GREMLIN Database
YCGN - UPF0260 protein YcgN
UniProt: P0A8L5 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13895
Length: 153 (141)
Sequences: 815 (498)
Seq/√Len: 42.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
15_K24_E4.6841.00
67_N70_R4.0491.00
41_M46_D3.9651.00
52_N144_H3.7221.00
13_Q106_D3.5911.00
122_H129_R2.9551.00
115_T120_A2.7011.00
112_P118_K2.6941.00
20_M101_L2.5051.00
100_L106_D2.4391.00
108_P115_T2.3991.00
67_N74_F2.3781.00
10_P13_Q2.3111.00
16_T19_E2.1590.99
117_S123_G2.1400.99
131_I148_K2.0970.99
120_A124_E2.0850.99
115_T121_M2.0020.99
60_I132_A1.9660.99
33_G72_F1.9310.99
100_L105_K1.9240.99
16_T24_E1.8240.98
8_D15_K1.8020.98
99_R103_E1.7390.98
109_A120_A1.6970.97
28_L97_A1.6540.97
34_Q126_I1.6010.96
122_H127_S1.5850.96
85_N89_F1.5760.96
85_N92_L1.4960.94
57_Q67_N1.4950.94
58_L128_V1.4700.94
63_C129_R1.4640.94
15_K20_M1.4400.93
100_L108_P1.3750.91
63_C122_H1.3740.91
70_R74_F1.3610.91
95_T100_L1.3480.90
18_D87_P1.2930.88
10_P14_S1.2920.88
34_Q94_M1.2670.87
121_M124_E1.2410.86
21_S27_S1.2280.86
120_A123_G1.2180.85
22_D80_K1.1920.84
15_K19_E1.1890.84
72_F92_L1.1860.84
72_F80_K1.1840.83
10_P27_S1.1740.83
89_F92_L1.1520.82
64_Q118_K1.1460.81
41_M48_I1.1260.80
134_K137_E1.1200.80
54_A58_L1.1140.79
8_D27_S1.0980.78
70_R73_E1.0890.78
27_S101_L1.0810.77
56_R75_E1.0400.75
40_L49_Y1.0390.75
48_I90_E1.0300.74
16_T101_L1.0230.73
13_Q114_L1.0180.73
13_Q101_L1.0160.73
112_P120_A1.0140.73
79_I89_F1.0050.72
119_A129_R0.9950.71
39_K50_F0.9930.71
38_H49_Y0.9900.71
52_N138_V0.9850.70
89_F146_L0.9720.69
63_C127_S0.9710.69
115_T124_E0.9580.68
56_R135_E0.9470.67
20_M27_S0.9450.67
49_Y145_I0.9440.67
138_V141_W0.9370.67
57_Q135_E0.9240.65
9_V27_S0.9150.65
33_G58_L0.9130.65
34_Q128_V0.9130.65
53_V141_W0.9120.64
95_T126_I0.9100.64
11_F24_E0.9010.64
56_R134_K0.8930.63
79_I92_L0.8830.62
82_T88_T0.8820.62
119_A123_G0.8720.61
108_P126_I0.8710.61
15_K101_L0.8440.58
54_A57_Q0.8360.58
86_L89_F0.8330.57
135_E142_Q0.8260.57
21_S97_A0.8250.57
117_S120_A0.8230.56
91_W115_T0.8040.55
130_H148_K0.8040.55
11_F15_K0.7990.54
16_T20_M0.7850.53
87_P102_A0.7830.53
52_N131_I0.7830.53
53_V81_L0.7830.53
50_F148_K0.7750.52
27_S106_D0.7750.52
38_H58_L0.7670.51
101_L106_D0.7660.51
59_N119_A0.7630.51
33_G54_A0.7530.50
109_A114_L0.7430.49
56_R136_S0.7410.49
37_L128_V0.7360.48
28_L101_L0.7330.48
76_P95_T0.7330.48
44_D133_V0.7240.47
