GREMLIN Database
RECR - Recombination protein RecR
UniProt: P0A7H6 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10834
Length: 201 (193)
Sequences: 2895 (1632)
Seq/√Len: 117.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
80_N104_R4.5361.00
78_Q81_G4.3451.00
58_A67_E4.3051.00
81_G138_T3.4361.00
167_E198_K3.3031.00
49_R53_E3.3021.00
124_G127_R3.1611.00
20_V28_M3.1481.00
45_Q48_T2.6541.00
140_V161_C2.6011.00
132_L161_C2.5801.00
83_I137_I2.4731.00
58_A68_V2.4641.00
175_V184_V2.4471.00
113_S116_D2.3961.00
144_T154_A2.3951.00
14_L43_L2.3791.00
14_L29_A2.3261.00
24_S28_M2.3221.00
40_G47_L2.2691.00
37_R52_S2.2521.00
59_D68_V2.2441.00
61_R127_R2.2211.00
14_L32_L2.2041.00
55_G67_E2.1821.00
45_Q49_R1.9981.00
61_R124_G1.9771.00
41_M52_S1.8761.00
130_Q133_A1.8011.00
66_Q73_S1.7911.00
41_M48_T1.7641.00
119_G122_D1.7191.00
133_A164_Y1.6871.00
78_Q82_Q1.6801.00
37_R41_M1.6711.00
40_G51_M1.6681.00
125_L129_E1.6111.00
44_A48_T1.6071.00
125_L157_I1.5801.00
62_T92_I1.5561.00
36_D39_G1.5551.00
97_Q186_G1.4811.00
106_F131_R1.4801.00
56_H109_M1.4021.00
169_S196_R1.4021.00
9_Q49_R1.4001.00
78_Q138_T1.3911.00
169_S198_K1.3671.00
141_I193_L1.3581.00
111_H145_N1.3471.00
87_E111_H1.3391.00
191_H194_A1.3221.00
109_M124_G1.3101.00
41_M45_Q1.3081.00
8_T12_E1.2851.00
6_L65_E1.2630.99
130_Q134_E1.2610.99
111_H147_T1.2590.99
126_D130_Q1.2430.99
59_D135_E1.2400.99
96_E105_Y1.2080.99
59_D134_E1.1780.99
7_L54_I1.1690.99
123_I157_I1.1650.99
71_I92_I1.1580.99
10_L50_A1.1540.99
13_A42_R1.1530.99
132_L136_K1.1390.99
13_A16_C1.1290.99
176_P179_G1.1210.99
95_I193_L1.1190.99
16_C39_G1.1190.99
173_H191_H1.1160.99
11_M26_Q1.1150.99
32_L35_R1.1010.98
9_Q42_R1.0970.98
98_T190_S1.0970.98
129_E160_L1.0910.98
48_T52_S1.0890.98
160_L163_Q1.0740.98
80_N136_K1.0680.98
161_C168_A1.0620.98
54_I63_F1.0530.98
37_R51_M1.0420.98
101_F104_R1.0350.98
74_N102_S1.0330.98
5_P9_Q1.0290.98
60_C72_C1.0160.97
64_T68_V1.0100.97
38_S41_M1.0010.97
92_I107_V0.9990.97
82_Q138_T0.9970.97
59_D80_N0.9960.97
81_G134_E0.9890.97
62_T89_P0.9780.97
142_L168_A0.9740.97
59_D131_R0.9670.97
144_T170_R0.9640.96
185_D188_T0.9640.96
22_P179_G0.9540.96
40_G43_L0.9410.96
39_G42_R0.9370.96
34_Q88_S0.9140.95
13_A46_A0.9090.95
132_L166_V0.9080.95
84_C103_G0.9070.95
53_E65_E0.8950.95
30_F93_Y0.8900.95
151_E155_N0.8640.94
17_L28_M0.8590.93
129_E133_A0.8580.93
89_P92_I0.8570.93
89_P109_M0.8520.93
91_D179_G0.8510.93
59_D106_F0.8470.93
55_G64_T0.8460.93
111_H144_T0.8430.93
11_M141_I0.8360.92
71_I77_R0.8330.92
69_C72_C0.8320.92
35_R39_G0.8320.92
66_Q70_N0.8270.92
84_C101_F0.8240.92
60_C69_C0.8230.92
7_L29_A0.8210.92
68_V73_S0.8190.92
6_L53_E0.8160.92
191_H195_G0.8110.91
83_I134_E0.8080.91
6_L46_A0.8010.91
55_G58_A0.7990.91
75_P80_N0.7790.90
6_L49_R0.7770.89
142_L154_A0.7710.89
111_H118_I0.7700.89
125_L160_L0.7690.89
13_A39_G0.7650.89
20_V25_A0.7640.89
120_P123_I0.7620.89
30_F195_G0.7610.88
133_A136_K0.7590.88
112_L148_V0.7540.88
132_L157_I0.7500.88
98_T193_L0.7490.88
120_P156_Y0.7460.87
104_R131_R0.7450.87
41_M44_A0.7370.87
61_R109_M0.7360.87
106_F123_I0.7280.86
180_E183_M0.7270.86
40_G44_A0.7260.86
176_P188_T0.7210.86
155_N187_T0.7200.86
