GREMLIN Database
RF3 - Peptide chain release factor 3
UniProt: P0A7I4 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12114
Length: 529 (479)
Sequences: 6963 (3284)
Seq/√Len: 150.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
359_A365_L6.2731.00
481_K496_D4.1611.00
140_F257_G3.8771.00
255_F271_G3.5801.00
226_Q237_A3.4441.00
140_F259_A3.4311.00
116_A146_R3.3901.00
479_A500_N3.3441.00
454_K460_E3.3251.00
326_E358_E3.1051.00
324_K358_E2.9551.00
404_K462_V2.9461.00
300_V316_A2.9371.00
114_D117_K2.9151.00
318_M367_L2.8811.00
285_D290_E2.8711.00
225_Q229_D2.8401.00
239_N274_E2.8331.00
314_R421_E2.7561.00
57_S75_M2.7501.00
113_I123_T2.6881.00
156_D160_N2.6741.00
30_T86_L2.6621.00
169_I255_F2.6571.00
234_V237_A2.6011.00
415_G453_L2.5681.00
404_K460_E2.5571.00
398_F439_G2.4691.00
296_F331_L2.4571.00
402_R462_V2.3901.00
425_V438_V2.2831.00
483_E494_A2.2431.00
320_V359_A2.2271.00
208_K211_N2.2211.00
189_E203_E2.2061.00
153_E157_E2.0721.00
139_T158_V2.0451.00
173_I190_T2.0331.00
46_V55_A2.0271.00
438_V449_V1.9981.00
124_R161_E1.9741.00
334_V380_T1.9611.00
59_W71_T1.9551.00
19_I111_M1.9531.00
154_L157_E1.9491.00
451_A455_S1.9421.00
167_A251_I1.9101.00
318_M365_L1.9101.00
191_Y267_H1.9031.00
194_Q202_Q1.8931.00
16_F84_V1.8891.00
187_K235_K1.8721.00
61_E65_Q1.8711.00
320_V365_L1.8501.00
222_D225_Q1.8121.00
481_K498_G1.7971.00
345_A367_L1.7951.00
483_E496_D1.7651.00
298_G318_M1.7651.00
370_H373_I1.7561.00
152_M213_P1.7531.00
394_A426_Q1.7531.00
61_E64_K1.7381.00
335_R377_D1.7201.00
220_G244_E1.7151.00
80_H274_E1.6991.00
330_K339_D1.6951.00
291_A294_D1.6941.00
17_A106_V1.6931.00
40_I56_K1.6901.00
336_T374_Q1.6861.00
19_I109_C1.6781.00
113_I158_V1.6661.00
402_R464_E1.6611.00
183_Y210_L1.6601.00
244_E248_A1.6591.00
405_D408_K1.6441.00
327_K357_E1.6381.00
399_R463_Y1.6161.00
80_H270_D1.6061.00
243_K247_L1.5981.00
115_A141_M1.5981.00
297_T387_F1.5911.00
477_A500_N1.5911.00
332_R337_A1.5891.00
233_L241_F1.5881.00
296_F320_V1.5841.00
347_T356_V1.5831.00
482_F495_L1.5801.00
30_T57_S1.5771.00
82_C273_V1.5641.00
331_L342_I1.5581.00
37_G77_F1.5461.00
398_F437_I1.5421.00
72_T87_L1.5391.00
15_T85_N1.5331.00
326_E329_M1.5171.00
29_I259_A1.5171.00
131_R137_I1.5161.00
450_V454_K1.5141.00
425_V449_V1.5111.00
78_P83_L1.5081.00
185_L188_D1.5051.00
29_I112_V1.4891.00
155_L168_P1.4881.00
77_F86_L1.4871.00
115_A144_L1.4851.00
78_P81_D1.4811.00
79_Y270_D1.4801.00
57_S73_S1.4791.00
18_I30_T1.4781.00
487_R492_Q1.4751.00
324_K360_Y1.4601.00
12_K82_C1.4561.00
