GREMLIN Database
PYRG - CTP synthase
UniProt: P0A7E5 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10810
Length: 545 (528)
Sequences: 2974 (1285)
Seq/√Len: 55.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
457_L531_G4.6771.00
366_R370_E4.5541.00
293_G344_L4.1561.00
291_T324_N4.0111.00
365_A384_V3.7791.00
289_E324_N3.7381.00
291_T326_K3.7311.00
398_N410_Y3.6781.00
372_N507_P3.6261.00
165_G168_H3.5021.00
292_I346_A3.3721.00
25_L260_I3.2661.00
326_K344_L3.2071.00
454_V500_I3.1751.00
443_A464_V3.0801.00
365_A375_Y3.0521.00
365_A509_F2.9601.00
252_K257_D2.8101.00
170_L207_I2.8061.00
453_L456_Q2.7891.00
479_K483_D2.6981.00
363_T366_R2.6751.00
347_I368_A2.6501.00
452_S487_R2.6471.00
408_C411_P2.6461.00
384_V387_I2.6221.00
246_K284_A2.5791.00
326_K343_G2.5781.00
372_N505_N2.5551.00
316_G323_V2.5431.00
389_Y393_V2.5201.00
321_V537_S2.4681.00
396_M480_Q2.4251.00
34_L136_V2.4101.00
375_Y385_A2.3731.00
21_A209_I2.3511.00
450_D455_R2.3431.00
500_I514_F2.3391.00
124_K163_E2.3361.00
455_R461_P2.3291.00
334_E337_G2.3121.00
242_D246_K2.3011.00
197_E200_S2.2981.00
487_R504_P2.2721.00
207_I256_L2.2711.00
233_K262_K2.2651.00
396_M410_Y2.2541.00
181_A213_D2.2471.00
171_F203_I2.2341.00
454_V489_A2.2171.00
394_A481_I2.1981.00
121_N125_E2.1861.00
97_S101_R2.1761.00
81_R524_D2.1641.00
398_N409_K2.1541.00
319_N534_K2.1371.00
218_A222_A2.1131.00
293_G328_I2.1071.00
288_S321_V2.0841.00
401_S404_F2.0641.00
410_Y477_L2.0641.00
453_L510_V1.9881.00
402_T411_P1.9731.00
452_S489_A1.9701.00
160_M164_I1.9571.00
99_V119_I1.9541.00
508_W532_F1.9391.00
249_G277_E1.9081.00
492_S495_D1.9061.00
481_I486_L1.8721.00
400_N405_V1.8640.99
309_I327_L1.8640.99
385_A509_F1.8590.99
222_A232_E1.8580.99
56_Q111_A1.8490.99
98_D122_A1.8480.99
358_V384_V1.8180.99
450_D461_P1.8140.99
64_E443_A1.8140.99
449_V482_E1.8100.99
349_V375_Y1.8060.99
86_R94_R1.7940.99
457_L510_V1.7860.99
473_V481_I1.7750.99
30_E81_R1.7570.99
287_V320_R1.7420.99
64_E83_K1.7380.99
289_E322_S1.7140.99
386_L412_V1.7140.99
396_M477_L1.7110.99
534_K538_E1.7000.99
359_E362_I1.6700.99
122_A125_E1.6460.99
242_D284_A1.6380.99
479_K482_E1.6380.99
375_Y384_V1.6070.98
278_Q282_E1.6040.98
372_N506_H1.6000.98
492_S496_Q1.5940.98
380_L404_F1.5790.98
376_L532_F1.5700.98
15_S183_S1.5660.98
177_V216_V1.5620.98
99_V108_Y1.5610.98
508_W531_G1.5520.98
288_S537_S1.5470.98
175_T191_T1.5390.98
348_L532_F1.5240.98
31_A273_L1.5210.98
282_E320_R1.5190.98
480_Q483_D1.5130.98
394_A480_Q1.5110.98
478_L491_R1.5100.98
454_V510_V1.5060.98
136_V264_F1.4890.97
413_V473_V1.4870.97
30_E82_T1.4850.97
445_Q462_T1.4750.97
346_A532_F1.4610.97
358_V404_F1.4520.97
473_V478_L1.4500.97
398_N405_V1.4440.97
162_V229_N1.4390.97
446_C514_F1.4340.97
457_L508_W1.4330.97
386_L501_I1.4320.97
