DNAK - ECOLI - GREMLIN Contacts

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DNAK - Chaperone protein DnaK

UniProt:	P0A6Y8	Sequences: MGKIIGIDLGTTNSCVAIMDGTTPRVLENAEGDRTTPSIIAYTQDGETLVGQPAKRQAVTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPFKIIAADNGDAWVEVKGQKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAALAYGLDKGTGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEVLATNGDTHLGGEDFDSRLINYLVEEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSAQQTDVNLPYITADATGPKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQDAGLSVSDIDDVILVGGQTRMPMVQKKVAEFFGKEPRKDVNPDEAVAIGAAVQGGVLTGDVKDVLLLDVTPLSLGIETMGGVMTTLIAKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRAADNKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLNEDEIQKMVRDAEANAEADRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADDKTAIESALTALETALKGEDKAAIEAKMQELAQVSQKLMEIAQQQHAQQQTAGADASANNAKDDDVVDAEFEEVKDKK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10241
Length:	638 (588)
Sequences:	6370 (2975)
Seq/√Len:	122.7

ECOLI - DNAK HSCA HSCC
BACSU - DNAK
HALSA - DNAK

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
137_E	164_E	5.237	1.00
224_D	315_R	4.941	1.00
235_R	311_D	4.556	1.00
236_L	300_V	3.676	1.00
354_A	360_E	3.640	1.00
193_Y	316_S	3.566	1.00
278_Q	299_K	3.528	1.00
68_A	230_E	3.425	1.00
351_K	355_E	3.379	1.00
204_I	323_A	3.173	1.00
243_E	304_K	3.105	1.00
398_S	410_T	3.001	1.00
580_D	583_A	2.964	1.00
29_N	36_T	2.939	1.00
241_V	253_R	2.842	1.00
547_R	573_E	2.839	1.00
509_E	513_Q	2.832	1.00
439_H	453_S	2.817	1.00
366_N	369_E	2.787	1.00
104_E	109_K	2.738	1.00
33_D	52_Q	2.706	1.00
437_T	458_N	2.679	1.00
409_T	426_F	2.634	1.00
240_L	298_I	2.564	1.00
137_E	166_K	2.533	1.00
220_A	323_A	2.529	1.00
410_T	413_A	2.521	1.00
350_Q	363_K	2.511	1.00
92_K	104_E	2.447	1.00
304_K	307_S	2.426	1.00
104_E	107_G	2.392	1.00
195_L	232_F	2.333	1.00
522_N	525_A	2.324	1.00
563_T	567_S	2.296	1.00
4_I	166_K	2.284	1.00
240_L	266_A	2.275	1.00
520_E	523_A	2.259	1.00
191_A	204_I	2.237	1.00
310_E	314_N	2.208	1.00
191_A	202_I	2.204	1.00
514_K	518_D	2.175	1.00
78_Q	95_A	2.174	1.00
124_K	128_E	2.171	1.00
343_Q	346_M	2.155	1.00
309_V	346_M	2.144	1.00
570_T	574_T	2.122	1.00
63_Q	92_K	2.119	1.00
313_V	348_M	2.112	1.00
317_I	356_F	2.108	1.00
489_K	496_E	2.091	1.00
400_G	408_M	2.076	1.00
243_E	246_K	2.069	1.00
539_G	572_L	2.055	1.00
234_S	238_N	2.050	1.00
561_D	601_I	2.048	1.00
280_D	297_N	2.041	1.00
69_I	103_V	2.036	1.00
352_K	355_E	2.024	1.00
554_G	562_K	2.017	1.00
232_F	312_L	2.009	1.00
441_L	453_S	2.003	1.00
125_K	129_D	1.998	1.00
318_E	322_V	1.964	1.00
558_P	561_D	1.964	1.00
517_R	521_A	1.949	1.00
5_I	16_V	1.941	1.00
48_T	118_E	1.939	1.00
20_D	25_R	1.937	1.00
600_E	604_Q	1.913	1.00
527_R	531_E	1.912	1.00
