PURA - ECOLI - GREMLIN Contacts

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PURA - Adenylosuccinate synthetase

UniProt:	P0A7D4	Sequences: MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAEKLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLDVLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10790
Length:	432 (421)
Sequences:	3013 (1511)
Seq/√Len:	73.7

ECOLI - PURA
BACSU - PURA
HALSA - PURA
SULSO - Q980P5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
341_E	375_T	6.163	1.00
349_R	370_E	5.881	1.00
54_H	301_T	5.368	1.00
340_K	380_S	4.309	1.00
85_K	197_I	3.682	1.00
394_Q	398_N	3.634	1.00
388_D	391_G	3.610	1.00
52_V	300_A	3.369	1.00
374_E	402_R	3.314	1.00
352_D	368_G	3.297	1.00
49_E	90_R	3.170	1.00
389_R	397_L	3.052	1.00
330_L	400_I	3.028	1.00
402_R	406_L	2.990	1.00
289_E	293_K	2.950	1.00
292_C	305_R	2.929	1.00
85_K	89_D	2.784	1.00
78_A	190_D	2.727	1.00
290_F	339_L	2.700	1.00
341_E	377_P	2.677	1.00
311_L	316_V	2.656	1.00
395_A	398_N	2.640	1.00
93_P	96_E	2.584	1.00
344_L	402_R	2.539	1.00
313_T	406_L	2.529	1.00
343_K	375_T	2.526	1.00
262_Y	327_G	2.465	1.00
183_D	186_K	2.432	1.00
116_N	131_G	2.419	1.00
290_F	294_Q	2.416	1.00
344_L	376_M	2.405	1.00
338_G	381_E	2.379	1.00
29_K	217_D	2.357	1.00
159_A	163_K	2.313	1.00
30_Y	212_A	2.294	1.00
76_S	112_V	2.291	1.00
349_R	355_E	2.273	1.00
106_L	149_V	2.250	1.00
389_R	401_K	2.197	1.00
110_Y	165_V	2.169	1.00
337_D	383_T	2.162	1.00
293_K	298_F	2.138	1.00
126_A	276_A	2.114	1.00
328_F	407_T	2.095	1.00
174_V	181_A	2.081	1.00
211_Q	215_R	2.069	1.00
228_L	315_A	2.055	1.00
185_Q	189_D	2.050	1.00
350_M	369_V	2.046	1.00
153_F	202_V	2.003	1.00
32_V	253_S	1.999	1.00
350_M	356_V	1.978	1.00
75_L	104_C	1.964	1.00
69_I	73_V	1.958	1.00
377_P	395_A	1.952	1.00
327_G	412_D	1.935	1.00
402_R	405_E	1.901	1.00
394_Q	397_L	1.889	1.00
397_L	401_K	1.857	1.00
99_L	203_V	1.851	1.00
99_L	208_L	1.831	1.00
350_M	368_G	1.825	1.00
376_M	402_R	1.804	1.00
344_L	406_L	1.790	1.00
81_M	197_I	1.776	1.00
214_Q	408_G	1.756	1.00
184_Y	188_L	1.729	1.00
10_T	325_L	1.712	1.00
338_G	380_S	1.665	1.00
381_E	395_A	1.665	1.00
85_K	88_E	1.662	1.00
75_L	80_L	1.651	1.00
398_N	401_K	1.638	1.00
347_A	355_E	1.634	1.00
311_L	403_I	1.632	1.00
196_D	199_T	1.601	0.99
75_L	149_V	1.583	0.99
186_K	190_D	1.580	0.99
401_K	426_L	1.571	0.99
294_Q	338_G	1.567	0.99
377_P	398_N	1.564	0.99
69_I	75_L	1.558	0.99
158_F	162_L	1.556	0.99
292_C	298_F	1.553	0.99
149_V	202_V	1.552	0.99
386_V	391_G	1.550	0.99
38_H	76_S	1.542	0.99
404_E	426_L	1.533	0.99
66_T	99_L	1.532	0.99
48_G	419_D	1.525	0.99
162_L	184_Y	1.523	0.99
