RF3 - ECOLI - GREMLIN Contacts

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RF3 - Peptide chain release factor 3

UniProt:	P0A7I4	Sequences: MTLSPYLQEVAKRRTFAIISHPDAGKTTITEKVLLFGQAIQTAGTVKGRGSNQHAKSDWMEMEKQRGISITTSVMQFPYHDCLVNLLDTPGHEDFSEDTYRTLTAVDCCLMVIDAAKGVEDRTRKLMEVTRLRDTPILTFMNKLDRDIRDPMELLDEVENELKIGCAPITWPIGCGKLFKGVYHLYKDETYLYQSGKGHTIQEVRIVKGLNNPDLDAAVGEDLAQQLRDELELVKGASNEFDKELFLAGEITPVFFGTALGNFGVDHMLDGLVEWAPAPMPRQTDTRTVEASEDKFTGFVFKIQANMDPKHRDRVAFMRVVSGKYEKGMKLRQVRTAKDVVISDALTFMAGDRSHVEEAYPGDILGLHNHGTIQIGDTFTQGEMMKFTGIPNFAPELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPISNNDLIVGAVGVLQFDVVVARLKSEYNVEAVYESVNVATARWVECADAKKFEEFKRKNESQLALDGGDNLAYIATSMVNLRLAQERYPDVQFHQTREH	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12114
Length:	529 (479)
Sequences:	6963 (3284)
Seq/√Len:	150.0

ECOLI - RF3 EFG LEPA TYPA
BACSU - EFG TYPA LEPA
HALSA - EF2
SULSO - EF2 IF2P

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
359_A	365_L	6.273	1.00
481_K	496_D	4.161	1.00
140_F	257_G	3.877	1.00
255_F	271_G	3.580	1.00
226_Q	237_A	3.444	1.00
140_F	259_A	3.431	1.00
116_A	146_R	3.390	1.00
479_A	500_N	3.344	1.00
454_K	460_E	3.325	1.00
326_E	358_E	3.105	1.00
324_K	358_E	2.955	1.00
404_K	462_V	2.946	1.00
300_V	316_A	2.937	1.00
114_D	117_K	2.915	1.00
318_M	367_L	2.881	1.00
285_D	290_E	2.871	1.00
225_Q	229_D	2.840	1.00
239_N	274_E	2.833	1.00
314_R	421_E	2.756	1.00
57_S	75_M	2.750	1.00
113_I	123_T	2.688	1.00
156_D	160_N	2.674	1.00
30_T	86_L	2.662	1.00
169_I	255_F	2.657	1.00
234_V	237_A	2.601	1.00
415_G	453_L	2.568	1.00
404_K	460_E	2.557	1.00
398_F	439_G	2.469	1.00
296_F	331_L	2.457	1.00
402_R	462_V	2.390	1.00
425_V	438_V	2.283	1.00
483_E	494_A	2.243	1.00
320_V	359_A	2.227	1.00
208_K	211_N	2.221	1.00
189_E	203_E	2.206	1.00
153_E	157_E	2.072	1.00
139_T	158_V	2.045	1.00
173_I	190_T	2.033	1.00
46_V	55_A	2.027	1.00
438_V	449_V	1.998	1.00
124_R	161_E	1.974	1.00
334_V	380_T	1.961	1.00
59_W	71_T	1.955	1.00
19_I	111_M	1.953	1.00
154_L	157_E	1.949	1.00
451_A	455_S	1.942	1.00
167_A	251_I	1.910	1.00
318_M	365_L	1.910	1.00
191_Y	267_H	1.903	1.00
194_Q	202_Q	1.893	1.00
16_F	84_V	1.889	1.00
187_K	235_K	1.872	1.00
61_E	65_Q	1.871	1.00
320_V	365_L	1.850	1.00
222_D	225_Q	1.812	1.00
481_K	498_G	1.797	1.00
