GREMLIN Database
YFCN - UPF0115 protein YfcN
UniProt: P0A8B2 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG14117
Length: 183 (168)
Sequences: 1529 (1161)
Seq/√Len: 89.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
112_L129_V5.1121.00
162_Y169_L3.7351.00
96_L115_L3.0441.00
97_F130_M2.9091.00
119_C124_V2.8741.00
19_M22_T2.7621.00
119_C127_A2.5611.00
95_E124_V2.5381.00
116_I127_A2.4901.00
120_R151_H2.4691.00
96_L124_V2.4111.00
83_E92_Y2.4021.00
103_L111_E2.2771.00
159_P169_L2.2521.00
130_M166_A2.2411.00
143_P147_A2.1621.00
133_H166_A2.1521.00
157_Q165_D2.1481.00
142_T168_L2.0581.00
126_C171_L1.9741.00
15_F19_M1.9221.00
159_P162_Y1.9031.00
128_C169_L1.8941.00
101_H108_A1.8301.00
104_T107_Q1.7681.00
133_H165_D1.7551.00
54_A57_Y1.7471.00
56_H59_S1.7381.00
80_S83_E1.6281.00
18_L21_G1.6031.00
127_A170_V1.5911.00
134_G138_L1.5811.00
10_E13_A1.5521.00
115_L127_A1.5461.00
106_L109_K1.5391.00
143_P157_Q1.5131.00
108_A138_L1.5001.00
72_V143_P1.4650.99
9_E13_A1.4470.99
13_A17_Q1.4190.99
10_E14_L1.3790.99
118_A122_E1.3720.99
21_G24_K1.3600.99
146_L152_V1.3310.99
131_H151_H1.3250.99
11_D14_L1.3240.99
109_K148_Q1.3050.99
152_V170_V1.2840.99
139_K157_Q1.2470.98
160_K166_A1.2400.98
114_A118_A1.2370.98
99_D108_A1.2180.98
79_V153_M1.1940.98
80_S131_H1.1890.98
82_F88_R1.1870.98
34_P38_K1.1820.98
86_K92_Y1.1820.98
153_M171_L1.1730.98
45_K48_I1.1650.97
79_V87_L1.1580.97
17_Q20_A1.1510.97
50_E61_E1.1510.97
118_A121_R1.1460.97
99_D102_G1.1450.97
154_A171_L1.1410.97
15_F18_L1.1300.97
140_Q143_P1.1230.97
43_P46_R1.1200.97
74_Y131_H1.1190.97
30_I33_R1.1140.97
101_H166_A1.1130.97
128_C164_G1.1110.97
119_C123_H1.0920.96
99_D166_A1.0890.96
138_L171_L1.0730.96
131_H168_L1.0730.96
96_L119_C1.0410.95
40_S43_P1.0380.95
131_H142_T1.0360.95
128_C158_A1.0270.95
103_L138_L1.0220.94
12_Q16_R1.0120.94
52_A55_S1.0110.94
48_I52_A1.0090.94
136_H139_K1.0000.94
75_V84_A0.9780.93
105_Q141_Q0.9670.93
101_H138_L0.9630.93
50_E53_D0.9600.92
128_C163_G0.9590.92
82_F169_L0.9580.92
84_A156_H0.9480.92
37_K47_L0.9420.92
116_I149_H0.9340.91
98_L115_L0.9340.91
155_F168_L0.9280.91
98_L127_A0.9250.91
86_K125_F0.9250.91
128_C162_Y0.9230.91
164_G169_L0.9210.91
81_H127_A0.9200.91
73_K84_A0.9190.91
80_S84_A0.9120.90
39_I43_P0.9060.90
83_E86_K0.9030.90
45_K49_Q0.8690.88
86_K91_D0.8650.88
99_D138_L0.8620.88
102_G112_L0.8510.87
127_A172_I0.8470.87
97_F136_H0.8430.87
46_R49_Q0.8330.86
156_H171_L0.8330.86
82_F86_K0.8230.85
12_Q89_R0.8220.85
15_F21_G0.8070.84
109_K150_P0.8050.84
82_F85_K0.7980.83
138_L143_P0.7910.83
49_Q52_A0.7880.83
79_V83_E0.7830.82
8_S11_D0.7760.82
130_M133_H0.7710.81
85_K118_A0.7700.81
111_E118_A0.7700.81
72_V168_L0.7690.81
80_S125_F0.7680.81
95_E162_Y0.7670.81
36_R40_S0.7650.81
82_F92_Y0.7640.81
78_D154_A0.7620.80
104_T138_L0.7580.80
