HSCA - ECOLI - GREMLIN Contacts

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HSCA - Chaperone protein HscA

UniProt:	P0A6Z1	Sequences: MALLQISEPGLSAAPHQRRLAAGIDLGTTNSLVATVRSGQAETLADHEGRHLLPSVVHYQQQGHSVGYDARTNAALDTANTISSVKRLMGRSLADIQQRYPHLPYQFQASENGLPMIETAAGLLNPVRVSADILKALAARATEALAGELDGVVITVPAYFDDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYGLDSGQEGVIAVYDLGGGTFDISILRLSRGVFEVLATGGDSALGGDDFDHLLADYIREQAGIPDRSDNRVQRELLDAAIAAKIALSDADSVTVNVAGWQGEISREQFNELIAPLVKRTLLACRRALKDAGVEADEVLEVVMVGGSTRVPLVRERVGEFFGRPPLTSIDPDKVVAIGAAIQADILVGNKPDSEMLLLDVIPLSLGLETMGGLVEKVIPRNTTIPVARAQDFTTFKDGQTAMSIHVMQGERELVQDCRSLARFALRGIPALPAGGAHIRVTFQVDADGLLSVTAMEKSTGVEASIQVKPSYGLTDSEIASMIKDSMSYAEQDVKARMLAEQKVEAARVLESLHGALAADAALLSAAERQVIDDAAAHLSEVAQGDDVDAIEQAIKNVDKQTQDFAARRMDQSVRRALKGHSVDEV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12130
Length:	616 (578)
Sequences:	6671 (3254)
Seq/√Len:	135.3

ECOLI - HSCA DNAK HSCC
BACSU - DNAK
HALSA - DNAK

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
151_G	178_H	5.319	1.00
233_D	310_R	4.830	1.00
244_L	306_P	4.709	1.00
245_L	295_I	3.732	1.00
349_G	355_P	3.635	1.00
206_Y	311_T	3.631	1.00
283_S	294_E	3.440	1.00
346_E	350_E	3.409	1.00
252_Q	299_Q	3.266	1.00
84_S	239_D	3.246	1.00
217_I	318_A	3.195	1.00
46_D	53_L	2.954	1.00
544_H	570_S	2.909	1.00
50_R	68_Y	2.902	1.00
506_D	510_A	2.883	1.00
395_S	407_K	2.867	1.00
406_E	423_F	2.803	1.00
118_E	123_L	2.779	1.00
434_S	455_A	2.746	1.00
436_H	450_S	2.722	1.00
577_D	580_A	2.720	1.00
250_R	258_R	2.689	1.00
361_D	364_K	2.641	1.00
249_I	293_G	2.564	1.00
151_G	180_L	2.542	1.00
407_K	410_P	2.541	1.00
229_A	318_A	2.494	1.00
519_Y	522_Q	2.454	1.00
345_R	358_T	2.423	1.00
118_E	121_A	2.419	1.00
299_Q	302_E	2.383	1.00
106_Q	118_E	2.296	1.00
208_L	241_F	2.289	1.00
560_Q	564_D	2.280	1.00
249_I	271_A	2.255	1.00
305_A	309_K	2.237	1.00
21_A	180_L	2.235	1.00
517_M	520_A	2.229	1.00
582_E	586_K	2.226	1.00
138_A	142_T	2.209	1.00
204_A	217_I	2.175	1.00
567_A	571_E	2.146	1.00
486_M	493_E	2.117	1.00
338_S	341_V	2.111	1.00
204_A	215_I	2.103	1.00
511_S	515_D	2.092	1.00
304_I	341_V	2.082	1.00
551_A	559_R	2.079	1.00
312_L	351_F	2.073	1.00
397_G	405_V	2.071	1.00
85_V	117_I	2.069	1.00
79_A	106_Q	2.061	1.00
308_V	343_L	2.041	1.00
555_S	558_E	2.011	1.00
438_M	450_S	2.010	1.00
521_E	525_K	2.009	1.00
241_F	307_L	1.991	1.00
563_D	567_A	1.967	1.00
285_T	292_Q	1.959	1.00
347_R	350_E	1.947	1.00
571_E	574_Q	1.931	1.00
524_V	528_M	1.917	1.00
243_H	247_D	1.914	1.00
139_A	143_E	1.910	1.00
580_A	584_A	1.897	1.00
313_L	317_R	1.889	1.00
536_A	569_L	1.885	1.00
514_K	518_S	1.884	1.00
124_L	129_V	1.875	1.00
22_A	33_V	1.870	1.00
37_R	42_E	1.868	1.00
586_K	590_K	1.861	1.00
578_V	582_E	1.857	1.00