345_A	367_L	1.795	1.00
483_E	496_D	1.765	1.00
298_G	318_M	1.765	1.00
370_H	373_I	1.756	1.00
152_M	213_P	1.753	1.00
394_A	426_Q	1.753	1.00
61_E	64_K	1.738	1.00
335_R	377_D	1.720	1.00
220_G	244_E	1.715	1.00
80_H	274_E	1.699	1.00
330_K	339_D	1.695	1.00
291_A	294_D	1.694	1.00
17_A	106_V	1.693	1.00
40_I	56_K	1.690	1.00
336_T	374_Q	1.686	1.00
19_I	109_C	1.678	1.00
113_I	158_V	1.666	1.00
402_R	464_E	1.661	1.00
183_Y	210_L	1.660	1.00
244_E	248_A	1.659	1.00
405_D	408_K	1.644	1.00
327_K	357_E	1.638	1.00
399_R	463_Y	1.616	1.00
80_H	270_D	1.606	1.00
243_K	247_L	1.598	1.00
115_A	141_M	1.598	1.00
297_T	387_F	1.591	1.00
477_A	500_N	1.591	1.00
332_R	337_A	1.589	1.00
233_L	241_F	1.588	1.00
296_F	320_V	1.584	1.00
347_T	356_V	1.583	1.00
482_F	495_L	1.580	1.00
30_T	57_S	1.577	1.00
82_C	273_V	1.564	1.00
331_L	342_I	1.558	1.00
37_G	77_F	1.546	1.00
398_F	437_I	1.542	1.00
72_T	87_L	1.539	1.00
15_T	85_N	1.533	1.00
326_E	329_M	1.517	1.00
29_I	259_A	1.517	1.00
131_R	137_I	1.516	1.00
450_V	454_K	1.514	1.00
425_V	449_V	1.511	1.00
78_P	83_L	1.508	1.00
185_L	188_D	1.505	1.00
29_I	112_V	1.489	1.00
155_L	168_P	1.488	1.00
77_F	86_L	1.487	1.00
115_A	144_L	1.485	1.00
78_P	81_D	1.481	1.00
79_Y	270_D	1.480	1.00
57_S	73_S	1.479	1.00
18_I	30_T	1.478	1.00
487_R	492_Q	1.475	1.00
324_K	360_Y	1.460	1.00
12_K	82_C	1.456	1.00
420_S	425_V	1.454	1.00
479_A	498_G	1.453	1.00
233_L	237_A	1.450	1.00
344_D	355_H	1.438	1.00
138_L	276_A	1.436	1.00
192_L	204_V	1.436	1.00
189_E	205_R	1.433	1.00
214_D	217_A	1.432	1.00
482_F	485_F	1.422	1.00
171_W	210_L	1.421	1.00
126_L	129_V	1.415	1.00
295_K	381_Q	1.414	1.00
155_L	254_V	1.413	1.00
12_K	81_D	1.403	1.00
412_L	453_L	1.395	1.00
75_M	349_M	1.373	1.00
45_T	48_G	1.360	1.00
428_F	439_G	1.359	1.00
40_I	43_A	1.354	1.00
114_D	154_L	1.353	1.00
144_L	175_C	1.349	1.00
108_C	276_A	1.348	1.00
300_V	373_I	1.347	1.00
224_A	228_R	1.344	1.00
450_V	463_Y	1.342	1.00
210_L	213_P	1.335	1.00
356_V	359_A	1.331	1.00
485_F	492_Q	1.330	1.00
420_S	438_V	1.321	1.00
226_Q	231_L	1.311	1.00
338_K	372_T	1.306	1.00
240_E	244_E	1.304	1.00
57_S	69_S	1.295	1.00
332_R	339_D	1.292	1.00
111_M	139_T	1.292	1.00
152_M	156_D	1.290	1.00
65_Q	455_S	1.283	1.00
59_W	304_Q	1.278	1.00
173_I	183_Y	1.261	1.00
188_D	206_I	1.258	1.00
