UXAC - ECOLI - GREMLIN Contacts

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UXAC - Uronate isomerase

UniProt:	P0A8G3	Sequences: MTPFMTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPQQIAEDYRFKNLYDIWLKGDHYKWRAMRTNGVAERLCTGDASDREKFDAWAATVPHTIGNPLYHWTHLELRRPFGITGKLLSPSTADEIWNECNELLAQDNFSARGIMQQMNVKMVGTTDDPIDSLEHHAEIAKDGSFTIKVLPSWRPDKAFNIEQATFNDYMAKLGEVSDTDIRRFADLQTALTKRLDHFAAHGCKVSDHALDVVMFAEANEAELDSILARRLAGETLSEHEVAQFKTAVLVFLGAEYARRGWVQQYHIGALRNNNLRQFKLLGPDVGFDSINDRPMAEELSKLLSKQNEENLLPKTILYCLNPRDNEVLGTMIGNFQGEGMPGKMQFGSGWWFNDQKDGMERQMTQLAQLGLLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGRWVEAGEAPADINLLGEMVKNICFNNARDYFAIELN	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12737
Length:	470 (446)
Sequences:	1198 (854)
Seq/√Len:	40.4

ECOLI - UXAC
BACSU - UXAC

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
90_A	121_P	4.008	1.00
260_R	271_E	3.475	1.00
82_R	125_D	3.280	1.00
39_Q	43_E	3.113	1.00
158_D	182_P	2.948	1.00
48_K	52_D	2.942	1.00
230_A	235_K	2.863	1.00
125_D	129_N	2.858	1.00
44_D	141_S	2.846	1.00
89_A	119_L	2.844	1.00
433_I	453_V	2.841	1.00
214_R	217_D	2.831	1.00
87_A	90_A	2.804	1.00
49_N	81_D	2.744	1.00
116_G	123_T	2.736	1.00
253_E	274_Q	2.689	1.00
116_G	126_E	2.666	1.00
455_N	459_N	2.641	1.00
86_D	125_D	2.634	1.00
152_K	462_R	2.608	1.00
68_N	405_R	2.517	1.00
387_K	441_E	2.503	1.00
110_R	423_E	2.468	1.00
306_L	335_S	2.455	1.00
250_N	253_E	2.419	1.00
114_I	127_I	2.379	1.00
198_N	262_L	2.317	1.00
391_E	431_Q	2.302	1.00
130_E	134_L	2.279	1.00
82_R	86_D	2.272	1.00
143_R	173_D	2.263	1.00
168_A	232_H	2.195	0.99
34_C	419_Y	2.194	0.99
168_A	172_K	2.193	0.99
216_A	251_E	2.186	0.99
230_A	292_W	2.182	0.99
202_A	262_L	2.142	0.99
15_F	438_E	2.129	0.99
267_L	272_V	2.098	0.99
109_R	115_T	2.091	0.99
170_I	180_V	2.079	0.99
362_M	365_N	2.066	0.99
74_L	87_A	2.063	0.99
166_H	169_E	2.060	0.99
147_Q	177_T	2.045	0.99
348_L	359_L	2.023	0.99
18_R	444_A	1.997	0.99
12_D	431_Q	1.985	0.99
228_H	232_H	1.983	0.99
114_I	130_E	1.966	0.99
320_S	365_N	1.938	0.99
73_R	78_D	1.933	0.99
122_S	447_N	1.914	0.99
44_D	143_R	1.906	0.99
42_A	169_E	1.890	0.98
18_R	22_D	1.877	0.98
227_D	290_R	1.869	0.98
155_G	236_V	1.826	0.98
347_I	407_V	1.817	0.98
88_W	100_L	1.791	0.98
155_G	183_S	1.776	0.98
432_M	436_W	1.770	0.98
111_P	149_M	1.769	0.98
120_S	123_T	1.751	0.97
14_E	17_R	1.747	0.97
226_L	287_Y	1.741	0.97
236_V	293_V	1.711	0.97
