GREMLIN Database
RRF - Ribosome-recycling factor
UniProt: P0A805 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10335
Length: 185 (180)
Sequences: 3565 (2083)
Seq/√Len: 155.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
72_R96_S3.0551.00
121_A175_L2.9801.00
10_E166_A2.9261.00
161_Q165_D2.6521.00
139_V153_D2.5251.00
20_F124_A2.5171.00
170_K173_A2.4571.00
61_D64_T2.3291.00
20_F24_I2.2501.00
169_K173_A2.2411.00
166_A170_K2.1191.00
158_D162_K2.1181.00
107_E111_K1.9981.00
143_L153_D1.9631.00
83_M90_N1.9521.00
69_V78_V1.9181.00
121_A171_I1.9171.00
9_A135_A1.8741.00
173_A177_D1.8471.00
75_S93_S1.8381.00
36_L102_L1.8211.00
176_A180_A1.8211.00
128_V171_I1.8061.00
66_K97_D1.7541.00
180_A184_Q1.7491.00
7_K10_E1.7301.00
14_D170_K1.7281.00
109_R112_D1.7141.00
136_N160_V1.6761.00
10_E14_D1.6661.00
27_I117_V1.6521.00
41_V48_P1.6351.00
54_L74_M1.6241.00
58_T66_K1.5971.00
74_M77_A1.5921.00
155_R159_D1.5891.00
11_V15_K1.5551.00
64_T101_P1.5531.00
14_D167_A1.5391.00
44_Y49_T1.5371.00
153_D157_Q1.5221.00
133_R137_D1.5001.00
139_V160_V1.4971.00
162_K165_D1.4611.00
43_E48_P1.4611.00
121_A125_R1.4551.00
143_L150_E1.4511.00
79_E93_S1.4481.00
40_I85_S1.4461.00
5_I135_A1.4451.00
176_A179_E1.4221.00
26_K39_G1.4191.00
17_V174_A1.3981.00
167_A170_K1.3891.00
107_E183_M1.3721.00
119_G123_Q1.3591.00
89_L102_L1.3521.00
10_E167_A1.3451.00
44_Y74_M1.3411.00
8_D12_R1.3361.00
21_K174_A1.3291.00
50_P53_Q1.3131.00
148_I153_D1.2891.00
173_A176_A1.2661.00
18_E21_K1.2651.00
136_N140_K1.2551.00
14_D18_E1.2531.00
135_A160_V1.2521.00
24_I121_A1.2521.00
40_I81_A1.2351.00
37_L65_L1.2251.00
113_L182_L1.2201.00
137_D141_A1.2171.00
12_R131_V1.2161.00
23_Q120_E1.2021.00
152_D155_R1.1921.00
141_A145_D1.1911.00
10_E163_L1.1871.00
114_T179_E1.1641.00
27_I120_E1.1621.00
24_I174_A1.1391.00
59_V65_L1.1131.00
136_N157_Q1.1101.00
89_L100_V1.0980.99
117_V175_L1.0950.99
24_I175_L1.0830.99
124_A171_I1.0800.99
44_Y71_D1.0760.99
128_V164_T1.0500.99
71_D74_M1.0480.99
34_P57_V1.0430.99
21_K170_K1.0400.99
5_I9_A1.0370.99
13_M164_T1.0360.99
6_R159_D1.0260.99
16_C131_V1.0140.99
143_L146_K1.0130.99
165_D169_K1.0110.99
105_L113_L1.0070.99
54_L71_D1.0050.99
118_R179_E0.9860.99
139_V156_S0.9760.99
92_N101_P0.9710.99
149_S153_D0.9620.99
120_E123_Q0.9600.99
5_I142_L0.9550.98
177_D180_A0.9520.98
43_E77_A0.9480.98
63_R104_P0.9440.98
94_A99_R0.9330.98
87_L100_V0.9220.98
37_L67_I0.9210.98
60_E66_K0.9200.98
16_C127_A0.9120.98
20_F175_L0.9050.98
19_A23_Q0.8940.98
111_K183_M0.8930.98
117_V182_L0.8850.98
22_T25_S0.8730.97
55_A69_V0.8620.97
142_L148_I0.8580.97
163_L167_A0.8560.97
130_N133_R0.8560.97
19_A22_T0.8530.97
146_K149_S0.8490.97
118_R175_L0.8490.97
128_V168_I0.8430.97
34_P65_L0.8420.97
138_K141_A0.8420.97
15_K131_V0.8410.97
137_D140_K0.8370.97
127_A131_V0.8290.96
49_T54_L0.8290.96
6_R163_L0.8280.96
164_T168_I0.8240.96
114_T183_M0.8210.96
43_E46_G0.8150.96
79_E83_M0.8140.96
9_A163_L0.8130.96
34_P59_V0.8100.96
140_K157_Q0.8100.96
82_I89_L0.8070.96
