IF2 - ECOLI - GREMLIN Contacts

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IF2 - Translation initiation factor IF-2

UniProt:	P0A705	Sequences: MTDVTIKTLAAERQTSVERLVQQFADAGIRKSADDSVSAQEKQTLIDHLNQKNSGPDKLTLQRKTRSTLNIPGTGGKSKSVQIEVRKKRTFVKRDPQEAERLAAEEQAQREAEEQARREAEESAKREAQQKAEREAAEQAKREAAEQAKREAAEKDKVSNQQDDMTKNAQAEKARREQEAAELKRKAEEEARRKLEEEARRVAEEARRMAEENKWTDNAEPTEDSSDYHVTTSQHARQAEDESDREVEGGRGRGRNAKAARPKKGNKHAESKADREEARAAVRGGKGGKRKGSSLQQGFQKPAQAVNRDVVIGETITVGELANKMAVKGSQVIKAMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEAVMSDRDTGAAAEPRAPVVTIMGHVDHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETENGMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAQVPVVVAVNKIDKPEADPDRVKNELSQYGILPEEWGGESQFVHVSAKAGTGIDELLDAILLQAEVLELKAVRKGMASGAVIESFLDKGRGPVATVLVREGTLHKGDIVLCGFEYGRVRAMRNELGQEVLEAGPSIPVEILGLSGVPAAGDEVTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMTEGEVHEVNIVLKADVQGSVEAISDSLLKLSTDEVKVKIIGSGVGGITETDATLAAASNAILVGFNVRADASARKVIEAESLDLRYYSVIYNLIDEVKAAMSGMLSPELKQQIIGLAEVRDVFKSPKFGAIAGCMVTEGVVKRHNPIRVLRDNVVIYEGELESLRRFKDDVNEVRNGMECGIGVKNYNDVRTGDVIEVFEIIEIQRTIA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10505
Length:	890 (810)
Sequences:	2422 (1923)
Seq/√Len:	67.6

ECOLI - IF2
BACSU - IF2
HALSA - IF2P

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
466_V	548_I	8.645	1.00
733_A	743_L	6.950	1.00
611_N	615_Q	5.193	1.00
839_E	880_F	4.849	1.00
592_H	619_E	4.757	1.00
438_G	553_E	4.677	1.00
802_D	873_T	4.588	1.00
540_G	543_E	4.434	1.00
480_I	517_Y	4.299	1.00
803_V	811_A	4.022	1.00
529_Q	547_A	3.596	1.00
695_A	701_V	3.574	1.00
821_V	856_R	3.505	1.00
841_E	866_K	3.454	1.00
827_P	841_E	3.222	1.00
830_V	865_V	3.144	1.00
413_S	538_G	3.110	1.00
793_Q	883_I	3.031	1.00
842_L	863_I	2.967	1.00
823_K	881_E	2.951	1.00
500_I	539_T	2.945	1.00
795_I	826_N	2.865	1.00
563_G	588_E	2.846	1.00
410_Y	538_G	2.775	1.00
498_N	535_A	2.702	1.00
704_I	774_L	2.666	1.00
136_A	140_A	2.665	1.00
799_E	874_G	2.663	1.00
38_S	41_E	2.662	1.00
160_N	164_D	2.661	1.00
434_E	439_M	2.639	1.00
511_K	532_H	2.625	1.00
410_Y	541_I	2.618	1.00
602_E	633_G	2.612	1.00
167_K	171_A	2.500	1.00
801_R	816_M	2.421	1.00
713_T	782_M	2.421	1.00
515_S	520_L	2.419	1.00
597_V	628_I	2.416	1.00
773_N	776_D	2.414	1.00
170_Q	174_A	2.408	1.00
779_K	783_S	2.395	1.00
142_R	146_E	2.385	1.00
175_R	179_E	2.385	1.00
715_E	887_R	2.376	1.00
497_V	530_F	2.356	1.00
472_D	502_K	2.336	1.00
818_T	876_V	2.332	1.00
388_E	562_K	2.292	1.00
803_V	812_I	2.289	1.00
197_E	201_R	2.277	1.00
309_D	366_I	2.272	1.00
171_A	175_R	2.271	1.00
564_M	645_R	2.268	1.00
133_E	137_A	2.255	1.00
432_H	624_I	2.197	1.00
461_A	568_A	2.183	1.00
162_Q	166_T	2.176	1.00
161_Q	165_M	2.159	1.00
159_S	163_D	2.158	1.00
511_K	523_E	2.154	1.00
728_I	745_G	2.139	1.00
191_A	195_L	2.118	1.00
798_A	822_V	2.116	1.00
551_Q	555_L	2.063	1.00
758_I	765_L	2.052	1.00
503_P	506_D	2.029	1.00
790_L	882_I	2.017	1.00
350_D	353_T	2.010	1.00
174_A	178_Q	1.982	1.00
309_D	364_K	1.967	1.00
163_D	167_K	1.963	1.00
756_K	760_A	1.951	1.00
497_V	532_H	1.942	1.00
484_Q	722_G	1.927	1.00
480_I	484_Q	1.923	1.00
607_R	612_E	1.923	1.00
135_E	139_Q	1.907	1.00
515_S	524_W	1.905	1.00
662_R	666_L	1.898	1.00
173_K	177_E	1.878	1.00
198_E	202_V	1.870	1.00
109_Q	112_A	1.857	1.00
537_A	540_G	1.855	1.00
112_A	116_A	1.846	1.00
184_K	188_E	1.843	1.00
506_D	512_N	1.842	1.00
156_D	160_N	1.830	1.00
199_A	203_A	1.811	1.00
494_V	548_I	1.808	1.00
800_V	811_A	1.804	1.00
166_T	170_Q	1.794	1.00
189_E	192_R	1.792	1.00
383_T	386_A	1.771	1.00
153_A	157_K	1.767	1.00
509_R	513_E	1.763	1.00
198_E	201_R	1.761	1.00
467_L	495_V	1.736	1.00
827_P	880_F	1.721	1.00
135_E	143_E	1.720	1.00
797_L	819_E	1.691	0.99
140_A	144_A	1.691	0.99
138_E	142_R	1.690	0.99
