MNMG - ECOLI - GREMLIN Contacts

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MNMG - tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG

UniProt:	P0A6U3	Sequences: MFYPDPFDVIIIGGGHAGTEAAMAAARMGQQTLLLTHNIDTLGQMSCNPAIGGIGKGHLVKEVDALGGLMAKAIDQAGIQFRILNASKGPAVRATRAQADRVLYRQAVRTALENQPNLMIFQQAVEDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLDGKIHIGLDNYSGGRAGDPPSIPLSRRLRELPLRVGRLKTGTPPRIDARTIDFSVLAQQHGDNPMPVFSFMGNASQHPQQVPCYITHTNEKTHDVIRSNLDRSPMYAGVIEGVGPRYCPSIEDKVMRFADRNQHQIFLEPEGLTSNEIYPNGISTSLPFDVQMQIVRSMQGMENAKIVRPGYAIEYDFFDPRDLKPTLESKFIQGLFFAGQINGTTGYEEAAAQGLLAGLNAARLSADKEGWAPARSQAYLGVLVDDLCTLGTKEPYRMFTSRAEYRLMLREDNADLRLTEIGRELGLVDDERWARFNEKLENIERERQRLKSTWVTPSAEAAAEVNAHLTAPLSREASGEDLLRRPEMTYEKLTTLTPFAPALTDEQAAEQVEIQVKYEGYIARQQDEIEKQLRNENTLLPATLDYRQVSGLSNEVIAKLNDHKPASIGQASRISGVTPAAISILLVWLKKQGMLRRSA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10375
Length:	629 (615)
Sequences:	3094 (1714)
Seq/√Len:	69.1

ECOLI - MNMG
BACSU - MNMG TRMFO

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
253_D	257_S	4.865	1.00
577_R	591_N	4.749	1.00
217_Q	241_P	4.580	1.00
453_R	460_D	4.364	1.00
386_L	414_V	3.759	1.00
7_F	119_M	3.566	1.00
407_Q	451_I	3.399	1.00
192_L	359_S	3.301	1.00
259_L	285_M	3.244	1.00
246_H	292_Q	3.188	1.00
250_K	253_D	3.085	1.00
249_E	291_N	3.051	1.00
403_P	408_A	3.044	1.00
575_D	578_Q	2.903	1.00
460_D	464_A	2.900	1.00
112_L	120_I	2.863	1.00
251_T	327_S	2.860	1.00
210_I	307_I	2.741	1.00
74_I	99_A	2.693	1.00
248_N	329_Q	2.581	1.00
193_R	349_D	2.552	1.00
66_L	452_G	2.514	1.00
453_R	463_W	2.498	1.00
352_D	361_F	2.476	1.00
73_A	108_V	2.470	1.00
363_Q	394_L	2.467	1.00
393_R	398_K	2.427	1.00
261_R	319_D	2.398	1.00
356_T	400_G	2.391	1.00
127_D	186_R	2.384	1.00
230_M	462_R	2.382	1.00
452_G	458_V	2.347	1.00
208_R	305_N	2.325	1.00
148_A	151_V	2.317	1.00
476_E	479_R	2.317	1.00
393_R	401_W	2.299	1.00
193_R	352_D	2.295	1.00
450_E	454_E	2.264	1.00
325_V	334_A	2.262	1.00
471_E	475_R	2.257	1.00
450_E	470_L	2.250	1.00
212_F	307_I	2.242	1.00
211_D	214_V	2.241	1.00
59_L	382_A	2.239	1.00
297_L	331_M	2.239	1.00
76_Q	107_A	2.222	1.00
215_L	297_L	2.183	1.00
192_L	361_F	2.173	1.00
30_Q	396_A	2.159	1.00
32_T	118_L	2.156	1.00
42_L	120_I	2.109	1.00
23_M	69_L	2.103	1.00
326_R	334_A	2.099	1.00
481_K	510_E	2.073	1.00
19_T	43_G	2.067	1.00
446_L	470_L	2.061	1.00
31_Q	117_N	2.059	1.00
325_V	336_I	2.047	1.00
463_W	467_N	2.042	1.00
167_L	261_R	2.036	1.00
131_E	136_V	2.007	1.00
214_V	329_Q	2.002	1.00
206_D	209_T	1.991	1.00
6_P	147_R	1.985	1.00
356_T	366_F	1.969	1.00
386_L	410_L	1.968	1.00
160_D	188_R	1.966	1.00
556_Q	560_E	1.964	1.00
354_K	358_E	1.957	1.00
401_W	451_I	1.951	1.00
63_V	381_A	1.945	1.00
195_G	347_F	1.934	1.00
134_R	363_Q	1.933	1.00
59_L	428_M	1.928	1.00
219_H	241_P	1.920	1.00
257_S	323_Q	1.916	1.00
168_D	318_F	1.891	1.00
254_V	327_S	1.879	1.00
