GREMLIN Database
RS19 - 30S ribosomal protein S19
UniProt: P0A7U3 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10918
Length: 92 (88)
Sequences: 1987 (763)
Seq/√Len: 81.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
12_D37_R4.5341.00
23_V47_L4.1331.00
30_P50_A3.4441.00
22_A47_L3.2561.00
53_N56_Q2.8501.00
33_T71_L2.5341.00
39_T70_K2.3921.00
11_I41_F2.1611.00
49_I62_V2.1471.00
34_W57_H2.0811.00
20_E43_N1.9321.00
58_V75_A1.7471.00
84_A87_K1.7241.00
10_F14_H1.7001.00
72_G77_T1.6621.00
16_L20_E1.6151.00
22_A27_D1.5931.00
44_M49_I1.5771.00
21_K25_S1.4760.99
51_V62_V1.4740.99
10_F38_S1.4730.99
51_V60_V1.4570.99
35_S38_S1.3670.99
53_N58_V1.3290.98
53_N75_A1.3230.98
21_K24_E1.3200.98
55_R79_T1.2800.98
30_P56_Q1.2450.98
48_T59_P1.1720.97
69_H73_E1.0870.95
41_F44_M1.0610.94
41_F65_E1.0280.93
17_K21_K1.0220.93
4_S9_P1.0210.93
16_L41_F1.0200.93
4_S7_K0.9980.92
20_E24_E0.9940.92
56_Q79_T0.9930.92
10_F35_S0.9890.92
43_N64_D0.9650.91
41_F45_I0.9550.90
50_A59_P0.9550.90
32_R56_Q0.9500.90
7_K11_I0.9470.90
52_H65_E0.9410.90
36_R54_G0.9400.89
68_G73_E0.9340.89
49_I59_P0.9330.89
15_L38_S0.9230.89
48_T60_V0.9230.89
4_S8_G0.9220.89
23_V27_D0.9040.88
14_H37_R0.8900.87
56_Q59_P0.8800.86
69_H74_F0.8680.85
80_Y85_A0.8480.84
5_L41_F0.8360.83
28_K48_T0.8270.83
52_H66_M0.8160.82
19_V49_I0.8070.81
8_G64_D0.7980.80
44_M67_V0.7920.80
24_E65_E0.7690.78
57_H75_A0.7690.78
2_P7_K0.7670.78
84_A88_K0.7650.77
28_K47_L0.7580.77
15_L19_V0.7360.75
15_L33_T0.7350.74
16_L19_V0.7330.74
18_K31_L0.7300.74
12_D35_S0.7220.73
2_P37_R0.7180.73
15_L71_L0.7050.71
78_R85_A0.7040.71
1_M4_S0.6920.70
16_L43_N0.6860.69
27_D61_F0.6830.69
7_K10_F0.6790.69
13_L17_K0.6730.68
31_L49_I0.6720.68
12_D15_L0.6700.67
69_H72_G0.6690.67
27_D47_L0.6680.67
19_V47_L0.6570.66
19_V23_V0.6560.66
21_K29_K0.6550.66
23_V26_G0.6540.66
65_E85_A0.6370.64
44_M55_R0.6360.63
21_K87_K0.6310.63
53_N57_H0.6270.62
14_H35_S0.6270.62
32_R39_T0.6260.62
3_R8_G0.6240.62
43_N57_H0.6240.62
55_R58_V0.6160.61
55_R88_K0.6130.61
22_A44_M0.6080.60
4_S72_G0.6080.60
49_I71_L0.6030.59
8_G30_P0.6020.59
2_P70_K0.5850.57
8_G12_D0.5820.57
10_F13_L0.5780.56
16_L21_K0.5740.56
13_L25_S0.5730.56
69_H75_A0.5710.55
79_T82_G0.5660.55
30_P59_P0.5660.55
53_N88_K0.5620.54
3_R36_R0.5610.54
16_L23_V0.5570.53
48_T61_F0.5550.53
51_V84_A0.5520.53
33_T42_P0.5450.52
3_R68_G0.5450.52
31_L47_L0.5370.51
15_L18_K0.5350.51
85_A88_K0.5340.50
2_P39_T0.5250.49
81_R84_A0.5240.49
46_G52_H0.5200.49
7_K70_K0.5200.49
41_F53_N0.5200.49
17_K20_E0.5100.47
37_R70_K0.5070.47
24_E79_T0.5070.47
15_L35_S0.5060.47
29_K59_P0.5060.47
45_I78_R0.5050.47
43_N65_E0.5000.46
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3bbnS 1 1 100 0.041 Contact Map
3a1pB 1 0.913 100 0.047 Contact Map
4kiyS 1 0.8587 100 0.049 Contact Map
3j20T 1 0.913 100 0.114 Contact Map
4tp8S 1 0.8587 100 0.137 Contact Map
4ujpQ 1 0.9022 100 0.15 Contact Map
3zeyI 1 1 100 0.161 Contact Map
4bpeS 1 0.9022 100 0.17 Contact Map
3j7aX 1 0.7391 100 0.172 Contact Map
3j38P 1 0.8696 100 0.198 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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