GREMLIN Database
PPK - Polyphosphate kinase
UniProt: P0A7B1 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11510
Length: 688 (665)
Sequences: 2497 (1506)
Seq/√Len: 58.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
356_L441_I6.5591.00
502_Y629_L5.9561.00
525_A531_S5.5311.00
560_N581_R5.1671.00
520_R605_K4.7871.00
548_R551_A4.4161.00
524_N529_L4.3411.00
519_D548_R4.2311.00
535_L613_W3.6371.00
515_Y548_R3.3681.00
655_D661_R3.3271.00
58_K286_D3.2581.00
606_V638_L3.0801.00
608_L626_T3.0771.00
119_Q195_P3.0481.00
455_I626_T2.9901.00
122_W186_P2.9881.00
532_G560_N2.9341.00
331_N359_Q2.9171.00
519_D551_A2.9051.00
362_F388_H2.9041.00
453_A481_T2.8701.00
221_N269_P2.8201.00
343_L474_L2.7931.00
125_H129_Q2.7901.00
162_I218_D2.7771.00
522_I548_R2.7771.00
26_A90_E2.7701.00
599_E604_K2.7531.00
511_R619_D2.7041.00
558_P579_N2.6891.00
573_L576_I2.6601.00
6_L576_I2.6431.00
520_R600_N2.6391.00
517_M605_K2.5751.00
655_D659_S2.5751.00
71_S79_K2.5491.00
336_I476_A2.5351.00
628_L637_V2.5311.00
475_T480_I2.4921.00
583_I651_A2.4241.00
50_Y288_I2.4001.00
558_P581_R2.3781.00
587_D672_R2.3781.00
519_D522_I2.3271.00
398_V423_V2.3161.00
514_L545_L2.3081.00
596_Y613_W2.3071.00
643_I671_V2.3051.00
40_G301_I2.2911.00
521_E600_N2.2891.00
581_R653_Y2.2831.00
19_E90_E2.2731.00
604_K638_L2.2611.00
116_S119_Q2.2521.00
16_S83_R2.2511.00
331_N334_D2.2361.00
545_L618_I2.2251.00
513_L517_M2.2011.00
37_R301_I2.2001.00
54_F80_I2.1951.00
506_S510_S2.1901.00
183_V202_I2.1861.00
522_I526_Q2.1771.00
597_I641_I2.1701.00
336_I474_L2.1551.00
342_L633_L2.1461.00
532_G558_P2.1431.00
523_A527_Q2.1331.00
356_L474_L2.1291.00
671_V676_A2.1261.00
335_A341_V2.1221.00
609_S625_A2.1031.00
356_L439_F2.0931.00
438_L484_V2.0921.00
524_N599_E2.0801.00
519_D523_A2.0621.00
553_S577_S2.0541.00
273_V289_V2.0531.00
562_L645_F2.0511.00
184_N194_K2.0491.00
337_R450_V2.0391.00
90_E93_G2.0381.00
513_L516_E1.9911.00
339_R632_R1.9871.00
16_S19_E1.9801.00
455_I608_L1.9651.00
646_S671_V1.9621.00
27_D650_K1.9471.00
7_Y547_D1.9451.00
23_Q652_R1.9411.00
639_D680_Y1.9381.00
357_L439_F1.9021.00
123_L202_I1.8931.00
162_I220_L1.8671.00
534_T645_F1.8541.00
672_R675_L1.8501.00
511_R542_D1.8421.00
644_L673_A1.8361.00
270_N274_E1.8301.00
524_N600_N1.8291.00
534_T641_I1.8291.00
324_F474_L1.8260.99
541_V568_S1.8100.99
26_A94_L1.8090.99
316_L678_Y1.8020.99
550_Y577_S1.7970.99
535_L561_L1.7910.99
445_E452_Y1.7890.99
504_M513_L1.7800.99
103_A108_F1.7760.99
337_R445_E1.7640.99
324_F341_V1.7570.99
532_G599_E1.7530.99
477_D629_L1.7480.99
511_R544_G1.7470.99