420_S425_V1.4541.00
479_A498_G1.4531.00
233_L237_A1.4501.00
344_D355_H1.4381.00
138_L276_A1.4361.00
192_L204_V1.4361.00
189_E205_R1.4331.00
214_D217_A1.4321.00
482_F485_F1.4221.00
171_W210_L1.4211.00
126_L129_V1.4151.00
295_K381_Q1.4141.00
155_L254_V1.4131.00
12_K81_D1.4031.00
412_L453_L1.3951.00
75_M349_M1.3731.00
45_T48_G1.3601.00
428_F439_G1.3591.00
40_I43_A1.3541.00
114_D154_L1.3531.00
144_L175_C1.3491.00
108_C276_A1.3481.00
300_V373_I1.3471.00
224_A228_R1.3441.00
450_V463_Y1.3421.00
210_L213_P1.3351.00
356_V359_A1.3311.00
485_F492_Q1.3301.00
420_S438_V1.3211.00
226_Q231_L1.3111.00
338_K372_T1.3061.00
240_E244_E1.3041.00
57_S69_S1.2951.00
332_R339_D1.2921.00
111_M139_T1.2921.00
152_M156_D1.2901.00
65_Q455_S1.2831.00
59_W304_Q1.2781.00
173_I183_Y1.2611.00
188_D206_I1.2581.00
484_E491_S1.2481.00
214_D218_A1.2461.00
14_R279_P1.2461.00
62_M70_I1.2451.00
36_F266_D1.2371.00
97_E424_A1.2331.00
325_Y331_L1.2251.00
452_R456_E1.2171.00
314_R424_A1.2151.00
19_I103_L1.2121.00
270_D273_V1.2111.00
424_A427_V1.2041.00
221_E225_Q1.2001.00
216_D245_L1.1901.00
184_H187_K1.1891.00
482_F498_G1.1881.00
62_M451_A1.1871.00
180_K192_L1.1871.00
114_D146_R1.1821.00
80_H273_V1.1811.00
29_I268_M1.1751.00
226_Q234_V1.1741.00
130_T137_I1.1691.00
297_T322_S1.1681.00
216_D219_V1.1651.00
359_A363_D1.1641.00
487_R490_E1.1611.00
187_K203_E1.1601.00
325_Y342_I1.1491.00
157_E161_E1.1461.00
195_S199_H1.1461.00
114_D157_E1.1421.00
139_T252_T1.1321.00
77_F84_V1.1311.00
482_F496_D1.1291.00
20_S24_A1.1220.99
489_N492_Q1.1200.99
205_R208_K1.1180.99
239_N275_W1.1180.99
113_I139_T1.1160.99
303_I375_I1.1100.99
278_A281_P1.1100.99
111_M126_L1.1100.99
191_Y203_E1.1100.99
152_M171_W1.1090.99
430_P433_N1.1080.99
272_L276_A1.1080.99
87_L106_V1.1060.99
415_G419_L1.1050.99
243_K281_P1.1050.99
169_I271_G1.1030.99
340_V373_I1.0920.99
294_D322_S1.0890.99
142_N259_A1.0890.99
60_M71_T1.0870.99
100_Y132_L1.0820.99
315_V366_G1.0810.99
432_S471_A1.0800.99
488_K492_Q1.0770.99
123_T139_T1.0750.99
207_V211_N1.0660.99
119_V123_T1.0660.99
330_K341_V1.0640.99
144_L179_F1.0640.99
359_A367_L1.0640.99
486_K490_E1.0570.99
83_L363_D1.0550.99
488_K491_S1.0500.99
151_P168_P1.0500.99
300_V318_M1.0470.99
150_D153_E1.0440.99
402_R435_D1.0420.99
482_F486_K1.0400.99
141_M154_L1.0400.99
427_V436_L1.0390.99
490_E493_L1.0390.99
304_Q317_F1.0380.99
221_E250_E1.0370.99
66_R451_A1.0340.99
156_D159_E1.0270.99
318_M325_Y1.0260.99
220_G224_A1.0250.99
29_I265_V1.0230.99
408_K411_Q1.0220.99
111_M123_T1.0220.99
107_D319_R1.0220.99
