GREMLIN Database
BAME - Outer membrane protein assembly factor BamE
UniProt: P0A937 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10952
Length: 113 (99)
Sequences: 692 (487)
Seq/√Len: 48.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
93_L101_L7.4231.00
94_T103_N3.4101.00
72_T94_T3.0621.00
52_Q98_S2.8751.00
73_W95_F2.2741.00
45_K58_A2.2581.00
40_A44_S2.2391.00
48_V104_I2.0381.00
46_I101_L2.0031.00
96_N102_T1.9830.99
93_L104_I1.9740.99
66_D69_G1.8690.99
36_N61_T1.8540.99
59_L91_L1.8390.99
43_V91_L1.7830.99
19_G30_P1.7340.99
81_P84_E1.7040.98
51_T57_Y1.6710.98
37_Y53_Q1.5630.97
59_L66_D1.4790.96
91_L104_I1.4670.96
13_L16_L1.4150.95
74_F92_T1.3770.94
57_Y77_F1.3520.94
31_D82_G1.3510.93
14_L21_S1.3220.93
45_K66_D1.2710.91
29_R83_H1.2530.91
33_N57_Y1.2310.90
61_T72_T1.2250.90
32_I81_P1.1980.89
51_T54_Q1.1860.88
11_A15_M1.1770.88
54_Q57_Y1.1520.86
39_T77_F1.1340.86
38_L42_D1.1300.85
46_I93_L1.1000.84
33_N77_F1.0920.83
38_L43_V1.0800.83
33_N69_G1.0490.81
46_I104_I1.0450.81
78_R88_Q1.0410.80
46_I53_Q1.0190.79
31_D76_V1.0030.78
52_Q97_S0.9820.76
22_T29_R0.9700.75
12_V44_S0.9500.74
46_I58_A0.9300.72
28_Y62_P0.9260.72
94_T105_D0.9230.72
56_A106_N0.9090.70
39_T42_D0.9060.70
8_A18_A0.8940.69
36_N59_L0.8880.69
27_V33_N0.8820.68
45_K57_Y0.8770.68
30_P59_L0.8770.68
46_I106_N0.8740.67
78_R86_V0.8710.67
15_M18_A0.8690.67
59_L62_P0.8630.66
63_L77_F0.8540.66
38_L70_T0.8460.65
9_A12_V0.8380.64
22_T26_V0.8380.64
37_Y77_F0.8310.63
52_Q71_N0.8210.63
80_Q84_E0.8120.62
9_A15_M0.8080.61
45_K54_Q0.8080.61
16_L19_G0.7970.60
97_S100_V0.7950.60
43_V107_K0.7930.60
53_Q102_T0.7910.60
71_N96_N0.7910.60
33_N84_E0.7820.59
56_A61_T0.7780.58
39_T44_S0.7770.58
29_R86_V0.7550.56
64_M83_H0.7510.56
9_A30_P0.7370.54
29_R80_Q0.7350.54
29_R100_V0.7350.54
31_D79_Q0.7300.54
56_A90_T0.7260.53
30_P82_G0.7200.53
37_Y101_L0.7170.52
27_V63_L0.6930.50
52_Q83_H0.6900.50
58_A105_D0.6890.49
24_E43_V0.6830.49
11_A14_L0.6750.48
33_N37_Y0.6750.48
37_Y74_F0.6690.47
63_L69_G0.6690.47
90_T102_T0.6690.47
29_R36_N0.6680.47
36_N63_L0.6670.47
16_L76_V0.6650.47
7_T10_A0.6650.47
33_N79_Q0.6510.46
12_V15_M0.6470.45
69_G74_F0.6420.45
96_N103_N0.6420.45
13_L97_S0.6420.45
37_Y86_V0.6410.45
27_V30_P0.6410.45
91_L106_N0.6400.44
43_V89_Q0.6400.44
30_P88_Q0.6370.44
56_A93_L0.6350.44
63_L81_P0.6300.43
16_L105_D0.6240.43
7_T41_N0.6240.43
64_M74_F0.6230.43
21_S64_M0.6130.42
24_E97_S0.6120.42
9_A24_E0.6090.41
27_V38_L0.6080.41
21_S47_R0.6020.41
71_N102_T0.5950.40
65_S103_N0.5920.40
22_T69_G0.5910.40
65_S69_G0.5870.39
53_Q57_Y0.5730.38
9_A16_L0.5710.38
52_Q92_T0.5650.37
9_A90_T0.5640.37
31_D104_I0.5630.37
13_L17_T0.5550.36
41_N94_T0.5540.36
42_D47_R0.5490.36
27_V89_Q0.5430.35
59_L93_L0.5320.34
83_H86_V0.5290.34
45_K105_D0.5230.33
54_Q73_W0.5230.33
47_R50_M0.5220.33
74_F95_F0.5220.33
13_L70_T0.5200.33
48_V102_T0.5190.33
69_G72_T0.5180.33
17_T78_R0.5170.33
93_L103_N0.5160.33
80_Q107_K0.5110.32
27_V104_I0.5050.32
77_F104_I0.5020.31
33_N72_T0.5000.31
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2pxgA 1 0.8142 100 0.421 Contact Map
2km7A 1 0.8319 99.9 0.45 Contact Map
2yh9A 5 0.6018 99.9 0.513 Contact Map
4dm5A 1 0.6991 99.6 0.632 Contact Map
3d4eA 1 0.9204 96.6 0.847 Contact Map
3gmvX 1 0.6106 96.2 0.854 Contact Map
3n4iB 1 0.646 96.1 0.855 Contact Map
3gmxB 2 0.6372 96 0.857 Contact Map
3zbiC 1 0.2478 89.3 0.888 Contact Map
4gd5A 1 0.5929 71.9 0.908 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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