GREMLIN Database
RS3 - 30S ribosomal protein S3
UniProt: P0A7V3 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10902
Length: 233 (210)
Sequences: 2528 (1162)
Seq/√Len: 80.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
53_S112_D5.5151.00
116_V202_I4.5841.00
190_H195_V3.9921.00
188_E195_V3.8911.00
46_E90_V3.5751.00
111_L146_A3.3431.00
83_D86_K2.9691.00
44_T114_K2.8281.00
67_T102_N2.8231.00
141_A149_I2.7121.00
125_E189_A2.6121.00
136_R140_N2.5951.00
128_V133_A2.4141.00
203_F206_E2.3901.00
152_E165_T2.2581.00
113_A183_D2.1861.00
70_T76_V2.1471.00
114_K118_D2.0421.00
172_R203_F1.9911.00
16_K19_N1.9171.00
120_I151_V1.9101.00
47_L76_V1.8901.00
19_N54_R1.8621.00
124_L130_F1.8501.00
118_D187_S1.8131.00
8_N19_N1.7641.00
21_T56_V1.7361.00
28_E31_D1.7351.00
54_R69_H1.7011.00
180_A203_F1.6951.00
8_N16_K1.6681.00
69_H104_A1.6471.00
44_T118_D1.6171.00
120_I133_A1.6101.00
10_I14_I1.5961.00
16_K181_D1.5881.00
114_K186_T1.5871.00
114_K187_S1.5861.00
34_D38_K1.5821.00
29_F33_L1.5811.00
114_K185_N1.5811.00
35_S97_V1.5611.00
147_K172_R1.5450.99
152_E167_W1.5360.99
38_K94_I1.5230.99
181_D204_K1.4780.99
17_P21_T1.4290.99
117_A187_S1.4220.99
169_R173_V1.4200.99
134_M168_Y1.3980.99
111_L141_A1.3840.99
34_D37_F1.3820.99
21_T58_E1.3780.99
47_L87_L1.3760.99
42_Y90_V1.3740.99
120_I137_A1.3710.99
86_K89_K1.3610.99
169_R172_R1.3560.99
15_V207_I1.3520.99
130_F157_L1.3230.98
154_S165_T1.3150.98
85_E89_K1.3140.98
10_I178_L1.3040.98
124_L196_I1.2820.98
153_V196_I1.2530.98
18_W21_T1.2400.97
50_A75_I1.2330.97
25_N28_E1.2210.97
29_F34_D1.2200.97
117_A200_V1.2140.97
138_V151_V1.2130.97
119_S122_S1.2000.97
64_I97_V1.1950.97
117_A198_V1.1950.97
43_L52_V1.1930.97
167_W172_R1.1850.97
51_S70_T1.1830.97
135_K158_G1.1830.97
86_K90_V1.1780.97
74_G105_E1.1740.97
78_G81_G1.1720.96
138_V149_I1.1710.96
58_E65_R1.1640.96
89_K92_A1.1570.96
63_S98_P1.1570.96
33_L37_F1.1470.96
150_K175_L1.1400.96
67_T104_A1.1290.96
10_I15_V1.1290.96
80_K136_R1.1250.96
30_A34_D1.1060.95
89_K93_D1.1020.95
116_V137_A1.1020.95
38_K41_Q1.1010.95
14_I178_L1.0980.95
8_N12_L1.0950.95
6_H10_I1.0950.95
134_M153_V1.0670.94
46_E86_K1.0650.94
174_P180_A1.0620.94
92_A98_P1.0570.94
37_F41_Q1.0440.93
44_T48_A1.0430.93
91_V99_A1.0400.93
118_D122_S1.0210.93
73_P77_I1.0200.93
5_V102_N1.0130.92
121_T187_S1.0060.92
43_L55_I0.9890.91
122_S126_R0.9840.91
154_S162_I0.9830.91
95_A99_A0.9800.91
54_R112_D0.9790.91
43_L47_L0.9750.91
121_T198_V0.9740.91
15_V19_N0.9640.90
116_V141_A0.9630.90
9_G13_G0.9560.90
108_K144_L0.9520.90
151_V168_Y0.9480.90
139_Q170_E0.9280.89
129_M158_G0.9250.88
130_F166_E0.9220.88
157_L196_I0.9200.88
84_V95_A0.9200.88
52_V68_I0.9180.88
76_V103_I0.9150.88
16_K204_K0.9100.88
66_V101_I0.9000.87
82_E86_K0.8810.86
124_L166_E0.8740.85
63_S100_Q0.8670.85
77_I81_G0.8650.85
157_L193_Y0.8610.84
7_P11_R0.8590.84
5_V10_I0.8570.84
50_A70_T0.8510.84
141_A202_I0.8500.84
47_L52_V0.8470.84
36_D40_R0.8360.83
80_K140_N0.8340.83
181_D207_I0.8310.82
119_S123_Q0.8240.82
174_P203_F0.8190.81
173_V203_F0.7990.80
56_V69_H0.7980.80
42_Y91_V0.7940.79
74_G77_I0.7840.78
111_L202_I0.7810.78
51_S71_A0.7800.78
36_D57_I0.7790.78
84_V103_I0.7780.78
59_R113_A0.7770.78
48_A125_E0.7740.78
134_M185_N0.7710.77
183_D204_K0.7620.77
92_A100_Q0.7580.76
4_K191_T0.7540.76
24_A32_N0.7480.75
41_Q45_K0.7460.75
140_N143_R0.7460.75
43_L66_V0.7420.75
184_Y201_W0.7420.75
74_G78_G0.7420.75
180_A205_G0.7410.74
74_G81_G0.7390.74