485_F496_D1.0210.99
209_G212_N1.0120.99
173_I210_L1.0110.99
258_T261_G1.0100.99
187_K239_N1.0100.99
296_F325_Y1.0100.99
36_F262_N1.0090.99
346_L355_H1.0090.99
249_G252_T1.0090.99
420_S427_V1.0040.99
110_L268_M1.0040.99
424_A428_F1.0020.99
83_L347_T1.0020.99
61_E455_S0.9870.99
360_Y363_D0.9860.99
47_K55_A0.9840.99
333_Q336_T0.9820.99
117_K157_E0.9810.99
141_M254_V0.9770.99
301_F364_I0.9730.99
415_G459_V0.9690.98
109_C135_T0.9650.98
65_Q451_A0.9650.98
217_A241_F0.9640.98
190_T207_V0.9630.98
245_L251_I0.9580.98
308_D311_H0.9490.98
33_V77_F0.9380.98
215_L218_A0.9380.98
245_L250_E0.9380.98
333_Q373_I0.9360.98
119_V162_L0.9330.98
317_F348_F0.9280.98
59_W351_G0.9270.98
440_A446_F0.9200.98
435_D464_E0.9190.98
381_Q384_M0.9190.98
100_Y129_V0.9170.98
105_A301_F0.9160.98
28_T43_A0.9130.98
158_V254_V0.9070.98
216_D223_L0.9060.98
290_E294_D0.9060.98
292_S324_K0.9030.98
485_F488_K0.9020.98
198_G201_I0.9020.98
347_T354_S0.9020.98
132_L391_P0.9000.98
108_C277_P0.8930.97
97_E392_N0.8910.97
413_L436_L0.8890.97
76_Q83_L0.8850.97
320_V360_Y0.8850.97
348_F366_G0.8840.97
138_L271_G0.8800.97
222_D226_Q0.8800.97
110_L272_L0.8790.97
221_E224_A0.8790.97
495_L499_D0.8790.97
214_D221_E0.8770.97
20_S23_D0.8760.97
204_V208_K0.8740.97
55_A64_K0.8730.97
209_G213_P0.8710.97
285_D294_D0.8670.97
127_M137_I0.8630.97
70_I448_V0.8620.97
347_T359_A0.8610.97
206_I211_N0.8590.97
222_D237_A0.8550.97
235_K239_N0.8540.97
187_K191_Y0.8530.97
35_L43_A0.8510.97
114_D120_E0.8500.96
226_Q233_L0.8490.96
318_M359_A0.8490.96
31_E55_A0.8480.96
219_V241_F0.8440.96
205_R209_G0.8440.96
331_L379_F0.8430.96
28_T46_V0.8420.96
16_F272_L0.8410.96
242_D251_I0.8390.96
327_K355_H0.8380.96
292_S360_Y0.8360.96
487_R493_L0.8360.96
266_D270_D0.8330.96
483_E487_R0.8320.96
484_E487_R0.8320.96
158_V166_C0.8300.96
196_G199_H0.8300.96
45_T55_A0.8300.96
487_R491_S0.8290.96
40_I46_V0.8270.96
215_L220_G0.8270.96
485_F491_S0.8260.96
400_R435_D0.8260.96
13_R83_L0.8240.96
482_F491_S0.8220.96
271_G275_W0.8210.96
45_T54_H0.8180.96
217_A220_G0.8170.96
170_T256_F0.8170.96
483_E488_K0.8140.96
484_E495_L0.8130.95
485_F494_A0.8130.95
39_A349_M0.8110.95
218_A224_A0.8100.95
234_V238_S0.8090.95
356_V365_L0.8080.95
47_K260_L0.8060.95
346_L368_H0.8040.95
303_I316_A0.8040.95
85_N363_D0.8030.95
484_E493_L0.8020.95
340_V371_G0.7990.95
170_T182_V0.7990.95
236_G240_E0.7980.95
483_E495_L0.7980.95
203_E206_I0.7970.95
114_D143_K0.7960.95
486_K489_N0.7930.95
214_D220_G0.7900.95
380_T385_M0.7890.95
326_E357_E0.7850.95
159_E165_G0.7840.95
