NAGB - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

NAGB - Glucosamine-6-phosphate deaminase

UniProt:	P0A759	Sequences: MRLIPLTTAEQVGKWAARHIVNRINAFKPTADRPFVLGLPTGGTPMTTYKALVEMHKAGQVSFKHVVTFNMDEYVGLPKEHPESYYSFMHRNFFDHVDIPAENINLLNGNAPDIDAECRQYEEKIRSYGKIHLFMGGVGNDGHIAFNEPASSLASRTRIKTLTHDTRVANSRFFDNDVNQVPKYALTVGVGTLLDAEEVMILVLGSQKALALQAAVEGCVNHMWTISCLQLHPKAIMVCDEPSTMELKVKTLRYFNELEAENIKGL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10633
Length:	266 (228)
Sequences:	5181 (3772)
Seq/√Len:	249.8

ECOLI - NAGB YIEK AGAI
BACSU - GAMA NAGB

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
87_S	91_R	3.503	1.00
210_L	246_E	2.907	1.00
206_S	242_P	2.756	1.00
7_T	241_E	2.704	1.00
198_E	234_K	2.660	1.00
117_E	120_Q	2.563	1.00
140_N	207_Q	2.512	1.00
51_A	54_E	2.499	1.00
8_T	11_Q	2.433	1.00
212_L	239_C	2.398	1.00
90_H	95_D	2.244	1.00
23_R	198_E	2.243	1.00
123_E	127_S	2.225	1.00
107_L	186_L	2.167	1.00
62_S	98_D	2.105	1.00
210_L	214_A	2.096	1.00
6_L	15_W	2.089	1.00
13_G	47_T	2.078	1.00
239_C	244_T	2.037	1.00
23_R	35_F	2.004	1.00
20_I	48_T	1.973	1.00
79_K	86_Y	1.966	1.00
177_D	180_Q	1.938	1.00
91_R	95_D	1.912	1.00
14_K	51_A	1.911	1.00
67_V	105_N	1.905	1.00
12_V	204_L	1.894	1.00
134_F	196_A	1.888	1.00
105_N	124_K	1.882	1.00
132_H	197_E	1.842	1.00
68_T	94_F	1.836	1.00
22_N	26_A	1.806	1.00
86_Y	90_H	1.769	1.00
29_P	33_R	1.712	1.00
46_M	92_N	1.709	1.00
214_A	224_W	1.708	1.00
194_L	228_C	1.686	1.00
34_P	67_V	1.666	1.00
9_A	13_G	1.665	1.00
164_H	168_V	1.655	1.00
113_D	116_A	1.627	1.00
213_Q	217_E	1.603	1.00
53_V	96_H	1.592	1.00
67_V	103_N	1.581	1.00
44_T	202_L	1.578	1.00
119_R	123_E	1.571	1.00
21_V	61_V	1.569	1.00
19_H	238_V	1.563	1.00
86_Y	106_L	1.563	1.00
20_I	37_L	1.521	1.00
90_H	101_A	1.520	1.00
116_A	120_Q	1.497	1.00
138_V	203_V	1.495	1.00
206_S	245_M	1.467	1.00
48_T	135_M	1.451	1.00
50_K	92_N	1.447	1.00
203_V	212_L	1.447	1.00
24_I	35_F	1.443	1.00
64_K	98_D	1.422	1.00
5_P	244_T	1.417	1.00
24_I	66_V	1.395	1.00
140_N	169_A	1.385	1.00
120_Q	124_K	1.383	1.00
32_D	197_E	1.349	1.00
54_E	58_A	1.346	1.00
211_A	224_W	1.329	1.00
20_I	133_L	1.329	1.00
7_T	11_Q	1.315	1.00
111_A	117_E	1.301	1.00
138_V	215_A	1.300	1.00
38_G	134_F	1.292	1.00
6_L	238_V	1.292	1.00
133_L	200_M	1.291	1.00
142_G	224_W	1.287	1.00
40_P	71_M	1.286	1.00
16_A	48_T	1.282	1.00
188_V	192_T	1.252	1.00
16_A	200_M	1.237	1.00
80_E	87_S	1.233	1.00
165_D	169_A	1.225	1.00
215_A	226_I	1.223	1.00
123_E	126_R	1.210	1.00
75_V	114_I	1.209	1.00
82_P	87_S	1.209	1.00
215_A	237_M	1.207	1.00
69_F	128_Y	1.204	1.00
38_G	71_M	1.201	1.00
122_E	192_T	1.200	1.00
120_Q	123_E	1.184	1.00
111_A	114_I	1.170	1.00
19_H	200_M	1.159	1.00
84_S	87_S	1.158	1.00
145_A	193_L	1.152	1.00
48_T	202_L	1.150	1.00
10_E	47_T	1.150	1.00
198_E	236_I	1.149	1.00
36_V	67_V	1.144	1.00
70_N	89_M	1.144	1.00
36_V	69_F	1.143	1.00
47_T	50_K	1.140	1.00
175_D	180_Q	1.134	1.00
126_R	195_D	1.133	1.00
138_V	226_I	1.133	1.00