246_A	268_L	1.855	1.00
558_E	598_R	1.846	1.00
34_A	371_A	1.842	1.00
594_D	597_A	1.837	1.00
155_T	370_A	1.833	1.00
166_Q	170_D	1.793	1.00
300_F	341_V	1.790	1.00
301_N	346_E	1.787	1.00
340_R	363_D	1.775	1.00
21_A	374_A	1.748	1.00
296_S	299_Q	1.746	1.00
316_R	351_F	1.743	1.00
201_G	331_E	1.723	1.00
272_I	276_I	1.710	1.00
173_R	178_H	1.710	1.00
592_T	596_A	1.705	1.00
79_A	261_N	1.703	1.00
132_D	135_K	1.687	1.00
434_S	453_R	1.677	1.00
31_S	137_L	1.671	1.00
556_A	560_Q	1.669	1.00
325_E	328_E	1.666	1.00
543_L	592_T	1.665	1.00
514_K	517_M	1.657	1.00
313_L	316_R	1.627	1.00
32_L	52_L	1.627	1.00
312_L	316_R	1.609	1.00
436_H	453_R	1.604	1.00
80_N	120_A	1.594	1.00
400_T	406_E	1.592	1.00
217_I	329_V	1.592	1.00
510_A	514_K	1.590	1.00
270_A	274_A	1.589	1.00
274_A	284_V	1.586	1.00
97_Q	100_Y	1.570	1.00
584_A	587_N	1.566	1.00
51_H	364_K	1.561	1.00
589_D	593_Q	1.561	1.00
564_D	568_H	1.560	1.00
94_A	113_G	1.556	1.00
136_A	140_R	1.550	1.00
300_F	338_S	1.534	1.00
594_D	598_R	1.534	1.00
32_L	43_T	1.524	1.00
127_V	170_D	1.510	1.00
304_I	308_V	1.510	1.00
420_A	470_R	1.505	1.00
302_E	305_A	1.503	1.00
559_R	563_D	1.501	1.00
420_A	472_T	1.499	1.00
249_I	286_V	1.494	1.00
540_L	570_S	1.490	1.00
44_L	144_A	1.487	1.00
565_A	568_H	1.486	1.00
316_R	320_K	1.480	1.00
389_L	414_T	1.476	1.00
173_R	506_D	1.475	1.00
581_I	588_V	1.471	1.00
444_L	447_D	1.466	1.00
59_Y	132_D	1.465	1.00
245_L	271_A	1.454	1.00
331_E	357_L	1.449	1.00
244_L	304_I	1.441	1.00
202_V	219_R	1.440	1.00
584_A	588_V	1.439	1.00
299_Q	303_L	1.433	1.00
568_H	584_A	1.432	1.00
208_L	213_F	1.426	1.00
249_I	267_L	1.419	1.00
248_Y	303_L	1.415	1.00
170_D	173_R	1.412	1.00
444_L	530_A	1.402	1.00
248_Y	299_Q	1.401	1.00
130_S	168_T	1.399	1.00
58_H	73_N	1.395	1.00
407_K	443_E	1.394	1.00
515_D	518_S	1.393	1.00
33_V	137_L	1.391	1.00
88_L	117_I	1.379	1.00
83_S	104_P	1.379	1.00
77_D	80_N	1.379	1.00
312_L	347_R	1.376	1.00
274_A	286_V	1.376	1.00
34_A	367_A	1.370	1.00
468_H	488_K	1.364	1.00
110_S	113_G	1.363	1.00
317_R	321_D	1.362	1.00
585_I	589_D	1.348	1.00
154_I	172_A	1.347	1.00
565_A	569_L	1.346	1.00
399_E	436_H	1.342	1.00
85_V	133_I	1.341	1.00
505_T	508_E	1.339	1.00
450_S	453_R	1.338	1.00
137_L	140_R	1.338	1.00
406_E	421_Q	1.329	1.00
172_A	182_L	1.324	1.00
570_S	574_Q	1.324	1.00
558_E	561_V	1.321	1.00
43_T	368_I	1.320	1.00
319_L	326_A	1.317	1.00
26_L	168_T	1.314	1.00
82_I	119_T	1.311	1.00
248_Y	252_Q	1.310	1.00
508_E	511_S	1.309	1.00
535_E	585_I	1.306	1.00
413_T	417_V	1.292	1.00
85_V	130_S	1.291	1.00
593_Q	597_A	1.289	1.00
586_K	589_D	1.288	1.00
583_Q	587_N	1.283	1.00
85_V	129_V	1.282	1.00
422_D	470_R	1.277	1.00
346_E	349_G	1.276	1.00
520_A	524_V	1.274	1.00
540_L	566_A	1.271	1.00