484_E	491_S	1.248	1.00
214_D	218_A	1.246	1.00
14_R	279_P	1.246	1.00
62_M	70_I	1.245	1.00
36_F	266_D	1.237	1.00
97_E	424_A	1.233	1.00
325_Y	331_L	1.225	1.00
452_R	456_E	1.217	1.00
314_R	424_A	1.215	1.00
19_I	103_L	1.212	1.00
270_D	273_V	1.211	1.00
424_A	427_V	1.204	1.00
221_E	225_Q	1.200	1.00
216_D	245_L	1.190	1.00
184_H	187_K	1.189	1.00
482_F	498_G	1.188	1.00
62_M	451_A	1.187	1.00
180_K	192_L	1.187	1.00
114_D	146_R	1.182	1.00
80_H	273_V	1.181	1.00
29_I	268_M	1.175	1.00
226_Q	234_V	1.174	1.00
130_T	137_I	1.169	1.00
297_T	322_S	1.168	1.00
216_D	219_V	1.165	1.00
359_A	363_D	1.164	1.00
487_R	490_E	1.161	1.00
187_K	203_E	1.160	1.00
325_Y	342_I	1.149	1.00
157_E	161_E	1.146	1.00
195_S	199_H	1.146	1.00
114_D	157_E	1.142	1.00
139_T	252_T	1.132	1.00
77_F	84_V	1.131	1.00
482_F	496_D	1.129	1.00
20_S	24_A	1.122	0.99
489_N	492_Q	1.120	0.99
205_R	208_K	1.118	0.99
239_N	275_W	1.118	0.99
113_I	139_T	1.116	0.99
303_I	375_I	1.110	0.99
278_A	281_P	1.110	0.99
111_M	126_L	1.110	0.99
191_Y	203_E	1.110	0.99
152_M	171_W	1.109	0.99
430_P	433_N	1.108	0.99
272_L	276_A	1.108	0.99
87_L	106_V	1.106	0.99
415_G	419_L	1.105	0.99
243_K	281_P	1.105	0.99
169_I	271_G	1.103	0.99
340_V	373_I	1.092	0.99
294_D	322_S	1.089	0.99
142_N	259_A	1.089	0.99
60_M	71_T	1.087	0.99
100_Y	132_L	1.082	0.99
315_V	366_G	1.081	0.99
432_S	471_A	1.080	0.99
488_K	492_Q	1.077	0.99
123_T	139_T	1.075	0.99
207_V	211_N	1.066	0.99
119_V	123_T	1.066	0.99
330_K	341_V	1.064	0.99
144_L	179_F	1.064	0.99
359_A	367_L	1.064	0.99
486_K	490_E	1.057	0.99
83_L	363_D	1.055	0.99
488_K	491_S	1.050	0.99
151_P	168_P	1.050	0.99
300_V	318_M	1.047	0.99
150_D	153_E	1.044	0.99
402_R	435_D	1.042	0.99
482_F	486_K	1.040	0.99
141_M	154_L	1.040	0.99
427_V	436_L	1.039	0.99
490_E	493_L	1.039	0.99
304_Q	317_F	1.038	0.99
221_E	250_E	1.037	0.99
66_R	451_A	1.034	0.99
156_D	159_E	1.027	0.99
318_M	325_Y	1.026	0.99
220_G	224_A	1.025	0.99
29_I	265_V	1.023	0.99
408_K	411_Q	1.022	0.99
111_M	123_T	1.022	0.99
107_D	319_R	1.022	0.99
485_F	496_D	1.021	0.99
209_G	212_N	1.012	0.99
173_I	210_L	1.011	0.99
258_T	261_G	1.010	0.99
187_K	239_N	1.010	0.99
296_F	325_Y	1.010	0.99
36_F	262_N	1.009	0.99
346_L	355_H	1.009	0.99
249_G	252_T	1.009	0.99
420_S	427_V	1.004	0.99
110_L	268_M	1.004	0.99