184_S	194_V	1.878	1.00
366_F	394_L	1.867	1.00
519_T	522_K	1.864	1.00
33_L	121_F	1.863	1.00
355_P	596_A	1.845	1.00
207_A	212_F	1.835	1.00
152_V	395_S	1.832	1.00
549_E	553_A	1.828	1.00
449_T	458_V	1.817	1.00
386_L	408_A	1.816	1.00
127_D	139_V	1.804	1.00
109_R	113_E	1.799	1.00
570_L	574_L	1.794	1.00
265_Y	285_M	1.790	1.00
10_I	148_A	1.789	1.00
150_A	394_L	1.781	1.00
203_P	325_V	1.777	1.00
214_V	332_E	1.777	1.00
107_A	110_T	1.775	1.00
139_V	145_K	1.768	1.00
127_D	189_E	1.768	1.00
150_A	366_F	1.753	1.00
393_R	454_E	1.744	1.00
206_D	335_K	1.743	1.00
39_I	120_I	1.726	1.00
392_A	396_A	1.716	1.00
586_V	607_V	1.711	1.00
28_M	393_R	1.702	1.00
150_A	395_S	1.698	1.00
6_P	149_K	1.697	1.00
30_Q	392_A	1.693	1.00
535_D	538_A	1.685	1.00
259_L	265_Y	1.681	1.00
206_D	305_N	1.679	1.00
472_N	538_A	1.673	0.99
449_T	462_R	1.662	0.99
12_I	125_V	1.656	0.99
510_E	546_V	1.653	0.99
569_L	596_A	1.635	0.99
297_L	307_I	1.634	0.99
386_L	403_P	1.614	0.99
163_I	172_G	1.613	0.99
250_K	323_Q	1.613	0.99
76_Q	111_A	1.598	0.99
306_E	337_V	1.594	0.99
401_W	455_L	1.587	0.99
500_T	517_E	1.572	0.99
63_V	385_L	1.564	0.99
226_V	231_G	1.554	0.99
210_I	215_L	1.554	0.99
322_M	336_I	1.553	0.99
9_V	25_A	1.539	0.99
451_I	454_E	1.533	0.99
540_E	544_I	1.521	0.99
74_I	97_A	1.514	0.99
130_V	190_L	1.511	0.99
188_R	194_V	1.510	0.99
445_D	469_K	1.506	0.99
45_M	99_A	1.506	0.99
115_Q	118_L	1.501	0.99
69_L	73_A	1.484	0.99
123_Q	140_T	1.484	0.99
211_D	333_N	1.475	0.99
484_W	508_S	1.462	0.99
570_L	591_N	1.458	0.99
364_G	394_L	1.456	0.99
358_E	394_L	1.454	0.99
476_E	542_V	1.454	0.99
205_I	334_A	1.452	0.99
476_E	520_Y	1.447	0.99
598_I	616_L	1.445	0.98
205_I	210_I	1.442	0.98
577_R	587_I	1.441	0.98
393_R	396_A	1.426	0.98
589_K	604_I	1.424	0.98
469_K	537_Q	1.417	0.98
553_A	556_Q	1.416	0.98
38_N	41_T	1.411	0.98
438_M	559_I	1.409	0.98
72_K	230_M	1.404	0.98
314_T	340_G	1.401	0.98
51_I	70_M	1.399	0.98
27_R	69_L	1.391	0.98
240_V	302_L	1.391	0.98
103_L	106_Q	1.390	0.98
215_L	245_T	1.387	0.98
230_M	458_V	1.379	0.98
207_A	304_S	1.378	0.98
77_A	107_A	1.371	0.98
474_E	478_Q	1.363	0.98
230_M	449_T	1.363	0.98
226_V	234_S	1.363	0.98
467_N	470_L	1.362	0.98
35_L	125_V	1.358	0.98
524_T	539_A	1.357	0.98
586_V	611_A	1.356	0.98
79_I	302_L	1.350	0.98
472_N	535_D	1.346	0.98
73_A	111_A	1.341	0.98
203_P	324_I	1.340	0.98
171_S	179_P	1.337	0.97
12_I	153_L	1.334	0.97
73_A	107_A	1.332	0.97
186_R	189_E	1.330	0.97
599_G	603_R	1.328	0.97
23_M	115_Q	1.327	0.97
69_L	111_A	1.321	0.97
470_L	474_E	1.318	0.97
258_N	261_R	1.315	0.97
102_V	303_T	1.309	0.97
591_N	594_K	1.306	0.97
79_I	240_V	1.306	0.97
30_Q	395_S	1.306	0.97
60_V	70_M	1.306	0.97
385_L	389_L	1.303	0.97
78_G	81_F	1.296	0.97
7_F	33_L	1.295	0.97
541_Q	544_I	1.295	0.97
468_E	472_N	1.292	0.97
483_T	509_G	1.288	0.97
412_V	433_A	1.285	0.97
463_W	466_F	1.283	0.97
256_R	288_A	1.283	0.97
129_I	137_G	1.279	0.97
