GREMLIN Database
SLYB - Outer membrane lipoprotein SlyB
UniProt: P0A905 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13409
Length: 155 (140)
Sequences: 788 (559)
Seq/√Len: 47.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
49_R113_E4.5151.00
76_N84_R3.6951.00
63_G99_G3.1231.00
74_L78_V2.9261.00
53_I111_G2.8001.00
68_A96_G2.7221.00
102_V106_M2.6951.00
72_G92_A2.6331.00
86_L90_A2.3411.00
68_A72_G2.3231.00
76_N88_T2.3201.00
60_N103_Q2.2471.00
101_G104_S2.2231.00
84_R88_T2.1981.00
43_G116_I2.1981.00
39_N42_Y2.1871.00
78_V87_A2.1791.00
45_I48_V2.1401.00
46_V123_T1.9940.99
119_D140_R1.9440.99
98_A102_V1.9160.99
25_S28_V1.9080.99
46_V117_R1.8710.99
136_S139_Q1.8570.99
109_T129_K1.8360.99
50_P112_V1.8340.99
73_F85_S1.7940.99
93_V97_V1.7380.98
69_V89_A1.7380.98
61_V103_Q1.6790.98
62_I66_G1.6720.98
98_A101_G1.6170.97
56_G59_S1.5350.96
79_G83_G1.3930.94
90_A94_A1.3610.93
45_I135_F1.3590.93
10_M14_S1.3560.93
69_V73_F1.3540.93
103_Q107_N1.3450.93
50_P110_Q1.3310.92
104_S108_K1.3190.92
48_V137_P1.2900.91
89_A108_K1.2820.91
52_Q108_K1.2690.90
99_G103_Q1.2630.90
92_A96_G1.2600.90
67_G99_G1.2270.89
43_G141_V1.1810.87
80_G86_L1.1480.85
15_L18_C1.1080.83
125_M144_A1.1020.83
63_G103_Q1.0990.83
55_G108_K1.0910.82
72_G76_N1.0760.81
114_L139_Q1.0660.81
16_V92_A1.0630.80
66_G84_R1.0600.80
54_Q104_S1.0560.80
147_G150_V1.0420.79
65_I69_V1.0170.77
76_N85_S1.0130.77
91_G95_G0.9940.76
68_A103_Q0.9900.75
70_L116_I0.9800.75
45_I118_K0.9760.74
41_S118_K0.9680.74
50_P72_G0.9640.74
71_G95_G0.9580.73
59_S100_Q0.9570.73
63_G67_G0.9530.73
27_D132_N0.9380.71
37_V41_S0.9380.71
45_I114_L0.9350.71
118_K148_S0.9350.71
95_G99_G0.9340.71
74_L97_V0.9340.71
42_Y142_V0.9310.71
111_G128_Q0.9200.70
115_E142_V0.9140.69
94_A143_L0.9130.69
43_G108_K0.9120.69
56_G107_N0.9040.69
48_V112_V0.8840.67
67_G95_G0.8810.67
64_A69_V0.8670.65
85_S89_A0.8540.64
73_F89_A0.8530.64
59_S103_Q0.8470.64
125_M143_L0.8450.63
39_N119_D0.8430.63
55_G107_N0.8410.63
63_G95_G0.8380.63
46_V137_P0.8370.63
114_L128_Q0.8370.63
113_E127_V0.8110.60
64_A100_Q0.8090.60
30_T55_G0.8050.60
94_A97_V0.8040.59
37_V145_S0.7980.59
89_A92_A0.7910.58
100_Q104_S0.7850.58
77_T88_T0.7800.57
66_G96_G0.7790.57
7_V11_V0.7760.57
48_V135_F0.7750.57
55_G59_S0.7690.56
31_A55_G0.7680.56
42_Y119_D0.7670.56
47_N113_E0.7600.55
74_L77_T0.7310.52
67_G71_G0.7240.52
126_V150_V0.7120.50