163_K	184_Y	1.499	0.99
78_A	194_V	1.498	0.99
387_K	391_G	1.497	0.99
153_F	199_T	1.496	0.99
401_K	404_E	1.495	0.99
46_I	61_L	1.491	0.99
159_A	188_L	1.490	0.99
213_R	219_V	1.488	0.99
158_F	191_T	1.480	0.99
38_H	107_I	1.474	0.99
105_P	146_G	1.474	0.99
350_M	365_D	1.469	0.99
80_L	84_M	1.463	0.99
210_D	214_Q	1.459	0.99
38_H	79_A	1.459	0.99
155_K	192_M	1.455	0.99
389_R	426_L	1.446	0.99
345_C	371_P	1.435	0.99
288_G	308_T	1.427	0.99
337_D	382_S	1.410	0.99
400_I	411_I	1.400	0.99
104_C	149_V	1.399	0.98
6_V	249_V	1.394	0.98
320_V	325_L	1.391	0.98
203_V	208_L	1.382	0.98
401_K	405_E	1.375	0.98
346_V	355_E	1.369	0.98
68_I	205_V	1.358	0.98
285_D	288_G	1.353	0.98
71_N	233_H	1.344	0.98
139_E	143_A	1.339	0.98
227_T	323_N	1.337	0.98
267_L	316_V	1.330	0.98
80_L	98_L	1.326	0.98
221_F	255_L	1.319	0.98
188_L	192_M	1.301	0.98
284_F	287_T	1.284	0.97
362_A	365_D	1.280	0.97
77_P	198_L	1.280	0.97
78_A	82_K	1.275	0.97
320_V	409_V	1.273	0.97
30_Y	209_L	1.271	0.97
120_K	179_A	1.263	0.97
189_D	193_A	1.263	0.97
387_K	421_T	1.262	0.97
283_L	288_G	1.261	0.97
212_A	217_D	1.260	0.97
258_R	326_S	1.257	0.97
374_E	406_L	1.248	0.97
313_T	402_R	1.221	0.96
343_K	373_Y	1.220	0.96
159_A	184_Y	1.197	0.96
350_M	354_R	1.191	0.96
30_Y	208_L	1.185	0.96
355_E	370_E	1.177	0.96
416_T	422_E	1.165	0.95
387_K	422_E	1.164	0.95
4_N	221_F	1.160	0.95
210_D	259_Y	1.157	0.95
31_V	65_V	1.150	0.95
210_D	321_Q	1.146	0.95
34_Y	244_T	1.145	0.95
22_D	420_R	1.140	0.95
258_R	324_S	1.139	0.95
159_A	185_Q	1.137	0.95
117_A	173_L	1.131	0.95
155_K	159_A	1.127	0.94
337_D	381_E	1.125	0.94
314_V	347_A	1.125	0.94
403_I	411_I	1.125	0.94
154_D	364_D	1.121	0.94
162_L	188_L	1.115	0.94
86_E	89_D	1.113	0.94
313_T	344_L	1.112	0.94
120_K	131_G	1.100	0.94
384_F	422_E	1.097	0.94
66_T	208_L	1.094	0.93
256_G	324_S	1.093	0.93
157_T	161_K	1.091	0.93
346_V	374_E	1.091	0.93
214_Q	259_Y	1.090	0.93
81_M	198_L	1.083	0.93
113_A	116_N	1.082	0.93
103_A	361_L	1.081	0.93
163_K	167_E	1.080	0.93
147_L	158_F	1.078	0.93
206_S	321_Q	1.075	0.93
207_D	321_Q	1.071	0.93
289_E	305_R	1.065	0.93
359_T	366_W	1.061	0.92
337_D	380_S	1.059	0.92
227_T	319_A	1.054	0.92
102_E	361_L	1.051	0.92
9_G	15_E	1.050	0.92
243_N	251_T	1.050	0.92
209_L	219_V	1.042	0.92
189_D	192_M	1.030	0.91
26_E	62_R	1.028	0.91
207_D	211_Q	1.026	0.91
349_R	353_G	1.022	0.91
108_L	191_T	1.021	0.91
286_E	289_E	1.018	0.91
171_F	176_Y	1.018	0.91
319_A	323_N	1.013	0.91
100_L	149_V	1.003	0.90
355_E	372_I	0.999	0.90
117_A	179_A	0.996	0.90
75_L	100_L	0.993	0.90
376_M	398_N	0.985	0.89
290_F	293_K	0.979	0.89
4_N	213_R	0.977	0.89
191_T	194_V	0.977	0.89
