OMPX - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

OMPX - Outer membrane protein X

UniProt:	P0A917	Sequences: MKKIACLSALAAVLAFTAGTSVAATSTVTGGYAQSDAQGQMNKMGGFNLKYRYEEDNSPLGVIGSFTYTEKSRTASSGDYNKNQYYGITAGPAYRINDWASIYGVVGVGYGKFQTTEYPTYKHDTSDYGFSYGAGLQFNPMENVALDFSYEQSRIRSVDVGTWIAGVGYRF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12135
Length:	171 (166)
Sequences:	234 (164)
Seq/√Len:	12.8

ECOLI - OMPX

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
50_K	147_D	4.285	1.00
137_Q	147_D	3.959	0.99
52_R	101_S	3.578	0.99
27_T	145_A	3.218	0.98
61_G	93_A	2.988	0.96
152_Q	162_T	2.843	0.95
89_T	131_S	2.791	0.95
55_E	61_G	2.766	0.94
95_R	139_N	2.497	0.90
54_E	101_S	2.491	0.90
66_F	86_Y	2.434	0.89
50_K	137_Q	2.350	0.87
52_R	95_R	2.302	0.86
69_T	162_T	2.248	0.85
48_N	65_S	2.240	0.85
54_E	95_R	2.239	0.85
50_K	153_S	2.179	0.83
54_E	139_N	2.133	0.82
137_Q	145_A	2.037	0.78
140_P	167_V	2.009	0.77
52_R	93_A	1.997	0.77
24_A	62_V	1.946	0.75
95_R	101_S	1.907	0.73
3_K	6_C	1.900	0.73
52_R	139_N	1.868	0.72
35_S	69_T	1.864	0.72
71_K	162_T	1.799	0.69
137_Q	166_G	1.758	0.67
67_T	85_Y	1.727	0.66
37_A	40_Q	1.690	0.64
147_D	153_S	1.645	0.62
24_A	45_G	1.643	0.62
64_G	141_M	1.626	0.61
9_A	12_A	1.625	0.61
27_T	102_I	1.578	0.58
85_Y	151_E	1.570	0.58
149_S	164_I	1.569	0.58
34_Q	45_G	1.513	0.55
36_D	138_F	1.513	0.55
12_A	66_F	1.465	0.53
149_S	154_R	1.410	0.50
34_Q	44_M	1.380	0.48
27_T	94_Y	1.363	0.47
89_T	104_G	1.352	0.47
109_G	153_S	1.342	0.46
141_M	153_S	1.337	0.46
50_K	155_I	1.292	0.44
129_G	157_S	1.273	0.43
68_Y	86_Y	1.267	0.42
90_A	144_V	1.254	0.42
60_L	164_I	1.251	0.42
18_A	28_V	1.231	0.41
27_T	67_T	1.231	0.41
148_F	165_A	1.229	0.40
91_G	107_G	1.226	0.40
30_G	126_S	1.211	0.40
109_G	131_S	1.194	0.39
101_S	139_N	1.183	0.38
62_V	156_R	1.182	0.38
49_L	68_Y	1.181	0.38
149_S	162_T	1.169	0.37
55_E	93_A	1.159	0.37
133_G	169_Y	1.158	0.37
35_S	162_T	1.127	0.35
44_M	71_K	1.115	0.35
68_Y	132_Y	1.110	0.35
60_L	96_I	1.079	0.33
98_D	104_G	1.058	0.32
37_A	86_Y	1.055	0.32
154_R	159_D	1.052	0.32
26_S	51_Y	1.047	0.32
4_I	8_S	1.034	0.31
55_E	58_S	1.023	0.31
69_T	161_G	1.010	0.30
68_Y	104_G	1.009	0.30
7_L	12_A	1.004	0.30
111_G	166_G	0.999	0.30
9_A	142_E	0.991	0.29
154_R	158_V	0.990	0.29
30_G	100_A	0.984	0.29
33_A	162_T	0.963	0.28
5_A	146_L	0.953	0.28
7_L	10_L	0.952	0.28
6_C	9_A	0.950	0.28
61_G	111_G	0.949	0.28
64_G	132_Y	0.940	0.27
49_L	54_E	0.935	0.27
63_I	75_A	0.930	0.27
96_I	143_N	0.929	0.27
56_D	170_R	0.911	0.26
64_G	99_W	0.909	0.26
69_T	160_V	0.907	0.26
89_T	163_W	0.905	0.26
131_S	164_I	0.876	0.25
71_K	152_Q	0.870	0.24
52_R	112_K	0.863	0.24
13_V	16_F	0.860	0.24
142_E	149_S	0.859	0.24
108_V	128_Y	0.848	0.24
35_S	160_V	0.846	0.23
37_A	160_V	0.842	0.23
60_L	93_A	0.840	0.23
152_Q	163_W	0.837	0.23
42_N	83_N	0.832	0.23
149_S	155_I	0.825	0.23
15_A	67_T	0.824	0.23
62_V	67_T	0.816	0.22
77_S	123_H	0.812	0.22
13_V	109_G	0.810	0.22
61_G	80_Y	0.809	0.22
38_Q	153_S	0.801	0.22
130_F	153_S	0.801	0.22
14_L	138_F	0.796	0.22
152_Q	161_G	0.792	0.22
133_G	151_E	0.787	0.21
77_S	136_L	0.784	0.21
43_K	138_F	0.784	0.21
5_A	153_S	0.784	0.21
26_S	35_S	0.775	0.21
40_Q	70_E	0.774	0.21
133_G	149_S	0.766	0.21
97_N	139_N	0.764	0.21
29_T	87_G	0.759	0.20
63_I	137_Q	0.758	0.20
147_D	166_G	0.750	0.20
