UVRC - ECOLI - GREMLIN Contacts

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UVRC - UvrABC system protein C

UniProt:	P0A8G0	Sequences: MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLLEHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYRNRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVTEKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLDFNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEVKRMECFDISHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDDSKIPDVILIDGGKGQLAQAKNVFAELDVSWDKNHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLETIEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11063
Length:	610 (587)
Sequences:	3227 (1922)
Seq/√Len:	79.3

ECOLI - UVRC
BACSU - UVRC
HALSA - UVRC

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
111_T	185_E	4.556	1.00
16_S	38_D	4.451	1.00
602_E	606_W	4.304	1.00
14_V	43_L	4.006	1.00
222_E	225_E	3.950	1.00
421_L	424_E	3.829	1.00
213_R	229_I	3.449	1.00
429_N	548_K	3.398	1.00
25_D	29_T	3.383	1.00
184_S	187_E	3.383	1.00
605_F	609_K	3.345	1.00
582_L	590_I	3.315	1.00
443_N	477_N	3.143	1.00
559_E	569_R	3.139	1.00
60_V	63_I	3.029	1.00
596_I	604_I	3.003	1.00
416_D	421_L	2.998	1.00
30_V	88_Y	2.853	1.00
127_E	196_R	2.782	1.00
407_Q	552_V	2.750	1.00
211_I	237_R	2.718	1.00
496_V	530_I	2.544	1.00
469_K	473_A	2.532	1.00
28_G	65_Q	2.525	1.00
429_N	544_G	2.519	1.00
207_L	233_I	2.436	1.00
393_K	417_A	2.425	1.00
472_L	495_G	2.417	1.00
398_F	450_Y	2.413	1.00
259_F	292_L	2.369	1.00
589_E	592_K	2.304	1.00
10_F	65_Q	2.302	1.00
16_S	40_K	2.268	1.00
447_R	481_E	2.263	1.00
210_L	233_I	2.260	1.00
216_T	220_N	2.229	1.00
591_A	598_Q	2.228	1.00
352_A	356_K	2.224	1.00
598_Q	602_E	2.188	1.00
106_F	126_G	2.170	1.00
464_L	494_L	2.159	1.00
26_A	64_Q	2.101	1.00
581_G	584_N	2.080	1.00
227_A	231_D	2.072	1.00
211_I	215_E	2.051	1.00
183_V	187_E	2.050	1.00
112_H	159_Y	2.048	1.00
587_V	591_A	2.030	1.00
217_A	229_I	1.945	1.00
439_Y	470_G	1.945	1.00
213_R	225_E	1.943	1.00
586_S	589_E	1.935	1.00
117_M	139_R	1.929	1.00
383_L	526_A	1.912	1.00
580_Q	584_N	1.910	1.00
587_V	602_E	1.892	1.00
215_E	219_Q	1.883	1.00
107_L	115_L	1.883	1.00
544_G	548_K	1.880	1.00
397_C	533_I	1.878	1.00
197_L	202_K	1.869	1.00
215_E	218_S	1.869	1.00
107_L	196_R	1.862	1.00
207_L	237_R	1.845	1.00
397_C	413_V	1.842	1.00
473_A	476_K	1.837	1.00
555_T	560_T	1.837	1.00
384_A	392_V	1.833	1.00
56_T	59_L	1.830	1.00
427_R	544_G	1.826	1.00
408_T	441_A	1.815	1.00
450_Y	463_I	1.809	1.00
165_P	179_V	1.782	1.00
72_H	244_F	1.781	1.00
31_I	91_R	1.780	1.00
179_V	182_L	1.774	1.00
476_K	493_L	1.772	1.00
24_Y	65_Q	1.772	1.00
212_S	216_T	1.769	1.00
256_G	320_D	1.768	1.00
31_I	55_K	1.760	1.00
187_E	190_Q	1.751	1.00