237_I	263_K	1.910	1.00
546_T	595_S	1.894	1.00
524_E	528_K	1.860	1.00
574_T	577_K	1.852	1.00
437_T	456_Q	1.829	1.00
4_I	379_G	1.826	1.00
585_E	589_Q	1.824	1.00
17_A	376_A	1.816	1.00
587_K	590_E	1.809	1.00
566_E	570_T	1.791	1.00
305_L	343_Q	1.786	1.00
517_R	520_E	1.784	1.00
571_A	587_K	1.764	1.00
305_L	346_M	1.755	1.00
589_Q	593_Q	1.752	1.00
141_T	375_A	1.722	1.00
63_Q	256_P	1.711	1.00
152_Q	156_D	1.707	1.00
597_K	600_E	1.699	1.00
317_I	321_K	1.691	1.00
269_A	281_V	1.691	1.00
330_S	333_D	1.676	1.00
345_R	368_D	1.665	1.00
306_E	351_K	1.658	1.00
301_T	304_K	1.657	1.00
513_Q	517_R	1.656	1.00
559_A	563_T	1.651	1.00
188_R	336_D	1.649	1.00
83_Q	86_V	1.645	1.00
267_E	271_I	1.645	1.00
269_A	279_T	1.637	1.00
336_D	362_R	1.633	1.00
318_E	321_K	1.631	1.00
15_C	35_T	1.630	1.00
159_R	164_E	1.628	1.00
265_A	269_A	1.620	1.00
110_M	115_I	1.613	1.00
581_K	585_E	1.612	1.00
96_A	102_W	1.598	1.00
583_A	587_K	1.592	1.00
439_H	456_Q	1.589	1.00
240_L	281_V	1.588	1.00
567_S	571_A	1.568	1.00
568_A	590_E	1.567	1.00
562_K	566_E	1.566	1.00
118_E	121_K	1.560	1.00
423_S	473_E	1.555	1.00
34_R	369_E	1.554	1.00
321_K	356_F	1.551	1.00
236_L	266_A	1.550	1.00
592_A	596_Q	1.544	1.00
248_Q	294_K	1.541	1.00
309_V	313_V	1.538	1.00
159_R	509_E	1.538	1.00
321_K	325_Q	1.532	1.00
64_N	106_K	1.523	1.00
392_L	417_T	1.517	1.00
403_T	409_T	1.508	1.00
122_K	126_T	1.504	1.00
307_S	310_E	1.495	1.00
204_I	334_I	1.495	1.00
586_A	590_E	1.492	1.00
242_E	253_R	1.489	1.00
14_S	123_M	1.487	1.00
543_L	573_E	1.484	1.00
15_C	26_V	1.482	1.00
42_Y	118_E	1.477	1.00
240_L	262_L	1.475	1.00
447_R	533_V	1.471	1.00
67_F	90_P	1.466	1.00
471_Q	491_K	1.457	1.00
123_M	126_T	1.437	1.00
568_A	571_A	1.432	1.00
239_Y	304_K	1.427	1.00
573_E	577_K	1.402	1.00
140_I	158_G	1.402	1.00
113_P	156_D	1.402	1.00
252_L	286_I	1.400	1.00
395_T	478_I	1.399	1.00
27_L	130_Y	1.390	1.00
116_S	154_T	1.387	1.00
423_S	475_T	1.381	1.00
304_K	308_L	1.379	1.00
41_A	57_Q	1.378	1.00
235_R	309_V	1.368	1.00
511_E	514_K	1.365	1.00
322_V	326_D	1.365	1.00
410_T	446_K	1.363	1.00
204_I	329_L	1.363	1.00
561_D	564_A	1.355	1.00
543_L	569_L	1.346	1.00
518_D	521_A	1.345	1.00
317_I	352_K	1.343	1.00
453_S	456_Q	1.342	1.00
195_L	200_F	1.342	1.00
158_G	168_I	1.335	1.00
78_Q	99_G	1.334	1.00
156_D	159_R	1.333	1.00
26_V	373_I	1.329	1.00
402_E	439_H	1.326	1.00
239_Y	308_L	1.323	1.00
538_Q	588_M	1.322	1.00
409_T	424_Q	1.322	1.00
324_L	331_V	1.322	1.00
69_I	119_V	1.317	1.00
61_N	64_N	1.316	1.00
17_A	372_A	1.312	1.00
353_V	361_P	1.310	1.00
447_R	450_D	1.307	1.00
586_A	589_Q	1.305	1.00
535_T	585_E	1.304	1.00
582_A	586_A	1.299	1.00
351_K	354_A	1.299	1.00
588_M	592_A	1.295	1.00
189_T	206_E	1.295	1.00
272_E	279_T	1.291	1.00
9_L	154_T	1.291	1.00
95_A	99_G	1.291	1.00
9_L	120_L	1.290	1.00
