GREMLIN Database
RS10 - 30S ribosomal protein S10
UniProt: P0A7R5 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10909
Length: 103 (99)
Sequences: 810 (355)
Seq/√Len: 35.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
50_T64_Q5.2461.00
53_I61_A4.5461.00
32_T83_T4.3511.00
7_R75_D4.1421.00
47_E69_T3.6571.00
50_T62_R3.1361.00
54_S58_N2.9741.00
52_L55_P2.4241.00
12_A18_I2.0750.99
54_S57_V2.0390.99
46_K68_R1.8780.97
12_A91_D1.6300.94
75_D90_L1.6110.94
52_L60_D1.5610.93
52_L56_H1.5460.92
53_I65_Y1.5440.92
28_T31_R1.5090.92
18_I22_T1.4770.91
23_A27_E1.4610.90
57_V60_D1.4580.90
61_A65_Y1.4560.90
11_K99_Q1.4010.88
5_R37_R1.3950.88
5_R18_I1.3420.86
55_P58_N1.3360.86
27_E60_D1.3030.84
35_Q78_E1.2660.82
93_A98_V1.2630.82
22_T37_R1.2080.79
56_H62_R1.2010.79
15_H19_D1.1810.78
47_E67_I1.1480.76
48_R64_Q1.1020.73
52_L57_V1.0960.72
47_E50_T1.0730.70
28_T86_A1.0400.68
24_E91_D1.0270.67
16_R19_D1.0000.65
52_L62_R0.9970.65
47_E64_Q0.9770.63
10_L18_I0.9640.62
19_D72_R0.9590.62
8_I30_K0.9570.62
45_R71_L0.9370.60
52_L69_T0.9250.59
5_R52_L0.9240.59
22_T26_V0.9070.57
28_T88_M0.9060.57
37_R74_V0.9000.57
50_T56_H0.8960.56
19_D41_P0.8900.56
26_V74_V0.8870.56
56_H68_R0.8840.55
37_R93_A0.8830.55
98_V101_S0.8780.55
14_D19_D0.8670.54
17_L21_A0.8670.54
6_I9_R0.8610.53
29_A34_A0.8590.53
40_I77_V0.8580.53
29_A73_L0.8530.53
37_R77_V0.8520.53
71_L74_V0.8400.52
63_D81_E0.8350.51
24_E89_R0.8300.51
48_R51_V0.8270.50
49_F69_T0.8270.50
33_G83_T0.8260.50
29_A76_I0.8020.48
18_I21_A0.7950.48
17_L35_Q0.7860.47
60_D64_Q0.7860.47
74_V85_D0.7690.45
32_T80_T0.7660.45
27_E79_P0.7590.45
30_K56_H0.7570.44
82_K86_A0.7370.43
53_I63_D0.7310.42
47_E71_L0.7240.42
66_E78_E0.7240.42
88_M97_D0.7210.41
42_L73_L0.7150.41
40_I73_L0.7070.40
3_N58_N0.7020.40
47_E51_V0.7020.40
27_E31_R0.7010.40
28_T90_L0.6980.39
9_R45_R0.6960.39
35_Q77_V0.6830.38
25_I74_V0.6790.38
14_D41_P0.6760.38
42_L93_A0.6750.38
69_T94_A0.6720.37
24_E94_A0.6590.36
13_F100_I0.6500.36
44_T93_A0.6430.35
41_P72_R0.6420.35
51_V55_P0.6400.35
40_I89_R0.6360.34
49_F58_N0.6320.34
27_E34_A0.6300.34
6_I54_S0.6290.34
12_A67_I0.6230.33
24_E82_K0.6230.33
6_I36_V0.6170.33
18_I63_D0.6130.33
34_A83_T0.6100.32
44_T70_H0.6020.32
53_I56_H0.6010.32
90_L101_S0.5960.31
45_R58_N0.5940.31
29_A74_V0.5890.31
41_P85_D0.5790.30
5_R75_D0.5750.30
55_P88_M0.5730.30
12_A16_R0.5710.30
21_A87_L0.5680.29
80_T85_D0.5640.29
88_M98_V0.5600.29
73_L92_L0.5570.29
13_F45_R0.5560.29
18_I91_D0.5560.29
20_Q30_K0.5520.28
30_K35_Q0.5490.28
58_N61_A0.5430.28
81_E99_Q0.5430.28
3_N80_T0.5420.28
42_L99_Q0.5400.27
25_I83_T0.5400.27
3_N78_E0.5340.27
60_D70_H0.5310.27
37_R67_I0.5300.27
11_K83_T0.5260.26
76_I100_I0.5260.26
21_A73_L0.5240.26
95_G101_S0.5200.26
11_K62_R0.5180.26
35_Q81_E0.5180.26
32_T87_L0.5140.26
67_I89_R0.5130.26
60_D95_G0.5050.25
84_V88_M0.5040.25
52_L61_A0.5030.25
22_T73_L0.5010.25
54_S91_D0.5010.25
40_I71_L0.5010.25
9_R42_L0.5010.25
32_T61_A0.5000.25
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3bbnJ 1 0.9612 100 0.233 Contact Map
3w1yC 1 0.8738 100 0.241 Contact Map
3zeyQ 1 0.9903 100 0.269 Contact Map
3j20L 1 0.9709 100 0.273 Contact Map
4rb5J 1 0.9417 100 0.273 Contact Map
4w23U 1 0.9806 100 0.275 Contact Map
3j7aN 1 0.9223 100 0.275 Contact Map
4bpeJ 1 0.9903 100 0.279 Contact Map
3j60U 1 0.9903 100 0.28 Contact Map
4ujpV 1 0.9903 100 0.281 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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