446_L	478_V	1.747	1.00
562_E	603_K	1.738	1.00
443_N	481_E	1.728	1.00
402_H	436_G	1.724	1.00
381_T	384_A	1.723	1.00
30_V	33_V	1.715	1.00
398_F	446_L	1.711	1.00
439_Y	474_Q	1.705	1.00
225_E	229_I	1.698	1.00
297_E	325_D	1.672	1.00
256_G	359_R	1.668	1.00
185_E	189_A	1.649	1.00
452_K	456_D	1.638	1.00
320_D	359_R	1.632	1.00
497_A	510_F	1.628	1.00
564_V	604_I	1.627	1.00
411_S	540_H	1.624	1.00
331_D	335_E	1.618	1.00
31_I	56_T	1.616	1.00
564_V	600_L	1.611	1.00
576_M	593_V	1.603	1.00
225_E	228_R	1.602	1.00
496_V	509_L	1.599	1.00
189_A	193_E	1.595	1.00
398_F	412_C	1.588	1.00
476_K	480_A	1.582	1.00
169_Y	176_G	1.574	1.00
397_C	537_S	1.572	1.00
478_V	482_L	1.570	1.00
391_E	461_D	1.569	1.00
319_L	343_V	1.568	1.00
38_D	41_K	1.567	1.00
16_S	41_K	1.566	1.00
597_S	600_L	1.557	0.99
326_K	330_A	1.553	0.99
17_Q	70_V	1.538	0.99
396_E	449_R	1.524	0.99
451_G	455_D	1.517	0.99
45_S	48_R	1.516	0.99
400_I	410_A	1.512	0.99
59_L	63_I	1.504	0.99
575_Y	593_V	1.503	0.99
258_A	363_A	1.500	0.99
209_Q	213_R	1.498	0.99
403_T	545_H	1.498	0.99
363_A	367_T	1.494	0.99
176_G	182_L	1.487	0.99
464_L	496_V	1.485	0.99
568_R	600_L	1.484	0.99
415_F	420_P	1.480	0.99
25_D	62_Q	1.477	0.99
509_L	530_I	1.470	0.99
70_V	364_T	1.469	0.99
484_V	491_P	1.464	0.99
463_I	479_F	1.464	0.99
109_G	126_G	1.459	0.99
599_G	603_K	1.456	0.99
24_Y	67_D	1.449	0.99
410_A	441_A	1.448	0.99
472_L	510_F	1.448	0.99
213_R	216_T	1.445	0.99
23_M	63_I	1.445	0.99
536_E	539_D	1.445	0.99
531_Q	535_D	1.439	0.99
600_L	604_I	1.435	0.99
394_R	424_E	1.433	0.99
270_F	303_F	1.432	0.99
414_V	424_E	1.429	0.99
127_E	200_S	1.429	0.99
476_K	512_E	1.426	0.99
506_L	534_R	1.409	0.99
443_N	478_V	1.408	0.99
474_Q	478_V	1.407	0.99
579_L	582_L	1.406	0.99
255_I	299_F	1.406	0.99
217_A	222_E	1.400	0.99
255_I	300_V	1.394	0.99
175_L	183_V	1.389	0.99
600_L	603_K	1.386	0.99
255_I	268_V	1.384	0.99
411_S	537_S	1.380	0.99
55_K	59_L	1.380	0.99
315_G	339_R	1.378	0.99
575_Y	592_K	1.375	0.99
394_R	416_D	1.375	0.99
596_I	600_L	1.366	0.99
411_S	541_A	1.359	0.99
54_R	57_E	1.346	0.98
545_H	549_R	1.343	0.98
210_L	229_I	1.338	0.98
410_A	445_V	1.327	0.98
402_H	430_I	1.324	0.98
115_L	195_V	1.324	0.98
14_V	66_I	1.323	0.98
507_E	534_R	1.322	0.98
25_D	31_I	1.315	0.98
48_R	51_L	1.311	0.98
150_P	195_V	1.307	0.98
108_S	116_A	1.306	0.98
431_T	444_Q	1.303	0.98
510_F	517_G	1.303	0.98
571_M	593_V	1.301	0.98
566_P	570_Q	1.294	0.98
567_K	570_Q	1.287	0.98
402_H	433_I	1.285	0.98
443_N	447_R	1.282	0.98
190_Q	193_E	1.276	0.98
153_Q	168_Q	1.275	0.98
269_L	279_S	1.273	0.98
318_L	355_L	1.270	0.98
397_C	464_L	1.269	0.98
382_A	526_A	1.264	0.98
497_A	508_T	1.259	0.98
527_L	531_Q	1.259	0.98
292_L	321_F	1.258	0.98
53_S	56_T	1.256	0.98
542_I	546_R	1.255	0.98