317_T	320_E	1.688	0.99
146_E	150_R	1.685	0.99
131_K	135_E	1.682	0.99
844_S	864_G	1.675	0.99
822_V	879_V	1.675	0.99
332_V	357_V	1.672	0.99
157_K	161_Q	1.667	0.99
283_R	286_K	1.666	0.99
145_A	149_K	1.665	0.99
147_Q	151_E	1.661	0.99
388_E	561_R	1.654	0.99
500_I	540_G	1.648	0.99
190_E	193_R	1.646	0.99
141_K	145_A	1.629	0.99
532_H	539_T	1.622	0.99
132_A	136_A	1.620	0.99
329_G	333_I	1.617	0.99
607_R	610_R	1.617	0.99
474_G	513_E	1.616	0.99
143_E	147_Q	1.613	0.99
197_E	200_R	1.610	0.99
518_G	521_P	1.604	0.99
156_D	159_S	1.595	0.99
172_E	176_R	1.590	0.99
282_V	285_G	1.583	0.99
122_E	126_R	1.581	0.99
793_Q	881_E	1.580	0.99
285_G	289_K	1.578	0.99
109_Q	113_E	1.577	0.99
359_E	364_K	1.575	0.99
807_P	864_G	1.570	0.99
321_L	325_M	1.570	0.99
189_E	193_R	1.566	0.99
119_E	123_S	1.566	0.99
806_S	809_F	1.562	0.99
830_V	868_Y	1.558	0.99
609_M	612_E	1.557	0.99
789_E	887_R	1.551	0.99
358_A	365_V	1.545	0.99
261_R	264_K	1.538	0.99
168_N	172_E	1.534	0.99
171_A	179_E	1.531	0.99
115_Q	120_A	1.529	0.99
676_N	679_A	1.529	0.99
432_H	439_M	1.523	0.99
812_I	864_G	1.520	0.99
123_S	127_E	1.518	0.99
63_R	67_S	1.506	0.99
521_P	530_F	1.504	0.99
58_K	61_L	1.502	0.99
149_K	153_A	1.497	0.99
373_L	376_A	1.496	0.99
382_D	560_V	1.492	0.99
386_A	560_V	1.491	0.99
389_P	438_G	1.485	0.99
768_Y	777_E	1.483	0.99
146_E	149_K	1.464	0.99
118_R	122_E	1.459	0.98
37_V	42_K	1.458	0.98
234_Q	238_Q	1.458	0.98
285_G	288_G	1.458	0.98
164_D	168_N	1.454	0.98
106_E	110_R	1.447	0.98
131_K	136_A	1.445	0.98
570_I	583_T	1.431	0.98
232_T	239_A	1.429	0.98
60_T	63_R	1.428	0.98
787_S	790_L	1.422	0.98
197_E	204_E	1.422	0.98
116_A	120_A	1.421	0.98
172_E	175_R	1.419	0.98
846_R	852_V	1.418	0.98
396_I	494_V	1.416	0.98
607_R	611_N	1.416	0.98
163_D	166_T	1.416	0.98
584_V	641_V	1.411	0.98
434_E	437_N	1.411	0.98
113_E	117_R	1.408	0.98
269_A	272_K	1.395	0.98
118_R	126_R	1.393	0.98
76_G	81_V	1.391	0.98
831_L	836_V	1.386	0.98
134_R	138_E	1.385	0.98
170_Q	173_K	1.378	0.98
237_R	241_D	1.377	0.98
265_G	269_A	1.375	0.98
162_Q	165_M	1.375	0.98
709_L	720_I	1.372	0.98
734_T	737_A	1.368	0.98
126_R	130_Q	1.367	0.98
179_E	183_L	1.363	0.98
122_E	125_K	1.355	0.98
42_K	46_I	1.350	0.97
193_R	198_E	1.349	0.97
828_I	865_V	1.348	0.97
830_V	871_V	1.347	0.97
733_A	758_I	1.345	0.97
522_E	529_Q	1.345	0.97
67_S	71_I	1.340	0.97
199_A	202_V	1.334	0.97
188_E	198_E	1.331	0.97
435_T	438_G	1.331	0.97
487_K	518_G	1.331	0.97
164_D	167_K	1.324	0.97
737_A	761_E	1.316	0.97
64_K	67_S	1.314	0.97
281_A	284_G	1.310	0.97
124_A	128_A	1.306	0.97
532_H	540_G	1.304	0.97
325_M	363_H	1.303	0.97
396_I	541_I	1.303	0.97
265_G	268_H	1.301	0.97
111_E	115_Q	1.299	0.97
264_K	267_K	1.294	0.97
169_A	173_K	1.294	0.97
161_Q	169_A	1.292	0.97
283_R	287_G	1.289	0.97
125_K	129_Q	1.289	0.97
440_I	494_V	1.288	0.97
133_E	136_A	1.288	0.97
130_Q	134_R	1.287	0.97
311_V	366_I	1.285	0.97
167_K	175_R	1.282	0.97
411_I	541_I	1.281	0.96
230_V	233_S	1.281	0.96
195_L	199_A	1.278	0.96
284_G	287_G	1.277	0.96
815_C	842_L	1.276	0.96
76_G	83_I	1.272	0.96
81_V	91_F	1.269	0.96
115_Q	119_E	1.269	0.96
839_E	877_I	1.267	0.96
794_I	819_E	1.267	0.96
137_A	140_A	1.267	0.96
800_V	813_A	1.264	0.96
134_R	139_Q	1.263	0.96
815_C	861_C	1.260	0.96
200_R	204_E	1.256	0.96
284_G	288_G	1.242	0.96
152_A	156_D	1.241	0.96
513_E	516_Q	1.236	0.96
822_V	863_I	1.234	0.96
66_R	70_N	1.233	0.96
109_Q	117_R	1.232	0.96
237_R	240_E	1.227	0.96
328_K	331_Q	1.227	0.96
73_G	81_V	1.226	0.95
141_K	144_A	1.224	0.95
765_L	846_R	1.220	0.95
194_K	198_E	1.220	0.95
165_M	169_A	1.218	0.95
236_A	239_A	1.217	0.95
190_E	194_K	1.215	0.95
144_A	148_A	1.214	0.95
705_S	709_L	1.211	0.95
85_V	89_R	1.209	0.95
81_V	84_E	1.198	0.95
863_I	877_I	1.197	0.95
79_K	87_K	1.195	0.95
176_R	179_E	1.195	0.95
190_E	195_L	1.193	0.95
