GREMLIN Database
HTPG - Chaperone protein HtpG
UniProt: P0A6Z3 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10461
Length: 624 (602)
Sequences: 3008 (1646)
Seq/√Len: 67.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
150_N166_D5.5001.00
74_R185_D5.3541.00
79_S175_E4.9981.00
140_R177_T4.9721.00
367_D370_K4.5581.00
94_L139_V4.5031.00
435_A441_A4.0531.00
247_K259_D3.9831.00
136_K155_E3.8541.00
71_K189_D3.8001.00
186_E192_R3.5871.00
70_D73_K3.4551.00
515_V593_V3.3811.00
509_T513_D3.3441.00
422_R456_E3.3041.00
418_D421_S3.2901.00
598_D617_R3.1951.00
64_R209_E3.1111.00
140_R153_F3.0751.00
67_V197_I3.0421.00
90_V141_T3.0391.00
417_E475_F3.0341.00
241_I245_E3.0301.00
251_K259_D3.0091.00
516_K525_D2.9771.00
474_E477_G2.9521.00
138_T155_E2.9501.00
417_E476_D2.8751.00
90_V152_V2.8421.00
506_K509_T2.8201.00
194_R225_E2.7731.00
192_R195_S2.7531.00
513_D517_A2.7371.00
499_E502_K2.7081.00
406_H454_G2.6801.00
86_T143_A2.6571.00
135_D182_E2.6251.00
398_K417_E2.5821.00
88_D92_D2.5801.00
405_T456_E2.5611.00
36_I197_I2.5411.00
5_E87_R2.5371.00
140_R167_I2.5331.00
197_I227_I2.4731.00
140_R175_E2.4691.00
591_E620_Q2.4561.00
89_E143_A2.4301.00
28_K184_E2.4201.00
502_K506_K2.4141.00
151_G167_I2.3891.00
438_Y442_K2.3791.00
414_V422_R2.3751.00
68_S79_S2.3551.00
138_T179_H2.3521.00
153_F165_A2.3521.00
190_D194_R2.3041.00
136_K179_H2.3011.00
397_A472_L2.3001.00
242_T245_E2.2981.00
404_S458_L2.2881.00
43_A63_L2.2781.00
405_T459_L2.2431.00
325_I352_L2.1521.00
524_K542_D2.0851.00
104_S107_E2.0851.00
243_D263_W2.0771.00
135_D179_H2.0751.00
500_S503_E2.0661.00
515_V570_L2.0641.00
49_R143_A2.0561.00
364_A401_R1.9991.00
243_D247_K1.9991.00
523_V526_V1.9971.00
66_R224_W1.9801.00
610_D613_L1.9491.00
505_E509_T1.9291.00
209_E226_K1.9261.00
502_K505_E1.9031.00
180_L188_L1.9001.00
69_F193_V1.8981.00
138_T153_F1.8931.00
29_E192_R1.8901.00
429_K479_P1.8721.00
247_K263_W1.8641.00
373_T376_Q1.8631.00
429_K481_Q1.8611.00
517_A520_G1.8511.00
136_K157_A1.8481.00
549_Q552_K1.8331.00
450_L483_V1.8241.00
283_Q377_Q1.7891.00
474_E479_P1.7821.00
77_T175_E1.7581.00
364_A415_S1.7511.00
244_E248_E1.7491.00
169_K175_E1.7451.00
66_R209_E1.7451.00
417_E421_S1.7311.00
247_K260_P1.7281.00
404_S414_V1.7191.00
134_A178_L1.7151.00
401_R415_S1.7101.00
372_Q412_Q1.6960.99
67_V76_L1.6900.99
130_A137_V1.6870.99
404_S456_E1.6780.99
258_N283_Q1.6720.99
417_E420_V1.6560.99
370_K373_T1.6540.99
209_E224_W1.6410.99
616_R620_Q1.6310.99
282_S373_T1.6210.99
522_R594_E1.6150.99
368_A418_D1.6040.99
518_L593_V1.6030.99
414_V456_E1.5990.99
155_E163_T1.5990.99
75_T177_T1.5980.99
424_K454_G1.5970.99
321_V356_V1.5780.99
138_T177_T1.5770.99
99_K104_S1.5670.99