112_V142_N0.7830.94
216_D224_A0.7820.94
220_G223_L0.7820.94
488_K493_L0.7820.94
174_G179_F0.7810.94
339_D382_G0.7800.94
170_T184_H0.7760.94
138_L246_F0.7750.94
316_A373_I0.7740.94
441_V445_Q0.7690.94
217_A227_L0.7690.94
291_A295_K0.7680.94
107_D136_P0.7670.94
104_T390_I0.7650.94
84_V273_V0.7620.94
414_K418_Q0.7600.94
165_G215_L0.7580.93
169_I242_D0.7580.93
100_Y126_L0.7540.93
151_P256_F0.7540.93
218_A221_E0.7530.93
218_A223_L0.7520.93
208_K212_N0.7510.93
491_S494_A0.7510.93
443_V447_D0.7500.93
30_T75_M0.7490.93
153_E156_D0.7480.93
64_K351_G0.7470.93
309_P312_R0.7470.93
89_T99_T0.7450.93
141_M155_L0.7440.93
174_G180_K0.7420.93
226_Q230_E0.7410.93
486_K495_L0.7400.93
486_K492_Q0.7400.93
217_A221_E0.7380.93
188_D235_K0.7370.92
31_E44_G0.7370.92
207_V210_L0.7360.92
481_K484_E0.7360.92
192_L202_Q0.7350.92
217_A233_L0.7320.92
139_T254_V0.7280.92
217_A223_L0.7270.92
419_L453_L0.7270.92
115_A148_I0.7260.92
117_K120_E0.7250.92
170_T255_F0.7250.92
205_R211_N0.7250.92
480_K495_L0.7240.92
483_E491_S0.7230.92
217_A228_R0.7210.92
186_Y235_K0.7210.92
44_G54_H0.7200.92
435_D466_V0.7190.92
270_D274_E0.7190.92
42_T53_Q0.7170.91
486_K493_L0.7140.91
298_G325_Y0.7140.91
397_L443_V0.7130.91
423_G445_Q0.7090.91
218_A227_L0.7090.91
180_K209_G0.7070.91
487_R495_L0.7050.91
34_L56_K0.7020.91
297_T385_M0.7010.91
29_I33_V0.6990.90
68_I92_H0.6990.90
298_G367_L0.6990.90
17_A103_L0.6970.90
194_Q204_V0.6960.90
312_R346_L0.6950.90
412_L459_V0.6940.90
342_I367_L0.6930.90
19_I390_I0.6910.90
219_V245_L0.6910.90
104_T299_F0.6900.90
206_I210_L0.6890.90
193_Y201_I0.6890.90
257_G268_M0.6880.90
207_V212_N0.6870.90
13_R363_D0.6870.90
411_Q414_K0.6860.90
488_K495_L0.6850.89
399_R450_V0.6840.89
490_E494_A0.6830.89
242_D275_W0.6830.89
495_L498_G0.6820.89
33_V265_V0.6820.89
329_M381_Q0.6820.89
492_Q495_L0.6810.89
484_E489_N0.6810.89
117_K154_L0.6800.89
429_R434_N0.6790.89
299_F390_I0.6770.89
223_L241_F0.6760.89
74_V364_I0.6760.89
234_V240_E0.6760.89
489_N495_L0.6720.89
44_G53_Q0.6720.89
137_I249_G0.6710.89
223_L237_A0.6710.89
19_I126_L0.6710.89
72_T102_T0.6700.88
489_N493_L0.6700.88
220_G238_S0.6700.88
305_A314_R0.6700.88
99_T126_L0.6700.88
139_T154_L0.6700.88
43_A262_N0.6680.88
182_V267_H0.6670.88
482_F497_G0.6660.88
179_F182_V0.6620.88
141_M158_V0.6610.88
60_M452_R0.6590.88
174_G178_L0.6590.88
425_V428_F0.6590.88
167_A242_D0.6580.88
491_S496_D0.6560.87
37_G269_L0.6550.87
194_Q197_K0.6550.87
484_E496_D0.6550.87
225_Q228_R0.6540.87
144_L149_R0.6520.87
346_L353_R0.6520.87
202_Q206_I0.6510.87