597_V	631_L	1.192	0.95
415_K	542_D	1.191	0.95
607_R	614_G	1.190	0.95
193_R	196_E	1.190	0.95
596_I	651_R	1.190	0.95
88_K	93_K	1.181	0.94
615_Q	618_L	1.179	0.94
174_A	177_E	1.177	0.94
230_V	234_Q	1.175	0.94
687_H	787_S	1.169	0.94
115_Q	118_R	1.165	0.94
755_R	759_E	1.159	0.94
131_K	139_Q	1.159	0.94
190_E	198_E	1.156	0.94
117_R	121_E	1.154	0.94
235_H	238_Q	1.152	0.94
67_S	72_P	1.151	0.94
129_Q	133_E	1.150	0.94
162_Q	170_Q	1.149	0.94
258_K	262_P	1.148	0.94
617_V	626_V	1.145	0.94
117_R	125_K	1.145	0.94
170_Q	178_Q	1.145	0.94
121_E	125_K	1.144	0.93
188_E	197_E	1.144	0.93
68_T	71_I	1.143	0.93
689_V	785_M	1.142	0.93
523_E	532_H	1.139	0.93
800_V	871_V	1.135	0.93
114_E	118_R	1.132	0.93
840_G	865_V	1.130	0.93
149_K	152_A	1.130	0.93
232_T	236_A	1.127	0.93
147_Q	150_R	1.122	0.93
806_S	864_G	1.120	0.93
65_T	68_T	1.119	0.93
550_L	553_E	1.117	0.93
231_T	235_H	1.115	0.93
811_A	869_N	1.115	0.93
469_V	500_I	1.109	0.92
81_V	88_K	1.107	0.92
826_N	879_V	1.106	0.92
130_Q	137_A	1.104	0.92
233_S	236_A	1.103	0.92
266_N	269_A	1.103	0.92
118_R	121_E	1.100	0.92
204_E	208_R	1.100	0.92
490_Q	518_G	1.099	0.92
166_T	169_A	1.098	0.92
261_R	267_K	1.097	0.92
131_K	134_R	1.097	0.92
744_V	774_L	1.095	0.92
85_V	90_T	1.095	0.92
232_T	235_H	1.094	0.92
122_E	128_A	1.094	0.92
828_I	842_L	1.093	0.92
190_E	202_V	1.091	0.92
335_A	338_K	1.090	0.92
842_L	877_I	1.089	0.92
111_E	116_A	1.089	0.92
167_K	170_Q	1.088	0.92
529_Q	554_V	1.086	0.92
131_K	138_E	1.084	0.92
264_K	269_A	1.083	0.91
609_M	613_L	1.081	0.91
77_K	82_Q	1.081	0.91
856_R	859_M	1.080	0.91
776_D	780_A	1.078	0.91
809_F	846_R	1.077	0.91
65_T	69_L	1.077	0.91
76_G	80_S	1.075	0.91
233_S	240_E	1.073	0.91
76_G	79_K	1.070	0.91
475_V	530_F	1.069	0.91
468_V	533_V	1.068	0.91
157_K	162_Q	1.068	0.91
163_D	169_A	1.068	0.91
605_R	612_E	1.066	0.91
264_K	268_H	1.065	0.91
519_I	528_S	1.064	0.91
143_E	151_E	1.064	0.91
607_R	613_L	1.060	0.91
79_K	84_E	1.059	0.91
82_Q	87_K	1.055	0.90
770_V	774_L	1.054	0.90
92_V	96_P	1.054	0.90
261_R	270_E	1.054	0.90
137_A	141_K	1.053	0.90
120_A	124_A	1.053	0.90
593_K	618_L	1.052	0.90
146_E	152_A	1.051	0.90
266_N	273_A	1.049	0.90
287_G	290_R	1.048	0.90
121_E	129_Q	1.047	0.90
843_E	864_G	1.047	0.90
316_I	320_E	1.046	0.90
161_Q	176_R	1.045	0.90
115_Q	121_E	1.045	0.90
135_E	141_K	1.044	0.90
335_A	361_M	1.040	0.90
41_E	44_T	1.039	0.90
162_Q	169_A	1.039	0.90
124_A	130_Q	1.038	0.90
85_V	88_K	1.035	0.90
193_R	197_E	1.035	0.90
148_A	152_A	1.034	0.89
750_A	767_Y	1.033	0.89
177_E	183_L	1.032	0.89
715_E	787_S	1.032	0.89
153_A	161_Q	1.031	0.89
111_E	119_E	1.031	0.89
620_A	626_V	1.031	0.89
343_A	347_Q	1.030	0.89
66_R	69_L	1.030	0.89
126_R	134_R	1.029	0.89
815_C	863_I	1.028	0.89
831_L	834_N	1.027	0.89
196_E	202_V	1.025	0.89
865_V	877_I	1.024	0.89
789_E	885_I	1.023	0.89
61_L	67_S	1.021	0.89
263_K	266_N	1.020	0.89
123_S	126_R	1.020	0.89
646_D	649_K	1.019	0.89
236_A	241_D	1.018	0.89
81_V	85_V	1.017	0.89
73_G	78_S	1.017	0.89
798_A	879_V	1.016	0.89
158_V	171_A	1.014	0.89
608_A	612_E	1.013	0.88
112_A	115_Q	1.013	0.88
58_K	68_T	1.012	0.88
64_K	71_I	1.012	0.88
106_E	117_R	1.012	0.88
86_R	89_R	1.011	0.88
83_I	89_R	1.009	0.88
114_E	122_E	1.007	0.88
141_K	149_K	1.007	0.88
92_V	95_D	1.007	0.88
531_V	540_G	1.002	0.88
465_V	551_Q	0.998	0.88
165_M	168_N	0.997	0.88
89_R	93_K	0.995	0.88
82_Q	85_V	0.994	0.88
561_R	590_T	0.993	0.87
268_H	271_S	0.993	0.87
266_N	270_E	0.990	0.87
145_A	153_A	0.989	0.87
286_K	290_R	0.986	0.87
265_G	272_K	0.986	0.87
78_S	84_E	0.985	0.87
743_L	765_L	0.984	0.87
31_K	35_D	0.982	0.87
138_E	143_E	0.980	0.87
135_E	142_R	0.979	0.87
846_R	851_D	0.979	0.87
169_A	175_R	0.977	0.87
823_K	826_N	0.976	0.87
838_Y	865_V	0.974	0.86
198_E	204_E	0.974	0.86
601_F	658_Q	0.974	0.86
127_E	130_Q	0.973	0.86
56_P	59_L	0.972	0.86