78_I176_I1.5670.99
398_K475_F1.5610.99
66_R79_S1.5590.99
590_S594_E1.5530.99
423_M478_K1.5510.99
15_Q103_K1.5420.99
151_G170_E1.5420.99
369_E373_T1.5410.99
211_E224_W1.5360.99
499_E503_E1.5350.99
92_D104_S1.5340.99
250_Y256_D1.5300.99
420_V478_K1.5250.99
246_Y265_H1.5230.99
403_A413_T1.5190.99
233_L241_I1.5170.99
362_K366_D1.5010.99
6_T163_T1.4980.99
146_E150_N1.4930.99
35_L178_L1.4910.99
102_T119_L1.4890.99
141_T164_V1.4890.99
368_A372_Q1.4730.99
67_V227_I1.4730.99
146_E149_E1.4680.98
469_M480_F1.4630.98
71_K188_L1.4590.98
420_V476_D1.4560.98
74_R182_E1.4430.98
32_L78_I1.4410.98
67_V193_V1.4360.98
294_K311_E1.4330.98
89_E92_D1.4300.98
90_V94_L1.4300.98
577_V596_L1.4230.98
135_D181_R1.4170.98
537_A596_L1.4080.98
267_R275_T1.4070.98
5_E91_I1.3940.98
398_K476_D1.3850.98
29_E187_F1.3800.98
450_L488_E1.3790.98
403_A411_A1.3690.98
447_L483_V1.3610.98
280_I360_L1.3590.98
236_R245_E1.3580.97
86_T89_E1.3490.97
514_R589_F1.3420.97
71_K190_D1.3370.97
394_E397_A1.3340.97
503_E506_K1.3250.97
43_A206_L1.3220.97
87_R166_D1.3210.97
503_E507_A1.3140.97
361_E398_K1.3000.97
130_A178_L1.3000.97
49_R53_N1.2980.97
141_T152_V1.2960.97
405_T422_R1.2890.97
403_A438_Y1.2880.97
69_F76_L1.2880.97
151_G169_K1.2870.97
318_L357_L1.2830.96
107_E111_S1.2820.96
551_A566_Y1.2780.96
406_H424_K1.2780.96
104_S108_S1.2640.96
437_S440_A1.2600.96
262_T363_L1.2600.96
86_T146_E1.2470.96
575_V578_K1.2460.96
259_D282_S1.2370.96
314_M352_L1.2360.96
24_L334_V1.2310.96
258_N282_S1.2230.95
382_L396_I1.2180.95
331_P342_S1.2160.95
594_E617_R1.2130.95
140_R151_G1.2120.95
237_N240_E1.2100.95
248_E251_K1.2070.95
498_D502_K1.2040.95
360_L371_Y1.1980.95
26_S338_I1.1970.95
21_I30_I1.1960.95
87_R91_I1.1920.95
90_V139_V1.1910.95
141_T162_Y1.1830.94
238_K241_I1.1820.94
155_E165_A1.1720.94
262_T359_M1.1700.94
452_K533_T1.1680.94
59_G62_E1.1660.94
235_T275_T1.1640.94
587_A590_S1.1570.94
89_E93_H1.1550.94
266_N276_S1.1540.94
31_F133_V1.1460.93
69_F189_D1.1440.93
578_K582_D1.1420.93
46_L172_R1.1420.93
383_K465_D1.1380.93
570_L577_V1.1340.93
531_R540_S1.1340.93
439_A442_K1.1330.93
87_R152_V1.1320.93
107_E110_G1.1310.93
442_K451_R1.1280.93
514_R518_L1.1260.93
594_E613_L1.1250.93
389_D392_N1.1250.93
384_E388_E1.1210.93
375_W382_L1.1150.92
244_E247_K1.1150.92
448_E535_T1.1130.92
428_E479_P1.1090.92
248_E252_H1.1040.92
545_E549_Q1.0980.92
43_A81_N1.0970.92
46_L144_A1.0950.92
29_E199_K1.0940.92
297_L314_M1.0900.92
528_L572_P1.0870.91
76_L193_V1.0870.91
572_P575_V1.0860.91
420_V475_F1.0860.91
580_A592_W1.0820.91
591_E617_R1.0790.91
6_T161_E1.0710.91
595_L614_F1.0690.91
77_T177_T1.0660.91
7_R162_Y1.0660.91
246_Y279_Y1.0650.91
404_S422_R1.0570.90
233_L245_E1.0550.90