27_Q	459_N	1.710	0.97
372_P	405_R	1.700	0.97
30_F	467_I	1.694	0.97
285_A	340_E	1.665	0.96
286_E	289_R	1.660	0.96
92_V	104_T	1.658	0.96
331_S	362_M	1.658	0.96
205_G	208_S	1.641	0.96
201_M	218_L	1.641	0.96
255_D	258_L	1.627	0.96
94_H	455_N	1.626	0.96
454_K	459_N	1.618	0.96
270_H	274_Q	1.615	0.96
52_D	81_D	1.613	0.96
223_T	289_R	1.598	0.96
184_W	222_L	1.594	0.95
360_G	400_L	1.591	0.95
213_R	217_D	1.590	0.95
92_V	95_T	1.588	0.95
268_S	271_E	1.581	0.95
183_S	236_V	1.575	0.95
205_G	211_D	1.566	0.95
95_T	402_L	1.561	0.95
155_G	181_L	1.554	0.95
307_R	338_N	1.554	0.95
30_F	152_K	1.554	0.95
129_N	133_E	1.548	0.95
216_A	255_D	1.547	0.95
394_M	432_M	1.532	0.94
193_E	276_K	1.523	0.94
219_Q	282_F	1.520	0.94
223_T	286_E	1.514	0.94
46_R	138_D	1.513	0.94
39_Q	166_H	1.504	0.94
210_T	224_K	1.504	0.94
308_Q	318_F	1.482	0.93
153_M	181_L	1.459	0.93
357_E	392_R	1.458	0.93
97_G	436_W	1.453	0.93
146_M	178_I	1.445	0.92
67_T	400_L	1.435	0.92
13_T	435_R	1.433	0.92
133_E	137_Q	1.432	0.92
226_L	286_E	1.431	0.92
299_G	350_C	1.424	0.92
82_R	129_N	1.418	0.92
161_I	207_V	1.401	0.91
26_D	454_K	1.399	0.91
146_M	149_M	1.391	0.91
40_Q	45_Y	1.389	0.91
285_A	342_L	1.387	0.91
161_I	208_S	1.386	0.91
254_L	278_A	1.385	0.91
44_D	138_D	1.380	0.91
215_F	278_A	1.378	0.90
330_L	334_L	1.376	0.90
170_I	173_D	1.374	0.90
86_D	121_P	1.373	0.90
300_A	351_L	1.371	0.90
450_G	454_K	1.360	0.90
80_S	83_E	1.354	0.90
257_I	274_Q	1.354	0.90
123_T	126_E	1.352	0.90
281_V	336_K	1.345	0.89
218_L	275_F	1.339	0.89
27_Q	454_K	1.336	0.89
146_M	176_F	1.336	0.89
46_R	142_A	1.335	0.89
186_P	239_H	1.333	0.89
173_D	176_F	1.331	0.89
34_C	146_M	1.323	0.89
282_F	286_E	1.320	0.88
204_L	222_L	1.309	0.88
44_D	147_Q	1.297	0.88
279_V	283_L	1.295	0.87
193_E	272_V	1.293	0.87
295_Q	349_Y	1.291	0.87
68_N	91_T	1.289	0.87
146_M	154_V	1.288	0.87
43_E	169_E	1.284	0.87
406_F	425_F	1.281	0.87
27_Q	152_K	1.278	0.87
356_N	377_F	1.277	0.87
335_S	339_E	1.275	0.87
286_E	290_R	1.267	0.86
34_C	154_V	1.266	0.86
433_I	437_V	1.266	0.86
152_K	458_F	1.261	0.86
334_L	375_M	1.261	0.86
226_L	290_R	1.260	0.86
450_G	455_N	1.254	0.86
140_F	145_I	1.247	0.85
146_M	419_Y	1.244	0.85
116_G	127_I	1.243	0.85
348_L	375_M	1.240	0.85
104_T	119_L	1.229	0.85
42_A	170_I	1.223	0.84
435_R	439_A	1.221	0.84
88_W	91_T	1.215	0.84
46_R	141_S	1.213	0.84
458_F	462_R	1.211	0.84
215_F	279_V	1.208	0.83
73_R	79_A	1.205	0.83
386_Q	399_Q	1.202	0.83