529_L601_G1.7160.99
105_N308_K1.7040.99
101_E104_R1.6970.99
518_V533_I1.6940.99
128_K209_D1.6930.99
37_R313_N1.6920.99
453_A484_V1.6750.99
676_A679_D1.6690.99
531_S599_E1.6680.99
277_R287_S1.6650.99
124_R209_D1.6530.99
530_P599_E1.6420.99
675_L679_D1.6240.99
342_L473_L1.6180.99
266_R291_G1.6140.99
24_E650_K1.6130.99
6_L547_D1.6050.99
520_R524_N1.5950.99
522_I551_A1.5950.99
377_A462_E1.5940.99
600_N604_K1.5940.99
57_L76_L1.5860.99
471_Y640_I1.5840.99
355_E359_Q1.5810.99
81_Q85_L1.5730.98
105_N310_N1.5510.98
83_R86_K1.5350.98
42_Y87_A1.5270.98
540_L569_L1.5260.98
525_A528_G1.5250.98
43_S91_F1.5210.98
354_L462_E1.5160.98
95_Y99_L1.5050.98
438_L487_V1.4790.98
537_L613_W1.4640.98
521_E602_G1.4640.98
455_I480_I1.4490.97
174_I203_L1.4450.97
204_R265_Q1.4410.97
522_I525_A1.4270.97
174_I199_L1.4250.97
463_K467_L1.4250.97
101_E105_N1.4220.97
313_N588_R1.4210.97
534_T562_L1.4180.97
593_D644_L1.4160.97
357_L382_I1.4140.97
130_Y444_K1.4100.97
575_G578_D1.4090.97
524_N527_Q1.4040.97
414_W419_T1.4000.97
387_I417_R1.3800.96
103_A114_Q1.3690.96
554_S578_D1.3650.96
597_I638_L1.3650.96
296_N299_D1.3640.96
117_V120_Q1.3560.96
540_L563_V1.3550.96
141_N144_T1.3550.96
23_Q662_Y1.3550.96
28_K101_E1.3530.96
124_R206_C1.3520.96
126_Y131_L1.3480.96
343_L352_H1.3410.96
572_N578_D1.3380.96
597_I604_K1.3370.96
358_R388_H1.3350.96
515_Y545_L1.3330.96
93_G96_N1.3280.96
511_R515_Y1.3270.96
653_Y663_V1.3260.96
170_A211_F1.3260.96
228_T261_R1.3260.96
197_I202_I1.3230.96
643_I677_I1.3220.96
8_I654_I1.3200.95
554_S576_I1.3190.95
523_A526_Q1.3050.95
14_W18_N1.3050.95
363_D443_R1.3040.95
545_L613_W1.3020.95
418_L423_V1.3010.95
19_E83_R1.2980.95
347_Y644_L1.2850.95
453_A475_T1.2830.95
228_T263_V1.2780.95
34_E588_R1.2760.95
264_Y268_M1.2750.95
546_V568_S1.2730.94
504_M609_S1.2710.94
561_L582_A1.2620.94
97_E101_E1.2580.94
345_Y456_G1.2570.94
440_L453_A1.2550.94
583_I663_V1.2540.94
524_N531_S1.2500.94
330_R338_E1.2470.94
85_L288_I1.2470.94
348_H636_R1.2380.94
248_S416_K1.2300.93
377_A381_R1.2300.93
500_F505_V1.2240.93
522_I559_V1.2160.93
12_L83_R1.2150.93
264_Y287_S1.2130.93
44_N298_K1.2080.93
92_D292_G1.2070.93
560_N645_F1.2040.93
79_K82_S1.2010.93
477_D502_Y1.2010.93
95_Y109_L1.1910.92
597_I606_V1.1880.92
487_V500_F1.1860.92
171_L225_M1.1840.92
28_K97_E1.1830.92
487_V624_V1.1820.92
108_F195_P1.1800.92
119_Q186_P1.1800.92
157_L222_A1.1780.92
160_E271_A1.1760.92
207_L222_A1.1760.92
643_I676_A1.1760.92
596_Y609_S1.1740.92
534_T597_I1.1710.92
344_Y593_D1.1700.92
596_Y625_A1.1640.91
124_R208_D1.1610.91
553_S578_D1.1600.91
111_N201_N1.1560.91