392_I	475_V	1.271	1.00
247_D	258_R	1.270	1.00
252_Q	293_G	1.269	1.00
73_N	77_D	1.269	1.00
577_D	588_V	1.267	1.00
565_A	591_Q	1.266	1.00
593_Q	596_A	1.266	1.00
36_V	375_D	1.266	1.00
111_E	116_M	1.261	1.00
217_I	324_V	1.260	1.00
556_A	563_D	1.256	1.00
581_I	584_A	1.250	1.00
82_I	129_V	1.246	1.00
26_L	134_L	1.233	1.00
587_N	591_Q	1.228	1.00
274_A	295_I	1.224	1.00
565_A	587_N	1.220	1.00
317_R	320_K	1.218	1.00
308_V	347_R	1.216	1.00
57_V	129_V	1.212	1.00
138_A	177_L	1.210	1.00
241_F	300_F	1.209	1.00
202_V	324_V	1.209	1.00
521_E	524_V	1.208	1.00
297_R	301_N	1.206	1.00
534_V	541_E	1.201	1.00
47_H	140_R	1.198	1.00
544_H	548_A	1.198	1.00
41_A	368_I	1.194	1.00
231_G	314_A	1.193	1.00
540_L	569_L	1.191	1.00
128_R	132_D	1.186	0.99
527_R	531_E	1.185	0.99
532_Q	585_I	1.184	0.99
93_L	97_Q	1.184	0.99
247_D	251_E	1.174	0.99
204_A	315_C	1.173	0.99
432_A	455_A	1.167	0.99
270_A	273_A	1.167	0.99
251_E	258_R	1.166	0.99
59_Y	119_T	1.159	0.99
588_V	598_R	1.157	0.99
590_K	593_Q	1.154	0.99
56_V	83_S	1.154	0.99
108_Q	118_E	1.153	0.99
246_A	271_A	1.153	0.99
248_Y	293_G	1.152	0.99
228_L	324_V	1.152	0.99
529_L	576_D	1.148	0.99
588_V	592_T	1.141	0.99
131_A	174_L	1.141	0.99
241_F	304_I	1.133	0.99
348_V	356_P	1.132	0.99
578_V	581_I	1.131	0.99
241_F	341_V	1.128	0.99
31_S	55_S	1.124	0.99
184_N	187_T	1.123	0.99
169_K	480_L	1.123	0.99
405_V	438_M	1.116	0.99
579_D	583_Q	1.115	0.99
231_G	317_R	1.115	0.99
28_T	211_G	1.112	0.99
305_A	343_L	1.110	0.99
577_D	581_I	1.106	0.99
59_Y	124_L	1.104	0.99
219_R	228_L	1.101	0.99
592_T	598_R	1.101	0.99
100_Y	107_F	1.094	0.99
180_L	377_L	1.094	0.99
438_M	445_V	1.092	0.99
321_D	411_R	1.091	0.99
86_K	185_E	1.090	0.99
561_V	591_Q	1.090	0.99
29_T	210_G	1.088	0.99
589_D	592_T	1.085	0.99
561_V	594_D	1.085	0.99
277_A	284_V	1.083	0.99
418_A	472_T	1.081	0.99
45_A	51_H	1.079	0.99
252_Q	255_I	1.077	0.99
343_L	346_E	1.075	0.99
36_V	41_A	1.070	0.99
547_L	559_R	1.068	0.99
532_Q	582_E	1.067	0.99
172_A	179_V	1.064	0.99
89_M	168_T	1.062	0.99
596_A	599_R	1.061	0.99
87_R	240_D	1.056	0.99
568_H	587_N	1.054	0.99
542_S	546_A	1.054	0.99
97_Q	101_P	1.050	0.99
20_L	147_G	1.048	0.99
26_L	130_S	1.047	0.99
244_L	247_D	1.042	0.99
61_Q	120_A	1.042	0.99
243_H	268_L	1.037	0.99
432_A	457_R	1.036	0.99
522_Q	525_K	1.030	0.99
550_D	599_R	1.029	0.99
184_N	390_D	1.025	0.98
250_R	267_L	1.025	0.98
579_D	582_E	1.024	0.98
248_Y	295_I	1.019	0.98
583_Q	586_K	1.019	0.98
202_V	228_L	1.018	0.98
557_A	561_V	1.015	0.98
82_I	85_V	1.015	0.98
287_N	292_Q	1.014	0.98
422_D	488_K	1.014	0.98
428_D	464_A	1.013	0.98
22_A	152_V	1.012	0.98
213_F	311_T	1.011	0.98
165_R	184_N	1.010	0.98
161_D	164_Q	1.009	0.98
324_V	328_E	1.008	0.98
575_G	580_A	1.008	0.98
186_P	214_D	1.008	0.98
