GREMLIN Database
DNAK - Chaperone protein DnaK
UniProt: P0A6Y8 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10241
Length: 638 (588)
Sequences: 6370 (2975)
Seq/√Len: 122.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
137_E164_E5.2371.00
224_D315_R4.9411.00
235_R311_D4.5561.00
236_L300_V3.6761.00
354_A360_E3.6401.00
193_Y316_S3.5661.00
278_Q299_K3.5281.00
68_A230_E3.4251.00
351_K355_E3.3791.00
204_I323_A3.1731.00
243_E304_K3.1051.00
398_S410_T3.0011.00
580_D583_A2.9641.00
29_N36_T2.9391.00
241_V253_R2.8421.00
547_R573_E2.8391.00
509_E513_Q2.8321.00
439_H453_S2.8171.00
366_N369_E2.7871.00
104_E109_K2.7381.00
33_D52_Q2.7061.00
437_T458_N2.6791.00
409_T426_F2.6341.00
240_L298_I2.5641.00
137_E166_K2.5331.00
220_A323_A2.5291.00
410_T413_A2.5211.00
350_Q363_K2.5111.00
92_K104_E2.4471.00
304_K307_S2.4261.00
104_E107_G2.3921.00
195_L232_F2.3331.00
522_N525_A2.3241.00
563_T567_S2.2961.00
4_I166_K2.2841.00
240_L266_A2.2751.00
520_E523_A2.2591.00
191_A204_I2.2371.00
310_E314_N2.2081.00
191_A202_I2.2041.00
514_K518_D2.1751.00
78_Q95_A2.1741.00
124_K128_E2.1711.00
343_Q346_M2.1551.00
309_V346_M2.1441.00
570_T574_T2.1221.00
63_Q92_K2.1191.00
313_V348_M2.1121.00
317_I356_F2.1081.00
489_K496_E2.0911.00
400_G408_M2.0761.00
243_E246_K2.0691.00
539_G572_L2.0551.00
234_S238_N2.0501.00
561_D601_I2.0481.00
280_D297_N2.0411.00
69_I103_V2.0361.00
352_K355_E2.0241.00
554_G562_K2.0171.00
232_F312_L2.0091.00
441_L453_S2.0031.00
125_K129_D1.9981.00
318_E322_V1.9641.00
558_P561_D1.9641.00
517_R521_A1.9491.00
5_I16_V1.9411.00
48_T118_E1.9391.00
20_D25_R1.9371.00
600_E604_Q1.9131.00
527_R531_E1.9121.00
237_I263_K1.9101.00
546_T595_S1.8941.00
524_E528_K1.8601.00
574_T577_K1.8521.00
437_T456_Q1.8291.00
4_I379_G1.8261.00
585_E589_Q1.8241.00
17_A376_A1.8161.00
587_K590_E1.8091.00
566_E570_T1.7911.00
305_L343_Q1.7861.00
517_R520_E1.7841.00
571_A587_K1.7641.00
305_L346_M1.7551.00
589_Q593_Q1.7521.00
141_T375_A1.7221.00
63_Q256_P1.7111.00
152_Q156_D1.7071.00
597_K600_E1.6991.00
317_I321_K1.6911.00
269_A281_V1.6911.00
330_S333_D1.6761.00
345_R368_D1.6651.00
306_E351_K1.6581.00
301_T304_K1.6571.00
513_Q517_R1.6561.00
559_A563_T1.6511.00
188_R336_D1.6491.00
83_Q86_V1.6451.00
267_E271_I1.6451.00
269_A279_T1.6371.00
336_D362_R1.6331.00
318_E321_K1.6311.00
15_C35_T1.6301.00
159_R164_E1.6281.00
265_A269_A1.6201.00
110_M115_I1.6131.00
581_K585_E1.6121.00
96_A102_W1.5981.00
583_A587_K1.5921.00
439_H456_Q1.5891.00
240_L281_V1.5881.00
567_S571_A1.5681.00
568_A590_E1.5671.00
562_K566_E1.5661.00
118_E121_K1.5601.00
423_S473_E1.5551.00
34_R369_E1.5541.00
321_K356_F1.5511.00