185_R	189_E	1.278	0.97
584_N	588_A	1.274	0.97
355_P	418_C	1.272	0.97
80_Q	220_G	1.272	0.97
498_H	522_K	1.267	0.97
69_L	108_V	1.266	0.96
67_G	459_D	1.263	0.96
171_S	181_I	1.260	0.96
473_I	542_V	1.257	0.96
35_L	146_F	1.253	0.96
521_E	539_A	1.251	0.96
129_I	145_K	1.250	0.96
25_A	32_T	1.247	0.96
217_Q	243_Y	1.247	0.96
404_A	563_L	1.245	0.96
449_T	466_F	1.245	0.96
8_D	30_Q	1.241	0.96
37_H	124_A	1.238	0.96
350_P	421_G	1.234	0.96
249_E	253_D	1.230	0.96
460_D	463_W	1.227	0.96
560_E	563_L	1.226	0.96
130_V	362_I	1.226	0.96
155_V	371_I	1.224	0.96
180_S	184_S	1.223	0.96
348_F	367_F	1.219	0.96
203_P	334_A	1.219	0.96
253_D	256_R	1.215	0.96
23_M	27_R	1.212	0.96
162_K	169_N	1.206	0.95
245_T	331_M	1.204	0.95
207_A	307_I	1.203	0.95
263_P	266_A	1.199	0.95
382_A	413_L	1.192	0.95
404_A	407_Q	1.182	0.95
459_D	462_R	1.181	0.95
297_L	309_P	1.180	0.95
83_I	441_E	1.175	0.95
77_A	103_L	1.174	0.95
354_K	596_A	1.168	0.94
356_T	393_R	1.168	0.94
478_Q	481_K	1.166	0.94
464_A	468_E	1.160	0.94
446_L	541_Q	1.149	0.94
97_A	220_G	1.146	0.94
519_T	543_E	1.143	0.94
160_D	181_I	1.143	0.94
479_R	520_Y	1.137	0.94
584_N	587_I	1.135	0.94
249_E	256_R	1.128	0.93
588_A	592_D	1.116	0.93
160_D	184_S	1.116	0.93
574_L	618_W	1.114	0.93
572_A	596_A	1.114	0.93
28_M	455_L	1.113	0.93
446_L	545_Q	1.113	0.93
574_L	579_V	1.110	0.93
95_T	441_E	1.108	0.93
39_I	122_Q	1.108	0.93
186_R	190_L	1.104	0.93
478_Q	482_S	1.103	0.93
312_I	328_M	1.100	0.93
19_T	108_V	1.099	0.92
8_D	149_K	1.099	0.92
477_R	545_Q	1.098	0.92
130_V	133_D	1.098	0.92
481_K	549_E	1.096	0.92
123_Q	142_M	1.093	0.92
152_V	366_F	1.093	0.92
392_A	395_S	1.090	0.92
101_R	300_E	1.087	0.92
248_N	252_H	1.086	0.92
19_T	112_L	1.083	0.92
28_M	396_A	1.081	0.92
39_I	109_R	1.078	0.92
182_P	185_R	1.078	0.92
35_L	121_F	1.077	0.92
232_N	465_R	1.075	0.92
446_L	473_I	1.072	0.92
258_N	320_V	1.071	0.91
131_E	147_R	1.071	0.91
51_I	60_V	1.071	0.91
210_I	297_L	1.068	0.91
573_T	594_K	1.068	0.91
135_V	364_G	1.059	0.91
562_Q	599_G	1.058	0.91
93_R	540_E	1.057	0.91
570_L	576_Y	1.055	0.91
244_I	294_Q	1.053	0.91
250_K	327_S	1.053	0.91
322_M	326_R	1.051	0.91
406_S	563_L	1.051	0.91
496_N	502_P	1.047	0.91
495_V	500_T	1.047	0.91
255_I	280_I	1.047	0.91
252_H	256_R	1.046	0.91
10_I	33_L	1.045	0.90
464_A	467_N	1.045	0.90
566_E	603_R	1.044	0.90
553_A	557_D	1.042	0.90
69_L	72_K	1.040	0.90
185_R	188_R	1.036	0.90
468_E	471_E	1.036	0.90
494_E	498_H	1.035	0.90
153_L	187_L	1.033	0.90
598_I	612_I	1.033	0.90
161_G	179_P	1.029	0.90
102_V	106_Q	1.025	0.90
130_V	186_R	1.021	0.89
587_I	591_N	1.021	0.89
158_F	174_R	1.014	0.89
25_A	30_Q	1.010	0.89
312_I	325_V	1.009	0.89
138_A	151_V	1.009	0.89
34_L	112_L	1.007	0.89
9_V	150_A	1.001	0.88
126_E	141_Q	1.000	0.88
566_E	599_G	0.996	0.88
40_D	122_Q	0.992	0.88
129_I	136_V	0.992	0.88
9_V	395_S	0.991	0.88
230_M	461_E	0.981	0.87
207_A	305_N	0.978	0.87
433_A	439_L	0.972	0.87