70_V	91_T	1.197	0.83
50_L	132_N	1.196	0.83
283_L	287_Y	1.192	0.83
92_V	105_H	1.190	0.83
20_Y	25_K	1.188	0.82
327_A	358_V	1.188	0.82
212_I	217_D	1.187	0.82
116_G	130_E	1.185	0.82
214_R	255_D	1.180	0.82
260_R	267_L	1.164	0.81
306_L	339_E	1.164	0.81
304_N	331_S	1.163	0.81
388_D	399_Q	1.162	0.81
249_A	254_L	1.162	0.81
134_L	137_Q	1.160	0.81
188_K	315_D	1.159	0.81
67_T	363_I	1.154	0.81
43_E	166_H	1.153	0.81
331_S	365_N	1.147	0.80
303_N	309_F	1.146	0.80
255_D	259_A	1.143	0.80
96_I	452_M	1.140	0.80
387_K	428_I	1.139	0.80
215_F	254_L	1.133	0.79
15_F	437_V	1.132	0.79
126_E	130_E	1.125	0.79
196_T	199_D	1.124	0.79
380_G	383_F	1.124	0.79
228_H	231_A	1.121	0.79
282_F	285_A	1.116	0.78
106_L	110_R	1.114	0.78
134_L	140_F	1.107	0.78
114_I	131_C	1.103	0.77
108_L	127_I	1.098	0.77
54_W	107_E	1.090	0.77
391_E	435_R	1.085	0.76
303_N	315_D	1.085	0.76
155_G	293_V	1.084	0.76
18_R	446_I	1.082	0.76
140_F	148_Q	1.078	0.76
192_I	261_R	1.078	0.76
12_D	435_R	1.074	0.76
332_K	335_S	1.071	0.75
288_A	342_L	1.070	0.75
171_A	232_H	1.065	0.75
132_N	136_A	1.065	0.75
64_A	100_L	1.062	0.75
216_A	220_T	1.062	0.75
71_A	74_L	1.060	0.75
82_R	124_A	1.049	0.74
12_D	439_A	1.044	0.73
387_K	391_E	1.040	0.73
298_I	326_M	1.038	0.73
394_M	403_L	1.034	0.73
93_P	121_P	1.033	0.73
168_A	228_H	1.026	0.72
41_I	180_V	1.026	0.72
153_M	467_I	1.022	0.72
44_D	144_G	1.022	0.72
387_K	439_A	1.022	0.72
51_Y	81_D	1.021	0.72
227_D	231_A	1.021	0.72
170_I	176_F	1.020	0.72
210_T	220_T	1.012	0.71
247_A	270_H	1.010	0.71
247_A	274_Q	1.010	0.71
15_F	434_G	1.005	0.71
452_M	455_N	0.998	0.70
184_W	204_L	0.993	0.70
198_N	202_A	0.988	0.69
68_N	402_L	0.984	0.69
119_L	123_T	0.983	0.69
13_T	431_Q	0.980	0.69
403_L	407_V	0.972	0.68
50_L	131_C	0.971	0.68
106_L	423_E	0.969	0.68
199_D	202_A	0.964	0.67
76_T	84_K	0.963	0.67
27_Q	30_F	0.960	0.67
161_I	203_K	0.959	0.67
139_N	148_Q	0.958	0.67
217_D	220_T	0.949	0.66
36_L	154_V	0.948	0.66
176_F	180_V	0.947	0.66
181_L	236_V	0.946	0.66
285_A	337_Q	0.945	0.66
108_L	114_I	0.943	0.66
350_C	377_F	0.940	0.65
92_V	404_S	0.935	0.65
318_F	371_M	0.934	0.65
189_A	222_L	0.929	0.64
248_E	336_K	0.926	0.64
219_Q	286_E	0.924	0.64
209_D	224_K	0.922	0.64
88_W	92_V	0.920	0.64
261_R	267_L	0.916	0.63
304_N	320_S	0.915	0.63
442_A	448_L	0.910	0.63
260_R	265_E	0.907	0.63
45_Y	56_K	0.905	0.62
337_Q	342_L	0.903	0.62
52_D	56_K	0.902	0.62
223_T	285_A	0.902	0.62
24_A	453_V	0.897	0.62
184_W	226_L	0.885	0.61