343_L	347_R	1.006	0.98
162_D	166_Q	0.998	0.98
319_L	324_V	0.997	0.98
142_T	148_E	0.995	0.98
560_Q	563_D	0.985	0.98
561_V	565_A	0.984	0.98
116_M	125_N	0.983	0.98
135_K	139_A	0.980	0.98
572_V	584_A	0.978	0.98
512_M	515_D	0.975	0.98
418_A	474_Q	0.972	0.98
561_V	564_D	0.971	0.98
252_Q	291_W	0.969	0.98
318_A	322_A	0.966	0.98
580_A	583_Q	0.964	0.98
460_P	489_S	0.963	0.98
537_A	541_E	0.962	0.98
260_D	263_V	0.961	0.98
124_L	132_D	0.958	0.98
539_V	543_L	0.958	0.98
581_I	592_T	0.955	0.98
315_C	351_F	0.955	0.98
528_M	582_E	0.952	0.98
316_R	326_A	0.949	0.98
588_V	591_Q	0.947	0.97
270_A	284_V	0.947	0.97
266_E	270_A	0.946	0.97
533_K	573_A	0.945	0.97
399_E	403_G	0.945	0.97
590_K	594_D	0.944	0.97
564_D	567_A	0.944	0.97
577_D	598_R	0.942	0.97
43_T	51_H	0.939	0.97
249_I	295_I	0.938	0.97
568_H	572_V	0.938	0.97
241_F	308_V	0.938	0.97
428_D	465_G	0.937	0.97
395_S	441_E	0.936	0.97
577_D	584_A	0.935	0.97
34_A	43_T	0.935	0.97
544_H	566_A	0.935	0.97
309_K	347_R	0.934	0.97
581_I	585_I	0.933	0.97
45_A	144_A	0.929	0.97
304_I	307_L	0.929	0.97
581_I	598_R	0.924	0.97
591_Q	594_D	0.924	0.97
571_E	575_G	0.923	0.97
547_L	566_A	0.922	0.97
317_R	411_R	0.922	0.97
108_Q	123_L	0.921	0.97
286_V	295_I	0.920	0.97
543_L	562_I	0.917	0.97
585_I	588_V	0.917	0.97
349_G	356_P	0.912	0.97
314_A	318_A	0.908	0.97
584_A	589_D	0.906	0.97
100_Y	106_Q	0.903	0.97
215_I	318_A	0.900	0.97
476_D	482_S	0.899	0.97
243_H	246_A	0.895	0.96
532_Q	535_E	0.893	0.96
110_S	116_M	0.893	0.96
249_I	291_W	0.890	0.96
572_V	575_G	0.889	0.96
270_A	277_A	0.885	0.96
562_I	591_Q	0.884	0.96
154_I	179_V	0.883	0.96
60_Q	63_G	0.879	0.96
245_L	248_Y	0.879	0.96
304_I	343_L	0.879	0.96
554_L	559_R	0.876	0.96
229_A	322_A	0.873	0.96
539_V	585_I	0.873	0.96
244_L	307_L	0.871	0.96
531_E	535_E	0.870	0.96
557_A	560_Q	0.869	0.96
543_L	566_A	0.868	0.96
218_L	227_V	0.867	0.96
572_V	576_D	0.865	0.96
547_L	563_D	0.865	0.96
572_V	580_A	0.863	0.96
185_E	214_D	0.862	0.96
452_A	498_V	0.859	0.96
295_I	300_F	0.856	0.95
98_Q	102_H	0.855	0.95
285_T	294_E	0.853	0.95
463_P	466_G	0.853	0.95
253_A	291_W	0.851	0.95
545_G	549_A	0.849	0.95
584_A	598_R	0.839	0.95
581_I	589_D	0.837	0.95
373_Q	376_I	0.836	0.95
562_I	592_T	0.836	0.95
462_L	487_E	0.836	0.95
593_Q	600_M	0.836	0.95
77_D	81_T	0.834	0.95
35_T	145_L	0.834	0.95
208_L	307_L	0.831	0.95
401_M	426_F	0.830	0.95
462_L	467_A	0.829	0.95
489_S	600_M	0.828	0.95
202_V	330_L	0.827	0.95
425_T	430_Q	0.827	0.95
204_A	352_F	0.823	0.94
596_A	600_M	0.822	0.94
529_L	532_Q	0.822	0.94
21_A	151_G	0.821	0.94
116_M	123_L	0.819	0.94
592_T	599_R	0.816	0.94
528_M	578_V	0.816	0.94
246_A	264_Q	0.815	0.94
533_K	576_D	0.815	0.94
51_H	361_D	0.812	0.94
535_E	589_D	0.811	0.94
158_A	186_P	0.811	0.94
301_N	343_L	0.808	0.94