446_L	475_A	1.255	0.98
318_L	344_Q	1.251	0.98
447_R	478_V	1.249	0.98
319_L	345_T	1.246	0.97
465_I	475_A	1.242	0.97
150_P	191_Q	1.235	0.97
348_R	351_R	1.233	0.97
291_E	294_E	1.231	0.97
316_E	351_R	1.225	0.97
381_T	385_S	1.220	0.97
82_H	101_S	1.219	0.97
402_H	408_T	1.218	0.97
401_S	542_I	1.211	0.97
8_K	12_K	1.211	0.97
379_R	526_A	1.208	0.97
382_A	524_S	1.203	0.97
499_G	534_R	1.203	0.97
432_G	444_Q	1.202	0.97
41_K	49_S	1.195	0.97
234_Q	237_R	1.195	0.97
293_S	321_F	1.193	0.97
350_D	353_R	1.190	0.97
147_K	173_R	1.188	0.97
403_T	550_A	1.185	0.97
484_V	490_H	1.185	0.97
10_F	13_T	1.182	0.97
265_C	283_F	1.176	0.96
296_V	320_D	1.176	0.96
561_I	604_I	1.176	0.96
601_A	604_I	1.174	0.96
316_E	342_N	1.172	0.96
41_K	44_S	1.169	0.96
410_A	430_I	1.167	0.96
208_T	211_I	1.167	0.96
110_D	156_N	1.158	0.96
430_I	441_A	1.155	0.96
117_M	138_V	1.153	0.96
194_Y	209_Q	1.147	0.96
437_D	440_A	1.147	0.96
604_I	608_L	1.145	0.96
207_L	211_I	1.135	0.96
24_Y	28_G	1.135	0.96
494_L	509_L	1.132	0.96
587_V	605_F	1.132	0.96
227_A	230_R	1.131	0.96
567_K	571_M	1.131	0.96
437_D	443_N	1.130	0.96
442_M	446_L	1.127	0.95
527_L	534_R	1.126	0.95
316_E	344_Q	1.125	0.95
480_A	485_S	1.125	0.95
359_R	363_A	1.123	0.95
464_L	530_I	1.122	0.95
526_A	529_V	1.121	0.95
150_P	175_L	1.120	0.95
394_R	414_V	1.119	0.95
395_M	533_I	1.114	0.95
118_H	126_G	1.114	0.95
402_H	435_P	1.114	0.95
400_I	411_S	1.112	0.95
122_K	126_G	1.110	0.95
267_H	279_S	1.106	0.95
386_V	520_L	1.105	0.95
254_V	271_I	1.103	0.95
409_V	548_K	1.102	0.95
304_Y	314_P	1.102	0.95
168_Q	173_R	1.090	0.95
427_R	547_K	1.090	0.95
605_F	608_L	1.086	0.94
129_F	196_R	1.086	0.94
151_I	195_V	1.085	0.94
7_A	11_L	1.083	0.94
398_F	463_I	1.076	0.94
112_H	185_E	1.071	0.94
52_A	60_V	1.068	0.94
356_K	360_T	1.063	0.94
112_H	181_G	1.063	0.94
300_V	317_I	1.062	0.94
499_G	508_T	1.059	0.94
531_Q	534_R	1.058	0.94
587_V	601_A	1.055	0.94
109_G	125_K	1.053	0.93
166_C	174_C	1.050	0.93
537_S	540_H	1.049	0.93
24_Y	30_V	1.049	0.93
346_K	351_R	1.042	0.93
547_K	551_K	1.041	0.93
169_Y	182_L	1.040	0.93
183_V	191_Q	1.036	0.93
356_K	359_R	1.031	0.93
166_C	178_C	1.029	0.93
159_Y	162_R	1.028	0.93
62_Q	92_Y	1.026	0.93
217_A	225_E	1.023	0.92
403_T	407_Q	1.019	0.92
497_A	534_R	1.016	0.92
443_N	474_Q	1.016	0.92
446_L	474_Q	1.011	0.92
144_L	148_I	1.011	0.92
412_C	428_Y	1.010	0.92
406_E	553_K	1.009	0.92
55_K	94_V	1.006	0.92
215_E	221_L	1.003	0.92
534_R	537_S	0.999	0.92
11_L	14_V	0.995	0.91
508_T	517_G	0.995	0.91
175_L	191_Q	0.993	0.91
105_I	115_L	0.992	0.91
499_G	506_L	0.992	0.91
379_R	529_V	0.990	0.91
557_S	607_S	0.989	0.91
479_F	484_V	0.986	0.91
269_L	358_A	0.984	0.91
258_A	366_L	0.983	0.91
395_M	462_V	0.980	0.91
479_F	493_L	0.979	0.91
268_V	303_F	0.978	0.91