553_S579_N1.1540.91
634_K638_L1.1520.91
35_R94_L1.1510.91
368_A442_S1.1510.91
595_V640_I1.1500.91
277_R284_R1.1490.91
642_D646_S1.1470.91
151_K173_E1.1470.91
321_H348_H1.1470.91
227_M262_F1.1450.91
521_E524_N1.1360.90
562_L641_I1.1330.90
479_R502_Y1.1310.90
131_L202_I1.1270.90
514_L625_A1.1250.90
384_D417_R1.1240.90
387_I390_A1.1190.90
13_S654_I1.1190.90
316_L589_Y1.1180.90
567_C582_A1.1170.90
531_S558_P1.1150.89
471_Y595_V1.1120.89
526_Q555_S1.1090.89
358_R385_S1.1060.89
367_L449_V1.1020.89
600_N605_K1.1020.89
532_G597_I1.1010.89
131_L179_V1.0950.89
599_E602_G1.0930.89
504_M517_M1.0920.88
9_E76_L1.0920.88
224_S265_Q1.0920.88
78_G285_Y1.0910.88
606_V634_K1.0880.88
477_D630_D1.0870.88
547_D576_I1.0850.88
223_Y269_P1.0820.88
577_S580_I1.0760.88
648_T670_K1.0730.88
131_L199_L1.0720.88
226_K263_V1.0650.87
479_R501_D1.0620.87
528_G531_S1.0590.87
559_V580_I1.0580.87
526_Q551_A1.0570.87
537_L596_Y1.0560.87
50_Y84_V1.0560.87
157_L204_R1.0520.87
323_W339_R1.0500.86
638_L642_D1.0490.86
535_L596_Y1.0490.86
482_N501_D1.0490.86
608_L628_L1.0470.86
631_P634_K1.0430.86
518_V549_L1.0410.86
204_R222_A1.0380.86
115_L197_I1.0380.86
223_Y268_M1.0370.86
308_K311_L1.0330.86
438_L624_V1.0250.85
54_F77_L1.0200.85
654_I660_N1.0180.85
244_M412_I1.0170.85
589_Y678_Y1.0170.85
365_S444_K1.0150.84
184_N187_P1.0140.84
676_A680_Y1.0130.84
355_E358_R1.0110.84
606_V637_V1.0110.84
455_I484_V1.0090.84
403_Q432_L1.0050.84
196_M306_V1.0010.84
510_S514_L0.9980.83
336_I341_V0.9980.83
514_L613_W0.9970.83
135_I172_L0.9970.83
520_R523_A0.9940.83
185_L195_P0.9930.83
172_L210_I0.9910.83
515_Y544_G0.9890.83
24_E652_R0.9880.83
111_N114_Q0.9870.83
6_L573_L0.9830.83
542_D619_D0.9780.82
38_F313_N0.9780.82
651_A663_V0.9770.82
600_N603_D0.9750.82
486_R501_D0.9750.82
343_L473_L0.9710.82
572_N575_G0.9700.82
440_L451_R0.9700.82
82_S86_K0.9690.82
74_R78_G0.9650.81
55_A257_A0.9630.81
601_G604_K0.9620.81
333_F443_R0.9590.81
665_R668_R0.9590.81
81_Q288_I0.9580.81
333_F452_Y0.9580.81
55_A230_D0.9550.81
514_L535_L0.9550.81
354_L385_S0.9550.81
75_H79_K0.9550.81
342_L471_Y0.9500.80
562_L583_I0.9500.80
525_A529_L0.9480.80
377_A436_A0.9390.80
418_L425_V0.9380.79
231_A242_S0.9370.79
304_P312_V0.9360.79
473_L477_D0.9360.79
541_V615_T0.9340.79
532_G581_R0.9290.79
319_L348_H0.9260.79
27_D662_Y0.9240.78
517_M607_Y0.9220.78
301_I467_L0.9200.78
397_T426_I0.9180.78
443_R452_Y0.9160.78
429_A622_I0.9160.78
337_R452_Y0.9150.78
515_Y522_I0.9120.78
471_Y593_D0.9100.77
454_H472_S0.9090.77
471_Y637_V0.9080.77
109_L198_L0.9070.77
630_D633_L0.9070.77