58_H	77_D	0.808	0.94
315_C	348_V	0.807	0.94
173_R	513_I	0.806	0.94
550_D	554_L	0.805	0.94
139_A	142_T	0.804	0.94
312_L	315_C	0.802	0.94
556_A	559_R	0.802	0.94
584_A	591_Q	0.802	0.94
546_A	550_D	0.800	0.93
534_V	538_R	0.800	0.93
569_L	581_I	0.798	0.93
589_D	596_A	0.796	0.93
474_Q	482_S	0.796	0.93
231_G	321_D	0.796	0.93
584_A	594_D	0.796	0.93
569_L	584_A	0.788	0.93
555_S	598_R	0.788	0.93
529_L	533_K	0.787	0.93
56_V	71_R	0.787	0.93
425_T	465_G	0.786	0.93
540_L	573_A	0.786	0.93
554_L	558_E	0.783	0.93
89_M	130_S	0.783	0.93
140_R	143_E	0.783	0.93
510_A	513_I	0.780	0.93
458_G	462_L	0.780	0.93
433_M	469_I	0.779	0.93
250_R	264_Q	0.777	0.92
22_A	141_A	0.777	0.92
158_A	214_D	0.777	0.92
98_Q	101_P	0.775	0.92
357_L	365_V	0.770	0.92
470_R	486_M	0.769	0.92
156_V	182_L	0.765	0.92
560_Q	571_E	0.765	0.92
99_R	235_A	0.764	0.92
211_G	214_D	0.764	0.92
85_V	89_M	0.763	0.92
46_D	140_R	0.759	0.92
25_D	28_T	0.759	0.92
58_H	65_S	0.757	0.91
422_D	468_H	0.757	0.91
560_Q	568_H	0.756	0.91
539_V	589_D	0.755	0.91
86_K	211_G	0.755	0.91
60_Q	64_H	0.754	0.91
251_E	254_G	0.753	0.91
504_L	512_M	0.751	0.91
315_C	352_F	0.749	0.91
201_G	330_L	0.749	0.91
567_A	574_Q	0.747	0.91
181_R	373_Q	0.747	0.91
575_G	581_I	0.746	0.91
592_T	595_F	0.746	0.91
122_G	128_R	0.744	0.91
578_V	592_T	0.744	0.91
80_N	119_T	0.741	0.91
34_A	41_A	0.741	0.91
171_A	175_A	0.740	0.91
266_E	288_V	0.740	0.91
589_D	598_R	0.739	0.90
22_A	149_L	0.738	0.90
217_I	322_A	0.738	0.90
471_V	483_V	0.737	0.90
578_V	588_V	0.737	0.90
91_R	95_D	0.736	0.90
595_F	598_R	0.735	0.90
548_A	551_A	0.735	0.90
529_L	573_A	0.734	0.90
425_T	428_D	0.734	0.90
443_E	527_R	0.734	0.90
257_D	263_V	0.732	0.90
88_L	93_L	0.732	0.90
537_A	570_S	0.729	0.90
530_A	533_K	0.728	0.90
53_L	140_R	0.725	0.90
319_L	329_V	0.725	0.90
525_K	528_M	0.723	0.90
424_T	467_A	0.722	0.89
566_A	570_S	0.721	0.89
532_Q	578_V	0.721	0.89
180_L	374_A	0.720	0.89
136_A	139_A	0.716	0.89
537_A	573_A	0.716	0.89
258_R	264_Q	0.715	0.89
535_E	540_L	0.714	0.89
580_A	598_R	0.714	0.89
330_L	354_R	0.713	0.89
375_D	381_K	0.713	0.89
577_D	585_I	0.711	0.89
545_G	548_A	0.710	0.89
156_V	165_R	0.709	0.89
154_I	168_T	0.708	0.89
387_L	477_A	0.707	0.88
556_A	567_A	0.707	0.88
93_L	100_Y	0.706	0.88
592_T	597_A	0.704	0.88
21_A	378_V	0.703	0.88
584_A	592_T	0.703	0.88
587_N	590_K	0.703	0.88
582_E	587_N	0.701	0.88
462_L	466_G	0.700	0.88
536_A	585_I	0.700	0.88
347_R	351_F	0.700	0.88
156_V	184_N	0.698	0.88
442_R	523_D	0.698	0.88
186_P	212_T	0.697	0.88
134_L	168_T	0.697	0.88
593_Q	598_R	0.696	0.88
470_R	488_K	0.693	0.87
110_S	114_L	0.692	0.87
581_I	591_Q	0.691	0.87
525_K	579_D	0.689	0.87
224_V	387_L	0.689	0.87
581_I	594_D	0.685	0.87
437_V	473_F	0.684	0.87
26_L	363_D	0.683	0.87
