GREMLIN Database
FTSB - Cell division protein FtsB
UniProt: P0A6S5 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13111
Length: 103 (90)
Sequences: 657 (455)
Seq/√Len: 48.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
47_K51_D3.1551.00
53_L57_I3.0521.00
46_L49_R3.0281.00
59_D63_G2.9701.00
16_Q20_W2.7941.00
56_E77_M2.4261.00
22_G25_G2.2711.00
21_F27_H2.2211.00
24_N57_I2.2111.00
18_S23_K2.1881.00
70_R74_E2.0681.00
68_E79_R1.8660.99
21_F25_G1.8180.99
33_N37_A1.6050.97
35_D38_A1.5750.97
39_Q43_N1.5390.97
18_S26_I1.5270.96
74_E86_R1.5070.96
24_N29_Y1.4580.95
28_D31_R1.4060.94
55_A66_A1.3990.94
70_R77_M1.3540.93
16_Q70_R1.3390.93
17_Y21_F1.2990.92
23_K81_G1.2920.91
48_A67_L1.2910.91
42_T45_K1.2460.90
57_I86_R1.2440.90
18_S28_D1.2400.90
18_S25_G1.2140.89
51_D56_E1.1830.87
37_A40_Q1.1650.87
17_Y66_A1.1500.86
37_A41_A1.1440.86
6_L9_L1.1150.84
68_E77_M1.1070.84
59_D74_E1.0710.82
24_N54_F1.0460.80
11_I91_A1.0340.79
11_I79_R1.0230.78
15_L73_N1.0180.78
18_S85_Y1.0150.78
24_N86_R1.0140.78
9_L15_L1.0140.78
85_Y89_P1.0030.77
30_T37_A0.9520.73
15_L89_P0.9510.73
59_D84_F0.9420.72
70_R84_F0.9370.72
23_K28_D0.9310.72
36_V88_V0.9310.72
6_L10_A0.9210.71
34_D37_A0.9200.71
39_Q61_N0.9060.69
41_A45_K0.9010.69
4_L84_F0.8880.68
8_L46_L0.8760.67
36_V52_Q0.8690.66
54_F61_N0.8690.66
48_A51_D0.8530.65
69_E87_L0.8520.65
15_L76_S0.8470.64
43_N46_L0.8470.64
55_A59_D0.8310.63
9_L13_V0.8170.61
59_D66_A0.8160.61
84_F88_V0.8150.61
12_L41_A0.8070.60
24_N67_L0.8060.60
29_Y57_I0.8040.60
66_A70_R0.7980.60
29_Y86_R0.7850.58
33_N40_Q0.7800.58
31_R53_L0.7730.57
34_D38_A0.7700.57
25_G39_Q0.7650.56
58_D87_L0.7640.56
20_W71_A0.7580.56
51_D91_A0.7540.55
84_F87_L0.7490.55
61_N73_N0.7280.53
53_L73_N0.7240.52
23_K32_V0.7220.52
40_Q58_D0.7220.52
28_D87_L0.7200.52
17_Y31_R0.7190.52
3_K81_G0.7140.51
27_H30_T0.7080.51
66_A84_F0.7080.51
10_A14_W0.7030.50
66_A88_V0.6890.49
25_G36_V0.6750.47
18_S56_E0.6740.47
64_Q88_V0.6680.47
4_L65_E0.6670.47
73_N80_P0.6660.46
36_V59_D0.6610.46
69_E75_L0.6510.45
56_E65_E0.6510.45
3_K88_V0.6490.45
17_Y50_N0.6430.44
29_Y54_F0.6370.44
56_E64_Q0.6250.42
5_T67_L0.6230.42
26_I30_T0.6210.42
80_P91_A0.6210.42
36_V49_R0.6200.42
7_L44_A0.6090.41
28_D35_D0.6070.41
36_V39_Q0.6010.40
8_L77_M0.5960.40
36_V62_G0.5910.39
30_T33_N0.5890.39
18_S27_H0.5870.39
6_L11_I0.5750.38
45_K65_E0.5710.37
43_N88_V0.5700.37
41_A51_D0.5680.37
40_Q44_A0.5600.36
83_T86_R0.5580.36
15_L85_Y0.5550.36
75_L84_F0.5490.35
69_E86_R0.5470.35
37_A47_K0.5430.35
29_Y85_Y0.5370.34
31_R44_A0.5350.34
18_S53_L0.5350.34
29_Y32_V0.5320.34
54_F78_T0.5320.34
7_L79_R0.5180.32
30_T79_R0.5120.32
69_E77_M0.5120.32
31_R38_A0.5110.32
50_N60_L0.5030.31
14_W31_R0.5000.31
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4iffA 2 0.4951 97.9 0.78 Contact Map
4dznA 3 0.3107 72.4 0.893 Contact Map
4etpA 1 0.7282 61.3 0.9 Contact Map
1kd8A 1 0.3398 47.7 0.908 Contact Map
2yy0A 6 0.5146 36.3 0.914 Contact Map
1a93B 1 0.3107 36.1 0.914 Contact Map
4cgkA 3 0.5534 35.5 0.915 Contact Map
3w92A 3 0.301 33.3 0.916 Contact Map
2hy6A 3 0.301 27.7 0.919 Contact Map
3u06A 2 0.7573 27.2 0.92 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0056 seconds.