605_R	609_M	0.972	0.86
77_K	81_V	0.971	0.86
122_E	135_E	0.970	0.86
110_R	113_E	0.970	0.86
160_N	168_N	0.969	0.86
118_R	124_A	0.966	0.86
659_G	663_E	0.964	0.86
269_A	273_A	0.964	0.86
816_M	859_M	0.964	0.86
90_T	94_R	0.963	0.86
61_L	66_R	0.963	0.86
286_K	289_K	0.962	0.86
331_Q	334_K	0.960	0.86
816_M	860_E	0.957	0.85
79_K	86_R	0.956	0.85
134_R	140_A	0.955	0.85
262_P	265_G	0.953	0.85
128_A	132_A	0.953	0.85
169_A	177_E	0.952	0.85
483_I	517_Y	0.952	0.85
801_R	859_M	0.951	0.85
129_Q	137_A	0.951	0.85
110_R	117_R	0.950	0.85
410_Y	537_A	0.949	0.85
188_E	194_K	0.947	0.85
715_E	768_Y	0.946	0.85
171_A	177_E	0.945	0.85
260_A	263_K	0.945	0.85
233_S	237_R	0.943	0.85
188_E	192_R	0.942	0.85
194_K	197_E	0.941	0.84
63_R	69_L	0.940	0.84
140_A	149_K	0.939	0.84
194_K	199_A	0.939	0.84
153_A	177_E	0.939	0.84
82_Q	86_R	0.938	0.84
168_N	171_A	0.937	0.84
27_A	42_K	0.937	0.84
156_D	161_Q	0.936	0.84
161_Q	167_K	0.935	0.84
159_S	167_K	0.934	0.84
117_R	122_E	0.932	0.84
64_K	68_T	0.931	0.84
374_E	377_V	0.931	0.84
142_R	150_R	0.928	0.84
79_K	83_I	0.928	0.84
238_Q	241_D	0.927	0.84
163_D	170_Q	0.925	0.83
266_N	272_K	0.923	0.83
610_R	613_L	0.923	0.83
58_K	69_L	0.923	0.83
132_A	135_E	0.923	0.83
128_A	140_A	0.922	0.83
798_A	815_C	0.921	0.83
201_R	204_E	0.921	0.83
195_L	198_E	0.920	0.83
188_E	191_A	0.920	0.83
133_E	141_K	0.919	0.83
189_E	200_R	0.919	0.83
188_E	193_R	0.919	0.83
655_L	659_G	0.918	0.83
267_K	270_E	0.916	0.83
838_Y	872_R	0.915	0.83
141_K	146_E	0.914	0.83
80_S	90_T	0.913	0.83
35_D	42_K	0.912	0.83
59_L	62_Q	0.910	0.82
259_A	263_K	0.910	0.82
77_K	84_E	0.909	0.82
164_D	172_E	0.908	0.82
258_K	261_R	0.908	0.82
159_S	171_A	0.907	0.82
144_A	157_K	0.906	0.82
333_I	337_M	0.906	0.82
60_T	64_K	0.906	0.82
144_A	147_Q	0.905	0.82
163_D	171_A	0.904	0.82
278_A	281_A	0.904	0.82
275_R	279_R	0.904	0.82
132_A	138_E	0.902	0.82
795_I	881_E	0.902	0.82
68_T	72_P	0.898	0.82
139_Q	144_A	0.896	0.81
411_I	545_L	0.896	0.81
126_R	132_A	0.895	0.81
344_T	347_Q	0.894	0.81
600_G	604_G	0.894	0.81
137_A	142_R	0.894	0.81
231_T	238_Q	0.893	0.81
533_V	536_K	0.893	0.81
75_G	78_S	0.891	0.81
61_L	68_T	0.891	0.81
58_K	63_R	0.891	0.81
134_R	142_R	0.891	0.81
259_A	262_P	0.889	0.81
139_Q	143_E	0.889	0.81
512_N	515_S	0.889	0.81
733_A	765_L	0.889	0.81
159_S	162_Q	0.889	0.81
142_R	148_A	0.889	0.81
90_T	93_K	0.888	0.81
574_L	580_P	0.888	0.81
791_K	885_I	0.887	0.81
465_V	482_A	0.887	0.81
80_S	86_R	0.885	0.81
427_H	697_V	0.885	0.81
148_A	151_E	0.885	0.81
511_K	530_F	0.885	0.81
157_K	163_D	0.882	0.80
777_E	780_A	0.882	0.80
160_N	163_D	0.881	0.80
355_Q	365_V	0.880	0.80
733_A	763_L	0.880	0.80
138_E	144_A	0.878	0.80
437_N	546_D	0.876	0.80
169_A	172_E	0.876	0.80
134_R	141_K	0.876	0.80
111_E	114_E	0.876	0.80
687_H	789_E	0.874	0.80
78_S	82_Q	0.874	0.80
165_M	177_E	0.873	0.80
566_S	588_E	0.872	0.80
797_L	876_V	0.871	0.80
196_E	200_R	0.870	0.80
847_R	855_V	0.868	0.79
79_K	82_Q	0.865	0.79
125_K	133_E	0.865	0.79
144_A	150_R	0.863	0.79
120_A	169_A	0.863	0.79
268_H	272_K	0.863	0.79
139_Q	147_Q	0.862	0.79
139_Q	142_R	0.861	0.79
234_Q	237_R	0.861	0.79
127_E	134_R	0.860	0.79
783_S	886_Q	0.857	0.78
749_R	835_V	0.856	0.78
158_V	170_Q	0.855	0.78
335_A	339_L	0.855	0.78
91_F	95_D	0.852	0.78
235_H	241_D	0.852	0.78
85_V	91_F	0.851	0.78
82_Q	89_R	0.850	0.78
84_E	91_F	0.850	0.78
795_I	879_V	0.848	0.78
674_L	781_A	0.845	0.78
263_K	268_H	0.843	0.77
115_Q	126_R	0.843	0.77
191_A	196_E	0.840	0.77
569_V	584_V	0.840	0.77
798_A	863_I	0.840	0.77
620_A	624_I	0.839	0.77
113_E	116_A	0.837	0.77
140_A	145_A	0.837	0.77
81_V	87_K	0.836	0.77
268_H	273_A	0.836	0.77
484_Q	487_K	0.834	0.77
156_D	162_Q	0.833	0.77
167_K	173_K	0.833	0.77
605_R	610_R	0.832	0.76
134_R	137_A	0.832	0.76
117_R	123_S	0.830	0.76
608_A	611_N	0.830	0.76