449_V487_R1.4320.97
4_N168_H1.4280.97
358_V380_L1.4260.97
22_A138_L1.4230.97
154_L201_I1.4220.97
396_M409_K1.4130.97
173_H194_S1.4090.96
443_A519_T1.4040.96
208_L224_I1.3800.96
446_C490_G1.3730.96
519_T526_H1.3700.96
234_A259_Y1.3690.96
382_M501_I1.3680.96
448_L454_V1.3650.96
98_D126_R1.3620.96
389_Y484_A1.3530.96
419_W432_K1.3460.95
333_V364_T1.3440.95
238_L251_L1.3440.95
170_L263_R1.3440.95
236_I259_Y1.3440.95
475_N478_L1.3430.95
237_S254_Q1.3430.95
37_T88_N1.3370.95
102_K107_D1.3280.95
45_I92_T1.3270.95
329_D332_D1.3160.95
333_V340_I1.3120.95
365_A388_D1.3010.94
382_M473_V1.3010.94
25_L172_M1.2990.94
294_M308_V1.2980.94
400_N408_C1.2940.94
167_E265_S1.2930.94
38_I80_I1.2920.94
388_D392_H1.2910.94
64_E519_T1.2910.94
445_Q464_V1.2900.94
386_L473_V1.2880.94
318_K525_G1.2830.94
291_T344_L1.2800.94
448_L452_S1.2770.94
8_V138_L1.2760.94
255_G258_D1.2680.94
163_E171_F1.2610.93
39_M139_V1.2550.93
486_L501_I1.2500.93
45_I119_I1.2460.93
196_K200_S1.2390.93
385_A511_A1.2360.93
291_T343_G1.2260.92
141_I157_I1.2250.92
414_A419_W1.2250.92
504_P507_P1.2140.92
241_V250_L1.2140.92
27_A30_E1.2130.92
453_L508_W1.2120.92
447_Q462_T1.2080.92
5_Y129_E1.2080.92
333_V337_G1.2060.92
55_I300_E1.2030.92
346_A536_A1.2020.92
83_K521_T1.1990.92
92_T119_I1.1910.91
212_S237_S1.1910.91
127_V160_M1.1850.91
451_D456_Q1.1830.91
206_D263_R1.1830.91
109_L435_L1.1800.91
292_I536_A1.1780.91
394_A484_A1.1750.91
488_V491_R1.1740.91
157_I171_F1.1720.91
402_T408_C1.1680.91
475_N498_V1.1590.90
283_E317_L1.1580.90
448_L490_G1.1510.90
94_R126_R1.1500.90
366_R392_H1.1460.90
375_Y509_F1.1430.90
96_Y115_V1.1390.89
21_A174_L1.1390.89
186_V217_P1.1380.89
447_Q461_P1.1350.89
41_L49_P1.1340.89
4_N264_F1.1320.89
41_L139_V1.1310.89
243_S284_A1.1210.89
503_V506_H1.1200.89
281_F285_N1.1180.89
300_E329_D1.1160.88
347_I373_I1.1140.88
98_D102_K1.1130.88
491_R495_D1.1120.88
217_P220_E1.1110.88
457_L532_F1.1070.88
20_I247_I1.1060.88
161_A169_T1.1040.88
199_L229_N1.1030.88
6_I170_L1.1010.88
480_Q484_A1.0970.88
212_S239_K1.0960.88
81_R521_T1.0950.87
339_E342_K1.0900.87
348_L378_I1.0860.87
349_V385_A1.0840.87
259_Y263_R1.0790.87
451_D455_R1.0790.87
170_L260_I1.0780.87
417_T496_Q1.0700.86
21_A238_L1.0690.86
385_A501_I1.0650.86
337_G363_T1.0610.86
386_L481_I1.0570.86
312_L323_V1.0560.85
397_E410_Y1.0560.85
405_V408_C1.0520.85
41_L127_V1.0500.85
136_V266_L1.0490.85
488_V498_V1.0450.85
41_L75_H1.0440.85
249_G280_I1.0440.85
34_L268_C1.0430.85
348_L361_M1.0420.85
258_D262_K1.0370.84
414_A417_T1.0360.84
286_P320_R1.0300.84
161_A171_F1.0250.84
172_M260_I1.0250.84
295_V330_S1.0180.83
333_V363_T1.0180.83
27_A31_A1.0170.83
154_L203_I1.0150.83
376_L510_V1.0120.83
243_S280_I1.0080.83
389_Y486_L1.0050.83
464_V519_T1.0040.82
359_E391_R0.9960.82
246_K280_I0.9860.81