76_L180_L1.0440.90
428_E492_K1.0430.90
504_A573_D1.0410.90
93_H99_K1.0400.90
135_D157_A1.0380.89
614_F618_M1.0370.89
229_K252_H1.0300.89
594_E598_D1.0300.89
284_A377_Q1.0220.89
386_P400_L1.0120.88
615_I619_N1.0120.88
236_R240_E1.0110.88
356_V360_L1.0110.88
167_I170_E1.0080.88
35_L130_A1.0070.88
411_A442_K1.0040.88
280_I321_V1.0030.88
579_R582_D1.0030.88
231_Q236_R1.0030.88
64_R81_N1.0010.88
182_E185_D1.0010.88
442_K459_L0.9990.88
63_L81_N0.9930.87
319_R384_E0.9900.87
247_K251_K0.9870.87
428_E489_S0.9850.87
394_E476_D0.9850.87
153_F167_I0.9850.87
545_E548_T0.9820.87
87_R150_N0.9780.86
386_P468_M0.9770.86
68_S77_T0.9740.86
528_L570_L0.9720.86
546_M549_Q0.9690.86
63_L172_R0.9680.86
586_E590_S0.9660.86
245_E248_E0.9610.86
512_I528_L0.9590.85
49_R52_S0.9560.85
496_E499_E0.9500.85
210_I227_I0.9480.85
518_L590_S0.9450.85
79_S140_R0.9440.84
190_D195_S0.9400.84
305_F308_D0.9370.84
266_N355_R0.9360.84
578_K581_A0.9350.84
368_A401_R0.9350.84
37_S304_V0.9330.84
371_Y399_L0.9280.83
75_T179_H0.9260.83
597_L601_L0.9250.83
94_L164_V0.9240.83
302_Q327_S0.9210.83
524_K545_E0.9210.83
602_L608_L0.9180.83
92_D99_K0.9120.82
261_L363_L0.9110.82
20_M24_L0.9110.82
439_A443_S0.9090.82
18_H159_E0.9090.82
256_D283_Q0.9060.82
447_L459_L0.9060.82
524_K565_K0.9040.82
194_R210_I0.9040.82
71_K185_D0.9030.82
32_L76_L0.9010.82
516_K520_G0.9000.82
420_V423_M0.8990.81
191_W195_S0.8970.81
361_E395_A0.8960.81
371_Y375_W0.8920.81
68_S224_W0.8900.81
103_K107_E0.8890.81
549_Q553_L0.8890.81
372_Q401_R0.8830.80
91_I162_Y0.8830.80
241_I265_H0.8830.80
355_R358_Q0.8830.80
373_T377_Q0.8800.80
425_E454_G0.8800.80
531_R569_E0.8790.80
96_T99_K0.8760.80
263_W279_Y0.8750.80
102_T269_E0.8710.79
539_V597_L0.8700.79
350_N354_K0.8680.79
375_W379_G0.8680.79
146_E152_V0.8650.79
369_E372_Q0.8650.79
423_M427_Q0.8640.79
143_A146_E0.8630.79
534_D616_R0.8610.79
22_H181_R0.8610.79
267_R273_E0.8610.79
506_K513_D0.8610.79
316_N388_E0.8580.78
613_L617_R0.8550.78
508_L581_A0.8520.78
60_D81_N0.8450.77
452_K534_D0.8360.77
317_Y392_N0.8360.77
219_E222_I0.8340.76
260_P263_W0.8330.76
525_D567_I0.8320.76
211_E222_I0.8310.76
262_T280_I0.8300.76
497_V509_T0.8300.76
264_S359_M0.8280.76
542_D567_I0.8180.75
576_L622_L0.8170.75
406_H422_R0.8150.75
65_V208_V0.8130.74
122_Q125_V0.8130.74
79_S169_K0.8100.74
614_F617_R0.8100.74
447_L457_V0.8090.74
152_V166_D0.8080.74
585_D588_K0.8080.74
276_S352_L0.8080.74
441_A459_L0.8070.74
35_L134_A0.8060.74
466_E547_S0.8040.74
343_T347_N0.8030.74
307_M310_A0.8030.74
406_H451_R0.8010.73
402_F460_L0.8000.73
617_R620_Q0.7980.73
305_F614_F0.7970.73
70_D77_T0.7940.73
141_T180_L0.7940.73
189_D192_R0.7940.73
414_V458_L0.7920.73
94_L141_T0.7920.73
