GREMLIN Database
RL32 - 50S ribosomal protein L32
UniProt: P0A7N4 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10890
Length: 57 (55)
Sequences: 305 (110)
Seq/√Len: 14.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
31_D44_T3.7001.00
11_S15_M2.5250.94
9_T14_G2.2440.89
43_I55_I2.2430.89
8_P15_M1.9390.81
12_K18_S1.8750.78
43_I54_V1.8050.75
10_R16_R1.8040.75
37_K46_D1.7430.73
25_V39_L1.5690.64
34_S44_T1.5320.62
28_L37_K1.5180.62
5_Q14_G1.4600.59
48_Y53_K1.4430.58
10_R32_K1.4120.56
24_A27_S1.3390.52
53_K56_A1.3170.51
30_V37_K1.2630.48
28_L39_L1.2590.47
32_K39_L1.2200.45
27_S46_D1.1770.43
38_H44_T1.1570.42
35_G42_H1.1410.41
7_K21_A1.1180.40
18_S29_S1.1000.39
39_L46_D1.0950.38
31_D46_D1.0760.37
16_R46_D1.0720.37
10_R25_V1.0420.36
10_R31_D1.0330.35
15_M18_S1.0240.35
6_N12_K0.9940.33
27_S39_L0.9520.31
8_P12_K0.9300.30
36_E44_T0.8760.28
9_T16_R0.8730.28
7_K30_V0.8290.26
33_T50_R0.8200.25
6_N14_G0.8140.25
28_L32_K0.8090.25
12_K15_M0.8030.25
39_L42_H0.7810.24
40_R50_R0.7760.23
45_A54_V0.7740.23
21_A27_S0.7720.23
23_T32_K0.7680.23
15_M49_Y0.7640.23
33_T48_Y0.7460.22
43_I46_D0.7370.22
7_K14_G0.7330.22
24_A37_K0.7310.22
6_N53_K0.7190.21
16_R21_A0.7140.21
34_S42_H0.7130.21
20_D42_H0.6970.20
21_A56_A0.6950.20
28_L56_A0.6880.20
23_T39_L0.6850.20
43_I56_A0.6690.19
35_G52_R0.6350.18
33_T56_A0.6320.18
8_P43_I0.6200.18
16_R27_S0.6130.18
42_H52_R0.6110.17
29_S38_H0.5970.17
48_Y52_R0.5910.17
23_T29_S0.5860.17
50_R55_I0.5720.16
35_G54_V0.5570.16
23_T55_I0.5560.16
23_T56_A0.5510.16
19_H22_L0.5450.15
5_Q16_R0.5390.15
8_P25_V0.5370.15
45_A55_I0.5350.15
10_R40_R0.5300.15
29_S36_E0.5240.15
10_R30_V0.5240.15
30_V48_Y0.5180.15
7_K16_R0.5130.15
29_S48_Y0.5080.14
5_Q17_R0.5000.14
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3j3w0 1 0.9474 99.7 0.421 Contact Map
2zjrZ 1 0.9474 99.7 0.423 Contact Map
4tp90 1 0.9649 99.7 0.428 Contact Map
4rb65 1 0.9825 99.7 0.43 Contact Map
4ce45 1 0.807 99.5 0.501 Contact Map
1vw4W 1 0.9649 99.4 0.519 Contact Map
3j7y0 1 0.9825 99.4 0.528 Contact Map
3bbo2 1 0.8246 98.6 0.646 Contact Map
3aieA 3 0.6491 12.7 0.909 Contact Map
1kb2A 2 0.2281 4.9 0.925 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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