236_L266_A1.5501.00
592_A596_Q1.5441.00
248_Q294_K1.5411.00
309_V313_V1.5381.00
159_R509_E1.5381.00
321_K325_Q1.5321.00
64_N106_K1.5231.00
392_L417_T1.5171.00
403_T409_T1.5081.00
122_K126_T1.5041.00
307_S310_E1.4951.00
204_I334_I1.4951.00
586_A590_E1.4921.00
242_E253_R1.4891.00
14_S123_M1.4871.00
543_L573_E1.4841.00
15_C26_V1.4821.00
42_Y118_E1.4771.00
240_L262_L1.4751.00
447_R533_V1.4711.00
67_F90_P1.4661.00
471_Q491_K1.4571.00
123_M126_T1.4371.00
568_A571_A1.4321.00
239_Y304_K1.4271.00
573_E577_K1.4021.00
140_I158_G1.4021.00
113_P156_D1.4021.00
252_L286_I1.4001.00
395_T478_I1.3991.00
27_L130_Y1.3901.00
116_S154_T1.3871.00
423_S475_T1.3811.00
304_K308_L1.3791.00
41_A57_Q1.3781.00
235_R309_V1.3681.00
511_E514_K1.3651.00
322_V326_D1.3651.00
410_T446_K1.3631.00
204_I329_L1.3631.00
561_D564_A1.3551.00
543_L569_L1.3461.00
518_D521_A1.3451.00
317_I352_K1.3431.00
453_S456_Q1.3421.00
195_L200_F1.3421.00
158_G168_I1.3351.00
78_Q99_G1.3341.00
156_D159_R1.3331.00
26_V373_I1.3291.00
402_E439_H1.3261.00
239_Y308_L1.3231.00
538_Q588_M1.3221.00
409_T424_Q1.3221.00
324_L331_V1.3221.00
69_I119_V1.3171.00
61_N64_N1.3161.00
17_A372_A1.3121.00
353_V361_P1.3101.00
447_R450_D1.3071.00
586_A589_Q1.3051.00
535_T585_E1.3041.00
582_A586_A1.2991.00
351_K354_A1.2991.00
588_M592_A1.2951.00
189_T206_E1.2951.00
272_E279_T1.2911.00
9_L154_T1.2911.00
95_A99_G1.2911.00
9_L120_L1.2901.00
114_Q118_E1.2891.00
238_N253_R1.2881.00
66_L115_I1.2861.00
416_T420_T1.2811.00
69_I116_S1.2811.00
245_K251_D1.2801.00
595_S599_M1.2711.00
535_T588_M1.2701.00
66_L105_V1.2691.00
242_E245_K1.2641.00
568_A572_L1.2591.00
322_V325_Q1.2571.00
232_F305_L1.2531.00
243_E298_I1.2521.00
3_K133_E1.2490.99
523_A527_R1.2470.99
16_V123_M1.2450.99
568_A594_V1.2450.99
559_A566_E1.2430.99
57_Q61_N1.2410.99
222_N319_P1.2360.99
508_N511_E1.2350.99
575_A587_K1.2310.99
19_M380_G1.2300.99
238_N242_E1.2190.99
265_A268_K1.2150.99
310_E348_M1.2130.99
77_F83_Q1.2100.99
601_I604_Q1.2100.99
313_V352_K1.2090.99
72_L103_V1.2070.99
189_T329_L1.2060.99
191_A320_L1.2050.99
239_Y298_I1.1990.99
232_F346_M1.1940.99
30_A126_T1.1930.99
69_I115_I1.1920.99
239_Y243_E1.1920.99
543_L572_L1.1900.99
536_R576_L1.1890.99
515_M518_D1.1870.99
408_M441_L1.1850.99
425_V473_E1.1790.99
124_K163_L1.1740.99
222_N322_V1.1730.99
42_Y110_M1.1700.99
166_K382_L1.1700.99
524_E527_R1.1680.99
324_L329_L1.1670.99
40_I115_I1.1620.99
547_R551_E1.1610.99
545_S549_Q1.1610.99
530_E534_Q1.1560.99
206_E219_L1.1550.99
323_A327_A1.1530.99
239_Y300_V1.1500.99
219_L329_L1.1500.99
269_A300_V1.1360.99
189_T219_L1.1330.99
155_K483_I1.1310.99
550_V562_K1.1190.99
348_M351_K1.1170.99