289_E	292_C	0.976	0.89
414_I	424_M	0.968	0.88
293_K	296_N	0.966	0.88
313_T	316_V	0.964	0.88
212_A	215_R	0.958	0.88
205_V	208_L	0.956	0.88
271_S	315_A	0.955	0.88
311_L	407_T	0.953	0.88
166_M	170_N	0.953	0.88
141_K	232_D	0.951	0.88
386_V	389_R	0.945	0.87
182_V	187_V	0.940	0.87
404_E	411_I	0.929	0.86
209_L	253_S	0.928	0.86
195_A	199_T	0.926	0.86
213_R	255_L	0.923	0.86
282_E	307_R	0.923	0.86
313_T	403_I	0.923	0.86
250_A	257_P	0.920	0.86
225_Q	229_L	0.916	0.86
349_R	352_D	0.916	0.86
125_K	238_Y	0.912	0.85
262_Y	412_D	0.911	0.85
160_E	164_E	0.906	0.85
265_G	325_L	0.894	0.84
159_A	192_M	0.890	0.84
107_I	137_A	0.889	0.84
272_T	332_K	0.885	0.84
291_L	331_T	0.885	0.84
262_Y	326_S	0.885	0.84
113_A	182_V	0.882	0.83
333_L	396_A	0.879	0.83
228_L	318_R	0.879	0.83
139_E	145_R	0.876	0.83
63_E	97_R	0.874	0.83
125_K	160_E	0.872	0.83
199_T	202_V	0.871	0.83
365_D	368_G	0.868	0.82
68_I	208_L	0.866	0.82
193_A	196_D	0.864	0.82
287_T	339_L	0.860	0.82
229_L	273_R	0.857	0.81
385_G	416_T	0.855	0.81
349_R	354_R	0.851	0.81
113_A	179_A	0.849	0.81
387_K	416_T	0.845	0.81
6_V	260_V	0.844	0.80
413_I	423_T	0.844	0.80
287_T	290_F	0.843	0.80
86_E	90_R	0.843	0.80
129_T	135_G	0.841	0.80
247_G	251_T	0.836	0.80
281_T	373_Y	0.835	0.80
109_D	190_D	0.832	0.80
207_D	358_T	0.831	0.79
166_M	182_V	0.831	0.79
88_E	93_P	0.831	0.79
122_R	164_E	0.829	0.79
384_F	416_T	0.829	0.79
211_Q	357_T	0.828	0.79
419_D	422_E	0.827	0.79
43_T	50_K	0.823	0.79
47_N	421_T	0.818	0.78
50_K	296_N	0.814	0.78
221_F	253_S	0.808	0.78
382_S	416_T	0.808	0.78
80_L	201_M	0.805	0.77
400_I	414_I	0.804	0.77
191_T	195_A	0.804	0.77
87_L	92_I	0.803	0.77
30_Y	66_T	0.803	0.77
64_N	93_P	0.802	0.77
206_S	233_H	0.801	0.77
45_V	50_K	0.801	0.77
175_N	178_K	0.799	0.77
20_I	413_I	0.799	0.77
245_T	248_G	0.795	0.76
150_G	361_L	0.794	0.76
101_S	205_V	0.793	0.76
316_V	407_T	0.793	0.76
171_F	175_N	0.790	0.76
88_E	197_I	0.790	0.76
349_R	372_I	0.790	0.76
34_Y	248_G	0.790	0.76
298_F	305_R	0.789	0.76
205_V	209_L	0.788	0.76
7_V	28_A	0.788	0.76
366_W	369_V	0.784	0.75
149_V	198_L	0.782	0.75
142_V	231_I	0.781	0.75
68_I	203_V	0.779	0.75
155_K	188_L	0.777	0.75
245_T	251_T	0.777	0.75
283_L	287_T	0.776	0.75
327_G	410_P	0.772	0.74
286_E	290_F	0.772	0.74
400_I	404_E	0.772	0.74
56_I	226_G	0.772	0.74
76_S	79_A	0.771	0.74
417_G	422_E	0.770	0.74
389_R	400_I	0.769	0.74
105_P	137_A	0.769	0.74
141_K	148_R	0.769	0.74
400_I	426_L	0.769	0.74
193_A	197_I	0.767	0.74
77_P	81_M	0.766	0.74
71_N	252_G	0.765	0.74
82_K	86_E	0.764	0.73
398_N	405_E	0.763	0.73
156_E	160_E	0.762	0.73
29_K	218_F	0.762	0.73
356_V	369_V	0.760	0.73
247_G	256_G	0.759	0.73