57_Y60_D0.7540.80
103_L107_Q0.7490.79
169_L174_V0.7480.79
95_E125_F0.7450.79
134_G143_P0.7420.79
104_T111_E0.7380.78
136_H140_Q0.7350.78
129_V170_V0.7330.78
108_A136_H0.7270.77
23_R45_K0.7250.77
38_K42_V0.7250.77
43_P47_L0.7250.77
68_T93_S0.7240.77
15_F131_H0.7240.77
76_R173_E0.7220.77
13_A28_D0.7160.76
32_H35_Q0.7140.76
84_A88_R0.7100.76
43_P48_I0.7080.75
8_S12_Q0.7050.75
94_P161_E0.7040.75
14_L112_L0.7030.75
97_F133_H0.7000.75
100_L103_L0.6980.74
50_E55_S0.6930.74
88_R156_H0.6890.73
29_T37_K0.6870.73
147_A157_Q0.6860.73
75_V79_V0.6830.73
51_Q59_S0.6810.73
130_M168_L0.6800.72
17_Q35_Q0.6740.72
15_F74_Y0.6720.72
24_K113_G0.6710.71
87_L154_A0.6680.71
79_V138_L0.6650.71
39_I49_Q0.6640.71
9_E23_R0.6630.71
35_Q41_E0.6630.71
139_K171_L0.6620.70
35_Q61_E0.6610.70
28_D32_H0.6600.70
53_D57_Y0.6600.70
12_Q17_Q0.6500.69
96_L127_A0.6500.69
32_H42_V0.6460.69
136_H143_P0.6460.69
105_Q137_I0.6400.68
105_Q138_L0.6390.68
18_L89_R0.6350.67
44_V49_Q0.6340.67
131_H149_H0.6320.67
144_L148_Q0.6260.66
101_H139_K0.6250.66
101_H104_T0.6220.66
142_T166_A0.6200.65
32_H36_R0.6180.65
58_F109_K0.6180.65
64_P68_T0.6150.65
76_R150_P0.6130.65
14_L18_L0.6080.64
92_Y157_Q0.6080.64
143_P155_F0.6080.64
124_V127_A0.6070.64
24_K106_L0.6060.64
41_E45_K0.6050.63
15_F149_H0.6030.63
80_S141_Q0.5950.62
101_H133_H0.5940.62
87_L148_Q0.5930.62
46_R50_E0.5880.61
115_L166_A0.5860.61
28_D40_S0.5860.61
99_D104_T0.5820.61
103_L113_G0.5780.60
94_P162_Y0.5730.59
71_P156_H0.5720.59
61_E69_E0.5690.59
98_L111_E0.5690.59
8_S13_A0.5690.59
50_E59_S0.5660.58
59_S62_F0.5610.58
128_C159_P0.5560.57
85_K139_K0.5550.57
145_W173_E0.5540.57
80_S157_Q0.5530.57
78_D83_E0.5500.56
117_A151_H0.5470.56
31_V40_S0.5460.56
36_R49_Q0.5450.56
80_S92_Y0.5420.55
24_K27_Q0.5420.55
44_V47_L0.5410.55
40_S46_R0.5390.55
84_A92_Y0.5390.55
80_S90_G0.5380.55
158_A164_G0.5370.54
163_G169_L0.5340.54
113_G141_Q0.5340.54
101_H136_H0.5340.54
158_A163_G0.5320.54
11_D90_G0.5320.54
115_L130_M0.5310.54
54_A60_D0.5280.53
10_E77_P0.5270.53
109_K145_W0.5250.53
20_A175_E0.5250.53
81_H138_L0.5250.53
48_I93_S0.5220.52
63_Q67_N0.5220.52
87_L126_C0.5180.52
98_L148_Q0.5170.52
15_F84_A0.5140.51
82_F174_V0.5140.51
32_H52_A0.5100.51
45_K52_A0.5100.51
35_Q38_K0.5070.50
85_K99_D0.5050.50
94_P159_P0.5040.50
101_H130_M0.5000.49
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3qd7X 1 0.6831 100 0.373 Contact Map
4od6A 1 0.4481 100 0.515 Contact Map
2zqeA 1 0.4372 100 0.521 Contact Map
2d9iA 1 0.4645 99.8 0.622 Contact Map
2vkcA 1 0.5137 99.8 0.641 Contact Map
3fauA 3 0.388 99.8 0.649 Contact Map
3lubA 4 0.9071 25.8 0.944 Contact Map
2mi9A 1 0.1585 14.9 0.95 Contact Map
4r1dB 1 0.153 13.1 0.951 Contact Map
5aj3g 1 0.5628 12.3 0.952 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0073 seconds.