58_D63_E0.6500.87
62_M65_Q0.6490.87
308_D312_R0.6480.87
481_K485_F0.6480.87
491_S495_L0.6470.87
321_V387_F0.6470.87
347_T363_D0.6460.87
93_E125_K0.6450.87
109_C130_T0.6450.87
223_L238_S0.6440.86
490_E495_L0.6430.86
440_A449_V0.6430.86
334_V386_K0.6420.86
92_H101_R0.6410.86
224_A227_L0.6400.86
223_L226_Q0.6400.86
145_D258_T0.6400.86
482_F493_L0.6400.86
345_A356_V0.6400.86
234_V241_F0.6370.86
141_M146_R0.6360.86
23_D68_I0.6360.86
173_I181_G0.6320.85
159_E166_C0.6310.85
330_K382_G0.6310.85
400_R464_E0.6310.85
294_D324_K0.6310.85
164_I252_T0.6300.85
20_S69_S0.6290.85
480_K496_D0.6290.85
332_R384_M0.6290.85
217_A230_E0.6290.85
317_F366_G0.6280.85
221_E228_R0.6270.85
481_K495_L0.6260.85
59_W350_A0.6250.85
19_I130_T0.6230.85
186_Y275_W0.6220.84
27_T34_L0.6220.84
298_G320_V0.6210.84
54_H64_K0.6210.84
408_K412_L0.6200.84
97_E389_G0.6180.84
33_V37_G0.6170.84
340_V370_H0.6160.84
214_D223_L0.6150.84
416_L420_S0.6150.84
47_K67_G0.6150.84
480_K497_G0.6140.84
126_L130_T0.6140.84
167_A170_T0.6140.84
103_L109_C0.6140.84
193_Y266_D0.6130.84
141_M168_P0.6130.84
483_E486_K0.6130.84
36_F198_G0.6130.84
104_T129_V0.6120.84
214_D224_A0.6120.84
238_S242_D0.6110.83
95_F448_V0.6110.83
71_T452_R0.6110.83
117_K146_R0.6100.83
215_L219_V0.6100.83
23_D143_K0.6100.83
399_R438_V0.6100.83
333_Q340_V0.6080.83
39_A75_M0.6080.83
305_A418_Q0.6070.83
55_A75_M0.6060.83
292_S361_P0.6060.83
220_G227_L0.6050.83
149_R157_E0.6040.83
332_R380_T0.6040.83
335_R386_K0.6030.83
344_D368_H0.6020.83
157_E160_N0.6010.82
482_F488_K0.6010.82
216_D238_S0.6000.82
174_G181_G0.5980.82
493_L497_G0.5980.82
202_Q212_N0.5980.82
414_K417_V0.5980.82
485_F489_N0.5970.82
171_W213_P0.5970.82
165_G250_E0.5970.82
65_Q456_E0.5960.82
483_E493_L0.5960.82
34_L75_M0.5960.82
296_F365_L0.5960.82
256_F445_Q0.5930.82
401_I463_Y0.5930.82
332_R382_G0.5910.81
428_F437_I0.5910.81
13_R85_N0.5910.81
214_D227_L0.5900.81
449_V453_L0.5890.81
484_E488_K0.5890.81
47_K57_S0.5870.81
346_L356_V0.5870.81
134_D249_G0.5860.81
476_C480_K0.5840.81
222_D229_D0.5830.80
108_C272_L0.5810.80
33_V269_L0.5810.80
293_E324_K0.5790.80
219_V250_E0.5780.80
35_L40_I0.5780.80
237_A240_E0.5780.80
374_Q421_E0.5770.80
333_Q377_D0.5770.80
487_R494_A0.5750.80
493_L499_D0.5740.79
105_A135_T0.5740.79
405_D460_E0.5740.79
151_P154_L0.5740.79
184_H189_E0.5730.79
410_K414_K0.5720.79
111_M137_I0.5720.79
437_I466_V0.5710.79
305_A421_E0.5710.79
483_E492_Q0.5710.79
111_M130_T0.5700.79
412_L416_L0.5690.79
217_A238_S0.5680.79
186_Y238_S0.5680.79
62_M66_R0.5670.79