221_S	224_V	0.683	0.87
326_A	351_F	0.681	0.87
111_E	123_L	0.681	0.87
309_K	312_L	0.679	0.86
114_L	127_V	0.679	0.86
198_G	201_G	0.678	0.86
273_A	277_A	0.678	0.86
61_Q	64_H	0.677	0.86
202_V	329_V	0.676	0.86
553_L	558_E	0.675	0.86
213_F	236_L	0.675	0.86
577_D	589_D	0.674	0.86
582_E	590_K	0.673	0.86
233_D	236_L	0.672	0.86
88_L	91_R	0.671	0.86
548_A	563_D	0.670	0.86
155_T	366_V	0.669	0.86
46_D	51_H	0.669	0.86
572_V	581_I	0.668	0.85
301_N	341_V	0.667	0.85
424_T	468_H	0.667	0.85
59_Y	129_V	0.666	0.85
47_H	136_A	0.666	0.85
377_L	477_A	0.666	0.85
440_G	448_C	0.664	0.85
528_M	531_E	0.663	0.85
400_T	423_F	0.663	0.85
334_M	348_V	0.663	0.85
246_A	267_L	0.661	0.85
127_V	167_G	0.660	0.85
89_M	167_G	0.659	0.85
533_K	537_A	0.658	0.85
532_Q	541_E	0.658	0.85
279_S	342_P	0.658	0.85
135_K	138_A	0.656	0.84
24_I	152_V	0.656	0.84
191_I	386_M	0.653	0.84
399_E	438_M	0.653	0.84
595_F	600_M	0.652	0.84
567_A	570_S	0.651	0.84
518_S	522_Q	0.650	0.84
50_R	276_I	0.650	0.84
487_E	490_T	0.650	0.84
23_G	367_A	0.647	0.84
588_V	593_Q	0.647	0.84
244_L	303_L	0.646	0.84
540_L	543_L	0.646	0.84
546_A	562_I	0.645	0.83
100_Y	103_L	0.645	0.83
536_A	572_V	0.645	0.83
580_A	594_D	0.645	0.83
108_Q	116_M	0.644	0.83
31_S	133_I	0.642	0.83
158_A	211_G	0.642	0.83
508_E	512_M	0.639	0.83
128_R	174_L	0.638	0.83
279_S	297_R	0.638	0.83
166_Q	169_K	0.638	0.83
152_V	177_L	0.637	0.83
308_V	344_V	0.633	0.82
403_G	446_Q	0.633	0.82
368_I	372_I	0.633	0.82
95_D	99_R	0.632	0.82
536_A	540_L	0.632	0.82
119_T	122_G	0.631	0.82
589_D	597_A	0.631	0.82
55_S	86_K	0.630	0.82
454_F	496_I	0.629	0.82
168_T	212_T	0.628	0.82
335_V	365_V	0.628	0.82
301_N	304_I	0.628	0.82
585_I	592_T	0.627	0.82
511_S	514_K	0.627	0.82
558_E	562_I	0.627	0.82
582_E	585_I	0.627	0.82
206_Y	312_L	0.626	0.82
591_Q	598_R	0.624	0.81
224_V	389_L	0.624	0.81
170_D	504_L	0.623	0.81
231_G	318_A	0.621	0.81
216_S	239_D	0.619	0.81
536_A	581_I	0.619	0.81
257_D	260_D	0.618	0.81
295_I	299_Q	0.618	0.81
558_E	565_A	0.617	0.81
199_Q	330_L	0.616	0.81
28_T	86_K	0.616	0.81
473_F	481_L	0.615	0.80
577_D	582_E	0.612	0.80
277_A	281_A	0.611	0.80
560_Q	567_A	0.609	0.80
582_E	588_V	0.609	0.80
334_M	356_P	0.608	0.80
92_S	113_G	0.608	0.80
589_D	594_D	0.608	0.80
535_E	538_R	0.607	0.80
249_I	274_A	0.606	0.80
396_L	473_F	0.606	0.80
195_L	333_V	0.606	0.80
579_D	589_D	0.605	0.79
569_L	588_V	0.605	0.79
29_T	367_A	0.604	0.79
278_L	297_R	0.604	0.79
442_R	447_D	0.604	0.79
556_A	564_D	0.604	0.79
576_D	581_I	0.603	0.79
168_T	186_P	0.602	0.79
391_V	412_N	0.601	0.79
376_I	379_G	0.601	0.79
231_G	234_S	0.600	0.79
208_L	338_S	0.600	0.79
189_A	335_V	0.600	0.79
589_D	599_R	0.600	0.79
206_Y	213_F	0.600	0.79
472_T	486_M	0.599	0.79
578_V	598_R	0.599	0.79
