GREMLIN Database
G6PI - Glucose-6-phosphate isomerase
UniProt: P0A6T1 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10702
Length: 549 (527)
Sequences: 2509 (1373)
Seq/√Len: 59.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
497_G504_T4.2251.00
74_D77_G4.0491.00
18_H62_T3.3121.00
405_A421_L3.1041.00
336_L389_Y3.0471.00
249_A252_E3.0191.00
441_E455_D2.9621.00
309_A315_V2.9181.00
273_L293_L2.8841.00
38_F539_G2.8371.00
71_K76_A2.8111.00
128_K291_V2.8041.00
325_N397_K2.8031.00
145_K199_E2.7991.00
408_I476_E2.7681.00
189_I221_S2.7191.00
18_H65_K2.7071.00
149_D179_H2.6121.00
404_I474_L2.6111.00
324_Y328_F2.5851.00
71_K310_E2.5601.00
56_N470_N2.5341.00
224_D228_K2.5281.00
87_K93_N2.5211.00
11_A72_E2.5031.00
360_Y464_E2.5021.00
62_T65_K2.4321.00
289_N292_E2.4161.00
352_G493_I2.3961.00
299_A480_F2.3811.00
19_F328_F2.3641.00
40_K60_E2.3551.00
437_R458_V2.2921.00
34_D40_K2.2901.00
292_E480_F2.2631.00
76_A309_A2.2621.00
99_V109_I2.2561.00
368_V372_T2.2311.00
425_F544_Y2.2241.00
206_A277_I2.2231.00
78_A363_R2.2201.00
429_E533_H2.2101.00
76_A79_I2.2051.00
302_K306_T2.1611.00
362_D366_N2.1451.00
330_A398_M2.0671.00
51_V470_N2.0601.00
83_F305_S2.0581.00
344_R379_E2.0211.00
149_D177_N2.0201.00
114_K119_E2.0061.00
80_K305_S1.9991.00
344_R347_A1.9941.00
88_I96_V1.9931.00
51_V317_L1.9751.00
250_V260_M1.9701.00
63_L316_L1.9531.00
167_E343_H1.9351.00
26_T29_D1.9301.00
336_L401_C1.9291.00
130_F261_F1.9281.00
204_L243_L1.9251.00
131_S283_L1.8761.00
428_T471_S1.8751.00
36_D39_S1.8531.00
317_L488_L1.8401.00
523_E533_H1.8391.00
106_N121_N1.8391.00
80_K84_S1.8261.00
104_R298_H1.8211.00
436_S439_V1.8030.99
56_N324_Y1.7990.99
435_K443_E1.7960.99
221_S416_H1.7940.99
331_E397_K1.7840.99
51_V313_L1.7830.99
78_A81_S1.7740.99
139_W147_I1.7710.99
371_Q397_K1.7630.99
405_A424_F1.7620.99
149_D200_T1.7590.99
104_R121_N1.7560.99
148_T200_T1.7530.99
103_N117_M1.7420.99
230_A235_H1.7390.99
96_V504_T1.7380.99
273_L281_I1.7100.99
81_S86_E1.7050.99
335_I349_F1.7050.99
246_N249_A1.6920.99
319_L499_I1.6870.99
133_A138_E1.6790.99
53_Y63_L1.6690.99
424_F471_S1.6580.99
43_A313_L1.6560.99
29_D33_K1.6560.99
43_A53_Y1.6500.99
38_F50_L1.6490.99
282_V287_F1.6420.99
165_V281_I1.6330.99
191_E341_Y1.6290.99
171_P410_H1.6250.99
313_L488_L1.6120.99
131_S287_F1.6090.99
115_D118_P1.6050.99
78_A498_V1.5820.99
206_A243_L1.5780.99
68_D71_K1.5740.99
128_K287_F1.5630.99
109_I118_P1.5620.99
51_V472_I1.5340.98
105_S125_E1.5340.98
247_A257_T1.5340.98
217_T419_K1.5310.98
22_M25_V1.5250.98
321_G353_N1.5180.98
131_S282_V1.5170.98
41_F60_E1.5030.98
46_D299_A1.5020.98
59_T62_T1.4930.98
251_G257_T1.4610.98
192_V196_V1.4580.98
226_F230_A1.4540.98
362_D501_N1.4510.98
384_G389_Y1.4460.98
131_S135_I1.4430.98
75_L79_I1.4390.97
