GREMLIN Database
RS16 - 30S ribosomal protein S16
UniProt: P0A7T3 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10915
Length: 82 (75)
Sequences: 2399 (1146)
Seq/√Len: 132.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
59_H63_Q3.3041.00
56_R59_H3.1951.00
36_V57_I2.4851.00
4_I21_V2.1511.00
40_N43_A2.0741.00
34_E56_R1.9351.00
43_A49_G1.8991.00
54_L58_A1.8841.00
7_A35_R1.8181.00
21_V36_V1.8101.00
67_I75_I1.7721.00
22_A26_N1.6771.00
38_F51_R1.6151.00
22_A32_F1.5741.00
3_T68_S1.4731.00
11_A14_R1.4681.00
45_E48_E1.4031.00
57_I75_I1.3791.00
21_V33_I1.3591.00
3_T24_S1.3521.00
18_Q35_R1.3421.00
61_V67_I1.3061.00
69_D72_A1.3061.00
26_N31_R1.2541.00
52_L57_I1.2511.00
2_V33_I1.2501.00
53_D56_R1.2381.00
9_H18_Q1.2371.00
19_V52_L1.2101.00
58_A62_G1.2010.99
7_A32_F1.1680.99
73_A77_E1.1650.99
59_H62_G1.1370.99
32_F35_R1.1360.99
4_I65_A1.1360.99
19_V71_V1.1350.99
14_R42_I1.1330.99
70_R73_A1.1190.99
16_F38_F1.1090.99
2_V21_V1.0690.99
72_A76_K1.0480.99
15_P42_I1.0380.99
56_R63_Q1.0370.98
27_A32_F0.9970.98
45_E49_G0.9660.98
8_R15_P0.9560.97
73_A76_K0.9490.97
35_R38_F0.9440.97
48_E51_R0.9430.97
4_I71_V0.9210.97
40_N49_G0.9100.97
23_D33_I0.8790.96
16_F40_N0.8760.96
61_V75_I0.8710.96
6_L68_S0.8710.96
9_H35_R0.8630.95
16_F42_I0.8510.95
6_L19_V0.8430.95
39_F70_R0.8270.94
57_I67_I0.8190.94
58_A61_V0.8030.93
24_S68_S0.7880.93
2_V23_D0.7660.91
43_A48_E0.7520.91
27_A30_G0.7430.90
27_A31_R0.7390.90
54_L75_I0.7300.89
58_A75_I0.7300.89
52_L74_L0.7220.89
54_L78_V0.7190.89
6_L74_L0.7140.88
26_N32_F0.6910.87
71_V74_L0.6840.86
38_F49_G0.6840.86
9_H16_F0.6790.86
42_I48_E0.6650.85
7_A29_N0.6610.84
17_Y77_E0.6570.84
60_W63_Q0.6500.83
18_Q39_F0.6400.82
2_V25_R0.6400.82
3_T66_T0.6300.81
61_V66_T0.6230.81
44_S48_E0.6150.80
22_A31_R0.6100.79
70_R77_E0.6070.79
42_I49_G0.6000.78
67_I71_V0.6000.78
55_D58_A0.5960.78
49_G77_E0.5880.77
58_A78_V0.5810.76
53_D57_I0.5730.75
45_E50_T0.5710.75
20_V32_F0.5660.74
22_A27_A0.5610.73
50_T78_V0.5540.72
50_T74_L0.5440.71
34_E60_W0.5420.71
17_Y41_P0.5400.70
34_E59_H0.5350.70
52_L75_I0.5310.69
50_T77_E0.5240.68
26_N30_G0.5220.68
57_I61_V0.5220.68
4_I67_I0.5210.68
2_V60_W0.5180.67
22_A30_G0.5130.67
39_F74_L0.5130.67
21_V65_A0.5050.65
29_N55_D0.5010.65
58_A76_K0.5010.65
29_N34_E0.5000.65
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4tp8P 1 1 100 0.027 Contact Map
5aj3P 1 1 100 0.077 Contact Map
4juwP 1 0.9878 100 0.077 Contact Map
3bbnP 1 0.9512 100 0.08 Contact Map
3bn0A 1 0.8902 100 0.085 Contact Map
3ks9A 2 0.5854 14.9 0.921 Contact Map
2b78A 1 0.9878 13.3 0.923 Contact Map
4ms4B 1 0.6829 13.2 0.923 Contact Map
4ms4A 1 0.7439 10.5 0.926 Contact Map
2cs4A 1 0.5 10.3 0.926 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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