G3P1 - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

G3P1 - Glyceraldehyde-3-phosphate dehydrogenase A

UniProt:	P0A9B2	Sequences: MTIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLLDADYMAYMLKYDSTHGRFDGTVEVKDGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGLFLTDETARKHITAGAKKVVMTGPSKDNTPMFVKGANFDKYAGQDIVSNASCTTNCLAPLAKVINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKVLPELNGKLTGMAFRVPTPNVSVVDLTVRLEKAATYEQIKAAVKAAAEGEMKGVLGYTEDDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLVSWYDNETGYSNKVLDLIAHISK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10367
Length:	331 (326)
Sequences:	5409 (2436)
Seq/√Len:	134.9

ECOLI - G3P1 E4PD G3P3
BACSU - G3P2 G3P1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
163_N	221_E	4.327	1.00
77_E	82_N	3.654	1.00
169_I	248_E	3.465	1.00
160_K	164_D	3.217	1.00
273_G	289_C	3.140	1.00
136_F	328_H	2.817	1.00
203_N	282_T	2.810	1.00
107_R	111_T	2.794	1.00
250_A	304_N	2.740	1.00
79_D	82_N	2.736	1.00
260_V	293_F	2.584	1.00
56_G	68_N	2.549	1.00
166_F	259_A	2.530	1.00
179_T	201_S	2.489	1.00
165_N	262_A	2.443	1.00
4_K	28_E	2.427	1.00
291_S	310_S	2.390	1.00
105_T	108_K	2.337	1.00
145_V	329_I	2.321	1.00
290_T	321_K	2.234	1.00
61_K	71_K	2.223	1.00
231_F	240_V	2.221	1.00
64_H	71_K	2.211	1.00
102_T	105_T	2.182	1.00
170_E	246_R	2.139	1.00
237_N	285_N	2.116	1.00
132_K	136_F	2.079	1.00
256_I	306_V	2.015	1.00
249_K	255_Q	2.004	1.00
178_A	235_T	1.966	1.00
22_Q	54_F	1.957	1.00
46_K	277_D	1.939	1.00
80_P	100_F	1.929	1.00
61_K	64_H	1.912	1.00
238_V	284_F	1.895	1.00
51_H	237_N	1.895	1.00
21_A	29_I	1.882	1.00
40_Y	194_W	1.875	1.00
258_A	262_A	1.863	1.00
216_G	223_N	1.860	1.00
28_E	70_K	1.857	1.00
204_I	231_F	1.848	1.00
159_A	222_L	1.836	1.00
250_A	303_D	1.817	1.00
10_F	45_L	1.808	1.00
103_D	107_R	1.786	1.00
84_K	87_E	1.774	1.00
18_F	29_I	1.772	1.00
116_K	143_D	1.741	1.00
261_K	276_E	1.736	1.00
81_A	111_T	1.731	1.00
81_A	108_K	1.731	1.00
227_T	299_I	1.729	1.00
118_V	326_I	1.710	1.00
274_Y	295_A	1.707	1.00
247_L	306_V	1.688	1.00
321_K	324_D	1.668	1.00
273_G	287_E	1.653	1.00
96_A	120_T	1.650	1.00
18_F	45_L	1.647	1.00
128_P	138_K	1.638	1.00
20_A	320_N	1.631	1.00
159_A	168_I	1.620	1.00
94_A	326_I	1.590	1.00
120_T	322_V	1.590	1.00
18_F	67_V	1.586	1.00
169_I	304_N	1.574	1.00
278_D	296_K	1.564	1.00
169_I	246_R	1.564	1.00
101_L	119_M	1.541	1.00
4_K	89_G	1.538	1.00
257_K	298_G	1.536	1.00
49_S	202_Q	1.534	1.00
73_R	87_E	1.511	1.00
102_T	124_K	1.505	1.00
