	387_P	0.654	0.79
57_G	60_Y	0.653	0.79
120_A	139_G	0.650	0.79
192_H	195_G	0.649	0.79
335_L	340_E	0.649	0.79
252_S	255_D	0.649	0.79
367_D	381_T	0.648	0.78
22_G	26_D	0.647	0.78
407_L	438_A	0.645	0.78
408_R	419_T	0.644	0.78
66_E	364_W	0.644	0.78
90_N	95_T	0.642	0.78
84_H	389_S	0.642	0.78
459_L	479_A	0.641	0.78
11_V	34_V	0.640	0.78
475_C	478_R	0.640	0.78
175_T	219_Y	0.637	0.77
127_R	134_N	0.637	0.77
251_P	268_T	0.636	0.77
360_L	364_W	0.636	0.77
37_V	169_L	0.635	0.77
456_L	479_A	0.635	0.77
425_E	442_G	0.634	0.77
422_W	425_E	0.633	0.77
315_R	353_G	0.632	0.77
164_H	384_L	0.632	0.77
25_R	29_L	0.631	0.77
433_V	475_C	0.631	0.77
419_T	423_L	0.629	0.76
236_M	302_M	0.627	0.76
152_R	451_L	0.625	0.76
253_D	256_I	0.625	0.76
235_I	265_L	0.624	0.76
428_L	445_Q	0.622	0.76
213_G	351_T	0.621	0.75
251_P	256_I	0.619	0.75
123_P	128_I	0.618	0.75
13_I	366_T	0.618	0.75
30_R	367_D	0.618	0.75
71_C	357_T	0.614	0.75
273_I	281_N	0.613	0.75
283_V	287_E	0.612	0.74
121_I	125_Q	0.612	0.74
33_R	203_P	0.612	0.74
149_D	152_R	0.611	0.74
333_I	340_E	0.611	0.74
339_A	344_L	0.606	0.74
232_S	287_E	0.606	0.74
255_D	294_E	0.606	0.74
484_Q	487_N	0.605	0.74
470_C	474_L	0.605	0.74
287_E	357_T	0.605	0.74
269_T	354_K	0.603	0.73
243_H	249_R	0.603	0.73
80_R	383_D	0.603	0.73
340_E	372_K	0.602	0.73
436_C	475_C	0.601	0.73
27_C	32_L	0.600	0.73
11_V	206_V	0.600	0.73
57_G	231_G	0.598	0.73
476_A	479_A	0.598	0.73
111_C	118_A	0.596	0.72
194_T	376_T	0.596	0.72
260_G	468_G	0.595	0.72
340_E	343_G	0.595	0.72
60_Y	317_L	0.594	0.72
177_L	347_F	0.593	0.72
270_S	354_K	0.592	0.72
269_T	317_L	0.592	0.72
320_S	329_V	0.592	0.72
68_A	317_L	0.590	0.72
102_S	111_C	0.588	0.71
50_N	150_P	0.586	0.71
181_G	184_V	0.585	0.71
215_H	219_Y	0.585	0.71
247_R	254_A	0.583	0.71
104_Q	108_I	0.583	0.71
47_T	150_P	0.583	0.71
231_G	354_K	0.582	0.71
160_D	390_Q	0.582	0.71
366_T	379_C	0.581	0.71
215_H	218_E	0.581	0.71
285_A	288_V	0.580	0.70
174_V	219_Y	0.579	0.70
395_V	405_A	0.577	0.70
225_R	319_A	0.577	0.70
104_Q	107_F	0.577	0.70
426_G	432_L	0.575	0.70
214_Q	224_I	0.575	0.70
316_P	354_K	0.574	0.70
330_S	334_V	0.574	0.70
434_C	475_C	0.572	0.69
60_Y	231_G	0.572	0.69
271_L	284_T	0.569	0.69
102_S	108_I	0.568	0.69
13_I	220_A	0.566	0.69
364_W	367_D	0.565	0.68
9_S	200_L	0.564	0.68
148_V	154_T	0.563	0.68
118_A	123_P	0.563	0.68
436_C	439_V	0.562	0.68
400_V	427_R	0.561	0.68
13_I	25_R	0.561	0.68
46_A	317_L	0.561	0.68
109_R	118_A	0.560	0.68
342_D	368_A	0.559	0.68
456_L	476_A	0.559	0.68
164_H	380_T	0.558	0.68
52_G	150_P	0.558	0.68
227_F	329_V	0.557	0.67
214_Q	218_E	0.557	0.67
329_V	333_I	0.557	0.67
423_L	427_R	0.556	0.67
425_E	450_N	0.556	0.67
56_S	60_Y	0.555	0.67
156_A	387_P	0.554	0.67
52_G	59_R	0.554	0.67
122_D	127_R	0.552	0.67
177_L	185_C	0.552	0.67
435_E	438_A	0.552	0.67
76_Q	88_P	0.551	0.67
101_L	105_A	0.551	0.67
358_Y	381_T	0.551	0.67
56_S	61_A	0.550	0.66
220_A	347_F	0.549	0.66
260_G	355_L	0.548	0.66
248_C	294_E	0.547	0.66
178_I	184_V	0.546	0.66
475_C	479_A	0.545	0.66
184_V	347_F	0.544	0.66