463_N492_N1.1160.99
302_R306_E1.1130.99
553_A602_A1.1040.99
94_I104_E1.0990.99
237_I266_A1.0970.99
128_E134_P1.0930.99
596_Q599_M1.0920.99
421_K475_T1.0860.99
322_V414_K1.0850.99
546_T565_I1.0820.99
83_Q87_S1.0790.99
441_L448_A1.0780.98
435_A458_N1.0770.98
86_V93_I1.0750.98
537_N544_H1.0720.98
531_E581_K1.0690.98
232_F309_V1.0680.98
532_L579_E1.0670.98
597_K601_I1.0650.98
572_L587_K1.0600.98
348_M352_K1.0590.98
39_I67_F1.0530.98
11_T198_G1.0530.98
319_P323_A1.0520.98
582_A585_E1.0520.98
282_N297_N1.0510.98
326_D414_K1.0500.98
71_R231_D1.0500.98
564_A594_V1.0480.98
589_Q592_A1.0480.98
281_V300_V1.0470.98
525_A528_K1.0430.98
158_G165_V1.0410.98
565_I595_S1.0380.98
12_T197_G1.0370.98
170_N393_D1.0330.98
70_K171_E1.0320.98
28_E130_Y1.0290.98
24_P373_I1.0280.98
42_Y105_V1.0260.98
571_A590_E1.0230.98
435_A460_D1.0210.98
265_A279_T1.0150.98
578_G583_A1.0130.98
14_S38_S1.0130.98
564_A567_S1.0130.98
542_L546_T1.0120.98
94_I109_K1.0100.98
66_L69_I1.0090.98
121_K125_K1.0090.98
583_A586_A1.0090.98
41_A49_L1.0040.98
200_F316_S1.0020.98
354_A361_P1.0000.98
26_V34_R0.9960.97
309_V312_L0.9940.97
232_F313_V0.9920.97
466_P469_M0.9880.97
564_A568_A0.9840.97
5_I138_A0.9830.97
235_R312_L0.9820.97
245_K253_R0.9810.97
535_T581_K0.9790.97
85_D226_H0.9780.97
117_A160_I0.9770.97
235_R238_N0.9770.97
425_V491_K0.9760.97
280_D299_K0.9760.97
564_A597_K0.9760.97
563_T566_E0.9740.97
9_L116_S0.9730.97
265_A272_E0.9680.97
172_P201_D0.9670.97
329_L333_D0.9650.97
321_K331_V0.9640.97
19_M24_P0.9630.97
398_S444_E0.9600.97
73_I154_T0.9510.97
557_L562_K0.9490.97
261_R284_P0.9450.97
240_L300_V0.9450.97
234_S263_K0.9440.97
549_Q553_A0.9440.97
547_R569_L0.9440.97
28_E34_R0.9420.96
86_V92_K0.9400.96
574_T578_G0.9390.96
558_P601_I0.9360.96
428_T468_G0.9350.96
148_D152_Q0.9330.96
492_N603_Q0.9290.96
43_T47_E0.9270.96
234_S237_I0.9270.96
170_N173_T0.9270.96
102_W111_A0.9250.96
320_L356_F0.9240.96
404_M429_A0.9220.96
479_D485_H0.9150.96
560_D564_A0.9140.96
546_T569_L0.9120.96
542_L588_M0.9110.96
171_E201_D0.9080.96
151_R170_N0.9080.96
17_A26_V0.9070.96
309_V348_M0.9050.96
596_Q600_E0.9040.96
241_V262_L0.9030.96
532_L535_T0.8980.95
593_Q596_Q0.8970.95
300_V305_L0.8960.95
575_A583_A0.8930.95
540_D544_H0.8920.95
243_E296_M0.8920.95
244_F296_M0.8910.95
465_A490_D0.8890.95
243_E247_D0.8890.95
189_T335_D0.8890.95
553_A565_I0.8890.95
110_M118_E0.8890.95
236_L239_Y0.8870.95
563_T574_T0.8840.95
251_D254_N0.8830.95
205_I218_V0.8830.95
42_Y115_I0.8820.95
542_L592_A0.8820.95
571_A575_A0.8790.95
191_A357_F0.8780.95
575_A584_I0.8740.95
147_N150_Q0.8720.95
335_D359_K0.8720.95
240_L296_M0.8720.95