597_A	600_M	0.597	0.79
568_H	571_E	0.595	0.78
169_K	182_L	0.594	0.78
580_A	588_V	0.593	0.78
592_T	600_M	0.593	0.78
338_S	363_D	0.592	0.78
151_G	378_V	0.592	0.78
160_F	164_Q	0.591	0.78
588_V	594_D	0.590	0.78
475_V	481_L	0.589	0.78
331_E	359_S	0.588	0.77
437_V	440_G	0.588	0.77
150_D	178_H	0.585	0.77
425_T	463_P	0.585	0.77
124_L	519_Y	0.584	0.77
435_I	454_F	0.584	0.77
504_L	509_I	0.584	0.77
23_G	27_G	0.583	0.77
36_V	39_G	0.582	0.77
168_T	214_D	0.582	0.77
285_T	293_G	0.580	0.77
334_M	358_T	0.580	0.77
273_A	276_I	0.580	0.77
580_A	589_D	0.580	0.77
297_R	342_P	0.579	0.76
553_L	599_R	0.579	0.76
220_L	225_F	0.578	0.76
499_K	506_D	0.577	0.76
320_K	323_G	0.577	0.76
430_Q	465_G	0.576	0.76
250_R	257_D	0.576	0.76
581_I	596_A	0.575	0.76
516_S	519_Y	0.575	0.76
271_A	286_V	0.574	0.76
68_Y	72_T	0.574	0.76
160_F	168_T	0.572	0.76
394_L	442_R	0.572	0.76
153_V	374_A	0.571	0.75
88_L	99_R	0.569	0.75
189_A	366_V	0.569	0.75
392_I	396_L	0.568	0.75
525_K	529_L	0.568	0.75
558_E	595_F	0.567	0.75
28_T	212_T	0.566	0.75
580_A	590_K	0.565	0.75
526_A	529_L	0.564	0.75
550_D	562_I	0.564	0.75
186_P	189_A	0.564	0.75
578_V	594_D	0.563	0.74
283_S	296_S	0.563	0.74
241_F	338_S	0.563	0.74
193_Y	365_V	0.562	0.74
587_N	595_F	0.562	0.74
242_D	275_K	0.562	0.74
265_R	269_D	0.562	0.74
208_L	339_T	0.561	0.74
409_I	413_T	0.561	0.74
246_A	250_R	0.560	0.74
332_V	352_F	0.560	0.74
253_A	263_V	0.559	0.74
98_Q	107_F	0.559	0.74
594_D	600_M	0.558	0.74
515_D	519_Y	0.558	0.74
53_L	137_L	0.558	0.74
308_V	311_T	0.558	0.74
405_V	448_C	0.557	0.74
564_D	571_E	0.557	0.74
536_A	541_E	0.556	0.73
76_L	262_R	0.556	0.73
86_K	130_S	0.556	0.73
441_E	448_C	0.556	0.73
541_E	544_H	0.555	0.73
189_A	212_T	0.555	0.73
594_D	599_R	0.555	0.73
546_A	592_T	0.553	0.73
544_H	563_D	0.553	0.73
400_T	404_L	0.553	0.73
543_L	554_L	0.551	0.73
282_D	297_R	0.550	0.73
578_V	584_A	0.550	0.73
91_R	164_Q	0.550	0.73
128_R	512_M	0.550	0.73
585_I	593_Q	0.549	0.73
212_T	240_D	0.549	0.73
400_T	421_Q	0.548	0.72
281_A	284_V	0.548	0.72
578_V	585_I	0.548	0.72
145_L	149_L	0.547	0.72
410_P	413_T	0.547	0.72
184_N	230_T	0.547	0.72
392_I	409_I	0.546	0.72
472_T	484_T	0.546	0.72
395_S	405_V	0.545	0.72
208_L	311_T	0.545	0.72
533_K	540_L	0.544	0.72
429_G	593_Q	0.543	0.72
36_V	381_K	0.542	0.72
248_Y	251_E	0.542	0.72
536_A	573_A	0.542	0.72
576_D	587_N	0.542	0.72
99_R	103_L	0.542	0.72
556_A	561_V	0.541	0.71
284_V	295_I	0.541	0.71
198_G	357_L	0.541	0.71
35_T	144_A	0.540	0.71
558_E	594_D	0.539	0.71
88_L	96_I	0.538	0.71
487_E	491_G	0.538	0.71
532_Q	536_A	0.538	0.71
309_K	313_L	0.538	0.71
538_R	542_S	0.537	0.71
71_R	272_I	0.537	0.71
37_R	144_A	0.537	0.71
31_S	212_T	0.537	0.71
203_I	331_E	0.536	0.71
236_L	240_D	0.536	0.71
87_R	232_G	0.536	0.71