43_Y	197_G	1.491	1.00
261_K	265_E	1.476	1.00
107_R	110_I	1.449	1.00
64_H	73_R	1.437	1.00
166_F	247_L	1.424	1.00
38_A	74_V	1.418	1.00
49_S	282_T	1.400	1.00
275_T	284_F	1.397	1.00
103_D	127_T	1.396	1.00
53_R	287_E	1.386	1.00
287_E	292_V	1.375	1.00
24_R	327_A	1.370	1.00
158_L	310_S	1.362	1.00
202_Q	236_P	1.353	1.00
23_K	55_D	1.348	1.00
43_Y	194_W	1.334	1.00
275_T	279_V	1.322	1.00
185_T	200_A	1.319	1.00
217_K	223_N	1.317	1.00
158_L	291_S	1.311	1.00
170_E	302_N	1.311	1.00
75_T	88_V	1.309	1.00
181_A	186_V	1.309	1.00
94_A	322_V	1.305	1.00
252_T	255_Q	1.295	1.00
96_A	322_V	1.293	1.00
171_G	226_L	1.290	1.00
162_I	260_V	1.287	1.00
253_Y	298_G	1.286	1.00
261_K	274_Y	1.280	1.00
106_A	119_M	1.279	1.00
196_G	207_S	1.278	1.00
31_A	75_T	1.277	1.00
289_C	292_V	1.246	1.00
199_G	202_Q	1.240	1.00
279_V	284_F	1.233	1.00
246_R	304_N	1.227	1.00
123_S	126_N	1.220	1.00
161_V	272_L	1.214	1.00
79_D	108_K	1.199	1.00
163_N	219_L	1.197	1.00
92_V	326_I	1.195	1.00
83_L	88_V	1.193	1.00
290_T	324_D	1.189	0.99
276_E	295_A	1.182	0.99
161_V	259_A	1.180	0.99
54_F	68_N	1.170	0.99
170_E	304_N	1.168	0.99
193_D	196_G	1.166	0.99
18_F	72_I	1.166	0.99
38_A	60_V	1.157	0.99
162_I	308_L	1.154	0.99
181_A	188_G	1.153	0.99
268_M	272_L	1.145	0.99
165_N	259_A	1.142	0.99
102_T	125_D	1.140	0.99
282_T	285_N	1.127	0.99
184_K	188_G	1.122	0.99
17_V	322_V	1.120	0.99
83_L	112_A	1.114	0.99
158_L	260_V	1.112	0.99
247_L	251_A	1.108	0.99
167_G	247_L	1.106	0.99
16_I	51_H	1.103	0.99
17_V	94_A	1.101	0.99
297_A	309_V	1.090	0.99
17_V	319_S	1.084	0.99
119_M	123_S	1.080	0.99
316_T	320_N	1.079	0.99
165_N	169_I	1.073	0.99
288_V	316_T	1.072	0.99
139_Y	143_D	1.069	0.99
318_Y	322_V	1.066	0.99
104_E	125_D	1.062	0.99
23_K	286_G	1.057	0.99
166_F	251_A	1.056	0.99
61_K	66_I	1.055	0.99
251_A	300_A	1.054	0.99
66_I	69_G	1.049	0.99
176_V	231_F	1.046	0.99
6_G	83_L	1.044	0.99
26_D	327_A	1.038	0.99
47_Y	277_D	1.037	0.99
251_A	255_Q	1.036	0.99
45_L	56_G	1.034	0.99
37_D	40_Y	1.030	0.99
195_R	294_D	1.027	0.99
158_L	308_L	1.026	0.98
300_A	306_V	1.023	0.98
240_V	309_V	1.022	0.98
6_G	90_V	1.019	0.98
139_Y	145_V	1.018	0.98
103_D	126_N	1.012	0.98
63_G	73_R	1.011	0.98
229_M	309_V	1.011	0.98
258_A	261_K	1.009	0.98
138_K	221_E	1.008	0.98
42_A	58_V	1.008	0.98
92_V	118_V	1.007	0.98
123_S	129_M	1.003	0.98
275_T	296_K	1.003	0.98
50_T	236_P	1.000	0.98
41_M	74_V	0.999	0.98
235_T	238_V	0.995	0.98
116_K	139_Y	0.994	0.98
182_T	196_G	0.990	0.98
129_M	217_K	0.990	0.98
66_I	71_K	0.988	0.98