531_S555_S0.9060.77
110_I195_P0.9040.77
266_R289_V0.9040.77
445_E450_V0.9020.77
24_E30_N0.9000.77
351_E355_E0.8980.76
512_R544_G0.8980.76
549_L580_I0.8980.76
549_L559_V0.8980.76
525_A530_P0.8970.76
305_N312_V0.8970.76
628_L634_K0.8940.76
572_N656_K0.8920.76
522_I555_S0.8890.76
126_Y183_V0.8880.76
182_F299_D0.8880.76
505_V609_S0.8870.76
628_L633_L0.8870.76
32_L98_L0.8870.76
381_R462_E0.8860.75
371_I434_I0.8860.75
55_A235_L0.8860.75
543_K615_T0.8860.75
107_I308_K0.8850.75
13_S566_M0.8820.75
477_D480_I0.8810.75
337_R476_A0.8800.75
37_R305_N0.8780.75
93_G97_E0.8770.75
491_I622_I0.8760.75
633_L636_R0.8740.74
648_T668_R0.8710.74
562_L644_L0.8680.74
112_E201_N0.8680.74
120_Q205_Y0.8660.74
342_L637_V0.8640.74
72_H75_H0.8640.74
9_E69_S0.8630.74
108_F193_R0.8630.74
160_E221_N0.8620.73
112_E205_Y0.8600.73
635_Q638_L0.8590.73
653_Y661_R0.8580.73
80_I84_V0.8560.73
353_V474_L0.8560.73
115_L123_L0.8560.73
11_E57_L0.8540.73
572_N577_S0.8530.73
59_R234_D0.8520.73
510_S625_A0.8520.73
25_A94_L0.8510.72
59_R230_D0.8500.72
52_V615_T0.8500.72
136_T492_E0.8480.72
324_F332_G0.8470.72
197_I201_N0.8450.72
15_L84_V0.8450.72
544_G619_D0.8440.72
504_M510_S0.8420.72
332_G336_I0.8400.72
651_A673_A0.8400.72
534_T560_N0.8330.71
345_Y454_H0.8330.71
553_S572_N0.8320.71
524_N530_P0.8300.71
521_E599_E0.8290.70
559_V613_W0.8270.70
537_L563_V0.8270.70
157_L224_S0.8260.70
482_N486_R0.8260.70
126_Y130_Y0.8230.70
376_V462_E0.8170.69
198_L299_D0.8170.69
123_L206_C0.8160.69
90_E94_L0.8150.69
604_K634_K0.8150.69
554_S575_G0.8140.69
549_L613_W0.8130.69
399_V436_A0.8120.69
98_L300_F0.8120.69
530_P558_P0.8120.69
652_R662_Y0.8090.69
551_A554_S0.8080.69
453_A480_I0.8070.68
141_N145_D0.8070.68
321_H352_H0.8070.68
159_V207_L0.8040.68
19_E23_Q0.8010.68
527_Q530_P0.8000.68
37_R304_P0.7990.68
19_E87_A0.7970.67
94_L97_E0.7960.67
145_D148_Q0.7950.67
151_K171_L0.7940.67
648_T671_V0.7930.67
39_L98_L0.7920.67
509_N512_R0.7920.67
94_L98_L0.7900.67
51_K152_D0.7890.67
650_K672_R0.7870.66
534_T642_D0.7870.66
8_I571_P0.7860.66
524_N601_G0.7860.66
456_G471_Y0.7860.66
37_R467_L0.7850.66
37_R40_G0.7850.66
608_L637_V0.7830.66
169_Y275_V0.7820.66
102_M349_T0.7790.66
515_Y519_D0.7780.66
7_Y543_K0.7720.65
198_L201_N0.7720.65
301_I463_K0.7710.65
573_L578_D0.7710.65
438_L455_I0.7690.65
319_L678_Y0.7660.64
186_P197_I0.7650.64
451_R482_N0.7650.64
469_T593_D0.7640.64
648_T669_R0.7620.64
200_D294_Y0.7590.64
332_G359_Q0.7580.64
121_N124_R0.7570.63
88_D290_P0.7560.63
151_K156_Y0.7560.63
76_L242_S0.7550.63
340_D475_T0.7540.63
136_T370_K0.7530.63
455_I624_V0.7510.63