382_S	385_G	0.759	0.73
50_K	300_A	0.758	0.73
267_L	328_F	0.757	0.73
113_A	117_A	0.756	0.73
55_L	73_V	0.755	0.73
291_L	332_K	0.755	0.73
318_R	321_Q	0.753	0.72
54_H	86_E	0.750	0.72
117_A	131_G	0.747	0.72
71_N	243_N	0.746	0.72
224_A	229_L	0.745	0.72
317_R	406_L	0.745	0.72
56_I	87_L	0.745	0.72
356_V	365_D	0.745	0.72
267_L	330_L	0.738	0.71
192_M	195_A	0.738	0.71
270_Y	335_V	0.735	0.71
147_L	165_V	0.733	0.70
84_M	94_V	0.732	0.70
338_G	342_V	0.731	0.70
350_M	353_G	0.730	0.70
386_V	397_L	0.727	0.70
342_V	380_S	0.724	0.69
33_R	224_A	0.723	0.69
390_S	397_L	0.723	0.69
347_A	372_I	0.722	0.69
219_V	255_L	0.721	0.69
235_T	273_R	0.721	0.69
225_Q	273_R	0.720	0.69
246_A	250_A	0.720	0.69
294_Q	339_L	0.719	0.69
332_K	335_V	0.719	0.69
35_Q	226_G	0.718	0.69
355_E	374_E	0.717	0.69
325_L	409_V	0.716	0.69
30_Y	68_I	0.716	0.69
112_V	116_N	0.715	0.68
88_E	94_V	0.714	0.68
339_L	342_V	0.713	0.68
102_E	202_V	0.710	0.68
74_V	138_Y	0.709	0.68
140_D	169_H	0.708	0.68
342_V	399_Y	0.708	0.68
329_C	413_I	0.705	0.67
79_A	107_I	0.704	0.67
8_L	249_V	0.701	0.67
113_A	131_G	0.700	0.67
54_H	79_A	0.700	0.67
293_K	305_R	0.699	0.67
63_E	93_P	0.699	0.67
272_T	308_T	0.697	0.67
102_E	150_G	0.697	0.67
60_I	67_S	0.697	0.67
364_D	367_K	0.695	0.66
110_Y	169_H	0.693	0.66
81_M	85_K	0.692	0.66
382_S	422_E	0.691	0.66
376_M	406_L	0.690	0.66
81_M	84_M	0.689	0.66
283_L	308_T	0.686	0.65
51_T	90_R	0.685	0.65
81_M	194_V	0.684	0.65
317_R	357_T	0.684	0.65
10_T	267_L	0.683	0.65
135_G	144_R	0.681	0.65
221_F	249_V	0.678	0.64
363_A	367_K	0.677	0.64
374_E	398_N	0.675	0.64
190_D	193_A	0.675	0.64
295_G	335_V	0.675	0.64
69_I	80_L	0.674	0.64
287_T	291_L	0.669	0.63
62_R	65_V	0.669	0.63
5_V	28_A	0.669	0.63
48_G	421_T	0.666	0.63
166_M	184_Y	0.666	0.63
376_M	395_A	0.665	0.63
224_A	273_R	0.664	0.63
4_N	255_L	0.663	0.63
93_P	97_R	0.662	0.63
192_M	196_D	0.658	0.62
150_G	362_A	0.655	0.62
248_G	252_G	0.655	0.62
113_A	173_L	0.654	0.62
161_K	164_E	0.654	0.62
118_R	139_E	0.653	0.61
186_K	189_D	0.652	0.61
35_Q	244_T	0.650	0.61
5_V	264_L	0.648	0.61
347_A	357_T	0.648	0.61
229_L	235_T	0.647	0.61
10_T	265_G	0.646	0.61
67_S	300_A	0.646	0.61
129_T	239_V	0.646	0.61
290_F	338_G	0.645	0.61
213_R	259_Y	0.645	0.61
82_K	85_K	0.641	0.60
38_H	416_T	0.641	0.60
228_L	359_T	0.640	0.60
311_L	406_L	0.640	0.60
8_L	246_A	0.638	0.60
103_A	150_G	0.638	0.60
68_I	209_L	0.637	0.60
207_D	357_T	0.636	0.59
170_N	181_A	0.635	0.59
413_I	425_I	0.635	0.59
170_N	182_V	0.634	0.59
263_V	325_L	0.632	0.59
81_M	100_L	0.632	0.59
52_V	67_S	0.631	0.59
146_G	236_Y	0.631	0.59
38_H	292_C	0.630	0.59
30_Y	219_V	0.628	0.58
