GREMLIN Database
BAMC - Outer membrane protein assembly factor BamC
UniProt: P0A903 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10658
Length: 344 (327)
Sequences: 710 (535)
Seq/√Len: 29.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
307_V314_S4.9731.00
268_D277_A4.5191.00
108_V174_V3.9461.00
121_V134_R3.8711.00
131_I134_R3.7471.00
270_T273_Q3.6311.00
264_M280_Y3.1861.00
256_P276_M3.1611.00
244_V251_V3.1261.00
248_F268_D3.1151.00
268_D271_R3.0041.00
52_A56_M2.7191.00
124_L141_L2.6441.00
132_T144_D2.6161.00
166_K171_Q2.6161.00
198_S261_K2.6011.00
320_D324_H2.4990.99
15_G24_A2.4920.99
186_K190_D2.3490.99
163_I172_Q2.3200.99
23_A182_E2.3020.99
130_T144_D2.1900.98
11_A24_A2.1550.98
277_A304_K2.0990.98
157_Y188_V2.0920.98
266_V278_V2.0560.97
39_E43_E2.0160.97
161_Y174_V1.9870.97
278_V305_L1.9850.97
248_F274_G1.9730.97
251_V316_L1.9550.96
131_I141_L1.9410.96
176_V205_I1.9370.96
106_L206_S1.8990.96
114_N165_V1.8960.96
114_N118_P1.8900.96
133_Q142_T1.8790.96
308_G315_S1.8780.96
123_V204_V1.8600.95
35_V39_E1.8210.95
67_I120_V1.7890.94
268_D272_S1.7540.94
95_A108_V1.7520.94
24_A65_Y1.7240.93
117_W141_L1.7000.92
254_R263_G1.6800.92
275_N305_L1.6620.92
118_P218_N1.6590.91
166_K173_A1.6560.91
124_L143_T1.6480.91
51_H54_A1.6400.91
20_L24_A1.6220.91
218_N307_V1.6190.90
104_A198_S1.6090.90
52_A270_T1.5930.90
289_Q293_A1.5690.89
119_Q209_L1.5640.89
243_V315_S1.5620.89
98_Q107_L1.5600.89
200_E204_V1.5580.89
108_V116_L1.5460.88
260_E266_V1.5340.88
337_V340_A1.5200.87
104_A178_L1.5110.87
157_Y198_S1.5090.87
73_S126_A1.4800.86
54_A175_T1.4740.86
235_D239_L1.4660.85
18_L21_L1.4540.85
65_Y96_R1.4540.85
289_Q292_G1.4340.84
138_G176_V1.4240.84
40_A43_E1.4230.84
246_G251_V1.3970.82
159_G198_S1.3960.82
205_I209_L1.3960.82
164_S175_T1.3950.82
80_L84_P1.3840.82
326_L330_Q1.3800.82
17_S316_L1.3740.81
116_L209_L1.3690.81
77_G85_P1.3680.81
248_F271_R1.3660.81
43_E129_Y1.3650.81
100_T103_T1.3640.81
18_L120_V1.3550.80
13_V19_V1.3540.80
252_W271_R1.3490.80
253_Q257_A1.3440.80
74_G81_D1.3370.80
318_F334_L1.3310.79
22_L25_C1.3310.79
142_T287_D1.3270.79
310_L313_R1.3170.79
243_V247_P1.3120.78
104_A199_T1.3100.78
262_V339_Q1.3080.78
102_D207_A1.3080.78
142_T160_R1.3040.78
105_S250_V1.2940.77
64_D281_K1.2920.77
171_Q268_D1.2880.77
151_L183_Q1.2820.77
201_M306_Q1.2720.76
264_M318_F1.2660.76
106_L202_M1.2600.75
11_A22_L1.2600.75
298_L320_D1.2580.75
18_L222_N1.2480.75
82_I85_P1.2450.74
95_A206_S1.2440.74
124_L129_Y1.2440.74
128_N210_D1.2420.74
162_Q175_T1.2230.73
120_V163_I1.2210.73
180_N191_A1.2170.73
264_M283_L1.2040.72
127_K311_D1.2020.72
268_D276_M1.1990.72
