GREMLIN Database
HSCA - Chaperone protein HscA
UniProt: P0A6Z1 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12130
Length: 616 (578)
Sequences: 6671 (3254)
Seq/√Len: 135.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
151_G178_H5.3191.00
233_D310_R4.8301.00
244_L306_P4.7091.00
245_L295_I3.7321.00
349_G355_P3.6351.00
206_Y311_T3.6311.00
283_S294_E3.4401.00
346_E350_E3.4091.00
252_Q299_Q3.2661.00
84_S239_D3.2461.00
217_I318_A3.1951.00
46_D53_L2.9541.00
544_H570_S2.9091.00
50_R68_Y2.9021.00
506_D510_A2.8831.00
395_S407_K2.8671.00
406_E423_F2.8031.00
118_E123_L2.7791.00
434_S455_A2.7461.00
436_H450_S2.7221.00
577_D580_A2.7201.00
250_R258_R2.6891.00
361_D364_K2.6411.00
249_I293_G2.5641.00
151_G180_L2.5421.00
407_K410_P2.5411.00
229_A318_A2.4941.00
519_Y522_Q2.4541.00
345_R358_T2.4231.00
118_E121_A2.4191.00
299_Q302_E2.3831.00
106_Q118_E2.2961.00
208_L241_F2.2891.00
560_Q564_D2.2801.00
249_I271_A2.2551.00
305_A309_K2.2371.00
21_A180_L2.2351.00
517_M520_A2.2291.00
582_E586_K2.2261.00
138_A142_T2.2091.00
204_A217_I2.1751.00
567_A571_E2.1461.00
486_M493_E2.1171.00
338_S341_V2.1111.00
204_A215_I2.1031.00
511_S515_D2.0921.00
304_I341_V2.0821.00
551_A559_R2.0791.00
312_L351_F2.0731.00
397_G405_V2.0711.00
85_V117_I2.0691.00
79_A106_Q2.0611.00
308_V343_L2.0411.00
555_S558_E2.0111.00
438_M450_S2.0101.00
521_E525_K2.0091.00
241_F307_L1.9911.00
563_D567_A1.9671.00
285_T292_Q1.9591.00
347_R350_E1.9471.00
571_E574_Q1.9311.00
524_V528_M1.9171.00
243_H247_D1.9141.00
139_A143_E1.9101.00
580_A584_A1.8971.00
313_L317_R1.8891.00
536_A569_L1.8851.00
514_K518_S1.8841.00
124_L129_V1.8751.00
22_A33_V1.8701.00
37_R42_E1.8681.00
586_K590_K1.8611.00
578_V582_E1.8571.00
246_A268_L1.8551.00
558_E598_R1.8461.00
34_A371_A1.8421.00
594_D597_A1.8371.00
155_T370_A1.8331.00
166_Q170_D1.7931.00
300_F341_V1.7901.00
301_N346_E1.7871.00
340_R363_D1.7751.00
21_A374_A1.7481.00
296_S299_Q1.7461.00
316_R351_F1.7431.00
201_G331_E1.7231.00
272_I276_I1.7101.00
173_R178_H1.7101.00
592_T596_A1.7051.00
79_A261_N1.7031.00
132_D135_K1.6871.00
434_S453_R1.6771.00
31_S137_L1.6711.00
556_A560_Q1.6691.00
325_E328_E1.6661.00
543_L592_T1.6651.00
514_K517_M1.6571.00
313_L316_R1.6271.00
32_L52_L1.6271.00
312_L316_R1.6091.00
436_H453_R1.6041.00
80_N120_A1.5941.00
400_T406_E1.5921.00
217_I329_V1.5921.00
510_A514_K1.5901.00
270_A274_A1.5891.00
274_A284_V1.5861.00
97_Q100_Y1.5701.00
584_A587_N1.5661.00
51_H364_K1.5611.00
589_D593_Q1.5611.00
564_D568_H1.5601.00
94_A113_G1.5561.00
136_A140_R1.5501.00
300_F338_S1.5341.00
594_D598_R1.5341.00
32_L43_T1.5241.00
127_V170_D1.5101.00