233_S	239_A	0.829	0.76
137_A	145_A	0.828	0.76
701_V	723_S	0.828	0.76
161_Q	164_D	0.827	0.76
60_T	68_T	0.826	0.76
57_D	63_R	0.825	0.76
132_A	140_A	0.825	0.76
816_M	857_N	0.824	0.76
116_A	121_E	0.822	0.76
487_K	517_Y	0.822	0.76
688_E	719_K	0.822	0.76
798_A	826_N	0.821	0.75
173_K	179_E	0.819	0.75
79_K	90_T	0.818	0.75
64_K	72_P	0.818	0.75
266_N	271_S	0.817	0.75
146_E	151_E	0.817	0.75
707_S	775_I	0.817	0.75
130_Q	133_E	0.816	0.75
133_E	140_A	0.815	0.75
220_E	235_H	0.814	0.75
196_E	199_A	0.814	0.75
259_A	267_K	0.814	0.75
386_A	562_K	0.814	0.75
137_A	147_Q	0.812	0.75
80_S	91_F	0.811	0.75
132_A	137_A	0.810	0.74
519_I	529_Q	0.810	0.74
805_K	811_A	0.809	0.74
686_V	717_K	0.809	0.74
175_R	178_Q	0.807	0.74
59_L	69_L	0.806	0.74
188_E	202_V	0.805	0.74
608_A	629_L	0.803	0.74
204_E	209_M	0.802	0.74
464_I	552_A	0.802	0.74
61_L	64_K	0.802	0.74
63_R	66_R	0.800	0.74
142_R	145_A	0.800	0.74
289_K	466_V	0.799	0.73
574_L	634_V	0.798	0.73
127_E	131_K	0.798	0.73
120_A	139_Q	0.798	0.73
605_R	611_N	0.797	0.73
469_V	498_N	0.796	0.73
168_N	173_K	0.796	0.73
158_V	162_Q	0.795	0.73
494_V	531_V	0.795	0.73
59_L	63_R	0.795	0.73
560_V	563_G	0.795	0.73
192_R	200_R	0.794	0.73
140_A	143_E	0.794	0.73
122_E	130_Q	0.793	0.73
83_I	86_R	0.793	0.73
382_D	386_A	0.792	0.73
660_K	663_E	0.791	0.73
58_K	67_S	0.790	0.73
110_R	114_E	0.789	0.73
83_I	90_T	0.788	0.72
264_K	270_E	0.787	0.72
506_D	509_R	0.787	0.72
724_G	729_T	0.785	0.72
672_S	763_L	0.784	0.72
29_I	41_E	0.784	0.72
842_L	865_V	0.784	0.72
231_T	236_A	0.782	0.72
200_R	203_A	0.781	0.72
757_V	761_E	0.781	0.72
159_S	164_D	0.778	0.71
280_A	283_R	0.778	0.71
172_E	183_L	0.777	0.71
296_Q	299_F	0.777	0.71
145_A	148_A	0.777	0.71
189_E	197_E	0.776	0.71
221_P	236_A	0.776	0.71
156_D	164_D	0.776	0.71
89_R	92_V	0.775	0.71
235_H	239_A	0.774	0.71
89_R	95_D	0.773	0.71
843_E	866_K	0.772	0.71
86_R	94_R	0.772	0.71
66_R	71_I	0.771	0.71
805_K	808_K	0.771	0.71
59_L	64_K	0.770	0.71
133_E	138_E	0.769	0.71
62_Q	65_T	0.769	0.71
580_P	634_V	0.769	0.71
173_K	178_Q	0.768	0.70
113_E	121_E	0.767	0.70
65_T	70_N	0.767	0.70
539_T	543_E	0.767	0.70
190_E	196_E	0.765	0.70
605_R	613_L	0.763	0.70
118_R	128_A	0.762	0.70
150_R	175_R	0.762	0.70
192_R	198_E	0.761	0.70
27_A	35_D	0.761	0.70
71_I	76_G	0.761	0.70
109_Q	118_R	0.760	0.70
117_R	126_R	0.759	0.70
259_A	264_K	0.759	0.70
415_K	418_S	0.759	0.70
198_E	203_A	0.759	0.70
67_S	70_N	0.758	0.69
262_P	268_H	0.756	0.69
76_G	88_K	0.756	0.69
599_C	641_V	0.755	0.69
84_E	89_R	0.754	0.69
602_E	632_S	0.754	0.69
232_T	240_E	0.754	0.69
54_S	63_R	0.754	0.69
138_E	145_A	0.753	0.69
259_A	268_H	0.753	0.69
609_M	628_I	0.752	0.69
391_A	439_M	0.752	0.69
63_R	68_T	0.752	0.69
621_G	624_I	0.751	0.69
672_S	677_M	0.751	0.69
57_D	60_T	0.750	0.69
415_K	613_L	0.749	0.69
88_K	91_F	0.748	0.68
196_E	208_R	0.748	0.68
512_N	518_G	0.747	0.68
123_S	136_A	0.745	0.68
693_L	706_D	0.745	0.68
142_R	149_K	0.744	0.68
460_Q	490_Q	0.744	0.68
230_V	236_A	0.744	0.68
188_E	204_E	0.744	0.68
116_A	119_E	0.742	0.68
373_L	377_V	0.742	0.68
706_D	710_K	0.741	0.68
318_V	343_A	0.740	0.68
130_Q	138_E	0.740	0.68
606_V	628_I	0.739	0.68
78_S	81_V	0.739	0.68
235_H	240_E	0.739	0.68
316_I	324_K	0.738	0.67
263_K	273_A	0.736	0.67
140_A	148_A	0.736	0.67
236_A	240_E	0.735	0.67
84_E	94_R	0.734	0.67
136_A	143_E	0.732	0.67
337_M	342_M	0.730	0.67
73_G	76_G	0.730	0.67
132_A	152_A	0.730	0.67
706_D	709_L	0.729	0.66
267_K	271_S	0.728	0.66
86_R	90_T	0.727	0.66
560_V	588_E	0.727	0.66
75_G	81_V	0.726	0.66
91_F	94_R	0.726	0.66
293_S	297_Q	0.724	0.66
76_G	89_R	0.724	0.66
127_E	143_E	0.723	0.66
138_E	141_K	0.723	0.66
84_E	90_T	0.721	0.66
349_I	354_A	0.720	0.66
156_D	166_T	0.720	0.66
111_E	120_A	0.720	0.66
411_I	689_V	0.720	0.66
842_L	879_V	0.719	0.65
838_Y	867_N	0.718	0.65