21_V	25_N	1.123	1.00
6_L	12_V	1.120	1.00
99_I	103_N	1.116	1.00
124_K	127_S	1.110	1.00
100_P	103_N	1.104	1.00
15_W	18_R	1.098	1.00
9_A	47_T	1.091	1.00
6_L	11_Q	1.081	1.00
209_A	245_M	1.080	1.00
175_D	178_V	1.063	1.00
18_R	22_N	1.047	1.00
115_D	119_R	1.021	1.00
231_L	235_A	1.021	1.00
19_H	198_E	1.017	1.00
16_A	202_L	1.017	1.00
78_P	110_N	1.013	1.00
4_I	236_I	1.009	1.00
46_M	50_K	1.006	1.00
63_F	66_V	1.005	1.00
9_A	204_L	0.997	1.00
209_A	213_Q	0.993	1.00
38_G	131_I	0.993	1.00
88_F	92_N	0.991	1.00
118_C	122_E	0.987	1.00
211_A	214_A	0.987	1.00
12_V	238_V	0.980	1.00
62_S	65_H	0.979	1.00
50_K	96_H	0.978	1.00
178_V	181_V	0.976	1.00
11_Q	14_K	0.975	1.00
90_H	104_I	0.974	1.00
25_N	60_Q	0.970	1.00
191_G	195_D	0.968	1.00
35_F	66_V	0.960	1.00
46_M	88_F	0.957	1.00
94_F	104_I	0.951	1.00
16_A	238_V	0.940	1.00
153_L	228_C	0.939	1.00
108_N	117_E	0.932	1.00
5_P	241_E	0.930	1.00
116_A	119_R	0.930	1.00
35_F	133_L	0.924	1.00
10_E	51_A	0.917	1.00
4_I	15_W	0.913	1.00
178_V	183_K	0.901	1.00
26_A	31_A	0.896	1.00
4_I	238_V	0.896	1.00
63_F	97_V	0.894	1.00
23_R	26_A	0.888	1.00
125_I	131_I	0.885	1.00
190_V	228_C	0.877	1.00
209_A	246_E	0.876	1.00
40_P	134_F	0.875	1.00
19_H	23_R	0.872	1.00
90_H	106_L	0.871	1.00
213_Q	246_E	0.869	0.99
39_L	68_T	0.868	0.99
20_I	135_M	0.865	0.99
29_P	32_D	0.860	0.99
114_I	186_L	0.858	0.99
212_L	215_A	0.857	0.99
138_V	212_L	0.857	0.99
13_G	48_T	0.854	0.99
100_P	104_I	0.847	0.99
206_S	246_E	0.844	0.99
194_L	232_H	0.843	0.99
9_A	12_V	0.840	0.99
215_A	224_W	0.838	0.99
61_V	66_V	0.837	0.99
214_A	223_M	0.828	0.99
78_P	81_H	0.826	0.99
224_W	227_S	0.825	0.99
32_D	132_H	0.821	0.99
196_A	199_V	0.819	0.99
199_V	235_A	0.817	0.99
72_D	143_H	0.817	0.99
39_L	49_Y	0.816	0.99
131_I	134_F	0.815	0.99
43_G	88_F	0.809	0.99
69_F	124_K	0.808	0.99
201_I	226_I	0.797	0.99
67_V	100_P	0.794	0.99
64_K	100_P	0.784	0.99
29_P	65_H	0.782	0.99
212_L	237_M	0.779	0.99
89_M	94_F	0.778	0.99
130_K	197_E	0.777	0.99
179_N	183_K	0.775	0.99
45_P	49_Y	0.771	0.99
220_V	231_L	0.761	0.99
47_T	51_A	0.760	0.99
44_T	204_L	0.760	0.99
67_V	128_Y	0.753	0.99
153_L	222_H	0.748	0.98
101_A	104_I	0.745	0.98
79_K	106_L	0.743	0.98
18_R	60_Q	0.743	0.98
79_K	90_H	0.742	0.98
50_K	54_E	0.741	0.98
69_F	105_N	0.740	0.98
10_E	50_K	0.738	0.98
33_R	65_H	0.738	0.98
122_E	126_R	0.736	0.98
85_Y	185_A	0.735	0.98
219_C	227_S	0.734	0.98
71_M	193_L	0.733	0.98
71_M	188_V	0.732	0.98
125_I	130_K	0.730	0.98
164_H	167_R	0.729	0.98
194_L	231_L	0.726	0.98
10_E	14_K	0.725	0.98
214_A	218_G	0.719	0.98
239_C	243_S	0.718	0.98
114_I	184_Y	0.717	0.98
142_G	211_A	0.717	0.98
14_K	18_R	0.715	0.98
193_L	199_V	0.713	0.98
17_A	52_L	0.708	0.98
86_Y	104_I	0.707	0.98
140_N	211_A	0.707	0.98
117_E	186_L	0.705	0.98
43_G	46_M	0.701	0.98
240_D	243_S	0.688	0.97
144_I	201_I	0.687	0.97
40_P	144_I	0.687	0.97
41_T	85_Y	0.683	0.97
122_E	167_R	0.682	0.97
136_G	193_L	0.678	0.97
135_M	202_L	0.675	0.97
194_L	229_L	0.674	0.97
83_E	183_K	0.672	0.97
