SYT - ECOLI - GREMLIN Contacts

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SYT - Threonine--tRNA ligase

UniProt:	P0A8M3	Sequences: MPVITLPDGSQRHYDHAVSPMDVALDIGPGLAKACIAGRVNGELVDACDLIENDAQLSIITAKDEEGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVIDNGFYYDVDLDRTLTQEDVEALEKRMHELAEKNYDVIKKKVSWHEARETFANRGESYKVSILDENIAHDDKPGLYFHEEYVDMCRGPHVPNMRFCHHFKLMKTAGAYWRGDSNNKMLQRIYGTAWADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDSQSEYVNELTQKLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVNEVIEKLQQEIRSRSLKQLEE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11001
Length:	642 (620)
Sequences:	3584 (1666)
Seq/√Len:	66.9

ECOLI - SYT
BACSU - SYT1 SYT2
HALSA - SYT
SULSO - SYT

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
499_G	505_K	5.969	1.00
557_E	604_G	3.836	1.00
394_R	443_V	3.804	1.00
551_Q	598_D	3.507	1.00
123_R	126_E	3.453	1.00
85_Q	123_R	3.394	1.00
138_K	169_K	3.352	1.00
131_N	189_N	3.267	1.00
442_A	446_E	3.261	1.00
394_R	447_E	3.208	1.00
41_N	53_N	3.179	1.00
75_C	222_A	3.112	1.00
39_R	58_S	2.979	1.00
252_D	344_G	2.960	1.00
137_K	174_F	2.880	1.00
301_R	305_E	2.868	1.00
494_S	506_V	2.862	1.00
293_V	340_I	2.861	1.00
35_C	59_I	2.773	1.00
491_S	506_V	2.771	1.00
20_P	38_G	2.737	1.00
107_D	213_K	2.719	1.00
146_E	149_A	2.694	1.00
145_R	161_D	2.669	1.00
559_T	569_V	2.650	1.00
526_T	533_F	2.602	1.00
501_D	505_K	2.538	1.00
107_D	155_Y	2.536	1.00
83_I	106_V	2.482	1.00
255_H	267_H	2.461	1.00
85_Q	130_K	2.440	1.00
226_K	230_N	2.421	1.00
78_L	128_A	2.412	1.00
39_R	66_E	2.340	1.00
499_G	503_E	2.330	1.00
78_L	193_C	2.324	1.00
561_K	622_N	2.313	1.00
40_V	55_A	2.277	1.00
423_R	427_R	2.258	1.00
145_R	157_V	2.245	1.00
135_I	174_F	2.227	1.00
74_S	134_V	2.209	1.00
594_L	606_V	2.187	1.00
430_S	433_M	2.136	1.00
224_A	228_A	2.121	1.00
545_M	578_I	2.104	1.00
225_D	228_A	2.100	1.00
78_L	127_L	2.100	1.00
598_D	602_E	2.085	1.00
302_V	305_E	2.076	1.00
574_R	584_E	2.062	1.00
424_P	459_G	2.059	1.00
81_H	175_H	2.053	1.00
540_V	570_K	2.037	1.00
446_E	452_F	2.033	1.00
630_Q	634_S	2.023	1.00
74_S	187_V	2.022	1.00
558_L	621_V	2.016	1.00
284_K	288_Y	1.956	1.00
284_K	406_D	1.953	1.00
252_D	267_H	1.951	1.00
149_A	161_D	1.935	1.00
174_F	179_V	1.934	1.00
439_A	443_V	1.916	1.00
544_I	559_T	1.906	1.00
398_N	447_E	1.904	1.00
559_T	571_A	1.898	1.00
141_W	165_A	1.895	1.00
280_F	410_T	1.877	1.00
22_D	25_L	1.874	1.00
623_E	626_E	1.862	1.00
427_R	431_D	1.859	1.00
548_T	551_Q	1.856	1.00
84_K	178_Y	1.854	1.00
439_A	442_A	1.823	1.00
299_M	336_G	1.820	1.00
284_K	287_E	1.814	1.00
37_A	70_I	1.813	1.00
84_K	153_E	1.810	1.00
58_S	64_D	1.809	1.00
141_W	166_H	1.778	1.00
197_K	233_L	1.772	1.00
269_D	588_R	1.768	1.00
131_N	191_R	1.764	1.00
442_A	454_Y	1.742	1.00
550_S	598_D	1.741	1.00
121_E	197_K	1.737	1.00
90_T	108_L	1.734	1.00
232_Y	236_L	1.717	1.00
567_I	632_I	1.702	0.99