424_A	428_F	1.002	0.99
83_L	347_T	1.002	0.99
61_E	455_S	0.987	0.99
360_Y	363_D	0.986	0.99
47_K	55_A	0.984	0.99
333_Q	336_T	0.982	0.99
117_K	157_E	0.981	0.99
141_M	254_V	0.977	0.99
301_F	364_I	0.973	0.99
415_G	459_V	0.969	0.98
109_C	135_T	0.965	0.98
65_Q	451_A	0.965	0.98
217_A	241_F	0.964	0.98
190_T	207_V	0.963	0.98
245_L	251_I	0.958	0.98
308_D	311_H	0.949	0.98
33_V	77_F	0.938	0.98
215_L	218_A	0.938	0.98
245_L	250_E	0.938	0.98
333_Q	373_I	0.936	0.98
119_V	162_L	0.933	0.98
317_F	348_F	0.928	0.98
59_W	351_G	0.927	0.98
440_A	446_F	0.920	0.98
435_D	464_E	0.919	0.98
381_Q	384_M	0.919	0.98
100_Y	129_V	0.917	0.98
105_A	301_F	0.916	0.98
28_T	43_A	0.913	0.98
158_V	254_V	0.907	0.98
216_D	223_L	0.906	0.98
290_E	294_D	0.906	0.98
292_S	324_K	0.903	0.98
485_F	488_K	0.902	0.98
198_G	201_I	0.902	0.98
347_T	354_S	0.902	0.98
132_L	391_P	0.900	0.98
108_C	277_P	0.893	0.97
97_E	392_N	0.891	0.97
413_L	436_L	0.889	0.97
76_Q	83_L	0.885	0.97
320_V	360_Y	0.885	0.97
348_F	366_G	0.884	0.97
138_L	271_G	0.880	0.97
222_D	226_Q	0.880	0.97
110_L	272_L	0.879	0.97
221_E	224_A	0.879	0.97
495_L	499_D	0.879	0.97
214_D	221_E	0.877	0.97
20_S	23_D	0.876	0.97
204_V	208_K	0.874	0.97
55_A	64_K	0.873	0.97
209_G	213_P	0.871	0.97
285_D	294_D	0.867	0.97
127_M	137_I	0.863	0.97
70_I	448_V	0.862	0.97
347_T	359_A	0.861	0.97
206_I	211_N	0.859	0.97
222_D	237_A	0.855	0.97
235_K	239_N	0.854	0.97
187_K	191_Y	0.853	0.97
35_L	43_A	0.851	0.97
114_D	120_E	0.850	0.96
226_Q	233_L	0.849	0.96
318_M	359_A	0.849	0.96
31_E	55_A	0.848	0.96
219_V	241_F	0.844	0.96
205_R	209_G	0.844	0.96
331_L	379_F	0.843	0.96
28_T	46_V	0.842	0.96
16_F	272_L	0.841	0.96
242_D	251_I	0.839	0.96
327_K	355_H	0.838	0.96
292_S	360_Y	0.836	0.96
487_R	493_L	0.836	0.96
266_D	270_D	0.833	0.96
483_E	487_R	0.832	0.96
484_E	487_R	0.832	0.96
158_V	166_C	0.830	0.96
196_G	199_H	0.830	0.96
45_T	55_A	0.830	0.96
487_R	491_S	0.829	0.96
40_I	46_V	0.827	0.96
215_L	220_G	0.827	0.96
485_F	491_S	0.826	0.96
400_R	435_D	0.826	0.96
13_R	83_L	0.824	0.96
482_F	491_S	0.822	0.96
271_G	275_W	0.821	0.96
45_T	54_H	0.818	0.96
217_A	220_G	0.817	0.96
170_T	256_F	0.817	0.96
483_E	488_K	0.814	0.96
484_E	495_L	0.813	0.95
485_F	494_A	0.813	0.95
39_A	349_M	0.811	0.95
218_A	224_A	0.810	0.95
234_V	238_S	0.809	0.95
