GREMLIN Database
YJGA - UPF0307 protein YjgA
UniProt: P0A8X0 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11410
Length: 183 (163)
Sequences: 748 (500)
Seq/√Len: 39.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
30_S34_R6.2641.00
45_E105_K4.0601.00
76_E79_R3.7491.00
60_D92_R3.6011.00
133_I152_I2.7731.00
173_Q176_R2.5261.00
31_E35_D2.3311.00
165_P169_R2.3101.00
46_I54_L2.2861.00
98_R102_D2.2390.99
43_G86_G2.2370.99
136_V143_A2.2000.99
69_L72_R2.1820.99
38_E98_R2.1340.99
118_L175_L2.0340.99
73_I77_G1.9830.99
116_H169_R1.9160.98
44_A48_D1.8830.98
168_A173_Q1.8830.98
166_K170_Q1.7930.98
125_L152_I1.7850.97
130_D156_K1.7270.97
40_K83_Q1.7120.97
71_Q81_Q1.6630.96
128_Q132_A1.5760.95
121_L136_V1.5510.94
136_V175_L1.5400.94
135_E139_L1.5270.94
92_R96_P1.5200.94
37_E41_R1.5030.93
123_D168_A1.4780.93
87_K91_Q1.4480.92
79_R83_Q1.4390.92
147_Q174_Y1.4350.91
47_V70_A1.4270.91
47_V67_I1.4260.91
40_K89_L1.4050.91
119_E122_R1.3820.90
158_E165_P1.3730.90
78_R82_L1.3490.89
122_R172_F1.3360.88
134_A145_R1.3350.88
43_G85_I1.3250.88
54_L71_Q1.3130.87
129_G132_A1.2950.87
121_L124_R1.2860.86
115_F172_F1.2840.86
143_A178_L1.2490.85
51_K71_Q1.2470.84
137_L143_A1.2440.84
36_A40_K1.2340.84
124_R135_E1.2330.84
27_V31_E1.2270.83
112_V115_F1.2260.83
40_K79_R1.2240.83
43_G63_L1.2210.83
31_E34_R1.2170.83
118_L179_A1.2140.83
136_V178_L1.2120.83
83_Q86_G1.2090.83
119_E172_F1.2010.82
57_I100_A1.1960.82
57_I104_L1.1820.81
115_F168_A1.1810.81
36_A39_L1.1570.80
63_L85_I1.1390.79
61_A64_R1.1370.78
129_G145_R1.1200.77
40_K86_G1.1160.77
158_E164_P1.1120.77
172_F176_R1.1120.77
156_K160_E1.0980.76
50_G53_A1.0940.76
168_A176_R1.0740.74
25_I35_D1.0700.74
125_L133_I1.0590.73
127_D159_K1.0590.73
132_A135_E1.0540.73
132_A136_V1.0360.72
54_L81_Q1.0330.71
83_Q89_L1.0330.71
70_A81_Q1.0240.71
169_R172_F1.0130.70
53_A150_T1.0120.70
153_R157_K1.0080.69
137_L145_R0.9850.68
41_R44_A0.9770.67
49_L101_L0.9750.67
111_Q114_L0.9700.66
55_D64_R0.9570.65
63_L97_I0.9490.65
83_Q90_R0.9420.64
65_A69_L0.9350.64
62_D84_L0.9250.63
58_P100_A0.9230.63
32_I36_A0.9230.63
84_L92_R0.9180.62
150_T171_I0.9160.62
60_D81_Q0.9150.62
115_F118_L0.9050.61
154_N167_S0.9050.61
47_V82_L0.9030.61
140_W179_A0.8920.60
36_A89_L0.8810.59
135_E138_N0.8730.58
136_V179_A0.8720.58
48_D70_A0.8670.58
174_Y178_L0.8630.57
77_G85_I0.8610.57
32_I89_L0.8600.57
143_A174_Y0.8590.57
146_Q153_R0.8480.56
24_I30_S0.8460.56
88_M92_R0.8450.56
162_N165_P0.8360.55
24_I27_V0.8340.55
167_S170_Q0.8310.54
24_I109_N0.8290.54
121_L175_L0.8220.54
63_L86_G0.8180.53
19_D23_E0.8130.53
59_L64_R0.8130.53
64_R68_E0.8120.53
77_G81_Q0.8110.53
32_I40_K0.8100.53
53_A104_L0.8080.52
59_L88_M0.8050.52
43_G83_Q0.8040.52
123_D159_K0.7880.51