14_Y	26_D	1.701	0.99
72_R	221_T	1.699	0.99
188_P	192_F	1.693	0.99
338_V	509_M	1.692	0.99
428_I	488_S	1.691	0.99
85_Q	177_E	1.691	0.99
108_L	112_L	1.688	0.99
79_L	120_L	1.687	0.99
276_E	279_V	1.687	0.99
146_E	150_N	1.680	0.99
155_Y	213_K	1.672	0.99
556_N	559_T	1.671	0.99
14_Y	18_V	1.668	0.99
45_V	49_D	1.634	0.99
402_R	448_N	1.630	0.99
547_I	578_I	1.619	0.99
280_F	406_D	1.612	0.99
35_C	47_A	1.603	0.99
553_E	556_N	1.601	0.99
269_D	570_K	1.601	0.99
535_T	628_L	1.594	0.99
85_Q	126_E	1.591	0.99
68_L	72_R	1.589	0.99
559_T	563_S	1.586	0.99
557_E	561_K	1.585	0.99
455_Q	458_E	1.571	0.99
81_H	132_Y	1.564	0.99
199_M	236_L	1.549	0.99
12_R	26_D	1.548	0.99
401_I	468_F	1.541	0.99
532_F	589_R	1.540	0.99
535_T	631_E	1.534	0.99
273_I	522_I	1.529	0.99
390_E	436_R	1.524	0.99
84_K	89_H	1.517	0.99
28_G	34_A	1.509	0.99
417_V	477_A	1.508	0.99
41_N	55_A	1.502	0.99
246_K	250_Q	1.500	0.99
23_V	57_L	1.497	0.99
237_E	240_A	1.493	0.99
567_I	628_L	1.490	0.99
21_M	25_L	1.489	0.99
586_T	589_R	1.488	0.99
209_D	212_N	1.482	0.99
562_L	625_I	1.467	0.98
71_I	224_A	1.466	0.98
148_F	172_L	1.454	0.98
599_K	602_E	1.438	0.98
172_L	179_V	1.433	0.98
122_K	125_H	1.431	0.98
27_I	31_L	1.429	0.98
142_H	146_E	1.429	0.98
445_L	466_I	1.420	0.98
343_Q	346_K	1.412	0.98
585_H	593_M	1.404	0.98
595_V	607_A	1.403	0.98
137_K	143_E	1.400	0.98
556_N	573_L	1.398	0.98
297_F	362_H	1.397	0.98
260_A	263_M	1.396	0.98
397_V	466_I	1.395	0.98
133_D	189_N	1.394	0.98
629_Q	633_R	1.391	0.98
469_T	477_A	1.391	0.98
496_S	504_R	1.388	0.98
545_M	593_M	1.385	0.98
203_G	214_M	1.378	0.98
594_L	624_V	1.374	0.98
89_H	109_D	1.374	0.98
586_T	593_M	1.373	0.98
544_I	555_V	1.370	0.98
312_N	426_K	1.367	0.98
24_A	59_I	1.366	0.98
23_V	51_I	1.366	0.98
20_P	45_V	1.361	0.98
366_P	369_S	1.360	0.97
278_E	294_K	1.359	0.97
542_V	628_L	1.357	0.97
100_N	235_R	1.350	0.97
134_V	175_H	1.350	0.97
38_G	59_I	1.348	0.97
165_A	168_D	1.347	0.97
301_R	326_E	1.337	0.97
554_Y	596_C	1.321	0.97
94_I	159_I	1.320	0.97
15_D	18_V	1.313	0.97
543_V	585_H	1.313	0.97
158_S	207_R	1.305	0.97
92_M	153_E	1.301	0.97
560_Q	564_N	1.301	0.97
321_S	324_N	1.300	0.97
247_I	251_L	1.294	0.97
51_I	55_A	1.292	0.97
346_K	350_D	1.291	0.97
269_D	540_V	1.288	0.97
305_E	311_D	1.288	0.97
626_E	630_Q	1.288	0.97
266_W	522_I	1.276	0.96
561_K	604_G	1.276	0.96
19_S	22_D	1.274	0.96
139_V	172_L	1.273	0.96
354_R	396_E	1.270	0.96
147_T	179_V	1.269	0.96
36_I	70_I	1.267	0.96
145_R	160_L	1.264	0.96
422_T	454_Y	1.261	0.96
91_K	107_D	1.260	0.96
498_V	504_R	1.259	0.96
542_V	567_I	1.253	0.96
126_E	130_K	1.249	0.96
393_I	485_L	1.247	0.96
44_L	60_I	1.244	0.96
113_T	117_V	1.243	0.96
67_G	224_A	1.237	0.96
422_T	442_A	1.234	0.96
543_V	588_R	1.226	0.95
62_A	68_L	1.226	0.95
286_K	563_S	1.226	0.95
627_K	631_E	1.224	0.95
39_R	44_L	1.222	0.95
199_M	221_T	1.221	0.95
140_S	143_E	1.213	0.95