431_D467_R0.8690.94
64_N105_V0.8690.94
550_V569_L0.8690.94
421_K477_D0.8680.94
575_A578_G0.8670.94
536_R579_E0.8650.94
565_I594_V0.8630.94
125_K128_E0.8590.94
535_T538_Q0.8580.94
553_A557_L0.8570.94
274_S347_P0.8550.94
314_N352_K0.8530.94
533_V536_R0.8530.94
317_I320_L0.8510.94
578_G584_I0.8500.94
261_R265_A0.8490.94
48_T121_K0.8480.94
84_R87_S0.8480.94
69_I73_I0.8470.94
539_G584_I0.8470.94
593_Q597_K0.8460.94
380_G386_V0.8450.94
222_N326_D0.8440.94
362_R370_A0.8420.94
237_I262_L0.8410.93
255_D258_A0.8400.93
4_I383_T0.8380.93
434_S440_V0.8380.93
241_V259_M0.8370.93
34_R366_N0.8330.93
140_I165_V0.8300.93
44_Q106_K0.8300.93
84_R88_I0.8290.93
39_I55_K0.8270.93
41_A61_N0.8260.93
220_A327_A0.8250.93
215_T390_L0.8250.93
126_T129_D0.8220.93
567_S570_T0.8190.93
8_D11_T0.8180.93
244_F248_Q0.8150.92
159_R516_V0.8140.92
536_R540_D0.8130.92
560_D563_T0.8100.92
440_V443_G0.8100.92
5_I135_V0.8100.92
445_R526_D0.8090.92
70_K198_G0.8090.92
314_N317_I0.8080.92
331_V356_F0.8070.92
543_L576_L0.8050.92
551_E554_G0.8020.92
172_P199_T0.7990.92
513_Q516_V0.7980.92
599_M602_A0.7970.92
188_R335_D0.7970.92
177_L389_V0.7950.91
4_I137_E0.7950.91
390_L480_A0.7950.91
572_L584_I0.7930.91
142_V170_N0.7920.91
144_A172_P0.7910.91
102_W109_K0.7910.91
61_N65_T0.7900.91
17_A24_P0.7900.91
144_A201_D0.7900.91
18_I131_L0.7890.91
590_E594_V0.7890.91
550_V566_E0.7880.91
14_S119_V0.7860.91
157_A161_A0.7860.91
428_T433_Q0.7840.91
105_V108_Q0.7840.91
237_I259_M0.7830.91
556_K605_Q0.7830.91
428_T431_D0.7810.91
6_G372_A0.7800.91
202_I323_A0.7790.91
29_N126_T0.7790.91
538_Q592_A0.7790.91
208_D215_T0.7780.91
72_L85_D0.7750.90
108_Q114_Q0.7750.90
198_G201_D0.7730.90
532_L536_R0.7730.90
425_V471_Q0.7720.90
575_A579_E0.7720.90
96_A100_D0.7710.90
324_L334_I0.7680.90
446_K530_E0.7680.90
592_A595_S0.7660.90
253_R259_M0.7660.90
590_E593_Q0.7650.90
540_D576_L0.7640.90
154_T199_T0.7590.89
531_E585_E0.7560.89
5_I127_A0.7550.89
599_M603_Q0.7530.89
222_N225_T0.7520.89
195_L312_L0.7510.89
287_T294_K0.7490.89
441_L456_Q0.7470.89
378_Q381_V0.7450.89
534_Q538_Q0.7440.88
538_Q543_L0.7430.88
465_A470_P0.7420.88
373_I377_V0.7410.88
94_I102_W0.7400.88
86_V89_M0.7390.88
72_L89_M0.7380.88
152_Q155_K0.7370.88
30_A122_K0.7370.88
72_L77_F0.7350.88
189_T334_I0.7350.88
193_Y317_I0.7350.88
320_L357_F0.7320.88
306_E348_M0.7300.88
402_E406_G0.7260.87
600_E603_Q0.7260.87
73_I116_S0.7250.87
73_I153_A0.7220.87
382_L480_A0.7210.87
548_K552_E0.7200.87
31_E52_Q0.7200.87
531_E534_Q0.7200.87
300_V304_K0.7190.87
120_L154_T0.7190.87
306_E309_V0.7160.87
239_Y281_V0.7160.87
399_L476_F0.7160.87
77_F86_V0.7160.87
507_L515_M0.7150.86
306_E346_M0.7140.86