304_I308_V1.5101.00
420_A470_R1.5051.00
302_E305_A1.5031.00
559_R563_D1.5011.00
420_A472_T1.4991.00
249_I286_V1.4941.00
540_L570_S1.4901.00
44_L144_A1.4871.00
565_A568_H1.4861.00
316_R320_K1.4801.00
389_L414_T1.4761.00
173_R506_D1.4751.00
581_I588_V1.4711.00
444_L447_D1.4661.00
59_Y132_D1.4651.00
245_L271_A1.4541.00
331_E357_L1.4491.00
244_L304_I1.4411.00
202_V219_R1.4401.00
584_A588_V1.4391.00
299_Q303_L1.4331.00
568_H584_A1.4321.00
208_L213_F1.4261.00
249_I267_L1.4191.00
248_Y303_L1.4151.00
170_D173_R1.4121.00
444_L530_A1.4021.00
248_Y299_Q1.4011.00
130_S168_T1.3991.00
58_H73_N1.3951.00
407_K443_E1.3941.00
515_D518_S1.3931.00
33_V137_L1.3911.00
88_L117_I1.3791.00
83_S104_P1.3791.00
77_D80_N1.3791.00
312_L347_R1.3761.00
274_A286_V1.3761.00
34_A367_A1.3701.00
468_H488_K1.3641.00
110_S113_G1.3631.00
317_R321_D1.3621.00
585_I589_D1.3481.00
154_I172_A1.3471.00
565_A569_L1.3461.00
399_E436_H1.3421.00
85_V133_I1.3411.00
505_T508_E1.3391.00
450_S453_R1.3381.00
137_L140_R1.3381.00
406_E421_Q1.3291.00
172_A182_L1.3241.00
570_S574_Q1.3241.00
558_E561_V1.3211.00
43_T368_I1.3201.00
319_L326_A1.3171.00
26_L168_T1.3141.00
82_I119_T1.3111.00
248_Y252_Q1.3101.00
508_E511_S1.3091.00
535_E585_I1.3061.00
413_T417_V1.2921.00
85_V130_S1.2911.00
593_Q597_A1.2891.00
586_K589_D1.2881.00
583_Q587_N1.2831.00
85_V129_V1.2821.00
422_D470_R1.2771.00
346_E349_G1.2761.00
520_A524_V1.2741.00
540_L566_A1.2711.00
392_I475_V1.2711.00
247_D258_R1.2701.00
252_Q293_G1.2691.00
73_N77_D1.2691.00
577_D588_V1.2671.00
565_A591_Q1.2661.00
593_Q596_A1.2661.00
36_V375_D1.2661.00
111_E116_M1.2611.00
217_I324_V1.2601.00
556_A563_D1.2561.00
581_I584_A1.2501.00
82_I129_V1.2461.00
26_L134_L1.2331.00
587_N591_Q1.2281.00
274_A295_I1.2241.00
565_A587_N1.2201.00
317_R320_K1.2181.00
308_V347_R1.2161.00
57_V129_V1.2121.00
138_A177_L1.2101.00
241_F300_F1.2091.00
202_V324_V1.2091.00
521_E524_V1.2081.00
297_R301_N1.2061.00
534_V541_E1.2011.00
47_H140_R1.1981.00
544_H548_A1.1981.00
41_A368_I1.1941.00
231_G314_A1.1931.00
540_L569_L1.1911.00
128_R132_D1.1860.99
527_R531_E1.1850.99
532_Q585_I1.1840.99
93_L97_Q1.1840.99
247_D251_E1.1740.99
204_A315_C1.1730.99
432_A455_A1.1670.99
270_A273_A1.1670.99
251_E258_R1.1660.99
59_Y119_T1.1590.99
588_V598_R1.1570.99
590_K593_Q1.1540.99
56_V83_S1.1540.99
108_Q118_E1.1530.99
246_A271_A1.1530.99
248_Y293_G1.1520.99
228_L324_V1.1520.99
529_L576_D1.1480.99
588_V592_T1.1410.99
131_A174_L1.1410.99
241_F304_I1.1330.99
348_V356_P1.1320.99
578_V581_I1.1310.99
241_F341_V1.1280.99
31_S55_S1.1240.99
184_N187_T1.1230.99
169_K480_L1.1230.99