40_G402_L0.7510.63
297_F300_F0.7490.63
30_N313_N0.7490.63
553_S580_I0.7480.63
487_V505_V0.7480.63
345_Y353_V0.7460.62
480_I503_L0.7450.62
345_Y472_S0.7440.62
134_H442_S0.7440.62
388_H392_N0.7440.62
160_E272_L0.7430.62
334_D337_R0.7410.62
136_T489_N0.7400.62
123_L183_V0.7370.61
149_F230_D0.7370.61
307_G312_V0.7360.61
325_D329_F0.7350.61
264_Y273_V0.7350.61
571_P656_K0.7340.61
631_P635_Q0.7330.61
42_Y231_A0.7330.61
366_V394_K0.7300.61
373_I383_I0.7300.61
8_I570_I0.7290.61
95_Y297_F0.7250.60
218_D347_Y0.7210.60
367_L444_K0.7200.60
484_V624_V0.7190.59
31_P313_N0.7160.59
533_I559_V0.7150.59
198_L293_R0.7120.59
347_Y593_D0.7120.59
279_K589_Y0.7120.59
454_H460_F0.7100.59
141_N146_L0.7080.58
131_L183_V0.7070.58
259_P282_I0.7060.58
583_I645_F0.7040.58
636_R680_Y0.7040.58
643_I673_A0.7030.58
426_I492_E0.7020.58
586_V650_K0.7010.58
123_L646_S0.7010.58
290_P294_Y0.7010.58
89_Q93_G0.7010.58
344_Y379_D0.6990.57
358_R362_F0.6990.57
644_L677_I0.6990.57
581_R645_F0.6970.57
52_V55_A0.6970.57
266_R303_F0.6960.57
383_I418_L0.6960.57
500_F613_W0.6960.57
451_R485_R0.6950.57
667_N670_K0.6950.57
376_V410_A0.6950.57
308_K312_V0.6940.57
15_L80_I0.6940.57
354_L382_I0.6940.57
432_L506_S0.6930.57
524_N532_G0.6920.57
242_S568_S0.6920.57
122_W185_L0.6910.56
44_N467_L0.6900.56
51_K153_D0.6890.56
567_C575_G0.6890.56
161_I170_A0.6880.56
232_E461_N0.6870.56
89_Q104_R0.6840.56
22_L42_Y0.6830.56
650_K674_Q0.6830.56
134_H367_L0.6830.56
108_F114_Q0.6810.55
629_L637_V0.6810.55
18_N586_V0.6800.55
356_L452_Y0.6790.55
451_R481_T0.6790.55
641_I645_F0.6780.55
649_V670_K0.6770.55
114_Q117_V0.6770.55
36_M107_I0.6760.55
127_F632_R0.6750.55
140_I169_Y0.6740.55
664_P667_N0.6720.54
331_N337_R0.6720.54
382_I566_M0.6720.54
274_E284_R0.6700.54
82_S103_A0.6700.54
112_E197_I0.6700.54
24_E586_V0.6690.54
664_P668_R0.6690.54
353_V439_F0.6680.54
648_T664_P0.6670.54
553_S573_L0.6670.54
139_L170_A0.6660.54
72_H76_L0.6660.54
553_S571_P0.6650.54
112_E204_R0.6630.53
17_F21_V0.6630.53
530_P601_G0.6630.53
529_L599_E0.6630.53
639_D642_D0.6630.53
83_R87_A0.6630.53
451_R493_N0.6620.53
341_V474_L0.6620.53
178_K395_K0.6590.53
353_V454_H0.6590.53
84_V87_A0.6590.53
399_V428_S0.6590.53
361_S385_S0.6580.53
533_I549_L0.6550.52
257_A539_N0.6550.52
235_L246_L0.6550.52
545_L619_D0.6550.52
16_S660_N0.6540.52
656_K659_S0.6530.52
274_E278_E0.6530.52
505_V624_V0.6520.52
33_I312_V0.6520.52
170_A494_P0.6510.52
353_V382_I0.6500.52
521_E604_K0.6490.52
161_I219_A0.6490.52
182_F303_F0.6490.52
332_G355_E0.6480.52
442_S493_N0.6480.52
116_S668_R0.6460.52
57_L80_I0.6430.51