92_M	106_V	1.213	0.95
549_D	552_S	1.211	0.95
281_V	407_M	1.211	0.95
49_D	171_G	1.210	0.95
540_V	543_V	1.210	0.95
620_D	623_E	1.210	0.95
228_A	231_A	1.202	0.95
49_D	136_K	1.199	0.95
592_Y	631_E	1.198	0.95
241_K	530_A	1.197	0.95
24_A	27_I	1.196	0.95
68_L	71_I	1.195	0.95
139_V	147_T	1.194	0.95
379_F	517_S	1.190	0.95
34_A	63_K	1.186	0.94
625_I	629_Q	1.184	0.94
346_K	353_L	1.181	0.94
557_E	560_Q	1.179	0.94
202_A	214_M	1.171	0.94
272_T	568_R	1.169	0.94
73_H	96_P	1.168	0.94
58_S	66_E	1.167	0.94
556_N	571_A	1.166	0.94
547_I	579_G	1.164	0.94
561_K	625_I	1.163	0.94
338_V	495_A	1.157	0.94
143_E	146_E	1.156	0.94
288_Y	406_D	1.149	0.93
360_S	378_G	1.148	0.93
391_E	500_E	1.148	0.93
252_D	255_H	1.146	0.93
321_S	326_E	1.145	0.93
274_F	294_K	1.142	0.93
427_R	435_D	1.141	0.93
288_Y	403_L	1.140	0.93
94_I	98_I	1.135	0.93
565_A	629_Q	1.133	0.93
257_Q	339_Q	1.132	0.93
132_Y	190_M	1.131	0.93
38_G	45_V	1.128	0.93
40_V	57_L	1.128	0.93
281_V	285_L	1.125	0.93
69_E	97_V	1.124	0.93
561_K	565_A	1.123	0.93
608_V	624_V	1.122	0.93
272_T	276_E	1.120	0.93
287_E	564_N	1.115	0.92
237_E	241_K	1.114	0.92
133_D	191_R	1.108	0.92
580_F	584_E	1.104	0.92
132_Y	177_E	1.104	0.92
431_D	435_D	1.102	0.92
610_T	613_G	1.102	0.92
130_K	177_E	1.101	0.92
73_H	77_H	1.098	0.92
136_K	171_G	1.097	0.92
553_E	557_E	1.096	0.92
344_G	350_D	1.091	0.92
134_V	187_V	1.091	0.92
402_R	406_D	1.090	0.92
561_K	621_V	1.085	0.91
238_E	241_K	1.081	0.91
62_A	71_I	1.080	0.91
274_F	278_E	1.079	0.91
532_F	611_R	1.078	0.91
227_K	230_N	1.078	0.91
279_V	283_S	1.077	0.91
20_P	57_L	1.076	0.91
231_A	234_Q	1.074	0.91
255_H	343_Q	1.074	0.91
405_Y	409_S	1.073	0.91
20_P	59_I	1.069	0.91
164_I	170_P	1.069	0.91
18_V	22_D	1.068	0.91
257_Q	267_H	1.068	0.91
433_M	488_S	1.067	0.91
108_L	216_Q	1.066	0.91
619_M	624_V	1.065	0.91
98_I	103_Y	1.062	0.90
547_I	551_Q	1.062	0.90
71_I	75_C	1.059	0.90
163_N	207_R	1.058	0.90
40_V	51_I	1.058	0.90
117_V	220_G	1.054	0.90
551_Q	601_V	1.046	0.90
398_N	448_N	1.046	0.90
90_T	106_V	1.043	0.90
21_M	32_A	1.041	0.90
112_L	218_I	1.041	0.90
555_V	571_A	1.039	0.89
594_L	608_V	1.037	0.89
62_A	224_A	1.037	0.89
74_S	78_L	1.037	0.89
338_V	387_F	1.034	0.89
275_R	279_V	1.034	0.89
277_L	411_F	1.032	0.89
31_L	59_I	1.032	0.89
41_N	56_Q	1.031	0.89
93_A	153_E	1.027	0.89
561_K	564_N	1.027	0.89
277_L	515_L	1.025	0.89
614_K	617_G	1.025	0.89
470_L	480_C	1.024	0.89
300_D	325_R	1.022	0.89
310_W	328_C	1.021	0.89
544_I	558_L	1.019	0.89
419_K	469_T	1.016	0.88
619_M	627_K	1.016	0.88
78_L	134_V	1.015	0.88
40_V	49_D	1.014	0.88
293_V	337_H	1.012	0.88
556_N	560_Q	1.011	0.88
297_F	360_S	1.008	0.88
132_Y	175_H	1.000	0.88
276_E	568_R	1.000	0.88
260_A	299_M	0.997	0.87
386_I	400_C	0.996	0.87
234_Q	237_E	0.996	0.87
285_L	358_F	0.992	0.87
40_V	45_V	0.991	0.87
599_K	603_S	0.990	0.87
60_I	70_I	0.989	0.87
225_D	230_N	0.988	0.87
301_R	310_W	0.987	0.87