9_A13_M0.8060.96
7_K11_V0.8000.96
37_L100_V0.7990.95
125_R172_E0.7870.95
59_V62_S0.7850.95
12_R134_D0.7800.95
113_L116_I0.7790.95
109_R113_L0.7780.95
18_E22_T0.7760.95
17_V170_K0.7760.95
59_V64_T0.7710.95
8_D11_V0.7680.94
124_A127_A0.7670.94
13_M167_A0.7650.94
20_F117_V0.7600.94
68_N96_S0.7570.94
6_R10_E0.7540.94
42_V54_L0.7500.94
166_A169_K0.7500.94
142_L147_E0.7480.94
142_L145_D0.7460.94
21_K25_S0.7390.93
169_K172_E0.7380.93
54_L70_F0.7290.93
162_K166_A0.7280.93
116_I120_E0.7280.93
77_A80_K0.7240.92
105_L109_R0.7230.92
6_R160_V0.7190.92
76_P84_A0.7170.92
142_L156_S0.7150.92
26_K120_E0.7050.91
26_K38_D0.6960.91
165_D168_I0.6960.91
17_V128_V0.6950.91
60_E64_T0.6910.91
76_P79_E0.6840.90
6_R156_S0.6830.90
16_C128_V0.6830.90
154_R157_Q0.6810.90
87_L90_N0.6700.89
49_T53_Q0.6660.89
77_A84_A0.6600.89
27_I113_L0.6560.88
24_I117_V0.6560.88
56_S70_F0.6530.88
38_D52_R0.6520.88
58_T68_N0.6500.88
52_R70_F0.6480.88
17_V21_K0.6440.87
23_Q123_Q0.6420.87
20_F174_A0.6410.87
7_K14_D0.6380.87
16_C124_A0.6370.87
150_E154_R0.6340.87
167_A176_A0.6330.86
138_K142_L0.6330.86
40_I51_L0.6250.86
90_N101_P0.6220.85
19_A127_A0.6200.85
80_K84_A0.6180.85
17_V171_I0.6180.85
149_S152_D0.6140.85
66_K99_R0.6130.85
170_K174_A0.6130.85
159_D163_L0.6120.85
9_A131_V0.6120.85
113_L117_V0.6100.84
125_R168_I0.6080.84
17_V167_A0.6080.84
67_I83_M0.6050.84
35_S65_L0.6040.84
114_T175_L0.6010.83
163_L166_A0.5980.83
20_F171_I0.5970.83
154_R158_D0.5970.83
159_D162_K0.5910.82
42_V74_M0.5890.82
75_S94_A0.5880.82
16_C19_A0.5840.82
101_P104_P0.5830.82
11_V14_D0.5820.82
19_A37_L0.5800.81
133_R136_N0.5780.81
70_F74_M0.5700.80
116_I119_G0.5690.80
94_A97_D0.5680.80
89_L101_P0.5660.80
73_S76_P0.5660.80
21_K177_D0.5620.79
170_K177_D0.5590.79
14_D17_V0.5590.79
114_T182_L0.5500.78
52_R71_D0.5380.76
73_S77_A0.5340.76
38_D70_F0.5330.76
14_D163_L0.5310.75
29_T33_S0.5280.75
112_D119_G0.5270.75
76_P92_N0.5260.75
32_A102_L0.5260.75
90_N100_V0.5250.75
25_S90_N0.5250.75
121_A172_E0.5250.75
37_L87_L0.5240.74
56_S74_M0.5220.74
112_D116_I0.5200.74
118_R136_N0.5190.74
49_T71_D0.5180.74
63_R184_Q0.5170.73
67_I78_V0.5120.73
79_E92_N0.5110.73
158_D161_Q0.5110.73
145_D166_A0.5100.72
119_G180_A0.5100.72
75_S96_S0.5070.72
35_S38_D0.5050.72
29_T63_R0.5050.72
69_V96_S0.5040.72
125_R175_L0.5040.72
44_Y48_P0.5030.71
137_D182_L0.5020.71
43_E49_T0.5020.71
121_A124_A0.5010.71
46_G178_K0.5010.71
38_D57_V0.5010.71
136_N139_V0.5010.71
174_A177_D0.5000.71
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1is1A 1 1 100 -0.022 Contact Map
1dd5A 1 0.9946 100 -0.022 Contact Map
4kddA 1 0.9946 100 -0.021 Contact Map
1iseA 1 0.9946 100 -0.021 Contact Map
1eh1A 1 0.9946 100 -0.019 Contact Map
4gfqA 1 1 100 -0.009 Contact Map
1ge9A 1 0.9784 100 0.023 Contact Map
3lf9A 1 0.6108 100 0.484 Contact Map
1wihA 1 0.4432 100 0.499 Contact Map
3lhpS 1 0.627 99.9 0.532 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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