247_A	273_A	0.885	0.61
130_E	133_E	0.885	0.61
141_S	144_G	0.883	0.60
79_A	84_K	0.882	0.60
331_S	335_S	0.881	0.60
320_S	362_M	0.880	0.60
390_M	394_M	0.879	0.60
367_Q	375_M	0.876	0.60
208_S	224_K	0.876	0.60
113_G	134_L	0.875	0.60
51_Y	84_K	0.873	0.60
223_T	227_D	0.871	0.59
308_Q	311_L	0.870	0.59
391_E	395_T	0.867	0.59
197_F	218_L	0.866	0.59
24_A	457_C	0.864	0.59
296_Y	346_T	0.863	0.59
246_F	277_T	0.863	0.59
88_W	95_T	0.861	0.58
403_L	433_I	0.860	0.58
64_A	95_T	0.859	0.58
403_L	429_L	0.859	0.58
100_L	104_T	0.858	0.58
280_L	296_Y	0.854	0.58
118_L	443_P	0.851	0.58
188_K	314_P	0.850	0.57
118_L	442_A	0.850	0.57
397_L	401_G	0.847	0.57
202_A	206_E	0.844	0.57
15_F	444_A	0.843	0.57
66_R	371_M	0.841	0.57
190_F	279_V	0.837	0.56
183_S	293_V	0.837	0.56
202_A	211_D	0.836	0.56
30_F	462_R	0.836	0.56
257_I	267_L	0.835	0.56
429_L	456_I	0.834	0.56
137_Q	140_F	0.834	0.56
249_A	278_A	0.834	0.56
275_F	279_V	0.827	0.55
68_N	372_P	0.825	0.55
89_A	127_I	0.823	0.55
198_N	261_R	0.821	0.55
388_D	395_T	0.815	0.54
104_T	123_T	0.815	0.54
34_C	149_M	0.814	0.54
66_R	305_N	0.814	0.54
205_G	262_L	0.813	0.54
51_Y	55_L	0.811	0.54
155_G	467_I	0.811	0.54
299_G	365_N	0.810	0.54
41_I	170_I	0.808	0.54
143_R	176_F	0.808	0.54
345_K	466_A	0.808	0.54
145_I	416_F	0.807	0.54
348_L	363_I	0.802	0.53
357_E	396_Q	0.801	0.53
242_D	328_E	0.801	0.53
89_A	123_T	0.800	0.53
110_R	420_T	0.800	0.53
212_I	258_L	0.800	0.53
160_P	188_K	0.798	0.53
49_N	52_D	0.798	0.53
203_K	206_E	0.797	0.53
165_E	169_E	0.797	0.53
149_M	419_Y	0.796	0.53
119_L	127_I	0.793	0.52
78_D	84_K	0.793	0.52
461_A	465_F	0.785	0.52
24_A	430_C	0.783	0.51
333_L	337_Q	0.783	0.51
215_F	258_L	0.781	0.51
190_F	283_L	0.779	0.51
55_L	84_K	0.778	0.51
398_A	436_W	0.778	0.51
201_M	262_L	0.777	0.51
101_Y	105_H	0.776	0.51
96_I	433_I	0.776	0.51
363_I	375_M	0.776	0.51
245_M	277_T	0.770	0.50
243_V	273_A	0.770	0.50
82_R	121_P	0.770	0.50
281_V	285_A	0.767	0.50
325_P	328_E	0.766	0.50
259_A	262_L	0.764	0.50
244_V	333_L	0.763	0.49
144_G	148_Q	0.763	0.49
392_R	395_T	0.762	0.49
304_N	365_N	0.762	0.49
308_Q	316_V	0.760	0.49
392_R	396_Q	0.759	0.49
347_I	464_Y	0.757	0.49
169_E	172_K	0.755	0.49
96_I	437_V	0.753	0.49
457_C	461_A	0.752	0.48
334_L	348_L	0.751	0.48
88_W	104_T	0.747	0.48
149_M	420_T	0.742	0.48
288_A	340_E	0.741	0.47
451_E	455_N	0.740	0.47
173_D	178_I	0.740	0.47
223_T	290_R	0.739	0.47
95_T	386_Q	0.739	0.47
159_D	188_K	0.737	0.47