52_V257_A0.6420.51
539_N566_M0.6420.51
464_T539_N0.6420.51
324_F343_L0.6410.51
581_R663_V0.6390.51
432_L490_F0.6390.51
207_L432_L0.6350.50
95_Y198_L0.6340.50
148_Q419_T0.6330.50
96_N664_P0.6330.50
144_T587_D0.6320.50
119_Q185_L0.6310.50
571_P577_S0.6300.50
41_I45_N0.6290.50
539_N565_G0.6290.50
51_K414_W0.6290.50
395_K424_H0.6280.50
12_L79_K0.6280.50
504_M625_A0.6270.49
118_N121_N0.6270.49
648_T651_A0.6250.49
268_M273_V0.6240.49
613_W618_I0.6240.49
232_E391_H0.6240.49
639_D643_I0.6230.49
339_R476_A0.6230.49
550_Y580_I0.6220.49
428_S507_P0.6220.49
400_V414_W0.6210.49
50_Y81_Q0.6210.49
238_E382_I0.6210.49
635_Q639_D0.6210.49
343_L503_L0.6210.49
339_R448_E0.6200.49
29_S670_K0.6200.49
543_K547_D0.6180.48
135_I210_I0.6170.48
252_K409_E0.6140.48
127_F628_L0.6140.48
518_V521_E0.6130.48
252_K391_H0.6120.48
124_R128_K0.6120.48
436_A624_V0.6120.48
412_I432_L0.6120.48
483_E502_Y0.6110.48
219_A423_V0.6110.48
184_N628_L0.6100.48
34_E589_Y0.6100.48
284_R607_Y0.6090.47
571_P578_D0.6090.47
583_I653_Y0.6080.47
473_L633_L0.6070.47
251_L409_E0.6060.47
480_I527_Q0.6060.47
166_T365_S0.6050.47
233_Y250_S0.6040.47
615_T618_I0.6040.47
182_F198_L0.6040.47
173_E256_T0.6040.47
207_L219_A0.6030.47
242_S403_Q0.6020.47
293_R299_D0.6020.47
440_L485_R0.6000.46
9_E72_H0.6000.46
161_I211_F0.6000.46
30_N650_K0.5990.46
399_V461_N0.5980.46
127_F418_L0.5970.46
96_N100_L0.5960.46
632_R636_R0.5960.46
376_V383_I0.5960.46
139_L494_P0.5960.46
30_N652_R0.5950.46
201_N527_Q0.5950.46
150_L271_A0.5950.46
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37_R562_L0.5940.46
51_K200_D0.5940.46
88_D91_F0.5930.46
117_V655_D0.5920.46
343_L353_V0.5920.46
451_R489_N0.5920.46
316_L319_L0.5920.46
314_K347_Y0.5920.46
299_D580_I0.5910.45
52_V232_E0.5910.45
525_A559_V0.5900.45
86_K90_E0.5900.45
233_Y251_L0.5900.45
150_L168_R0.5900.45
110_I185_L0.5900.45
127_F179_V0.5890.45
7_Y550_Y0.5890.45
211_F409_E0.5880.45
442_S453_A0.5880.45
438_L481_T0.5870.45
507_P584_S0.5870.45
500_F609_S0.5870.45
333_F336_I0.5870.45
184_N196_M0.5860.45
15_L467_L0.5860.45
24_E392_N0.5860.45
335_A338_E0.5860.45
480_I629_L0.5860.45
473_L520_R0.5850.45
540_L561_L0.5850.45
167_I220_L0.5850.45
76_L80_I0.5850.45
93_G603_D0.5840.45
88_D92_D0.5840.45
666_G670_K0.5840.45
37_R84_V0.5840.45
179_V199_L0.5840.45
93_G117_V0.5840.45
607_Y625_A0.5830.45
197_I205_Y0.5820.44
362_F385_S0.5820.44
26_A97_E0.5820.44
347_Y465_A0.5820.44
460_F660_N0.5800.44
12_L546_V0.5800.44
116_S188_E0.5790.44
106_Q193_R0.5790.44
235_L257_A0.5780.44
491_I601_G0.5780.44
23_Q26_A0.5770.44
380_S400_V0.5770.44
