GREMLIN Database
RL20 - 50S ribosomal protein L20
UniProt: P0A7L3 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10881
Length: 118 (114)
Sequences: 2241 (937)
Seq/√Len: 87.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
21_A39_V3.8581.00
81_N85_K2.9081.00
69_A79_F2.8781.00
6_R10_A2.7091.00
66_N70_R2.7011.00
52_Q55_R2.6361.00
96_A100_V2.6281.00
28_R38_A2.5561.00
72_N107_T2.5201.00
102_D105_A2.2511.00
49_D52_Q2.1661.00
38_A42_A2.1451.00
27_A31_V2.1211.00
31_V34_V2.1141.00
53_R56_Q2.0361.00
97_D101_F2.0231.00
20_Q43_G1.8411.00
27_A30_R1.8211.00
108_A111_E1.8181.00
75_S78_K1.8021.00
34_V37_Q1.7561.00
48_R52_Q1.7331.00
83_L109_L1.7251.00
32_Y36_F1.6461.00
107_T111_E1.6421.00
36_F40_I1.6181.00
94_I97_D1.5501.00
111_E114_K1.5001.00
88_V112_K1.4350.99
108_A112_K1.3990.99
37_Q41_K1.3960.99
52_Q56_Q1.3670.99
9_I12_A1.3640.99
104_V107_T1.3310.99
8_V12_A1.3240.99
24_Y38_A1.2910.99
65_I96_A1.2890.99
41_K45_Y1.2800.99
90_I94_I1.2490.98
91_D94_I1.2310.98
18_L35_A1.1950.98
25_Y31_V1.1570.97
78_K81_N1.1320.97
98_I105_A1.0990.96
9_I13_R1.0870.96
69_A72_N1.0850.96
8_V14_H1.0830.96
27_A34_V1.0820.96
60_L64_R1.0790.96
71_Q103_K1.0790.96
103_K107_T1.0790.96
58_R80_I1.0660.95
86_A113_A1.0630.95
11_R14_H1.0620.95
69_A74_I1.0350.95
74_I114_K1.0250.94
6_R9_I1.0030.94
58_R62_I0.9960.93
98_I102_D0.9810.93
26_G29_S0.9810.93
82_G113_A0.9750.93
53_R57_F0.9510.92
40_I43_G0.9500.92
9_I14_H0.9320.91
98_I109_L0.9190.90
56_Q59_Q0.9190.90
58_R92_R0.9130.90
25_Y28_R0.8980.89
38_A41_K0.8930.89
14_H32_Y0.8870.89
4_V7_G0.8700.88
82_G86_A0.8670.87
59_Q63_A0.8470.86
28_R42_A0.8400.86
82_G85_K0.8320.85
17_I35_A0.8280.85
74_I78_K0.8220.85
20_Q39_V0.8160.84
17_I36_F0.8150.84
77_S81_N0.8140.84
31_V36_F0.8110.84
14_H18_L0.8050.83
104_V108_A0.7940.82
25_Y42_A0.7920.82
65_I80_I0.7900.82
48_R55_R0.7800.81
33_R37_Q0.7650.80
74_I82_G0.7650.80
85_K89_E0.7640.80
33_R40_I0.7570.79
32_Y35_A0.7550.79
71_Q107_T0.7460.78
72_N103_K0.7430.78
37_Q40_I0.7270.77
68_A72_N0.7210.76
45_Y110_V0.7150.75
10_A32_Y0.7000.74
105_A108_A0.7000.74
64_R100_V0.6950.73
22_K51_R0.6820.72
17_I40_I0.6740.71
90_I109_L0.6680.70
42_A45_Y0.6620.70
63_A91_D0.6620.70
18_L32_Y0.6610.69
79_F109_L0.6550.69
84_K89_E0.6470.68
110_V113_A0.6440.67
24_Y43_G0.6430.67
5_K9_I0.6400.67
2_A9_I0.6380.67
78_K82_G0.6300.66
45_Y48_R0.6270.65
91_D112_K0.6200.65
10_A14_H0.6190.64
47_Y51_R0.6180.64
107_T110_V0.6160.64
62_I76_Y0.6100.63
24_Y39_V0.6010.62
83_L88_V0.5960.62
6_R14_H0.5950.61
36_F109_L0.5900.61
87_S101_F0.5860.60
72_N110_V0.5850.60
74_I110_V0.5830.60
68_A110_V0.5790.59
17_I20_Q0.5730.59
43_G51_R0.5690.58
97_D100_V0.5680.58
80_I84_K0.5660.58
54_K93_K0.5640.57
7_G10_A0.5620.57
30_R36_F0.5610.57
79_F110_V0.5600.57
84_K90_I0.5600.57
4_V9_I0.5590.57
12_A59_Q0.5560.56
83_L114_K0.5560.56
16_K20_Q0.5530.56
107_T114_K0.5530.56
38_A45_Y0.5510.56
4_V12_A0.5510.56
68_A106_F0.5510.56
17_I39_V0.5510.56
27_A38_A0.5460.55
40_I44_Q0.5420.54
6_R11_R0.5410.54
23_G47_Y0.5400.54
12_A27_A0.5390.54
47_Y108_A0.5390.54
69_A110_V0.5380.54
21_A24_Y0.5320.53
70_R73_G0.5310.53
21_A99_A0.5290.53
70_R75_S0.5280.53
68_A99_A0.5220.52
19_K25_Y0.5210.52
90_I98_I0.5210.52
69_A75_S0.5190.51
25_Y29_S0.5190.51
45_Y94_I0.5150.51
13_R101_F0.5130.50
109_L112_K0.5120.50
53_R100_V0.5070.50
72_N111_E0.5040.49
2_A24_Y0.5040.49
74_I79_F0.5030.49
9_I16_K0.5030.49
41_K44_Q0.5010.49
52_Q59_Q0.5000.49
4_V37_Q0.5000.49
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4rb6U 1 0.9831 100 0.001 Contact Map
2zjrN 1 0.9915 100 0.002 Contact Map
3j3wQ 1 0.9915 100 0.008 Contact Map
4tp9Q 1 0.9915 100 0.025 Contact Map
2ghjA 4 0.839 100 0.04 Contact Map
3bboS 1 0.9915 100 0.048 Contact Map
3j7yR 1 0.9831 100 0.065 Contact Map
1vx7J 1 0.9153 49.3 0.921 Contact Map
4w20G 1 0.9915 33.7 0.928 Contact Map
4a17F 1 0.9915 29.8 0.93 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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