418_V	450_I	0.986	0.87
83_I	90_T	0.986	0.87
68_L	224_A	0.985	0.87
549_D	575_N	0.984	0.87
376_V	379_F	0.984	0.87
71_I	222_A	0.983	0.87
312_N	428_I	0.981	0.87
160_L	170_P	0.978	0.86
273_I	276_E	0.974	0.86
25_L	32_A	0.971	0.86
546_N	555_V	0.965	0.86
443_V	447_E	0.958	0.85
598_D	601_V	0.958	0.85
142_H	166_H	0.956	0.85
293_V	355_M	0.953	0.85
271_W	294_K	0.951	0.85
86_L	120_L	0.950	0.85
164_I	167_D	0.950	0.85
121_E	125_H	0.949	0.85
114_Q	118_E	0.948	0.85
24_A	32_A	0.945	0.84
532_F	586_T	0.943	0.84
164_I	168_D	0.941	0.84
440_D	485_L	0.941	0.84
227_K	231_A	0.940	0.84
131_N	190_M	0.940	0.84
18_V	51_I	0.939	0.84
282_R	292_E	0.938	0.84
578_I	581_K	0.935	0.84
87_W	110_R	0.933	0.84
28_G	31_L	0.932	0.84
577_K	580_F	0.931	0.84
156_K	180_D	0.927	0.83
622_N	626_E	0.926	0.83
137_K	172_L	0.924	0.83
304_W	336_G	0.922	0.83
77_H	96_P	0.920	0.83
160_L	164_I	0.919	0.83
96_P	186_H	0.916	0.83
37_A	60_I	0.915	0.82
51_I	54_D	0.911	0.82
535_T	632_I	0.911	0.82
17_A	50_L	0.908	0.82
544_I	571_A	0.905	0.82
108_L	111_T	0.903	0.82
77_H	186_H	0.903	0.82
91_K	154_S	0.902	0.82
94_I	207_R	0.902	0.82
72_R	222_A	0.900	0.81
71_I	128_A	0.898	0.81
275_R	278_E	0.897	0.81
189_N	192_F	0.893	0.81
132_Y	176_E	0.892	0.81
565_A	625_I	0.889	0.81
73_H	186_H	0.886	0.80
435_D	439_A	0.886	0.80
84_K	90_T	0.885	0.80
554_Y	558_L	0.884	0.80
542_V	594_L	0.884	0.80
60_I	64_D	0.884	0.80
182_C	186_H	0.883	0.80
389_T	500_E	0.883	0.80
532_F	612_R	0.882	0.80
489_L	492_R	0.879	0.80
19_S	50_L	0.877	0.80
361_C	515_L	0.873	0.79
106_V	112_L	0.872	0.79
357_E	380_T	0.868	0.79
604_G	621_V	0.868	0.79
355_M	384_A	0.867	0.79
604_G	622_N	0.867	0.79
112_L	118_E	0.867	0.79
94_I	153_E	0.866	0.79
417_V	453_E	0.865	0.79
24_A	28_G	0.865	0.79
401_I	466_I	0.864	0.79
422_T	459_G	0.862	0.79
247_I	250_Q	0.861	0.78
141_W	145_R	0.861	0.78
458_E	467_E	0.860	0.78
276_E	632_I	0.859	0.78
567_I	629_Q	0.858	0.78
552_S	573_L	0.857	0.78
285_L	356_A	0.857	0.78
605_K	620_D	0.855	0.78
288_Y	402_R	0.855	0.78
419_K	455_Q	0.854	0.78
234_Q	241_K	0.853	0.78
613_G	616_L	0.853	0.78
145_R	149_A	0.851	0.78
263_M	378_G	0.850	0.78
401_I	448_N	0.849	0.77
210_S	366_P	0.848	0.77
374_M	523_G	0.847	0.77
281_V	358_F	0.847	0.77
544_I	621_V	0.845	0.77
472_D	476_R	0.844	0.77
158_S	212_N	0.841	0.77
546_N	571_A	0.839	0.77
544_I	596_C	0.839	0.77
72_R	224_A	0.838	0.77
27_I	32_A	0.838	0.77
291_Q	355_M	0.837	0.76
14_Y	17_A	0.836	0.76
607_A	615_D	0.835	0.76
199_M	233_L	0.835	0.76
233_L	236_L	0.834	0.76
117_V	198_L	0.833	0.76
73_H	182_C	0.833	0.76
14_Y	23_V	0.832	0.76
389_T	392_Q	0.832	0.76
210_S	213_K	0.831	0.76
71_I	187_V	0.830	0.76
423_R	431_D	0.828	0.76
109_D	213_K	0.828	0.76
543_V	570_K	0.827	0.76
20_P	23_V	0.826	0.76
234_Q	238_E	0.826	0.76
104_Y	156_K	0.825	0.75
24_A	31_L	0.825	0.75
400_C	510_I	0.823	0.75
85_Q	127_L	0.823	0.75
554_Y	601_V	0.823	0.75