114_Q	118_E	1.289	1.00
238_N	253_R	1.288	1.00
66_L	115_I	1.286	1.00
416_T	420_T	1.281	1.00
69_I	116_S	1.281	1.00
245_K	251_D	1.280	1.00
595_S	599_M	1.271	1.00
535_T	588_M	1.270	1.00
66_L	105_V	1.269	1.00
242_E	245_K	1.264	1.00
568_A	572_L	1.259	1.00
322_V	325_Q	1.257	1.00
232_F	305_L	1.253	1.00
243_E	298_I	1.252	1.00
3_K	133_E	1.249	0.99
523_A	527_R	1.247	0.99
16_V	123_M	1.245	0.99
568_A	594_V	1.245	0.99
559_A	566_E	1.243	0.99
57_Q	61_N	1.241	0.99
222_N	319_P	1.236	0.99
508_N	511_E	1.235	0.99
575_A	587_K	1.231	0.99
19_M	380_G	1.230	0.99
238_N	242_E	1.219	0.99
265_A	268_K	1.215	0.99
310_E	348_M	1.213	0.99
77_F	83_Q	1.210	0.99
601_I	604_Q	1.210	0.99
313_V	352_K	1.209	0.99
72_L	103_V	1.207	0.99
189_T	329_L	1.206	0.99
191_A	320_L	1.205	0.99
239_Y	298_I	1.199	0.99
232_F	346_M	1.194	0.99
30_A	126_T	1.193	0.99
69_I	115_I	1.192	0.99
239_Y	243_E	1.192	0.99
543_L	572_L	1.190	0.99
536_R	576_L	1.189	0.99
515_M	518_D	1.187	0.99
408_M	441_L	1.185	0.99
425_V	473_E	1.179	0.99
124_K	163_L	1.174	0.99
222_N	322_V	1.173	0.99
42_Y	110_M	1.170	0.99
166_K	382_L	1.170	0.99
524_E	527_R	1.168	0.99
324_L	329_L	1.167	0.99
40_I	115_I	1.162	0.99
547_R	551_E	1.161	0.99
545_S	549_Q	1.161	0.99
530_E	534_Q	1.156	0.99
206_E	219_L	1.155	0.99
323_A	327_A	1.153	0.99
239_Y	300_V	1.150	0.99
219_L	329_L	1.150	0.99
269_A	300_V	1.136	0.99
189_T	219_L	1.133	0.99
155_K	483_I	1.131	0.99
550_V	562_K	1.119	0.99
348_M	351_K	1.117	0.99
463_N	492_N	1.116	0.99
302_R	306_E	1.113	0.99
553_A	602_A	1.104	0.99
94_I	104_E	1.099	0.99
237_I	266_A	1.097	0.99
128_E	134_P	1.093	0.99
596_Q	599_M	1.092	0.99
421_K	475_T	1.086	0.99
322_V	414_K	1.085	0.99
546_T	565_I	1.082	0.99
83_Q	87_S	1.079	0.99
441_L	448_A	1.078	0.98
435_A	458_N	1.077	0.98
86_V	93_I	1.075	0.98
537_N	544_H	1.072	0.98
531_E	581_K	1.069	0.98
232_F	309_V	1.068	0.98
532_L	579_E	1.067	0.98
597_K	601_I	1.065	0.98
572_L	587_K	1.060	0.98
348_M	352_K	1.059	0.98
39_I	67_F	1.053	0.98
11_T	198_G	1.053	0.98
319_P	323_A	1.052	0.98
582_A	585_E	1.052	0.98
282_N	297_N	1.051	0.98
326_D	414_K	1.050	0.98
71_R	231_D	1.050	0.98
564_A	594_V	1.048	0.98
589_Q	592_A	1.048	0.98
281_V	300_V	1.047	0.98
525_A	528_K	1.043	0.98
158_G	165_V	1.041	0.98
565_I	595_S	1.038	0.98
12_T	197_G	1.037	0.98
170_N	393_D	1.033	0.98
70_K	171_E	1.032	0.98
28_E	130_Y	1.029	0.98
24_P	373_I	1.028	0.98
42_Y	105_V	1.026	0.98
571_A	590_E	1.023	0.98
435_A	460_D	1.021	0.98
265_A	279_T	1.015	0.98
578_G	583_A	1.013	0.98
14_S	38_S	1.013	0.98
564_A	567_S	1.013	0.98
542_L	546_T	1.012	0.98
94_I	109_K	1.010	0.98
66_L	69_I	1.009	0.98
121_K	125_K	1.009	0.98
583_A	586_A	1.009	0.98
41_A	49_L	1.004	0.98
200_F	316_S	1.002	0.98
354_A	361_P	1.000	0.98
26_V	34_R	0.996	0.97
309_V	312_L	0.994	0.97
232_F	313_V	0.992	0.97
