GREMLIN Database
FTNA - Bacterial non-heme ferritin
UniProt: P0A998 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10921
Length: 165 (157)
Sequences: 2279 (1475)
Seq/√Len: 117.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
88_Q142_S3.2961.00
16_L100_K3.2601.00
84_D138_I2.6751.00
3_K111_N2.5681.00
106_H112_Q2.5081.00
109_M117_F2.4541.00
61_L66_N2.3631.00
81_S85_E2.3241.00
31_C86_L2.2471.00
118_N125_S2.2421.00
9_K107_A2.1871.00
14_M61_L2.1831.00
7_I66_N2.1461.00
84_D142_S2.1131.00
90_T134_F2.0351.00
39_A83_L1.9781.00
63_D132_K1.9271.00
132_K136_S1.9081.00
87_F141_L1.8811.00
5_E111_N1.8301.00
56_R122_W1.8241.00
8_E12_E1.7951.00
106_H110_T1.7851.00
10_L57_L1.7751.00
91_Y95_Q1.7551.00
96_L100_K1.7411.00
10_L116_T1.7111.00
89_E92_K1.6861.00
10_L61_L1.6791.00
31_C43_L1.6771.00
32_S40_A1.6451.00
106_H114_Y1.5761.00
65_G135_K1.5691.00
4_P8_E1.5521.00
29_A58_F1.5481.00
22_L70_I1.5481.00
41_A45_R1.5401.00
21_S47_A1.5361.00
43_L90_T1.5181.00
44_R59_D1.5161.00
46_H133_L1.5111.00
71_N75_S1.4911.00
35_T139_D1.4871.00
50_E53_H1.3781.00
77_F89_E1.3601.00
96_L99_Q1.3491.00
32_S37_E1.3271.00
105_A124_V1.3221.00
9_K104_L1.3211.00
18_L54_M1.3211.00
5_E110_T1.3171.00
31_C83_L1.3161.00
24_Y94_E1.3141.00
80_Y89_E1.3041.00
82_S85_E1.2981.00
99_Q103_E1.2440.99
105_A117_F1.2300.99
88_Q92_K1.2210.99
56_R123_Y1.2150.99
84_D141_L1.2100.99
87_F137_I1.2050.99
84_D88_Q1.2010.99
33_Y67_L1.1840.99
85_E88_Q1.1730.99
145_G148_G1.1380.99
39_A154_I1.1210.99
3_K6_M1.1170.99
52_T56_R1.0860.98
10_L60_Y1.0780.98
42_F133_L1.0720.98
42_F134_F1.0590.98
69_R75_S1.0560.98
16_L96_L1.0440.98
92_K95_Q1.0390.98
94_E127_Q1.0360.98
60_Y116_T1.0240.98
30_W34_H1.0230.98
115_P124_V1.0180.97
27_M80_Y1.0170.97
135_K139_D1.0160.97
46_H130_E1.0060.97
77_F85_E1.0010.97
105_A120_L1.0000.97
105_A121_Q0.9980.97
28_S47_A0.9960.97
118_N121_Q0.9930.97
26_Q80_Y0.9920.97
137_I154_I0.9920.97
25_Q55_Q0.9860.97
39_A87_F0.9820.97
17_E127_Q0.9800.97
121_Q125_S0.9700.97
45_R133_L0.9680.97
48_Q51_M0.9630.96
28_S44_R0.9540.96
102_N114_Y0.9340.96
140_K157_E0.9270.96
98_T131_E0.9250.96
87_F138_I0.9200.95
109_M112_Q0.9190.95
43_L86_L0.9190.95
17_E53_H0.9170.95
85_E89_E0.9040.95
15_N71_N0.8990.95
19_Y23_L0.8910.95
72_T75_S0.8830.94
50_E130_E0.8770.94
49_E53_H0.8720.94
6_M116_T0.8720.94
10_L14_M0.8660.94
5_E107_A0.8590.93
30_W86_L0.8550.93
37_E140_K0.8420.93
4_P7_I0.8420.93
45_R48_Q0.8310.92
12_E71_N0.8270.92
20_S97_I0.8220.92
19_Y76_P0.8190.92
7_I61_L0.8160.92
45_R52_T0.8130.91
32_S44_R0.8100.91
18_L22_L0.8060.91
147_S150_G0.8000.91
21_S51_M0.7930.90
97_I100_K0.7890.90