348_L368_A0.9810.81
21_A251_L0.9810.81
454_V512_C0.9790.81
195_V205_P0.9790.81
243_S283_E0.9790.81
218_A232_E0.9780.81
224_I235_V0.9780.81
338_V371_N0.9780.81
410_Y480_Q0.9760.81
328_I344_L0.9740.81
334_E363_T0.9740.81
365_A387_I0.9720.80
445_Q493_G0.9710.80
341_L344_L0.9710.80
257_D271_A0.9700.80
302_P327_L0.9630.80
199_L204_Q0.9610.80
390_A481_I0.9600.80
9_T173_H0.9580.79
37_T137_V0.9570.79
90_F126_R0.9570.79
415_L419_W0.9530.79
308_V378_I0.9530.79
129_E137_V0.9520.79
293_G326_K0.9490.79
279_V317_L0.9490.79
448_L455_R0.9470.79
402_T414_A0.9450.78
326_K340_I0.9440.78
308_V351_G0.9430.78
531_G534_K0.9430.78
482_E488_V0.9420.78
145_V154_L0.9400.78
335_T363_T0.9340.78
161_A166_R0.9310.77
53_S56_Q0.9290.77
122_A126_R0.9290.77
369_R388_D0.9260.77
164_I168_H0.9260.77
449_V452_S0.9200.77
386_L486_L0.9150.76
253_S277_E0.9150.76
315_G530_A0.9110.76
30_E80_I0.9070.76
129_E132_E0.9070.76
181_A214_R0.9030.75
155_E158_R0.9000.75
166_R206_D0.8960.75
337_G341_L0.8930.74
315_G319_N0.8930.74
380_L401_S0.8920.74
38_I88_N0.8920.74
96_Y152_P0.8900.74
34_L261_C0.8890.74
39_M49_P0.8820.73
115_V119_I0.8820.73
252_K271_A0.8790.73
84_M88_N0.8790.73
277_E281_F0.8730.73
99_V154_L0.8710.73
49_P75_H0.8710.73
82_T521_T0.8710.73
303_D308_V0.8690.72
109_L439_M0.8680.72
178_P191_T0.8680.72
215_A239_K0.8670.72
210_C224_I0.8640.72
311_A315_G0.8600.72
455_R459_N0.8600.72
382_M512_C0.8570.71
316_G533_V0.8560.71
136_V261_C0.8550.71
101_R434_D0.8540.71
416_I419_W0.8530.71
262_K265_S0.8530.71
294_M309_I0.8530.71
445_Q492_S0.8510.71
212_S216_V0.8430.70
27_A523_R0.8420.70
503_V509_F0.8410.70
35_N133_G0.8400.70
394_A486_L0.8390.70
389_Y503_V0.8340.69
191_T224_I0.8300.69
215_A237_S0.8290.69
90_F303_D0.8290.69
372_N504_P0.8280.69
45_I99_V0.8280.69
31_A271_A0.8270.69
175_T178_P0.8260.68
105_R434_D0.8260.68
233_K259_Y0.8240.68
241_V247_I0.8230.68
16_L21_A0.8170.68
209_I238_L0.8170.68
342_K367_F0.8160.68
261_C268_C0.8150.67
500_I512_C0.8150.67
306_K313_K0.8140.67
32_R257_D0.8140.67
453_L457_L0.8140.67
256_L260_I0.8100.67
129_E134_H0.8090.67
488_V501_I0.8070.67
463_I526_H0.8060.67
34_L135_D0.8000.66
477_L480_Q0.7950.66
161_A229_N0.7940.65
41_L90_F0.7940.65
319_N533_V0.7890.65
95_I126_R0.7870.65
414_A430_S0.7860.65
288_S320_R0.7860.65
39_M88_N0.7820.64
293_G345_D0.7810.64
465_E526_H0.7780.64
342_K371_N0.7770.64
315_G323_V0.7770.64
447_Q493_G0.7760.64
397_E409_K0.7760.64
186_V220_E0.7750.64
328_I333_V0.7750.64
343_G373_I0.7740.63
67_A86_R0.7700.63
207_I259_Y0.7690.63
200_S492_S0.7680.63
157_I169_T0.7670.63
250_L253_S0.7670.63
367_F371_N0.7660.63
387_I400_N0.7650.63
315_G533_V0.7640.62
179_Y183_S0.7620.62
419_W430_S0.7610.62
507_P539_F0.7600.62
467_H499_E0.7570.62
365_A385_A0.7560.62
362_I384_V0.7520.61
64_E464_V0.7520.61