138_D	141_S	0.737	0.47
251_E	255_D	0.731	0.47
66_R	318_F	0.727	0.46
256_S	260_R	0.726	0.46
37_P	40_Q	0.725	0.46
45_Y	52_D	0.725	0.46
13_T	16_A	0.724	0.46
327_A	362_M	0.723	0.46
359_L	384_N	0.721	0.46
226_L	230_A	0.720	0.46
97_G	395_T	0.720	0.46
183_S	380_G	0.715	0.45
211_D	217_D	0.713	0.45
67_T	360_G	0.711	0.45
144_G	147_Q	0.710	0.45
153_M	183_S	0.710	0.45
171_A	174_G	0.709	0.45
123_T	130_E	0.709	0.45
96_I	442_A	0.708	0.44
227_D	230_A	0.708	0.44
301_L	332_K	0.706	0.44
254_L	258_L	0.705	0.44
388_D	392_R	0.701	0.44
226_L	283_L	0.700	0.44
446_I	450_G	0.700	0.44
61_K	100_L	0.700	0.44
306_L	310_K	0.699	0.44
384_N	398_A	0.693	0.43
379_S	410_L	0.690	0.43
325_P	329_E	0.689	0.43
145_I	420_T	0.689	0.43
49_N	132_N	0.688	0.43
118_L	448_L	0.687	0.43
459_N	463_D	0.685	0.42
379_S	407_V	0.684	0.42
305_N	371_M	0.684	0.42
223_T	282_F	0.684	0.42
30_F	458_F	0.684	0.42
305_N	318_F	0.681	0.42
237_S	292_W	0.681	0.42
97_G	294_Q	0.681	0.42
301_L	327_A	0.679	0.42
153_M	179_K	0.679	0.42
391_E	428_I	0.678	0.42
301_L	328_E	0.676	0.42
79_A	83_E	0.675	0.41
259_A	263_A	0.675	0.41
350_C	365_N	0.674	0.41
377_F	380_G	0.674	0.41
305_N	338_N	0.673	0.41
250_N	274_Q	0.673	0.41
216_A	259_A	0.672	0.41
154_V	306_L	0.670	0.41
97_G	398_A	0.670	0.41
134_L	138_D	0.668	0.41
246_F	336_K	0.664	0.40
42_A	166_H	0.662	0.40
160_P	236_V	0.662	0.40
327_A	365_N	0.662	0.40
312_L	315_D	0.660	0.40
202_A	205_G	0.660	0.40
437_V	446_I	0.660	0.40
430_C	461_A	0.656	0.40
244_V	330_L	0.653	0.40
82_R	128_W	0.653	0.40
206_E	224_K	0.652	0.39
248_E	329_E	0.652	0.39
197_F	275_F	0.652	0.39
89_A	104_T	0.651	0.39
128_W	367_Q	0.649	0.39
59_H	157_T	0.646	0.39
305_N	339_E	0.645	0.39
246_F	249_A	0.644	0.39
220_T	224_K	0.643	0.39
110_R	149_M	0.642	0.39
309_F	314_P	0.641	0.38
349_Y	379_S	0.641	0.38
13_T	438_E	0.641	0.38
147_Q	178_I	0.640	0.38
158_D	162_D	0.640	0.38
25_K	169_E	0.639	0.38
433_I	452_M	0.636	0.38
331_S	355_D	0.636	0.38
50_L	56_K	0.635	0.38
218_L	279_V	0.634	0.38
27_Q	458_F	0.634	0.38
257_I	275_F	0.634	0.38
320_S	327_A	0.634	0.38
225_R	228_H	0.634	0.38
271_E	274_Q	0.633	0.38
86_D	124_A	0.633	0.38
218_L	283_L	0.633	0.38
357_E	386_Q	0.633	0.38
82_R	123_T	0.633	0.38
50_L	82_R	0.632	0.38
284_G	337_Q	0.631	0.38
20_Y	423_E	0.631	0.38
91_T	100_L	0.629	0.37
242_D	276_K	0.629	0.37
192_I	257_I	0.628	0.37
67_T	318_F	0.627	0.37
218_L	258_L	0.626	0.37
191_N	276_K	0.626	0.37
17_R	435_R	0.626	0.37