142_Y230_A1.4340.97
247_A260_M1.4310.97
357_N504_T1.4250.97
302_K305_S1.4200.97
108_P115_D1.4130.97
406_P474_L1.4100.97
274_W297_A1.4080.97
46_D484_A1.4070.97
424_F428_T1.4050.97
14_A68_D1.3960.97
480_F484_A1.3950.97
151_V203_F1.3950.97
44_T543_R1.3950.97
415_D419_K1.3870.97
143_T199_E1.3860.97
21_E61_E1.3810.97
165_V293_L1.3810.97
392_I399_V1.3780.97
244_S250_V1.3770.97
367_V464_E1.3750.97
181_V189_I1.3720.97
408_I475_R1.3680.97
336_L384_G1.3670.97
107_T302_K1.3540.96
363_R501_N1.3390.96
26_T57_R1.3330.96
204_L241_A1.3280.96
213_Q521_L1.3280.96
159_D163_Y1.3280.96
55_K536_S1.3260.96
421_L425_F1.3250.96
428_T469_T1.3200.96
49_M474_L1.3180.96
43_A316_L1.3140.96
300_M488_L1.3100.96
425_F473_L1.3090.96
307_T311_K1.3060.96
198_P225_W1.3050.95
322_I499_I1.3050.95
437_R441_E1.2990.95
122_A126_K1.2980.95
79_I309_A1.2810.95
538_N542_N1.2760.95
28_A439_V1.2740.95
353_N373_G1.2720.95
75_L315_V1.2660.95
42_S50_L1.2630.95
71_K309_A1.2630.95
91_T460_F1.2570.94
67_Q316_L1.2550.94
379_E388_F1.2520.94
318_A322_I1.2470.94
141_G147_I1.2450.94
326_N500_L1.2390.94
90_R363_R1.2380.94
87_K112_D1.2310.94
50_L543_R1.2260.94
149_D197_N1.2260.94
135_I283_L1.2250.94
38_F42_S1.2230.94
82_M96_V1.2160.93
421_L544_Y1.2160.93
474_L477_I1.2140.93
418_Q544_Y1.2110.93
58_I320_I1.2090.93
105_S121_N1.2060.93
13_Q16_Q1.2060.93
96_V497_G1.2040.93
25_V30_L1.2000.93
520_I523_E1.1980.93
347_A379_E1.1930.93
404_I477_I1.1920.93
189_I193_L1.1770.92
28_A436_S1.1760.92
457_V461_K1.1700.92
332_T377_W1.1580.92
148_T179_H1.1560.92
27_I57_R1.1550.92
430_A516_L1.1550.92
19_F23_K1.1510.91
281_I293_L1.1510.91
103_N298_H1.1460.91
321_G492_K1.1460.91
165_V273_L1.1450.91
321_G496_Q1.1400.91
339_D406_P1.1390.91
82_M88_I1.1370.91
166_T180_F1.1360.91
51_V300_M1.1340.91
134_I283_L1.1320.91
18_H22_M1.1320.91
79_I304_F1.1300.91
20_D23_K1.1280.91
163_Y343_H1.1240.90
198_P229_A1.1240.90
405_A473_L1.1220.90
232_D235_H1.1220.90
108_P117_M1.1180.90
41_F58_I1.1170.90
130_F241_A1.1170.90
360_Y367_V1.1080.90
315_V495_T1.1080.90
109_I117_M1.1050.90
186_G416_H1.0990.89
247_A251_G1.0990.89
45_F484_A1.0990.89
104_R295_S1.0990.89
16_Q20_D1.0990.89
163_Y344_R1.0980.89
75_L318_A1.0960.89
90_R503_F1.0950.89
402_D470_N1.0930.89
69_L499_I1.0850.89
340_Q343_H1.0840.89
333_E353_N1.0830.89
64_A310_E1.0830.89
401_C469_T1.0730.88
148_T177_N1.0730.88
38_F535_S1.0730.88
403_F469_T1.0690.88
117_M121_N1.0620.88
22_M328_F1.0590.88
187_T411_N1.0580.87
429_E523_E1.0550.87
478_T481_S1.0530.87
323_W327_F1.0520.87
22_M57_R1.0500.87
375_I397_K1.0480.87
64_A68_D1.0460.87
103_N109_I1.0340.86
181_V222_A1.0340.86
36_D40_K1.0340.86
45_F300_M1.0330.86
44_T48_Q1.0270.86
179_H192_V1.0270.86
440_V458_V1.0260.86
192_V195_K1.0200.85
14_A65_K1.0140.85