332_R336_T0.5670.79
484_E492_Q0.5670.79
108_C246_F0.5660.79
231_L235_K0.5660.79
216_D228_R0.5660.79
216_D220_G0.5630.78
296_F324_K0.5610.78
29_I258_T0.5600.78
419_L457_Y0.5600.78
59_W73_S0.5590.78
37_G79_Y0.5580.78
73_S87_L0.5580.78
13_R314_R0.5580.78
112_V140_F0.5580.78
259_A265_V0.5570.77
236_G239_N0.5570.77
22_P69_S0.5560.77
170_T267_H0.5560.77
227_L230_E0.5560.77
48_G54_H0.5550.77
96_S441_V0.5540.77
177_K180_K0.5540.77
32_K36_F0.5530.77
188_D211_N0.5500.77
37_G86_L0.5500.77
191_Y201_I0.5490.76
482_F487_R0.5480.76
335_R373_I0.5460.76
419_L449_V0.5460.76
98_D302_K0.5450.76
284_T290_E0.5450.76
116_A260_L0.5440.76
140_F255_F0.5430.76
485_F493_L0.5420.76
114_D153_E0.5400.75
155_L166_C0.5380.75
303_I421_E0.5370.75
223_L233_L0.5360.75
285_D385_M0.5360.75
198_G266_D0.5350.75
149_R154_L0.5340.74
220_G228_R0.5340.74
29_I260_L0.5340.74
66_R448_V0.5330.74
23_D122_R0.5310.74
327_K344_D0.5300.74
170_T186_Y0.5300.74
181_G190_T0.5300.74
147_D177_K0.5290.74
96_S129_V0.5290.74
96_S100_Y0.5290.74
115_A182_V0.5280.74
177_K392_N0.5270.73
201_I207_V0.5270.73
22_P92_H0.5270.73
186_Y274_E0.5270.73
268_M272_L0.5250.73
112_V259_A0.5230.73
144_L177_K0.5220.73
373_I379_F0.5220.73
330_K342_I0.5220.73
17_A20_S0.5210.73
180_K204_V0.5200.73
374_Q377_D0.5190.72
202_Q207_V0.5180.72
125_K396_E0.5170.72
100_Y133_R0.5160.72
219_V224_A0.5160.72
146_R153_E0.5160.72
122_R126_L0.5160.72
68_I444_L0.5160.72
21_H123_T0.5150.72
18_I110_L0.5150.72
27_T38_Q0.5150.72
297_T380_T0.5150.72
74_V87_L0.5150.72
298_G379_F0.5140.72
149_R153_E0.5140.72
39_A354_S0.5120.71
204_V207_V0.5120.71
73_S439_G0.5120.71
216_D226_Q0.5110.71
219_V244_E0.5110.71
231_L241_F0.5110.71
121_D124_R0.5100.71
173_I192_L0.5100.71
192_L197_K0.5090.71
63_E67_G0.5090.71
233_L238_S0.5080.71
218_A228_R0.5070.71
138_L272_L0.5070.71
162_L166_C0.5040.70
127_M164_I0.5040.70
187_K270_D0.5040.70
401_I416_L0.5040.70
17_A69_S0.5040.70
453_L457_Y0.5030.70
419_L459_V0.5020.70
219_V223_L0.5010.70
450_V461_A0.5000.70
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1darA 1 0.845 100 0.283 Contact Map
4kiyV 1 0.9622 100 0.284 Contact Map
2xexA 1 0.9527 100 0.294 Contact Map
4fn5A 1 0.9168 100 0.315 Contact Map
2dy1A 1 0.9395 100 0.333 Contact Map
3vqtA 2 0.9376 100 0.336 Contact Map
4w224 1 0.966 100 0.337 Contact Map
1n0uA 1 0.9282 100 0.347 Contact Map
2h5eA 1 0.9244 100 0.351 Contact Map
3j25A 1 0.896 100 0.356 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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