194_T	454_N	0.544	0.66
419_T	422_W	0.544	0.66
217_A	347_F	0.544	0.66
134_N	137_L	0.544	0.66
439_V	444_V	0.543	0.65
178_I	187_V	0.541	0.65
432_L	445_Q	0.540	0.65
229_A	270_S	0.540	0.65
240_I	243_H	0.540	0.65
168_I	172_H	0.539	0.65
465_V	472_G	0.538	0.65
120_A	123_P	0.538	0.65
95_T	141_V	0.538	0.65
398_R	405_A	0.536	0.64
263_I	468_G	0.535	0.64
54_L	356_M	0.535	0.64
459_L	476_A	0.535	0.64
422_W	426_G	0.534	0.64
286_E	289_D	0.533	0.64
88_P	91_G	0.533	0.64
59_R	256_I	0.531	0.64
55_H	59_R	0.530	0.64
395_V	402_S	0.530	0.64
59_R	317_L	0.530	0.64
177_L	186_G	0.529	0.63
34_V	166_A	0.528	0.63
444_V	453_V	0.528	0.63
294_E	297_K	0.528	0.63
257_L	299_A	0.527	0.63
56_S	59_R	0.527	0.63
54_L	355_L	0.527	0.63
360_L	363_E	0.526	0.63
25_R	28_A	0.526	0.63
234_L	288_V	0.526	0.63
480_A	483_L	0.525	0.63
87_E	93_F	0.524	0.63
410_S	439_V	0.524	0.63
427_R	430_R	0.524	0.63
28_A	161_A	0.524	0.63
92_L	129_I	0.523	0.63
341_R	344_L	0.523	0.63
55_H	354_K	0.521	0.62
90_N	93_F	0.521	0.62
75_N	356_M	0.521	0.62
238_H	243_H	0.520	0.62
362_A	366_T	0.520	0.62
30_R	381_T	0.520	0.62
340_E	345_D	0.519	0.62
269_T	287_E	0.519	0.62
51_H	247_R	0.518	0.62
95_T	101_L	0.518	0.62
46_A	354_K	0.517	0.62
52_G	151_F	0.517	0.62
45_G	214_Q	0.517	0.62
423_L	426_G	0.516	0.62
85_C	355_L	0.516	0.62
409_G	428_L	0.515	0.61
428_L	432_L	0.515	0.61
111_C	143_V	0.514	0.61
250_K	302_M	0.514	0.61
477_C	480_A	0.513	0.61
183_T	346_G	0.512	0.61
35_I	189_V	0.512	0.61
400_V	405_A	0.512	0.61
81_I	358_Y	0.512	0.61
420_P	424_S	0.511	0.61
231_G	313_G	0.511	0.61
26_D	29_L	0.511	0.61
102_S	105_A	0.511	0.61
187_V	200_L	0.511	0.61
239_R	308_L	0.510	0.61
134_N	300_P	0.509	0.61
59_R	270_S	0.509	0.61
282_R	286_E	0.509	0.61
404_P	408_R	0.508	0.60
363_E	381_T	0.508	0.60
70_E	74_E	0.508	0.60
95_T	103_F	0.507	0.60
116_I	121_I	0.507	0.60
149_D	464_R	0.507	0.60
188_R	198_Q	0.507	0.60
425_E	432_L	0.507	0.60
353_G	361_M	0.506	0.60
269_T	316_P	0.506	0.60
57_G	354_K	0.506	0.60
426_G	440_T	0.506	0.60
429_H	442_G	0.505	0.60
181_G	449_E	0.505	0.60
414_R	422_W	0.505	0.60
359_R	381_T	0.504	0.60
399_K	402_S	0.504	0.60
437_E	469_T	0.504	0.60
49_R	311_Y	0.504	0.60
105_A	112_E	0.503	0.60
48_G	150_P	0.503	0.60
315_R	331_R	0.503	0.60
222_L	225_R	0.503	0.60
103_F	106_T	0.502	0.59
205_V	346_G	0.502	0.59
9_S	169_L	0.502	0.59
63_T	271_L	0.502	0.59
122_D	128_I	0.501	0.59
118_A	129_I	0.501	0.59
82_A	153_L	0.500	0.59
185_C	201_H	0.500	0.59
55_H	60_Y	0.500	0.59
232_S	307_I	0.500	0.59

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2rghA	2	0.9151	100	0.385	Contact Map
3da1A	1	0.8561	100	0.401	Contact Map
2qcuA	2	0.8856	100	0.424	Contact Map
4h1bA	1	0.6808	100	0.672	Contact Map
4x9mA	1	0.6679	100	0.672	Contact Map
3dmeA	2	0.6421	100	0.683	Contact Map
3axbA	2	0.6808	100	0.693	Contact Map
1y56B	1	0.6734	100	0.695	Contact Map
1pj5A	3	0.9391	100	0.698	Contact Map
1ryiA	4	0.6439	100	0.698	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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