405_V438_M1.1160.99
579_D583_Q1.1150.99
231_G317_R1.1150.99
28_T211_G1.1120.99
305_A343_L1.1100.99
577_D581_I1.1060.99
59_Y124_L1.1040.99
219_R228_L1.1010.99
592_T598_R1.1010.99
100_Y107_F1.0940.99
180_L377_L1.0940.99
438_M445_V1.0920.99
321_D411_R1.0910.99
86_K185_E1.0900.99
561_V591_Q1.0900.99
29_T210_G1.0880.99
589_D592_T1.0850.99
561_V594_D1.0850.99
277_A284_V1.0830.99
418_A472_T1.0810.99
45_A51_H1.0790.99
252_Q255_I1.0770.99
343_L346_E1.0750.99
36_V41_A1.0700.99
547_L559_R1.0680.99
532_Q582_E1.0670.99
172_A179_V1.0640.99
89_M168_T1.0620.99
596_A599_R1.0610.99
87_R240_D1.0560.99
568_H587_N1.0540.99
542_S546_A1.0540.99
97_Q101_P1.0500.99
20_L147_G1.0480.99
26_L130_S1.0470.99
244_L247_D1.0420.99
61_Q120_A1.0420.99
243_H268_L1.0370.99
432_A457_R1.0360.99
522_Q525_K1.0300.99
550_D599_R1.0290.99
184_N390_D1.0250.98
250_R267_L1.0250.98
579_D582_E1.0240.98
248_Y295_I1.0190.98
583_Q586_K1.0190.98
202_V228_L1.0180.98
557_A561_V1.0150.98
82_I85_V1.0150.98
287_N292_Q1.0140.98
422_D488_K1.0140.98
428_D464_A1.0130.98
22_A152_V1.0120.98
213_F311_T1.0110.98
165_R184_N1.0100.98
161_D164_Q1.0090.98
324_V328_E1.0080.98
575_G580_A1.0080.98
186_P214_D1.0080.98
343_L347_R1.0060.98
162_D166_Q0.9980.98
319_L324_V0.9970.98
142_T148_E0.9950.98
560_Q563_D0.9850.98
561_V565_A0.9840.98
116_M125_N0.9830.98
135_K139_A0.9800.98
572_V584_A0.9780.98
512_M515_D0.9750.98
418_A474_Q0.9720.98
561_V564_D0.9710.98
252_Q291_W0.9690.98
318_A322_A0.9660.98
580_A583_Q0.9640.98
460_P489_S0.9630.98
537_A541_E0.9620.98
260_D263_V0.9610.98
124_L132_D0.9580.98
539_V543_L0.9580.98
581_I592_T0.9550.98
315_C351_F0.9550.98
528_M582_E0.9520.98
316_R326_A0.9490.98
588_V591_Q0.9470.97
270_A284_V0.9470.97
266_E270_A0.9460.97
533_K573_A0.9450.97
399_E403_G0.9450.97
590_K594_D0.9440.97
564_D567_A0.9440.97
577_D598_R0.9420.97
43_T51_H0.9390.97
249_I295_I0.9380.97
568_H572_V0.9380.97
241_F308_V0.9380.97
428_D465_G0.9370.97
395_S441_E0.9360.97
577_D584_A0.9350.97
34_A43_T0.9350.97
544_H566_A0.9350.97
309_K347_R0.9340.97
581_I585_I0.9330.97
45_A144_A0.9290.97
304_I307_L0.9290.97
581_I598_R0.9240.97
591_Q594_D0.9240.97
571_E575_G0.9230.97
547_L566_A0.9220.97
317_R411_R0.9220.97
108_Q123_L0.9210.97
286_V295_I0.9200.97
543_L562_I0.9170.97
585_I588_V0.9170.97
349_G356_P0.9120.97
314_A318_A0.9080.97
584_A589_D0.9060.97
100_Y106_Q0.9030.97
215_I318_A0.9000.97
476_D482_S0.8990.97
243_H246_A0.8950.96
532_Q535_E0.8930.96
110_S116_M0.8930.96
249_I291_W0.8900.96
572_V575_G0.8890.96
270_A277_A0.8850.96
562_I591_Q0.8840.96
154_I179_V0.8830.96
60_Q63_G0.8790.96
245_L248_Y0.8790.96
