DCTA - ECOLI - GREMLIN Contacts

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DCTA - Aerobic C4-dicarboxylate transport protein

UniProt:	P0A830	Sequences: MKTSLFKSLYFQVLTAIAIGILLGHFYPEIGEQMKPLGDGFVKLIKMIIAPVIFCTVVTGIAGMESMKAVGRTGAVALLYFEIVSTIALIIGLIIVNVVQPGAGMNVDPATLDAKAVAVYADQAKDQGIVAFIMDVIPASVIGAFASGNILQVLLFAVLFGFALHRLGSKGQLIFNVIESFSQVIFGIINMIMRLAPIGAFGAMAFTIGKYGVGTLVQLGQLIICFYITCILFVVLVLGSIAKATGFSIFKFIRYIREELLIVLGTSSSESALPRMLDKMEKLGCRKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNSQMDIVHQITLLIVLLLSSKGAAGVTGSGFIVLAATLSAVGHLPVAGLALILGIDRFMSEARALTNLVGNGVATIVVAKWVKELDHKKLDDVLNNRAPDGKTHELSS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG20044
Length:	428 (393)
Sequences:	6279 (3711)
Seq/√Len:	187.2

ECOLI - DCTA GLTP YDJN SSTT
BACSU - GLTT DCTA GLTP TCYP
HALSA - Q9HHN5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
143_G	147_S	4.583	1.00
172_Q	176_N	3.697	1.00
281_E	287_K	3.427	1.00
97_N	329_Q	3.144	1.00
95_I	229_T	3.094	1.00
169_S	172_Q	3.065	1.00
19_I	201_F	3.040	1.00
76_V	402_V	3.025	1.00
136_V	155_L	2.956	1.00
54_F	157_A	2.887	1.00
35_K	39_D	2.782	1.00
58_V	178_I	2.770	1.00
40_G	137_I	2.716	1.00
23_L	201_F	2.655	1.00
273_L	294_I	2.635	1.00
12_Q	194_R	2.596	1.00
286_R	404_E	2.562	1.00
187_G	190_N	2.491	1.00
173_L	180_S	2.488	1.00
54_F	58_V	2.483	1.00
100_Q	103_A	2.463	1.00
400_K	407_H	2.427	1.00
55_C	181_F	2.424	1.00
325_D	328_H	2.405	1.00
37_L	202_G	2.401	1.00
8_S	11_F	2.309	1.00
286_R	399_A	2.271	1.00
227_Y	382_A	2.257	1.00
160_F	184_V	2.250	1.00
260_L	389_V	2.242	1.00
131_A	135_D	2.178	1.00
224_I	228_I	2.170	1.00
84_V	241_I	2.129	1.00
168_G	171_G	2.128	1.00
80_Y	394_A	2.096	1.00
76_V	401_W	2.027	1.00
259_E	279_K	2.026	1.00
14_L	18_A	1.979	1.00
95_I	232_L	1.976	1.00
243_K	246_G	1.971	1.00
22_L	26_F	1.966	1.00
90_I	94_I	1.911	1.00
99_V	225_C	1.906	1.00
174_I	177_V	1.902	1.00
173_L	176_N	1.895	1.00
94_I	98_V	1.893	1.00
139_A	143_G	1.879	1.00
16_A	201_F	1.876	1.00
316_I	368_G	1.853	1.00
75_A	79_L	1.835	1.00
63_G	179_E	1.834	1.00
149_N	152_Q	1.832	1.00
230_C	382_A	1.829	1.00
96_V	314_V	1.826	1.00
285_C	396_I	1.809	1.00
280_M	392_G	1.781	1.00
55_C	185_I	1.781	1.00
48_I	192_I	1.780	1.00
101_P	318_Q	1.766	1.00
376_D	383_R	1.764	1.00
217_V	221_Q	1.762	1.00
278_D	282_K	1.742	1.00
174_I	180_S	1.732	1.00
232_L	236_L	1.706	1.00
7_K	11_F	1.695	1.00
72_R	402_V	1.685	1.00
166_R	187_G	1.684	1.00
164_L	184_V	1.673	1.00
174_I	184_V	1.671	1.00
293_V	395_T	1.666	1.00
99_V	228_I	1.660	1.00