194_Y	205_Q	0.975	0.91
420_P	532_H	0.974	0.91
402_H	441_A	0.973	0.90
428_Y	452_K	0.972	0.90
58_A	62_Q	0.971	0.90
507_E	512_E	0.968	0.90
568_R	571_M	0.965	0.90
174_C	178_C	0.964	0.90
557_S	560_T	0.959	0.90
353_R	356_K	0.958	0.90
118_H	121_A	0.958	0.90
400_I	442_M	0.955	0.90
204_D	208_T	0.955	0.90
106_F	124_A	0.954	0.90
74_E	78_L	0.951	0.89
330_A	343_V	0.951	0.89
398_F	410_A	0.950	0.89
425_Y	536_E	0.950	0.89
568_R	596_I	0.949	0.89
23_M	66_I	0.947	0.89
337_A	341_I	0.946	0.89
581_G	589_E	0.946	0.89
322_N	326_K	0.944	0.89
454_I	482_L	0.942	0.89
587_V	598_Q	0.939	0.89
112_H	175_L	0.936	0.89
301_G	329_L	0.936	0.89
450_Y	482_L	0.935	0.89
83_N	246_S	0.932	0.88
568_R	597_S	0.932	0.88
17_Q	360_T	0.932	0.88
76_E	243_Q	0.931	0.88
248_T	252_L	0.931	0.88
404_M	545_H	0.930	0.88
364_T	368_S	0.929	0.88
259_F	264_A	0.928	0.88
398_F	445_V	0.926	0.88
437_D	470_G	0.925	0.88
544_G	547_K	0.923	0.88
146_Q	153_Q	0.923	0.88
301_G	332_S	0.922	0.88
67_D	279_S	0.911	0.87
572_L	582_L	0.910	0.87
360_T	363_A	0.910	0.87
212_S	215_E	0.908	0.87
256_G	362_A	0.908	0.87
22_R	67_D	0.906	0.87
507_E	517_G	0.905	0.87
193_E	196_R	0.905	0.87
197_L	205_Q	0.903	0.87
300_V	323_L	0.902	0.87
590_I	608_L	0.901	0.87
453_A	456_D	0.901	0.87
11_L	44_S	0.901	0.87
124_A	128_Y	0.897	0.86
590_I	596_I	0.895	0.86
506_L	527_L	0.892	0.86
151_I	192_V	0.890	0.86
433_I	440_A	0.890	0.86
132_F	199_L	0.890	0.86
140_E	235_A	0.888	0.86
497_A	517_G	0.887	0.86
110_D	114_R	0.885	0.86
357_L	360_T	0.885	0.86
497_A	507_E	0.879	0.85
398_F	442_M	0.879	0.85
499_G	537_S	0.879	0.85
216_T	219_Q	0.877	0.85
380_L	392_V	0.876	0.85
218_S	221_L	0.874	0.85
476_K	513_P	0.873	0.85
577_G	581_G	0.873	0.85
297_E	323_L	0.872	0.85
157_S	160_R	0.871	0.85
447_R	451_G	0.871	0.85
164_R	179_V	0.870	0.85
603_K	606_W	0.869	0.85
154_C	174_C	0.868	0.85
55_K	58_A	0.868	0.85
397_C	542_I	0.866	0.85
403_T	406_E	0.865	0.84
327_T	330_A	0.862	0.84
346_K	349_G	0.862	0.84
472_L	476_K	0.859	0.84
445_V	463_I	0.857	0.84
383_L	530_I	0.857	0.84
317_I	343_V	0.856	0.84
158_V	161_N	0.856	0.84
456_D	459_I	0.856	0.84
416_D	424_E	0.855	0.84
570_Q	574_K	0.853	0.84
22_R	88_Y	0.852	0.84
251_D	273_Q	0.852	0.84
210_L	236_V	0.852	0.84
326_K	343_V	0.850	0.83
53_S	57_E	0.850	0.83
251_D	274_G	0.849	0.83
14_V	39_L	0.849	0.83
209_Q	212_S	0.848	0.83
48_R	52_A	0.845	0.83
318_L	346_K	0.844	0.83
252_L	318_L	0.843	0.83
9_A	12_K	0.843	0.83
499_G	531_Q	0.839	0.83
319_L	323_L	0.836	0.82
384_A	389_L	0.835	0.82
40_K	44_S	0.832	0.82
115_L	145_L	0.831	0.82
556_S	559_E	0.830	0.82
400_I	408_T	0.828	0.82
499_G	507_E	0.825	0.82
299_F	303_F	0.822	0.81
428_Y	445_V	0.820	0.81
79_L	134_N	0.818	0.81
144_L	236_V	0.817	0.81
434_T	437_D	0.815	0.81
591_A	596_I	0.815	0.81
