GREMLIN Database
YCEF - Maf-like protein YceF
UniProt: P0A729 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11438
Length: 194 (181)
Sequences: 5651 (4098)
Seq/√Len: 304.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
93_R132_E3.0631.00
85_E140_R2.9231.00
99_I126_H2.7991.00
77_E94_K2.7641.00
89_R136_D2.7581.00
75_D98_N2.5541.00
14_R18_E2.4191.00
87_N90_L2.3171.00
101_T124_D2.2961.00
101_T122_P2.2851.00
124_D165_E2.1901.00
46_L120_V2.1341.00
49_A107_A2.1291.00
31_V51_E2.0571.00
126_H163_R2.0231.00
126_H162_E2.0171.00
3_K25_E1.9821.00
89_R139_V1.9531.00
99_I124_D1.8881.00
123_F172_L1.8801.00
50_Q54_Q1.8631.00
83_L87_N1.7861.00
117_Q186_R1.7291.00
131_S134_E1.7291.00
96_S130_L1.6361.00
139_V145_L1.6321.00
121_E171_T1.6311.00
85_E139_V1.6221.00
14_R24_F1.6081.00
107_A118_T1.6031.00
103_Y122_P1.5841.00
123_F171_T1.5671.00
130_L135_I1.5661.00
121_E179_A1.5471.00
54_Q116_L1.5431.00
74_L98_N1.5351.00
157_G160_L1.5231.00
89_R93_R1.4841.00
53_A67_G1.4831.00
175_L180_L1.4761.00
9_T28_A1.4761.00
117_Q183_M1.4681.00
119_E179_A1.4511.00
27_A59_R1.4471.00
39_E47_R1.4441.00
85_E145_L1.4351.00
50_Q118_T1.4321.00
85_E89_R1.4281.00
89_R135_I1.4261.00
143_H155_G1.3951.00
4_L66_I1.3921.00
15_A19_K1.3871.00
119_E183_M1.3771.00
18_E24_F1.3601.00
91_Q150_S1.3501.00
29_P56_L1.3401.00
169_P173_V1.3191.00
128_R178_I1.2941.00
103_Y120_V1.2901.00
50_Q116_L1.2891.00
106_L119_E1.2791.00
159_T181_C1.2641.00
73_V103_Y1.2561.00
40_S43_Q1.2401.00
53_A109_F1.2401.00
128_R182_Q1.2351.00
132_E136_D1.2331.00
46_L118_T1.2261.00
96_S132_E1.2241.00
27_A60_Y1.2021.00
85_E136_D1.2011.00
44_L71_V1.1991.00
96_S129_H1.1991.00
100_V151_F1.1941.00
90_L94_K1.1681.00
128_R134_E1.1621.00
7_A67_G1.1591.00
74_L94_K1.1531.00
47_R51_E1.1491.00
106_L180_L1.1281.00
88_A150_S1.1141.00
79_T91_Q1.1141.00
108_L183_M1.1101.00
139_V144_P1.0971.00
128_R162_E1.0961.00
84_T87_N1.0931.00
12_W146_H1.0881.00
14_R26_C1.0841.00
55_S59_R1.0831.00
66_I180_L1.0781.00
134_E185_R1.0671.00
89_R132_E1.0591.00
147_C152_K1.0541.00
50_Q107_A1.0341.00
133_A137_N1.0321.00
123_F164_L1.0291.00
3_K63_H1.0201.00
9_T29_P1.0131.00
19_K158_I1.0101.00
88_A144_P1.0051.00
15_A18_E1.0021.00
66_I108_L0.9981.00
117_Q187_E0.9971.00
153_S173_V0.9811.00
44_L78_I0.9771.00
136_D140_R0.9741.00
110_N187_E0.9681.00
30_E55_S0.9651.00
35_P44_L0.9641.00
109_F116_L0.9531.00
44_L48_L0.9511.00
36_R51_E0.9491.00
71_V78_I0.9311.00
73_V76_G0.9291.00
142_E145_L0.9261.00
127_F157_G0.9251.00
93_R135_I0.9241.00
5_I63_H0.9141.00
68_S104_T0.9031.00
36_R39_E0.9021.00
164_L172_L0.9021.00
45_V105_G0.9011.00
179_A183_M0.8981.00
79_T94_K0.8941.00
87_N91_Q0.8931.00
31_V55_S0.8871.00
27_A56_L0.8811.00
31_V48_L0.8761.00
141_K156_F0.8641.00
5_I27_A0.8601.00
126_H165_E0.8591.00
92_L150_S0.8591.00
51_E54_Q0.8491.00
57_A109_F0.8471.00
5_I56_L0.8431.00
181_C185_R0.8361.00
45_V103_Y0.8321.00
36_R47_R0.8291.00
88_A139_V0.8271.00
18_E23_S0.8251.00
42_R46_L0.8211.00
56_L65_I0.8191.00
77_E90_L0.8081.00
