GREMLIN Database
CSPI - Cold shock-like protein CspI
UniProt: P0A986 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13877
Length: 70 (63)
Sequences: 4231 (1686)
Seq/√Len: 212.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
32_V67_V3.5661.00
56_E65_V3.4171.00
54_G66_H2.6951.00
52_E68_V2.1901.00
8_L50_E2.1061.00
6_T52_E2.0791.00
14_P46_T2.0631.00
24_K50_E2.0491.00
38_Q68_V1.9631.00
5_M23_P1.8901.00
6_T50_E1.8131.00
23_P28_K1.6501.00
32_V45_L1.6231.00
57_N62_P1.5951.00
58_G63_A1.5731.00
46_T49_Q1.5311.00
36_A65_V1.5311.00
38_Q66_H1.5021.00
14_P42_F1.4711.00
23_P26_G1.3591.00
58_G62_P1.2841.00
30_V55_I1.2181.00
23_P53_F1.2081.00
28_K62_P1.1181.00
45_L51_V1.1141.00
14_P44_T1.1091.00
34_F43_K1.1091.00
37_I42_F1.0941.00
6_T24_K1.0941.00
8_L22_T1.0791.00
7_G21_I1.0611.00
55_I62_P1.0471.00
7_G64_A1.0231.00
21_I53_F1.0131.00
36_A56_E0.9881.00
37_I43_K0.9350.99
53_F64_A0.8920.99
12_F34_F0.8910.99
5_M25_D0.8830.99
36_A66_H0.8590.99
10_K29_D0.8540.99
58_G61_G0.8520.99
56_E63_A0.8170.99
21_I51_V0.7760.98
37_I40_N0.7680.98
15_E49_Q0.7640.98
11_W16_K0.7610.98
34_F37_I0.7380.97
10_K16_K0.7370.97
13_N31_F0.7360.97
11_W32_V0.7350.97
39_S43_K0.7280.97
22_T30_V0.7130.97
8_L24_K0.6990.96
34_F60_K0.6960.96
5_M53_F0.6650.95
34_F42_F0.6350.94
21_I64_A0.6340.93
30_V36_A0.6330.93
16_K29_D0.6280.93
20_F33_H0.6220.93
40_N68_V0.6200.93
25_D28_K0.6140.92
23_P55_I0.6020.92
5_M54_G0.5930.91
17_G29_D0.5850.90
37_I67_V0.5840.90
19_G32_V0.5830.90
22_T48_N0.5820.90
15_E63_A0.5810.90
39_S42_F0.5790.90
9_V45_L0.5740.90
54_G65_V0.5670.89
21_I32_V0.5560.88
15_E60_K0.5520.88
7_G53_F0.5460.87
12_F16_K0.5440.87
5_M28_K0.5440.87
57_N65_V0.5430.87
21_I35_S0.5420.87
5_M68_V0.5370.86
31_F49_Q0.5310.86
44_T49_Q0.5280.85
39_S44_T0.5230.85
10_K17_G0.5220.85
30_V64_A0.5200.85
15_E36_A0.5180.84
55_I65_V0.5160.84
5_M52_E0.5150.84
47_E63_A0.5070.83
37_I45_L0.5050.83
18_F33_H0.5040.83
36_A53_F0.5030.83
59_P62_P0.5000.82
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2lssA 1 1 99.8 0.143 Contact Map
1h95A 1 1 99.7 0.16 Contact Map
3i2zB 2 1 99.7 0.162 Contact Map
2mqhA 1 0.9714 99.7 0.179 Contact Map
3camA 2 0.9571 99.7 0.182 Contact Map
2ytyA 1 0.9571 99.7 0.195 Contact Map
1wfqA 1 0.9571 99.7 0.196 Contact Map
1g6pA 1 0.9286 99.7 0.198 Contact Map
1c9oA 2 0.9429 99.7 0.203 Contact Map
4qqbX 1 0.9571 99.7 0.205 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0047 seconds.