73_E80_K0.7160.46
94_M146_L0.7070.46
23_A44_D0.7040.45
81_L89_F0.7040.45
97_A101_L0.6990.45
97_A115_T0.6930.44
138_V144_H0.6900.44
61_K129_R0.6840.44
105_K108_P0.6830.43
41_M121_M0.6780.43
38_H90_E0.6780.43
56_R74_F0.6780.43
112_P122_H0.6760.43
9_V13_Q0.6750.43
61_K130_H0.6730.42
57_Q74_F0.6680.42
82_T130_H0.6600.41
50_F138_V0.6600.41
38_H92_L0.6600.41
128_V132_A0.6570.41
117_S121_M0.6480.40
115_T118_K0.6420.40
43_E83_R0.6370.39
51_T100_L0.6300.39
100_L115_T0.6300.39
64_Q73_E0.6270.38
66_R74_F0.6210.38
80_K86_L0.6100.37
11_F19_E0.6090.37
24_E126_I0.6050.36
118_K121_M0.6000.36
50_F131_I0.5980.36
69_E73_E0.5960.36
43_E141_W0.5940.35
38_H89_F0.5940.35
31_G58_L0.5940.35
106_D114_L0.5880.35
125_R130_H0.5790.34
42_D84_E0.5780.34
83_R101_L0.5740.34
72_F79_I0.5730.34
85_N90_E0.5730.34
9_V14_S0.5730.34
52_N141_W0.5720.34
46_D97_A0.5720.34
48_I119_A0.5710.34
79_I131_I0.5710.34
101_L115_T0.5670.33
24_E33_G0.5670.33
15_K27_S0.5670.33
92_L101_L0.5650.33
82_T85_N0.5600.33
128_V131_I0.5600.33
41_M90_E0.5570.32
67_N73_E0.5550.32
52_N140_D0.5540.32
54_A66_R0.5520.32
12_W17_L0.5520.32
48_I80_K0.5490.32
54_A77_D0.5440.31
80_K83_R0.5440.31
16_T62_T0.5440.31
99_R105_K0.5420.31
121_M126_I0.5420.31
82_T86_L0.5410.31
46_D121_M0.5400.31
52_N148_K0.5400.31
22_D123_G0.5390.31
80_K92_L0.5360.31
90_E136_S0.5350.31
60_I69_E0.5340.30
95_T106_D0.5340.30
72_F89_F0.5330.30
66_R136_S0.5330.30
22_D144_H0.5320.30
52_N133_V0.5280.30
73_E140_D0.5280.30
21_S84_E0.5260.30
39_K77_D0.5250.30
14_S20_M0.5240.30
53_V137_E0.5220.30
17_L101_L0.5190.29
19_E24_E0.5160.29
21_S94_M0.5140.29
102_A105_K0.5140.29
132_A148_K0.5140.29
60_I130_H0.5140.29
46_D53_V0.5120.29
86_L101_L0.5120.29
114_L136_S0.5120.29
90_E103_E0.5110.29
38_H142_Q0.5110.29
60_I63_C0.5100.29
57_Q141_W0.5080.28
34_Q41_M0.5070.28
95_T102_A0.5060.28
40_L51_T0.5030.28
129_R132_A0.5030.28
17_L97_A0.5000.28
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2bs2B 1 0.3399 5.6 0.97 Contact Map
4omfG 2 0.5163 4.8 0.971 Contact Map
2ee1A 1 0.2484 4.4 0.971 Contact Map
2zvsA 1 0.5033 4.3 0.971 Contact Map
1gteA 4 0.4967 4.3 0.971 Contact Map
2epbA 1 0.2484 4.1 0.971 Contact Map
2licA 1 0.1111 3.5 0.972 Contact Map
3tr3A 2 0.183 3.1 0.973 Contact Map
3ec1A 1 0.4183 2.9 0.973 Contact Map
2dkyA 1 0.2484 2.7 0.974 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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