600_Q	603_R	0.971	0.87
128_L	148_A	0.970	0.87
389_L	457_L	0.970	0.87
301_G	304_S	0.967	0.87
477_R	481_K	0.965	0.87
67_G	72_K	0.964	0.87
35_L	123_Q	0.963	0.86
113_E	120_I	0.960	0.86
398_K	454_E	0.957	0.86
312_I	324_I	0.956	0.86
126_E	182_P	0.955	0.86
315_S	342_A	0.951	0.86
322_M	325_V	0.951	0.86
205_I	331_M	0.950	0.86
174_R	177_D	0.947	0.86
422_T	589_K	0.947	0.86
322_M	335_K	0.945	0.85
231_G	234_S	0.943	0.85
570_L	619_L	0.941	0.85
192_L	348_F	0.941	0.85
583_S	586_V	0.937	0.85
197_L	347_F	0.937	0.85
410_L	414_V	0.935	0.85
129_I	139_V	0.934	0.85
54_I	94_A	0.932	0.85
39_I	113_E	0.932	0.85
5_D	31_Q	0.926	0.84
295_I	312_I	0.918	0.84
555_Q	558_E	0.918	0.84
366_F	395_S	0.917	0.84
452_G	457_L	0.915	0.84
140_T	146_F	0.913	0.83
57_G	227_F	0.912	0.83
167_L	260_D	0.912	0.83
19_T	73_A	0.911	0.83
51_I	74_I	0.907	0.83
210_I	331_M	0.904	0.83
288_A	292_Q	0.901	0.83
452_G	460_D	0.899	0.82
81_F	429_F	0.898	0.82
181_I	184_S	0.897	0.82
581_G	587_I	0.897	0.82
31_Q	119_M	0.896	0.82
160_D	194_V	0.895	0.82
63_V	70_M	0.892	0.82
28_M	457_L	0.892	0.82
164_H	268_V	0.891	0.82
494_E	497_A	0.888	0.82
518_M	522_K	0.886	0.82
129_I	147_R	0.884	0.81
445_D	449_T	0.883	0.81
14_G	34_L	0.883	0.81
192_L	367_F	0.881	0.81
193_R	361_F	0.880	0.81
149_K	395_S	0.879	0.81
54_I	429_F	0.878	0.81
35_L	138_A	0.878	0.81
393_R	455_L	0.877	0.81
602_S	612_I	0.875	0.81
484_W	506_E	0.875	0.81
608_T	611_A	0.874	0.81
422_T	605_S	0.873	0.81
194_V	348_F	0.873	0.81
245_T	295_I	0.873	0.81
261_R	320_V	0.872	0.80
318_F	322_M	0.871	0.80
476_E	533_L	0.871	0.80
23_M	112_L	0.869	0.80
119_M	335_K	0.869	0.80
215_L	331_M	0.860	0.80
169_N	268_V	0.860	0.80
326_R	335_K	0.860	0.80
453_R	459_D	0.856	0.79
136_V	147_R	0.853	0.79
135_V	363_Q	0.851	0.79
450_E	453_R	0.851	0.79
450_E	467_N	0.850	0.79
121_F	146_F	0.845	0.78
453_R	467_N	0.843	0.78
10_I	146_F	0.843	0.78
324_I	327_S	0.843	0.78
593_H	604_I	0.841	0.78
136_V	363_Q	0.840	0.78
406_S	562_Q	0.840	0.78
206_D	337_V	0.837	0.78
386_L	401_W	0.836	0.78
124_A	182_P	0.836	0.78
124_A	141_Q	0.834	0.77
480_L	509_G	0.831	0.77
572_A	594_K	0.831	0.77
215_L	328_M	0.830	0.77
522_K	525_T	0.828	0.77
322_M	339_P	0.826	0.77
354_K	572_A	0.825	0.77
110_T	114_N	0.822	0.76
613_S	617_V	0.822	0.76
389_L	393_R	0.822	0.76
77_A	99_A	0.819	0.76
350_P	422_T	0.816	0.76
336_I	339_P	0.815	0.76
520_Y	539_A	0.814	0.76
326_R	333_N	0.813	0.76
493_A	496_N	0.811	0.75
266_A	285_M	0.810	0.75
152_V	389_L	0.810	0.75
55_G	58_H	0.809	0.75
220_G	239_Q	0.809	0.75
192_L	362_I	0.808	0.75
205_I	309_P	0.808	0.75
83_I	95_T	0.807	0.75
128_L	151_V	0.806	0.75
32_T	115_Q	0.806	0.75
260_D	263_P	0.803	0.75
103_L	107_A	0.803	0.75
472_N	475_R	0.802	0.75
137_G	151_V	0.795	0.74
230_M	465_R	0.793	0.74
46_S	429_F	0.792	0.74
203_P	340_G	0.791	0.74
59_L	413_L	0.790	0.74
130_V	136_V	0.788	0.73
122_Q	306_E	0.788	0.73
250_K	254_V	0.788	0.73
