GREMLIN Database
RS8 - 30S ribosomal protein S8
UniProt: P0A7W7 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10907
Length: 130 (127)
Sequences: 2584 (1229)
Seq/√Len: 109.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
41_K48_D3.6481.00
108_K119_A3.3561.00
89_K120_G3.3321.00
12_T15_R3.3301.00
35_A38_N2.9321.00
38_N42_E2.8571.00
10_M37_A2.8081.00
26_T60_E2.7461.00
42_E115_A2.7421.00
113_D117_R2.4271.00
9_D13_R2.3561.00
115_A119_A2.3511.00
18_Q70_A2.2781.00
7_I36_I2.0431.00
11_L127_C1.9961.00
34_V51_V1.9231.00
37_A61_L1.9171.00
6_P33_K1.8061.00
24_A60_E1.7201.00
26_T58_E1.7151.00
46_I49_F1.7041.00
17_G25_V1.6891.00
52_E60_E1.6811.00
53_G57_P1.6471.00
5_D77_R1.6111.00
40_L129_V1.5361.00
39_V110_V1.5171.00
88_R91_E1.5161.00
115_A118_Q1.5081.00
10_M27_M1.4751.00
76_Q128_Y1.4751.00
32_L126_I1.4721.00
41_K46_I1.4501.00
30_S33_K1.3921.00
92_L113_D1.3721.00
36_I110_V1.3651.00
38_N49_F1.3170.99
27_M59_L1.3130.99
7_I32_L1.2960.99
50_K60_E1.2810.99
66_F69_K1.2740.99
102_A128_Y1.2480.99
29_S34_V1.2210.99
44_G64_K1.1970.99
50_K62_T1.1850.99
87_K92_L1.1830.99
66_F70_A1.1640.99
95_V102_A1.1490.99
45_F101_I1.1280.98
6_P30_S1.1260.98
24_A62_T1.0820.98
87_K104_V1.0620.98
29_S57_P1.0490.97
83_L128_Y1.0460.97
38_N41_K1.0430.97
28_P33_K1.0360.97
74_S96_M1.0360.97
21_N68_G1.0160.97
55_T58_E1.0150.97
92_L104_V1.0140.97
34_V38_N1.0100.97
17_G20_A0.9940.96
84_R124_E0.9850.96
105_S109_G0.9720.96
39_V103_V0.9710.96
51_V57_P0.9610.96
34_V57_P0.9530.95
74_S128_Y0.9440.95
103_V127_C0.9420.95
106_T111_M0.9420.95
78_V85_I0.9410.95
125_I128_Y0.9410.95
41_K49_F0.9390.95
29_S51_V0.9370.95
27_M61_L0.9330.95
45_F99_L0.9320.95
34_V59_L0.9290.95
77_R84_R0.9180.94
10_M36_I0.8800.93
36_I127_C0.8680.92
8_A33_K0.8650.92
54_D58_E0.8550.92
110_V126_I0.8540.92
47_E62_T0.8390.91
10_M33_K0.8340.91
48_D62_T0.8300.91
78_V125_I0.8290.91
65_Y70_A0.8230.90
87_K125_I0.8080.90
43_E115_A0.8070.89
32_L110_V0.8070.89
54_D57_P0.7970.89
87_K91_E0.7930.89
111_M115_A0.7910.89
102_A113_D0.7680.87
93_P102_A0.7540.86
94_K113_D0.7540.86
108_K111_M0.7520.86
14_I72_V0.7520.86
21_N70_A0.7510.86
31_K34_V0.7410.85
86_Y124_E0.7230.84
69_K73_E0.7180.83
92_L125_I0.7180.83
34_V41_K0.7150.83
98_G113_D0.7150.83
14_I75_I0.7100.82
93_P128_Y0.7020.82
18_Q66_F0.6960.81
27_M33_K0.6930.81
52_E58_E0.6890.81
64_K72_V0.6880.80
78_V128_Y0.6780.80
95_V98_G0.6730.79
11_L15_R0.6710.79
36_I103_V0.6590.78
65_Y72_V0.6540.77
15_R127_C0.6520.77
111_M119_A0.6460.76
30_S45_F0.6450.76
39_V127_C0.6440.76
108_K121_L0.6360.75
106_T109_G0.6340.75
18_Q71_V0.6300.74
40_L101_I0.6290.74
26_T52_E0.6270.74
51_V59_L0.6220.73
53_G56_K0.6190.73
23_A47_E0.6180.73
111_M121_L0.6160.73
35_A42_E0.6080.72
6_P10_M0.6080.72
105_S110_V0.6060.72
18_Q75_I0.6040.71
95_V128_Y0.5980.71
37_A40_L0.5970.70
101_I129_V0.5960.70
13_R28_P0.5960.70
12_T75_I0.5910.70
49_F61_L0.5910.70
32_L35_A0.5900.69
4_Q107_S0.5900.69
37_A59_L0.5880.69
18_Q72_V0.5860.69
46_I61_L0.5850.69
44_G98_G0.5820.68
34_V49_F0.5770.68
10_M85_I0.5700.67
4_Q33_K0.5700.67
82_G124_E0.5680.67
52_E55_T0.5670.66
7_I23_A0.5630.66
110_V119_A0.5590.65
104_V125_I0.5580.65
90_D107_S0.5570.65
14_I61_L0.5510.64
46_I103_V0.5500.64
79_S84_R0.5470.64
96_M114_R0.5470.64
18_Q80_R0.5460.64
109_G122_G0.5450.63
37_A51_V0.5380.62
36_I39_V0.5340.62
107_S121_L0.5310.61
47_E60_E0.5290.61
35_A50_K0.5270.61
68_G83_L0.5230.60
43_E112_T0.5230.60
24_A47_E0.5230.60
20_A37_A0.5210.60
31_K57_P0.5200.60
4_Q80_R0.5170.59
91_E116_A0.5170.59
66_F71_V0.5160.59
88_R107_S0.5140.59
4_Q8_A0.5140.59
23_A66_F0.5130.59
71_V99_L0.5120.59
33_K112_T0.5100.58
10_M43_E0.5100.58
4_Q96_M0.5090.58
106_T122_G0.5050.58
5_D8_A0.5050.58
23_A118_Q0.5040.57
116_A121_L0.5030.57
13_R22_K0.5030.57
10_M25_V0.5010.57
74_S127_C0.5010.57
3_M26_T0.5000.57
39_V101_I0.5000.57
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4pdbA 1 0.9769 100 0.1 Contact Map
1s03H 1 0.9769 100 0.112 Contact Map
4rb5H 1 0.9846 100 0.115 Contact Map
1seiA 2 0.9923 100 0.117 Contact Map
3rf2A 1 0.9769 100 0.137 Contact Map
3bbnH 1 0.9923 100 0.144 Contact Map
1i6uA 1 0.9385 100 0.228 Contact Map
4bpeH 1 0.9308 100 0.25 Contact Map
4ujpX 1 0.9308 100 0.278 Contact Map
3qd7X 1 0.5 24.3 0.937 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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