137_I141_L0.7760.89
125_S129_E0.7600.88
18_L25_Q0.7480.88
57_L120_L0.7440.87
8_E69_R0.7410.87
17_E49_E0.7360.87
102_N124_V0.7330.87
4_P81_S0.7310.86
83_L86_L0.7270.86
23_L80_Y0.7260.86
37_E136_S0.7250.86
50_E126_E0.7190.86
58_F62_T0.7120.85
94_E126_E0.7110.85
36_F39_A0.7100.85
43_L137_I0.7090.85
29_A68_P0.7090.85
86_L90_T0.7080.85
64_T113_D0.6990.84
38_G158_L0.6960.84
114_Y117_F0.6940.84
105_A114_Y0.6930.83
51_M55_Q0.6870.83
117_F121_Q0.6870.83
19_Y74_E0.6860.83
60_Y122_W0.6850.83
149_E152_Y0.6800.82
17_E130_E0.6750.82
50_E97_I0.6720.82
35_T136_S0.6710.81
20_S100_K0.6670.81
109_M114_Y0.6660.81
97_I126_E0.6630.81
13_Q17_E0.6630.81
53_H97_I0.6620.81
49_E126_E0.6590.80
13_Q126_E0.6560.80
127_Q130_E0.6520.80
144_A150_G0.6490.79
137_I158_L0.6480.79
107_A111_N0.6370.78
53_H127_Q0.6360.78
67_L79_E0.6350.78
56_R63_D0.6320.77
53_H126_E0.6320.77
80_Y86_L0.6300.77
104_L107_A0.6300.77
38_G41_A0.6200.76
15_N74_E0.6180.76
41_A159_S0.6180.76
63_D118_N0.6130.75
53_H130_E0.6090.75
13_Q50_E0.6090.75
46_H50_E0.6080.75
126_E130_E0.6060.74
153_F156_K0.6060.74
5_E8_E0.6050.74
44_R47_A0.6050.74
48_Q55_Q0.6040.74
91_Y135_K0.5990.74
14_M68_P0.5940.73
12_E16_L0.5930.73
18_L51_M0.5920.73
49_E130_E0.5900.72
19_Y77_F0.5830.72
15_N19_Y0.5820.71
6_M108_A0.5760.71
16_L23_L0.5750.71
57_L119_F0.5740.70
156_K159_S0.5730.70
63_D129_E0.5700.70
152_Y156_K0.5700.70
64_T128_H0.5690.70
43_L134_F0.5650.69
102_N115_P0.5650.69
21_S48_Q0.5630.69
84_D146_K0.5580.68
87_F115_P0.5570.68
88_Q138_I0.5540.68
20_S93_H0.5530.68
60_Y113_D0.5520.67
62_T68_P0.5500.67
55_Q58_F0.5490.67
103_E106_H0.5440.66
95_Q135_K0.5410.66
47_A51_M0.5370.65
31_C39_A0.5370.65
8_E75_S0.5340.65
57_L101_I0.5330.65
48_Q52_T0.5330.65
50_E127_Q0.5320.65
69_R72_T0.5280.64
143_L147_S0.5280.64
99_Q106_H0.5270.64
17_E50_E0.5250.64
13_Q127_Q0.5250.64
71_N74_E0.5240.63
83_L141_L0.5240.63
151_L158_L0.5230.63
8_E71_N0.5220.63
25_Q28_S0.5200.63
22_L128_H0.5200.63
149_E153_F0.5180.63
63_D122_W0.5150.62
154_I157_E0.5120.62
23_L93_H0.5110.62
20_S23_L0.5070.61
24_Y53_H0.5070.61
59_D63_D0.5050.61
43_L87_F0.5000.60
12_E100_K0.5000.60
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1z6oA 3 0.9758 100 0.25 Contact Map
1z6oM 4 0.9879 100 0.264 Contact Map
1vlgA 6 0.9818 100 0.266 Contact Map
3a68A 7 0.9758 100 0.285 Contact Map
3vnxA 6 0.9697 100 0.291 Contact Map
1eumA 6 0.9758 100 0.298 Contact Map
3wnwA 6 0.9758 100 0.299 Contact Map
1s3qA 6 0.9818 100 0.305 Contact Map
3kxuA 6 0.8848 100 0.314 Contact Map
1krqA 6 1 100 0.318 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0074 seconds.