163_N	248_E	0.987	0.98
162_I	247_L	0.981	0.98
253_Y	257_K	0.981	0.98
166_F	256_I	0.970	0.98
155_L	173_M	0.969	0.98
118_V	145_V	0.965	0.98
254_E	258_A	0.964	0.98
264_A	267_E	0.962	0.98
231_F	309_V	0.952	0.98
272_L	291_S	0.942	0.97
288_V	320_N	0.942	0.97
170_E	305_F	0.942	0.97
300_A	303_D	0.941	0.97
131_V	148_A	0.940	0.97
182_T	191_H	0.938	0.97
90_V	93_V	0.932	0.97
161_V	268_M	0.926	0.97
126_N	217_K	0.923	0.97
259_A	262_A	0.921	0.97
274_Y	293_F	0.921	0.97
104_E	107_R	0.920	0.97
50_T	237_N	0.918	0.97
22_Q	70_K	0.916	0.97
162_I	245_V	0.910	0.97
191_H	196_G	0.902	0.97
91_D	115_K	0.901	0.97
286_G	316_T	0.900	0.97
51_H	286_G	0.900	0.97
3_I	27_I	0.897	0.96
251_A	256_I	0.891	0.96
273_G	292_V	0.891	0.96
238_V	285_N	0.891	0.96
154_C	241_V	0.884	0.96
73_R	88_V	0.884	0.96
75_T	84_K	0.884	0.96
251_A	259_A	0.881	0.96
130_F	139_Y	0.879	0.96
132_K	325_L	0.870	0.96
31_A	90_V	0.868	0.96
21_A	323_L	0.866	0.96
275_T	295_A	0.865	0.96
41_M	189_P	0.855	0.95
262_A	267_E	0.854	0.95
51_H	285_N	0.851	0.95
107_R	144_I	0.849	0.95
6_G	112_A	0.840	0.95
132_K	328_H	0.839	0.95
119_M	126_N	0.832	0.95
102_T	108_K	0.829	0.95
181_A	205_I	0.829	0.95
57_T	68_N	0.824	0.94
50_T	186_V	0.823	0.94
34_D	189_P	0.822	0.94
46_K	53_R	0.822	0.94
92_V	329_I	0.820	0.94
257_K	293_F	0.816	0.94
10_F	32_I	0.815	0.94
118_V	325_L	0.814	0.94
60_V	66_I	0.808	0.94
30_V	90_V	0.806	0.94
137_D	267_E	0.805	0.94
132_K	271_V	0.802	0.94
39_D	60_V	0.798	0.93
199_G	236_P	0.798	0.93
31_A	88_V	0.791	0.93
50_T	202_Q	0.786	0.93
262_A	266_G	0.786	0.93
184_K	197_G	0.785	0.93
27_I	327_A	0.780	0.93
32_I	65_L	0.776	0.92
179_T	185_T	0.775	0.92
158_L	293_F	0.773	0.92
36_L	189_P	0.767	0.92
242_D	307_K	0.764	0.92
43_Y	47_Y	0.762	0.92
103_D	144_I	0.760	0.92
172_L	229_M	0.759	0.92
215_V	219_L	0.758	0.91
45_L	54_F	0.757	0.91
101_L	105_T	0.757	0.91
102_T	107_R	0.756	0.91
137_D	328_H	0.756	0.91
99_L	105_T	0.756	0.91
148_A	318_Y	0.753	0.91
17_V	323_L	0.749	0.91
247_L	300_A	0.749	0.91
35_L	189_P	0.747	0.91
84_K	88_V	0.746	0.91
251_A	306_V	0.740	0.90
78_R	99_L	0.740	0.90
75_T	83_L	0.738	0.90
265_E	269_K	0.733	0.90
43_Y	191_H	0.732	0.90
108_K	112_A	0.730	0.90
204_I	309_V	0.729	0.90
165_N	263_A	0.727	0.90
36_L	41_M	0.726	0.90
195_R	297_A	0.725	0.90
108_K	111_T	0.724	0.90
174_T	244_T	0.723	0.89
173_M	241_V	0.722	0.89
46_K	57_T	0.721	0.89
194_W	197_G	0.719	0.89
155_L	159_A	0.719	0.89
31_A	73_R	0.718	0.89
139_Y	328_H	0.718	0.89
50_T	199_G	0.717	0.89
44_M	191_H	0.716	0.89
158_L	241_V	0.714	0.89