163_S	332_K	0.625	0.37
102_H	428_I	0.623	0.37
315_D	416_F	0.621	0.37
191_N	194_Q	0.621	0.37
291_G	466_A	0.617	0.36
437_V	442_A	0.616	0.36
86_D	90_A	0.614	0.36
135_L	144_G	0.614	0.36
425_F	429_L	0.613	0.36
14_E	18_R	0.611	0.36
201_M	261_R	0.610	0.36
247_A	277_T	0.608	0.36
122_S	126_E	0.607	0.36
64_A	67_T	0.607	0.36
19_L	24_A	0.607	0.36
254_L	274_Q	0.607	0.36
431_Q	439_A	0.606	0.35
83_E	165_E	0.606	0.35
89_A	116_G	0.605	0.35
125_D	131_C	0.605	0.35
51_Y	56_K	0.604	0.35
284_G	296_Y	0.604	0.35
215_F	282_F	0.603	0.35
249_A	274_Q	0.602	0.35
336_K	339_E	0.602	0.35
158_D	183_S	0.600	0.35
442_A	452_M	0.599	0.35
128_W	436_W	0.599	0.35
75_C	84_K	0.599	0.35
253_E	256_S	0.599	0.35
52_D	132_N	0.598	0.35
302_R	315_D	0.598	0.35
183_S	350_C	0.598	0.35
350_C	384_N	0.598	0.35
120_S	451_E	0.597	0.35
280_L	333_L	0.595	0.35
87_A	121_P	0.595	0.35
360_G	363_I	0.594	0.34
226_L	292_W	0.593	0.34
368_G	371_M	0.592	0.34
434_G	438_E	0.592	0.34
96_I	446_I	0.589	0.34
350_C	359_L	0.589	0.34
198_N	208_S	0.589	0.34
345_K	376_Q	0.589	0.34
394_M	398_A	0.588	0.34
251_E	282_F	0.587	0.34
197_F	201_M	0.587	0.34
244_V	334_L	0.587	0.34
194_Q	303_N	0.586	0.34
53_I	417_L	0.584	0.34
203_K	207_V	0.584	0.34
360_G	377_F	0.584	0.34
208_S	211_D	0.584	0.34
230_A	236_V	0.583	0.34
236_V	349_Y	0.583	0.34
284_G	333_L	0.582	0.33
118_L	445_D	0.582	0.33
312_L	316_V	0.582	0.33
198_N	201_M	0.579	0.33
32_Y	464_Y	0.579	0.33
20_Y	109_R	0.578	0.33
201_M	258_L	0.576	0.33
219_Q	223_T	0.575	0.33
168_A	171_A	0.572	0.33
72_E	312_L	0.572	0.33
189_A	200_Y	0.571	0.33
191_N	240_A	0.571	0.33
205_G	217_D	0.570	0.32
21_H	24_A	0.570	0.32
386_Q	404_S	0.569	0.32
236_V	467_I	0.568	0.32
380_G	386_Q	0.567	0.32
248_E	332_K	0.567	0.32
162_D	203_K	0.565	0.32
36_L	323_D	0.565	0.32
127_I	130_E	0.564	0.32
377_F	397_L	0.563	0.32
19_L	453_V	0.562	0.32
285_A	336_K	0.561	0.32
219_Q	279_V	0.559	0.32
72_E	311_L	0.559	0.32
245_M	273_A	0.558	0.32
226_L	372_P	0.557	0.31
197_F	258_L	0.557	0.31
86_D	129_N	0.556	0.31
253_E	257_I	0.554	0.31
326_M	358_V	0.554	0.31
349_Y	410_L	0.554	0.31
199_D	261_R	0.554	0.31
364_G	400_L	0.554	0.31
392_R	399_Q	0.554	0.31
284_G	342_L	0.552	0.31
284_G	294_Q	0.552	0.31
43_E	165_E	0.552	0.31
146_M	457_C	0.551	0.31
26_D	150_N	0.551	0.31
159_D	200_Y	0.550	0.31
326_M	329_E	0.550	0.31
149_M	154_V	0.549	0.31
294_Q	436_W	0.549	0.31
288_A	341_N	0.549	0.31
267_L	271_E	0.548	0.31
318_F	338_N	0.545	0.30