105_E	109_Q	0.718	0.65
812_I	852_V	0.718	0.65
833_D	836_V	0.717	0.65
670_Q	676_N	0.716	0.65
339_L	356_L	0.716	0.65
168_N	176_R	0.715	0.65
73_G	79_K	0.715	0.65
480_I	515_S	0.715	0.65
295_L	298_G	0.715	0.65
231_T	237_R	0.715	0.65
599_C	602_E	0.715	0.65
435_T	440_I	0.714	0.65
798_A	864_G	0.714	0.65
189_E	194_K	0.713	0.65
532_H	543_E	0.713	0.65
58_K	71_I	0.711	0.65
163_D	175_R	0.711	0.65
443_L	631_L	0.710	0.64
387_A	560_V	0.710	0.64
531_V	547_A	0.710	0.64
531_V	543_E	0.710	0.64
290_R	294_S	0.709	0.64
81_V	89_R	0.708	0.64
124_A	127_E	0.707	0.64
83_I	92_V	0.707	0.64
106_E	112_A	0.706	0.64
233_S	238_Q	0.706	0.64
171_A	174_A	0.705	0.64
264_K	273_A	0.703	0.64
145_A	156_D	0.703	0.64
158_V	164_D	0.703	0.64
407_L	533_V	0.701	0.63
573_F	583_T	0.701	0.63
609_M	620_A	0.699	0.63
57_D	71_I	0.699	0.63
51_Q	54_S	0.698	0.63
160_N	166_T	0.698	0.63
127_E	142_R	0.697	0.63
564_M	592_H	0.697	0.63
189_E	196_E	0.697	0.63
663_E	667_A	0.697	0.63
139_Q	183_L	0.696	0.63
578_R	581_V	0.696	0.63
152_A	160_N	0.696	0.63
507_P	532_H	0.694	0.63
520_L	528_S	0.694	0.63
119_E	122_E	0.691	0.62
116_A	122_E	0.690	0.62
157_K	165_M	0.690	0.62
61_L	71_I	0.689	0.62
140_A	179_E	0.688	0.62
826_N	853_N	0.688	0.62
230_V	235_H	0.687	0.62
260_A	264_K	0.687	0.62
493_V	519_I	0.686	0.62
133_E	139_Q	0.686	0.62
333_I	346_N	0.686	0.62
267_K	272_K	0.686	0.62
278_A	287_G	0.685	0.62
189_E	204_E	0.685	0.62
357_V	361_M	0.685	0.62
176_R	184_K	0.684	0.62
56_P	69_L	0.684	0.62
69_L	72_P	0.683	0.61
264_K	272_K	0.682	0.61
158_V	161_Q	0.682	0.61
807_P	846_R	0.681	0.61
193_R	202_V	0.681	0.61
171_A	183_L	0.681	0.61
94_R	106_E	0.681	0.61
679_A	683_E	0.681	0.61
278_A	283_R	0.680	0.61
120_A	126_R	0.680	0.61
176_R	183_L	0.679	0.61
89_R	94_R	0.679	0.61
288_G	294_S	0.679	0.61
437_N	549_L	0.678	0.61
158_V	163_D	0.677	0.61
166_T	172_E	0.677	0.61
597_V	641_V	0.677	0.61
84_E	88_K	0.677	0.61
129_Q	132_A	0.676	0.61
184_K	189_E	0.674	0.60
325_M	328_K	0.674	0.60
232_T	238_Q	0.673	0.60
27_A	48_H	0.673	0.60
56_P	60_T	0.672	0.60
75_G	79_K	0.672	0.60
65_T	80_S	0.672	0.60
196_E	201_R	0.670	0.60
128_A	134_R	0.670	0.60
65_T	71_I	0.670	0.60
264_K	271_S	0.669	0.60
234_Q	239_A	0.669	0.60
197_E	202_V	0.668	0.60
166_T	171_A	0.668	0.60
233_S	241_D	0.667	0.60
62_Q	69_L	0.667	0.60
265_G	273_A	0.665	0.59
189_E	202_V	0.664	0.59
171_A	176_R	0.664	0.59
782_M	786_L	0.664	0.59
592_H	595_D	0.663	0.59
812_I	844_S	0.663	0.59
135_E	138_E	0.663	0.59
639_D	863_I	0.662	0.59
109_Q	114_E	0.662	0.59
170_Q	176_R	0.661	0.59
339_L	353_T	0.660	0.59
777_E	791_K	0.660	0.59
80_S	89_R	0.660	0.59
188_E	196_E	0.660	0.59
80_S	88_K	0.660	0.59
105_E	111_E	0.660	0.59
234_Q	240_E	0.659	0.59
508_D	524_W	0.658	0.59
232_T	237_R	0.658	0.59
136_A	158_V	0.658	0.59
169_A	179_E	0.658	0.59
356_L	359_E	0.658	0.59
137_A	143_E	0.657	0.58
260_A	270_E	0.657	0.58
173_K	176_R	0.656	0.58
88_K	92_V	0.656	0.58
112_A	117_R	0.656	0.58
807_P	810_G	0.654	0.58
262_P	273_A	0.653	0.58
184_K	190_E	0.652	0.58
803_V	843_E	0.652	0.58
468_V	720_I	0.651	0.58
164_D	171_A	0.651	0.58
475_V	513_E	0.650	0.58
628_I	631_L	0.650	0.58
79_K	92_V	0.649	0.58
351_Q	354_A	0.648	0.57
161_Q	166_T	0.648	0.57
145_A	150_R	0.647	0.57
435_T	545_L	0.647	0.57
126_R	129_Q	0.646	0.57
610_R	616_E	0.645	0.57
164_D	176_R	0.645	0.57
73_G	77_K	0.643	0.57
114_E	124_A	0.642	0.57
490_Q	554_V	0.642	0.57
77_K	88_K	0.642	0.57
783_S	790_L	0.641	0.57
111_E	134_R	0.640	0.56
196_E	203_A	0.640	0.56
129_Q	135_E	0.639	0.56
831_L	835_V	0.637	0.56
190_E	204_E	0.637	0.56
177_E	196_E	0.635	0.56
37_V	45_L	0.634	0.56
128_A	131_K	0.634	0.56
265_G	271_S	0.633	0.56
55_G	60_T	0.633	0.56
283_R	290_R	0.632	0.56
511_K	515_S	0.631	0.55
687_H	716_V	0.631	0.55
133_E	148_A	0.631	0.55
191_A	194_K	0.630	0.55
523_E	606_V	0.630	0.55