141_V	156_F	1.645	1.00
245_T	400_K	1.629	1.00
255_Y	283_L	1.627	1.00
256_I	392_G	1.622	1.00
285_C	399_A	1.614	1.00
95_I	225_C	1.609	1.00
142_I	145_F	1.606	1.00
96_V	311_M	1.603	1.00
16_A	20_G	1.602	1.00
323_Q	327_V	1.558	1.00
220_G	224_I	1.551	1.00
320_T	368_G	1.542	1.00
316_I	364_L	1.532	1.00
276_M	392_G	1.531	1.00
230_C	386_T	1.528	1.00
380_S	384_A	1.523	1.00
142_I	146_A	1.514	1.00
40_G	134_M	1.510	1.00
251_K	254_R	1.494	1.00
229_T	307_I	1.489	1.00
242_A	393_V	1.472	1.00
62_A	175_F	1.463	1.00
170_K	183_Q	1.429	1.00
163_A	188_I	1.423	1.00
260_L	385_L	1.420	1.00
46_K	139_A	1.416	1.00
177_V	180_S	1.407	1.00
277_L	290_V	1.404	1.00
399_A	405_L	1.403	1.00
54_F	145_F	1.402	1.00
255_Y	282_K	1.381	1.00
250_F	254_R	1.381	1.00
281_E	290_V	1.379	1.00
39_D	43_K	1.368	1.00
241_I	397_V	1.362	1.00
11_F	15_T	1.353	1.00
167_L	171_G	1.352	1.00
135_D	149_N	1.349	1.00
43_K	139_A	1.348	1.00
179_E	183_Q	1.348	1.00
270_E	345_G	1.345	1.00
166_R	191_M	1.339	1.00
326_I	330_I	1.326	1.00
59_T	178_I	1.322	1.00
61_I	158_V	1.322	1.00
47_M	156_F	1.318	1.00
23_L	27_Y	1.302	1.00
225_C	311_M	1.298	1.00
286_R	289_V	1.295	1.00
106_N	321_N	1.290	1.00
53_I	150_I	1.287	1.00
77_A	293_V	1.281	1.00
173_L	177_V	1.279	1.00
93_L	329_Q	1.268	1.00
28_P	209_G	1.258	1.00
137_I	155_L	1.255	1.00
190_N	278_D	1.254	1.00
299_S	302_L	1.247	1.00
256_I	389_V	1.239	1.00
106_N	109_P	1.235	1.00
7_K	15_T	1.232	1.00
163_A	191_M	1.231	1.00
289_V	399_A	1.228	1.00
17_I	204_M	1.225	1.00
248_S	251_K	1.219	1.00
276_M	294_I	1.217	1.00
235_V	239_G	1.213	1.00
160_F	181_F	1.212	1.00
164_L	174_I	1.208	1.00
218_Q	221_Q	1.197	1.00
206_F	210_K	1.193	1.00
223_I	375_I	1.184	1.00
313_A	332_L	1.174	1.00
191_M	195_L	1.174	1.00
185_I	189_I	1.170	1.00
323_Q	328_H	1.170	1.00
399_A	403_K	1.163	1.00
27_Y	30_I	1.161	1.00
79_L	83_I	1.148	1.00
332_L	361_V	1.146	1.00
128_G	131_A	1.145	1.00
159_L	188_I	1.145	1.00
48_I	189_I	1.138	1.00
234_V	386_T	1.134	1.00
263_V	384_A	1.132	1.00
35_K	206_F	1.131	1.00
94_I	97_N	1.126	1.00
69_A	288_S	1.126	1.00
167_L	180_S	1.122	1.00
236_L	239_G	1.119	1.00
158_V	162_F	1.109	1.00
72_R	76_V	1.109	1.00
221_Q	224_I	1.107	1.00
168_G	172_Q	1.105	1.00
272_A	276_M	1.104	1.00
81_F	293_V	1.100	1.00
252_F	256_I	1.097	1.00
351_F	373_L	1.085	1.00
308_Y	376_D	1.084	1.00
247_F	405_L	1.079	1.00
172_Q	175_F	1.077	1.00
50_A	153_V	1.077	1.00
246_G	400_K	1.070	1.00
12_Q	16_A	1.070	1.00
399_A	404_E	1.066	1.00
40_G	44_L	1.066	1.00
273_L	298_Y	1.064	1.00
242_A	247_F	1.063	1.00