145_W240_P1.1930.71
193_S198_S1.1930.71
181_L190_D1.1890.71
264_M337_V1.1830.71
174_V336_A1.1730.70
107_L173_A1.1710.70
131_I332_D1.1650.69
12_K17_S1.1630.69
123_V286_S1.1470.68
306_Q319_I1.1460.68
161_Y176_V1.1450.68
101_G147_Q1.1390.68
258_A266_V1.1380.67
159_G197_Y1.1380.67
206_S210_D1.1260.67
73_S320_D1.1210.66
124_L161_Y1.1120.66
105_S173_A1.1080.65
124_L155_E1.1050.65
27_S45_A1.1040.65
147_Q201_M1.0970.65
70_T163_I1.0930.64
218_N222_N1.0920.64
306_Q317_Q1.0820.63
141_L161_Y1.0800.63
99_F212_S1.0750.63
97_T238_G1.0740.63
96_R209_L1.0730.63
65_Y284_S1.0680.62
252_W268_D1.0660.62
112_R221_Q1.0620.62
274_G337_V1.0600.62
166_K169_G1.0580.62
54_A162_Q1.0560.62
19_V313_R1.0550.62
309_D313_R1.0530.61
264_M334_L1.0490.61
65_Y152_D1.0480.61
207_A210_D1.0360.60
99_F199_T1.0360.60
105_S166_K1.0280.59
35_V65_Y1.0240.59
147_Q156_Q1.0200.59
280_Y283_L1.0050.58
284_S292_G0.9810.56
220_A224_A0.9780.56
156_Q176_V0.9770.56
99_F178_L0.9750.55
65_Y254_R0.9740.55
306_Q323_G0.9720.55
278_V317_Q0.9710.55
20_L79_A0.9690.55
157_Y178_L0.9690.55
269_S276_M0.9660.55
93_S311_D0.9650.55
78_K83_R0.9620.54
285_D342_F0.9600.54
135_D273_Q0.9540.54
266_V319_I0.9540.54
70_T314_S0.9500.53
141_L157_Y0.9490.53
36_S63_G0.9470.53
136_D199_T0.9420.53
118_P305_L0.9370.52
164_S276_M0.9350.52
173_A273_Q0.9330.52
270_T277_A0.9290.52
175_T244_V0.9280.52
123_V208_G0.9250.51
80_L83_R0.9230.51
266_V323_G0.9200.51
88_P303_Y0.9180.51
106_L305_L0.9180.51
64_D304_K0.9120.50
280_Y303_Y0.9090.50
145_W158_R0.9090.50
193_S212_S0.9080.50
328_Q340_A0.9060.50
53_P56_M0.8990.49
162_Q177_K0.8930.49
160_R291_L0.8930.49
337_V341_A0.8880.49
41_Y274_G0.8860.48
75_A278_V0.8820.48
223_R338_F0.8820.48
116_L192_A0.8790.48
160_R269_S0.8780.48
11_A20_L0.8740.47
179_L260_E0.8710.47
123_V164_S0.8650.47
43_E295_D0.8640.47
117_W143_T0.8630.47
279_T337_V0.8600.46
55_G206_S0.8530.46
265_K283_L0.8520.46
160_R201_M0.8490.45
54_A194_M0.8470.45
216_A251_V0.8430.45
27_S329_S0.8410.45
106_L205_I0.8390.45
262_V305_L0.8340.44
42_L279_T0.8330.44
17_S232_S0.8320.44
310_L315_S0.8300.44
94_G288_W0.8250.44
320_D335_V0.8240.44
37_G165_V0.8240.44
335_V338_F0.8240.44
248_F272_S0.8240.44
246_G253_Q0.8220.43
99_F269_S0.8180.43
104_A108_V0.8160.43
14_A21_L0.8150.43
267_T302_D0.8130.43
238_G315_S0.8040.42
200_E261_K0.8020.42
181_L189_A0.8000.42
137_A305_L0.7990.42
71_N296_P0.7950.41
205_I227_T0.7950.41
48_A293_A0.7850.41
67_I326_L0.7840.40
44_A67_I0.7830.40
255_L316_L0.7800.40
238_G312_N0.7800.40
244_V316_L0.7780.40
97_T146_V0.7760.40
43_E197_Y0.7730.40
67_I263_G0.7730.40
233_A238_G0.7710.39
94_G263_G0.7710.39
232_S335_V0.7690.39