524_N604_K0.5770.44
649_V672_R0.5770.44
301_I304_P0.5770.44
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40_G461_N0.5750.44
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257_A372_N0.5740.44
33_I311_L0.5740.44
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66_E75_H0.5710.43
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568_S615_T0.5690.43
354_L436_A0.5690.43
263_V293_R0.5680.43
37_R231_A0.5680.43
43_S88_D0.5680.43
269_P348_H0.5680.43
387_I425_V0.5670.43
471_Y608_L0.5670.43
480_I624_V0.5670.43
77_L81_Q0.5660.43
60_R240_E0.5660.43
487_V503_L0.5660.43
484_V487_V0.5650.43
98_L649_V0.5650.43
50_Y622_I0.5650.43
187_P193_R0.5640.42
549_L577_S0.5630.42
425_V584_S0.5630.42
78_G628_L0.5630.42
31_P588_R0.5620.42
244_M415_A0.5620.42
232_E242_S0.5610.42
370_K397_T0.5610.42
117_V121_N0.5590.42
122_W126_Y0.5590.42
69_S353_V0.5590.42
230_D255_L0.5580.42
98_L656_K0.5580.42
673_A677_I0.5580.42
325_D654_I0.5570.42
290_P438_L0.5570.42
238_E251_L0.5560.42
670_K676_A0.5560.42
14_W539_N0.5560.42
399_V403_Q0.5550.42
92_D291_G0.5540.41
228_T260_V0.5540.41
119_Q122_W0.5540.41
92_D297_F0.5540.41
236_V423_V0.5530.41
95_Y300_F0.5530.41
182_F511_R0.5530.41
268_M272_L0.5530.41
184_N306_V0.5520.41
51_K156_Y0.5520.41
15_L36_M0.5520.41
138_I158_A0.5520.41
39_L202_I0.5510.41
649_V652_R0.5510.41
586_V674_Q0.5500.41
275_V279_K0.5500.41
478_A499_T0.5490.41
69_S423_V0.5490.41
450_V476_A0.5480.41
31_P34_E0.5480.41
391_H421_A0.5470.41
546_V580_I0.5470.41
332_G481_T0.5460.41
482_N531_S0.5460.41
23_Q30_N0.5460.41
61_I77_L0.5460.41
92_D290_P0.5450.40
270_N656_K0.5450.40
154_Y483_E0.5450.40
7_Y577_S0.5440.40
336_I452_Y0.5440.40
139_L398_V0.5430.40
29_S649_V0.5420.40
385_S398_V0.5420.40
116_S479_R0.5420.40
150_L173_E0.5420.40
181_R199_L0.5420.40
322_I601_G0.5410.40
677_I680_Y0.5410.40
373_I625_A0.5400.40
112_E123_L0.5400.40
156_Y173_E0.5400.40
337_R443_R0.5390.40
469_T644_L0.5390.40
10_K539_N0.5390.40
338_E448_E0.5390.40
329_F595_V0.5380.40
323_W341_V0.5380.40
150_L430_P0.5370.40
535_L545_L0.5370.40
232_E236_V0.5370.40
344_Y472_S0.5360.39
438_L526_Q0.5360.39
138_I361_S0.5360.39
322_I348_H0.5360.39
539_N618_I0.5350.39
117_V664_P0.5350.39
503_L624_V0.5350.39
102_M627_P0.5350.39
140_I253_Q0.5350.39
646_S676_A0.5340.39
231_A402_L0.5340.39
522_I557_V0.5330.39
403_Q414_W0.5330.39
333_F441_I0.5330.39
574_E668_R0.5330.39
546_V569_L0.5330.39
649_V673_A0.5330.39
151_K154_Y0.5320.39
236_V622_I0.5320.39
78_G82_S0.5310.39
269_P624_V0.5300.39
93_G666_G0.5300.39
27_D652_R0.5290.39
518_V545_L0.5290.39