258_E	282_K	1.061	1.00
280_M	294_I	1.061	1.00
176_N	180_S	1.058	1.00
143_G	146_A	1.054	1.00
243_K	248_S	1.052	1.00
217_V	220_G	1.051	1.00
84_V	303_D	1.049	1.00
73_T	289_V	1.047	1.00
330_I	334_I	1.046	1.00
57_V	154_L	1.041	1.00
303_D	340_S	1.039	1.00
83_I	87_I	1.039	1.00
37_L	195_L	1.029	1.00
276_M	388_L	1.028	1.00
22_L	25_H	1.026	1.00
55_C	59_T	1.024	1.00
18_A	22_L	1.022	1.00
267_S	377_R	1.021	1.00
90_I	333_L	1.013	1.00
102_G	318_Q	1.009	1.00
106_N	110_A	1.008	0.99
305_T	350_G	1.001	0.99
223_I	378_F	1.000	0.99
90_I	330_I	0.998	0.99
174_I	178_I	0.994	0.99
308_Y	383_R	0.989	0.99
214_G	217_V	0.985	0.99
195_L	198_I	0.984	0.99
23_L	205_A	0.983	0.99
247_F	251_K	0.975	0.99
240_S	243_K	0.974	0.99
29_E	32_E	0.966	0.99
167_L	184_V	0.962	0.99
285_C	290_V	0.960	0.99
176_N	179_E	0.958	0.99
400_K	403_K	0.957	0.99
238_L	241_I	0.954	0.99
221_Q	318_Q	0.951	0.99
280_M	285_C	0.949	0.99
92_G	310_T	0.948	0.99
95_I	99_V	0.948	0.99
233_F	237_V	0.943	0.99
82_E	86_T	0.941	0.99
124_A	127_Q	0.935	0.99
347_T	380_S	0.934	0.99
19_I	23_L	0.933	0.99
233_F	307_I	0.928	0.99
254_R	257_R	0.926	0.99
23_L	34_M	0.924	0.99
38_G	203_A	0.924	0.99
326_I	329_Q	0.923	0.99
107_V	110_A	0.922	0.99
155_L	159_L	0.921	0.99
272_A	275_R	0.920	0.99
66_S	69_A	0.920	0.99
255_Y	279_K	0.919	0.99
187_G	191_M	0.918	0.99
309_L	354_L	0.912	0.99
281_E	291_G	0.910	0.99
88_A	233_F	0.910	0.99
141_V	146_A	0.909	0.99
301_N	391_N	0.903	0.99
280_M	290_V	0.902	0.99
223_I	379_M	0.901	0.99
279_K	282_K	0.899	0.99
314_V	329_Q	0.898	0.99
259_E	276_M	0.896	0.99
226_F	379_M	0.894	0.99
255_Y	259_E	0.893	0.99
205_A	209_G	0.891	0.99
171_G	180_S	0.889	0.99
86_T	90_I	0.888	0.99
226_F	311_M	0.887	0.99
91_I	232_L	0.887	0.99
127_Q	131_A	0.884	0.99
30_I	33_Q	0.884	0.99
48_I	188_I	0.882	0.99
259_E	272_A	0.881	0.99
264_L	381_E	0.881	0.99
127_Q	135_D	0.881	0.99
133_I	137_I	0.877	0.99
308_Y	379_M	0.872	0.99
278_D	281_E	0.870	0.99
160_F	188_I	0.868	0.98
227_Y	231_I	0.866	0.98
162_F	166_R	0.864	0.98
43_K	46_K	0.864	0.98
239_G	253_I	0.862	0.98
33_Q	36_P	0.861	0.98
131_A	134_M	0.858	0.98
339_S	357_T	0.858	0.98
269_S	387_N	0.856	0.98
132_F	138_P	0.856	0.98
34_M	205_A	0.855	0.98
355_A	369_L	0.852	0.98
320_T	367_A	0.850	0.98
237_V	241_I	0.850	0.98
257_R	261_L	0.848	0.98
8_S	12_Q	0.846	0.98
59_T	179_E	0.846	0.98
134_M	138_P	0.845	0.98
262_I	272_A	0.843	0.98
55_C	178_I	0.842	0.98
58_V	164_L	0.841	0.98
157_A	161_G	0.837	0.98
93_L	97_N	0.837	0.98
302_L	391_N	0.837	0.98
7_K	12_Q	0.837	0.98
289_V	293_V	0.835	0.98