256_G	355_L	0.812	0.80
323_L	326_K	0.809	0.80
586_S	592_K	0.809	0.80
529_V	533_I	0.808	0.80
497_A	527_L	0.808	0.80
499_G	527_L	0.806	0.80
510_F	534_R	0.805	0.80
382_A	385_S	0.802	0.80
380_L	395_M	0.800	0.80
511_F	514_E	0.799	0.79
14_V	40_K	0.799	0.79
395_M	464_L	0.798	0.79
100_K	119_R	0.797	0.79
510_F	513_P	0.795	0.79
464_L	533_I	0.793	0.79
442_M	475_A	0.793	0.79
252_L	316_E	0.793	0.79
15_T	68_V	0.792	0.79
495_G	510_F	0.792	0.79
409_V	544_G	0.792	0.79
582_L	608_L	0.790	0.79
507_E	510_F	0.790	0.79
150_P	172_G	0.789	0.79
425_Y	539_D	0.789	0.79
297_E	324_S	0.788	0.78
72_H	360_T	0.786	0.78
480_A	483_D	0.784	0.78
156_N	159_Y	0.784	0.78
260_D	363_A	0.784	0.78
197_L	209_Q	0.780	0.78
453_A	459_I	0.780	0.78
583_R	608_L	0.778	0.78
191_Q	194_Y	0.777	0.77
83_N	277_L	0.777	0.77
22_R	69_T	0.776	0.77
300_V	319_L	0.776	0.77
464_L	509_L	0.773	0.77
556_S	569_R	0.771	0.77
330_A	334_S	0.771	0.77
115_L	142_L	0.771	0.77
528_H	531_Q	0.769	0.77
265_C	366_L	0.767	0.77
561_I	564_V	0.766	0.76
436_G	441_A	0.766	0.76
334_S	340_K	0.765	0.76
108_S	124_A	0.764	0.76
255_I	317_I	0.763	0.76
152_R	177_P	0.762	0.76
593_V	596_I	0.761	0.76
402_H	405_G	0.756	0.76
407_Q	548_K	0.755	0.75
334_S	337_A	0.755	0.75
439_Y	499_G	0.754	0.75
254_V	318_L	0.754	0.75
407_Q	429_N	0.752	0.75
446_L	465_I	0.750	0.75
193_E	197_L	0.750	0.75
282_Y	299_F	0.750	0.75
107_L	192_V	0.750	0.75
596_I	601_A	0.749	0.75
264_A	295_V	0.748	0.75
387_L	509_L	0.746	0.75
267_H	276_V	0.745	0.74
15_T	19_G	0.742	0.74
439_Y	473_A	0.742	0.74
397_C	411_S	0.741	0.74
15_T	38_D	0.737	0.74
137_A	238_R	0.737	0.74
83_N	275_K	0.736	0.74
138_V	142_L	0.736	0.74
585_A	593_V	0.734	0.73
269_L	276_V	0.731	0.73
538_H	542_I	0.730	0.73
144_L	232_Q	0.729	0.73
117_M	134_N	0.729	0.73
397_C	496_V	0.729	0.73
106_F	116_A	0.729	0.73
71_T	141_T	0.728	0.73
283_F	564_V	0.728	0.73
403_T	549_R	0.726	0.73
512_E	517_G	0.726	0.73
207_L	236_V	0.721	0.72
402_H	437_D	0.719	0.72
408_T	435_P	0.719	0.72
433_I	444_Q	0.717	0.72
580_Q	583_R	0.717	0.72
10_F	14_V	0.716	0.72
56_T	94_V	0.715	0.71
450_Y	479_F	0.714	0.71
403_T	408_T	0.713	0.71
463_I	493_L	0.711	0.71
507_E	537_S	0.710	0.71
233_I	237_R	0.710	0.71
571_M	574_K	0.709	0.71
412_C	463_I	0.708	0.71
512_E	527_L	0.707	0.71
432_G	435_P	0.707	0.71
433_I	441_A	0.704	0.70
22_R	33_V	0.704	0.70
591_A	602_E	0.704	0.70
146_Q	168_Q	0.702	0.70
31_I	62_Q	0.701	0.70
98_D	119_R	0.701	0.70
497_A	531_Q	0.699	0.70
496_V	534_R	0.698	0.70
384_A	391_E	0.697	0.69
471_Q	474_Q	0.696	0.69
377_H	381_T	0.696	0.69
478_V	481_E	0.695	0.69
52_A	57_E	0.695	0.69
69_T	279_S	0.695	0.69
477_N	480_A	0.695	0.69
296_V	323_L	0.695	0.69
156_N	162_R	0.693	0.69
132_F	410_A	0.693	0.69
169_Y	172_G	0.692	0.69
465_I	495_G	0.691	0.69