389_L	401_W	0.786	0.73
149_K	364_G	0.785	0.73
215_L	329_Q	0.785	0.73
58_H	94_A	0.784	0.73
348_F	352_D	0.784	0.73
295_I	309_P	0.783	0.73
474_E	477_R	0.783	0.73
167_L	266_A	0.783	0.73
513_L	546_V	0.782	0.73
318_F	339_P	0.776	0.72
573_T	622_Q	0.776	0.72
44_Q	175_A	0.775	0.72
593_H	600_Q	0.774	0.72
61_K	95_T	0.774	0.72
354_K	363_Q	0.773	0.72
367_F	371_I	0.772	0.72
396_A	454_E	0.766	0.71
39_I	337_V	0.766	0.71
114_N	305_N	0.766	0.71
209_T	335_K	0.764	0.71
466_F	470_L	0.764	0.71
243_Y	307_I	0.764	0.71
74_I	227_F	0.764	0.71
404_A	562_Q	0.764	0.71
128_L	137_G	0.764	0.71
148_A	364_G	0.764	0.71
446_L	466_F	0.764	0.71
382_A	428_M	0.763	0.71
288_A	291_N	0.763	0.71
250_K	257_S	0.759	0.70
41_T	177_D	0.757	0.70
95_T	310_N	0.754	0.70
128_L	135_V	0.754	0.70
106_Q	303_T	0.754	0.70
265_Y	282_D	0.753	0.70
475_R	478_Q	0.752	0.70
164_H	343_I	0.751	0.70
160_D	185_R	0.747	0.69
527_T	530_A	0.747	0.69
33_L	146_F	0.746	0.69
101_R	309_P	0.745	0.69
477_R	542_V	0.745	0.69
174_R	343_I	0.745	0.69
560_E	564_R	0.744	0.69
55_G	428_M	0.744	0.69
72_K	111_A	0.744	0.69
24_A	457_L	0.744	0.69
109_R	337_V	0.744	0.69
238_Q	302_L	0.743	0.69
255_I	284_V	0.743	0.69
23_M	111_A	0.742	0.69
39_I	112_L	0.741	0.69
137_G	148_A	0.741	0.69
399_E	454_E	0.740	0.69
571_P	594_K	0.740	0.69
11_I	25_A	0.740	0.69
67_G	462_R	0.738	0.68
61_K	441_E	0.737	0.68
404_A	599_G	0.736	0.68
162_K	171_S	0.735	0.68
107_A	111_A	0.734	0.68
580_S	587_I	0.734	0.68
139_V	186_R	0.733	0.68
164_H	169_N	0.731	0.68
223_P	536_E	0.729	0.67
486_T	506_E	0.728	0.67
212_F	243_Y	0.727	0.67
413_L	428_M	0.727	0.67
469_K	541_Q	0.727	0.67
497_A	525_T	0.725	0.67
252_H	284_V	0.725	0.67
604_I	607_V	0.723	0.67
366_F	393_R	0.722	0.67
136_V	149_K	0.719	0.66
153_L	367_F	0.718	0.66
261_R	317_P	0.718	0.66
356_T	401_W	0.717	0.66
46_S	54_I	0.716	0.66
69_L	112_L	0.716	0.66
541_Q	545_Q	0.714	0.66
409_Y	433_A	0.714	0.66
559_I	562_Q	0.713	0.66
165_I	339_P	0.712	0.66
50_A	310_N	0.711	0.65
521_E	536_E	0.710	0.65
79_I	301_G	0.708	0.65
543_E	547_K	0.707	0.65
10_I	125_V	0.707	0.65
37_H	41_T	0.707	0.65
208_R	335_K	0.706	0.65
586_V	608_T	0.706	0.65
40_D	109_R	0.705	0.65
266_A	282_D	0.705	0.65
514_R	549_E	0.704	0.65
477_R	546_V	0.704	0.65
28_M	392_A	0.702	0.64
435_Y	559_I	0.702	0.64
513_L	518_M	0.701	0.64
413_L	589_K	0.701	0.64
453_R	466_F	0.701	0.64
136_V	139_V	0.701	0.64
446_L	450_E	0.699	0.64
309_P	334_A	0.699	0.64
43_G	101_R	0.699	0.64
305_N	337_V	0.698	0.64
419_T	600_Q	0.698	0.64
359_S	362_I	0.697	0.64
450_E	466_F	0.697	0.64
57_G	83_I	0.696	0.64
167_L	268_V	0.695	0.64
248_N	327_S	0.695	0.64
167_L	263_P	0.692	0.63
12_I	155_V	0.691	0.63
41_T	44_Q	0.691	0.63
245_T	329_Q	0.690	0.63
135_V	151_V	0.689	0.63
216_A	292_Q	0.689	0.63
420_L	605_S	0.689	0.63
140_T	263_P	0.689	0.63
408_A	412_V	0.689	0.63
518_M	523_L	0.688	0.63
319_D	323_Q	0.688	0.63
282_D	315_S	0.687	0.63
562_Q	612_I	0.687	0.63