356_V	365_L	0.808	0.95
47_K	260_L	0.806	0.95
346_L	368_H	0.804	0.95
303_I	316_A	0.804	0.95
85_N	363_D	0.803	0.95
484_E	493_L	0.802	0.95
340_V	371_G	0.799	0.95
170_T	182_V	0.799	0.95
236_G	240_E	0.798	0.95
483_E	495_L	0.798	0.95
203_E	206_I	0.797	0.95
114_D	143_K	0.796	0.95
486_K	489_N	0.793	0.95
214_D	220_G	0.790	0.95
380_T	385_M	0.789	0.95
326_E	357_E	0.785	0.95
159_E	165_G	0.784	0.95
112_V	142_N	0.783	0.94
216_D	224_A	0.782	0.94
220_G	223_L	0.782	0.94
488_K	493_L	0.782	0.94
174_G	179_F	0.781	0.94
339_D	382_G	0.780	0.94
170_T	184_H	0.776	0.94
138_L	246_F	0.775	0.94
316_A	373_I	0.774	0.94
441_V	445_Q	0.769	0.94
217_A	227_L	0.769	0.94
291_A	295_K	0.768	0.94
107_D	136_P	0.767	0.94
104_T	390_I	0.765	0.94
84_V	273_V	0.762	0.94
414_K	418_Q	0.760	0.94
165_G	215_L	0.758	0.93
169_I	242_D	0.758	0.93
100_Y	126_L	0.754	0.93
151_P	256_F	0.754	0.93
218_A	221_E	0.753	0.93
218_A	223_L	0.752	0.93
208_K	212_N	0.751	0.93
491_S	494_A	0.751	0.93
443_V	447_D	0.750	0.93
30_T	75_M	0.749	0.93
153_E	156_D	0.748	0.93
64_K	351_G	0.747	0.93
309_P	312_R	0.747	0.93
89_T	99_T	0.745	0.93
141_M	155_L	0.744	0.93
174_G	180_K	0.742	0.93
226_Q	230_E	0.741	0.93
486_K	495_L	0.740	0.93
486_K	492_Q	0.740	0.93
217_A	221_E	0.738	0.93
188_D	235_K	0.737	0.92
31_E	44_G	0.737	0.92
207_V	210_L	0.736	0.92
481_K	484_E	0.736	0.92
192_L	202_Q	0.735	0.92
217_A	233_L	0.732	0.92
139_T	254_V	0.728	0.92
217_A	223_L	0.727	0.92
419_L	453_L	0.727	0.92
115_A	148_I	0.726	0.92
117_K	120_E	0.725	0.92
170_T	255_F	0.725	0.92
205_R	211_N	0.725	0.92
480_K	495_L	0.724	0.92
483_E	491_S	0.723	0.92
217_A	228_R	0.721	0.92
186_Y	235_K	0.721	0.92
44_G	54_H	0.720	0.92
435_D	466_V	0.719	0.92
270_D	274_E	0.719	0.92
42_T	53_Q	0.717	0.91
486_K	493_L	0.714	0.91
298_G	325_Y	0.714	0.91
397_L	443_V	0.713	0.91
423_G	445_Q	0.709	0.91
218_A	227_L	0.709	0.91
180_K	209_G	0.707	0.91
487_R	495_L	0.705	0.91
34_L	56_K	0.702	0.91
297_T	385_M	0.701	0.91
29_I	33_V	0.699	0.90
68_I	92_H	0.699	0.90
298_G	367_L	0.699	0.90
17_A	103_L	0.697	0.90
194_Q	204_V	0.696	0.90
312_R	346_L	0.695	0.90
412_L	459_V	0.694	0.90
342_I	367_L	0.693	0.90
19_I	390_I	0.691	0.90
219_V	245_L	0.691	0.90
104_T	299_F	0.690	0.90
206_I	210_L	0.689	0.90
193_Y	201_I	0.689	0.90
257_G	268_M	0.688	0.90
207_V	212_N	0.687	0.90