35_S38_K0.7380.74
111_L204_K0.7370.74
73_P78_G0.7370.74
22_W36_D0.7340.74
130_F192_T0.7310.73
119_S173_V0.7290.73
74_G79_K0.7290.73
151_V167_W0.7240.73
45_K48_A0.7230.73
194_G197_G0.7210.72
36_D127_R0.7180.72
40_R57_I0.7130.72
81_G105_E0.7110.71
156_R193_Y0.7090.71
72_R91_V0.7040.71
138_V168_Y0.6990.70
147_K205_G0.6900.69
12_L17_P0.6900.69
42_Y46_E0.6850.69
28_E32_N0.6820.68
40_R55_I0.6820.68
138_V170_E0.6810.68
142_M146_A0.6810.68
108_K111_L0.6760.68
139_Q143_R0.6740.67
176_H203_F0.6730.67
17_P202_I0.6730.67
47_L68_I0.6730.67
130_F158_G0.6700.67
162_I166_E0.6680.67
134_M151_V0.6640.66
35_S95_A0.6620.66
56_V67_T0.6590.66
110_E140_N0.6540.65
106_V115_L0.6540.65
147_K203_F0.6530.65
64_I136_R0.6480.64
167_W173_V0.6390.63
109_P145_G0.6380.63
138_V203_F0.6370.63
164_R179_R0.6340.63
60_P136_R0.6300.62
19_N56_V0.6250.62
3_Q143_R0.6230.61
28_E80_K0.6190.61
146_A157_L0.6180.61
162_I165_T0.6170.61
124_L137_A0.6160.60
65_R126_R0.6160.60
156_R161_E0.6160.60
6_H172_R0.6120.60
25_N101_I0.6120.60
135_K163_A0.6110.60
31_D34_D0.6110.60
48_A55_I0.6100.60
65_R207_I0.6080.59
136_R139_Q0.6080.59
110_E144_L0.6080.59
45_K94_I0.6070.59
1_M4_K0.6060.59
79_K83_D0.6040.59
127_R189_A0.6030.59
126_R162_I0.6010.59
151_V198_V0.6010.59
45_K93_D0.6010.59
25_N98_P0.6000.58
175_L201_W0.5990.58
124_L131_R0.5990.58
12_L169_R0.5970.58
131_R166_E0.5950.58
72_R209_G0.5940.58
72_R110_E0.5940.58
193_Y196_I0.5930.58
70_T157_L0.5930.58
121_T125_E0.5930.58
128_V132_R0.5930.58
30_A37_F0.5920.57
27_K89_K0.5900.57
32_N35_S0.5890.57
72_R78_G0.5890.57
1_M7_P0.5880.57
134_M182_I0.5880.57
25_N173_V0.5860.57
141_A146_A0.5840.56
110_E119_S0.5830.56
153_V158_G0.5790.56
148_G155_G0.5780.56
56_V83_D0.5780.56
33_L40_R0.5750.55
90_V198_V0.5730.55
1_M11_R0.5710.55
127_R164_R0.5710.55
58_E67_T0.5690.54
175_L191_T0.5690.54
154_S199_K0.5680.54
176_H180_A0.5680.54
60_P88_R0.5640.54
161_E200_V0.5630.54
174_P199_K0.5630.54
47_L50_A0.5610.53
184_Y199_K0.5610.53
66_V96_G0.5590.53
135_K175_L0.5590.53
110_E116_V0.5590.53
4_K11_R0.5540.53
17_P210_G0.5500.52
40_R180_A0.5500.52
179_R205_G0.5460.51
49_K108_K0.5450.51
47_L150_K0.5450.51
57_I117_A0.5430.51
52_V70_T0.5420.51
162_I167_W0.5420.51
64_I95_A0.5390.51
152_E169_R0.5380.50
39_V100_Q0.5340.50
12_L15_V0.5330.50
23_F37_F0.5330.50
120_I200_V0.5290.49
62_K210_G0.5280.49
65_R102_N0.5280.49
4_K7_P0.5270.49
51_S106_V0.5270.49
111_L116_V0.5250.49
82_E88_R0.5220.48
141_A204_K0.5210.48
49_K83_D0.5200.48
146_A168_Y0.5200.48
156_R201_W0.5200.48
29_F37_F0.5200.48
60_P63_S0.5190.48
43_L68_I0.5170.48
18_W107_R0.5170.48
150_K156_R0.5160.48
61_A100_Q0.5150.47
163_A196_I0.5140.47
43_L132_R0.5110.47
32_N211_M0.5070.46
129_M132_R0.5060.46
121_T189_A0.5060.46
83_D136_R0.5050.46
139_Q209_G0.5040.46
70_T105_E0.5030.46
177_T180_A0.5020.46
112_D183_D0.5020.46
111_L144_L0.5020.46
61_A80_K0.5010.46
161_E164_R0.5000.46
98_P104_A0.5000.46
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4rb5C 1 0.8841 100 0.033 Contact Map
4kiyC 1 0.8841 100 0.033 Contact Map
3bbnC 1 0.8841 100 0.067 Contact Map
4tp8C 1 0.8841 100 0.072 Contact Map
3j20C 1 0.7854 100 0.259 Contact Map
4ujpE 1 0.897 100 0.287 Contact Map
3zeyX 1 0.8326 100 0.299 Contact Map
4w23D 1 0.9013 100 0.299 Contact Map
3j7aD 1 0.6438 100 0.305 Contact Map
4bpeC 1 0.8927 100 0.318 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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