420_L	485_L	0.822	0.75
18_V	23_V	0.820	0.75
96_P	182_C	0.819	0.75
287_E	563_S	0.819	0.75
148_F	160_L	0.818	0.75
619_M	623_E	0.816	0.75
409_S	414_E	0.813	0.74
576_E	584_E	0.813	0.74
572_D	581_K	0.813	0.74
608_V	619_M	0.812	0.74
76_A	183_R	0.811	0.74
306_K	493_L	0.811	0.74
39_R	60_I	0.811	0.74
414_E	471_Y	0.810	0.74
413_F	487_F	0.810	0.74
397_V	483_V	0.810	0.74
546_N	552_S	0.805	0.74
285_L	400_C	0.805	0.74
615_D	618_S	0.804	0.74
104_Y	180_D	0.803	0.73
382_D	478_W	0.801	0.73
422_T	455_Q	0.800	0.73
438_E	456_L	0.799	0.73
345_L	504_R	0.798	0.73
302_V	306_K	0.795	0.73
381_Q	513_A	0.795	0.73
100_N	232_Y	0.794	0.73
110_R	116_D	0.794	0.73
253_L	533_F	0.793	0.73
357_E	361_C	0.793	0.73
155_Y	212_N	0.791	0.72
89_H	108_L	0.791	0.72
77_H	182_C	0.791	0.72
339_Q	342_N	0.790	0.72
110_R	119_A	0.788	0.72
280_F	284_K	0.788	0.72
395_D	399_G	0.787	0.72
253_L	526_T	0.786	0.72
533_F	538_A	0.786	0.72
266_W	519_E	0.786	0.72
43_E	49_D	0.784	0.72
83_I	120_L	0.783	0.72
535_T	592_Y	0.782	0.71
624_V	628_L	0.782	0.71
420_L	442_A	0.781	0.71
488_S	491_S	0.778	0.71
418_V	468_F	0.778	0.71
49_D	52_E	0.775	0.71
420_L	445_L	0.775	0.71
81_H	177_E	0.774	0.71
80_G	178_Y	0.774	0.71
20_P	47_A	0.773	0.71
77_H	95_G	0.772	0.70
37_A	44_L	0.771	0.70
256_M	264_V	0.770	0.70
235_R	474_L	0.769	0.70
76_A	97_V	0.767	0.70
291_Q	353_L	0.767	0.70
251_L	588_R	0.760	0.69
472_D	479_Q	0.759	0.69
251_L	532_F	0.759	0.69
116_D	119_A	0.756	0.69
95_G	184_G	0.756	0.69
31_L	61_T	0.755	0.69
382_D	472_D	0.755	0.69
16_H	52_E	0.755	0.69
64_D	67_G	0.754	0.69
435_D	438_E	0.753	0.69
342_N	494_S	0.750	0.68
555_V	596_C	0.749	0.68
546_N	551_Q	0.748	0.68
513_A	517_S	0.747	0.68
587_L	611_R	0.746	0.68
204_A	214_M	0.746	0.68
73_H	95_G	0.742	0.67
95_G	104_Y	0.741	0.67
304_W	424_P	0.740	0.67
407_M	513_A	0.739	0.67
93_A	215_L	0.739	0.67
542_V	569_V	0.738	0.67
28_G	32_A	0.738	0.67
38_G	57_L	0.737	0.67
79_L	83_I	0.733	0.67
127_L	130_K	0.731	0.66
93_A	159_I	0.730	0.66
497_Y	505_K	0.728	0.66
75_C	196_F	0.727	0.66
562_L	621_V	0.726	0.66
164_I	169_K	0.726	0.66
558_L	562_L	0.726	0.66
287_E	406_D	0.726	0.66
342_N	495_A	0.724	0.66
315_D	426_K	0.724	0.66
570_K	590_V	0.722	0.65
404_V	413_F	0.722	0.65
299_M	328_C	0.722	0.65
320_T	364_N	0.721	0.65
607_A	618_S	0.720	0.65
621_V	625_I	0.719	0.65
147_T	174_F	0.717	0.65
535_T	624_V	0.713	0.64
264_V	378_G	0.713	0.64
382_D	479_Q	0.712	0.64
130_K	190_M	0.711	0.64
345_L	498_V	0.711	0.64
361_C	400_C	0.711	0.64
284_K	410_T	0.710	0.64
75_C	78_L	0.709	0.64
288_Y	399_G	0.708	0.64
592_Y	624_V	0.707	0.64
630_Q	633_R	0.707	0.64
96_P	104_Y	0.707	0.64
546_N	578_I	0.707	0.64
421_S	455_Q	0.706	0.64
68_L	221_T	0.705	0.63
123_R	130_K	0.702	0.63
31_L	35_C	0.699	0.63
567_I	625_I	0.698	0.63
247_I	589_R	0.698	0.63
125_H	129_E	0.696	0.62
63_K	228_A	0.696	0.62
231_A	235_R	0.694	0.62
83_I	112_L	0.692	0.62
112_L	153_E	0.692	0.62