400_L468_M0.7900.72
416_L458_L0.7860.72
305_F314_M0.7850.72
7_R87_R0.7840.72
278_L356_V0.7840.72
297_L325_I0.7830.72
111_S115_K0.7830.72
507_A581_A0.7820.72
58_E61_G0.7810.71
505_E508_L0.7810.71
363_L367_D0.7790.71
583_T588_K0.7780.71
88_D363_L0.7780.71
9_F21_I0.7770.71
522_R609_E0.7760.71
525_D542_D0.7760.71
8_G161_E0.7730.71
151_G168_T0.7710.71
592_W621_L0.7700.70
522_R601_L0.7660.70
95_G162_Y0.7640.70
149_E168_T0.7620.70
410_S438_Y0.7610.70
261_L370_K0.7600.69
511_F582_D0.7600.69
545_E551_A0.7590.69
431_Y434_T0.7590.69
546_M553_L0.7570.69
504_A507_A0.7560.69
405_T615_I0.7560.69
375_W460_L0.7550.69
449_L488_E0.7550.69
298_K308_D0.7510.68
510_P513_D0.7510.68
317_Y389_D0.7510.68
257_F283_Q0.7490.68
317_Y538_I0.7490.68
269_E273_E0.7480.68
439_A609_E0.7480.68
460_L469_M0.7460.68
142_R170_E0.7450.68
520_G565_K0.7450.68
551_A555_A0.7440.68
583_T586_E0.7430.68
514_R586_E0.7420.68
599_Q614_F0.7420.68
294_K309_D0.7410.67
542_D546_M0.7400.67
354_K358_Q0.7400.67
153_F168_T0.7390.67
32_L193_V0.7390.67
550_M554_F0.7380.67
66_R211_E0.7380.67
153_F177_T0.7370.67
273_E328_S0.7370.67
438_Y461_S0.7360.67
302_Q345_T0.7350.67
7_R91_I0.7350.67
379_G383_K0.7320.67
56_L59_G0.7320.67
551_A564_V0.7310.66
72_D189_D0.7310.66
546_M554_F0.7300.66
18_H22_H0.7290.66
13_V24_L0.7280.66
527_R567_I0.7270.66
598_D601_L0.7270.66
498_D501_A0.7260.66
376_Q403_A0.7260.66
38_N41_D0.7250.66
278_L297_L0.7240.66
162_Y452_K0.7230.66
405_T414_V0.7220.65
450_L490_L0.7210.65
152_V164_V0.7200.65
532_L538_I0.7190.65
512_I516_K0.7170.65
358_Q395_A0.7170.65
511_F515_V0.7170.65
529_T532_L0.7150.65
32_L133_V0.7130.64
36_I67_V0.7130.64
510_P515_V0.7130.64
313_F325_I0.7120.64
194_R198_S0.7120.64
289_W468_M0.7110.64
618_M621_L0.7100.64
405_T451_R0.7090.64
142_R149_E0.7090.64
280_I356_V0.7080.64
114_A117_S0.7070.64
576_L592_W0.7070.64
20_M446_H0.7070.64
426_G429_K0.7070.64
48_F51_L0.7060.64
521_E565_K0.7060.64
508_L528_L0.7060.64
130_A134_A0.7030.63
73_K369_E0.7010.63
359_M362_K0.7010.63
109_L319_R0.6980.63
312_Q349_R0.6970.63
553_L556_A0.6970.63
161_E350_N0.6950.62
443_S616_R0.6950.62
317_Y371_Y0.6940.62
243_D259_D0.6900.62
187_F236_R0.6900.62
421_S424_K0.6870.62
80_D84_G0.6850.61
405_T447_L0.6850.61
452_K602_L0.6850.61
395_A398_K0.6840.61
69_F190_D0.6830.61
46_L277_L0.6820.61
514_R593_V0.6820.61
548_T551_A0.6810.61
424_K428_E0.6770.60
71_K92_D0.6770.60
372_Q376_Q0.6760.60
142_R167_I0.6750.60
58_E172_R0.6740.60
243_D370_K0.6740.60
542_D545_E0.6740.60
90_V176_I0.6740.60
568_F596_L0.6740.60
376_Q413_T0.6730.60
570_L575_V0.6720.60
431_Y435_A0.6720.60
151_G171_D0.6690.60
243_D582_D0.6690.60
501_A504_A0.6670.59
511_F577_V0.6670.59
282_S370_K0.6670.59
13_V160_G0.6660.59