304_I343_L0.8790.96
554_L559_R0.8760.96
229_A322_A0.8730.96
539_V585_I0.8730.96
244_L307_L0.8710.96
531_E535_E0.8700.96
557_A560_Q0.8690.96
543_L566_A0.8680.96
218_L227_V0.8670.96
572_V576_D0.8650.96
547_L563_D0.8650.96
572_V580_A0.8630.96
185_E214_D0.8620.96
452_A498_V0.8590.96
295_I300_F0.8560.95
98_Q102_H0.8550.95
285_T294_E0.8530.95
463_P466_G0.8530.95
253_A291_W0.8510.95
545_G549_A0.8490.95
584_A598_R0.8390.95
581_I589_D0.8370.95
373_Q376_I0.8360.95
562_I592_T0.8360.95
462_L487_E0.8360.95
593_Q600_M0.8360.95
77_D81_T0.8340.95
35_T145_L0.8340.95
208_L307_L0.8310.95
401_M426_F0.8300.95
462_L467_A0.8290.95
489_S600_M0.8280.95
202_V330_L0.8270.95
425_T430_Q0.8270.95
204_A352_F0.8230.94
596_A600_M0.8220.94
529_L532_Q0.8220.94
21_A151_G0.8210.94
116_M123_L0.8190.94
592_T599_R0.8160.94
528_M578_V0.8160.94
246_A264_Q0.8150.94
533_K576_D0.8150.94
51_H361_D0.8120.94
535_E589_D0.8110.94
158_A186_P0.8110.94
301_N343_L0.8080.94
58_H77_D0.8080.94
315_C348_V0.8070.94
173_R513_I0.8060.94
550_D554_L0.8050.94
139_A142_T0.8040.94
312_L315_C0.8020.94
556_A559_R0.8020.94
584_A591_Q0.8020.94
546_A550_D0.8000.93
534_V538_R0.8000.93
569_L581_I0.7980.93
589_D596_A0.7960.93
474_Q482_S0.7960.93
231_G321_D0.7960.93
584_A594_D0.7960.93
569_L584_A0.7880.93
555_S598_R0.7880.93
529_L533_K0.7870.93
56_V71_R0.7870.93
425_T465_G0.7860.93
540_L573_A0.7860.93
554_L558_E0.7830.93
89_M130_S0.7830.93
140_R143_E0.7830.93
510_A513_I0.7800.93
458_G462_L0.7800.93
433_M469_I0.7790.93
250_R264_Q0.7770.92
22_A141_A0.7770.92
158_A214_D0.7770.92
98_Q101_P0.7750.92
357_L365_V0.7700.92
470_R486_M0.7690.92
156_V182_L0.7650.92
560_Q571_E0.7650.92
99_R235_A0.7640.92
211_G214_D0.7640.92
85_V89_M0.7630.92
46_D140_R0.7590.92
25_D28_T0.7590.92
58_H65_S0.7570.91
422_D468_H0.7570.91
560_Q568_H0.7560.91
539_V589_D0.7550.91
86_K211_G0.7550.91
60_Q64_H0.7540.91
251_E254_G0.7530.91
504_L512_M0.7510.91
315_C352_F0.7490.91
201_G330_L0.7490.91
567_A574_Q0.7470.91
181_R373_Q0.7470.91
575_G581_I0.7460.91
592_T595_F0.7460.91
122_G128_R0.7440.91
578_V592_T0.7440.91
80_N119_T0.7410.91
34_A41_A0.7410.91
171_A175_A0.7400.91
266_E288_V0.7400.91
589_D598_R0.7390.90
22_A149_L0.7380.90
217_I322_A0.7380.90
471_V483_V0.7370.90
578_V588_V0.7370.90
91_R95_D0.7360.90
595_F598_R0.7350.90
548_A551_A0.7350.90
529_L573_A0.7340.90
425_T428_D0.7340.90
443_E527_R0.7340.90
257_D263_V0.7320.90
88_L93_L0.7320.90
537_A570_S0.7290.90
530_A533_K0.7280.90
53_L140_R0.7250.90
319_L329_V0.7250.90
525_K528_M0.7230.90
424_T467_A0.7220.89
566_A570_S0.7210.89
532_Q578_V0.7210.89
180_L374_A0.7200.89
136_A139_A0.7160.89