155_I	160_V	0.749	0.20
38_Q	152_Q	0.744	0.20
29_T	137_Q	0.743	0.20
120_T	165_A	0.738	0.20
28_V	134_A	0.736	0.20
98_D	121_Y	0.736	0.20
50_K	145_A	0.735	0.20
8_S	64_G	0.732	0.19
69_T	132_Y	0.728	0.19
63_I	105_V	0.727	0.19
64_G	131_S	0.727	0.19
16_F	100_A	0.726	0.19
88_I	146_L	0.726	0.19
92_P	169_Y	0.726	0.19
27_T	139_N	0.726	0.19
59_P	93_A	0.725	0.19
132_Y	162_T	0.717	0.19
33_A	85_Y	0.715	0.19
24_A	63_I	0.715	0.19
8_S	11_A	0.714	0.19
100_A	113_F	0.708	0.19
104_G	142_E	0.707	0.19
113_F	128_Y	0.704	0.19
103_Y	150_Y	0.701	0.19
100_A	165_A	0.700	0.18
6_C	16_F	0.699	0.18
106_V	167_V	0.690	0.18
132_Y	152_Q	0.689	0.18
47_F	83_N	0.687	0.18
33_A	133_G	0.686	0.18
26_S	102_I	0.681	0.18
23_A	56_D	0.680	0.18
71_K	161_G	0.680	0.18
45_G	124_D	0.678	0.18
8_S	63_I	0.673	0.18
7_L	15_A	0.669	0.18
151_E	168_G	0.667	0.17
92_P	101_S	0.667	0.17
50_K	111_G	0.665	0.17
58_S	124_D	0.657	0.17
104_G	141_M	0.657	0.17
5_A	13_V	0.656	0.17
19_G	22_V	0.655	0.17
87_G	155_I	0.654	0.17
127_D	155_I	0.644	0.17
9_A	13_V	0.642	0.17
22_V	67_T	0.642	0.17
46_G	135_G	0.640	0.17
98_D	145_A	0.639	0.17
92_P	95_R	0.638	0.17
29_T	147_D	0.635	0.17
79_D	116_T	0.633	0.16
140_P	154_R	0.632	0.16
147_D	154_R	0.629	0.16
111_G	131_S	0.628	0.16
86_Y	112_K	0.627	0.16
125_T	165_A	0.626	0.16
88_I	130_F	0.621	0.16
96_I	106_V	0.619	0.16
5_A	100_A	0.618	0.16
161_G	164_I	0.615	0.16
115_T	126_S	0.609	0.16
93_A	150_Y	0.609	0.16
82_K	114_Q	0.608	0.16
11_A	19_G	0.605	0.16
44_M	61_G	0.602	0.16
49_L	117_E	0.601	0.16
49_L	108_V	0.601	0.16
9_A	80_Y	0.599	0.16
14_L	27_T	0.599	0.16
81_N	148_F	0.595	0.15
102_I	157_S	0.594	0.15
7_L	11_A	0.593	0.15
149_S	158_V	0.590	0.15
48_N	105_V	0.588	0.15
147_D	155_I	0.585	0.15
83_N	87_G	0.583	0.15
115_T	120_T	0.582	0.15
49_L	100_A	0.582	0.15
28_V	104_G	0.580	0.15
10_L	60_L	0.579	0.15
68_Y	166_G	0.574	0.15
5_A	11_A	0.574	0.15
4_I	15_A	0.574	0.15
148_F	162_T	0.570	0.15
5_A	25_T	0.569	0.15
23_A	139_N	0.568	0.15
109_G	147_D	0.566	0.15
117_E	123_H	0.566	0.15
71_K	163_W	0.565	0.15
8_S	49_L	0.565	0.15
26_S	53_Y	0.560	0.15
6_C	109_G	0.560	0.15
14_L	18_A	0.557	0.14
132_Y	140_P	0.557	0.14
105_V	164_I	0.557	0.14
35_S	47_F	0.553	0.14
37_A	125_T	0.545	0.14
66_F	130_F	0.544	0.14
60_L	124_D	0.541	0.14
14_L	30_G	0.539	0.14
16_F	124_D	0.539	0.14
79_D	158_V	0.539	0.14
27_T	54_E	0.530	0.14
141_M	144_V	0.529	0.14
34_Q	169_Y	0.526	0.14
9_A	15_A	0.526	0.14
72_S	130_F	0.525	0.14
46_G	168_G	0.518	0.13
135_G	168_G	0.518	0.13
71_K	164_I	0.517	0.13
109_G	115_T	0.516	0.13
4_I	10_L	0.516	0.13
132_Y	169_Y	0.511	0.13
140_P	143_N	0.511	0.13
78_G	153_S	0.510	0.13
50_K	104_G	0.509	0.13
150_Y	168_G	0.505	0.13
7_L	129_G	0.505	0.13
62_V	99_W	0.504	0.13
74_T	86_Y	0.504	0.13
15_A	19_G	0.503	0.13
26_S	52_R	0.500	0.13
58_S	156_R	0.500	0.13

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1ormA	1	0.8596	99.9	0.578	Contact Map
3qraA	1	0.8655	99.9	0.616	Contact Map
3nb3A	2	0.7719	99.7	0.7	Contact Map
2k0lA	1	0.9532	99.6	0.74	Contact Map
1qjpA	1	0.7836	99.5	0.751	Contact Map
2jmmA	1	0.8129	99.5	0.754	Contact Map
1p4tA	2	0.848	99.2	0.786	Contact Map
2lhfA	1	0.8246	99.2	0.79	Contact Map
4rlcA	1	0.7602	99.2	0.79	Contact Map
2x27X	1	0.9006	99.1	0.793	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0077 seconds.