30_I129_S0.6650.59
271_K347_N0.6650.59
549_Q557_A0.6630.59
70_D75_T0.6620.59
155_E590_S0.6610.59
524_K567_I0.6610.59
103_K480_F0.6590.58
513_D516_K0.6590.58
57_Y62_E0.6590.58
45_K105_F0.6580.58
185_D188_L0.6580.58
341_D346_R0.6580.58
142_R151_G0.6580.58
122_Q302_Q0.6570.58
249_F404_S0.6570.58
110_G114_A0.6560.58
387_A471_Y0.6550.58
427_Q455_I0.6550.58
511_F581_A0.6550.58
162_Y511_F0.6550.58
68_S175_E0.6540.58
579_R592_W0.6530.58
34_E38_N0.6530.58
591_E594_E0.6520.58
190_D211_E0.6520.58
46_L56_L0.6520.58
36_I306_I0.6510.57
8_G14_K0.6510.57
612_N616_R0.6500.57
94_L297_L0.6500.57
496_E505_E0.6500.57
361_E365_K0.6490.57
145_G149_E0.6490.57
272_Q347_N0.6480.57
551_A563_E0.6480.57
288_M291_R0.6480.57
515_V518_L0.6470.57
284_A288_M0.6470.57
197_I512_I0.6470.57
414_V421_S0.6460.57
42_A174_T0.6460.57
387_A467_W0.6460.57
366_D369_E0.6460.57
422_R459_L0.6450.57
11_S338_I0.6450.57
314_M353_T0.6450.57
481_Q543_A0.6440.57
33_R41_D0.6430.57
62_E207_P0.6430.57
87_R141_T0.6420.56
49_R54_P0.6420.56
545_E552_K0.6410.56
233_L519_L0.6400.56
424_K455_I0.6400.56
20_M363_L0.6400.56
150_N168_T0.6390.56
28_K40_S0.6390.56
33_R38_N0.6380.56
278_L323_G0.6380.56
541_T551_A0.6380.56
449_L453_K0.6370.56
78_I178_L0.6360.56
49_R83_V0.6360.56
587_A620_Q0.6350.56
74_R183_G0.6340.55
390_F393_Q0.6340.55
17_L20_M0.6330.55
270_G308_D0.6320.55
507_A510_P0.6320.55
301_V306_I0.6320.55
614_F622_L0.6310.55
141_T153_F0.6310.55
251_K256_D0.6300.55
18_H21_I0.6300.55
149_E152_V0.6290.55
195_S199_K0.6290.55
548_T552_K0.6290.55
50_A63_L0.6280.55
136_K294_K0.6270.55
403_A410_S0.6270.55
550_M553_L0.6260.55
381_V384_E0.6260.55
261_L377_Q0.6260.55
393_Q471_Y0.6250.54
341_D344_V0.6250.54
92_D141_T0.6230.54
193_V227_I0.6220.54
26_S467_W0.6220.54
261_L373_T0.6220.54
269_E277_L0.6200.54
86_T282_S0.6200.54
232_A254_A0.6190.54
364_A368_A0.6180.54
549_Q555_A0.6180.54
140_R168_T0.6170.53
512_I525_D0.6170.53
502_K613_L0.6140.53
426_G492_K0.6140.53
13_V102_T0.6140.53
501_A530_H0.6120.53
263_W277_L0.6120.53
419_Y423_M0.6110.53
357_L382_L0.6110.53
199_K346_R0.6100.53
485_K542_D0.6100.53
324_L614_F0.6070.52
202_D252_H0.6070.52
29_E399_L0.6060.52
439_A515_V0.6050.52
357_L396_I0.6040.52
139_V164_V0.6030.52
393_Q511_F0.6020.52
76_L189_D0.6020.52
416_L480_F0.6020.52
245_E256_D0.6010.52
393_Q397_A0.6010.52
352_L377_Q0.6010.52
203_H230_A0.6000.51
102_T301_V0.6000.51
53_N56_L0.6000.51
60_D172_R0.6000.51
288_M381_V0.5980.51
351_A355_R0.5970.51
527_R569_E0.5970.51
27_N341_D0.5960.51
9_F12_E0.5950.51
589_F592_W0.5950.51
193_V208_V0.5940.51
242_T471_Y0.5930.51
440_A480_F0.5920.51
15_Q19_L0.5910.50
158_G274_Y0.5900.50
65_V404_S0.5900.50
416_L424_K0.5900.50
573_D578_K0.5900.50