130_V	134_M	0.829	0.98
159_L	191_M	0.829	0.98
144_A	156_F	0.827	0.98
252_F	392_G	0.825	0.98
228_I	231_I	0.825	0.98
164_L	178_I	0.821	0.98
238_L	242_A	0.819	0.98
34_M	202_G	0.818	0.98
262_I	275_R	0.816	0.98
141_V	144_A	0.812	0.98
236_L	240_S	0.810	0.98
38_G	199_G	0.810	0.98
239_G	243_K	0.807	0.98
137_I	140_S	0.807	0.98
190_N	194_R	0.806	0.98
351_F	369_L	0.805	0.98
27_Y	34_M	0.804	0.98
141_V	148_G	0.803	0.98
129_I	133_I	0.803	0.98
73_T	398_V	0.803	0.98
324_M	328_H	0.801	0.97
168_G	175_F	0.800	0.97
108_D	111_T	0.800	0.97
145_F	156_F	0.797	0.97
262_I	266_T	0.796	0.97
201_F	205_A	0.794	0.97
140_S	156_F	0.792	0.97
182_S	186_F	0.791	0.97
95_I	228_I	0.790	0.97
400_K	405_L	0.789	0.97
312_A	372_I	0.788	0.97
177_V	181_F	0.788	0.97
125_K	128_G	0.787	0.97
92_G	311_M	0.784	0.97
58_V	160_F	0.780	0.97
399_A	406_D	0.779	0.97
228_I	232_L	0.777	0.97
222_L	311_M	0.774	0.97
252_F	396_I	0.773	0.97
39_D	134_M	0.772	0.97
171_G	175_F	0.771	0.97
309_L	351_F	0.770	0.97
27_Y	205_A	0.762	0.97
223_I	227_Y	0.761	0.97
41_F	196_A	0.760	0.97
67_M	162_F	0.759	0.96
231_I	235_V	0.758	0.96
56_T	182_S	0.756	0.96
222_L	379_M	0.753	0.96
355_A	359_S	0.752	0.96
132_F	135_D	0.751	0.96
259_E	275_R	0.748	0.96
298_Y	391_N	0.748	0.96
300_F	341_K	0.747	0.96
100_Q	318_Q	0.746	0.96
263_V	388_L	0.744	0.96
58_V	157_A	0.742	0.96
222_L	308_Y	0.742	0.96
222_L	372_I	0.740	0.96
156_F	160_F	0.733	0.96
267_S	380_S	0.732	0.96
29_E	209_G	0.731	0.96
64_M	73_T	0.727	0.96
196_A	199_G	0.722	0.95
226_F	230_C	0.721	0.95
13_V	196_A	0.715	0.95
101_P	104_G	0.715	0.95
134_M	137_I	0.714	0.95
30_I	34_M	0.714	0.95
33_Q	37_L	0.712	0.95
44_L	137_I	0.711	0.95
185_I	192_I	0.710	0.95
225_C	228_I	0.710	0.95
95_I	98_V	0.708	0.95
68_K	71_G	0.708	0.95
244_A	397_V	0.706	0.95
305_T	309_L	0.706	0.95
145_F	152_Q	0.705	0.95
23_L	31_G	0.705	0.95
313_A	357_T	0.704	0.95
276_M	391_N	0.703	0.95
229_T	311_M	0.699	0.94
251_K	255_Y	0.695	0.94
183_Q	187_G	0.695	0.94
167_L	183_Q	0.693	0.94
351_F	379_M	0.693	0.94
305_T	343_A	0.693	0.94
155_L	195_L	0.692	0.94
20_G	205_A	0.692	0.94
62_A	165_H	0.691	0.94
247_F	406_D	0.690	0.94
41_F	195_L	0.679	0.94
135_D	138_P	0.679	0.94
296_T	300_F	0.678	0.94
235_V	240_S	0.678	0.94
404_E	407_H	0.676	0.93
170_K	176_N	0.676	0.93
242_A	245_T	0.673	0.93
327_V	331_T	0.672	0.93
28_P	32_E	0.671	0.93
79_L	82_E	0.670	0.93
81_F	394_A	0.670	0.93
86_T	337_L	0.668	0.93
200_A	347_T	0.666	0.93
91_I	229_T	0.662	0.93
189_I	264_L	0.662	0.93
82_E	341_K	0.657	0.92
12_Q	198_I	0.656	0.92