54_Q68_A0.7110.50
118_K124_I0.7090.50
128_Q133_T0.7080.50
51_V111_G0.7050.50
76_N79_G0.7000.49
65_I105_A0.7000.49
15_L21_N0.6980.49
64_A137_P0.6970.49
14_S45_I0.6920.48
93_V110_Q0.6910.48
146_N149_Q0.6860.48
6_L14_S0.6850.48
77_T94_A0.6790.47
12_G15_L0.6740.47
44_T68_A0.6680.46
44_T101_G0.6660.46
73_F90_A0.6580.45
10_M19_V0.6550.45
37_V65_I0.6550.45
11_V17_G0.6530.45
97_V100_Q0.6530.45
116_I124_I0.6510.44
21_N107_N0.6500.44
43_G95_G0.6500.44
145_S149_Q0.6490.44
102_V105_A0.6490.44
55_G127_V0.6480.44
21_N24_L0.6460.44
122_N126_V0.6420.43
44_T121_G0.6410.43
59_S107_N0.6380.43
37_V124_I0.6370.43
113_E142_V0.6300.42
29_Y128_Q0.6300.42
14_S17_G0.6300.42
52_Q110_Q0.6280.42
44_T126_V0.6280.42
124_I150_V0.6210.41
135_F139_Q0.6200.41
35_K129_K0.6130.41
54_Q108_K0.6090.40
77_T112_V0.6080.40
39_N145_S0.6060.40
46_V142_V0.6040.40
10_M32_S0.5930.39
26_G35_K0.5920.39
44_T128_Q0.5920.39
82_T88_T0.5750.37
112_V135_F0.5730.37
15_L20_N0.5720.37
93_V102_V0.5690.37
101_G105_A0.5680.36
139_Q144_A0.5650.36
66_G111_G0.5640.36
24_L27_D0.5640.36
41_S122_N0.5640.36
50_P130_Q0.5640.36
9_S14_S0.5590.36
98_A103_Q0.5570.35
29_Y111_G0.5560.35
13_L64_A0.5540.35
78_V150_V0.5520.35
77_T82_T0.5520.35
122_N143_L0.5500.35
33_E86_L0.5500.35
46_V98_A0.5460.34
25_S51_V0.5450.34
69_V92_A0.5410.34
49_R144_A0.5400.34
8_V14_S0.5400.34
70_L74_L0.5390.34
11_V14_S0.5390.34
74_L84_R0.5390.34
28_V68_A0.5380.34
45_I52_Q0.5380.34
51_V69_V0.5360.34
44_T138_G0.5320.33
72_G88_T0.5310.33
24_L129_K0.5290.33
87_A129_K0.5280.33
82_T147_G0.5270.33
51_V109_T0.5260.33
62_I80_G0.5250.33
26_G40_V0.5250.33
17_G127_V0.5250.33
35_K114_L0.5220.32
38_Q42_Y0.5200.32
79_G82_T0.5180.32
63_G102_V0.5150.32
70_L84_R0.5130.32
34_A40_V0.5120.31
55_G111_G0.5100.31
119_D135_F0.5020.31
50_P111_G0.5020.31
17_G20_N0.5010.30
15_L40_V0.5000.30
60_N101_G0.5000.30
13_L74_L0.5000.30
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3zbiC 1 0.1742 73 0.907 Contact Map
3ldtA 2 0.3097 47.9 0.921 Contact Map
2fl7A 1 0.2839 29.5 0.93 Contact Map
2l66A 2 0.2903 24.8 0.932 Contact Map
1gutA 5 0.3871 18 0.937 Contact Map
4qflA 1 0.5677 17.7 0.937 Contact Map
4jjnK 1 0.3032 17.3 0.937 Contact Map
1fr3A 5 0.3935 16.9 0.937 Contact Map
4r9fA 1 0.4839 14.4 0.939 Contact Map
1yr2A 1 0.6968 12.2 0.941 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0064 seconds.