118_P216_A0.7690.39
248_F276_M0.7680.39
20_L141_L0.7670.39
115_T158_R0.7660.39
182_E288_W0.7650.39
148_W264_M0.7650.39
17_S184_A0.7630.39
54_A154_D0.7610.39
212_S334_L0.7610.39
116_L271_R0.7590.39
233_A236_D0.7570.38
314_S325_T0.7510.38
176_V334_L0.7500.38
148_W334_L0.7490.38
14_A19_V0.7490.38
94_G137_A0.7490.38
80_L135_D0.7490.38
237_T310_L0.7480.38
289_Q294_S0.7440.37
91_L315_S0.7430.37
19_V77_G0.7430.37
124_L174_V0.7430.37
135_D138_G0.7410.37
320_D325_T0.7370.37
102_D209_L0.7350.37
21_L312_N0.7340.37
94_G110_N0.7330.37
58_L314_S0.7320.37
56_M159_G0.7310.36
145_W303_Y0.7290.36
188_V335_V0.7280.36
80_L94_G0.7280.36
156_Q305_L0.7260.36
21_L26_S0.7260.36
290_E331_N0.7250.36
105_S198_S0.7230.36
255_L317_Q0.7220.36
23_A101_G0.7220.36
194_M260_E0.7200.36
21_L114_N0.7190.36
80_L85_P0.7160.35
150_R192_A0.7140.35
159_G178_L0.7120.35
19_V217_A0.7110.35
145_W254_R0.7110.35
204_V290_E0.7090.35
103_T175_T0.7080.35
286_S289_Q0.7080.35
41_Y106_L0.7060.35
104_A123_V0.7060.35
260_E282_P0.7060.35
116_L245_R0.7050.35
59_P65_Y0.7040.35
77_G82_I0.7030.34
18_L235_D0.7030.34
188_V198_S0.7010.34
11_A16_V0.7000.34
252_W270_T0.7000.34
96_R182_E0.7000.34
51_H55_G0.6990.34
48_A276_M0.6970.34
233_A243_V0.6970.34
102_D340_A0.6950.34
19_V38_D0.6930.34
129_Y159_G0.6910.34
267_T279_T0.6900.34
76_V80_L0.6890.33
55_G338_F0.6880.33
150_R205_I0.6870.33
316_L331_N0.6870.33
146_V176_V0.6850.33
106_L207_A0.6850.33
141_L341_A0.6820.33
105_S112_R0.6820.33
87_Q309_D0.6810.33
104_A143_T0.6780.33
135_D315_S0.6770.33
218_N225_S0.6730.32
71_N222_N0.6690.32
245_R295_D0.6690.32
136_D335_V0.6690.32
247_P327_T0.6690.32
105_S139_Q0.6640.32
320_D326_L0.6630.32
122_S290_E0.6630.32
82_I91_L0.6630.32
311_D336_A0.6610.32
75_A81_D0.6590.31
252_W269_S0.6580.31
275_N322_K0.6530.31
19_V76_V0.6520.31
117_W160_R0.6510.31
43_E155_E0.6480.31
122_S163_I0.6460.31
271_R278_V0.6450.30
44_A340_A0.6440.30
28_D189_A0.6430.30
147_Q276_M0.6430.30
146_V181_L0.6420.30
118_P174_V0.6420.30
115_T119_Q0.6400.30
236_D329_S0.6400.30
22_L137_A0.6400.30
25_C53_P0.6390.30
132_T187_P0.6370.30
16_V242_L0.6340.30
35_V61_T0.6340.30
254_R259_L0.6330.30
237_T315_S0.6320.30
160_R274_G0.6320.30
74_G80_L0.6300.29
92_V206_S0.6300.29
208_G249_N0.6280.29
89_L145_W0.6260.29
15_G61_T0.6240.29
160_R271_R0.6220.29
126_A211_K0.6170.29
119_Q340_A0.6160.29
180_N261_K0.6150.28
128_N258_A0.6150.28
309_D312_N0.6150.28
251_V270_T0.6140.28
68_P101_G0.6130.28
16_V220_A0.6120.28
21_L309_D0.6110.28
18_L116_L0.6090.28
19_V185_G0.6090.28
28_D331_N0.6080.28
23_A304_K0.6070.28
101_G162_Q0.6070.28
97_T159_G0.6070.28
106_L199_T0.6060.28
209_L303_Y0.6060.28