229_M	307_K	0.712	0.89
119_M	127_T	0.712	0.89
166_F	249_K	0.712	0.89
123_S	127_T	0.711	0.89
293_F	296_K	0.710	0.89
59_E	66_I	0.710	0.89
42_A	60_V	0.709	0.89
259_A	263_A	0.706	0.88
255_Q	258_A	0.705	0.88
35_L	99_L	0.702	0.88
38_A	42_A	0.700	0.88
184_K	191_H	0.699	0.88
131_V	134_A	0.692	0.87
49_S	236_P	0.690	0.87
215_V	226_L	0.690	0.87
130_F	138_K	0.689	0.87
181_A	184_K	0.688	0.87
266_G	269_K	0.688	0.87
34_D	99_L	0.688	0.87
35_L	41_M	0.687	0.87
245_V	306_V	0.687	0.87
167_G	248_E	0.685	0.87
128_P	140_A	0.684	0.87
261_K	264_A	0.684	0.87
15_R	19_R	0.682	0.87
273_G	291_S	0.682	0.87
27_I	92_V	0.681	0.86
86_D	112_A	0.680	0.86
229_M	299_I	0.678	0.86
245_V	308_L	0.678	0.86
262_A	265_E	0.678	0.86
60_V	64_H	0.677	0.86
7_I	18_F	0.677	0.86
179_T	236_P	0.675	0.86
4_K	91_D	0.673	0.86
35_L	77_E	0.671	0.86
326_I	329_I	0.669	0.85
62_D	66_I	0.668	0.85
208_S	213_K	0.667	0.85
103_D	143_D	0.665	0.85
159_A	226_L	0.664	0.85
128_P	145_V	0.664	0.85
238_V	241_V	0.663	0.85
77_E	83_L	0.661	0.85
32_I	74_V	0.660	0.85
20_A	323_L	0.660	0.85
24_R	320_N	0.659	0.85
302_N	305_F	0.658	0.85
55_D	68_N	0.658	0.85
75_T	87_E	0.657	0.84
22_Q	68_N	0.653	0.84
147_N	319_S	0.651	0.84
58_V	67_V	0.650	0.84
3_I	26_D	0.650	0.84
35_L	78_R	0.647	0.84
118_V	329_I	0.647	0.84
119_M	144_I	0.647	0.84
260_V	272_L	0.644	0.83
96_A	326_I	0.641	0.83
210_G	239_S	0.641	0.83
174_T	231_F	0.640	0.83
23_K	56_G	0.640	0.83
201_S	236_P	0.638	0.83
107_R	143_D	0.633	0.82
247_L	256_I	0.630	0.82
43_Y	279_V	0.629	0.82
57_T	69_G	0.628	0.82
35_L	76_A	0.628	0.82
3_I	92_V	0.625	0.81
244_T	305_F	0.623	0.81
172_L	301_L	0.622	0.81
93_V	114_A	0.622	0.81
132_K	147_N	0.619	0.81
45_L	67_V	0.618	0.81
155_L	241_V	0.617	0.81
39_D	194_W	0.616	0.80
256_I	260_V	0.615	0.80
104_E	111_T	0.615	0.80
130_F	325_L	0.615	0.80
162_I	243_L	0.614	0.80
159_A	219_L	0.611	0.80
260_V	308_L	0.611	0.80
84_K	112_A	0.610	0.80
238_V	279_V	0.607	0.80
165_N	249_K	0.606	0.79
106_A	144_I	0.605	0.79
43_Y	193_D	0.605	0.79
78_R	81_A	0.605	0.79
46_K	58_V	0.604	0.79
6_G	31_A	0.601	0.79
63_G	71_K	0.599	0.79
172_L	227_T	0.599	0.79
176_V	204_I	0.598	0.78
193_D	207_S	0.596	0.78
159_A	243_L	0.596	0.78
3_I	6_G	0.595	0.78
85_W	109_H	0.594	0.78
20_A	24_R	0.592	0.78
35_L	97_T	0.592	0.78
193_D	197_G	0.591	0.78
235_T	284_F	0.590	0.78
246_R	305_F	0.590	0.78
65_L	72_I	0.589	0.77
171_G	245_V	0.589	0.77
202_Q	285_N	0.588	0.77
35_L	83_L	0.588	0.77
6_G	88_V	0.587	0.77
103_D	108_K	0.584	0.77
132_K	324_D	0.583	0.77