65_K68_D1.0130.85
227_L236_V1.0080.85
127_M282_V1.0080.85
68_D72_E1.0060.85
345_F485_L1.0030.85
184_V217_T1.0020.84
542_N545_K1.0010.84
438_E441_E0.9960.84
129_T133_A0.9920.84
18_H59_T0.9890.84
373_G391_L0.9880.84
22_M62_T0.9840.83
257_T260_M0.9830.83
67_Q315_V0.9830.83
435_K515_Q0.9820.83
349_F352_G0.9810.83
119_E262_E0.9800.83
58_I63_L0.9740.83
300_M313_L0.9740.83
389_Y401_C0.9730.83
46_D480_F0.9720.83
60_E64_A0.9720.83
70_A319_L0.9710.83
248_K252_E0.9690.82
77_G81_S0.9680.82
61_E65_K0.9660.82
122_A262_E0.9610.82
123_V262_E0.9610.82
189_I222_A0.9600.82
45_F313_L0.9570.82
50_L539_G0.9570.82
167_E170_R0.9560.82
362_D368_V0.9550.81
538_N545_K0.9540.81
75_L309_A0.9540.81
45_F48_Q0.9530.81
320_I324_Y0.9500.81
300_M472_I0.9480.81
179_H195_K0.9470.81
341_Y411_N0.9470.81
45_F299_A0.9450.81
227_L230_A0.9440.81
31_F55_K0.9400.80
221_S413_L0.9380.80
57_R466_N0.9370.80
407_A543_R0.9370.80
364_N501_N0.9370.80
178_M284_S0.9360.80
103_N108_P0.9360.80
121_N298_H0.9330.80
243_L277_I0.9320.80
474_L481_S0.9320.80
140_K146_A0.9320.80
104_R117_M0.9310.80
187_T339_D0.9300.80
63_L67_Q0.9300.80
226_F240_F0.9300.80
123_V276_A0.9290.80
27_I432_A0.9290.80
520_I533_H0.9260.79
146_A200_T0.9260.79
409_T412_P0.9250.79
53_Y470_N0.9180.79
419_K521_L0.9170.79
9_T73_C0.9170.79
530_I542_N0.9160.79
105_S108_P0.9130.78
247_A250_V0.9090.78
407_A475_R0.9080.78
167_E344_R0.9080.78
454_L458_V0.9060.78
48_Q484_A0.9040.78
166_T284_S0.9020.78
437_R462_V0.9020.78
21_E59_T0.9010.78
10_A72_E0.9000.77
103_N121_N0.8990.77
14_A18_H0.8980.77
421_L473_L0.8980.77
48_Q475_R0.8970.77
124_L291_V0.8960.77
343_H379_E0.8920.77
326_N371_Q0.8900.77
191_E194_K0.8850.76
337_P379_E0.8840.76
61_E64_A0.8840.76
443_E515_Q0.8810.76
281_I285_I0.8800.76
295_S298_H0.8790.76
245_T250_V0.8770.76
298_H302_K0.8760.76
433_F439_V0.8760.76
150_V204_L0.8730.75
22_M26_T0.8720.75
125_E291_V0.8690.75
152_N159_D0.8670.75
188_H340_Q0.8660.75
67_Q319_L0.8650.75
287_F291_V0.8620.74
187_T191_E0.8610.74
406_P477_I0.8570.74
533_H538_N0.8570.74
103_N107_T0.8520.74
331_E371_Q0.8510.73
441_E458_V0.8490.73
429_E433_F0.8480.73
291_V295_S0.8450.73
82_M99_V0.8430.73
67_Q310_E0.8400.72
304_F495_T0.8330.72
203_F222_A0.8290.71
67_Q71_K0.8290.71
264_W276_A0.8290.71
145_K200_T0.8290.71
322_I326_N0.8280.71
179_H200_T0.8270.71
292_E295_S0.8270.71
165_V486_I0.8250.71
460_F508_W0.8240.71
44_T50_L0.8240.71
531_S538_N0.8230.71
335_I352_G0.8230.71
149_D196_V0.8200.71
187_T341_Y0.8190.71
245_T263_F0.8170.70
128_K132_E0.8140.70
477_I482_L0.8100.70
318_A495_T0.8090.70
256_D260_M0.8080.69
409_T417_H0.8050.69
353_N492_K0.8050.69
332_T375_I0.8020.69
313_L317_L0.8010.69
227_L231_G0.8000.69
126_K262_E0.7980.69
73_C501_N0.7980.69
153_I222_A0.7960.68
57_R324_Y0.7950.68