521_P	524_S	0.691	0.69
105_I	138_V	0.691	0.69
7_A	10_F	0.690	0.69
50_N	57_E	0.688	0.68
212_S	223_F	0.684	0.68
82_H	86_K	0.683	0.68
430_I	445_V	0.683	0.68
43_L	66_I	0.682	0.68
412_C	446_L	0.681	0.68
336_L	566_P	0.680	0.68
142_L	146_Q	0.680	0.68
154_C	166_C	0.679	0.67
15_T	21_Y	0.678	0.67
560_T	607_S	0.676	0.67
165_P	176_G	0.675	0.67
420_P	533_I	0.673	0.67
442_M	465_I	0.673	0.67
383_L	387_L	0.671	0.67
201_G	256_G	0.670	0.66
327_T	331_D	0.670	0.66
97_R	101_S	0.669	0.66
238_R	241_E	0.669	0.66
564_V	596_I	0.668	0.66
118_H	122_K	0.666	0.66
8_K	11_L	0.666	0.66
528_H	532_H	0.665	0.66
7_A	43_L	0.664	0.66
79_L	332_S	0.664	0.66
439_Y	471_Q	0.664	0.66
355_L	362_A	0.662	0.66
472_L	512_E	0.661	0.65
332_S	336_L	0.660	0.65
557_S	583_R	0.657	0.65
465_I	478_V	0.655	0.65
156_N	160_R	0.654	0.65
477_N	481_E	0.654	0.65
470_G	473_A	0.654	0.65
444_Q	448_R	0.653	0.64
116_A	155_E	0.652	0.64
558_L	561_I	0.652	0.64
251_D	315_G	0.651	0.64
588_E	598_Q	0.651	0.64
141_T	239_V	0.650	0.64
72_H	357_L	0.650	0.64
316_E	348_R	0.649	0.64
411_S	529_V	0.649	0.64
298_T	462_V	0.649	0.64
512_E	534_R	0.648	0.64
86_K	100_K	0.648	0.64
17_Q	38_D	0.648	0.64
7_A	14_V	0.648	0.64
162_R	179_V	0.648	0.64
497_A	506_L	0.647	0.64
298_T	301_G	0.644	0.63
106_F	125_K	0.644	0.63
52_A	56_T	0.644	0.63
323_L	329_L	0.643	0.63
58_A	61_A	0.643	0.63
271_I	276_V	0.643	0.63
364_T	367_T	0.642	0.63
411_S	543_G	0.641	0.63
10_F	66_I	0.641	0.63
564_V	568_R	0.640	0.63
58_A	91_R	0.639	0.63
407_Q	553_K	0.639	0.63
397_C	534_R	0.638	0.63
473_A	513_P	0.638	0.63
192_V	195_V	0.638	0.63
588_E	592_K	0.638	0.63
156_N	163_S	0.636	0.62
145_L	198_F	0.636	0.62
330_A	342_N	0.636	0.62
587_V	606_W	0.636	0.62
208_T	212_S	0.635	0.62
472_L	490_H	0.634	0.62
154_C	178_C	0.632	0.62
293_S	325_D	0.631	0.62
591_A	601_A	0.629	0.62
593_V	608_L	0.628	0.61
145_L	195_V	0.628	0.61
506_L	531_Q	0.627	0.61
23_M	43_L	0.625	0.61
230_R	234_Q	0.623	0.61
214_M	230_R	0.623	0.61
215_E	223_F	0.623	0.61
578_G	581_G	0.623	0.61
319_L	322_N	0.623	0.61
588_E	591_A	0.622	0.61
92_Y	195_V	0.620	0.60
88_Y	276_V	0.619	0.60
12_K	604_I	0.618	0.60
110_D	160_R	0.618	0.60
219_Q	334_S	0.617	0.60
123_H	126_G	0.616	0.60
9_A	13_T	0.615	0.60
334_S	341_I	0.615	0.60
117_M	135_G	0.615	0.60
321_F	347_P	0.615	0.60
510_F	537_S	0.613	0.60
168_Q	175_L	0.612	0.59
517_G	534_R	0.610	0.59
389_L	392_V	0.609	0.59
331_D	340_K	0.609	0.59
269_L	608_L	0.608	0.59
509_L	534_R	0.607	0.59
412_C	449_R	0.607	0.59
76_E	245_V	0.606	0.59
465_I	534_R	0.606	0.59
408_T	437_D	0.605	0.59
152_R	405_G	0.603	0.58
591_A	605_F	0.603	0.58
323_L	345_T	0.602	0.58
156_N	161_N	0.602	0.58
329_L	343_V	0.601	0.58
472_L	534_R	0.601	0.58
401_S	546_R	0.601	0.58
408_T	432_G	0.601	0.58
447_R	482_L	0.600	0.58