174_R	429_F	0.687	0.63
429_F	608_T	0.687	0.63
449_T	452_G	0.686	0.63
133_D	363_Q	0.686	0.63
479_R	483_T	0.685	0.63
309_P	611_A	0.685	0.63
9_V	30_Q	0.684	0.62
61_K	83_I	0.684	0.62
264_M	319_D	0.682	0.62
317_P	320_V	0.682	0.62
14_G	108_V	0.682	0.62
77_A	97_A	0.681	0.62
476_E	530_A	0.681	0.62
557_D	560_E	0.681	0.62
509_G	527_T	0.679	0.62
323_Q	327_S	0.678	0.62
325_V	340_G	0.678	0.62
580_S	614_I	0.677	0.62
158_F	161_G	0.676	0.62
357_L	414_V	0.676	0.62
489_A	493_A	0.676	0.62
360_K	593_H	0.675	0.61
58_H	428_M	0.673	0.61
489_A	506_E	0.673	0.61
355_P	419_T	0.671	0.61
349_D	352_D	0.671	0.61
191_P	352_D	0.670	0.61
67_G	457_L	0.669	0.61
86_A	93_R	0.667	0.61
14_G	43_G	0.667	0.61
193_R	592_D	0.665	0.60
10_I	138_A	0.665	0.60
73_A	99_A	0.664	0.60
382_A	410_L	0.662	0.60
242_C	299_P	0.661	0.60
372_N	383_Q	0.661	0.60
252_H	292_Q	0.659	0.60
349_D	421_G	0.659	0.60
458_V	466_F	0.657	0.59
498_H	518_M	0.657	0.59
232_N	235_Q	0.657	0.59
327_S	334_A	0.656	0.59
306_E	338_R	0.656	0.59
152_V	392_A	0.655	0.59
512_L	518_M	0.655	0.59
141_Q	178_P	0.654	0.59
511_D	514_R	0.654	0.59
207_A	243_Y	0.654	0.59
126_E	139_V	0.652	0.59
247_T	280_I	0.652	0.59
103_L	302_L	0.652	0.59
613_S	616_L	0.652	0.59
583_S	608_T	0.650	0.59
280_I	314_T	0.650	0.59
158_F	177_D	0.650	0.59
250_K	329_Q	0.649	0.58
37_H	180_S	0.649	0.58
163_I	343_I	0.648	0.58
251_T	254_V	0.648	0.58
46_S	310_N	0.646	0.58
359_S	371_I	0.646	0.58
399_E	569_L	0.646	0.58
110_T	303_T	0.646	0.58
63_V	382_A	0.645	0.58
9_V	152_V	0.644	0.58
46_S	174_R	0.643	0.58
252_H	288_A	0.643	0.58
309_P	312_I	0.639	0.57
27_R	115_Q	0.638	0.57
323_Q	326_R	0.637	0.57
388_G	391_A	0.636	0.57
23_M	73_A	0.636	0.57
258_N	265_Y	0.636	0.57
367_F	429_F	0.635	0.57
266_A	271_G	0.634	0.57
258_N	316_L	0.634	0.57
464_A	475_R	0.632	0.56
54_I	81_F	0.632	0.56
255_I	324_I	0.632	0.56
573_T	619_L	0.631	0.56
46_S	81_F	0.631	0.56
76_Q	110_T	0.630	0.56
186_R	194_V	0.630	0.56
80_Q	239_Q	0.630	0.56
109_R	206_D	0.627	0.56
263_P	268_V	0.627	0.56
487_P	506_E	0.627	0.56
198_K	313_S	0.627	0.56
513_L	523_L	0.626	0.56
43_G	108_V	0.626	0.56
93_R	441_E	0.626	0.56
44_Q	122_Q	0.625	0.56
214_V	330_G	0.624	0.55
450_E	463_W	0.624	0.55
259_L	266_A	0.623	0.55
25_A	33_L	0.623	0.55
159_L	180_S	0.622	0.55
186_R	362_I	0.622	0.55
579_V	582_L	0.620	0.55
476_E	480_L	0.620	0.55
474_E	481_K	0.619	0.55
264_M	315_S	0.619	0.55
351_R	421_G	0.619	0.55
82_R	218_Q	0.618	0.55
213_S	333_N	0.618	0.55
570_L	577_R	0.618	0.55
81_F	95_T	0.617	0.55
81_F	97_A	0.616	0.55
109_R	122_Q	0.616	0.55
422_T	438_M	0.616	0.55
274_P	313_S	0.615	0.54
261_R	264_M	0.615	0.54
453_R	458_V	0.615	0.54
359_S	367_F	0.614	0.54
408_A	422_T	0.613	0.54
530_A	533_L	0.613	0.54
164_H	310_N	0.612	0.54
122_Q	338_R	0.609	0.54
324_I	328_M	0.608	0.54
44_Q	101_R	0.608	0.54
323_Q	329_Q	0.606	0.53
22_A	34_L	0.606	0.53
395_S	398_K	0.605	0.53
174_R	310_N	0.605	0.53