120_A	123_S	0.630	0.55
290_R	295_L	0.630	0.55
508_D	532_H	0.629	0.55
313_G	324_K	0.629	0.55
871_V	875_D	0.628	0.55
281_A	285_G	0.626	0.55
127_E	135_E	0.626	0.55
520_L	530_F	0.625	0.55
314_E	351_Q	0.625	0.55
161_Q	170_Q	0.623	0.54
355_Q	359_E	0.623	0.54
138_E	146_E	0.623	0.54
257_A	262_P	0.622	0.54
142_R	165_M	0.621	0.54
84_E	87_K	0.621	0.54
705_S	720_I	0.621	0.54
587_R	623_S	0.620	0.54
158_V	166_T	0.620	0.54
231_T	234_Q	0.620	0.54
157_K	168_N	0.619	0.54
790_L	884_E	0.619	0.54
140_A	147_Q	0.619	0.54
291_K	296_Q	0.619	0.54
158_V	165_M	0.618	0.54
500_I	504_E	0.618	0.54
75_G	80_S	0.618	0.54
565_A	591_L	0.617	0.54
183_L	198_E	0.616	0.54
116_A	126_R	0.616	0.54
190_E	197_E	0.616	0.54
123_S	128_A	0.615	0.54
165_M	172_E	0.615	0.54
262_P	266_N	0.614	0.53
172_E	179_E	0.613	0.53
86_R	93_K	0.612	0.53
73_G	83_I	0.612	0.53
114_E	120_A	0.612	0.53
396_I	548_I	0.611	0.53
165_M	171_A	0.611	0.53
115_Q	125_K	0.611	0.53
119_E	126_R	0.611	0.53
118_R	134_R	0.609	0.53
125_K	145_A	0.609	0.53
833_D	872_R	0.609	0.53
44_T	47_D	0.608	0.53
119_E	168_N	0.607	0.53
566_S	587_R	0.605	0.52
167_K	172_E	0.605	0.52
125_K	135_E	0.602	0.52
738_A	754_A	0.602	0.52
230_V	239_A	0.602	0.52
132_A	150_R	0.601	0.52
111_E	124_A	0.601	0.52
261_R	272_K	0.600	0.52
812_I	851_D	0.600	0.52
129_Q	201_R	0.600	0.52
153_A	174_A	0.599	0.52
132_A	141_K	0.597	0.51
134_R	149_K	0.597	0.51
197_E	203_A	0.596	0.51
114_E	126_R	0.596	0.51
199_A	204_E	0.596	0.51
169_A	176_R	0.595	0.51
129_Q	143_E	0.595	0.51
195_L	203_A	0.595	0.51
135_E	161_Q	0.595	0.51
136_A	144_A	0.594	0.51
60_T	67_S	0.593	0.51
132_A	143_E	0.591	0.51
117_R	120_A	0.591	0.51
396_I	465_V	0.590	0.51
352_E	355_Q	0.590	0.51
794_I	797_L	0.590	0.51
122_E	127_E	0.589	0.50
55_G	64_K	0.589	0.50
170_Q	175_R	0.588	0.50
710_K	809_F	0.587	0.50
132_A	142_R	0.587	0.50
61_L	72_P	0.586	0.50
606_V	675_E	0.586	0.50
56_P	65_T	0.586	0.50
705_S	723_S	0.585	0.50
795_I	885_I	0.585	0.50
145_A	160_N	0.585	0.50
847_R	859_M	0.585	0.50
316_I	354_A	0.585	0.50
802_D	848_F	0.585	0.50
819_E	857_N	0.584	0.50
127_E	133_E	0.584	0.50
153_A	165_M	0.583	0.50
221_P	234_Q	0.582	0.50
284_G	291_K	0.581	0.49
56_P	61_L	0.581	0.49
690_N	825_H	0.581	0.49
115_Q	130_Q	0.581	0.49
133_E	149_K	0.580	0.49
681_M	684_G	0.580	0.49
139_Q	174_A	0.580	0.49
110_R	118_R	0.580	0.49
500_I	537_A	0.580	0.49
221_P	240_E	0.579	0.49
680_N	740_N	0.579	0.49
722_G	848_F	0.579	0.49
563_G	590_T	0.578	0.49
189_E	199_A	0.578	0.49
482_A	485_H	0.578	0.49
191_A	200_R	0.577	0.49
162_Q	167_K	0.577	0.49
114_E	138_E	0.577	0.49
528_S	547_A	0.577	0.49
130_Q	148_A	0.576	0.49
78_S	87_K	0.576	0.49
162_Q	177_E	0.576	0.49
87_K	91_F	0.576	0.49
411_I	785_M	0.575	0.49
163_D	168_N	0.574	0.49
126_R	135_E	0.574	0.49
139_Q	157_K	0.574	0.49
351_Q	367_L	0.574	0.49
191_A	201_R	0.573	0.49
83_I	91_F	0.573	0.49
811_A	871_V	0.572	0.48
63_R	71_I	0.571	0.48
277_E	280_A	0.571	0.48
716_V	782_M	0.571	0.48
165_M	173_K	0.570	0.48
720_I	857_N	0.570	0.48
143_E	150_R	0.569	0.48
606_V	612_E	0.568	0.48
705_S	776_D	0.567	0.48
751_D	754_A	0.566	0.48
727_G	834_N	0.565	0.48
441_T	624_I	0.564	0.47
676_N	680_N	0.564	0.47
312_I	316_I	0.564	0.47
82_Q	90_T	0.563	0.47
828_I	879_V	0.563	0.47
513_E	627_E	0.562	0.47
282_V	287_G	0.561	0.47
119_E	143_E	0.561	0.47
57_D	61_L	0.560	0.47
127_E	137_A	0.559	0.47
605_R	608_A	0.558	0.47
603_Y	632_S	0.558	0.47
345_I	350_D	0.557	0.47
168_N	175_R	0.556	0.47
152_A	167_K	0.556	0.47
153_A	169_A	0.556	0.47
260_A	265_G	0.556	0.47
262_P	270_E	0.555	0.46
692_V	743_L	0.554	0.46
126_R	138_E	0.554	0.46
460_Q	592_H	0.553	0.46
140_A	146_E	0.552	0.46
821_V	854_E	0.552	0.46
742_I	781_A	0.552	0.46
806_S	812_I	0.552	0.46
114_E	117_R	0.552	0.46
75_G	82_Q	0.551	0.46
162_Q	194_K	0.551	0.46
115_Q	123_S	0.551	0.46
125_K	130_Q	0.551	0.46