63_T69_T0.7500.61
16_L174_L0.7500.61
61_F83_K0.7490.61
116_I120_T0.7410.60
221_R254_Q0.7410.60
454_V511_A0.7390.60
63_T67_A0.7380.60
238_L254_Q0.7370.60
182_A225_A0.7370.60
525_G530_A0.7370.60
361_M384_V0.7310.59
39_M138_L0.7300.59
275_E523_R0.7290.59
347_I532_F0.7280.59
64_E518_F0.7280.59
345_D540_Q0.7280.59
216_V220_E0.7280.59
98_D101_R0.7270.59
368_A375_Y0.7260.58
410_Y476_M0.7250.58
445_Q494_D0.7230.58
447_Q495_D0.7220.58
452_S490_G0.7210.58
264_F269_P0.7190.58
89_N109_L0.7190.58
34_L267_N0.7190.58
501_I511_A0.7180.58
208_L230_V0.7180.58
418_E439_M0.7170.58
280_I284_A0.7160.57
196_K199_L0.7150.57
531_G535_A0.7140.57
52_M60_V0.7140.57
489_A503_V0.7130.57
234_A263_R0.7120.57
491_R498_V0.7120.57
348_L385_A0.7110.57
120_T159_Q0.7110.57
291_T345_D0.7100.57
61_F521_T0.7100.57
346_A376_L0.7090.57
161_A206_D0.7080.57
225_A231_P0.7080.57
364_T368_A0.7070.56
15_S238_L0.7070.56
295_V349_V0.7070.56
183_S240_D0.7060.56
446_C454_V0.7050.56
124_K159_Q0.7040.56
186_V214_R0.7040.56
396_M408_C0.7020.56
83_K443_A0.7010.56
115_V148_I0.7000.56
130_G133_G0.6980.56
55_I61_F0.6960.55
231_P263_R0.6950.55
308_V350_P0.6950.55
221_R237_S0.6930.55
366_R371_N0.6930.55
180_M183_S0.6900.55
252_K270_E0.6860.54
359_E400_N0.6840.54
288_S540_Q0.6830.54
164_I169_T0.6820.54
394_A398_N0.6810.54
389_Y481_I0.6800.54
114_Q149_E0.6800.54
167_E263_R0.6790.53
333_V338_V0.6780.53
9_T194_S0.6760.53
404_F408_C0.6760.53
358_V387_I0.6740.53
207_I254_Q0.6740.53
128_L134_H0.6730.53
39_M90_F0.6730.53
490_G500_I0.6690.52
47_V52_M0.6690.52
451_D487_R0.6680.52
95_I122_A0.6670.52
34_L266_L0.6660.52
394_A482_E0.6660.52
315_G318_K0.6650.52
32_R261_C0.6650.52
177_V237_S0.6650.52
49_P179_Y0.6630.52
101_R105_R0.6620.52
338_V342_K0.6610.52
94_R98_D0.6600.51
26_A138_L0.6590.51
16_L176_L0.6580.51
302_P309_I0.6580.51
286_P322_S0.6560.51
246_K281_F0.6550.51
229_N234_A0.6540.51
376_L531_G0.6540.51
290_V536_A0.6540.51
446_C500_I0.6540.51
453_L505_N0.6530.51
392_H397_E0.6520.51
368_A385_A0.6510.50
530_A534_K0.6500.50
301_L304_A0.6490.50
67_A94_R0.6480.50
275_E278_Q0.6460.50
37_T80_I0.6460.50
121_N222_A0.6450.50
478_L498_V0.6450.50
279_V523_R0.6440.50
418_E435_L0.6430.50
332_D340_I0.6430.50
378_I512_C0.6430.50
85_S88_N0.6400.49
210_C439_M0.6400.49
331_Q356_R0.6400.49
308_V419_W0.6390.49
207_I234_A0.6370.49
257_D261_C0.6360.49
152_P193_H0.6360.49
521_T524_D0.6350.49
81_R523_R0.6330.48
436_G441_L0.6310.48
473_V498_V0.6290.48
380_L384_V0.6280.48
510_V528_L0.6280.48
362_I392_H0.6280.48
362_I365_A0.6270.48
396_M400_N0.6260.48
25_L256_L0.6230.47
358_V400_N0.6230.47
386_L389_Y0.6220.47
45_I327_L0.6220.47
115_V152_P0.6220.47
446_C497_L0.6220.47
141_I154_L0.6220.47
246_K249_G0.6210.47
61_F80_I0.6210.47
102_K122_A0.6190.47
279_V283_E0.6180.47