192_I	275_F	0.544	0.30
76_T	79_A	0.543	0.30
390_M	428_I	0.543	0.30
330_L	348_L	0.542	0.30
96_I	448_L	0.542	0.30
254_L	257_I	0.542	0.30
290_R	399_Q	0.541	0.30
360_G	365_N	0.541	0.30
394_M	425_F	0.541	0.30
171_A	231_A	0.540	0.30
380_G	393_Q	0.540	0.30
296_Y	329_E	0.539	0.30
355_D	362_M	0.539	0.30
15_F	450_G	0.539	0.30
357_E	400_L	0.539	0.30
161_I	218_L	0.538	0.30
104_T	108_L	0.537	0.30
198_N	264_G	0.536	0.30
264_G	335_S	0.535	0.30
428_I	431_Q	0.535	0.30
22_D	446_I	0.534	0.30
395_T	398_A	0.534	0.30
21_H	25_K	0.533	0.30
134_L	150_N	0.533	0.30
289_R	342_L	0.533	0.30
91_T	405_R	0.533	0.30
205_G	212_I	0.533	0.30
226_L	261_R	0.533	0.30
30_F	188_K	0.532	0.29
63_R	422_H	0.531	0.29
49_N	128_W	0.530	0.29
188_K	196_T	0.528	0.29
210_T	217_D	0.528	0.29
248_E	278_A	0.527	0.29
84_K	345_K	0.524	0.29
74_L	80_S	0.524	0.29
269_E	273_A	0.523	0.29
13_T	17_R	0.523	0.29
463_D	466_A	0.523	0.29
152_K	459_N	0.523	0.29
139_N	144_G	0.522	0.29
87_A	300_A	0.522	0.29
393_Q	397_L	0.522	0.29
163_S	166_H	0.522	0.29
62_W	72_E	0.522	0.29
79_A	87_A	0.521	0.29
301_L	331_S	0.519	0.28
193_E	267_L	0.518	0.28
155_G	432_M	0.518	0.28
146_M	416_F	0.517	0.28
159_D	207_V	0.517	0.28
219_Q	291_G	0.516	0.28
362_M	377_F	0.515	0.28
396_Q	428_I	0.515	0.28
203_K	444_A	0.514	0.28
53_I	145_I	0.514	0.28
78_D	211_D	0.513	0.28
104_T	393_Q	0.512	0.28
384_N	436_W	0.511	0.28
113_G	116_G	0.511	0.28
121_P	125_D	0.510	0.28
153_M	466_A	0.510	0.28
40_Q	56_K	0.510	0.28
206_E	407_V	0.510	0.28
95_T	404_S	0.509	0.28
240_A	314_P	0.509	0.28
307_R	311_L	0.509	0.28
200_Y	205_G	0.508	0.28
86_D	120_S	0.508	0.28
169_E	260_R	0.507	0.28
282_F	290_R	0.507	0.28
140_F	176_F	0.507	0.28
47_F	53_I	0.507	0.28
38_P	166_H	0.506	0.28
459_N	462_R	0.504	0.27
431_Q	435_R	0.504	0.27
183_S	226_L	0.504	0.27
350_C	362_M	0.502	0.27
380_G	461_A	0.501	0.27
120_S	445_D	0.501	0.27
265_E	271_E	0.500	0.27

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3iacA	3	0.9936	100	0.14	Contact Map
2q01A	3	0.9702	100	0.228	Contact Map
1j5sA	3	0.9532	100	0.25	Contact Map
4i6vA	3	0.8957	100	0.382	Contact Map
2qeeA	5	0.8553	100	0.41	Contact Map
2qpxA	3	0.7638	100	0.645	Contact Map
3irsA	3	0.5617	97.3	0.964	Contact Map
3nurA	2	0.5894	95.8	0.969	Contact Map
4mupA	1	0.5638	95.7	0.97	Contact Map
3gg7A	1	0.5021	95.6	0.97	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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