29_K36_A0.7860.50
67_I81_Q0.7810.50
28_S86_G0.7810.50
39_L86_G0.7800.50
99_Q103_K0.7730.49
76_E83_Q0.7700.49
46_I160_E0.7640.48
75_M87_K0.7570.48
112_V116_H0.7560.48
175_L179_A0.7530.47
93_D96_P0.7510.47
48_D78_R0.7490.47
56_K163_K0.7470.47
147_Q150_T0.7450.47
118_L126_I0.7440.47
122_R169_R0.7260.45
34_R38_E0.7210.45
24_I31_E0.7090.43
121_L143_A0.6900.42
130_D149_R0.6880.42
61_A65_A0.6850.41
111_Q170_Q0.6820.41
36_A90_R0.6780.41
28_S83_Q0.6750.40
71_Q95_E0.6740.40
126_I171_I0.6730.40
35_D47_V0.6700.40
44_A50_G0.6700.40
27_V32_I0.6690.40
134_A152_I0.6680.40
82_L172_F0.6640.40
42_L62_D0.6630.39
84_L158_E0.6600.39
132_A152_I0.6590.39
125_L136_V0.6560.39
123_D126_I0.6560.39
46_I63_L0.6480.38
30_S35_D0.6480.38
59_L155_A0.6470.38
21_D24_I0.6460.38
57_I124_R0.6450.38
141_P153_R0.6370.37
126_I156_K0.6350.37
47_V85_I0.6340.37
48_D82_L0.6340.37
79_R82_L0.6330.37
69_L77_G0.6320.37
39_L94_V0.6230.36
104_L150_T0.6220.36
28_S33_K0.6220.36
42_L148_L0.6210.36
113_V132_A0.6170.36
149_R153_R0.6140.35
120_N179_A0.6120.35
59_L62_D0.6120.35
74_K98_R0.6090.35
33_K66_A0.6000.34
31_E58_P0.5990.34
152_I156_K0.5970.34
114_L117_K0.5950.34
124_R128_Q0.5940.34
164_P168_A0.5910.33
87_K108_H0.5910.33
85_I94_V0.5890.33
44_A51_K0.5870.33
95_E157_K0.5860.33
69_L123_D0.5850.33
67_I124_R0.5830.33
41_R139_L0.5790.32
131_D135_E0.5790.32
157_K166_K0.5770.32
33_K86_G0.5760.32
125_L151_L0.5670.31
116_H165_P0.5660.31
70_A97_I0.5630.31
38_E94_V0.5600.31
58_P162_N0.5600.31
76_E86_G0.5570.31
130_D153_R0.5540.30
22_D25_I0.5540.30
29_K37_E0.5520.30
37_E40_K0.5520.30
121_L179_A0.5480.30
127_D142_D0.5450.30
79_R90_R0.5370.29
39_L43_G0.5340.29
56_K104_L0.5320.29
143_A175_L0.5310.29
76_E124_R0.5300.29
103_K108_H0.5290.29
157_K161_G0.5270.28
103_K106_N0.5260.28
68_E135_E0.5250.28
170_Q177_E0.5240.28
43_G66_A0.5230.28
26_W31_E0.5210.28
129_G133_I0.5200.28
151_L163_K0.5190.28
118_L173_Q0.5180.28
30_S33_K0.5170.28
66_A88_M0.5170.28
136_V152_I0.5160.28
29_K97_I0.5150.28
30_S38_E0.5130.27
58_P64_R0.5130.27
36_A86_G0.5110.27
159_K168_A0.5080.27
27_V175_L0.5070.27
116_H122_R0.5050.27
43_G90_R0.5040.27
17_I20_E0.5030.27
60_D75_M0.5010.27
40_K76_E0.5010.27
17_I73_I0.5010.27
24_I134_A0.5000.26
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2p0tA 1 0.8033 100 0.111 Contact Map
4yweA 5 0.3497 20.6 0.95 Contact Map
3e3vA 1 0.5902 9.5 0.957 Contact Map
1wudA 3 0.3716 9.1 0.958 Contact Map
3sfzA 1 0.1093 8.9 0.958 Contact Map
2v9vA 1 0.5738 8.6 0.958 Contact Map
1ichA 1 0.4262 8.4 0.958 Contact Map
1hciA 2 0.4372 7.7 0.959 Contact Map
1lvaA 1 0.5738 7.6 0.959 Contact Map
2e1fA 2 0.4208 7.4 0.959 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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