GREMLIN Database
RL11 - 50S ribosomal protein L11
UniProt: P0A7J7 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10872
Length: 142 (139)
Sequences: 2139 (857)
Seq/√Len: 72.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
37_E41_A3.6621.00
80_L138_L3.5291.00
80_L101_I3.0701.00
100_K139_V2.9041.00
107_Q111_Q2.8521.00
44_A47_D2.7431.00
17_M51_K2.7131.00
7_A31_Q2.5971.00
92_K96_D2.5761.00
103_R130_E2.4121.00
26_P30_Q2.3711.00
76_A129_I2.3371.00
4_K63_A2.3221.00
107_Q126_T2.2851.00
92_K95_K2.2571.00
100_K141_E2.2421.00
102_S105_Q2.2081.00
55_I71_T2.1821.00
33_V61_V2.0941.00
9_V61_V2.0831.00
83_A108_E1.8041.00
94_N97_K1.6961.00
13_V24_V1.6711.00
41_A45_K1.6651.00
104_A107_Q1.6411.00
53_L78_V1.6361.00
84_A101_I1.6330.99
106_L126_T1.5750.99
97_K139_V1.5110.99
106_L130_E1.5000.99
5_V60_T1.4360.99
19_N39_C1.4080.98
36_M40_K1.3570.98
103_R126_T1.3250.98
108_E111_Q1.3160.98
8_Y58_V1.2910.97
90_S94_N1.2880.97
104_A108_E1.2860.97
105_Q108_E1.2780.97
14_A17_M1.2660.97
88_S91_G1.2380.97
122_I126_T1.2180.96
23_P26_P1.2060.96
47_D51_K1.1990.96
73_T115_A1.1990.96
114_A119_G1.1990.96
120_A124_A1.1850.96
121_D124_A1.1650.95
106_L129_I1.1580.95
127_R130_E1.1490.95
119_G125_M1.1450.95
9_V31_Q1.1390.95
58_V72_K1.1300.94
80_L84_A1.1120.94
78_V81_K1.1080.94
119_G124_A1.1020.93
91_G96_D1.0970.93
117_M125_M1.0910.93
81_K86_I1.0770.93
103_R106_L1.0680.92
14_A54_P1.0520.92
53_L82_K1.0520.92
114_A125_M1.0460.92
42_F58_V1.0380.91
90_S96_D1.0360.91
84_A138_L1.0250.91
126_T130_E1.0220.91
34_N37_E1.0100.90
79_L112_T1.0090.90
13_V54_P0.9880.89
50_E54_P0.9830.89
30_Q35_I0.9790.89
73_T76_A0.9560.87
86_I138_L0.9550.87
81_K88_S0.9380.86
77_A132_T0.9340.86
33_V66_S0.9300.86
54_P78_V0.9170.85
101_I138_L0.9150.85
118_T128_S0.9150.85
110_A122_I0.9080.85
62_Y68_T0.9010.84
80_L133_A0.8960.84
108_E112_T0.8710.82
107_Q122_I0.8650.82
5_V8_Y0.8600.81
111_Q122_I0.8590.81
45_K69_F0.8480.80
82_K85_G0.8460.80
11_L24_V0.8430.80
37_E40_K0.8350.79
76_A101_I0.8290.79
83_A112_T0.8290.79
84_A99_G0.8240.78
124_A127_R0.8240.78
6_Q63_A0.8180.78
30_Q33_V0.8170.78
55_I74_P0.8150.78
99_G138_L0.8090.77
29_G135_S0.8080.77
57_V71_T0.8010.76
73_T114_A0.7940.76
91_G94_N0.7920.76
88_S96_D0.7780.74
31_Q65_R0.7720.74
36_M44_A0.7530.72
36_M67_F0.7410.71
77_A94_N0.7390.70
103_R107_Q0.7300.70
84_A98_V0.7280.69
6_Q60_T0.7260.69
36_M39_C0.7260.69
86_I98_V0.7190.68
37_E65_R0.7190.68
13_V42_F0.7150.68
50_E53_L0.7120.68
58_V70_V0.7110.68
41_A69_F0.7040.67
74_P79_L0.7010.66
77_A91_G0.7010.66
114_A118_T0.7000.66
94_N98_V0.6920.65
38_F42_F0.6920.65
90_S97_K0.6910.65
22_P26_P0.6890.65
83_A109_I0.6850.65
99_G139_V0.6840.65
101_I106_L0.6800.64
2_A30_Q0.6790.64
42_F54_P0.6780.64
19_N35_I0.6780.64
131_G135_S0.6770.64
17_M52_G0.6730.63
42_F63_A0.6730.63
9_V33_V0.6720.63
20_P59_I0.6680.63
24_V69_F0.6680.63
117_M128_S0.6670.63
11_L57_V0.6660.62
130_E134_R0.6630.62
56_P73_T0.6620.62
75_P136_M0.6620.62
17_M87_K0.6590.62
106_L120_A0.6520.61
83_A105_Q0.6510.61
9_V59_I0.6490.60
13_V71_T0.6460.60
111_Q126_T0.6410.60
123_E126_T0.6400.59
90_S93_P0.6360.59
107_Q110_A0.6330.59
2_A8_Y0.6320.58
101_I140_V0.6210.57
26_P61_V0.6200.57
13_V35_I0.6160.56
118_T125_M0.6140.56
124_A128_S0.6140.56
50_E82_K0.6100.56
31_Q61_V0.6100.56
40_K44_A0.6080.56
81_K89_G0.6080.56
32_G65_R0.6060.55
21_S27_A0.6040.55
41_A67_F0.6020.55
114_A117_M0.5960.54
102_S141_E0.5900.53
74_P112_T0.5870.53
36_M47_D0.5850.53
46_T55_I0.5830.52
48_S51_K0.5810.52
50_E112_T0.5790.52
21_S26_P0.5770.52
46_T62_Y0.5740.51
84_A106_L0.5720.51
84_A140_V0.5700.51
46_T71_T0.5670.50
13_V31_Q0.5650.50
18_A25_G0.5640.50
111_Q114_A0.5620.50
123_E127_R0.5590.49
56_P59_I0.5510.49
101_I109_I0.5480.48
26_P35_I0.5480.48
27_A61_V0.5460.48
15_A71_T0.5460.48
68_T71_T0.5450.48
17_M47_D0.5450.48
132_T136_M0.5400.47
45_K71_T0.5370.47
31_Q132_T0.5350.47
106_L140_V0.5340.46
36_M41_A0.5330.46
62_Y66_S0.5330.46
4_K68_T0.5270.46
103_R123_E0.5270.46
11_L26_P0.5190.45
38_F43_N0.5190.45
24_V27_A0.5170.44
6_Q31_Q0.5160.44
121_D126_T0.5160.44
30_Q81_K0.5160.44
21_S41_A0.5130.44
104_A112_T0.5130.44
65_R71_T0.5110.44
12_Q42_F0.5060.43
27_A69_F0.5020.42
20_P39_C0.5000.42
70_V115_A0.5000.42
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4tp9I 1 0.0141 100 0.112 Contact Map
3bboK 1 0.9859 100 0.118 Contact Map
3j7yJ 1 0.9577 100 0.118 Contact Map
1mmsA 1 0.9366 100 0.128 Contact Map
3j21H 1 0.9366 100 0.135 Contact Map
3egvB 1 0.5423 100 0.136 Contact Map
1vq8I 1 0.493 100 0.147 Contact Map
3j61K 1 0.8803 100 0.181 Contact Map
4w22K 1 0.9225 100 0.194 Contact Map
3zf7M 1 0.9437 100 0.2 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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