537_A573_A0.7160.89
258_R264_Q0.7150.89
535_E540_L0.7140.89
580_A598_R0.7140.89
330_L354_R0.7130.89
375_D381_K0.7130.89
577_D585_I0.7110.89
545_G548_A0.7100.89
156_V165_R0.7090.89
154_I168_T0.7080.89
387_L477_A0.7070.88
556_A567_A0.7070.88
93_L100_Y0.7060.88
592_T597_A0.7040.88
21_A378_V0.7030.88
584_A592_T0.7030.88
587_N590_K0.7030.88
582_E587_N0.7010.88
462_L466_G0.7000.88
536_A585_I0.7000.88
347_R351_F0.7000.88
156_V184_N0.6980.88
442_R523_D0.6980.88
186_P212_T0.6970.88
134_L168_T0.6970.88
593_Q598_R0.6960.88
470_R488_K0.6930.87
110_S114_L0.6920.87
581_I591_Q0.6910.87
525_K579_D0.6890.87
224_V387_L0.6890.87
581_I594_D0.6850.87
437_V473_F0.6840.87
26_L363_D0.6830.87
221_S224_V0.6830.87
326_A351_F0.6810.87
111_E123_L0.6810.87
309_K312_L0.6790.86
114_L127_V0.6790.86
198_G201_G0.6780.86
273_A277_A0.6780.86
61_Q64_H0.6770.86
202_V329_V0.6760.86
553_L558_E0.6750.86
213_F236_L0.6750.86
577_D589_D0.6740.86
582_E590_K0.6730.86
233_D236_L0.6720.86
88_L91_R0.6710.86
548_A563_D0.6700.86
155_T366_V0.6690.86
46_D51_H0.6690.86
572_V581_I0.6680.85
301_N341_V0.6670.85
424_T468_H0.6670.85
59_Y129_V0.6660.85
47_H136_A0.6660.85
377_L477_A0.6660.85
440_G448_C0.6640.85
528_M531_E0.6630.85
400_T423_F0.6630.85
334_M348_V0.6630.85
246_A267_L0.6610.85
127_V167_G0.6600.85
89_M167_G0.6590.85
533_K537_A0.6580.85
532_Q541_E0.6580.85
279_S342_P0.6580.85
135_K138_A0.6560.84
24_I152_V0.6560.84
191_I386_M0.6530.84
399_E438_M0.6530.84
595_F600_M0.6520.84
567_A570_S0.6510.84
518_S522_Q0.6500.84
50_R276_I0.6500.84
487_E490_T0.6500.84
23_G367_A0.6470.84
588_V593_Q0.6470.84
244_L303_L0.6460.84
540_L543_L0.6460.84
546_A562_I0.6450.83
100_Y103_L0.6450.83
536_A572_V0.6450.83
580_A594_D0.6450.83
108_Q116_M0.6440.83
31_S133_I0.6420.83
158_A211_G0.6420.83
508_E512_M0.6390.83
128_R174_L0.6380.83
279_S297_R0.6380.83
166_Q169_K0.6380.83
152_V177_L0.6370.83
308_V344_V0.6330.82
403_G446_Q0.6330.82
368_I372_I0.6330.82
95_D99_R0.6320.82
536_A540_L0.6320.82
119_T122_G0.6310.82
589_D597_A0.6310.82
55_S86_K0.6300.82
454_F496_I0.6290.82
168_T212_T0.6280.82
335_V365_V0.6280.82
301_N304_I0.6280.82
585_I592_T0.6270.82
511_S514_K0.6270.82
558_E562_I0.6270.82
582_E585_I0.6270.82
206_Y312_L0.6260.82
591_Q598_R0.6240.81
224_V389_L0.6240.81
170_D504_L0.6230.81
231_G318_A0.6210.81
216_S239_D0.6190.81
536_A581_I0.6190.81
257_D260_D0.6180.81
295_I299_Q0.6180.81
558_E565_A0.6170.81
199_Q330_L0.6160.81
28_T86_K0.6160.81
473_F481_L0.6150.80
577_D582_E0.6120.80
277_A281_A0.6110.80
560_Q567_A0.6090.80
582_E588_V0.6090.80
334_M356_P0.6080.80
92_S113_G0.6080.80
589_D594_D0.6080.80