319_N537_S0.6180.47
37_T134_H0.6170.47
247_I254_Q0.6160.47
107_D111_A0.6150.47
489_A500_I0.6150.47
8_V38_I0.6150.47
194_S198_L0.6150.47
312_L325_I0.6140.46
102_K125_E0.6140.46
473_V500_I0.6140.46
30_E521_T0.6140.46
355_Y404_F0.6140.46
169_T203_I0.6130.46
358_V401_S0.6120.46
87_R94_R0.6110.46
362_I366_R0.6110.46
418_E430_S0.6100.46
514_F526_H0.6100.46
116_I416_I0.6090.46
389_Y394_A0.6080.46
165_G387_I0.6080.46
292_I533_V0.6070.46
258_D268_C0.6070.46
348_L512_C0.6070.46
105_R435_L0.6070.46
15_S188_T0.6060.46
131_G134_H0.6060.46
100_L247_I0.6060.46
207_I260_I0.6040.45
312_L348_L0.6030.45
448_L500_I0.6030.45
316_G321_V0.6030.45
450_D460_A0.6020.45
184_G240_D0.6010.45
382_M514_F0.6000.45
182_A240_D0.6000.45
457_L530_A0.5990.45
274_S277_E0.5980.45
45_I115_V0.5970.45
73_L94_R0.5970.45
239_K250_L0.5960.44
336_R339_E0.5960.44
501_I509_F0.5950.44
36_V479_K0.5950.44
510_V531_G0.5940.44
318_K530_A0.5940.44
337_G340_I0.5930.44
436_G472_E0.5920.44
449_V489_A0.5900.44
302_P308_V0.5890.44
25_L209_I0.5890.44
15_S161_A0.5880.44
8_V24_S0.5880.44
41_L94_R0.5880.44
444_Q492_S0.5880.44
526_H529_F0.5870.44
384_V404_F0.5870.44
419_W433_S0.5860.43
7_F157_I0.5850.43
400_N404_F0.5850.43
261_C266_L0.5850.43
39_M75_H0.5840.43
416_I439_M0.5830.43
478_L488_V0.5820.43
282_E318_K0.5820.43
304_A384_V0.5820.43
193_H197_E0.5810.43
348_L364_T0.5800.43
186_V212_S0.5790.43
71_L112_T0.5790.43
454_V528_L0.5780.43
161_A204_Q0.5780.43
30_E83_K0.5780.43
219_N222_A0.5750.42
293_G368_A0.5750.42
348_L533_V0.5750.42
180_M237_S0.5740.42
338_V373_I0.5740.42
435_L439_M0.5740.42
172_M328_I0.5730.42
193_H196_K0.5730.42
56_Q350_P0.5690.42
508_W528_L0.5690.42
231_P234_A0.5690.42
243_S317_L0.5680.42
89_N92_T0.5680.42
371_N450_D0.5680.42
295_V364_T0.5680.42
503_V510_V0.5680.42
136_V268_C0.5680.42
116_I345_D0.5670.41
450_D487_R0.5670.41
21_A325_I0.5670.41
49_P139_V0.5660.41
512_C518_F0.5660.41
41_L126_R0.5650.41
378_I529_F0.5650.41
518_F522_P0.5650.41
444_Q497_L0.5650.41
120_T227_F0.5640.41
417_T430_S0.5640.41
328_I341_L0.5630.41
34_L251_L0.5620.41
449_V491_R0.5610.41
388_D509_F0.5600.41
376_L512_C0.5600.41
127_V157_I0.5590.41
382_M511_A0.5550.40
164_I171_F0.5550.40
47_V100_L0.5540.40
313_K317_L0.5540.40
102_K126_R0.5540.40
13_V180_M0.5540.40
3_T137_V0.5540.40
37_T53_S0.5540.40
196_K204_Q0.5520.40
301_L376_L0.5520.40
278_Q397_E0.5520.40
419_W431_E0.5500.40
89_N102_K0.5500.40
228_C490_G0.5500.40
16_L164_I0.5490.40
415_L432_K0.5490.40
484_A503_V0.5490.40
315_G511_A0.5490.40
503_V507_P0.5490.40
169_T301_L0.5480.39
537_S540_Q0.5470.39
361_M463_I0.5470.39
145_V241_V0.5450.39
351_G404_F0.5450.39
400_N411_P0.5450.39
314_H520_S0.5440.39
177_V210_C0.5430.39
444_Q493_G0.5420.39
29_L260_I0.5410.39
261_C267_N0.5410.39
126_R417_T0.5410.39
376_L511_A0.5400.39