436_V472_I0.7130.86
565_I591_L0.7070.86
5_I379_G0.7060.86
154_T172_P0.7060.86
320_L353_V0.7060.86
559_A570_T0.7050.86
36_T126_T0.7030.86
204_I327_A0.7020.85
352_K356_F0.7010.85
490_D493_S0.7010.85
553_A601_I0.7010.85
443_G451_N0.6990.85
455_G501_I0.6950.85
465_A469_M0.6930.85
6_G10_G0.6930.85
96_A99_G0.6910.85
141_T371_V0.6910.85
166_K379_G0.6900.84
457_F499_I0.6890.84
195_L343_Q0.6870.84
478_I484_L0.6860.84
140_I154_T0.6840.84
431_D468_G0.6840.84
111_A119_V0.6820.84
305_L312_L0.6810.84
38_S70_K0.6800.84
226_H320_L0.6800.84
559_A562_K0.6790.83
200_F227_L0.6780.83
427_S470_P0.6770.83
244_F286_I0.6770.83
142_V168_I0.6760.83
77_F95_A0.6750.83
139_V379_G0.6750.83
167_R378_Q0.6720.83
339_L353_V0.6720.83
432_N596_Q0.6720.83
43_T49_L0.6720.83
402_E405_G0.6720.83
122_K125_K0.6710.83
147_N225_T0.6700.83
261_R283_L0.6700.83
570_T573_E0.6700.83
581_K584_I0.6700.83
549_Q565_I0.6700.83
190_I336_D0.6690.83
394_V415_N0.6670.82
561_D598_L0.6660.82
184_G188_R0.6660.82
550_V553_A0.6650.82
279_T300_V0.6650.82
141_T169_I0.6640.82
175_A340_V0.6640.82
237_I241_V0.6610.82
224_D318_E0.6610.82
124_K138_A0.6600.82
100_D113_P0.6600.82
232_F343_Q0.6590.82
339_L363_K0.6580.82
563_T571_A0.6550.81
477_D485_H0.6550.81
286_I296_M0.6530.81
184_G362_R0.6530.81
570_T577_K0.6520.81
127_A131_L0.6520.81
244_F252_L0.6500.81
537_N541_H0.6500.81
235_R308_L0.6500.81
528_K531_E0.6480.81
414_K516_V0.6480.81
381_V384_G0.6480.81
260_Q264_E0.6480.81
248_Q252_L0.6470.80
261_R286_I0.6470.80
556_K561_D0.6460.80
602_A605_Q0.6460.80
273_L279_T0.6440.80
156_D507_L0.6440.80
595_S598_L0.6440.80
11_T70_K0.6420.80
146_F154_T0.6400.80
457_F488_A0.6390.80
474_V486_V0.6390.80
598_L601_I0.6390.80
7_I10_G0.6390.80
461_G465_A0.6380.80
597_K604_Q0.6360.79
203_S230_E0.6360.79
528_K532_L0.6340.79
33_D271_I0.6340.79
403_T407_V0.6330.79
244_F287_T0.6320.79
66_L103_V0.6310.79
181_L338_I0.6290.79
186_G335_D0.6280.78
556_K602_A0.6280.78
195_L344_T0.6280.78
492_N602_A0.6270.78
579_E584_I0.6270.78
11_T199_T0.6260.78
324_L327_A0.6250.78
288_A294_K0.6250.78
596_Q603_Q0.6230.78
561_D565_I0.6230.78
502_K505_S0.6230.78
557_L561_D0.6220.78
532_L584_I0.6210.78
532_L576_L0.6210.78
585_E588_M0.6200.78
568_A587_K0.6200.78
339_L361_P0.6190.77
288_A292_G0.6180.77
154_T201_D0.6170.77
343_Q368_D0.6160.77
553_A556_K0.6140.77
268_K272_E0.6140.77
588_M591_L0.6130.77
285_Y295_H0.6130.77
110_M522_N0.6130.77
236_L241_V0.6120.77
7_I140_I0.6110.77
571_A574_T0.6110.77
314_N318_E0.6110.77
561_D568_A0.6110.77
265_A283_L0.6110.77
29_N34_R0.6110.77
592_A599_M0.6110.77
551_E566_E0.6100.76
302_R347_P0.6100.76
309_V343_Q0.6080.76
18_I130_Y0.6080.76