535_E538_R0.6070.80
249_I274_A0.6060.80
396_L473_F0.6060.80
195_L333_V0.6060.80
579_D589_D0.6050.79
569_L588_V0.6050.79
29_T367_A0.6040.79
278_L297_R0.6040.79
442_R447_D0.6040.79
556_A564_D0.6040.79
576_D581_I0.6030.79
168_T186_P0.6020.79
391_V412_N0.6010.79
376_I379_G0.6010.79
231_G234_S0.6000.79
208_L338_S0.6000.79
189_A335_V0.6000.79
589_D599_R0.6000.79
206_Y213_F0.6000.79
472_T486_M0.5990.79
578_V598_R0.5990.79
597_A600_M0.5970.79
568_H571_E0.5950.78
169_K182_L0.5940.78
580_A588_V0.5930.78
592_T600_M0.5930.78
338_S363_D0.5920.78
151_G378_V0.5920.78
160_F164_Q0.5910.78
588_V594_D0.5900.78
475_V481_L0.5890.78
331_E359_S0.5880.77
437_V440_G0.5880.77
150_D178_H0.5850.77
425_T463_P0.5850.77
124_L519_Y0.5840.77
435_I454_F0.5840.77
504_L509_I0.5840.77
23_G27_G0.5830.77
36_V39_G0.5820.77
168_T214_D0.5820.77
285_T293_G0.5800.77
334_M358_T0.5800.77
273_A276_I0.5800.77
580_A589_D0.5800.77
297_R342_P0.5790.76
553_L599_R0.5790.76
220_L225_F0.5780.76
499_K506_D0.5770.76
320_K323_G0.5770.76
430_Q465_G0.5760.76
250_R257_D0.5760.76
581_I596_A0.5750.76
516_S519_Y0.5750.76
271_A286_V0.5740.76
68_Y72_T0.5740.76
160_F168_T0.5720.76
394_L442_R0.5720.76
153_V374_A0.5710.75
88_L99_R0.5690.75
189_A366_V0.5690.75
392_I396_L0.5680.75
525_K529_L0.5680.75
558_E595_F0.5670.75
28_T212_T0.5660.75
580_A590_K0.5650.75
526_A529_L0.5640.75
550_D562_I0.5640.75
186_P189_A0.5640.75
578_V594_D0.5630.74
283_S296_S0.5630.74
241_F338_S0.5630.74
193_Y365_V0.5620.74
587_N595_F0.5620.74
242_D275_K0.5620.74
265_R269_D0.5620.74
208_L339_T0.5610.74
409_I413_T0.5610.74
246_A250_R0.5600.74
332_V352_F0.5600.74
253_A263_V0.5590.74
98_Q107_F0.5590.74
594_D600_M0.5580.74
515_D519_Y0.5580.74
53_L137_L0.5580.74
308_V311_T0.5580.74
405_V448_C0.5570.74
564_D571_E0.5570.74
536_A541_E0.5560.73
76_L262_R0.5560.73
86_K130_S0.5560.73
441_E448_C0.5560.73
541_E544_H0.5550.73
189_A212_T0.5550.73
594_D599_R0.5550.73
546_A592_T0.5530.73
544_H563_D0.5530.73
400_T404_L0.5530.73
543_L554_L0.5510.73
282_D297_R0.5500.73
578_V584_A0.5500.73
91_R164_Q0.5500.73
128_R512_M0.5500.73
585_I593_Q0.5490.73
212_T240_D0.5490.73
400_T421_Q0.5480.72
281_A284_V0.5480.72
578_V585_I0.5480.72
145_L149_L0.5470.72
410_P413_T0.5470.72
184_N230_T0.5470.72
392_I409_I0.5460.72
472_T484_T0.5460.72
395_S405_V0.5450.72
208_L311_T0.5450.72
533_K540_L0.5440.72
429_G593_Q0.5430.72
36_V381_K0.5420.72
248_Y251_E0.5420.72
536_A573_A0.5420.72
576_D587_N0.5420.72
99_R103_L0.5420.72
556_A561_V0.5410.71
284_V295_I0.5410.71
198_G357_L0.5410.71
35_T144_A0.5400.71
558_E594_D0.5390.71
88_L96_I0.5380.71
487_E491_G0.5380.71