494_F498_V0.7940.68
317_L470_N0.7930.68
146_A175_H0.7920.68
333_E496_Q0.7910.68
111_V115_D0.7900.68
143_T230_A0.7880.68
453_T456_Y0.7850.67
344_R380_P0.7840.67
188_H383_N0.7840.67
226_F235_H0.7840.67
166_T281_I0.7840.67
209_T263_F0.7810.67
104_R291_V0.7800.67
418_Q525_K0.7800.67
541_I545_K0.7790.67
172_Y479_P0.7780.67
205_V219_A0.7770.66
139_W259_N0.7750.66
333_E402_D0.7740.66
135_I176_L0.7730.66
321_G333_E0.7720.66
538_N541_I0.7680.66
145_K197_N0.7680.66
362_D370_Y0.7680.66
12_W327_F0.7670.65
377_W387_A0.7650.65
141_G144_G0.7640.65
105_S298_H0.7620.65
285_I289_N0.7610.65
105_S117_M0.7590.65
376_I492_K0.7580.65
401_C428_T0.7540.64
27_I30_L0.7490.64
148_T197_N0.7490.64
320_I333_E0.7490.64
213_Q217_T0.7490.64
88_I494_F0.7440.63
226_F236_V0.7420.63
55_K471_S0.7420.63
299_A484_A0.7400.63
104_R107_T0.7380.62
31_F54_S0.7350.62
53_Y316_L0.7330.62
113_G116_V0.7330.62
191_E411_N0.7320.62
213_Q419_K0.7310.62
331_E375_I0.7300.62
303_H314_P0.7290.62
216_M220_H0.7280.61
295_S299_A0.7280.61
51_V488_L0.7270.61
43_A311_K0.7270.61
223_R227_L0.7260.61
151_V201_T0.7250.61
245_T260_M0.7230.61
473_L543_R0.7220.61
133_A139_W0.7200.61
167_E341_Y0.7200.61
459_P462_V0.7200.61
9_T72_E0.7200.61
184_V420_L0.7200.61
402_D492_K0.7180.60
11_A68_D0.7170.60
152_N280_S0.7150.60
128_K288_D0.7150.60
77_G80_K0.7140.60
321_G374_P0.7130.60
183_N382_T0.7120.60
151_V196_V0.7100.59
325_N371_Q0.7100.59
135_I174_N0.7070.59
87_K95_A0.7070.59
429_E516_L0.7060.59
126_K129_T0.7050.59
80_K498_V0.7030.59
244_S260_M0.7020.59
515_Q518_N0.7010.58
186_G221_S0.7010.58
26_T30_L0.7000.58
339_D417_H0.6990.58
124_L287_F0.6980.58
163_Y188_H0.6930.58
70_A499_I0.6930.58
25_V59_T0.6920.58
56_N328_F0.6910.57
155_I382_T0.6900.57
29_D32_A0.6900.57
78_A503_F0.6890.57
519_R533_H0.6880.57
75_L495_T0.6880.57
70_A309_A0.6880.57
220_H224_D0.6880.57
135_I175_H0.6870.57
410_H476_E0.6860.57
322_I500_L0.6860.57
120_V266_W0.6850.57
353_N374_P0.6850.57
112_D115_D0.6820.56
67_Q309_A0.6820.56
83_F99_V0.6820.56
10_A13_Q0.6810.56
172_Y476_E0.6810.56
111_V116_V0.6800.56
159_D280_S0.6800.56
304_F314_P0.6790.56
104_R108_P0.6770.56
152_N164_M0.6750.56
317_L472_I0.6730.55
318_A492_K0.6720.55
42_S54_S0.6720.55
241_A261_F0.6710.55
97_L109_I0.6700.55
31_F536_S0.6700.55
79_I494_F0.6690.55
69_L322_I0.6690.55
186_G339_D0.6690.55
532_S538_N0.6670.55
211_T216_M0.6660.55
204_L283_L0.6650.55
539_G542_N0.6640.54
21_E62_T0.6630.54
9_T12_W0.6620.54
80_K318_A0.6620.54
128_K131_S0.6620.54
492_K496_Q0.6620.54
429_E519_R0.6610.54
151_V193_L0.6600.54
141_G145_K0.6590.54
45_F49_M0.6580.54
197_N200_T0.6570.54
103_N115_D0.6570.54
523_E538_N0.6550.53
370_Y501_N0.6550.53
334_A401_C0.6550.53
353_N376_I0.6540.53
475_R484_A0.6540.53
176_L284_S0.6540.53
377_W428_T0.6520.53