18_P	21_Y	0.600	0.58
521_P	526_A	0.600	0.58
433_I	436_G	0.599	0.58
49_S	52_A	0.597	0.58
330_A	340_K	0.597	0.58
532_H	535_D	0.597	0.58
576_M	590_I	0.596	0.57
527_L	535_D	0.596	0.57
63_I	66_I	0.595	0.57
245_V	276_V	0.594	0.57
405_G	545_H	0.593	0.57
383_L	529_V	0.593	0.57
576_M	585_A	0.593	0.57
256_G	368_S	0.592	0.57
485_S	490_H	0.592	0.57
105_I	142_L	0.592	0.57
559_E	579_L	0.591	0.57
499_G	517_G	0.591	0.57
167_L	170_Q	0.591	0.57
258_A	362_A	0.590	0.57
416_D	458_K	0.589	0.57
107_L	604_I	0.589	0.57
408_T	436_G	0.587	0.56
413_V	420_P	0.587	0.56
347_P	351_R	0.586	0.56
16_S	44_S	0.586	0.56
167_L	178_C	0.585	0.56
447_R	474_Q	0.585	0.56
24_Y	88_Y	0.585	0.56
39_L	46_Y	0.585	0.56
220_N	291_E	0.584	0.56
402_H	495_G	0.583	0.56
162_R	165_P	0.583	0.56
604_I	607_S	0.583	0.56
590_I	593_V	0.582	0.56
599_G	602_E	0.582	0.56
83_N	243_Q	0.582	0.56
17_Q	72_H	0.580	0.55
366_L	430_I	0.580	0.55
51_L	57_E	0.579	0.55
443_N	475_A	0.576	0.55
379_R	532_H	0.575	0.55
377_H	392_V	0.575	0.55
103_P	134_N	0.575	0.55
191_Q	195_V	0.575	0.55
564_V	597_S	0.574	0.55
132_F	196_R	0.574	0.55
535_D	538_H	0.574	0.55
378_Q	381_T	0.574	0.55
115_L	192_V	0.573	0.55
525_P	528_H	0.573	0.55
257_V	292_L	0.573	0.55
101_S	119_R	0.572	0.54
507_E	527_L	0.572	0.54
530_I	537_S	0.572	0.54
44_S	56_T	0.570	0.54
45_S	531_Q	0.570	0.54
546_R	549_R	0.568	0.54
334_S	339_R	0.568	0.54
29_T	88_Y	0.568	0.54
150_P	153_Q	0.567	0.54
101_S	118_H	0.566	0.54
190_Q	194_Y	0.566	0.54
237_R	240_T	0.566	0.54
451_G	454_I	0.565	0.54
257_V	320_D	0.565	0.54
463_I	475_A	0.564	0.53
212_S	340_K	0.564	0.53
257_V	296_V	0.563	0.53
459_I	491_P	0.563	0.53
140_E	143_A	0.562	0.53
267_H	281_S	0.562	0.53
106_F	128_Y	0.562	0.53
218_S	404_M	0.562	0.53
398_F	428_Y	0.561	0.53
571_M	595_G	0.559	0.53
571_M	596_I	0.559	0.53
149_F	195_V	0.557	0.53
82_H	96_L	0.556	0.52
121_A	124_A	0.555	0.52
11_L	47_F	0.555	0.52
196_R	200_S	0.554	0.52
432_G	436_G	0.554	0.52
250_D	315_G	0.554	0.52
563_G	603_K	0.554	0.52
58_A	92_Y	0.552	0.52
335_E	371_S	0.552	0.52
214_M	233_I	0.552	0.52
286_V	295_V	0.551	0.52
516_E	519_S	0.551	0.52
440_A	443_N	0.551	0.52
519_S	527_L	0.551	0.52
461_D	491_P	0.550	0.52
25_D	64_Q	0.550	0.52
604_I	609_K	0.549	0.51
507_E	531_Q	0.549	0.51
529_V	541_A	0.549	0.51
157_S	162_R	0.549	0.51
43_L	47_F	0.548	0.51
54_R	58_A	0.547	0.51
506_L	509_L	0.547	0.51
56_T	63_I	0.546	0.51
53_S	59_L	0.546	0.51
428_Y	447_R	0.546	0.51
600_L	607_S	0.544	0.51
281_S	365_A	0.543	0.51
603_K	607_S	0.542	0.51
593_V	605_F	0.542	0.51
561_I	607_S	0.541	0.50
439_Y	444_Q	0.540	0.50
229_I	233_I	0.540	0.50
263_M	369_K	0.540	0.50
84_Y	88_Y	0.540	0.50
476_K	485_S	0.539	0.50
136_Y	140_E	0.539	0.50
46_Y	56_T	0.539	0.50
108_S	144_L	0.539	0.50