419_K	477_A	0.692	0.62
180_D	186_H	0.691	0.62
248_G	254_Y	0.691	0.62
62_A	72_R	0.691	0.62
358_F	513_A	0.690	0.62
139_V	145_R	0.690	0.62
157_V	161_D	0.687	0.61
354_R	399_G	0.686	0.61
274_F	380_T	0.685	0.61
34_A	61_T	0.685	0.61
80_G	104_Y	0.685	0.61
156_K	186_H	0.685	0.61
155_Y	214_M	0.684	0.61
396_E	399_G	0.683	0.61
141_W	163_N	0.683	0.61
562_L	567_I	0.682	0.61
141_W	164_I	0.681	0.61
285_L	515_L	0.681	0.61
14_Y	51_I	0.680	0.61
301_R	319_T	0.679	0.61
36_I	62_A	0.678	0.60
178_Y	181_M	0.677	0.60
263_M	299_M	0.677	0.60
51_I	57_L	0.677	0.60
154_S	213_K	0.676	0.60
422_T	458_E	0.675	0.60
141_W	170_P	0.675	0.60
128_A	196_F	0.675	0.60
173_Y	185_P	0.673	0.60
141_W	168_D	0.672	0.60
99_D	471_Y	0.672	0.60
404_V	468_F	0.672	0.60
472_D	478_W	0.671	0.60
144_A	170_P	0.671	0.60
546_N	596_C	0.671	0.60
95_G	186_H	0.668	0.59
423_R	438_E	0.665	0.59
361_C	380_T	0.663	0.59
313_Y	467_E	0.661	0.59
268_N	355_M	0.661	0.59
304_W	459_G	0.661	0.59
139_V	144_A	0.660	0.58
437_A	487_F	0.660	0.58
21_M	47_A	0.659	0.58
318_F	364_N	0.659	0.58
395_D	398_N	0.658	0.58
605_K	618_S	0.658	0.58
310_W	408_Y	0.658	0.58
163_N	167_D	0.657	0.58
107_D	154_S	0.657	0.58
400_C	483_V	0.656	0.58
198_L	218_I	0.656	0.58
284_K	403_L	0.656	0.58
230_N	234_Q	0.655	0.58
95_G	180_D	0.655	0.58
100_N	221_T	0.654	0.58
137_K	179_V	0.653	0.58
548_T	598_D	0.653	0.58
112_L	216_Q	0.653	0.58
96_P	156_K	0.652	0.57
35_C	61_T	0.651	0.57
118_E	122_K	0.651	0.57
405_Y	416_I	0.650	0.57
400_C	404_V	0.649	0.57
313_Y	316_A	0.649	0.57
158_S	206_W	0.648	0.57
610_T	631_E	0.648	0.57
292_E	408_Y	0.647	0.57
147_T	172_L	0.646	0.57
98_I	159_I	0.646	0.57
52_E	55_A	0.645	0.57
210_S	214_M	0.645	0.57
463_G	487_F	0.642	0.56
98_I	219_Y	0.642	0.56
454_Y	459_G	0.641	0.56
522_I	526_T	0.641	0.56
73_H	104_Y	0.639	0.56
425_E	457_G	0.639	0.56
81_H	134_V	0.639	0.56
540_V	569_V	0.638	0.56
428_I	492_R	0.638	0.56
44_L	70_I	0.638	0.56
289_Q	563_S	0.637	0.56
139_V	143_E	0.637	0.56
290_Y	400_C	0.636	0.56
535_T	567_I	0.635	0.55
257_Q	265_F	0.632	0.55
454_Y	458_E	0.632	0.55
319_T	328_C	0.632	0.55
595_V	618_S	0.631	0.55
128_A	191_R	0.630	0.55
552_S	598_D	0.630	0.55
81_H	127_L	0.630	0.55
616_L	619_M	0.629	0.55
626_E	629_Q	0.628	0.55
275_R	292_E	0.628	0.55
382_D	524_I	0.628	0.55
104_Y	186_H	0.628	0.55
46_D	185_P	0.627	0.55
297_F	378_G	0.626	0.54
586_T	612_R	0.626	0.54
523_G	526_T	0.625	0.54
275_R	286_K	0.622	0.54
62_A	67_G	0.622	0.54
272_T	275_R	0.621	0.54
10_S	27_I	0.621	0.54
12_R	23_V	0.621	0.54
390_E	505_K	0.621	0.54
71_I	221_T	0.620	0.54
21_M	48_C	0.620	0.54
524_I	528_E	0.619	0.54
337_H	487_F	0.619	0.54
563_S	569_V	0.618	0.54
585_H	590_V	0.617	0.53
198_L	220_G	0.617	0.53
78_L	195_H	0.617	0.53
122_K	227_K	0.616	0.53
557_E	601_V	0.615	0.53
558_L	561_K	0.615	0.53
18_V	50_L	0.614	0.53
94_I	103_Y	0.614	0.53
136_K	173_Y	0.613	0.53
92_M	148_F	0.613	0.53