13_R	363_D	0.687	0.90
411_Q	414_K	0.686	0.90
488_K	495_L	0.685	0.89
399_R	450_V	0.684	0.89
490_E	494_A	0.683	0.89
242_D	275_W	0.683	0.89
495_L	498_G	0.682	0.89
33_V	265_V	0.682	0.89
329_M	381_Q	0.682	0.89
492_Q	495_L	0.681	0.89
484_E	489_N	0.681	0.89
117_K	154_L	0.680	0.89
429_R	434_N	0.679	0.89
299_F	390_I	0.677	0.89
223_L	241_F	0.676	0.89
74_V	364_I	0.676	0.89
234_V	240_E	0.676	0.89
489_N	495_L	0.672	0.89
44_G	53_Q	0.672	0.89
137_I	249_G	0.671	0.89
223_L	237_A	0.671	0.89
19_I	126_L	0.671	0.89
72_T	102_T	0.670	0.88
489_N	493_L	0.670	0.88
220_G	238_S	0.670	0.88
305_A	314_R	0.670	0.88
99_T	126_L	0.670	0.88
139_T	154_L	0.670	0.88
43_A	262_N	0.668	0.88
182_V	267_H	0.667	0.88
482_F	497_G	0.666	0.88
179_F	182_V	0.662	0.88
141_M	158_V	0.661	0.88
60_M	452_R	0.659	0.88
174_G	178_L	0.659	0.88
425_V	428_F	0.659	0.88
167_A	242_D	0.658	0.88
491_S	496_D	0.656	0.87
37_G	269_L	0.655	0.87
194_Q	197_K	0.655	0.87
484_E	496_D	0.655	0.87
225_Q	228_R	0.654	0.87
144_L	149_R	0.652	0.87
346_L	353_R	0.652	0.87
202_Q	206_I	0.651	0.87
58_D	63_E	0.650	0.87
62_M	65_Q	0.649	0.87
308_D	312_R	0.648	0.87
481_K	485_F	0.648	0.87
491_S	495_L	0.647	0.87
321_V	387_F	0.647	0.87
347_T	363_D	0.646	0.87
93_E	125_K	0.645	0.87
109_C	130_T	0.645	0.87
223_L	238_S	0.644	0.86
490_E	495_L	0.643	0.86
440_A	449_V	0.643	0.86
334_V	386_K	0.642	0.86
92_H	101_R	0.641	0.86
224_A	227_L	0.640	0.86
223_L	226_Q	0.640	0.86
145_D	258_T	0.640	0.86
482_F	493_L	0.640	0.86
345_A	356_V	0.640	0.86
234_V	241_F	0.637	0.86
141_M	146_R	0.636	0.86
23_D	68_I	0.636	0.86
173_I	181_G	0.632	0.85
159_E	166_C	0.631	0.85
330_K	382_G	0.631	0.85
400_R	464_E	0.631	0.85
294_D	324_K	0.631	0.85
164_I	252_T	0.630	0.85
20_S	69_S	0.629	0.85
480_K	496_D	0.629	0.85
332_R	384_M	0.629	0.85
217_A	230_E	0.629	0.85
317_F	366_G	0.628	0.85
221_E	228_R	0.627	0.85
481_K	495_L	0.626	0.85
59_W	350_A	0.625	0.85
19_I	130_T	0.623	0.85
186_Y	275_W	0.622	0.84
27_T	34_L	0.622	0.84
298_G	320_V	0.621	0.84
54_H	64_K	0.621	0.84
408_K	412_L	0.620	0.84
97_E	389_G	0.618	0.84
33_V	37_G	0.617	0.84
340_V	370_H	0.616	0.84
214_D	223_L	0.615	0.84
416_L	420_S	0.615	0.84
47_K	67_G	0.615	0.84
480_K	497_G	0.614	0.84
126_L	130_T	0.614	0.84
167_A	170_T	0.614	0.84
103_L	109_C	0.614	0.84
193_Y	266_D	0.613	0.84