106_L176_P0.7961.00
95_A151_F0.7941.00
64_L108_L0.7931.00
137_N140_R0.7891.00
73_V101_T0.7860.99
95_A100_V0.7840.99
20_L181_C0.7800.99
107_A116_L0.7770.99
46_L50_Q0.7690.99
170_N177_L0.7650.99
12_W154_E0.7630.99
43_Q46_L0.7620.99
66_I175_L0.7600.99
143_H156_F0.7590.99
115_H187_E0.7540.99
16_L177_L0.7530.99
54_Q109_F0.7450.99
106_L183_M0.7440.99
41_P78_I0.7430.99
105_G120_V0.7420.99
16_L175_L0.7390.99
62_D111_S0.7310.99
108_L180_L0.7290.99
86_E90_L0.7290.99
130_L160_L0.7270.99
67_G109_F0.7230.99
29_P55_S0.7160.99
183_M186_R0.7140.99
21_Q141_K0.7090.99
35_P78_I0.7070.99
75_D94_K0.7060.99
17_L24_F0.7040.99
105_G171_T0.7000.99
119_E182_Q0.6940.99
53_A107_A0.6920.99
73_V78_I0.6890.99
119_E186_R0.6880.99
70_Q102_F0.6850.99
44_L47_R0.6810.99
72_C102_F0.6810.99
42_R122_P0.6800.99
56_L67_G0.6790.99
27_A63_H0.6740.98
74_L79_T0.6740.98
97_G129_H0.6740.98
5_I60_Y0.6700.98
80_G148_A0.6690.98
34_T37_S0.6690.98
12_W15_A0.6680.98
170_N173_V0.6580.98
45_V71_V0.6520.98
42_R120_V0.6500.98
74_L95_A0.6500.98
72_C79_T0.6500.98
147_C154_E0.6460.98
62_D112_A0.6420.98
48_L51_E0.6410.98
180_L183_M0.6380.98
135_I139_V0.6370.98
12_W147_C0.6370.98
65_I109_F0.6350.98
4_L22_I0.6340.98
48_L67_G0.6280.98
108_L187_E0.6240.97
142_E155_G0.6240.97
162_E182_Q0.6230.97
41_P45_V0.6220.97
16_L173_V0.6170.97
85_E142_E0.6160.97
17_L66_I0.6110.97
16_L170_N0.6110.97
16_L19_K0.6080.97
96_S135_I0.6060.97
84_T90_L0.5950.97
151_F161_F0.5910.96
80_G91_Q0.5890.96
136_D139_V0.5880.96
164_L169_P0.5870.96
88_A92_L0.5850.96
37_S80_G0.5840.96
123_F166_G0.5840.96
68_S171_T0.5800.96
61_P111_S0.5790.96
170_N178_I0.5770.96
47_R50_Q0.5760.96
40_S44_L0.5750.96
57_A65_I0.5720.96
20_L177_L0.5700.96
54_Q58_S0.5700.96
22_I181_C0.5680.96
137_N141_K0.5670.96
67_G107_A0.5650.95
133_A136_D0.5650.95
26_C56_L0.5640.95
64_L110_N0.5630.95
9_T31_V0.5600.95
60_Y63_H0.5600.95
35_P39_E0.5580.95
9_T30_E0.5550.95
112_A115_H0.5550.95
110_N115_H0.5550.95
51_E55_S0.5530.95
183_M187_E0.5530.95
158_I177_L0.5480.95
71_V80_G0.5470.95
156_F159_T0.5460.95
25_E63_H0.5430.94
153_S169_P0.5410.94
104_T176_P0.5390.94
86_E89_R0.5390.94
64_L111_S0.5370.94
125_V161_F0.5340.94
41_P73_V0.5320.94
90_L93_R0.5320.94
42_R101_T0.5310.94
68_S175_L0.5280.94
32_D36_R0.5260.93
49_A67_G0.5190.93
66_I106_L0.5160.93
4_L64_L0.5140.93
70_Q154_E0.5130.93
9_T26_C0.5130.93
178_I182_Q0.5100.92
63_H111_S0.5070.92
50_Q109_F0.5050.92
64_L184_L0.5020.92
41_P71_V0.5020.92
12_W173_V0.5000.92
44_L80_G0.5000.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4jhcA 2 0.9897 100 0.023 Contact Map
1ex2A 2 0.9485 100 0.041 Contact Map
4oo0A 2 0.9794 100 0.042 Contact Map
4p0eA 2 0.9691 100 0.055 Contact Map
2p5xA 1 0.9691 100 0.057 Contact Map
2amhA 1 0.9536 100 0.06 Contact Map
4bnqA 2 0.8814 99.8 0.691 Contact Map
3tquA 2 0.866 99.6 0.748 Contact Map
1k7kA 1 0.8608 97.6 0.872 Contact Map
1b78A 2 0.8247 97.2 0.882 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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