606_V	624_V	0.613	0.53
362_H	408_Y	0.612	0.53
251_L	533_F	0.612	0.53
468_F	481_G	0.611	0.53
98_I	207_R	0.611	0.53
421_S	489_L	0.609	0.52
329_I	473_C	0.609	0.52
70_I	74_S	0.609	0.52
77_H	104_Y	0.609	0.52
433_M	491_S	0.608	0.52
361_C	374_M	0.608	0.52
382_D	476_R	0.607	0.52
23_V	26_D	0.607	0.52
490_P	509_M	0.607	0.52
119_A	122_K	0.606	0.52
281_V	515_L	0.606	0.52
554_Y	605_K	0.606	0.52
240_A	246_K	0.605	0.52
422_T	445_L	0.605	0.52
360_S	380_T	0.605	0.52
455_Q	469_T	0.604	0.52
195_H	226_K	0.603	0.52
95_G	182_C	0.603	0.52
432_E	435_D	0.601	0.51
60_I	66_E	0.600	0.51
381_Q	517_S	0.600	0.51
611_R	617_G	0.600	0.51
27_I	59_I	0.599	0.51
341_F	346_K	0.598	0.51
86_L	123_R	0.598	0.51
328_C	336_G	0.597	0.51
283_S	566_G	0.596	0.51
278_E	337_H	0.595	0.51
122_K	126_E	0.595	0.51
96_P	184_G	0.594	0.51
141_W	167_D	0.593	0.51
319_T	489_L	0.593	0.51
542_V	596_C	0.592	0.50
77_H	184_G	0.591	0.50
483_V	510_I	0.591	0.50
45_V	55_A	0.590	0.50
548_T	575_N	0.590	0.50
166_H	170_P	0.590	0.50
137_K	147_T	0.590	0.50
43_E	146_E	0.589	0.50
17_A	52_E	0.589	0.50
312_N	488_S	0.588	0.50
142_H	145_R	0.587	0.50
445_L	452_F	0.587	0.50
94_I	183_R	0.587	0.50
459_G	480_C	0.587	0.50
391_E	436_R	0.584	0.49
592_Y	610_T	0.583	0.49
353_L	389_T	0.583	0.49
195_H	229_L	0.583	0.49
77_H	156_K	0.582	0.49
552_S	556_N	0.581	0.49
9_G	31_L	0.580	0.49
252_D	269_D	0.580	0.49
66_E	69_E	0.580	0.49
235_R	475_D	0.579	0.49
10_S	31_L	0.579	0.49
613_G	617_G	0.578	0.49
73_H	156_K	0.578	0.49
558_L	565_A	0.575	0.48
261_P	325_R	0.574	0.48
586_T	609_R	0.574	0.48
596_C	606_V	0.574	0.48
292_E	358_F	0.573	0.48
159_I	163_N	0.573	0.48
79_L	218_I	0.572	0.48
543_V	596_C	0.572	0.48
12_R	31_L	0.572	0.48
137_K	140_S	0.571	0.48
384_A	489_L	0.571	0.48
285_L	289_Q	0.568	0.48
485_L	510_I	0.568	0.48
75_C	193_C	0.567	0.47
285_L	361_C	0.567	0.47
24_A	38_G	0.565	0.47
294_K	360_S	0.565	0.47
408_Y	470_L	0.565	0.47
114_Q	216_Q	0.564	0.47
72_R	196_F	0.564	0.47
275_R	282_R	0.563	0.47
156_K	182_C	0.563	0.47
107_D	214_M	0.563	0.47
290_Y	512_R	0.563	0.47
574_R	577_K	0.563	0.47
515_L	518_M	0.563	0.47
10_S	26_D	0.563	0.47
543_V	590_V	0.561	0.47
251_L	538_A	0.561	0.47
305_E	326_E	0.560	0.47
341_F	509_M	0.560	0.47
406_D	410_T	0.560	0.47
306_K	489_L	0.559	0.47
95_G	156_K	0.559	0.47
133_D	190_M	0.559	0.47
20_P	37_A	0.559	0.47
424_P	480_C	0.558	0.46
163_N	166_H	0.557	0.46
577_K	583_R	0.557	0.46
310_W	314_K	0.556	0.46
440_D	444_A	0.556	0.46
142_H	167_D	0.556	0.46
371_H	374_M	0.556	0.46
272_T	286_K	0.556	0.46
393_I	397_V	0.556	0.46
298_M	320_T	0.555	0.46
565_A	626_E	0.554	0.46
87_W	116_D	0.554	0.46
411_F	521_F	0.554	0.46
235_R	471_Y	0.553	0.46
263_M	297_F	0.552	0.46
292_E	481_G	0.552	0.46
92_M	178_Y	0.551	0.46
238_E	242_R	0.551	0.46
470_L	477_A	0.551	0.46
20_P	50_L	0.548	0.45
281_V	356_A	0.548	0.45
278_E	518_M	0.548	0.45
610_T	617_G	0.547	0.45