235_T	271_S	0.628	0.58
295_G	308_T	0.628	0.58
105_P	148_R	0.627	0.58
123_G	276_A	0.624	0.58
170_N	177_Y	0.623	0.58
30_Y	217_D	0.623	0.58
21_V	267_L	0.623	0.58
102_E	204_D	0.622	0.58
264_L	327_G	0.622	0.58
34_Y	415_S	0.621	0.58
56_I	60_I	0.621	0.58
328_F	400_I	0.620	0.58
286_E	340_K	0.619	0.57
60_I	98_L	0.618	0.57
364_D	368_G	0.617	0.57
151_D	161_K	0.614	0.57
190_D	194_V	0.612	0.57
32_V	70_G	0.611	0.56
102_E	362_A	0.607	0.56
194_V	198_L	0.606	0.56
129_T	144_R	0.606	0.56
328_F	403_I	0.604	0.56
407_T	411_I	0.603	0.55
112_V	190_D	0.602	0.55
111_H	140_D	0.600	0.55
291_L	342_V	0.597	0.55
342_V	376_M	0.596	0.55
53_L	60_I	0.596	0.55
127_I	144_R	0.596	0.55
383_T	396_A	0.594	0.54
210_D	256_G	0.594	0.54
114_L	173_L	0.594	0.54
71_N	232_D	0.594	0.54
346_V	349_R	0.592	0.54
70_G	252_G	0.592	0.54
82_K	89_D	0.592	0.54
374_E	377_P	0.592	0.54
345_C	373_Y	0.591	0.54
320_V	407_T	0.591	0.54
35_Q	111_H	0.591	0.54
20_I	415_S	0.588	0.54
23_L	415_S	0.588	0.54
156_E	159_A	0.588	0.54
392_L	396_A	0.587	0.53
157_T	160_E	0.586	0.53
84_M	201_M	0.586	0.53
344_L	403_I	0.586	0.53
54_H	82_K	0.584	0.53
309_G	312_D	0.584	0.53
163_K	189_D	0.584	0.53
208_L	212_A	0.583	0.53
78_A	191_T	0.583	0.53
180_E	183_D	0.583	0.53
117_A	120_K	0.583	0.53
337_D	416_T	0.583	0.53
415_S	423_T	0.581	0.53
51_T	300_A	0.581	0.53
344_L	405_E	0.580	0.53
238_Y	276_A	0.580	0.53
164_E	167_E	0.580	0.53
399_Y	403_I	0.579	0.52
411_I	414_I	0.579	0.52
344_L	374_E	0.578	0.52
25_T	28_A	0.577	0.52
394_Q	401_K	0.577	0.52
173_L	179_A	0.576	0.52
60_I	92_I	0.576	0.52
111_H	223_G	0.575	0.52
337_D	384_F	0.575	0.52
38_H	169_H	0.574	0.52
35_Q	53_L	0.574	0.52
416_T	423_T	0.574	0.52
149_V	199_T	0.573	0.52
7_V	122_R	0.571	0.51
260_V	263_V	0.569	0.51
11_Q	144_R	0.569	0.51
150_G	202_V	0.568	0.51
183_D	192_M	0.568	0.51
311_L	344_L	0.568	0.51
56_I	279_F	0.565	0.51
313_T	407_T	0.563	0.50
102_E	153_F	0.563	0.50
168_Y	172_Q	0.563	0.50
121_A	171_F	0.563	0.50
274_V	304_R	0.562	0.50
111_H	137_A	0.561	0.50
132_R	301_T	0.561	0.50
20_I	329_C	0.561	0.50
142_V	145_R	0.561	0.50
154_D	362_A	0.560	0.50
112_V	132_R	0.559	0.50
13_G	17_K	0.558	0.50
10_T	226_G	0.558	0.50
341_E	398_N	0.557	0.50
232_D	243_N	0.557	0.50
44_L	51_T	0.556	0.50
352_D	365_D	0.556	0.50
122_R	367_K	0.556	0.50
25_T	62_R	0.555	0.49
126_A	131_G	0.553	0.49
270_Y	295_G	0.553	0.49
10_T	316_V	0.550	0.49
68_I	99_L	0.550	0.49
118_R	168_Y	0.550	0.49
213_R	290_F	0.548	0.49
130_T	136_P	0.548	0.49
71_N	101_S	0.548	0.49
167_E	171_F	0.547	0.48
54_H	300_A	0.547	0.48
268_K	297_E	0.547	0.48
314_V	359_T	0.546	0.48
157_T	364_D	0.546	0.48
281_T	345_C	0.545	0.48