466_P	469_M	0.988	0.97
564_A	568_A	0.984	0.97
5_I	138_A	0.983	0.97
235_R	312_L	0.982	0.97
245_K	253_R	0.981	0.97
535_T	581_K	0.979	0.97
85_D	226_H	0.978	0.97
117_A	160_I	0.977	0.97
235_R	238_N	0.977	0.97
425_V	491_K	0.976	0.97
280_D	299_K	0.976	0.97
564_A	597_K	0.976	0.97
563_T	566_E	0.974	0.97
9_L	116_S	0.973	0.97
265_A	272_E	0.968	0.97
172_P	201_D	0.967	0.97
329_L	333_D	0.965	0.97
321_K	331_V	0.964	0.97
19_M	24_P	0.963	0.97
398_S	444_E	0.960	0.97
73_I	154_T	0.951	0.97
557_L	562_K	0.949	0.97
261_R	284_P	0.945	0.97
240_L	300_V	0.945	0.97
234_S	263_K	0.944	0.97
549_Q	553_A	0.944	0.97
547_R	569_L	0.944	0.97
28_E	34_R	0.942	0.96
86_V	92_K	0.940	0.96
574_T	578_G	0.939	0.96
558_P	601_I	0.936	0.96
428_T	468_G	0.935	0.96
148_D	152_Q	0.933	0.96
492_N	603_Q	0.929	0.96
43_T	47_E	0.927	0.96
234_S	237_I	0.927	0.96
170_N	173_T	0.927	0.96
102_W	111_A	0.925	0.96
320_L	356_F	0.924	0.96
404_M	429_A	0.922	0.96
479_D	485_H	0.915	0.96
560_D	564_A	0.914	0.96
546_T	569_L	0.912	0.96
542_L	588_M	0.911	0.96
171_E	201_D	0.908	0.96
151_R	170_N	0.908	0.96
17_A	26_V	0.907	0.96
309_V	348_M	0.905	0.96
596_Q	600_E	0.904	0.96
241_V	262_L	0.903	0.96
532_L	535_T	0.898	0.95
593_Q	596_Q	0.897	0.95
300_V	305_L	0.896	0.95
575_A	583_A	0.893	0.95
540_D	544_H	0.892	0.95
243_E	296_M	0.892	0.95
244_F	296_M	0.891	0.95
465_A	490_D	0.889	0.95
243_E	247_D	0.889	0.95
189_T	335_D	0.889	0.95
553_A	565_I	0.889	0.95
110_M	118_E	0.889	0.95
236_L	239_Y	0.887	0.95
563_T	574_T	0.884	0.95
251_D	254_N	0.883	0.95
205_I	218_V	0.883	0.95
42_Y	115_I	0.882	0.95
542_L	592_A	0.882	0.95
571_A	575_A	0.879	0.95
191_A	357_F	0.878	0.95
575_A	584_I	0.874	0.95
147_N	150_Q	0.872	0.95
335_D	359_K	0.872	0.95
240_L	296_M	0.872	0.95
431_D	467_R	0.869	0.94
64_N	105_V	0.869	0.94
550_V	569_L	0.869	0.94
421_K	477_D	0.868	0.94
575_A	578_G	0.867	0.94
536_R	579_E	0.865	0.94
565_I	594_V	0.863	0.94
125_K	128_E	0.859	0.94
535_T	538_Q	0.858	0.94
553_A	557_L	0.857	0.94
274_S	347_P	0.855	0.94
314_N	352_K	0.853	0.94
533_V	536_R	0.853	0.94
317_I	320_L	0.851	0.94
578_G	584_I	0.850	0.94
261_R	265_A	0.849	0.94
48_T	121_K	0.848	0.94
84_R	87_S	0.848	0.94
69_I	73_I	0.847	0.94
539_G	584_I	0.847	0.94
593_Q	597_K	0.846	0.94
380_G	386_V	0.845	0.94
222_N	326_D	0.844	0.94
362_R	370_A	0.842	0.94
237_I	262_L	0.841	0.93
255_D	258_A	0.840	0.93
4_I	383_T	0.838	0.93
434_S	440_V	0.838	0.93
241_V	259_M	0.837	0.93
34_R	366_N	0.833	0.93
140_I	165_V	0.830	0.93
44_Q	106_K	0.830	0.93
84_R	88_I	0.829	0.93
39_I	55_K	0.827	0.93
41_A	61_N	0.826	0.93
220_A	327_A	0.825	0.93
215_T	390_L	0.825	0.93
126_T	129_D	0.822	0.93
567_S	570_T	0.819	0.93
8_D	11_T	0.818	0.93
244_F	248_Q	0.815	0.92
159_R	516_V	0.814	0.92
536_R	540_D	0.813	0.92
560_D	563_T	0.810	0.92
440_V	443_G	0.810	0.92
5_I	135_V	0.810	0.92