539_G588_M0.6070.76
138_A163_L0.6070.76
36_T122_K0.6070.76
561_D597_K0.6070.76
569_L573_E0.6060.76
52_Q271_I0.6060.76
57_Q65_T0.6060.76
553_A569_L0.6050.76
395_T399_L0.6050.76
179_Y370_A0.6030.76
521_A525_A0.6010.75
36_T123_M0.6000.75
427_S471_Q0.6000.75
154_T171_E0.6000.75
128_E135_V0.6000.75
72_L75_R0.6000.75
146_F150_Q0.6000.75
438_I474_V0.5990.75
73_I113_P0.5990.75
148_D483_I0.5990.75
314_N321_K0.5980.75
7_I138_A0.5970.75
528_K582_A0.5970.75
255_D288_A0.5970.75
546_T599_M0.5960.75
175_A371_V0.5960.75
274_S302_R0.5960.75
12_T372_A0.5950.75
397_L445_R0.5950.75
539_G576_L0.5950.75
440_V476_F0.5950.75
144_A198_G0.5940.75
175_A199_T0.5930.74
196_G341_G0.5930.74
553_A561_D0.5930.74
114_Q515_M0.5910.74
336_D364_D0.5900.74
224_D227_L0.5890.74
144_A199_T0.5890.74
199_T231_D0.5890.74
403_T424_Q0.5870.74
71_R223_G0.5870.74
114_Q160_I0.5860.74
580_D584_I0.5860.74
594_V597_K0.5860.74
48_T522_N0.5850.73
557_L598_L0.5850.73
428_T466_P0.5850.73
138_A165_V0.5850.73
20_D130_Y0.5840.73
155_K168_I0.5840.73
85_D89_M0.5830.73
426_F474_V0.5830.73
563_T590_E0.5820.73
239_Y242_E0.5810.73
463_N490_D0.5810.73
192_V338_I0.5800.73
280_D298_I0.5790.73
278_Q301_T0.5790.73
18_I27_L0.5790.73
542_L595_S0.5790.73
548_K551_E0.5790.73
510_D513_Q0.5780.73
395_T412_I0.5760.72
313_V349_V0.5760.72
272_E276_A0.5740.72
340_V370_A0.5740.72
328_G337_V0.5730.72
273_L347_P0.5730.72
315_R319_P0.5730.72
519_A522_N0.5720.72
365_V370_A0.5710.72
546_T592_A0.5710.72
277_Q302_R0.5710.72
16_V126_T0.5700.72
5_I437_T0.5700.72
457_F461_G0.5690.71
473_E489_K0.5680.71
572_L591_L0.5680.71
9_L368_D0.5670.71
401_I424_Q0.5670.71
399_L412_I0.5670.71
143_P146_F0.5670.71
197_G201_D0.5670.71
13_N68_A0.5670.71
563_T570_T0.5640.71
564_A601_I0.5630.71
538_Q541_H0.5630.71
529_F532_L0.5620.70
438_I457_F0.5620.70
70_K199_T0.5620.70
539_G544_H0.5620.70
398_S408_M0.5620.70
113_P153_A0.5620.70
268_K271_I0.5620.70
382_L390_L0.5610.70
190_I207_I0.5610.70
580_D586_A0.5610.70
401_I411_L0.5610.70
507_L511_E0.5610.70
4_I380_G0.5600.70
207_I216_F0.5600.70
541_H544_H0.5600.70
60_T257_L0.5600.70
331_V358_G0.5590.70
403_T426_F0.5590.70
75_R150_Q0.5590.70
70_K116_S0.5580.70
38_S198_G0.5570.70
411_L426_F0.5570.70
264_E268_K0.5570.70
564_A590_E0.5570.70
536_R596_Q0.5560.70
43_T46_G0.5560.70
559_A564_A0.5560.70
532_L581_K0.5550.70
571_A586_A0.5540.69
266_A281_V0.5540.69
222_N323_A0.5540.69
89_M93_I0.5540.69
22_T385_D0.5540.69
156_D160_I0.5530.69
598_L604_Q0.5530.69
136_T164_E0.5530.69
601_I605_Q0.5510.69
195_L316_S0.5510.69
281_V298_I0.5510.69
590_E595_S0.5500.69
544_H548_K0.5500.69
445_R450_D0.5500.69
545_S553_A0.5500.69