50_A	54_I	0.605	0.53
164_H	429_F	0.605	0.53
154_T	347_F	0.605	0.53
174_R	347_F	0.604	0.53
167_L	319_D	0.603	0.53
359_S	363_Q	0.603	0.53
328_M	332_E	0.601	0.53
46_S	158_F	0.600	0.53
442_D	541_Q	0.599	0.52
46_S	95_T	0.598	0.52
158_F	429_F	0.597	0.52
198_K	269_I	0.597	0.52
471_E	474_E	0.597	0.52
25_A	150_A	0.597	0.52
401_W	454_E	0.597	0.52
504_S	507_A	0.596	0.52
492_A	495_V	0.596	0.52
162_K	180_S	0.596	0.52
246_H	291_N	0.596	0.52
12_I	151_V	0.595	0.52
508_S	582_L	0.595	0.52
54_I	57_G	0.593	0.52
267_G	282_D	0.593	0.52
94_A	429_F	0.593	0.52
218_Q	242_C	0.593	0.52
487_P	503_L	0.593	0.52
55_G	375_T	0.592	0.52
184_S	188_R	0.589	0.51
226_V	428_M	0.589	0.51
536_E	540_E	0.588	0.51
76_Q	235_Q	0.588	0.51
219_H	222_N	0.587	0.51
348_F	598_I	0.585	0.51
69_L	115_Q	0.585	0.51
54_I	95_T	0.585	0.51
128_L	153_L	0.584	0.51
489_A	492_A	0.584	0.51
261_R	323_Q	0.583	0.51
258_N	324_I	0.581	0.50
19_T	22_A	0.579	0.50
382_A	385_L	0.579	0.50
315_S	319_D	0.577	0.50
257_S	260_D	0.577	0.50
256_R	284_V	0.576	0.50
182_P	187_L	0.575	0.50
533_L	542_V	0.575	0.50
216_A	244_I	0.573	0.49
129_I	151_V	0.572	0.49
14_G	120_I	0.572	0.49
206_D	304_S	0.570	0.49
429_F	441_E	0.570	0.49
126_E	143_G	0.570	0.49
131_E	145_K	0.570	0.49
310_N	429_F	0.569	0.49
284_V	314_T	0.569	0.49
467_N	471_E	0.569	0.49
57_G	87_S	0.569	0.49
576_Y	591_N	0.568	0.49
55_G	94_A	0.567	0.49
510_E	514_R	0.566	0.49
271_G	382_A	0.566	0.49
116_P	208_R	0.566	0.49
422_T	604_I	0.566	0.49
25_A	29_G	0.565	0.48
403_P	455_L	0.565	0.48
268_V	271_G	0.565	0.48
310_N	328_M	0.564	0.48
267_G	342_A	0.564	0.48
28_M	386_L	0.564	0.48
128_L	186_R	0.563	0.48
264_M	342_A	0.563	0.48
162_K	270_E	0.563	0.48
503_L	507_A	0.562	0.48
5_D	119_M	0.562	0.48
258_N	323_Q	0.562	0.48
476_E	539_A	0.562	0.48
388_G	392_A	0.562	0.48
129_I	148_A	0.561	0.48
78_G	429_F	0.561	0.48
121_F	335_K	0.560	0.48
237_P	302_L	0.559	0.48
162_K	172_G	0.558	0.48
538_A	541_Q	0.558	0.48
200_G	313_S	0.558	0.48
435_Y	566_E	0.557	0.47
296_F	314_T	0.557	0.47
78_G	310_N	0.557	0.47
24_A	27_R	0.556	0.47
165_I	168_D	0.556	0.47
202_P	313_S	0.556	0.47
318_F	336_I	0.555	0.47
50_A	79_I	0.555	0.47
14_G	42_L	0.554	0.47
149_K	454_E	0.554	0.47
70_M	104_Y	0.552	0.47
140_T	144_L	0.552	0.47
435_Y	554_R	0.551	0.47
50_A	297_L	0.550	0.47
545_Q	549_E	0.549	0.46
567_N	579_V	0.549	0.46
254_V	323_Q	0.549	0.46
258_N	266_A	0.548	0.46
10_I	128_L	0.548	0.46
245_T	309_P	0.548	0.46
315_S	551_Y	0.547	0.46
103_L	303_T	0.547	0.46
78_G	224_M	0.546	0.46
272_V	347_F	0.545	0.46
580_S	618_W	0.545	0.46
135_V	148_A	0.543	0.46
65_A	445_D	0.543	0.46
435_Y	555_Q	0.543	0.46
257_S	320_V	0.542	0.46
180_S	186_R	0.541	0.46
568_T	619_L	0.541	0.46
108_V	112_L	0.541	0.46
246_H	288_A	0.540	0.45
461_E	464_A	0.540	0.45
155_V	348_F	0.539	0.45
510_E	549_E	0.539	0.45
282_D	296_F	0.539	0.45
111_A	114_N	0.538	0.45
264_M	282_D	0.537	0.45
59_L	154_T	0.536	0.45