99_I	104_I	0.672	0.97
24_I	37_L	0.668	0.97
70_N	106_L	0.660	0.97
209_A	244_T	0.656	0.97
37_L	68_T	0.656	0.97
25_N	61_V	0.650	0.96
5_P	239_C	0.648	0.96
216_V	237_M	0.646	0.96
109_G	117_E	0.644	0.96
162_L	170_N	0.643	0.96
76_G	114_I	0.643	0.96
17_A	51_A	0.638	0.96
79_K	110_N	0.636	0.96
21_V	52_L	0.636	0.96
19_H	236_I	0.635	0.96
215_A	230_Q	0.635	0.96
166_T	169_A	0.634	0.96
108_N	120_Q	0.628	0.96
69_F	125_I	0.625	0.95
29_P	35_F	0.623	0.95
11_Q	15_W	0.623	0.95
163_T	167_R	0.621	0.95
29_P	62_S	0.619	0.95
19_H	22_N	0.617	0.95
76_G	109_G	0.615	0.95
107_L	121_Y	0.614	0.95
77_L	87_S	0.614	0.95
68_T	89_M	0.611	0.95
210_L	213_Q	0.611	0.95
53_V	92_N	0.608	0.95
77_L	81_H	0.607	0.95
99_I	102_E	0.603	0.95
77_L	84_S	0.602	0.94
15_W	238_V	0.602	0.94
3_L	216_V	0.602	0.94
146_F	185_A	0.600	0.94
39_L	89_M	0.599	0.94
21_V	59_G	0.597	0.94
108_N	111_A	0.596	0.94
83_E	180_Q	0.594	0.94
134_F	193_L	0.593	0.94
190_V	225_T	0.592	0.94
150_A	222_H	0.592	0.94
199_V	231_L	0.591	0.94
138_V	211_A	0.591	0.94
70_N	86_Y	0.589	0.94
15_W	19_H	0.588	0.94
137_G	208_K	0.587	0.94
201_I	237_M	0.586	0.94
148_E	185_A	0.585	0.94
52_L	63_F	0.583	0.93
145_A	187_T	0.578	0.93
93_F	97_V	0.576	0.93
43_G	140_N	0.568	0.93
151_S	223_M	0.568	0.93
69_F	131_I	0.565	0.92
85_Y	148_E	0.562	0.92
228_C	231_L	0.558	0.92
168_V	178_V	0.556	0.92
107_L	117_E	0.555	0.92
20_I	52_L	0.555	0.92
113_D	184_Y	0.554	0.92
212_L	216_V	0.553	0.92
72_D	208_K	0.552	0.92
118_C	186_L	0.550	0.91
25_N	59_G	0.550	0.91
192_T	195_D	0.550	0.91
199_V	229_L	0.548	0.91
187_T	191_G	0.548	0.91
59_G	63_F	0.547	0.91
200_M	238_V	0.545	0.91
40_P	49_Y	0.543	0.91
25_N	30_T	0.543	0.91
71_M	145_A	0.542	0.91
23_R	133_L	0.541	0.91
211_A	215_A	0.539	0.91
17_A	21_V	0.539	0.91
85_Y	146_F	0.538	0.90
118_C	187_T	0.538	0.90
41_T	148_E	0.536	0.90
153_L	170_N	0.531	0.90
125_I	129_G	0.531	0.90
89_M	104_I	0.530	0.90
190_V	229_L	0.529	0.90
20_I	200_M	0.529	0.90
21_V	60_Q	0.529	0.90
111_A	116_A	0.528	0.90
177_D	183_K	0.528	0.90
18_R	59_G	0.523	0.89
13_G	17_A	0.520	0.89
16_A	135_M	0.519	0.89
72_D	137_G	0.518	0.89
125_I	192_T	0.515	0.88
167_R	187_T	0.515	0.88
170_N	174_F	0.513	0.88
13_G	51_A	0.511	0.88
84_S	109_G	0.509	0.88
3_L	239_C	0.509	0.88
242_P	245_M	0.509	0.88
221_N	227_S	0.507	0.88
77_L	80_E	0.506	0.88
180_Q	183_K	0.503	0.87
130_K	192_T	0.503	0.87
124_K	128_Y	0.503	0.87
71_M	134_F	0.502	0.87
167_R	183_K	0.502	0.87
106_L	110_N	0.500	0.87
166_T	170_N	0.500	0.87

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3icoA	1	0.8797	100	0.138	Contact Map
3tx2A	1	0.8759	100	0.142	Contact Map
4tm7A	1	0.8722	100	0.145	Contact Map
3eb9A	1	0.8722	100	0.165	Contact Map
3e15A	2	0.9248	100	0.202	Contact Map
3cssA	1	0.8759	100	0.213	Contact Map
1ne7A	4	0.9962	100	0.214	Contact Map
3lwdA	2	0.8346	100	0.215	Contact Map
1fs5A	4	0.9925	100	0.216	Contact Map
1vl1A	1	0.812	100	0.219	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0111 seconds.