79_I305_S0.6520.53
455_D458_V0.6510.53
152_N206_A0.6500.53
273_L486_I0.6490.53
22_M30_L0.6490.53
108_P121_N0.6490.53
440_V454_L0.6490.53
440_V463_F0.6490.53
49_M297_A0.6470.53
353_N496_Q0.6460.52
231_G236_V0.6460.52
173_K176_L0.6450.52
418_Q421_L0.6440.52
403_F424_F0.6430.52
130_F134_I0.6430.52
19_F324_Y0.6430.52
342_M345_F0.6420.52
471_S536_S0.6400.52
123_V126_K0.6400.52
458_V462_V0.6400.52
376_I387_A0.6400.52
16_Q329_G0.6400.52
389_Y392_I0.6400.52
300_M484_A0.6400.52
121_N124_L0.6380.52
170_R191_E0.6350.51
135_I173_K0.6340.51
308_P311_K0.6340.51
121_N291_V0.6330.51
333_E492_K0.6330.51
155_I214_E0.6320.51
300_M317_L0.6310.51
382_T512_L0.6290.51
415_D525_K0.6290.51
243_L263_F0.6270.50
295_S480_F0.6250.50
11_A14_A0.6240.50
382_T420_L0.6240.50
203_F240_F0.6230.50
132_E288_D0.6220.50
307_T313_L0.6210.50
523_E541_I0.6200.49
163_Y182_S0.6200.49
121_N125_E0.6200.49
73_C503_F0.6200.49
127_M279_L0.6200.49
339_D411_N0.6180.49
109_I116_V0.6170.49
125_E129_T0.6160.49
526_D529_E0.6150.49
16_Q19_F0.6140.49
213_Q518_N0.6140.49
14_A62_T0.6100.48
474_L478_T0.6100.48
25_V33_K0.6090.48
133_A259_N0.6090.48
441_E454_L0.6090.48
58_I67_Q0.6080.48
57_R328_F0.6080.48
132_E287_F0.6050.48
140_K145_K0.6050.48
247_A262_E0.6050.48
437_R457_V0.6020.47
70_A75_L0.6020.47
193_L196_V0.6010.47
159_D164_M0.5990.47
76_A308_P0.5990.47
93_N453_T0.5980.47
95_A99_V0.5970.47
211_T263_F0.5950.47
45_F475_R0.5950.47
379_E383_N0.5950.47
177_N195_K0.5920.46
110_L115_D0.5900.46
227_L232_D0.5890.46
454_L459_P0.5880.46
404_I485_L0.5870.46
384_G387_A0.5870.46
339_D410_H0.5860.46
436_S440_V0.5860.46
502_I505_F0.5850.46
226_F239_H0.5840.45
338_Y381_G0.5840.45
75_L82_M0.5840.45
66_L323_W0.5840.45
165_V285_I0.5820.45
198_P295_S0.5820.45
332_T392_I0.5820.45
217_T416_H0.5810.45
55_K428_T0.5790.45
132_E138_E0.5780.45
159_D182_S0.5780.45
347_A508_W0.5770.45
118_P122_A0.5750.44
481_S484_A0.5750.44
172_Y410_H0.5730.44
19_F22_M0.5720.44
304_F494_F0.5720.44
300_M314_P0.5710.44
22_M59_T0.5710.44
339_D412_P0.5700.44
325_N374_P0.5690.44
293_L297_A0.5690.44
277_I280_S0.5680.44
14_A17_K0.5670.44
27_I470_N0.5670.44
203_F501_N0.5670.44
361_V367_V0.5660.43
91_T363_R0.5650.43
164_M482_L0.5650.43
123_V250_V0.5650.43
496_Q500_L0.5650.43
411_N414_S0.5640.43
43_A63_L0.5640.43
244_S253_F0.5630.43
460_F503_F0.5630.43
332_T376_I0.5620.43
165_V346_A0.5620.43
524_L541_I0.5600.43
49_M484_A0.5590.43
172_Y478_T0.5590.43
352_G505_F0.5590.43
63_L320_I0.5590.43
241_A259_N0.5580.43
463_F517_A0.5580.43
516_L520_I0.5570.42
41_F63_L0.5560.42
342_M404_I0.5560.42
516_L533_H0.5560.42
400_P468_P0.5560.42
188_H382_T0.5540.42
331_E398_M0.5530.42
41_F59_T0.5530.42
248_K251_G0.5530.42
132_E136_S0.5530.42
315_V499_I0.5530.42
64_A67_Q0.5510.42
440_V462_V0.5510.42