22_P175_V0.7190.86
29_A50_A0.7180.85
106_F127_R0.7170.85
129_E161_C0.7120.85
156_Y160_L0.7100.85
30_F89_P0.7090.85
59_D127_R0.7090.85
55_G68_V0.7080.85
129_E132_L0.7050.84
151_E191_H0.7050.84
41_M51_M0.7040.84
6_L54_I0.7030.84
15_R22_P0.7020.84
45_Q73_S0.6970.84
80_N135_E0.6950.84
170_R173_H0.6940.83
61_R173_H0.6900.83
148_V173_H0.6900.83
5_P70_N0.6890.83
139_E196_R0.6860.83
84_C95_I0.6830.82
143_A171_I0.6740.82
23_K197_H0.6720.81
83_I104_R0.6700.81
14_L20_V0.6650.81
82_Q101_F0.6610.80
13_A43_L0.6610.80
8_T22_P0.6570.80
78_Q104_R0.6560.80
121_D126_D0.6530.80
76_R102_S0.6510.79
112_L152_A0.6500.79
34_Q115_L0.6460.79
92_I146_P0.6460.79
82_Q167_E0.6450.79
127_R130_Q0.6450.79
138_T167_E0.6430.79
26_Q192_S0.6420.78
110_G153_T0.6410.78
91_D111_H0.6410.78
165_D198_K0.6400.78
133_A163_Q0.6390.78
30_F63_F0.6370.78
77_R96_E0.6360.78
126_D160_L0.6350.78
184_V195_G0.6330.77
78_Q102_S0.6210.76
179_G188_T0.6210.76
33_L50_A0.6200.76
88_S94_A0.6190.76
59_D62_T0.6170.76
90_A112_L0.6170.76
110_G123_I0.6150.75
100_Q193_L0.6140.75
100_Q194_A0.6140.75
11_M30_F0.6070.74
23_K180_E0.6070.74
129_E164_Y0.6030.74
17_L21_G0.5990.74
83_I106_F0.5950.73
118_I122_D0.5950.73
12_E42_R0.5920.73
42_R45_Q0.5920.73
21_G25_A0.5880.72
97_Q106_F0.5820.71
92_I190_S0.5800.71
130_Q162_A0.5790.71
46_A49_R0.5790.71
171_I183_M0.5770.71
36_D160_L0.5760.71
92_I95_I0.5740.70
70_N166_V0.5740.70
73_S85_V0.5730.70
91_D94_A0.5730.70
172_A196_R0.5720.70
111_H171_I0.5700.70
31_T35_R0.5700.70
176_P185_D0.5690.70
61_R180_E0.5680.70
114_P119_G0.5680.70
177_V197_H0.5670.69
84_C193_L0.5630.69
35_R40_G0.5610.69
59_D104_R0.5610.69
106_F156_Y0.5580.68
81_G104_R0.5570.68
110_G131_R0.5570.68
84_C143_A0.5530.68
49_R52_S0.5520.67
155_N159_E0.5510.67
119_G152_A0.5500.67
117_G147_T0.5500.67
95_I189_L0.5480.67
165_D168_A0.5480.67
173_H177_V0.5470.67
21_G27_R0.5460.67
178_G196_R0.5460.67
55_G66_Q0.5460.67
12_E15_R0.5450.66
88_S92_I0.5440.66
43_L176_P0.5430.66
88_S145_N0.5400.66
70_N102_S0.5400.66
23_K179_G0.5390.66
191_H197_H0.5380.65
82_Q102_S0.5360.65
186_G189_L0.5360.65
30_F109_M0.5330.65
74_N77_R0.5320.65
73_S134_E0.5320.65
101_F141_I0.5320.65
93_Y97_Q0.5300.64
155_N195_G0.5270.64
64_T73_S0.5270.64
131_R135_E0.5240.63
83_I143_A0.5240.63
144_T150_G0.5230.63
18_P25_A0.5190.63
30_F90_A0.5160.62
14_L33_L0.5160.62
75_P104_R0.5120.62
26_Q182_E0.5100.61
7_L13_A0.5100.61
10_L14_L0.5100.61
7_L115_L0.5090.61
71_I189_L0.5080.61
61_R106_F0.5080.61
18_P21_G0.5080.61
13_A95_I0.5080.61
171_I197_H0.5070.61
34_Q90_A0.5060.61
93_Y173_H0.5040.60
186_G190_S0.5020.60
129_E157_I0.5010.60
7_L67_E0.5000.60
140_V168_A0.5000.60
161_C187_T0.5000.60
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3vdpA 2 0.9851 100 0.065 Contact Map
1vddA 7 0.9851 100 0.086 Contact Map
2gaiA 1 0.5274 96.9 0.905 Contact Map
1mw9X 1 0.5373 96.8 0.906 Contact Map
4dduA 1 0.8756 95.7 0.915 Contact Map
1gkuB 1 0.8209 95.5 0.917 Contact Map
1i7dA 1 0.7015 95.2 0.918 Contact Map
4cgyA 1 0.6219 94.5 0.921 Contact Map
2fcjA 2 0.5423 93.8 0.924 Contact Map
1yuzA 2 0.393 84.7 0.937 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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