445_R	526_D	0.809	0.92
70_K	198_G	0.809	0.92
314_N	317_I	0.808	0.92
331_V	356_F	0.807	0.92
543_L	576_L	0.805	0.92
551_E	554_G	0.802	0.92
172_P	199_T	0.799	0.92
513_Q	516_V	0.798	0.92
599_M	602_A	0.797	0.92
188_R	335_D	0.797	0.92
177_L	389_V	0.795	0.91
4_I	137_E	0.795	0.91
390_L	480_A	0.795	0.91
572_L	584_I	0.793	0.91
142_V	170_N	0.792	0.91
144_A	172_P	0.791	0.91
102_W	109_K	0.791	0.91
61_N	65_T	0.790	0.91
17_A	24_P	0.790	0.91
144_A	201_D	0.790	0.91
18_I	131_L	0.789	0.91
590_E	594_V	0.789	0.91
550_V	566_E	0.788	0.91
14_S	119_V	0.786	0.91
157_A	161_A	0.786	0.91
428_T	433_Q	0.784	0.91
105_V	108_Q	0.784	0.91
237_I	259_M	0.783	0.91
556_K	605_Q	0.783	0.91
428_T	431_D	0.781	0.91
6_G	372_A	0.780	0.91
202_I	323_A	0.779	0.91
29_N	126_T	0.779	0.91
538_Q	592_A	0.779	0.91
208_D	215_T	0.778	0.91
72_L	85_D	0.775	0.90
108_Q	114_Q	0.775	0.90
198_G	201_D	0.773	0.90
532_L	536_R	0.773	0.90
425_V	471_Q	0.772	0.90
575_A	579_E	0.772	0.90
96_A	100_D	0.771	0.90
324_L	334_I	0.768	0.90
446_K	530_E	0.768	0.90
592_A	595_S	0.766	0.90
253_R	259_M	0.766	0.90
590_E	593_Q	0.765	0.90
540_D	576_L	0.764	0.90
154_T	199_T	0.759	0.89
531_E	585_E	0.756	0.89
5_I	127_A	0.755	0.89
599_M	603_Q	0.753	0.89
222_N	225_T	0.752	0.89
195_L	312_L	0.751	0.89
287_T	294_K	0.749	0.89
441_L	456_Q	0.747	0.89
378_Q	381_V	0.745	0.89
534_Q	538_Q	0.744	0.88
538_Q	543_L	0.743	0.88
465_A	470_P	0.742	0.88
373_I	377_V	0.741	0.88
94_I	102_W	0.740	0.88
86_V	89_M	0.739	0.88
72_L	89_M	0.738	0.88
152_Q	155_K	0.737	0.88
30_A	122_K	0.737	0.88
72_L	77_F	0.735	0.88
189_T	334_I	0.735	0.88
193_Y	317_I	0.735	0.88
320_L	357_F	0.732	0.88
306_E	348_M	0.730	0.88
402_E	406_G	0.726	0.87
600_E	603_Q	0.726	0.87
73_I	116_S	0.725	0.87
73_I	153_A	0.722	0.87
382_L	480_A	0.721	0.87
548_K	552_E	0.720	0.87
31_E	52_Q	0.720	0.87
531_E	534_Q	0.720	0.87
300_V	304_K	0.719	0.87
120_L	154_T	0.719	0.87
306_E	309_V	0.716	0.87
239_Y	281_V	0.716	0.87
399_L	476_F	0.716	0.87
77_F	86_V	0.716	0.87
507_L	515_M	0.715	0.86
306_E	346_M	0.714	0.86
436_V	472_I	0.713	0.86
565_I	591_L	0.707	0.86
5_I	379_G	0.706	0.86
154_T	172_P	0.706	0.86
320_L	353_V	0.706	0.86
559_A	570_T	0.705	0.86
36_T	126_T	0.703	0.86
204_I	327_A	0.702	0.85
352_K	356_F	0.701	0.85
490_D	493_S	0.701	0.85
553_A	601_I	0.701	0.85
443_G	451_N	0.699	0.85
455_G	501_I	0.695	0.85
465_A	469_M	0.693	0.85
6_G	10_G	0.693	0.85
96_A	99_G	0.691	0.85
141_T	371_V	0.691	0.85
166_K	379_G	0.690	0.84
457_F	499_I	0.689	0.84
195_L	343_Q	0.687	0.84
478_I	484_L	0.686	0.84
140_I	154_T	0.684	0.84
431_D	468_G	0.684	0.84
111_A	119_V	0.682	0.84
305_L	312_L	0.681	0.84
38_S	70_K	0.680	0.84
226_H	320_L	0.680	0.84
559_A	562_K	0.679	0.83
200_F	227_L	0.678	0.83
427_S	470_P	0.677	0.83
244_F	286_I	0.677	0.83
142_V	168_I	0.676	0.83
77_F	95_A	0.675	0.83