403_P	407_Q	0.536	0.45
245_T	328_M	0.536	0.45
83_I	86_A	0.536	0.45
347_F	429_F	0.535	0.45
230_M	459_D	0.535	0.45
414_V	498_H	0.534	0.45
356_T	396_A	0.534	0.45
55_G	337_V	0.533	0.45
413_L	605_S	0.533	0.45
163_I	170_Y	0.533	0.45
148_A	523_L	0.532	0.44
286_R	584_N	0.532	0.44
44_Q	105_R	0.532	0.44
458_V	462_R	0.532	0.44
208_R	304_S	0.531	0.44
472_N	542_V	0.530	0.44
461_E	465_R	0.530	0.44
348_F	359_S	0.530	0.44
169_N	262_S	0.529	0.44
274_P	375_T	0.529	0.44
258_N	319_D	0.528	0.44
81_F	164_H	0.527	0.44
54_I	93_R	0.527	0.44
205_I	307_I	0.526	0.44
360_K	600_Q	0.526	0.44
273_G	313_S	0.525	0.44
294_Q	439_L	0.525	0.44
485_V	493_A	0.524	0.43
494_E	500_T	0.524	0.43
262_S	315_S	0.524	0.43
161_G	165_I	0.524	0.43
46_S	197_L	0.524	0.43
320_V	323_Q	0.524	0.43
97_A	227_F	0.524	0.43
272_V	579_V	0.523	0.43
125_V	138_A	0.523	0.43
70_M	74_I	0.522	0.43
282_D	342_A	0.522	0.43
224_M	233_A	0.522	0.43
441_E	608_T	0.521	0.43
136_V	148_A	0.521	0.43
264_M	269_I	0.521	0.43
54_I	375_T	0.520	0.43
74_I	77_A	0.520	0.43
285_M	431_S	0.519	0.43
569_L	597_S	0.519	0.43
280_I	296_F	0.519	0.43
537_Q	569_L	0.518	0.43
505_R	511_D	0.518	0.43
442_D	544_I	0.518	0.43
554_R	564_R	0.517	0.43
266_A	340_G	0.516	0.43
510_E	545_Q	0.516	0.43
23_M	67_G	0.516	0.43
180_S	188_R	0.516	0.43
46_S	347_F	0.516	0.43
355_P	402_A	0.516	0.43
281_E	315_S	0.515	0.42
259_L	324_I	0.515	0.42
399_E	471_E	0.514	0.42
190_L	362_I	0.513	0.42
446_L	469_K	0.513	0.42
134_R	150_A	0.513	0.42
473_I	545_Q	0.513	0.42
357_L	386_L	0.512	0.42
142_M	318_F	0.511	0.42
58_H	409_Y	0.511	0.42
250_K	471_E	0.511	0.42
8_D	31_Q	0.511	0.42
104_Y	108_V	0.511	0.42
108_V	111_A	0.510	0.42
607_V	610_A	0.509	0.42
43_G	73_A	0.509	0.42
539_A	542_V	0.509	0.42
520_Y	543_E	0.509	0.42
90_P	442_D	0.509	0.42
342_A	372_N	0.508	0.42
479_R	533_L	0.507	0.41
78_G	99_A	0.507	0.41
437_L	555_Q	0.507	0.41
280_I	316_L	0.507	0.41
451_I	455_L	0.506	0.41
250_K	332_E	0.506	0.41
162_K	271_G	0.506	0.41
134_R	364_G	0.505	0.41
309_P	325_V	0.505	0.41
262_S	268_V	0.505	0.41
44_Q	177_D	0.505	0.41
272_V	588_A	0.504	0.41
30_Q	375_T	0.504	0.41
72_K	76_Q	0.504	0.41
159_L	184_S	0.503	0.41
487_P	505_R	0.503	0.41
172_G	554_R	0.502	0.41
255_I	316_L	0.502	0.41
493_A	497_A	0.501	0.41
101_R	215_L	0.501	0.41
468_E	475_R	0.500	0.41
55_G	154_T	0.500	0.41
523_L	543_E	0.500	0.41
73_A	76_Q	0.500	0.41

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3cesA	2	0.8299	100	0.362	Contact Map
3cp8A	2	0.9587	100	0.372	Contact Map
2zxiA	2	0.9475	100	0.402	Contact Map
3g5sA	1	0.6153	100	0.725	Contact Map
2culA	1	0.3529	100	0.879	Contact Map
3v76A	2	0.531	100	0.892	Contact Map
3nlcA	1	0.5851	100	0.893	Contact Map
4cnkA	2	0.5421	100	0.909	Contact Map
2i0zA	1	0.5453	99.8	0.932	Contact Map
1y0pA	1	0.5644	99.7	0.938	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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