532_Q536_A0.5380.71
309_K313_L0.5380.71
538_R542_S0.5370.71
71_R272_I0.5370.71
37_R144_A0.5370.71
31_S212_T0.5370.71
203_I331_E0.5360.71
236_L240_D0.5360.71
87_R232_G0.5360.71
572_V577_D0.5350.71
438_M453_R0.5350.71
158_A212_T0.5340.70
570_S576_D0.5320.70
529_L572_V0.5310.70
235_A315_C0.5310.70
586_K599_R0.5300.70
582_E594_D0.5300.70
107_F115_P0.5300.70
75_A265_R0.5290.70
340_R364_K0.5280.70
561_V568_H0.5280.70
536_A539_V0.5280.70
227_V390_D0.5280.70
311_T344_V0.5270.69
24_I27_G0.5270.69
89_M127_V0.5270.69
395_S411_R0.5270.69
88_L103_L0.5270.69
278_L284_V0.5250.69
551_A563_D0.5250.69
552_A560_Q0.5250.69
170_D174_L0.5250.69
275_K338_S0.5240.69
561_V587_N0.5240.69
33_V140_R0.5240.69
169_K478_D0.5240.69
208_L344_V0.5230.69
499_K502_Y0.5220.69
24_I154_I0.5220.69
526_A531_E0.5220.69
484_T491_G0.5220.69
535_E541_E0.5220.69
563_D571_E0.5210.69
532_Q573_A0.5200.68
578_V596_A0.5190.68
73_N81_T0.5180.68
210_G214_D0.5180.68
157_P160_F0.5180.68
233_D313_L0.5180.68
152_V179_V0.5170.68
543_L550_D0.5160.68
169_K173_R0.5160.68
581_I593_Q0.5160.68
204_A329_V0.5160.68
588_V599_R0.5160.68
562_I569_L0.5150.68
253_A257_D0.5150.68
568_H583_Q0.5150.68
30_N84_S0.5150.68
583_Q590_K0.5140.68
204_A332_V0.5140.68
566_A569_L0.5140.68
68_Y276_I0.5140.68
593_Q599_R0.5140.68
286_V293_G0.5130.67
565_A590_K0.5130.67
581_I599_R0.5130.67
567_A590_K0.5130.67
458_G492_V0.5120.67
587_N592_T0.5120.67
168_T185_E0.5120.67
226_E389_L0.5120.67
582_E596_A0.5110.67
543_L589_D0.5110.67
94_A110_S0.5110.67
205_V333_V0.5110.67
409_I417_V0.5100.67
562_I566_A0.5100.67
580_A592_T0.5080.67
552_A563_D0.5070.67
193_Y360_I0.5070.67
155_T183_L0.5060.66
139_A329_V0.5060.66
48_E68_Y0.5060.66
539_V542_S0.5060.66
423_F471_V0.5060.66
550_D596_A0.5050.66
460_P487_E0.5040.66
396_L440_G0.5040.66
408_V423_F0.5040.66
124_L128_R0.5030.66
525_K577_D0.5030.66
566_A572_V0.5030.66
533_K536_A0.5030.66
269_D273_A0.5030.66
547_L599_R0.5020.66
486_M491_G0.5020.66
96_I111_E0.5010.66
573_A585_I0.5010.66
573_A576_D0.5000.65
554_L595_F0.5000.65
519_Y523_D0.5000.65
564_D582_E0.5000.65
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3d2fA 1 0.9659 100 0.171 Contact Map
4jneA 2 0.9383 100 0.185 Contact Map
4fl9A 1 0.8425 100 0.23 Contact Map
2v7yA 1 0.7955 100 0.276 Contact Map
4rtfD 1 0.5438 100 0.293 Contact Map
3i33A 1 0.5828 100 0.48 Contact Map
4kboA 1 0.5828 100 0.483 Contact Map
4j8fA 2 0.8539 100 0.5 Contact Map
4gniA 2 0.5812 100 0.527 Contact Map
3qfuA 1 0.586 100 0.549 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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