407_A544_Y0.5500.42
70_A315_V0.5490.42
163_Y379_E0.5480.42
74_D78_A0.5480.42
421_L424_F0.5480.42
107_T298_H0.5480.42
18_H21_E0.5470.41
316_L320_I0.5470.41
530_I538_N0.5460.41
405_A425_F0.5450.41
142_Y235_H0.5440.41
209_T217_T0.5440.41
524_L545_K0.5430.41
317_L492_K0.5430.41
27_I433_F0.5420.41
250_V256_D0.5420.41
241_A250_V0.5420.41
27_I328_F0.5420.41
10_A14_A0.5410.41
42_S539_G0.5410.41
438_E455_D0.5400.41
363_R503_F0.5390.41
424_F469_T0.5380.40
330_A400_P0.5370.40
343_H347_A0.5370.40
209_T216_M0.5360.40
101_L266_W0.5360.40
320_I353_N0.5360.40
22_M27_I0.5350.40
69_L327_F0.5340.40
152_N479_P0.5340.40
430_A512_L0.5330.40
170_R341_Y0.5330.40
324_Y398_M0.5320.40
389_Y463_F0.5310.40
170_R343_H0.5300.40
526_D530_I0.5300.40
164_M209_T0.5300.40
313_L459_P0.5290.39
387_A486_I0.5290.39
425_F541_I0.5280.39
260_M263_F0.5280.39
238_K259_N0.5270.39
188_H388_F0.5270.39
105_S115_D0.5270.39
54_S536_S0.5270.39
137_G144_G0.5270.39
74_D81_S0.5260.39
231_G235_H0.5260.39
45_F50_L0.5250.39
17_K33_K0.5250.39
404_I481_S0.5250.39
155_I183_N0.5240.39
116_V120_V0.5240.39
527_D531_S0.5240.39
515_Q520_I0.5240.39
475_R481_S0.5240.39
348_Y352_G0.5230.39
87_K252_E0.5230.39
522_P527_D0.5210.39
17_K21_E0.5200.38
164_M182_S0.5200.38
531_S542_N0.5200.38
123_V263_F0.5190.38
124_L128_K0.5190.38
142_Y226_F0.5170.38
333_E400_P0.5160.38
376_I544_Y0.5160.38
271_Y321_G0.5160.38
348_Y486_I0.5160.38
339_D416_H0.5140.38
21_E24_D0.5140.38
163_Y170_R0.5140.38
471_S530_I0.5130.38
475_R478_T0.5120.38
166_T348_Y0.5120.38
241_A260_M0.5110.38
21_E65_K0.5110.38
142_Y229_A0.5100.37
150_V178_M0.5100.37
119_E264_W0.5100.37
335_I376_I0.5100.37
55_K432_A0.5090.37
438_E442_Q0.5080.37
316_L466_N0.5080.37
533_H541_I0.5080.37
181_V192_V0.5080.37
245_T262_E0.5080.37
340_Q380_P0.5070.37
346_A379_E0.5070.37
114_K118_P0.5060.37
127_M276_A0.5060.37
12_W16_Q0.5050.37
90_R93_N0.5050.37
453_T461_K0.5050.37
138_E228_K0.5050.37
425_F540_L0.5030.37
343_H469_T0.5030.37
263_F517_A0.5030.37
45_F480_F0.5030.37
149_D176_L0.5020.37
347_A380_P0.5020.37
51_V353_N0.5010.36
452_A455_D0.5010.36
440_V453_T0.5010.36
437_R455_D0.5010.36
18_H61_E0.5000.36
25_V29_D0.5000.36
471_S540_L0.5000.36
91_T501_N0.5000.36
251_G260_M0.5000.36
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1t10A 2 0.9909 100 0.152 Contact Map
2o2cA 2 0.9982 100 0.154 Contact Map
3hjbA 4 0.9982 100 0.159 Contact Map
2cxnA 2 0.9945 100 0.166 Contact Map
3ljkA 2 0.9836 100 0.17 Contact Map
3qkiA 2 0.9745 100 0.171 Contact Map
3ujhA 2 0.9818 100 0.176 Contact Map
2wu8A 2 0.9763 100 0.179 Contact Map
4em6D 2 0.9909 100 0.24 Contact Map
3ff1A 4 0.776 100 0.477 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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