554_F558_G0.5890.50
65_V88_D0.5890.50
106_L576_L0.5880.50
245_E276_S0.5880.50
180_L197_I0.5880.50
372_Q413_T0.5880.50
85_M90_V0.5870.50
515_V526_V0.5860.50
323_G340_Q0.5850.50
94_L355_R0.5850.50
358_Q361_E0.5850.50
50_A57_Y0.5840.50
9_F320_F0.5840.50
289_W381_V0.5840.50
438_Y451_R0.5830.49
83_V352_L0.5820.49
134_A211_E0.5820.49
57_Y172_R0.5820.49
447_L450_L0.5810.49
456_E459_L0.5800.49
65_V474_E0.5800.49
138_T167_I0.5800.49
306_I332_L0.5800.49
186_E189_D0.5800.49
163_T534_D0.5780.49
89_E149_E0.5780.49
201_S204_I0.5770.49
12_E16_L0.5770.49
143_A172_R0.5770.49
360_L399_L0.5760.49
72_D221_V0.5760.49
448_E452_K0.5750.49
487_D529_T0.5750.49
347_N351_A0.5740.48
434_T460_L0.5740.48
249_F324_L0.5740.48
361_E364_A0.5720.48
30_I239_S0.5720.48
74_R188_L0.5720.48
68_S76_L0.5720.48
242_T279_Y0.5710.48
156_S162_Y0.5710.48
20_M384_E0.5690.48
187_F192_R0.5680.48
260_P326_D0.5670.48
404_S504_A0.5660.47
548_T566_Y0.5650.47
14_K159_E0.5650.47
313_F555_A0.5630.47
176_I366_D0.5630.47
279_Y396_I0.5630.47
176_I544_D0.5620.47
592_W622_L0.5610.47
34_E41_D0.5610.47
99_K297_L0.5600.47
267_R276_S0.5590.47
404_S413_T0.5590.47
595_L598_D0.5590.47
448_E534_D0.5590.47
459_L483_V0.5590.47
296_G404_S0.5580.46
89_E577_V0.5580.46
468_M471_Y0.5570.46
485_K544_D0.5570.46
236_R311_E0.5560.46
500_S504_A0.5560.46
141_T515_V0.5550.46
536_P539_V0.5550.46
60_D208_V0.5550.46
444_S598_D0.5550.46
253_I257_F0.5540.46
434_T466_E0.5540.46
479_P505_E0.5540.46
350_N478_K0.5530.46
300_Y327_S0.5530.46
30_I125_V0.5530.46
601_L606_G0.5530.46
5_E421_S0.5520.46
325_I345_T0.5520.46
326_D385_G0.5520.46
267_R271_K0.5520.46
371_Y415_S0.5510.46
497_V500_S0.5510.46
434_T439_A0.5510.46
584_E594_E0.5510.46
241_I248_E0.5500.46
421_S476_D0.5500.46
428_E478_K0.5500.46
181_R184_E0.5500.46
394_E474_E0.5500.46
444_S448_E0.5500.46
447_L482_S0.5490.45
88_D91_I0.5490.45
280_I425_E0.5480.45
531_R538_I0.5480.45
202_D229_K0.5470.45
111_S114_A0.5470.45
152_V167_I0.5470.45
23_S201_S0.5460.45
56_L144_A0.5450.45
73_K77_T0.5450.45
406_H456_E0.5450.45
140_R170_E0.5440.45
27_N339_L0.5430.45
218_G417_E0.5430.45
182_E358_Q0.5430.45
532_L535_T0.5420.45
27_N342_S0.5420.45
411_A505_E0.5420.45
241_I263_W0.5420.45
166_D170_E0.5420.45
357_L361_E0.5410.44
507_A578_K0.5390.44
531_R535_T0.5380.44
81_N171_D0.5380.44
517_A590_S0.5380.44
33_R336_R0.5380.44
202_D248_E0.5380.44
233_L327_S0.5370.44
599_Q615_I0.5370.44
55_D58_E0.5370.44
507_A575_V0.5360.44
111_S240_E0.5350.44
172_R539_V0.5350.44
428_E477_G0.5340.44
547_S551_A0.5340.44
282_S377_Q0.5340.44
297_L348_L0.5320.43
167_I171_D0.5320.43
619_N622_L0.5310.43
364_A372_Q0.5310.43
99_K345_T0.5300.43
547_S550_M0.5300.43
534_D586_E0.5300.43