42_L328_Q0.6060.28
28_D288_W0.6060.28
194_M197_Y0.6050.28
335_V339_Q0.6030.28
249_N271_R0.6020.28
50_L157_Y0.6020.28
36_S265_K0.6000.28
94_G248_F0.6000.28
275_N304_K0.5980.27
77_G80_L0.5960.27
218_N314_S0.5940.27
81_D84_P0.5920.27
303_Y314_S0.5920.27
145_W238_G0.5920.27
138_G304_K0.5910.27
51_H140_T0.5900.27
69_V74_G0.5890.27
52_A58_L0.5890.27
84_P91_L0.5840.27
138_G214_T0.5840.27
118_P213_A0.5830.26
106_L266_V0.5820.26
108_V124_L0.5820.26
100_T168_Q0.5800.26
97_T121_V0.5800.26
121_V125_Q0.5800.26
318_F331_N0.5780.26
177_K273_Q0.5760.26
232_S240_P0.5760.26
178_L188_V0.5760.26
26_S236_D0.5760.26
68_P145_W0.5740.26
199_T330_Q0.5730.26
196_R263_G0.5720.26
53_P139_Q0.5720.26
268_D274_G0.5710.26
216_A221_Q0.5700.26
60_V293_A0.5670.26
146_V157_Y0.5660.25
244_V342_F0.5640.25
123_V188_V0.5640.25
21_L222_N0.5600.25
105_S210_D0.5580.25
147_Q188_V0.5570.25
252_W314_S0.5560.25
255_L318_F0.5560.25
169_G226_T0.5560.25
126_A273_Q0.5560.25
252_W287_D0.5560.25
116_L163_I0.5510.25
94_G291_L0.5500.25
67_I305_L0.5500.25
143_T270_T0.5450.24
129_Y144_D0.5450.24
304_K326_L0.5440.24
66_A218_N0.5440.24
338_F342_F0.5430.24
75_A78_K0.5430.24
87_Q245_R0.5430.24
104_A139_Q0.5420.24
266_V286_S0.5420.24
40_A314_S0.5410.24
269_S334_L0.5390.24
293_A313_R0.5390.24
130_T293_A0.5390.24
272_S277_A0.5390.24
88_P145_W0.5370.24
50_L108_V0.5360.24
72_G295_D0.5360.24
219_A222_N0.5350.24
59_P180_N0.5340.24
100_T108_V0.5330.24
22_L299_A0.5330.24
74_G322_K0.5310.23
61_T296_P0.5310.23
265_K334_L0.5300.23
42_L57_I0.5290.23
201_M269_S0.5270.23
66_A220_A0.5270.23
129_Y255_L0.5260.23
248_F252_W0.5250.23
62_S317_Q0.5240.23
71_N219_A0.5230.23
209_L342_F0.5230.23
164_S256_P0.5220.23
221_Q272_S0.5200.23
120_V205_I0.5190.23
68_P272_S0.5180.23
97_T306_Q0.5180.23
241_M317_Q0.5170.23
177_K194_M0.5160.23
79_A232_S0.5160.23
14_A22_L0.5100.22
12_K24_A0.5100.22
110_N322_K0.5090.22
245_R308_G0.5090.22
101_G199_T0.5090.22
75_A242_L0.5080.22
134_R263_G0.5060.22
134_R342_F0.5050.22
233_A241_M0.5050.22
304_K316_L0.5040.22
256_P259_L0.5030.22
147_Q157_Y0.5000.22
187_P190_D0.5000.22
192_A198_S0.5000.22
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3tgoC 2 0.5407 100 0.154 Contact Map
2yh5A 1 0.3459 100 0.65 Contact Map
2yh6A 2 0.3169 99.6 0.807 Contact Map
3zbiC 1 0.0785 62.9 0.954 Contact Map
4av2M 1 0.218 36 0.961 Contact Map
4yo7A 1 0.5262 24 0.964 Contact Map
4yahX 1 0.5901 20.4 0.965 Contact Map
3vxbA 1 0.5436 20 0.966 Contact Map
4ys6A 1 0.5262 20 0.966 Contact Map
3un6A 1 0.7151 15.1 0.967 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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