131_K	140_A	0.551	0.46
725_V	769_S	0.550	0.46
294_S	297_Q	0.549	0.46
692_V	724_G	0.549	0.46
66_R	95_D	0.548	0.46
231_T	239_A	0.548	0.46
125_K	128_A	0.548	0.46
73_G	89_R	0.548	0.46
495_V	528_S	0.547	0.45
191_A	197_E	0.546	0.45
113_E	130_Q	0.546	0.45
55_G	65_T	0.545	0.45
261_R	269_A	0.545	0.45
260_A	269_A	0.544	0.45
134_R	167_K	0.543	0.45
165_M	170_Q	0.543	0.45
34_D	37_V	0.543	0.45
288_G	295_L	0.543	0.45
157_K	160_N	0.542	0.45
145_A	201_R	0.542	0.45
147_Q	165_M	0.542	0.45
139_Q	149_K	0.542	0.45
112_A	138_E	0.540	0.45
202_V	209_M	0.540	0.45
477_P	701_V	0.540	0.45
37_V	44_T	0.540	0.45
667_A	670_Q	0.539	0.44
432_H	441_T	0.539	0.44
822_V	842_L	0.539	0.44
722_G	732_D	0.539	0.44
190_E	199_A	0.539	0.44
85_V	95_D	0.538	0.44
191_A	198_E	0.538	0.44
84_E	92_V	0.537	0.44
330_S	540_G	0.537	0.44
120_A	140_A	0.536	0.44
188_E	201_R	0.536	0.44
117_R	124_A	0.536	0.44
121_E	127_E	0.535	0.44
517_Y	528_S	0.535	0.44
134_R	143_E	0.535	0.44
697_V	766_R	0.535	0.44
523_E	540_G	0.535	0.44
110_R	115_Q	0.535	0.44
80_S	135_E	0.533	0.44
58_K	64_K	0.532	0.44
130_Q	146_E	0.531	0.44
140_A	150_R	0.531	0.44
134_R	157_K	0.531	0.44
231_T	241_D	0.531	0.44
281_A	288_G	0.530	0.43
123_S	138_E	0.529	0.43
137_A	144_A	0.528	0.43
573_F	627_E	0.528	0.43
673_K	676_N	0.528	0.43
195_L	201_R	0.528	0.43
833_D	837_I	0.527	0.43
278_A	282_V	0.527	0.43
549_L	785_M	0.527	0.43
95_D	106_E	0.526	0.43
189_E	198_E	0.526	0.43
32_S	35_D	0.526	0.43
122_E	133_E	0.526	0.43
184_K	194_K	0.525	0.43
583_T	586_V	0.524	0.43
59_L	68_T	0.524	0.43
281_A	289_K	0.524	0.43
664_V	667_A	0.523	0.43
809_F	818_T	0.523	0.43
59_L	65_T	0.521	0.42
114_E	142_R	0.521	0.42
389_P	556_E	0.521	0.42
846_R	853_N	0.521	0.42
163_D	178_Q	0.521	0.42
120_A	132_A	0.521	0.42
121_E	141_K	0.521	0.42
136_A	141_K	0.520	0.42
118_R	130_Q	0.520	0.42
261_R	266_N	0.520	0.42
111_E	176_R	0.519	0.42
112_A	125_K	0.519	0.42
144_A	162_Q	0.518	0.42
271_S	274_D	0.518	0.42
41_E	46_I	0.517	0.42
641_V	778_V	0.517	0.42
281_A	291_K	0.517	0.42
69_L	73_G	0.517	0.42
193_R	209_M	0.517	0.42
576_K	793_Q	0.516	0.42
259_A	266_N	0.516	0.42
190_E	203_A	0.516	0.42
779_K	882_I	0.515	0.42
609_M	614_G	0.515	0.42
600_G	603_Y	0.515	0.42
646_D	760_A	0.514	0.42
127_E	157_K	0.514	0.42
128_A	148_A	0.514	0.42
88_K	94_R	0.513	0.41
850_D	853_N	0.513	0.41
73_G	109_Q	0.513	0.41
687_H	713_T	0.513	0.41
289_K	293_S	0.513	0.41
189_E	209_M	0.512	0.41
230_V	237_R	0.512	0.41
791_K	883_I	0.512	0.41
220_E	265_G	0.511	0.41
794_I	831_L	0.510	0.41
188_E	199_A	0.510	0.41
396_I	760_A	0.509	0.41
136_A	146_E	0.509	0.41
209_M	221_P	0.508	0.41
307_N	318_V	0.508	0.41
31_K	39_A	0.508	0.41
73_G	91_F	0.508	0.41
85_V	93_K	0.506	0.41
651_R	655_L	0.506	0.41
307_N	363_H	0.506	0.41
130_Q	144_A	0.505	0.41
80_S	93_K	0.504	0.40
411_I	793_Q	0.504	0.40
118_R	129_Q	0.504	0.40
128_A	159_S	0.504	0.40
293_S	296_Q	0.504	0.40
113_E	125_K	0.503	0.40
285_G	290_R	0.503	0.40
515_S	521_P	0.503	0.40
60_T	69_L	0.502	0.40
58_K	66_R	0.502	0.40
131_K	176_R	0.502	0.40
184_K	201_R	0.502	0.40
164_D	170_Q	0.502	0.40
522_E	547_A	0.501	0.40
311_V	368_R	0.501	0.40
312_I	358_A	0.501	0.40
120_A	130_Q	0.501	0.40
137_A	152_A	0.500	0.40
96_P	115_Q	0.500	0.40
395_T	492_P	0.500	0.40
47_D	50_N	0.500	0.40

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1zo1I	1	0.5629	100	0.494	Contact Map
3j4jA	1	0.636	100	0.498	Contact Map
3izyP	1	0.5551	100	0.507	Contact Map
3wbiA	1	0.5247	100	0.541	Contact Map
4n3nA	2	0.5315	100	0.543	Contact Map
4upyB	1	0.564	100	0.548	Contact Map
1g7sA	1	0.5258	100	0.559	Contact Map
4kjzA	1	0.527	100	0.612	Contact Map
4n3sA	1	0.4169	100	0.639	Contact Map
4b43A	1	0.3854	100	0.776	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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