139_V	379_G	0.675	0.83
167_R	378_Q	0.672	0.83
339_L	353_V	0.672	0.83
432_N	596_Q	0.672	0.83
43_T	49_L	0.672	0.83
402_E	405_G	0.672	0.83
122_K	125_K	0.671	0.83
147_N	225_T	0.670	0.83
261_R	283_L	0.670	0.83
570_T	573_E	0.670	0.83
581_K	584_I	0.670	0.83
549_Q	565_I	0.670	0.83
190_I	336_D	0.669	0.83
394_V	415_N	0.667	0.82
561_D	598_L	0.666	0.82
184_G	188_R	0.666	0.82
550_V	553_A	0.665	0.82
279_T	300_V	0.665	0.82
141_T	169_I	0.664	0.82
175_A	340_V	0.664	0.82
237_I	241_V	0.661	0.82
224_D	318_E	0.661	0.82
124_K	138_A	0.660	0.82
100_D	113_P	0.660	0.82
232_F	343_Q	0.659	0.82
339_L	363_K	0.658	0.82
563_T	571_A	0.655	0.81
477_D	485_H	0.655	0.81
286_I	296_M	0.653	0.81
184_G	362_R	0.653	0.81
570_T	577_K	0.652	0.81
127_A	131_L	0.652	0.81
244_F	252_L	0.650	0.81
537_N	541_H	0.650	0.81
235_R	308_L	0.650	0.81
528_K	531_E	0.648	0.81
414_K	516_V	0.648	0.81
381_V	384_G	0.648	0.81
260_Q	264_E	0.648	0.81
248_Q	252_L	0.647	0.80
261_R	286_I	0.647	0.80
556_K	561_D	0.646	0.80
602_A	605_Q	0.646	0.80
273_L	279_T	0.644	0.80
156_D	507_L	0.644	0.80
595_S	598_L	0.644	0.80
11_T	70_K	0.642	0.80
146_F	154_T	0.640	0.80
457_F	488_A	0.639	0.80
474_V	486_V	0.639	0.80
598_L	601_I	0.639	0.80
7_I	10_G	0.639	0.80
461_G	465_A	0.638	0.80
597_K	604_Q	0.636	0.79
203_S	230_E	0.636	0.79
528_K	532_L	0.634	0.79
33_D	271_I	0.634	0.79
403_T	407_V	0.633	0.79
244_F	287_T	0.632	0.79
66_L	103_V	0.631	0.79
181_L	338_I	0.629	0.79
186_G	335_D	0.628	0.78
556_K	602_A	0.628	0.78
195_L	344_T	0.628	0.78
492_N	602_A	0.627	0.78
579_E	584_I	0.627	0.78
11_T	199_T	0.626	0.78
324_L	327_A	0.625	0.78
288_A	294_K	0.625	0.78
596_Q	603_Q	0.623	0.78
561_D	565_I	0.623	0.78
502_K	505_S	0.623	0.78
557_L	561_D	0.622	0.78
532_L	584_I	0.621	0.78
532_L	576_L	0.621	0.78
585_E	588_M	0.620	0.78
568_A	587_K	0.620	0.78
339_L	361_P	0.619	0.77
288_A	292_G	0.618	0.77
154_T	201_D	0.617	0.77
343_Q	368_D	0.616	0.77
553_A	556_K	0.614	0.77
268_K	272_E	0.614	0.77
588_M	591_L	0.613	0.77
285_Y	295_H	0.613	0.77
110_M	522_N	0.613	0.77
236_L	241_V	0.612	0.77
7_I	140_I	0.611	0.77
571_A	574_T	0.611	0.77
314_N	318_E	0.611	0.77
561_D	568_A	0.611	0.77
265_A	283_L	0.611	0.77
29_N	34_R	0.611	0.77
592_A	599_M	0.611	0.77
551_E	566_E	0.610	0.76
302_R	347_P	0.610	0.76
309_V	343_Q	0.608	0.76
18_I	130_Y	0.608	0.76
539_G	588_M	0.607	0.76
138_A	163_L	0.607	0.76
36_T	122_K	0.607	0.76
561_D	597_K	0.607	0.76
569_L	573_E	0.606	0.76
52_Q	271_I	0.606	0.76
57_Q	65_T	0.606	0.76
553_A	569_L	0.605	0.76
395_T	399_L	0.605	0.76
179_Y	370_A	0.603	0.76
521_A	525_A	0.601	0.75
36_T	123_M	0.600	0.75
427_S	471_Q	0.600	0.75
154_T	171_E	0.600	0.75
128_E	135_V	0.600	0.75
72_L	75_R	0.600	0.75
146_F	150_Q	0.600	0.75
438_I	474_V	0.599	0.75
73_I	113_P	0.599	0.75
148_D	483_I	0.599	0.75