572_V	577_D	0.535	0.71
438_M	453_R	0.535	0.71
158_A	212_T	0.534	0.70
570_S	576_D	0.532	0.70
529_L	572_V	0.531	0.70
235_A	315_C	0.531	0.70
586_K	599_R	0.530	0.70
582_E	594_D	0.530	0.70
107_F	115_P	0.530	0.70
75_A	265_R	0.529	0.70
340_R	364_K	0.528	0.70
561_V	568_H	0.528	0.70
536_A	539_V	0.528	0.70
227_V	390_D	0.528	0.70
311_T	344_V	0.527	0.69
24_I	27_G	0.527	0.69
89_M	127_V	0.527	0.69
395_S	411_R	0.527	0.69
88_L	103_L	0.527	0.69
278_L	284_V	0.525	0.69
551_A	563_D	0.525	0.69
552_A	560_Q	0.525	0.69
170_D	174_L	0.525	0.69
275_K	338_S	0.524	0.69
561_V	587_N	0.524	0.69
33_V	140_R	0.524	0.69
169_K	478_D	0.524	0.69
208_L	344_V	0.523	0.69
499_K	502_Y	0.522	0.69
24_I	154_I	0.522	0.69
526_A	531_E	0.522	0.69
484_T	491_G	0.522	0.69
535_E	541_E	0.522	0.69
563_D	571_E	0.521	0.69
532_Q	573_A	0.520	0.68
578_V	596_A	0.519	0.68
73_N	81_T	0.518	0.68
210_G	214_D	0.518	0.68
157_P	160_F	0.518	0.68
233_D	313_L	0.518	0.68
152_V	179_V	0.517	0.68
543_L	550_D	0.516	0.68
169_K	173_R	0.516	0.68
581_I	593_Q	0.516	0.68
204_A	329_V	0.516	0.68
588_V	599_R	0.516	0.68
562_I	569_L	0.515	0.68
253_A	257_D	0.515	0.68
568_H	583_Q	0.515	0.68
30_N	84_S	0.515	0.68
583_Q	590_K	0.514	0.68
204_A	332_V	0.514	0.68
566_A	569_L	0.514	0.68
68_Y	276_I	0.514	0.68
593_Q	599_R	0.514	0.68
286_V	293_G	0.513	0.67
565_A	590_K	0.513	0.67
581_I	599_R	0.513	0.67
567_A	590_K	0.513	0.67
458_G	492_V	0.512	0.67
587_N	592_T	0.512	0.67
168_T	185_E	0.512	0.67
226_E	389_L	0.512	0.67
582_E	596_A	0.511	0.67
543_L	589_D	0.511	0.67
94_A	110_S	0.511	0.67
205_V	333_V	0.511	0.67
409_I	417_V	0.510	0.67
562_I	566_A	0.510	0.67
580_A	592_T	0.508	0.67
552_A	563_D	0.507	0.67
193_Y	360_I	0.507	0.67
155_T	183_L	0.506	0.66
139_A	329_V	0.506	0.66
48_E	68_Y	0.506	0.66
539_V	542_S	0.506	0.66
423_F	471_V	0.506	0.66
550_D	596_A	0.505	0.66
460_P	487_E	0.504	0.66
396_L	440_G	0.504	0.66
408_V	423_F	0.504	0.66
124_L	128_R	0.503	0.66
525_K	577_D	0.503	0.66
566_A	572_V	0.503	0.66
533_K	536_A	0.503	0.66
269_D	273_A	0.503	0.66
547_L	599_R	0.502	0.66
486_M	491_G	0.502	0.66
96_I	111_E	0.501	0.66
573_A	585_I	0.501	0.66
573_A	576_D	0.500	0.65
554_L	595_F	0.500	0.65
519_Y	523_D	0.500	0.65
564_D	582_E	0.500	0.65

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3d2fA	1	0.9659	100	0.171	Contact Map
4jneA	2	0.9383	100	0.185	Contact Map
4fl9A	1	0.8425	100	0.23	Contact Map
2v7yA	1	0.7955	100	0.276	Contact Map
4rtfD	1	0.5438	100	0.293	Contact Map
3i33A	1	0.5828	100	0.48	Contact Map
4kboA	1	0.5828	100	0.483	Contact Map
4j8fA	2	0.8539	100	0.5	Contact Map
4gniA	2	0.5812	100	0.527	Contact Map
3qfuA	1	0.586	100	0.549	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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