141_M	168_P	0.613	0.84
483_E	486_K	0.613	0.84
36_F	198_G	0.613	0.84
104_T	129_V	0.612	0.84
214_D	224_A	0.612	0.84
238_S	242_D	0.611	0.83
95_F	448_V	0.611	0.83
71_T	452_R	0.611	0.83
117_K	146_R	0.610	0.83
215_L	219_V	0.610	0.83
23_D	143_K	0.610	0.83
399_R	438_V	0.610	0.83
333_Q	340_V	0.608	0.83
39_A	75_M	0.608	0.83
305_A	418_Q	0.607	0.83
55_A	75_M	0.606	0.83
292_S	361_P	0.606	0.83
220_G	227_L	0.605	0.83
149_R	157_E	0.604	0.83
332_R	380_T	0.604	0.83
335_R	386_K	0.603	0.83
344_D	368_H	0.602	0.83
157_E	160_N	0.601	0.82
482_F	488_K	0.601	0.82
216_D	238_S	0.600	0.82
174_G	181_G	0.598	0.82
493_L	497_G	0.598	0.82
202_Q	212_N	0.598	0.82
414_K	417_V	0.598	0.82
485_F	489_N	0.597	0.82
171_W	213_P	0.597	0.82
165_G	250_E	0.597	0.82
65_Q	456_E	0.596	0.82
483_E	493_L	0.596	0.82
34_L	75_M	0.596	0.82
296_F	365_L	0.596	0.82
256_F	445_Q	0.593	0.82
401_I	463_Y	0.593	0.82
332_R	382_G	0.591	0.81
428_F	437_I	0.591	0.81
13_R	85_N	0.591	0.81
214_D	227_L	0.590	0.81
449_V	453_L	0.589	0.81
484_E	488_K	0.589	0.81
47_K	57_S	0.587	0.81
346_L	356_V	0.587	0.81
134_D	249_G	0.586	0.81
476_C	480_K	0.584	0.81
222_D	229_D	0.583	0.80
108_C	272_L	0.581	0.80
33_V	269_L	0.581	0.80
293_E	324_K	0.579	0.80
219_V	250_E	0.578	0.80
35_L	40_I	0.578	0.80
237_A	240_E	0.578	0.80
374_Q	421_E	0.577	0.80
333_Q	377_D	0.577	0.80
487_R	494_A	0.575	0.80
493_L	499_D	0.574	0.79
105_A	135_T	0.574	0.79
405_D	460_E	0.574	0.79
151_P	154_L	0.574	0.79
184_H	189_E	0.573	0.79
410_K	414_K	0.572	0.79
111_M	137_I	0.572	0.79
437_I	466_V	0.571	0.79
305_A	421_E	0.571	0.79
483_E	492_Q	0.571	0.79
111_M	130_T	0.570	0.79
412_L	416_L	0.569	0.79
217_A	238_S	0.568	0.79
186_Y	238_S	0.568	0.79
62_M	66_R	0.567	0.79
332_R	336_T	0.567	0.79
484_E	492_Q	0.567	0.79
108_C	246_F	0.566	0.79
231_L	235_K	0.566	0.79
216_D	228_R	0.566	0.79
216_D	220_G	0.563	0.78
296_F	324_K	0.561	0.78
29_I	258_T	0.560	0.78
419_L	457_Y	0.560	0.78
59_W	73_S	0.559	0.78
37_G	79_Y	0.558	0.78
73_S	87_L	0.558	0.78
13_R	314_R	0.558	0.78
112_V	140_F	0.558	0.78
259_A	265_V	0.557	0.77
236_G	239_N	0.557	0.77
22_P	69_S	0.556	0.77
170_T	267_H	0.556	0.77
227_L	230_E	0.556	0.77
48_G	54_H	0.555	0.77
96_S	441_V	0.554	0.77
177_K	180_K	0.554	0.77
32_K	36_F	0.553	0.77
188_D	211_N	0.550	0.77
37_G	86_L	0.550	0.77