314_N	321_K	0.598	0.75
7_I	138_A	0.597	0.75
528_K	582_A	0.597	0.75
255_D	288_A	0.597	0.75
546_T	599_M	0.596	0.75
175_A	371_V	0.596	0.75
274_S	302_R	0.596	0.75
12_T	372_A	0.595	0.75
397_L	445_R	0.595	0.75
539_G	576_L	0.595	0.75
440_V	476_F	0.595	0.75
144_A	198_G	0.594	0.75
175_A	199_T	0.593	0.74
196_G	341_G	0.593	0.74
553_A	561_D	0.593	0.74
114_Q	515_M	0.591	0.74
336_D	364_D	0.590	0.74
224_D	227_L	0.589	0.74
144_A	199_T	0.589	0.74
199_T	231_D	0.589	0.74
403_T	424_Q	0.587	0.74
71_R	223_G	0.587	0.74
114_Q	160_I	0.586	0.74
580_D	584_I	0.586	0.74
594_V	597_K	0.586	0.74
48_T	522_N	0.585	0.73
557_L	598_L	0.585	0.73
428_T	466_P	0.585	0.73
138_A	165_V	0.585	0.73
20_D	130_Y	0.584	0.73
155_K	168_I	0.584	0.73
85_D	89_M	0.583	0.73
426_F	474_V	0.583	0.73
563_T	590_E	0.582	0.73
239_Y	242_E	0.581	0.73
463_N	490_D	0.581	0.73
192_V	338_I	0.580	0.73
280_D	298_I	0.579	0.73
278_Q	301_T	0.579	0.73
18_I	27_L	0.579	0.73
542_L	595_S	0.579	0.73
548_K	551_E	0.579	0.73
510_D	513_Q	0.578	0.73
395_T	412_I	0.576	0.72
313_V	349_V	0.576	0.72
272_E	276_A	0.574	0.72
340_V	370_A	0.574	0.72
328_G	337_V	0.573	0.72
273_L	347_P	0.573	0.72
315_R	319_P	0.573	0.72
519_A	522_N	0.572	0.72
365_V	370_A	0.571	0.72
546_T	592_A	0.571	0.72
277_Q	302_R	0.571	0.72
16_V	126_T	0.570	0.72
5_I	437_T	0.570	0.72
457_F	461_G	0.569	0.71
473_E	489_K	0.568	0.71
572_L	591_L	0.568	0.71
9_L	368_D	0.567	0.71
401_I	424_Q	0.567	0.71
399_L	412_I	0.567	0.71
143_P	146_F	0.567	0.71
197_G	201_D	0.567	0.71
13_N	68_A	0.567	0.71
563_T	570_T	0.564	0.71
564_A	601_I	0.563	0.71
538_Q	541_H	0.563	0.71
529_F	532_L	0.562	0.70
438_I	457_F	0.562	0.70
70_K	199_T	0.562	0.70
539_G	544_H	0.562	0.70
398_S	408_M	0.562	0.70
113_P	153_A	0.562	0.70
268_K	271_I	0.562	0.70
382_L	390_L	0.561	0.70
190_I	207_I	0.561	0.70
580_D	586_A	0.561	0.70
401_I	411_L	0.561	0.70
507_L	511_E	0.561	0.70
4_I	380_G	0.560	0.70
207_I	216_F	0.560	0.70
541_H	544_H	0.560	0.70
60_T	257_L	0.560	0.70
331_V	358_G	0.559	0.70
403_T	426_F	0.559	0.70
75_R	150_Q	0.559	0.70
70_K	116_S	0.558	0.70
38_S	198_G	0.557	0.70
411_L	426_F	0.557	0.70
264_E	268_K	0.557	0.70
564_A	590_E	0.557	0.70
536_R	596_Q	0.556	0.70
43_T	46_G	0.556	0.70
559_A	564_A	0.556	0.70
532_L	581_K	0.555	0.70
571_A	586_A	0.554	0.69
266_A	281_V	0.554	0.69
222_N	323_A	0.554	0.69
89_M	93_I	0.554	0.69
22_T	385_D	0.554	0.69
156_D	160_I	0.553	0.69
598_L	604_Q	0.553	0.69
136_T	164_E	0.553	0.69
601_I	605_Q	0.551	0.69
195_L	316_S	0.551	0.69
281_V	298_I	0.551	0.69
590_E	595_S	0.550	0.69
544_H	548_K	0.550	0.69
445_R	450_D	0.550	0.69
545_S	553_A	0.550	0.69
286_I	295_H	0.548	0.69
59_V	260_Q	0.547	0.68
473_E	491_K	0.546	0.68
215_T	392_L	0.546	0.68
184_G	336_D	0.544	0.68
131_L	135_V	0.543	0.68
25_R	28_E	0.543	0.68
567_S	574_T	0.541	0.68
55_K	267_E	0.541	0.68