88_V	112_A	0.582	0.77
257_K	295_A	0.582	0.77
101_L	106_A	0.579	0.76
204_I	235_T	0.578	0.76
91_D	114_A	0.578	0.76
322_V	326_I	0.576	0.76
110_I	144_I	0.576	0.76
5_V	326_I	0.575	0.76
6_G	89_G	0.574	0.76
215_V	227_T	0.573	0.76
139_Y	329_I	0.573	0.76
204_I	233_V	0.572	0.75
18_F	22_Q	0.572	0.75
154_C	310_S	0.571	0.75
161_V	263_A	0.569	0.75
245_V	260_V	0.569	0.75
148_A	214_A	0.566	0.75
101_L	124_K	0.565	0.75
110_I	143_D	0.564	0.74
5_V	27_I	0.562	0.74
261_K	295_A	0.561	0.74
39_D	62_D	0.559	0.74
194_W	278_D	0.558	0.74
173_M	243_L	0.557	0.73
30_V	33_N	0.556	0.73
175_T	239_S	0.556	0.73
166_F	245_V	0.555	0.73
45_L	58_V	0.554	0.73
24_R	324_D	0.554	0.73
86_D	114_A	0.553	0.73
260_V	274_Y	0.553	0.73
182_T	197_G	0.553	0.73
179_T	202_Q	0.550	0.73
62_D	65_L	0.550	0.73
174_T	307_K	0.550	0.73
173_M	228_G	0.549	0.72
179_T	200_A	0.549	0.72
301_L	305_F	0.548	0.72
38_A	63_G	0.548	0.72
39_D	43_Y	0.547	0.72
40_Y	197_G	0.546	0.72
20_A	316_T	0.546	0.72
174_T	242_D	0.545	0.72
53_R	277_D	0.542	0.71
83_L	109_H	0.540	0.71
164_D	219_L	0.539	0.71
165_N	247_L	0.538	0.71
165_N	267_E	0.537	0.71
32_I	72_I	0.537	0.71
29_I	33_N	0.536	0.71
133_G	271_V	0.536	0.71
264_A	273_G	0.535	0.70
21_A	24_R	0.535	0.70
16_I	316_T	0.535	0.70
91_D	113_G	0.533	0.70
36_L	40_Y	0.533	0.70
251_A	304_N	0.533	0.70
40_Y	189_P	0.533	0.70
277_D	284_F	0.533	0.70
163_N	222_L	0.528	0.69
191_H	197_G	0.525	0.69
6_G	85_W	0.525	0.69
159_A	245_V	0.524	0.69
4_K	30_V	0.522	0.69
171_G	243_L	0.522	0.69
229_M	297_A	0.522	0.69
109_H	114_A	0.521	0.68
38_A	64_H	0.521	0.68
17_V	21_A	0.519	0.68
160_K	267_E	0.516	0.68
147_N	324_D	0.516	0.68
271_V	290_T	0.515	0.68
6_G	75_T	0.513	0.67
8_N	33_N	0.512	0.67
171_G	216_G	0.512	0.67
38_A	61_K	0.512	0.67
254_E	257_K	0.511	0.67
154_C	291_S	0.510	0.67
80_P	83_L	0.508	0.67
325_L	328_H	0.508	0.67
136_F	267_E	0.506	0.66
319_S	324_D	0.505	0.66
318_Y	325_L	0.505	0.66
47_Y	53_R	0.505	0.66
31_A	85_W	0.503	0.66
159_A	163_N	0.502	0.66
166_F	255_Q	0.502	0.66
103_D	125_D	0.500	0.65

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4boyA	4	0.997	100	0.189	Contact Map
3idsC	4	1	100	0.199	Contact Map
4lsmA	4	0.997	100	0.202	Contact Map
3docA	4	0.997	100	0.203	Contact Map
1rm4O	4	0.994	100	0.207	Contact Map
2x5jO	4	0.9758	100	0.211	Contact Map
2ep7A	4	0.9909	100	0.214	Contact Map
3cpsA	4	0.9909	100	0.218	Contact Map
1obfO	4	0.9879	100	0.219	Contact Map
4o59O	4	0.9909	100	0.22	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0108 seconds.