186_H	219_Y	0.547	0.45
230_N	614_K	0.547	0.45
251_L	590_V	0.546	0.45
401_I	420_L	0.546	0.45
70_I	188_P	0.545	0.45
65_E	453_E	0.545	0.45
231_A	475_D	0.545	0.45
610_T	616_L	0.545	0.45
281_V	361_C	0.545	0.45
145_R	164_I	0.545	0.45
361_C	518_M	0.544	0.45
50_L	53_N	0.544	0.45
238_E	530_A	0.544	0.45
298_M	327_Y	0.544	0.45
81_H	190_M	0.542	0.45
285_L	382_D	0.542	0.45
18_V	26_D	0.542	0.45
93_A	158_S	0.542	0.45
125_H	226_K	0.542	0.45
401_I	470_L	0.541	0.44
210_S	369_S	0.541	0.44
62_A	187_V	0.541	0.44
145_R	163_N	0.540	0.44
209_D	213_K	0.540	0.44
172_L	178_Y	0.539	0.44
260_A	297_F	0.536	0.44
252_D	346_K	0.535	0.44
589_R	612_R	0.535	0.44
301_R	328_C	0.535	0.44
174_F	178_Y	0.535	0.44
381_Q	479_Q	0.535	0.44
479_Q	524_I	0.534	0.44
361_C	493_L	0.534	0.44
628_L	632_I	0.534	0.44
362_H	378_G	0.534	0.44
23_V	54_D	0.534	0.44
43_E	53_N	0.533	0.43
286_K	292_E	0.533	0.43
340_I	487_F	0.532	0.43
75_C	221_T	0.532	0.43
337_H	387_F	0.532	0.43
433_M	436_R	0.532	0.43
417_V	469_T	0.532	0.43
421_S	469_T	0.532	0.43
607_A	616_L	0.531	0.43
98_I	183_R	0.531	0.43
187_V	195_H	0.529	0.43
87_W	119_A	0.528	0.43
328_C	408_Y	0.528	0.43
267_H	343_Q	0.527	0.43
104_Y	182_C	0.527	0.43
130_K	176_E	0.526	0.43
285_L	384_A	0.526	0.43
479_Q	517_S	0.526	0.43
424_P	454_Y	0.525	0.43
46_D	49_D	0.525	0.43
81_H	85_Q	0.525	0.43
282_R	358_F	0.524	0.42
316_A	366_P	0.523	0.42
404_V	514_I	0.523	0.42
616_L	627_K	0.523	0.42
544_I	606_V	0.523	0.42
436_R	440_D	0.522	0.42
278_E	358_F	0.522	0.42
65_E	69_E	0.520	0.42
98_I	214_M	0.520	0.42
476_R	479_Q	0.519	0.42
73_H	184_G	0.518	0.42
419_K	453_E	0.517	0.42
242_R	530_A	0.515	0.41
535_T	594_L	0.515	0.41
299_M	470_L	0.515	0.41
42_G	58_S	0.514	0.41
274_F	361_C	0.513	0.41
538_A	590_V	0.511	0.41
478_W	481_G	0.511	0.41
140_S	171_G	0.511	0.41
398_N	402_R	0.511	0.41
389_T	497_Y	0.511	0.41
130_K	133_D	0.510	0.41
255_H	265_F	0.510	0.41
90_T	112_L	0.510	0.41
84_K	134_V	0.510	0.41
139_V	157_V	0.509	0.41
472_D	524_I	0.509	0.41
430_S	488_S	0.508	0.41
607_A	617_G	0.508	0.41
274_F	360_S	0.508	0.41
305_E	310_W	0.507	0.40
295_G	355_M	0.506	0.40
393_I	440_D	0.506	0.40
109_D	112_L	0.504	0.40
109_D	202_A	0.503	0.40
259_E	306_K	0.503	0.40
310_W	319_T	0.502	0.40
358_F	518_M	0.502	0.40
543_V	578_I	0.501	0.40
620_D	625_I	0.501	0.40
442_A	456_L	0.501	0.40
149_A	154_S	0.500	0.40

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1qf6A	1	0.9984	100	0.344	Contact Map
1nyrA	2	0.9891	100	0.366	Contact Map
4hwtA	2	0.6231	100	0.654	Contact Map
1evlA	2	0.6246	100	0.655	Contact Map
3uh0A	2	0.6184	100	0.656	Contact Map
3a32A	2	0.6231	100	0.669	Contact Map
3qneA	2	0.6558	100	0.719	Contact Map
1atiA	2	0.5607	100	0.723	Contact Map
2zt5A	2	0.5561	100	0.724	Contact Map
2j3lA	2	0.6293	100	0.725	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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