109_D	187_V	0.545	0.48
170_N	174_V	0.543	0.48
207_D	210_D	0.541	0.48
296_N	305_R	0.541	0.48
37_G	42_H	0.540	0.48
6_V	246_A	0.540	0.48
274_V	302_T	0.539	0.47
383_T	416_T	0.539	0.47
54_H	132_R	0.538	0.47
153_F	195_A	0.537	0.47
46_I	49_E	0.537	0.47
45_V	419_D	0.535	0.47
64_N	97_R	0.535	0.47
9_G	13_G	0.534	0.47
226_G	415_S	0.533	0.47
156_E	355_E	0.532	0.47
332_K	336_L	0.531	0.46
44_L	52_V	0.531	0.46
393_P	396_A	0.531	0.46
349_R	374_E	0.531	0.46
78_A	193_A	0.530	0.46
68_I	150_G	0.528	0.46
396_A	416_T	0.528	0.46
66_T	217_D	0.527	0.46
108_L	165_V	0.527	0.46
155_K	195_A	0.525	0.46
352_D	362_A	0.525	0.46
386_V	426_L	0.525	0.46
26_E	397_L	0.524	0.46
283_L	310_W	0.524	0.46
44_L	53_L	0.524	0.46
7_V	79_A	0.524	0.46
145_R	168_Y	0.523	0.46
398_N	402_R	0.523	0.46
38_H	112_V	0.523	0.46
106_L	147_L	0.522	0.45
20_I	23_L	0.522	0.45
354_R	370_E	0.522	0.45
135_G	273_R	0.520	0.45
44_L	245_T	0.520	0.45
389_R	414_I	0.518	0.45
268_K	274_V	0.518	0.45
245_T	250_A	0.517	0.45
211_Q	358_T	0.516	0.45
405_E	408_G	0.516	0.45
116_N	120_K	0.516	0.45
33_R	111_H	0.516	0.45
328_F	411_I	0.515	0.45
297_E	304_R	0.515	0.45
208_L	211_Q	0.515	0.45
32_V	209_L	0.514	0.44
125_K	164_E	0.513	0.44
386_V	405_E	0.513	0.44
5_V	262_Y	0.512	0.44
162_L	187_V	0.512	0.44
248_G	251_T	0.511	0.44
122_R	145_R	0.511	0.44
113_A	180_E	0.511	0.44
77_P	225_Q	0.510	0.44
272_T	331_T	0.510	0.44
147_L	151_D	0.509	0.44
157_T	365_D	0.508	0.44
21_V	31_V	0.508	0.44
349_R	368_G	0.508	0.44
62_R	139_E	0.508	0.44
255_L	259_Y	0.507	0.44
7_V	24_L	0.507	0.44
174_V	177_Y	0.507	0.44
11_Q	135_G	0.507	0.44
404_E	410_P	0.507	0.44
250_A	260_V	0.507	0.44
117_A	178_K	0.506	0.43
38_H	123_G	0.506	0.43
365_D	369_V	0.506	0.43
211_Q	214_Q	0.505	0.43
44_L	50_K	0.505	0.43
77_P	194_V	0.505	0.43
201_M	330_L	0.505	0.43
235_T	272_T	0.505	0.43
315_A	325_L	0.504	0.43
174_V	180_E	0.503	0.43
35_Q	223_G	0.503	0.43
224_A	235_T	0.503	0.43
250_A	253_S	0.502	0.43
330_L	403_I	0.502	0.43
245_T	359_T	0.502	0.43
337_D	342_V	0.501	0.43
55_L	74_V	0.500	0.43
388_D	424_M	0.500	0.43
250_A	255_L	0.500	0.43

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3hidA	2	0.9815	100	0.003	Contact Map
4m9dA	2	0.9931	100	0.006	Contact Map
3ue9A	2	0.9722	100	0.012	Contact Map
2v40A	2	0.956	100	0.026	Contact Map
1dj2A	2	0.9815	100	0.027	Contact Map
3r7tA	4	0.9444	100	0.029	Contact Map
1p9bA	2	0.9699	100	0.03	Contact Map
2d7uA	2	0.7384	100	0.208	Contact Map
1f8mA	4	0.6227	34.6	0.981	Contact Map
2a3lA	3	0.1644	14.6	0.984	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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