144_A	223_G	0.541	0.68
276_A	279_T	0.540	0.67
98_N	101_A	0.539	0.67
147_N	452_K	0.539	0.67
148_D	170_N	0.539	0.67
540_D	573_E	0.538	0.67
543_L	591_L	0.538	0.67
74_G	153_A	0.538	0.67
341_G	374_G	0.538	0.67
316_S	349_V	0.537	0.67
261_R	285_Y	0.537	0.67
386_V	389_V	0.537	0.67
17_A	379_G	0.537	0.67
554_G	558_P	0.537	0.67
487_S	496_E	0.536	0.67
29_N	32_G	0.535	0.67
475_T	487_S	0.535	0.67
14_S	199_T	0.535	0.67
438_I	472_I	0.534	0.67
116_S	120_L	0.534	0.67
518_D	522_N	0.534	0.67
129_D	363_K	0.534	0.67
538_Q	544_H	0.533	0.66
170_N	482_G	0.532	0.66
595_S	602_A	0.532	0.66
137_E	383_T	0.531	0.66
568_A	576_L	0.531	0.66
444_E	451_N	0.531	0.66
265_A	281_V	0.530	0.66
73_I	85_D	0.530	0.66
116_S	199_T	0.530	0.66
592_A	602_A	0.529	0.66
177_L	378_Q	0.529	0.66
70_K	371_V	0.527	0.66
514_K	517_R	0.526	0.65
325_Q	328_G	0.525	0.65
93_I	101_A	0.525	0.65
187_N	207_I	0.524	0.65
543_L	588_M	0.524	0.65
193_Y	200_F	0.523	0.65
70_K	172_P	0.523	0.65
586_A	596_Q	0.522	0.65
273_L	302_R	0.522	0.65
191_A	334_I	0.521	0.65
395_T	398_S	0.521	0.65
260_Q	338_I	0.520	0.65
142_V	151_R	0.520	0.65
414_K	444_E	0.519	0.64
546_T	557_L	0.519	0.64
3_K	140_I	0.519	0.64
133_E	137_E	0.518	0.64
89_M	103_V	0.518	0.64
11_T	172_P	0.517	0.64
155_K	481_D	0.517	0.64
549_Q	595_S	0.517	0.64
96_A	109_K	0.516	0.64
402_E	441_L	0.516	0.64
585_E	593_Q	0.516	0.64
413_A	416_T	0.516	0.64
244_F	294_K	0.516	0.64
259_M	263_K	0.515	0.64
218_V	393_D	0.515	0.64
121_K	124_K	0.514	0.64
195_L	349_V	0.514	0.64
151_R	482_G	0.514	0.64
252_L	258_A	0.513	0.64
198_G	223_G	0.513	0.64
595_S	600_E	0.511	0.63
559_A	567_S	0.511	0.63
432_N	466_P	0.511	0.63
555_D	563_T	0.510	0.63
121_K	523_A	0.509	0.63
412_I	420_T	0.509	0.63
470_P	490_D	0.509	0.63
551_E	570_T	0.508	0.63
94_I	100_D	0.508	0.63
529_F	533_V	0.507	0.63
227_L	231_D	0.507	0.63
345_R	369_E	0.507	0.63
75_R	78_Q	0.507	0.63
250_I	294_K	0.506	0.62
329_L	334_I	0.506	0.62
442_Q	452_K	0.506	0.62
76_R	100_D	0.505	0.62
173_T	180_G	0.504	0.62
576_L	581_K	0.504	0.62
511_E	515_M	0.504	0.62
569_L	595_S	0.503	0.62
408_M	451_N	0.503	0.62
476_F	484_L	0.502	0.62
399_L	486_V	0.502	0.62
569_L	572_L	0.501	0.62
561_D	599_M	0.501	0.62
125_K	334_I	0.500	0.62
316_S	352_K	0.500	0.62
587_K	594_V	0.500	0.62

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3d2fA	1	0.9436	100	0.153	Contact Map
4jneA	2	0.9404	100	0.175	Contact Map
4fl9A	1	0.8307	100	0.23	Contact Map
2v7yA	1	0.79	100	0.268	Contact Map
4rtfD	1	0.5455	100	0.282	Contact Map
3i33A	1	0.5815	100	0.475	Contact Map
4kboA	1	0.5862	100	0.478	Contact Map
4j8fA	2	0.8339	100	0.495	Contact Map
3qfuA	1	0.5846	100	0.532	Contact Map
4gniA	2	0.5768	100	0.532	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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