191_Y	201_I	0.549	0.76
482_F	487_R	0.548	0.76
335_R	373_I	0.546	0.76
419_L	449_V	0.546	0.76
98_D	302_K	0.545	0.76
284_T	290_E	0.545	0.76
116_A	260_L	0.544	0.76
140_F	255_F	0.543	0.76
485_F	493_L	0.542	0.76
114_D	153_E	0.540	0.75
155_L	166_C	0.538	0.75
303_I	421_E	0.537	0.75
223_L	233_L	0.536	0.75
285_D	385_M	0.536	0.75
198_G	266_D	0.535	0.75
149_R	154_L	0.534	0.74
220_G	228_R	0.534	0.74
29_I	260_L	0.534	0.74
66_R	448_V	0.533	0.74
23_D	122_R	0.531	0.74
327_K	344_D	0.530	0.74
170_T	186_Y	0.530	0.74
181_G	190_T	0.530	0.74
147_D	177_K	0.529	0.74
96_S	129_V	0.529	0.74
96_S	100_Y	0.529	0.74
115_A	182_V	0.528	0.74
177_K	392_N	0.527	0.73
201_I	207_V	0.527	0.73
22_P	92_H	0.527	0.73
186_Y	274_E	0.527	0.73
268_M	272_L	0.525	0.73
112_V	259_A	0.523	0.73
144_L	177_K	0.522	0.73
373_I	379_F	0.522	0.73
330_K	342_I	0.522	0.73
17_A	20_S	0.521	0.73
180_K	204_V	0.520	0.73
374_Q	377_D	0.519	0.72
202_Q	207_V	0.518	0.72
125_K	396_E	0.517	0.72
100_Y	133_R	0.516	0.72
219_V	224_A	0.516	0.72
146_R	153_E	0.516	0.72
122_R	126_L	0.516	0.72
68_I	444_L	0.516	0.72
21_H	123_T	0.515	0.72
18_I	110_L	0.515	0.72
27_T	38_Q	0.515	0.72
297_T	380_T	0.515	0.72
74_V	87_L	0.515	0.72
298_G	379_F	0.514	0.72
149_R	153_E	0.514	0.72
39_A	354_S	0.512	0.71
204_V	207_V	0.512	0.71
73_S	439_G	0.512	0.71
216_D	226_Q	0.511	0.71
219_V	244_E	0.511	0.71
231_L	241_F	0.511	0.71
121_D	124_R	0.510	0.71
173_I	192_L	0.510	0.71
192_L	197_K	0.509	0.71
63_E	67_G	0.509	0.71
233_L	238_S	0.508	0.71
218_A	228_R	0.507	0.71
138_L	272_L	0.507	0.71
162_L	166_C	0.504	0.70
127_M	164_I	0.504	0.70
187_K	270_D	0.504	0.70
401_I	416_L	0.504	0.70
17_A	69_S	0.504	0.70
453_L	457_Y	0.503	0.70
419_L	459_V	0.502	0.70
219_V	223_L	0.501	0.70
450_V	461_A	0.500	0.70

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1darA	1	0.845	100	0.283	Contact Map
4kiyV	1	0.9622	100	0.284	Contact Map
2xexA	1	0.9527	100	0.294	Contact Map
4fn5A	1	0.9168	100	0.315	Contact Map
2dy1A	1	0.9395	100	0.333	Contact Map
3vqtA	2	0.9376	100	0.336	Contact Map
4w224	1	0.966	100	0.337	Contact Map
1n0uA	1	0.9282	100	0.347	Contact Map
2h5eA	1	0.9244	100	0.351	Contact Map
3j25A	1	0.896	100	0.356	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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