58_V	181_F	0.655	0.92
343_A	353_V	0.650	0.92
298_Y	302_L	0.649	0.92
196_A	266_T	0.649	0.92
356_A	362_G	0.645	0.92
40_G	155_L	0.645	0.92
77_A	398_V	0.644	0.92
15_T	19_I	0.644	0.92
97_N	326_I	0.644	0.92
84_V	88_A	0.643	0.92
341_K	391_N	0.643	0.92
317_A	322_S	0.642	0.92
327_V	330_I	0.642	0.92
287_K	291_G	0.642	0.92
247_F	255_Y	0.640	0.91
160_F	174_I	0.640	0.91
43_K	135_D	0.639	0.91
365_P	368_G	0.638	0.91
309_L	343_A	0.638	0.91
313_A	317_A	0.633	0.91
65_E	68_K	0.632	0.91
179_E	182_S	0.632	0.91
32_E	209_G	0.632	0.91
336_L	353_V	0.631	0.91
331_T	361_V	0.631	0.91
294_I	395_T	0.630	0.91
140_S	144_A	0.627	0.91
243_K	249_I	0.627	0.91
92_G	307_I	0.625	0.90
233_F	303_D	0.624	0.90
23_L	30_I	0.624	0.90
198_I	202_G	0.621	0.90
345_G	348_G	0.621	0.90
172_Q	177_V	0.621	0.90
222_L	312_A	0.620	0.90
30_I	209_G	0.618	0.90
180_S	183_Q	0.617	0.90
121_A	124_A	0.615	0.90
368_G	371_L	0.614	0.90
44_L	159_L	0.614	0.90
123_Q	126_D	0.613	0.90
104_G	221_Q	0.612	0.90
171_G	184_V	0.608	0.89
91_I	237_V	0.607	0.89
37_L	198_I	0.604	0.89
69_A	404_E	0.603	0.89
81_F	391_N	0.603	0.89
329_Q	333_L	0.602	0.89
256_I	276_M	0.601	0.89
309_L	313_A	0.601	0.89
180_S	184_V	0.600	0.89
44_L	195_L	0.599	0.89
128_G	132_F	0.599	0.89
277_L	294_I	0.597	0.88
69_A	72_R	0.597	0.88
59_T	63_G	0.596	0.88
66_S	74_G	0.596	0.88
302_L	343_A	0.596	0.88
267_S	271_S	0.595	0.88
164_L	175_F	0.595	0.88
395_T	399_A	0.594	0.88
95_I	224_I	0.593	0.88
270_E	298_Y	0.590	0.88
69_A	74_G	0.590	0.88
283_L	396_I	0.590	0.88
323_Q	326_I	0.589	0.88
120_Y	123_Q	0.587	0.88
81_F	233_F	0.587	0.88
333_L	336_L	0.587	0.88
335_V	360_A	0.586	0.87
397_V	401_W	0.586	0.87
144_A	148_G	0.585	0.87
275_R	278_D	0.583	0.87
87_I	90_I	0.582	0.87
222_L	230_C	0.581	0.87
252_F	283_L	0.581	0.87
345_G	349_S	0.579	0.87
50_A	145_F	0.579	0.87
92_G	308_Y	0.577	0.87
331_T	335_V	0.575	0.86
199_G	203_A	0.575	0.86
20_G	24_G	0.571	0.86
72_R	75_A	0.571	0.86
146_A	149_N	0.570	0.86
288_S	404_E	0.570	0.86
47_M	188_I	0.569	0.86
84_V	300_F	0.569	0.86
31_G	209_G	0.568	0.86
224_I	227_Y	0.567	0.86
328_H	331_T	0.567	0.86
121_A	125_K	0.566	0.86
303_D	390_G	0.564	0.85
272_A	298_Y	0.563	0.85
310_T	336_L	0.562	0.85
254_R	258_E	0.562	0.85
305_T	383_R	0.561	0.85
104_G	218_Q	0.560	0.85
313_A	316_I	0.560	0.85
9_L	12_Q	0.559	0.85
59_T	175_F	0.557	0.85
312_A	376_D	0.557	0.85
25_H	213_V	0.557	0.85
219_L	222_L	0.555	0.85
221_Q	225_C	0.554	0.84
174_I	181_F	0.553	0.84
154_L	320_T	0.552	0.84
403_K	407_H	0.552	0.84
18_A	407_H	0.552	0.84
285_C	395_T	0.551	0.84