11_E541_V0.5290.39
77_L80_I0.5280.39
218_D667_N0.5280.39
248_S376_V0.5280.39
111_N628_L0.5270.39
339_R668_R0.5260.38
558_P651_A0.5260.38
82_S189_A0.5260.38
537_L561_L0.5260.38
473_L628_L0.5250.38
441_I474_L0.5250.38
154_Y173_E0.5250.38
161_I415_A0.5250.38
152_D469_T0.5240.38
303_F388_H0.5240.38
461_N464_T0.5240.38
335_A339_R0.5240.38
504_M624_V0.5230.38
522_I553_S0.5230.38
665_R670_K0.5230.38
595_V620_Y0.5230.38
11_E76_L0.5230.38
316_L588_R0.5220.38
267_D289_V0.5220.38
14_W17_F0.5220.38
157_L432_L0.5220.38
481_T484_V0.5220.38
268_M487_V0.5210.38
383_I400_V0.5210.38
174_I207_L0.5210.38
294_Y299_D0.5210.38
333_F359_Q0.5210.38
361_S521_E0.5200.38
143_D243_L0.5200.38
136_T414_W0.5200.38
365_S448_E0.5200.38
533_I605_K0.5200.38
354_L381_R0.5200.38
9_E56_E0.5190.38
131_L313_N0.5190.38
397_T609_S0.5190.38
263_V434_I0.5180.38
206_C209_D0.5180.38
58_K545_L0.5180.38
132_R493_N0.5170.37
135_I432_L0.5170.37
273_V277_R0.5170.37
455_I609_S0.5170.37
139_L225_M0.5170.37
311_L325_D0.5170.37
230_D250_S0.5160.37
388_H391_H0.5160.37
243_L257_A0.5160.37
301_I305_N0.5150.37
161_I288_I0.5150.37
571_P576_I0.5150.37
479_R630_D0.5150.37
50_Y88_D0.5140.37
541_V566_M0.5130.37
250_S376_V0.5130.37
97_E278_E0.5130.37
243_L353_V0.5120.37
403_Q410_A0.5120.37
274_E277_R0.5120.37
353_V452_Y0.5120.37
160_E303_F0.5120.37
534_T638_L0.5110.37
395_K403_Q0.5110.37
438_L625_A0.5110.37
259_P652_R0.5110.37
50_Y156_Y0.5110.37
527_Q601_G0.5100.37
34_E313_N0.5090.37
57_L554_S0.5090.37
107_I297_F0.5080.37
533_I598_F0.5070.36
400_V403_Q0.5070.36
259_P279_K0.5070.36
555_S563_V0.5060.36
182_F306_V0.5060.36
355_E376_V0.5050.36
36_M78_G0.5040.36
563_V666_G0.5040.36
52_V231_A0.5040.36
244_M577_S0.5040.36
81_Q286_D0.5040.36
14_W40_G0.5040.36
359_Q545_L0.5030.36
7_Y604_K0.5030.36
121_N635_Q0.5020.36
302_N571_P0.5020.36
365_S445_E0.5020.36
640_I644_L0.5020.36
233_Y263_V0.5020.36
585_I644_L0.5010.36
640_I677_I0.5010.36
73_S385_S0.5010.36
122_W183_V0.5010.36
116_S655_D0.5000.36
539_N596_Y0.5000.36
263_V288_I0.5000.36
276_L349_T0.5000.36
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2o8rA 2 0.939 100 0.258 Contact Map
1xdpA 4 0.9985 100 0.26 Contact Map
1v0wA 1 0.5102 100 0.907 Contact Map
3hsiA 2 0.4971 99.8 0.931 Contact Map
4gelA 2 0.2703 99.4 0.949 Contact Map
1byrA 2 0.2151 99.2 0.955 Contact Map
4ggjA 2 0.2398 99.1 0.956 Contact Map
4urjA 1 0.2326 98.2 0.967 Contact Map
4rctA 2 0.2616 91.4 0.981 Contact Map
2c1lA 2 0.2674 90.1 0.982 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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