395_M	420_P	0.539	0.50
425_Y	540_H	0.539	0.50
407_Q	545_H	0.538	0.50
557_S	608_L	0.538	0.50
72_H	76_E	0.538	0.50
137_A	141_T	0.537	0.50
15_T	70_V	0.537	0.50
402_H	541_A	0.536	0.50
328_L	331_D	0.536	0.50
44_S	47_F	0.536	0.50
143_A	173_R	0.535	0.50
545_H	550_A	0.535	0.50
542_I	551_K	0.534	0.50
415_F	529_V	0.534	0.50
512_E	537_S	0.534	0.50
41_K	45_S	0.533	0.49
531_Q	537_S	0.532	0.49
561_I	582_L	0.532	0.49
329_L	333_L	0.532	0.49
26_A	185_E	0.532	0.49
370_L	478_V	0.530	0.49
454_I	484_V	0.530	0.49
549_R	553_K	0.529	0.49
197_L	206_V	0.529	0.49
55_K	88_Y	0.528	0.49
97_R	133_P	0.528	0.49
245_V	361_N	0.528	0.49
253_D	272_R	0.527	0.49
586_S	605_F	0.527	0.49
408_T	544_G	0.527	0.49
450_Y	453_A	0.526	0.48
374_S	378_Q	0.525	0.48
411_S	507_E	0.525	0.48
211_I	219_Q	0.525	0.48
293_S	324_S	0.525	0.48
439_Y	507_E	0.524	0.48
302_Q	403_T	0.524	0.48
510_F	527_L	0.524	0.48
583_R	586_S	0.523	0.48
395_M	463_I	0.523	0.48
33_V	442_M	0.521	0.48
31_I	527_L	0.520	0.48
440_A	478_V	0.520	0.48
472_L	475_A	0.520	0.48
397_C	507_E	0.520	0.48
485_S	491_P	0.519	0.48
496_V	499_G	0.519	0.48
50_N	53_S	0.518	0.47
522_P	525_P	0.517	0.47
193_E	322_N	0.516	0.47
158_V	168_Q	0.516	0.47
450_Y	484_V	0.516	0.47
562_E	607_S	0.516	0.47
105_I	433_I	0.515	0.47
23_M	71_T	0.514	0.47
559_E	578_G	0.514	0.47
575_Y	585_A	0.514	0.47
151_I	191_Q	0.513	0.47
59_L	88_Y	0.513	0.47
322_N	347_P	0.513	0.47
218_S	521_P	0.512	0.47
334_S	338_G	0.512	0.47
439_Y	534_R	0.512	0.47
219_Q	462_V	0.511	0.47
578_G	590_I	0.511	0.47
398_F	460_P	0.511	0.47
508_T	512_E	0.511	0.47
276_V	279_S	0.511	0.47
423_A	589_E	0.510	0.46
194_Y	232_Q	0.510	0.46
512_E	515_G	0.510	0.46
51_L	56_T	0.509	0.46
257_V	301_G	0.508	0.46
205_Q	233_I	0.508	0.46
282_Y	470_G	0.508	0.46
590_I	607_S	0.508	0.46
86_K	99_D	0.507	0.46
158_V	483_D	0.507	0.46
47_F	60_V	0.507	0.46
525_P	532_H	0.507	0.46
193_E	225_E	0.507	0.46
72_H	586_S	0.507	0.46
218_S	238_R	0.506	0.46
266_V	284_P	0.505	0.46
439_Y	442_M	0.504	0.46
188_Y	192_V	0.504	0.46
508_T	534_R	0.504	0.46
449_R	460_P	0.504	0.46
405_G	408_T	0.504	0.46
117_M	239_V	0.503	0.46
105_I	197_L	0.503	0.46
212_S	347_P	0.501	0.45
59_L	65_Q	0.501	0.45
206_V	597_S	0.500	0.45
469_K	515_G	0.500	0.45

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3c65A	1	0.2459	100	0.639	Contact Map
2nrtA	1	0.3541	100	0.649	Contact Map
2nrrA	1	0.2262	100	0.718	Contact Map
2bgwA	2	0.3492	100	0.831	Contact Map
1yd6A	5	0.159	100	0.842	Contact Map
1yd0A	1	0.1459	100	0.849	Contact Map
2wshA	4	0.1525	100	0.854	Contact Map
3gocA	2	0.3557	100	0.857	Contact Map
2w36A	1	0.2918	100	0.873	Contact Map
4gfjA	1	0.7164	100	0.88	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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