263_V	385_L	0.549	0.84
97_N	314_V	0.549	0.84
73_T	402_V	0.549	0.84
387_N	391_N	0.547	0.84
23_L	26_F	0.547	0.84
88_A	307_I	0.547	0.84
284_G	406_D	0.547	0.84
333_L	337_L	0.546	0.84
164_L	180_S	0.546	0.84
286_R	290_V	0.546	0.84
52_V	154_L	0.546	0.84
175_F	179_E	0.546	0.84
44_L	192_I	0.544	0.83
350_G	357_T	0.544	0.83
308_Y	312_A	0.543	0.83
263_V	380_S	0.542	0.83
355_A	366_V	0.540	0.83
187_G	194_R	0.540	0.83
172_Q	180_S	0.537	0.83
167_L	187_G	0.537	0.83
394_A	397_V	0.536	0.82
28_P	31_G	0.534	0.82
238_L	243_K	0.533	0.82
289_V	404_E	0.532	0.82
361_V	364_L	0.531	0.82
16_A	220_G	0.531	0.82
48_I	52_V	0.531	0.82
239_G	250_F	0.531	0.82
272_A	388_L	0.531	0.82
100_Q	314_V	0.529	0.82
348_G	352_I	0.529	0.82
27_Y	209_G	0.528	0.82
306_S	337_L	0.527	0.81
250_F	253_I	0.527	0.81
177_V	184_V	0.526	0.81
305_T	380_S	0.526	0.81
366_V	369_L	0.526	0.81
93_L	333_L	0.526	0.81
99_V	221_Q	0.525	0.81
316_I	353_V	0.525	0.81
133_I	136_V	0.523	0.81
17_I	381_E	0.522	0.81
332_L	336_L	0.521	0.81
52_V	185_I	0.520	0.81
286_R	403_K	0.520	0.81
243_K	250_F	0.518	0.80
144_A	147_S	0.517	0.80
49_I	371_L	0.517	0.80
389_V	393_V	0.515	0.80
201_F	212_G	0.515	0.80
256_I	260_L	0.515	0.80
17_I	200_A	0.515	0.80
280_M	391_N	0.515	0.80
122_D	125_K	0.514	0.80
49_I	349_S	0.513	0.80
271_S	302_L	0.513	0.80
343_A	350_G	0.513	0.80
81_F	297_G	0.513	0.80
89_L	337_L	0.512	0.80
134_M	140_S	0.511	0.79
375_I	379_M	0.511	0.79
149_N	153_V	0.511	0.79
43_K	134_M	0.511	0.79
87_I	237_V	0.510	0.79
234_V	253_I	0.509	0.79
194_R	198_I	0.509	0.79
132_F	136_V	0.509	0.79
239_G	242_A	0.508	0.79
324_M	332_L	0.508	0.79
152_Q	348_G	0.508	0.79
263_V	272_A	0.508	0.79
252_F	389_V	0.507	0.79
239_G	249_I	0.505	0.79
245_T	393_V	0.505	0.79
34_M	37_L	0.505	0.79
238_L	390_G	0.503	0.78
35_K	210_K	0.503	0.78
219_L	223_I	0.503	0.78
222_L	227_Y	0.502	0.78
304_G	386_T	0.502	0.78
319_A	371_L	0.501	0.78
396_I	405_L	0.501	0.78
193_M	196_A	0.501	0.78
229_T	233_F	0.500	0.78
271_S	276_M	0.500	0.78

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2nwlA	3	0.8972	100	0.1	Contact Map
3nd0A	2	0.8575	65.8	0.958	Contact Map
3zuxA	1	0.7079	49.2	0.962	Contact Map
4eneA	2	0.8879	31	0.966	Contact Map
3klyA	3	0.5164	21.7	0.968	Contact Map
4bwzA	2	0.7944	16.7	0.97	Contact Map
4cz8A	2	0.6402	14.3	0.971	Contact Map
4n7wA	2	0.3645	13.8	0.971	Contact Map
4czbA	2	0.6332	12.5	0.972	Contact Map
3kcuA	3	0.5	10.2	0.973	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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