421_S456_E0.5290.43
247_K258_N0.5290.43
19_L24_L0.5290.43
546_M551_A0.5280.43
196_I224_W0.5270.43
378_F490_L0.5270.43
436_D441_A0.5270.43
15_Q18_H0.5270.43
435_A440_A0.5260.43
129_S386_P0.5260.43
225_E402_F0.5260.43
103_K302_Q0.5260.43
332_L385_G0.5260.43
211_E220_T0.5250.43
403_A412_Q0.5250.43
197_I210_I0.5250.43
613_L616_R0.5250.43
132_I359_M0.5240.43
535_T538_I0.5240.43
26_S337_E0.5240.43
221_V224_W0.5240.43
258_N327_S0.5230.42
162_Y358_Q0.5230.42
51_L396_I0.5230.42
402_F414_V0.5220.42
427_Q431_Y0.5220.42
246_Y250_Y0.5220.42
262_T370_K0.5210.42
392_N395_A0.5210.42
54_P57_Y0.5200.42
223_S353_T0.5200.42
290_N316_N0.5200.42
406_H414_V0.5200.42
108_S161_E0.5200.42
252_H255_H0.5200.42
181_R505_E0.5200.42
248_E539_V0.5200.42
566_Y605_R0.5200.42
420_V428_E0.5200.42
57_Y63_L0.5190.42
429_K455_I0.5190.42
593_V597_L0.5190.42
157_A161_E0.5190.42
103_K264_S0.5190.42
83_V186_E0.5180.42
27_N317_Y0.5180.42
326_D332_L0.5170.42
182_E447_L0.5170.42
17_L385_G0.5160.42
198_S229_K0.5160.42
15_Q94_L0.5160.42
266_N352_L0.5160.42
363_L370_K0.5160.42
300_Y304_V0.5150.41
555_A560_K0.5150.41
599_Q602_L0.5150.41
599_Q603_A0.5150.41
26_S339_L0.5140.41
450_L455_I0.5140.41
56_L145_G0.5140.41
394_E475_F0.5140.41
161_E181_R0.5140.41
501_A505_E0.5130.41
6_T157_A0.5130.41
309_D312_Q0.5130.41
382_L399_L0.5130.41
36_I51_L0.5120.41
162_Y401_R0.5110.41
398_K420_V0.5110.41
67_V570_L0.5100.41
307_M450_L0.5100.41
51_L54_P0.5100.41
295_H316_N0.5100.41
451_R454_G0.5100.41
205_A549_Q0.5090.41
603_A611_P0.5090.41
304_V574_H0.5090.41
292_D311_E0.5090.41
64_R171_D0.5080.41
49_R145_G0.5080.41
541_T552_K0.5070.41
394_E398_K0.5070.41
55_D594_E0.5070.41
242_T622_L0.5060.40
111_S116_D0.5060.40
40_S228_N0.5060.40
432_Y480_F0.5060.40
131_F193_V0.5060.40
233_L277_L0.5050.40
220_T223_S0.5050.40
240_E245_E0.5050.40
430_I475_F0.5050.40
44_D97_I0.5040.40
272_Q351_A0.5040.40
386_P389_D0.5030.40
13_V119_L0.5030.40
536_P540_S0.5030.40
514_R590_S0.5030.40
141_T224_W0.5030.40
131_F310_A0.5020.40
118_Q601_L0.5020.40
252_H257_F0.5020.40
334_V338_I0.5020.40
196_I203_H0.5010.40
25_Y38_N0.5010.40
546_M552_K0.5010.40
228_N234_W0.5000.40
62_E394_E0.5000.40
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2cg9A 2 0.9663 100 0.151 Contact Map
2ioqA 2 0.9455 100 0.173 Contact Map
2o1uA 2 0.891 100 0.186 Contact Map
4ivgA 4 0.7388 100 0.219 Contact Map
4ipeA 2 0.9503 100 0.224 Contact Map
1y4sA 2 0.7612 100 0.25 Contact Map
3hjcA 5 0.6058 100 0.43 Contact Map
3q6mA 4 0.5865 100 0.431 Contact Map
2cgeA 6 0.625 100 0.439 Contact Map
2gq0A 1 0.4247 100 0.563 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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