GREMLIN Database
RL31B - 50S ribosomal protein L31 type B
UniProt: P0A7N1 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG14326
Length: 87 (80)
Sequences: 1005 (397)
Seq/√Len: 44.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
36_E41_T4.5491.00
13_V35_I4.1951.00
29_I45_V2.8841.00
33_R46_T2.7401.00
31_T45_V2.6711.00
10_R31_T2.4981.00
10_R30_K2.2391.00
37_L40_V2.0940.99
15_H22_Y2.0350.99
24_K37_L2.0160.99
13_V37_L1.9380.99
23_F51_S1.8410.99
11_T26_G1.8130.98
21_E52_K1.7910.98
19_V52_K1.7630.98
11_T40_V1.7050.98
22_Y37_L1.6390.97
34_E41_T1.6170.97
67_E71_A1.6070.97
17_T46_T1.5820.96
10_R29_I1.4940.95
22_Y35_I1.4530.94
15_H44_Y1.4320.94
15_H46_T1.2370.88
47_I50_S1.1980.86
62_R67_E1.1750.85
74_T79_R1.1450.83
57_Y62_R1.1220.82
60_K71_A1.0990.81
19_V46_T1.0900.80
19_V50_S1.0460.77
14_F51_S1.0190.75
21_E37_L1.0100.75
15_H19_V1.0090.74
13_V22_Y0.9870.73
15_H20_D0.9730.72
19_V53_S0.9570.70
18_S53_S0.9460.70
65_A74_T0.9410.69
48_D57_Y0.9400.69
75_Q78_G0.9340.69
49_V61_L0.9210.67
35_I44_Y0.9140.67
37_L42_Y0.9080.66
15_H35_I0.8820.64
65_A72_R0.8740.63
24_K42_Y0.8450.61
21_E25_I0.8390.60
31_T44_Y0.8050.57
18_S67_E0.7980.56
63_T66_S0.7850.55
20_D52_K0.7840.55
26_G67_E0.7790.55
8_E30_K0.7740.54
47_I74_T0.7490.52
20_D69_N0.7470.51
19_V22_Y0.7370.51
30_K45_V0.7340.50
61_L75_Q0.7330.50
66_S70_V0.7310.50
4_N30_K0.7300.50
32_D72_R0.7290.50
33_R44_Y0.7270.50
70_V74_T0.7240.49
20_D47_I0.7200.49
65_A77_F0.7180.49
17_T57_Y0.7160.48
49_V70_V0.7140.48
9_Y43_P0.7030.47
2_K72_R0.6870.46
18_S72_R0.6730.44
28_T45_V0.6720.44
2_K6_H0.6620.43
24_K35_I0.6550.43
33_R74_T0.6530.42
71_A75_Q0.6520.42
65_A70_V0.6480.42
4_N60_K0.6470.42
74_T78_G0.6440.42
77_F80_F0.6370.41
66_S69_N0.6360.41
69_N72_R0.6320.40
63_T75_Q0.6150.39
47_I77_F0.6140.39
3_P79_R0.6030.38
8_E34_E0.5990.37
1_M6_H0.5980.37
11_T24_K0.5960.37
17_T77_F0.5950.37
49_V76_R0.5940.37
66_S75_Q0.5890.37
4_N25_I0.5870.36
14_F53_S0.5830.36
46_T71_A0.5790.36
76_R79_R0.5790.36
11_T78_G0.5780.36
65_A69_N0.5760.35
3_P18_S0.5740.35
2_K60_K0.5730.35
65_A71_A0.5700.35
69_N76_R0.5680.35
68_G73_F0.5640.34
24_K69_N0.5580.34
55_P68_G0.5560.34
56_F70_V0.5530.33
63_T70_V0.5510.33
36_E47_I0.5480.33
33_R71_A0.5480.33
52_K63_T0.5360.32
63_T76_R0.5330.32
4_N8_E0.5290.31
49_V79_R0.5250.31
2_K5_I0.5240.31
42_Y55_P0.5170.30
10_R33_R0.5150.30
3_P78_G0.5110.30
66_S72_R0.5090.30
61_L64_V0.5090.30
3_P32_D0.5040.29
34_E74_T0.5000.29
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3f1f4 1 0.3448 100 0.354 Contact Map
4rb64 1 0.7931 100 0.357 Contact Map
1nkwY 1 0.8391 100 0.361 Contact Map
1vs6Z 1 0.8046 100 0.363 Contact Map
3bbo1 1 0.8161 100 0.378 Contact Map
1vw4V 1 0.5517 99.8 0.509 Contact Map
2k89A 1 0.7011 8.7 0.941 Contact Map
2ketA 1 0.2299 6.8 0.944 Contact Map
3tw8B 1 0.8851 6.3 0.944 Contact Map
4dapA 1 0.5172 6 0.945 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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