286_I295_H0.5480.69
59_V260_Q0.5470.68
473_E491_K0.5460.68
215_T392_L0.5460.68
184_G336_D0.5440.68
131_L135_V0.5430.68
25_R28_E0.5430.68
567_S574_T0.5410.68
55_K267_E0.5410.68
144_A223_G0.5410.68
276_A279_T0.5400.67
98_N101_A0.5390.67
147_N452_K0.5390.67
148_D170_N0.5390.67
540_D573_E0.5380.67
543_L591_L0.5380.67
74_G153_A0.5380.67
341_G374_G0.5380.67
316_S349_V0.5370.67
261_R285_Y0.5370.67
386_V389_V0.5370.67
17_A379_G0.5370.67
554_G558_P0.5370.67
487_S496_E0.5360.67
29_N32_G0.5350.67
475_T487_S0.5350.67
14_S199_T0.5350.67
438_I472_I0.5340.67
116_S120_L0.5340.67
518_D522_N0.5340.67
129_D363_K0.5340.67
538_Q544_H0.5330.66
170_N482_G0.5320.66
595_S602_A0.5320.66
137_E383_T0.5310.66
568_A576_L0.5310.66
444_E451_N0.5310.66
265_A281_V0.5300.66
73_I85_D0.5300.66
116_S199_T0.5300.66
592_A602_A0.5290.66
177_L378_Q0.5290.66
70_K371_V0.5270.66
514_K517_R0.5260.65
325_Q328_G0.5250.65
93_I101_A0.5250.65
187_N207_I0.5240.65
543_L588_M0.5240.65
193_Y200_F0.5230.65
70_K172_P0.5230.65
586_A596_Q0.5220.65
273_L302_R0.5220.65
191_A334_I0.5210.65
395_T398_S0.5210.65
260_Q338_I0.5200.65
142_V151_R0.5200.65
414_K444_E0.5190.64
546_T557_L0.5190.64
3_K140_I0.5190.64
133_E137_E0.5180.64
89_M103_V0.5180.64
11_T172_P0.5170.64
155_K481_D0.5170.64
549_Q595_S0.5170.64
96_A109_K0.5160.64
402_E441_L0.5160.64
585_E593_Q0.5160.64
413_A416_T0.5160.64
244_F294_K0.5160.64
259_M263_K0.5150.64
218_V393_D0.5150.64
121_K124_K0.5140.64
195_L349_V0.5140.64
151_R482_G0.5140.64
252_L258_A0.5130.64
198_G223_G0.5130.64
595_S600_E0.5110.63
559_A567_S0.5110.63
432_N466_P0.5110.63
555_D563_T0.5100.63
121_K523_A0.5090.63
412_I420_T0.5090.63
470_P490_D0.5090.63
551_E570_T0.5080.63
94_I100_D0.5080.63
529_F533_V0.5070.63
227_L231_D0.5070.63
345_R369_E0.5070.63
75_R78_Q0.5070.63
250_I294_K0.5060.62
329_L334_I0.5060.62
442_Q452_K0.5060.62
76_R100_D0.5050.62
173_T180_G0.5040.62
576_L581_K0.5040.62
511_E515_M0.5040.62
569_L595_S0.5030.62
408_M451_N0.5030.62
476_F484_L0.5020.62
399_L486_V0.5020.62
569_L572_L0.5010.62
561_D599_M0.5010.62
125_K334_I0.5000.62
316_S352_K0.5000.62
587_K594_V0.5000.62
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3d2fA 1 0.9436 100 0.153 Contact Map
4jneA 2 0.9404 100 0.175 Contact Map
4fl9A 1 0.8307 100 0.23 Contact Map
2v7yA 1 0.79 100 0.268 Contact Map
4rtfD 1 0.5455 100 0.282 Contact Map
3i33A 1 0.5815 100 0.475 Contact Map
4kboA 1 0.5862 100 0.478 Contact Map
4j8fA 2 0.8339 100 0.495 Contact Map
3qfuA 1 0.5846 100 0.532 Contact Map
4gniA 2 0.5768 100 0.532 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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