309_I313_K0.5390.38
382_M500_I0.5380.38
30_E306_K0.5380.38
206_D262_K0.5380.38
294_M344_L0.5370.38
97_S100_L0.5370.38
148_I235_V0.5370.38
67_A186_V0.5370.38
330_S511_A0.5350.38
224_I237_S0.5350.38
473_V514_F0.5350.38
242_D392_H0.5340.38
121_N212_S0.5340.38
487_R503_V0.5340.38
38_I85_S0.5340.38
127_V137_V0.5340.38
290_V538_E0.5330.38
124_K229_N0.5320.38
177_V240_D0.5320.38
166_R231_P0.5310.38
521_T525_G0.5300.38
292_I378_I0.5300.38
396_M402_T0.5300.38
366_R388_D0.5300.38
454_V514_F0.5300.38
52_M56_Q0.5290.37
204_Q229_N0.5290.37
273_L277_E0.5290.37
21_A306_K0.5280.37
486_L503_V0.5280.37
98_D125_E0.5280.37
158_R176_L0.5280.37
329_D384_V0.5270.37
506_H529_F0.5270.37
115_V125_E0.5260.37
416_I519_T0.5260.37
56_Q60_V0.5260.37
184_G301_L0.5260.37
308_V317_L0.5250.37
198_L203_I0.5250.37
106_G147_D0.5250.37
4_N136_V0.5250.37
258_D261_C0.5240.37
15_S257_D0.5240.37
279_V351_G0.5240.37
398_N480_Q0.5240.37
73_L112_T0.5230.37
236_I255_G0.5230.37
453_L504_P0.5230.37
244_I334_E0.5230.37
241_V246_K0.5230.37
347_I367_F0.5230.37
67_A176_L0.5220.37
355_Y358_V0.5210.37
491_R494_D0.5210.37
335_T366_R0.5210.37
342_K366_R0.5210.37
201_I225_A0.5210.37
90_F145_V0.5210.37
393_V481_I0.5200.37
446_C463_I0.5200.37
116_I175_T0.5200.37
16_L183_S0.5180.36
96_Y119_I0.5180.36
311_A512_C0.5180.36
21_A27_A0.5180.36
447_Q494_D0.5170.36
394_A504_P0.5170.36
473_V477_L0.5170.36
63_T75_H0.5160.36
126_R161_A0.5160.36
536_A539_F0.5160.36
319_N530_A0.5160.36
174_L229_N0.5160.36
278_Q281_F0.5160.36
472_E497_L0.5150.36
147_D159_Q0.5150.36
45_I100_L0.5140.36
38_I82_T0.5130.36
51_T437_G0.5130.36
6_I452_S0.5130.36
460_A538_E0.5120.36
41_L92_T0.5120.36
161_A457_L0.5110.36
339_E484_A0.5100.36
370_E388_D0.5090.35
417_T498_V0.5090.35
119_I152_P0.5090.35
111_A492_S0.5090.35
167_E290_V0.5090.35
88_N306_K0.5090.35
61_F177_V0.5090.35
106_G114_Q0.5080.35
319_N508_W0.5070.35
45_I86_R0.5060.35
20_I294_M0.5060.35
366_R480_Q0.5060.35
455_R500_I0.5050.35
348_L376_L0.5050.35
139_V160_M0.5040.35
49_P183_S0.5020.35
43_P112_T0.5020.35
75_H179_Y0.5020.35
34_L257_D0.5020.35
210_C375_Y0.5020.35
316_G319_N0.5010.35
36_V80_I0.5010.35
135_D283_E0.5010.35
475_N497_L0.5010.35
371_N483_D0.5010.35
304_A510_V0.5000.35
308_V529_F0.5000.35
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4zdjA 4 0.9596 100 0.398 Contact Map
3nvaA 2 0.9651 100 0.422 Contact Map
1vcoA 4 0.9596 100 0.452 Contact Map
2vo1A 4 0.4165 100 0.479 Contact Map
1s1mA 4 0.9835 100 0.507 Contact Map
2v4uA 1 0.4532 100 0.785 Contact Map
2w7tA 1 0.4477 100 0.812 Contact Map
1l9xA 1 0.4165 100 0.897 Contact Map
4l8fC 3 0.411 100 0.898 Contact Map
3uowA 2 0.4018 99.9 0.901 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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